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PMC:2626671 / 19196-20867 JSONTXT

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pmc-enju-pas

Id Subject Object Predicate Lexical cue
T21280 10-15 NN denotes Runx3
T21281 16-24 VB denotes controls
T21282 25-30 NN denotes Eomes
T21283 30-31 -COMMA- denotes ,
T21284 32-40 NN denotes perforin
T21285 40-41 -COMMA- denotes ,
T21286 42-50 NN denotes granzyme
T21287 51-52 NN denotes B
T21288 52-53 -COMMA- denotes ,
T21289 54-57 CC denotes and
T21290 58-63 NN denotes IFN-γ
T21291 64-74 NN denotes expression
T21292 75-77 IN denotes in
T21293 78-86 NN denotes effector
T21294 87-91 NN denotes CTLs
T21295 93-101 NN denotes Runx3+/+
T21296 102-104 CC denotes or
T21297 105-113 NN denotes Runx3−/−
T21298 114-118 JJ denotes CD8+
T21299 119-120 NN denotes T
T21300 121-126 NN denotes cells
T21301 127-131 VB denotes were
T21302 132-141 VB denotes activated
T21303 142-145 CC denotes and
T21304 146-156 VB denotes transduced
T21305 157-161 IN denotes with
T21306 162-174 NN denotes retroviruses
T21307 175-182 VB denotes bearing
T21308 183-185 DT denotes an
T21309 186-191 JJ denotes empty
T21310 192-200 NN denotes IRES-GFP
T21311 201-209 NN denotes cassette
T21312 210-211 -LRB- denotes (
T21313 211-214 NN denotes GFP
T21314 214-215 -RRB- denotes )
T21315 216-218 CC denotes or
T21316 219-223 RB denotes also
T21317 224-232 VB denotes encoding
T21318 233-243 NN denotes Eomes-VP16
T21319 244-245 -LRB- denotes (
T21320 245-252 NN denotes Eo-VP16
T21321 252-253 -RRB- denotes )
T21322 254-256 CC denotes or
T21323 257-266 NN denotes Myc-Runx3
T21324 267-268 -LRB- denotes (
T21325 268-273 NN denotes Runx3
T21326 273-274 -RRB- denotes )
T21327 276-279 DT denotes The
T21328 280-289 NN denotes frequency
T21329 290-292 IN denotes of
T21330 293-303 VB denotes transduced
T21331 304-309 NN denotes cells
T21332 310-312 IN denotes in
T21333 313-316 DT denotes the
T21334 317-325 NN denotes cultures
T21335 326-329 VB denotes was
T21336 330-340 JJ denotes equivalent
T21337 341-344 IN denotes for
T21338 345-348 DT denotes all
T21339 349-359 NN denotes constructs
T21340 360-361 -LRB- denotes (
T21341 361-367 CD denotes ∼75–90
T21342 367-368 NN denotes %
T21343 369-373 NN denotes GFP+
T21344 374-379 NN denotes cells
T21345 379-380 -COLON- denotes ;
T21346 381-384 RB denotes not
T21347 385-393 VB denotes depicted
T21348 393-394 -RRB- denotes )
T21349 394-395 -LRB- denotes .
T21350 396-397 NN denotes (
T21351 397-398 -RRB- denotes A
T21352 398-405 NN denotes ) Prote
T21353 405-415 NN denotes in express
T21354 415-417 IN denotes io
T21355 417-427 JJ denotes n in whole
T21356 427-435 NN denotes -cell ex
T21357 435-436 -LRB- denotes t
T21358 436-439 NN denotes rac
T21359 439-440 CD denotes t
T21360 440-441 -RRB- denotes s
T21361 442-445 VB denotes (da
T21362 445-453 VB denotes y 6) was
T21363 454-456 IN denotes an
T21364 456-470 NN denotes alyzed by immu
T21365 482-496 NN denotes Overexpression
T21366 497-499 IN denotes of
T21367 500-510 NN denotes Eomes-VP16
T21368 511-514 MD denotes can
T21369 514-517 RB denotes not
T21370 518-520 VB denotes be
T21371 521-529 VB denotes detected
T21372 530-534 IN denotes with
T21373 535-538 DT denotes the
T21374 539-544 NN denotes Eomes
T21375 545-553 NN denotes antibody
T21376 553-554 -COMMA- denotes ,
T21377 555-557 IN denotes as
T21378 558-561 DT denotes the
T21379 562-572 JJ denotes C-terminal
T21380 573-580 NN denotes epitope
T21381 581-583 VB denotes is
T21382 584-590 IN denotes within
T21383 591-594 DT denotes the
T21384 595-601 NN denotes region
T21385 602-606 WDT denotes that
T21386 607-610 VB denotes has
T21387 611-615 VB denotes been
T21388 616-624 VB denotes replaced
T21389 625-629 IN denotes with
T21390 630-633 DT denotes the
T21391 634-638 NN denotes VP16
T21392 639-654 NN denotes transactivation
T21393 655-662 NN denotes domain.
