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PMC:2664230 / 0-544 JSONTXT

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bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Speculation
T54 18-28 Regulation denotes Regulation
T55 32-37 Protein denotes TNF-α
T56 38-48 Gene_expression denotes Production
T57 204-210 Regulation denotes effect true
T58 294-321 Protein denotes tumor necrosis factor-alpha
T59 323-328 Protein denotes TNF-α
T60 330-340 Gene_expression denotes production
T61 423-433 Gene_expression denotes production
T62 437-442 Protein denotes TNF-α
T63 443-452 Positive_regulation denotes following
R748 T55 T56 themeOf TNF-α,Production
R749 T56 T54 themeOf Production,Regulation
R750 T58 T60 themeOf tumor necrosis factor-alpha,production
R751 T60 T57 themeOf production,effect
R752 T61 T63 themeOf production,following
R753 T62 T61 themeOf TNF-α,production

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T451 0-8 NN denotes Insights
T452 9-13 IN denotes into
T453 14-17 DT denotes the
T454 18-28 NN denotes Regulation
T455 29-31 IN denotes of
T456 32-37 NN denotes TNF-α
T457 38-48 NN denotes Production
T458 49-51 IN denotes in
T459 52-57 JJ denotes Human
T460 58-69 JJ denotes Mononuclear
T461 70-75 NN denotes Cells
T462 75-76 -COLON- denotes :
T463 77-80 DT denotes The
T464 81-88 NN denotes Effects
T465 89-91 IN denotes of
T466 92-104 JJ denotes Non-Specific
T467 105-122 NN denotes Phosphodiesterase
T468 123-133 NN denotes Inhibition
T469 145-154 NN denotes OBJECTIVE
T470 155-158 DT denotes The
T471 159-168 NN denotes objective
T472 169-171 IN denotes of
T473 172-176 DT denotes this
T474 177-182 NN denotes study
T475 183-186 VB denotes was
T476 187-189 TO denotes to
T477 190-199 VB denotes determine
T478 200-203 DT denotes the
T479 204-210 NN denotes effect
T480 211-213 IN denotes of
T481 214-225 JJ denotes nonspecific
T482 226-243 NN denotes phosphodiesterase
T483 244-254 NN denotes inhibition
T484 255-257 IN denotes on
T485 258-271 NN denotes transcription
T486 272-278 NN denotes factor
T487 279-289 NN denotes activation
T488 290-293 CC denotes and
T489 294-299 NN denotes tumor
T490 300-308 NN denotes necrosis
T491 309-321 NN denotes factor-alpha
T492 322-323 -LRB- denotes (
T493 323-328 NN denotes TNF-α
T494 328-329 -RRB- denotes )
T495 330-340 NN denotes production
T496 341-343 IN denotes in
T497 344-362 NN denotes lipopolysaccharide
T498 363-364 -LRB- denotes (
T499 364-367 NN denotes LPS
T500 367-368 -RRB- denotes )
T501 368-379 JJ denotes -stimulated
T502 380-385 JJ denotes human
T503 386-397 JJ denotes mononuclear
T504 398-403 NN denotes cells
T505 406-418 NN denotes INTRODUCTION
T506 419-422 DT denotes The
T507 423-433 NN denotes production
T508 434-436 IN denotes of
T509 437-442 NN denotes TNF-α
T510 443-452 VB denotes following
T511 453-456 NN denotes LPS
T512 457-468 NN denotes stimulation
T513 469-471 VB denotes is
T514 472-475 CD denotes one