T21394 663-664 -LRB- denotes (
T21395 664-665 NN denotes B
T21396 665-666 -RRB- denotes )
T21397 667-677 NN denotes Expression
T21398 678-680 IN denotes of
T21399 681-689 NN denotes granzyme
T21400 690-691 NN denotes B
T21401 692-695 CC denotes and
T21402 696-701 NN denotes IFN-γ
T21403 702-707 IN denotes after
T21404 708-715 NN denotes culture
T21405 716-719 IN denotes for
T21406 720-721 CD denotes 6
T21407 722-723 NN denotes d
T21408 724-727 CC denotes and
T21409 728-741 NN denotes restimulation
T21410 742-745 IN denotes for
T21411 746-747 CD denotes 4
T21412 748-749 NN denotes h
T21413 750-754 IN denotes with
T21414 755-758 NN denotes PMA
T21415 759-762 CC denotes and
T21416 763-772 NN denotes ionomycin
T21417 773-776 VB denotes was
T21418 777-787 VB denotes determined
T21419 788-790 IN denotes by
T21420 791-804 JJ denotes intracellular
T21421 805-813 NN denotes staining
T21422 815-818 DT denotes The
T21423 819-829 NN denotes percentage
T21424 830-832 IN denotes of
T21425 833-843 RB denotes positively
T21426 844-851 VB denotes stained
T21427 852-857 NN denotes cells
T21428 858-860 VB denotes is
T21429 861-866 VB denotes shown
T21430 867-872 IN denotes above
T21431 873-876 DT denotes the
T21432 877-881 NN denotes gate
T21433 881-882 -COLON- denotes ;
T21434 883-886 DT denotes the
T21435 887-891 JJ denotes mean
T21436 892-904 NN denotes fluorescence
T21437 905-914 NN denotes intensity
T21438 915-916 -LRB- denotes (
T21439 916-919 NN denotes MFI
T21440 919-920 -RRB- denotes )
T21441 921-923 IN denotes of
T21442 924-932 NN denotes granzyme
T21443 933-934 NN denotes B
T21444 935-943 NN denotes staining
T21445 944-947 IN denotes for
T21446 948-951 DT denotes the
T21447 952-957 JJ denotes total
T21448 958-968 NN denotes population
T21449 969-971 VB denotes is
T21450 972-977 VB denotes shown
T21451 978-983 IN denotes below
T21452 984-987 DT denotes the
T21453 988-992 NN denotes gate
T21454 994-997 DT denotes The
T21455 998-1006 JJ denotes vertical
T21456 1007-1011 JJ denotes gray
T21457 1012-1017 NN denotes lines
T21458 1018-1026 VB denotes indicate
T21459 1027-1030 DT denotes the
T21460 1031-1034 NN denotes MFI
T21461 1035-1038 IN denotes for
T21462 1039-1041 JJ denotes WT
T21463 1042-1046 NN denotes GFP+
T21464 1047-1052 NN denotes cells
T21465 1054-1061 NN denotes Results
T21466 1062-1065 VB denotes are
T21467 1066-1080 JJ denotes representative
T21468 1081-1083 IN denotes of
T21469 1084-1086 IN denotes at
T21470 1087-1092 JJ denotes least
T21471 1093-1096 CD denotes two
T21472 1097-1108 JJ denotes independent
T21473 1109-1121 NN denotes experiments.
T21474 1122-1123 -LRB- denotes (
T21475 1123-1124 NN denotes C
T21476 1124-1125 -RRB- denotes )
T21477 1126-1135 JJ denotes Schematic
T21478 1136-1143 NN denotes diagram
T21479 1144-1146 IN denotes of
T21480 1147-1150 DT denotes the
T21481 1151-1166 JJ denotes transcriptional
T21482 1167-1174 NN denotes network
T21483 1175-1184 VB denotes involving
T21484 1185-1190 NN denotes Runx3
T21485 1191-1194 CC denotes and
T21486 1195-1200 NN denotes T-box
T21487 1201-1208 NN denotes factors
T21488 1210-1215 NN denotes T-bet
T21489 1216-1218 VB denotes is
T21490 1219-1226 VB denotes induced
T21491 1227-1229 IN denotes by
T21492 1230-1233 NN denotes TCR
T21493 1234-1241 NN denotes signals
T21494 1242-1245 CC denotes and
T21495 1246-1248 VB denotes is
T21496 1249-1258 JJ denotes essential
T21497 1259-1262 IN denotes for
T21498 1263-1268 JJ denotes early
T21499 1269-1274 NN denotes IFN-γ
T21500 1275-1285 NN denotes expression
T21501 1287-1292 NN denotes Runx3
T21502 1293-1295 VB denotes is
T21503 1296-1303 JJ denotes present
T21504 1304-1306 IN denotes in
T21505 1307-1312 JJ denotes naive
T21506 1313-1317 JJ denotes CD8+
T21507 1318-1319 NN denotes T
T21508 1320-1325 NN denotes cells
T21509 1326-1329 CC denotes and
T21510 1330-1339 VB denotes represses
T21511 1340-1345 NN denotes Runx1
T21512 1346-1349 CC denotes and
T21513 1350-1357 VB denotes induces
T21514 1358-1363 NN denotes Eomes
T21515 1363-1364 -COMMA- denotes ,
T21516 1365-1373 NN denotes perforin
T21517 1373-1374 -COMMA- denotes ,
T21518 1375-1383 NN denotes granzyme
T21519 1384-1385 NN denotes B
T21520 1385-1386 -COMMA- denotes ,
T21521 1387-1390 CC denotes and
T21522 1391-1396 NN denotes IFN-γ
T21523 1397-1407 NN denotes expression
T21524 1409-1414 NN denotes Eomes
T21525 1415-1418 MD denotes may
T21526 1419-1430 VB denotes participate
T21527 1431-1433 IN denotes in
T21528 1434-1444 VB denotes sustaining
T21529 1445-1449 JJ denotes late
T21530 1450-1455 NN denotes IFN-γ
T21531 1456-1466 NN denotes expression
T21532 1466-1467 -COMMA- denotes ,
T21533 1468-1475 IN denotes whereas
T21534 1476-1481 NN denotes Runx3
T21535 1482-1485 CC denotes and
T21536 1486-1491 NN denotes Eomes
T21537 1492-1493 -LRB- denotes (
T21538 1493-1496 CC denotes but
T21539 1497-1500 RB denotes not
T21540 1501-1506 NN denotes T-bet
T21541 1506-1507 -RRB- denotes )
T21542 1508-1511 MD denotes may
T21543 1512-1521 VB denotes cooperate
T21544 1522-1524 TO denotes to
T21545 1525-1533 VB denotes activate
T21546 1534-1542 NN denotes perforin
T21547 1543-1553 NN denotes expression
T21548 1555-1558 DT denotes The
T21549 1559-1565 JJ denotes dotted
T21550 1566-1570 NN denotes line
T21551 1571-1580 VB denotes indicates
T21552 1581-1584 DT denotes the
T21553 1585-1592 JJ denotes partial
T21554 1593-1599 NN denotes effect
T21555 1600-1602 IN denotes of
T21556 1603-1608 JJ denotes T-bet
T21557 1609-1619 NN denotes deficiency
T21558 1620-1622 IN denotes on
T21559 1623-1627 NN denotes Gzmb
T21560 1628-1632 NN denotes mRNA
T21561 1633-1636 CC denotes but
T21562 1637-1640 RB denotes not
T21563 1641-1649 NN denotes granzyme
T21564 1650-1651 NN denotes B
T21565 1652-1659 NN denotes protein
T21566 1660-1670 NN denotes expression
R16331 T21280 T21281 arg1Of Runx3,controls
R16332 T21282 T21281 arg2Of Eomes,controls
R16333 T21282 T21283 arg1Of Eomes,","
R16334 T21284 T21285 arg1Of perforin,","
R16335 T21285 T21289 arg1Of ",",and
R16336 T21287 T21285 arg2Of B,","
R16337 T21287 T21286 arg1Of B,granzyme
R16338 T21289 T21283 arg2Of and,","
R16339 T21289 T21288 arg1Of and,","
R16340 T21289 T21292 arg1Of and,in
R16341 T21291 T21289 arg2Of expression,and
R16342 T21291 T21290 arg1Of expression,IFN-γ
R16343 T21294 T21292 arg2Of CTLs,in
R16344 T21294 T21293 arg1Of CTLs,effector
R16345 T21295 T21296 arg1Of Runx3+/+,or
R16346 T21297 T21296 arg2Of Runx3−/−,or
R16347 T21300 T21295 arg1Of cells,Runx3+/+
R16348 T21300 T21297 arg1Of cells,Runx3−/−
R16349 T21300 T21298 arg1Of cells,CD8+
R16350 T21300 T21299 arg1Of cells,T
R16351 T21300 T21301 arg1Of cells,were
R16352 T21300 T21302 arg2Of cells,activated
R16353 T21300 T21304 arg2Of cells,transduced
R16354 T21302 T21303 arg1Of activated,and
R16355 T21303 T21301 arg2Of and,were
R16356 T21304 T21303 arg2Of transduced,and
R16357 T21304 T21305 arg1Of transduced,with
R16358 T21306 T21305 arg2Of retroviruses,with
R16359 T21306 T21307 arg1Of retroviruses,bearing
R16360 T21306 T21317 arg1Of retroviruses,encoding
R16361 T21307 T21315 arg1Of bearing,or
R16362 T21311 T21307 arg2Of cassette,bearing
R16363 T21311 T21308 arg1Of cassette,an
R16364 T21311 T21309 arg1Of cassette,empty
R16365 T21311 T21310 arg1Of cassette,IRES-GFP
R16366 T21311 T21312 arg1Of cassette,(
R16367 T21313 T21312 arg2Of GFP,(
R16368 T21314 T21312 arg3Of ),(
R16369 T21317 T21315 arg2Of encoding,or
R16370 T21317 T21316 arg1Of encoding,also
R16371 T21318 T21319 arg1Of Eomes-VP16,(
R16372 T21318 T21322 arg1Of Eomes-VP16,or
R16373 T21320 T21319 arg2Of Eo-VP16,(
R16374 T21321 T21319 arg3Of ),(
R16375 T21322 T21317 arg2Of or,encoding
R16376 T21323 T21322 arg2Of Myc-Runx3,or
R16377 T21323 T21324 arg1Of Myc-Runx3,(
R16378 T21325 T21324 arg2Of Runx3,(
R16379 T21326 T21324 arg3Of ),(
R16380 T21328 T21327 arg1Of frequency,The
R16381 T21328 T21329 arg1Of frequency,of
R16382 T21328 T21332 arg1Of frequency,in
R16383 T21328 T21335 arg1Of frequency,was
R16384 T21328 T21336 arg1Of frequency,equivalent
R16385 T21331 T21329 arg2Of cells,of
R16386 T21331 T21330 arg2Of cells,transduced
R16387 T21334 T21332 arg2Of cultures,in
R16388 T21334 T21333 arg1Of cultures,the
R16389 T21336 T21335 arg2Of equivalent,was
R16390 T21336 T21337 arg1Of equivalent,for
R16391 T21339 T21337 arg2Of constructs,for
R16392 T21339 T21338 arg1Of constructs,all
R16393 T21339 T21340 arg1Of constructs,(
R16394 T21341 T21342 arg1Of ∼75–90,%
R16395 T21344 T21340 arg2Of cells,(
R16396 T21344 T21341 arg1Of cells,∼75–90
R16397 T21344 T21343 arg1Of cells,GFP+
R16398 T21344 T21345 arg1Of cells,;
R16399 T21344 T21347 arg2Of cells,depicted
R16400 T21347 T21346 arg1Of depicted,not
R16401 T21348 T21340 arg3Of ),(
R16402 T21350 T21349 arg2Of (,.