T515 476-478 IN denotes of
T516 479-482 DT denotes the
T517 483-486 JJ denotes key
T518 487-492 NN denotes steps
T519 493-495 IN denotes in
T520 496-505 JJ denotes bacterial
T521 506-512 NN denotes sepsis
T522 513-516 CC denotes and
T523 517-529 NN denotes inflammation
T524 531-534 DT denotes The
T525 535-544 NN denotes mechanism
T2791 172-176 DT denotes this
T2792 177-182 NN denotes study
T2793 183-186 VB denotes was
R349 T451 T452 arg1Of Insights,into
R350 T451 T462 arg1Of Insights,:
R351 T454 T452 arg2Of Regulation,into
R352 T454 T453 arg1Of Regulation,the
R353 T454 T455 arg1Of Regulation,of
R354 T454 T458 arg1Of Regulation,in
R355 T457 T455 arg2Of Production,of
R356 T457 T456 arg1Of Production,TNF-α
R357 T461 T458 arg2Of Cells,in
R358 T461 T459 arg1Of Cells,Human
R359 T461 T460 arg1Of Cells,Mononuclear
R360 T464 T463 arg1Of Effects,The
R361 T464 T465 arg1Of Effects,of
R362 T468 T465 arg2Of Inhibition,of
R363 T468 T466 arg1Of Inhibition,Non-Specific
R364 T468 T467 arg1Of Inhibition,Phosphodiesterase
R365 T471 T470 arg1Of objective,The
R366 T471 T472 arg1Of objective,of
R367 T471 T475 arg1Of objective,was
R368 T474 T472 arg2Of study,of
R369 T474 T473 arg1Of study,this
R370 T477 T475 arg2Of determine,was
R371 T477 T476 arg1Of determine,to
R372 T479 T477 arg2Of effect,determine
R373 T479 T478 arg1Of effect,the
R374 T479 T480 arg1Of effect,of
R375 T479 T484 arg1Of effect,on
R376 T483 T480 arg2Of inhibition,of
R377 T483 T481 arg1Of inhibition,nonspecific
R378 T483 T482 arg1Of inhibition,phosphodiesterase
R379 T487 T485 arg1Of activation,transcription
R380 T487 T486 arg1Of activation,factor
R381 T487 T488 arg1Of activation,and
R382 T488 T484 arg2Of and,on
R383 T488 T496 arg1Of and,in
R384 T491 T489 arg1Of factor-alpha,tumor
R385 T491 T490 arg1Of factor-alpha,necrosis
R386 T491 T492 arg1Of factor-alpha,(
R387 T493 T492 arg2Of TNF-α,(
R388 T494 T492 arg3Of ),(
R389 T495 T488 arg2Of production,and
R390 T495 T491 arg1Of production,factor-alpha
R391 T499 T498 arg2Of LPS,(
R392 T500 T498 arg3Of ),(
R393 T501 T497 arg1Of -stimulated,lipopolysaccharide
R394 T501 T498 arg1Of -stimulated,(
R395 T504 T496 arg2Of cells,in
R396 T504 T501 arg1Of cells,-stimulated
R397 T504 T502 arg1Of cells,human
R398 T504 T503 arg1Of cells,mononuclear
R399 T507 T506 arg1Of production,The
R400 T507 T508 arg1Of production,of
R401 T507 T510 arg1Of production,following
R402 T507 T513 arg1Of production,is
R403 T509 T508 arg2Of TNF-α,of
R404 T512 T510 arg2Of stimulation,following
R405 T512 T511 arg1Of stimulation,LPS
R406 T514 T513 arg2Of one,is
R407 T514 T515 arg1Of one,of
R408 T518 T515 arg2Of steps,of
R409 T518 T516 arg1Of steps,the
R410 T518 T517 arg1Of steps,key
R411 T518 T519 arg1Of steps,in
R412 T521 T522 arg1Of sepsis,and
R413 T522 T519 arg2Of and,in
R414 T522 T520 arg1Of and,bacterial
R415 T523 T522 arg2Of inflammation,and
R416 T525 T524 arg1Of mechanism,The
R2218 T2792 T2791 arg1Of study,this
R2219 T2792 T2793 arg1Of study,was