R16403 T21351 T21349 arg3Of A,.
R16404 T21353 T21349 arg1Of in express,.
R16405 T21353 T21352 arg1Of in express,) Prote
R16406 T21353 T21354 arg1Of in express,io
R16407 T21353 T21361 arg1Of in express,(da
R16408 T21353 T21362 arg2Of in express,y 6) was
R16409 T21356 T21354 arg2Of -cell ex,io
R16410 T21356 T21355 arg1Of -cell ex,n in whole
R16411 T21356 T21357 arg1Of -cell ex,t
R16412 T21358 T21357 arg2Of rac,t
R16413 T21358 T21359 arg1Of rac,t
R16414 T21360 T21357 arg3Of s,t
R16415 T21362 T21335 arg3Of y 6) was,was
R16416 T21362 T21361 arg2Of y 6) was,(da
R16417 T21364 T21362 arg1Of alyzed by immu,y 6) was
R16418 T21364 T21363 arg2Of alyzed by immu,an
R16419 T21365 T21366 arg1Of Overexpression,of
R16420 T21365 T21368 arg1Of Overexpression,can
R16421 T21365 T21370 arg1Of Overexpression,be
R16422 T21365 T21371 arg2Of Overexpression,detected
R16423 T21367 T21366 arg2Of Eomes-VP16,of
R16424 T21371 T21368 arg2Of detected,can
R16425 T21371 T21369 arg1Of detected,not
R16426 T21371 T21370 arg2Of detected,be
R16427 T21371 T21372 arg1Of detected,with
R16428 T21371 T21376 arg1Of detected,","
R16429 T21371 T21377 arg1Of detected,as
R16430 T21374 T21373 arg1Of Eomes,the
R16431 T21375 T21372 arg2Of antibody,with
R16432 T21375 T21374 arg1Of antibody,Eomes
R16433 T21380 T21378 arg1Of epitope,the
R16434 T21380 T21379 arg1Of epitope,C-terminal
R16435 T21380 T21381 arg1Of epitope,is
R16436 T21380 T21382 arg1Of epitope,within
R16437 T21381 T21408 arg1Of is,and
R16438 T21382 T21381 arg2Of within,is
R16439 T21384 T21382 arg2Of region,within
R16440 T21384 T21383 arg1Of region,the
R16441 T21384 T21385 arg1Of region,that
R16442 T21384 T21386 arg1Of region,has
R16443 T21384 T21387 arg1Of region,been
R16444 T21384 T21388 arg2Of region,replaced
R16445 T21388 T21386 arg2Of replaced,has
R16446 T21388 T21387 arg2Of replaced,been
R16447 T21388 T21389 arg1Of replaced,with
R16448 T21388 T21403 arg1Of replaced,after
R16449 T21393 T21391 arg1Of domain.,VP16
R16450 T21393 T21392 arg1Of domain.,transactivation
R16451 T21393 T21394 arg1Of domain.,(
R16452 T21395 T21394 arg2Of B,(
R16453 T21396 T21394 arg3Of ),(
R16454 T21397 T21389 arg2Of Expression,with
R16455 T21397 T21390 arg1Of Expression,the
R16456 T21397 T21393 arg1Of Expression,domain.
R16457 T21397 T21398 arg1Of Expression,of
R16458 T21400 T21399 arg1Of B,granzyme
R16459 T21400 T21401 arg1Of B,and
R16460 T21401 T21398 arg2Of and,of
R16461 T21402 T21401 arg2Of IFN-γ,and
R16462 T21404 T21403 arg2Of culture,after
R16463 T21404 T21405 arg1Of culture,for
R16464 T21407 T21405 arg2Of d,for
R16465 T21407 T21406 arg1Of d,6
R16466 T21408 T21377 arg2Of and,as
R16467 T21409 T21410 arg1Of restimulation,for
R16468 T21409 T21417 arg1Of restimulation,was
R16469 T21409 T21418 arg2Of restimulation,determined
R16470 T21412 T21410 arg2Of h,for
R16471 T21412 T21411 arg1Of h,4
R16472 T21412 T21413 arg1Of h,with
R16473 T21414 T21415 arg1Of PMA,and
R16474 T21415 T21413 arg2Of and,with
R16475 T21416 T21415 arg2Of ionomycin,and
R16476 T21418 T21408 arg2Of determined,and
R16477 T21418 T21417 arg2Of determined,was
R16478 T21421 T21418 arg1Of staining,determined
R16479 T21421 T21419 arg2Of staining,by
R16480 T21421 T21420 arg1Of staining,intracellular
R16481 T21423 T21422 arg1Of percentage,The
R16482 T21423 T21424 arg1Of percentage,of
R16483 T21423 T21428 arg1Of percentage,is
R16484 T21423 T21429 arg2Of percentage,shown
R16485 T21426 T21425 arg1Of stained,positively
R16486 T21427 T21424 arg2Of cells,of
R16487 T21427 T21426 arg1Of cells,stained
R16488 T21429 T21428 arg2Of shown,is
R16489 T21429 T21430 arg1Of shown,above
R16490 T21429 T21433 arg1Of shown,;
R16491 T21432 T21430 arg2Of gate,above
R16492 T21432 T21431 arg1Of gate,the
R16493 T21437 T21434 arg1Of intensity,the
R16494 T21437 T21435 arg1Of intensity,mean
R16495 T21437 T21436 arg1Of intensity,fluorescence
R16496 T21437 T21438 arg1Of intensity,(
R16497 T21437 T21441 arg1Of intensity,of
R16498 T21437 T21449 arg1Of intensity,is
R16499 T21437 T21450 arg2Of intensity,shown
R16500 T21439 T21438 arg2Of MFI,(
R16501 T21440 T21438 arg3Of ),(
R16502 T21444 T21441 arg2Of staining,of
R16503 T21444 T21442 arg1Of staining,granzyme
R16504 T21444 T21443 arg1Of staining,B
R16505 T21444 T21445 arg1Of staining,for
R16506 T21448 T21445 arg2Of population,for
R16507 T21448 T21446 arg1Of population,the
R16508 T21448 T21447 arg1Of population,total
R16509 T21450 T21433 arg2Of shown,;
R16510 T21450 T21449 arg2Of shown,is
R16511 T21450 T21451 arg1Of shown,below
R16512 T21453 T21451 arg2Of gate,below
R16513 T21453 T21452 arg1Of gate,the
R16514 T21457 T21454 arg1Of lines,The
R16515 T21457 T21455 arg1Of lines,vertical
R16516 T21457 T21456 arg1Of lines,gray
R16517 T21457 T21458 arg1Of lines,indicate
R16518 T21460 T21458 arg2Of MFI,indicate
R16519 T21460 T21459 arg1Of MFI,the
R16520 T21460 T21461 arg1Of MFI,for
R16521 T21464 T21461 arg2Of cells,for
R16522 T21464 T21462 arg1Of cells,WT
R16523 T21464 T21463 arg1Of cells,GFP+
R16524 T21465 T21466 arg1Of Results,are
R16525 T21465 T21467 arg1Of Results,representative
R16526 T21467 T21466 arg2Of representative,are
R16527 T21467 T21468 arg1Of representative,of
R16528 T21471 T21469 arg1Of two,at
R16529 T21471 T21470 arg1Of two,least
R16530 T21473 T21468 arg2Of experiments.,of
R16531 T21473 T21471 arg1Of experiments.,two
R16532 T21473 T21472 arg1Of experiments.,independent
R16533 T21473 T21474 arg1Of experiments.,(
R16534 T21473 T21478 arg1Of experiments.,diagram
R16535 T21475 T21474 arg2Of C,(
R16536 T21476 T21474 arg3Of ),(
R16537 T21478 T21477 arg1Of diagram,Schematic
R16538 T21478 T21479 arg1Of diagram,of
R16539 T21482 T21479 arg2Of network,of
R16540 T21482 T21480 arg1Of network,the
R16541 T21482 T21481 arg1Of network,transcriptional
R16542 T21482 T21483 arg1Of network,involving
R16543 T21484 T21485 arg1Of Runx3,and
R16544 T21485 T21483 arg2Of and,involving
R16545 T21487 T21485 arg2Of factors,and
R16546 T21487 T21486 arg1Of factors,T-box
R16547 T21488 T21489 arg1Of T-bet,is
R16548 T21488 T21490 arg2Of T-bet,induced
R16549 T21488 T21495 arg1Of T-bet,is
R16550 T21488 T21496 arg1Of T-bet,essential
R16551 T21490 T21489 arg2Of induced,is
R16552 T21490 T21494 arg1Of induced,and
R16553 T21493 T21490 arg1Of signals,induced
R16554 T21493 T21491 arg2Of signals,by
R16555 T21493 T21492 arg1Of signals,TCR
R16556 T21495 T21494 arg2Of is,and
R16557 T21496 T21495 arg2Of essential,is
R16558 T21496 T21497 arg1Of essential,for
R16559 T21500 T21497 arg2Of expression,for
R16560 T21500 T21498 arg1Of expression,early
R16561 T21500 T21499 arg1Of expression,IFN-γ
R16562 T21501 T21502 arg1Of Runx3,is
R16563 T21501 T21503 arg1Of Runx3,present
R16564 T21501 T21510 arg1Of Runx3,represses
R16565 T21501 T21513 arg1Of Runx3,induces
R16566 T21502 T21509 arg1Of is,and
R16567 T21503 T21502 arg2Of present,is
R16568 T21503 T21504 arg1Of present,in
R16569 T21508 T21504 arg2Of cells,in
R16570 T21508 T21505 arg1Of cells,naive
R16571 T21508 T21506 arg1Of cells,CD8+
R16572 T21508 T21507 arg1Of cells,T
R16573 T21510 T21512 arg1Of represses,and
R16574 T21511 T21510 arg2Of Runx1,represses
R16575 T21512 T21509 arg2Of and,and
R16576 T21513 T21512 arg2Of induces,and
R16577 T21514 T21513 arg2Of Eomes,induces
R16578 T21514 T21515 arg1Of Eomes,","
R16579 T21516 T21517 arg1Of perforin,","
R16580 T21517 T21521 arg1Of ",",and
R16581 T21519 T21517 arg2Of B,","
R16582 T21519 T21518 arg1Of B,granzyme
R16583 T21521 T21515 arg2Of and,","
R16584 T21521 T21520 arg1Of and,","
R16585 T21523 T21521 arg2Of expression,and
R16586 T21523 T21522 arg1Of expression,IFN-γ
R16587 T21524 T21525 arg1Of Eomes,may
R16588 T21524 T21526 arg1Of Eomes,participate
R16589 T21526 T21525 arg2Of participate,may
R16590 T21526 T21527 arg1Of participate,in
R16591 T21526 T21533 arg1Of participate,whereas
R16592 T21528 T21527 arg2Of sustaining,in
R16593 T21531 T21528 arg2Of expression,sustaining
R16594 T21531 T21529 arg1Of expression,late
R16595 T21531 T21530 arg1Of expression,IFN-γ