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T162 244-254 NN denotes inhibition
T163 255-257 IN denotes on
T164 258-271 NN denotes transcription
T165 272-278 NN denotes factor
T166 279-289 NN denotes activation
T167 290-293 CC denotes and
T168 294-299 NN denotes tumor
T169 300-308 NN denotes necrosis
T170 309-321 NN denotes factor-alpha
T171 322-323 -LRB- denotes (
T172 323-328 NNP denotes TNF-α
T173 328-329 -RRB- denotes )
T174 330-340 NN denotes production
T175 341-343 IN denotes in
T176 344-362 NN denotes lipopolysaccharide
T177 363-364 -LRB- denotes (
T178 364-367 NNP denotes LPS
T179 367-368 -RRB- denotes )
T180 368-369 : denotes -
T181 369-379 VBN denotes stimulated
T182 380-385 JJ denotes human
T183 386-397 NN denotes mononuclear
T184 398-403 NNS denotes cells
T185 403-404 . denotes .
T186 406-418 NNP denotes INTRODUCTION
T187 419-422 DT denotes The
T188 423-433 NN denotes production
T189 434-436 IN denotes of
T190 437-442 NNP denotes TNF-α
T191 443-452 VBG denotes following
T192 453-456 NNP denotes LPS
T193 457-468 NN denotes stimulation
T194 469-471 VBZ denotes is
T195 472-475 CD denotes one
T196 476-478 IN denotes of
T197 479-482 DT denotes the
T198 483-486 JJ denotes key
T199 487-492 NNS denotes steps
T200 493-495 IN denotes in
T201 496-505 JJ denotes bacterial
T202 506-512 NN denotes sepsis
T203 513-516 CC denotes and
T204 517-529 NN denotes inflammation
T205 529-530 . denotes .
T206 531-534 DT denotes The
T207 535-544 NN denotes mechanism
T2464 172-176 DT denotes this
T2465 177-182 NN denotes study
T2466 183-186 VBD denotes was
T130 0-8 NNPS denotes Insights
T131 9-13 IN denotes into
T132 14-17 DT denotes the
T133 18-28 NN denotes Regulation
T134 29-31 IN denotes of
T135 32-37 NNP denotes TNF-α
T136 38-48 NNP denotes Production
T137 49-51 IN denotes in
T138 52-57 NNP denotes Human
T139 58-69 NNP denotes Mononuclear
T140 70-75 NNPS denotes Cells
T141 75-76 : denotes :
T142 77-80 DT denotes The
T143 81-88 NNPS denotes Effects
T144 89-91 IN denotes of
T145 92-104 NNP denotes Non-Specific
T146 105-122 NNP denotes Phosphodiesterase
T147 123-133 NNP denotes Inhibition
T148 145-154 NNP denotes OBJECTIVE
T149 155-158 DT denotes The
T150 159-168 NN denotes objective
T151 169-171 IN denotes of
T152 172-176 DT denotes this
T153 177-182 NN denotes study
T154 183-186 VBD denotes was
T155 187-189 TO denotes to
T156 190-199 VB denotes determine
T157 200-203 DT denotes the
T158 204-210 NN denotes effect
T159 211-213 IN denotes of
T160 214-225 JJ denotes nonspecific
T161 226-243 NN denotes phosphodiesterase
R78 T180 T162 punct -,inhibition
R79 T181 T154 conj stimulated,was
R80 T182 T184 amod human,cells
R81 T183 T184 compound mononuclear,cells
R82 T184 T181 dobj cells,stimulated
R83 T185 T154 punct .,was
R84 T186 T194 advmod INTRODUCTION,is
R85 T187 T188 det The,production
R86 T188 T194 nsubj production,is
R87 T189 T188 prep of,production
R88 T190 T189 pobj TNF-α,of
R89 T191 T188 prep following,production
R90 T192 T193 compound LPS,stimulation
R91 T193 T191 pobj stimulation,following
R92 T194 T194 ROOT is,is
R93 T195 T194 attr one,is
R94 T196 T195 prep of,one
R95 T197 T199 det the,steps
R96 T198 T199 amod key,steps
R97 T199 T196 pobj steps,of
R98 T200 T199 prep in,steps
R99 T201 T202 amod bacterial,sepsis
R103 T205 T194 punct .,is
R104 T206 T207 det The,mechanism
R765 T140 T137 pobj Cells,in
R766 T141 T143 punct :,Effects
R767 T142 T143 det The,Effects
R768 T143 T130 appos Effects,Insights
R769 T144 T143 prep of,Effects
R770 T145 T146 compound Non-Specific,Phosphodiesterase
R771 T146 T148 compound Phosphodiesterase,OBJECTIVE
R772 T147 T148 compound Inhibition,OBJECTIVE
R773 T148 T143 appos OBJECTIVE,Effects
R774 T149 T150 det The,objective
R775 T150 T154 nsubj objective,was
R776 T151 T150 prep of,objective
R777 T152 T153 det this,study
R778 T153 T151 pobj study,of
R779 T154 T154 ROOT was,was
R780 T155 T156 aux to,determine
R781 T156 T154 xcomp determine,was
R782 T157 T158 det the,effect
R783 T158 T156 dobj effect,determine
R784 T159 T158 prep of,effect
R785 T160 T162 amod nonspecific,inhibition
R786 T161 T162 compound phosphodiesterase,inhibition
R1891 T2464 T2465 det this,study
R100 T202 T200 pobj sepsis,in
R101 T203 T202 cc and,sepsis
R102 T204 T202 conj inflammation,sepsis
R60 T162 T159 pobj inhibition,of
R61 T163 T162 prep on,inhibition
R62 T164 T165 compound transcription,factor
R63 T165 T166 compound factor,activation
R64 T166 T163 pobj activation,on
R65 T167 T166 cc and,activation
R66 T168 T169 compound tumor,necrosis
R67 T169 T170 compound necrosis,factor-alpha
R68 T170 T166 conj factor-alpha,activation
R69 T171 T172 punct (,TNF-α
R70 T172 T170 appos TNF-α,factor-alpha
R71 T173 T170 punct ),factor-alpha
R72 T174 T166 conj production,activation
R73 T175 T174 prep in,production
R74 T176 T175 pobj lipopolysaccharide,in
R75 T177 T178 punct (,LPS
R76 T178 T176 appos LPS,lipopolysaccharide
R77 T179 T176 punct ),lipopolysaccharide
R755 T130 T130 ROOT Insights,Insights
R756 T131 T130 prep into,Insights
R757 T132 T133 det the,Regulation
R758 T133 T131 pobj Regulation,into
R759 T134 T133 prep of,Regulation
R760 T135 T136 compound TNF-α,Production
R761 T136 T134 pobj Production,of
R762 T137 T136 prep in,Production
R763 T138 T139 compound Human,Mononuclear
R764 T139 T140 compound Mononuclear,Cells