R16596 T21533 T21532 arg1Of whereas,","
R16597 T21534 T21535 arg1Of Runx3,and
R16598 T21535 T21537 arg1Of and,(
R16599 T21535 T21542 arg1Of and,may
R16600 T21535 T21543 arg1Of and,cooperate
R16601 T21535 T21545 arg1Of and,activate
R16602 T21536 T21535 arg2Of Eomes,and
R16603 T21538 T21539 arg1Of but,not
R16604 T21540 T21537 arg2Of T-bet,(
R16605 T21540 T21538 arg1Of T-bet,but
R16606 T21541 T21537 arg3Of ),(
R16607 T21543 T21533 arg2Of cooperate,whereas
R16608 T21543 T21542 arg2Of cooperate,may
R16609 T21545 T21543 arg2Of activate,cooperate
R16610 T21545 T21544 arg1Of activate,to
R16611 T21547 T21545 arg2Of expression,activate
R16612 T21547 T21546 arg1Of expression,perforin
R16613 T21550 T21548 arg1Of line,The
R16614 T21550 T21549 arg1Of line,dotted
R16615 T21550 T21551 arg1Of line,indicates
R16616 T21554 T21551 arg2Of effect,indicates
R16617 T21554 T21552 arg1Of effect,the
R16618 T21554 T21553 arg1Of effect,partial
R16619 T21554 T21555 arg1Of effect,of
R16620 T21554 T21558 arg1Of effect,on
R16621 T21557 T21555 arg2Of deficiency,of
R16622 T21557 T21556 arg1Of deficiency,T-bet
R16623 T21560 T21559 arg1Of mRNA,Gzmb
R16624 T21560 T21561 arg1Of mRNA,but
R16625 T21561 T21558 arg2Of but,on
R16626 T21566 T21561 arg2Of expression,but
R16627 T21566 T21562 arg1Of expression,not
R16628 T21566 T21563 arg1Of expression,granzyme
R16629 T21566 T21564 arg1Of expression,B
R16630 T21566 T21565 arg1Of expression,protein

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T20970 30-31 , denotes ,
T20971 32-40 NN denotes perforin
T20972 40-41 , denotes ,
T20973 42-50 NN denotes granzyme
T20974 51-52 NNP denotes B
T20975 52-53 , denotes ,
T20976 54-57 CC denotes and
T20977 58-63 NNP denotes IFN-γ
T20978 64-74 NN denotes expression
T20979 75-77 IN denotes in
T20980 78-86 NN denotes effector
T20981 87-91 NNS denotes CTLs
T20982 91-92 . denotes .
T20983 93-98 JJ denotes Runx3
T20984 98-99 NN denotes +
T20985 99-100 NN denotes /
T20986 100-101 NN denotes +
T20987 102-104 CC denotes or
T20988 105-110 JJ denotes Runx3
T20989 110-111 FW denotes −
T20990 111-112 FW denotes /
T20991 112-113 FW denotes −
T20992 114-117 FW denotes CD8
T20993 117-118 FW denotes +
T20994 119-120 FW denotes T
T20995 121-126 NNS denotes cells
T20996 127-131 VBD denotes were
T20997 132-141 VBN denotes activated
T20998 142-145 CC denotes and
T20999 146-156 VBN denotes transduced
T21000 157-161 IN denotes with
T21001 162-174 NNS denotes retroviruses
T21002 175-182 VBG denotes bearing
T21003 183-185 DT denotes an
T21004 186-191 JJ denotes empty
T21005 192-200 NNP denotes IRES-GFP
T21006 201-209 NN denotes cassette
T21007 210-211 -LRB- denotes (
T21008 211-214 NNP denotes GFP
T21009 214-215 -RRB- denotes )
T21010 216-218 CC denotes or
T21011 219-223 RB denotes also
T21012 224-232 VBG denotes encoding
T21013 233-243 NNP denotes Eomes-VP16
T21014 244-245 -LRB- denotes (
T21015 245-252 NNP denotes Eo-VP16
T21016 252-253 -RRB- denotes )
T21017 254-256 CC denotes or
T21018 257-266 JJ denotes Myc-Runx3
T21019 267-268 -LRB- denotes (
T21020 268-273 JJ denotes Runx3
T21021 273-274 -RRB- denotes )
T21022 274-275 . denotes .
T21023 276-279 DT denotes The
T21024 280-289 NN denotes frequency
T21025 290-292 IN denotes of
T21026 293-303 JJ denotes transduced
T21027 304-309 NNS denotes cells
T21028 310-312 IN denotes in
T21029 313-316 DT denotes the
T21030 317-325 NNS denotes cultures
T21031 326-329 VBD denotes was
T21032 330-340 JJ denotes equivalent
T21033 341-344 IN denotes for
T21034 345-348 DT denotes all
T21035 349-359 NNS denotes constructs
T21036 360-361 -LRB- denotes (
T21037 361-362 CD denotes ∼
T21038 362-364 CD denotes 75
T21039 365-367 CD denotes 90
T21040 367-368 NN denotes %
T21041 369-372 NNP denotes GFP
T21042 372-373 CD denotes +
T21043 374-379 NNS denotes cells
T21044 379-380 : denotes ;
T21045 381-384 RB denotes not
T21046 385-393 VBN denotes depicted
T21047 393-394 -RRB- denotes )
T21048 394-395 . denotes .