GO-BP

Id Subject Object Predicate Lexical cue
T824 18-28 http://purl.obolibrary.org/obo/GO_0065007 denotes Regulation
T825 18-48 http://purl.obolibrary.org/obo/GO_0032680 denotes Regulation of TNF-α Production
T826 323-340 http://purl.obolibrary.org/obo/GO_0032680 denotes TNF-α) production
T827 423-442 http://purl.obolibrary.org/obo/GO_0032680 denotes production of TNF-α
T829 18-37 http://purl.obolibrary.org/obo/GO_0042534 denotes Regulation of TNF-α
T830 18-37 http://purl.obolibrary.org/obo/GO_1904467 denotes Regulation of TNF-α
T831 18-48 http://purl.obolibrary.org/obo/GO_0032720 denotes Regulation of TNF-α Production
T832 18-48 http://purl.obolibrary.org/obo/GO_0032760 denotes Regulation of TNF-α Production
T833 32-48 http://purl.obolibrary.org/obo/GO_0032640 denotes TNF-α Production
T834 323-340 http://purl.obolibrary.org/obo/GO_0032640 denotes TNF-α) production
T835 423-442 http://purl.obolibrary.org/obo/GO_0032640 denotes production of TNF-α
T836 423-440 http://purl.obolibrary.org/obo/GO_0032640 denotes production of TNF
T837 105-122 http://purl.obolibrary.org/obo/GO_0008081 denotes Phosphodiesterase
T838 226-243 http://purl.obolibrary.org/obo/GO_0008081 denotes phosphodiesterase
T843 244-278 http://purl.obolibrary.org/obo/GO_1901484 denotes inhibition on transcription factor
T844 244-278 http://purl.obolibrary.org/obo/GO_0043433 denotes inhibition on transcription factor
T845 244-278 http://purl.obolibrary.org/obo/GO_0032792 denotes inhibition on transcription factor
T846 258-271 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T848 258-289 http://purl.obolibrary.org/obo/GO_0051091 denotes transcription factor activation
T849 258-289 http://purl.obolibrary.org/obo/GO_0032793 denotes transcription factor activation
T851 258-289 http://purl.obolibrary.org/obo/GO_1901485 denotes transcription factor activation
T852 300-308 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T853 300-308 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T854 300-308 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T855 300-308 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T856 517-529 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation

GO-MF

Id Subject Object Predicate Lexical cue
T864 105-122 http://purl.obolibrary.org/obo/GO_0008081 denotes Phosphodiesterase
T865 226-243 http://purl.obolibrary.org/obo/GO_0008081 denotes phosphodiesterase

GO-CC

Id Subject Object Predicate Lexical cue
T881 398-403 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T110 0-76 Sentence denotes Insights into the Regulation of TNF-α Production in Human Mononuclear Cells:
T111 77-133 Sentence denotes The Effects of Non-Specific Phosphodiesterase Inhibition
T112 145-154 Sentence denotes OBJECTIVE
T113 155-404 Sentence denotes The objective of this study was to determine the effect of nonspecific phosphodiesterase inhibition on transcription factor activation and tumor necrosis factor-alpha (TNF-α) production in lipopolysaccharide (LPS)-stimulated human mononuclear cells.
T114 406-418 Sentence denotes INTRODUCTION
T115 419-530 Sentence denotes The production of TNF-α following LPS stimulation is one of the key steps in bacterial sepsis and inflammation.
T1 0-76 Sentence denotes Insights into the Regulation of TNF-α Production in Human Mononuclear Cells:
T2 77-133 Sentence denotes The Effects of Non-Specific Phosphodiesterase Inhibition
T3 136-144 Sentence denotes Abstract
T4 145-154 Sentence denotes OBJECTIVE
T5 155-404 Sentence denotes The objective of this study was to determine the effect of nonspecific phosphodiesterase inhibition on transcription factor activation and tumor necrosis factor-alpha (TNF-α) production in lipopolysaccharide (LPS)-stimulated human mononuclear cells.
T6 406-418 Sentence denotes INTRODUCTION
T7 419-530 Sentence denotes The production of TNF-α following LPS stimulation is one of the key steps in bacterial sepsis and inflammation.

events-check-again

Id Subject Object Predicate Lexical cue Speculation
T884 18-28 Regulation denotes Regulation
T885 32-37 Protein denotes TNF-α
T886 38-48 Gene_expression denotes Production
T887 204-210 Regulation denotes effect true
T888 294-321 Protein denotes tumor necrosis factor-alpha
T889 323-328 Protein denotes TNF-α
T890 330-340 Gene_expression denotes production
T891 423-433 Gene_expression denotes production
T892 437-442 Protein denotes TNF-α
T893 443-452 Positive_regulation denotes following
R648 T885 T886 themeOf TNF-α,Production
R649 T886 T884 themeOf Production,Regulation
R650 T888 T890 themeOf tumor necrosis factor-alpha,production
R651 T890 T887 themeOf production,effect
R652 T891 T893 themeOf production,following
R653 T892 T891 themeOf TNF-α,production

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T912 32-37 Protein denotes TNF-α
T913 92-95 Protein denotes Non
T914 96-122 Protein denotes Specific Phosphodiesterase
T915 38-48 Gene_expression denotes Production
T916 123-133 Negative_regulation denotes Inhibition
T917 18-28 Regulation denotes Regulation
T918 81-88 Regulation denotes Effects
T919 294-321 Protein denotes tumor necrosis factor-alpha
T920 323-328 Protein denotes TNF-α
T921 330-340 Gene_expression denotes production
T922 330-340 Gene_expression denotes production
T923 279-289 Positive_regulation denotes activation
T924 279-289 Positive_regulation denotes activation
T925 204-210 Regulation denotes effect
T926 204-210 Regulation denotes effect
T927 437-442 Protein denotes TNF-α
T928 423-433 Gene_expression denotes production
T929 457-468 Positive_regulation denotes stimulation
R665 T912 T915 themeOf TNF-α,Production
R666 T914 T916 themeOf Specific Phosphodiesterase,Inhibition
R667 T915 T917 themeOf Production,Regulation
R668 T916 T918 themeOf Inhibition,Effects
R669 T919 T921 themeOf tumor necrosis factor-alpha,production
R670 T920 T922 themeOf TNF-α,production
R671 T921 T923 themeOf production,activation
R672 T922 T924 themeOf production,activation
R673 T923 T925 themeOf activation,effect
R674 T924 T926 themeOf activation,effect
R675 T927 T928 themeOf TNF-α,production
R676 T928 T929 themeOf production,stimulation

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T757 32-35 P01375 denotes TNF
T758 32-37 P01375 denotes TNF-α
T759 294-315 P01375 denotes tumor necrosis factor
T760 323-326 P01375 denotes TNF
T761 323-328 P01375 denotes TNF-α
T762 437-440 P01375 denotes TNF
T763 437-442 P01375 denotes TNF-α

test2

Id Subject Object Predicate Lexical cue Speculation
T29 18-28 Regulation denotes Regulation
T30 32-37 Protein denotes TNF-α
T31 38-48 Gene_expression denotes Production true
T32 294-321 Protein denotes tumor necrosis factor-alpha
T33 323-328 Protein denotes TNF-α
T34 330-340 Gene_expression denotes production
T35 423-433 Gene_expression denotes production
T36 437-442 Protein denotes TNF-α
T37 443-452 Positive_regulation denotes following
R18 T30 T31 themeOf TNF-α,Production
R19 T31 T29 themeOf Production,Regulation
R20 T32 T34 themeOf tumor necrosis factor-alpha,production
R21 T35 T37 themeOf production,following
R22 T36 T35 themeOf TNF-α,production