T21049 396-397 -LRB- denotes (
T21050 397-398 NNP denotes A
T21051 398-399 -RRB- denotes )
T21052 400-407 NNP denotes Protein
T21053 408-418 NN denotes expression
T21054 419-421 IN denotes in
T21055 422-432 JJ denotes whole-cell
T21056 433-441 NNS denotes extracts
T21057 442-443 -LRB- denotes (
T21058 443-446 NN denotes day
T21059 447-448 CD denotes 6
T21060 448-449 -RRB- denotes )
T21061 450-453 VBD denotes was
T21062 454-462 VBN denotes analyzed
T21063 463-465 IN denotes by
T21064 466-480 VBG denotes immunoblotting
T21065 480-481 . denotes .
T21066 482-496 NNP denotes Overexpression
T21067 497-499 IN denotes of
T21068 500-510 NNP denotes Eomes-VP16
T21069 511-514 MD denotes can
T21070 514-517 RB denotes not
T21071 518-520 VB denotes be
T21072 521-529 VBN denotes detected
T21073 530-534 IN denotes with
T21074 535-538 DT denotes the
T21075 539-544 NNP denotes Eomes
T21076 545-553 NN denotes antibody
T21077 553-554 , denotes ,
T21078 555-557 IN denotes as
T21079 558-561 DT denotes the
T21080 562-572 JJ denotes C-terminal
T21081 573-580 NN denotes epitope
T21082 581-583 VBZ denotes is
T21083 584-590 IN denotes within
T21084 591-594 DT denotes the
T21085 595-601 NN denotes region
T21086 602-606 WDT denotes that
T21087 607-610 VBZ denotes has
T21088 611-615 VBN denotes been
T21089 616-624 VBN denotes replaced
T21090 625-629 IN denotes with
T21091 630-633 DT denotes the
T21092 634-638 NNP denotes VP16
T21093 639-654 NN denotes transactivation
T21094 655-661 NN denotes domain
T21095 661-662 . denotes .
T21096 663-664 -LRB- denotes (
T21097 664-665 NNP denotes B
T21098 665-666 -RRB- denotes )
T21099 667-677 NN denotes Expression
T21100 678-680 IN denotes of
T21101 681-689 NN denotes granzyme
T21102 690-691 NNP denotes B
T21103 692-695 CC denotes and
T21104 696-701 NNP denotes IFN-γ
T21105 702-707 IN denotes after
T21106 708-715 NN denotes culture
T21107 716-719 IN denotes for
T21108 720-721 CD denotes 6
T21109 722-723 LS denotes d
T21110 724-727 CC denotes and
T21111 728-741 NN denotes restimulation
T21112 742-745 IN denotes for
T21113 746-747 CD denotes 4
T21114 748-749 NN denotes h
T21115 750-754 IN denotes with
T21116 755-758 NNP denotes PMA
T21117 759-762 CC denotes and
T21118 763-772 NN denotes ionomycin
T21119 773-776 VBD denotes was
T21120 777-787 VBN denotes determined
T21121 788-790 IN denotes by
T21122 791-804 JJ denotes intracellular
T21123 805-813 NN denotes staining
T21124 813-814 . denotes .
T21125 815-818 DT denotes The
T21126 819-829 NN denotes percentage
T21127 830-832 IN denotes of
T21128 833-843 RB denotes positively
T21129 844-851 VBN denotes stained
T21130 852-857 NNS denotes cells
T21131 858-860 VBZ denotes is
T21132 861-866 VBN denotes shown
T21133 867-872 IN denotes above
T21134 873-876 DT denotes the
T21135 877-881 NN denotes gate
T21136 881-882 : denotes ;
T21137 883-886 DT denotes the
T21138 887-891 JJ denotes mean
T21139 892-904 NN denotes fluorescence
T21140 905-914 NN denotes intensity
T21141 915-916 -LRB- denotes (
T21142 916-919 NNP denotes MFI
T21143 919-920 -RRB- denotes )
T21144 921-923 IN denotes of
T21145 924-932 NN denotes granzyme
T21146 933-934 NNP denotes B
T21147 935-943 VBG denotes staining
T21148 944-947 IN denotes for
T21149 948-951 DT denotes the
T21150 952-957 JJ denotes total
T21151 958-968 NN denotes population
T21152 969-971 VBZ denotes is
T21153 972-977 VBN denotes shown
T21154 978-983 IN denotes below
T21155 984-987 DT denotes the
T21156 988-992 NN denotes gate
T21157 992-993 . denotes .
T21158 994-997 DT denotes The
T21159 998-1006 JJ denotes vertical
T21160 1007-1011 JJ denotes gray
T21161 1012-1017 NNS denotes lines
T21162 1018-1026 VBP denotes indicate
T21163 1027-1030 DT denotes the
T21164 1031-1034 NNP denotes MFI
T21165 1035-1038 IN denotes for
T21166 1039-1041 NNP denotes WT
T21167 1042-1045 NNP denotes GFP
T21168 1045-1046 NN denotes +
T21169 1047-1052 NNS denotes cells
T21170 1052-1053 . denotes .
T21171 1054-1061 NNS denotes Results
T21172 1062-1065 VBP denotes are
T21173 1066-1080 NN denotes representative
T21174 1081-1083 IN denotes of
T21175 1084-1086 IN denotes at
T21176 1087-1092 JJS denotes least
T21177 1093-1096 CD denotes two
T21178 1097-1108 JJ denotes independent
T21179 1109-1120 NNS denotes experiments
T21180 1120-1121 . denotes .
T21181 1122-1123 -LRB- denotes (
T21182 1123-1124 $ denotes C
T21183 1124-1125 -RRB- denotes )
T21184 1126-1135 JJ denotes Schematic
T21185 1136-1143 NN denotes diagram
T21186 1144-1146 IN denotes of
T21187 1147-1150 DT denotes the
T21188 1151-1166 JJ denotes transcriptional
T21189 1167-1174 NN denotes network
T21190 1175-1184 VBG denotes involving
T21191 1185-1190 NNP denotes Runx3
T21192 1191-1194 CC denotes and
T21193 1195-1200 NNP denotes T-box
T21194 1201-1208 NNS denotes factors
T21195 1208-1209 . denotes .
T21196 1210-1215 NN denotes T-bet
T21197 1216-1218 VBZ denotes is
T21198 1219-1226 VBN denotes induced
T21199 1227-1229 IN denotes by
T21200 1230-1233 NNP denotes TCR
T21201 1234-1241 NNS denotes signals
T21202 1242-1245 CC denotes and
T21203 1246-1248 VBZ denotes is
T21204 1249-1258 JJ denotes essential
T21205 1259-1262 IN denotes for
T21206 1263-1268 JJ denotes early
T21207 1269-1274 JJ denotes IFN-γ
T21208 1275-1285 NN denotes expression
T21209 1285-1286 . denotes .
T21210 1287-1292 NN denotes Runx3
T21211 1293-1295 VBZ denotes is
T21212 1296-1303 JJ denotes present
T21213 1304-1306 IN denotes in
T21214 1307-1312 JJ denotes naive
T21215 1313-1316 NNP denotes CD8
T21216 1316-1317 CD denotes +
T21217 1318-1319 NNP denotes T
T21218 1320-1325 NNS denotes cells
T21219 1326-1329 CC denotes and
T21220 1330-1339 VBZ denotes represses
T21221 1340-1345 NNP denotes Runx1
T21222 1346-1349 CC denotes and
T21223 1350-1357 VBZ denotes induces
T21224 1358-1363 NNP denotes Eomes
T21225 1363-1364 , denotes ,
T21226 1365-1373 NN denotes perforin
T21227 1373-1374 , denotes ,
T21228 1375-1383 NN denotes granzyme
T21229 1384-1385 NNP denotes B
T21230 1385-1386 , denotes ,
T21231 1387-1390 CC denotes and
T21232 1391-1396 NNP denotes IFN-γ
T21233 1397-1407 NN denotes expression
T21234 1407-1408 . denotes .
T21235 1409-1414 NNS denotes Eomes
T21236 1415-1418 MD denotes may
T21237 1419-1430 VB denotes participate
T21238 1431-1433 IN denotes in
T21239 1434-1444 VBG denotes sustaining
T21240 1445-1449 JJ denotes late
T21241 1450-1455 JJ denotes IFN-γ
T21242 1456-1466 NN denotes expression
T21243 1466-1467 , denotes ,
T21244 1468-1475 IN denotes whereas
T21245 1476-1481 NNP denotes Runx3
T21246 1482-1485 CC denotes and
T21247 1486-1491 NNP denotes Eomes
T21248 1492-1493 -LRB- denotes (
T21249 1493-1496 CC denotes but
T21250 1497-1500 RB denotes not
T21251 1501-1506 NNP denotes T-bet
T21252 1506-1507 -RRB- denotes )
T21253 1508-1511 MD denotes may
T21254 1512-1521 VB denotes cooperate
T21255 1522-1524 TO denotes to
T21256 1525-1533 VB denotes activate
T21257 1534-1542 JJ denotes perforin
T21258 1543-1553 NN denotes expression
T21259 1553-1554 . denotes .
T21260 1555-1558 DT denotes The
T21261 1559-1565 JJ denotes dotted
T20967 10-15 JJ denotes Runx3
T20968 16-24 NNS denotes controls
T20969 25-30 NNP denotes Eomes
T21262 1566-1570 NN denotes line
T21263 1571-1580 VBZ denotes indicates
T21264 1581-1584 DT denotes the
T21265 1585-1592 JJ denotes partial
T21266 1593-1599 NN denotes effect
T21267 1600-1602 IN denotes of
T21268 1603-1608 NN denotes T-bet
T21269 1609-1619 NN denotes deficiency
T21270 1620-1622 IN denotes on
T21271 1623-1627 NNP denotes Gzmb
T21272 1628-1632 NNP denotes mRNA
T21273 1633-1636 CC denotes but
T21274 1637-1640 RB denotes not
T21275 1641-1649 VB denotes granzyme
T21276 1650-1651 NNP denotes B
T21277 1652-1659 NN denotes protein
T21278 1660-1670 NN denotes expression
T21279 1670-1671 . denotes .
R16018 T20967 T20968 amod Runx3,controls
R16019 T20968 T20968 ROOT controls,controls
R16020 T20969 T20968 appos Eomes,controls
R16021 T20970 T20969 punct ",",Eomes
R16022 T20971 T20969 appos perforin,Eomes
R16023 T20972 T20969 punct ",",Eomes
R16024 T20973 T20974 compound granzyme,B
R16025 T20974 T20969 conj B,Eomes
R16026 T20975 T20969 punct ",",Eomes
R16027 T20976 T20969 cc and,Eomes
R16028 T20977 T20978 compound IFN-γ,expression
R16029 T20978 T20969 conj expression,Eomes
R16030 T20979 T20978 prep in,expression
R16031 T20980 T20981 compound effector,CTLs
R16032 T20981 T20979 pobj CTLs,in
R16033 T20982 T20968 punct .,controls
R16034 T20983 T20986 amod Runx3,+
R16035 T20984 T20986 compound +,+
R16036 T20985 T20986 compound /,+
R16037 T20986 T20997 nsubjpass +,activated
R16038 T20987 T20986 cc or,+
R16039 T20988 T20995 amod Runx3,cells
R16040 T20989 T20995 nmod −,cells
R16041 T20990 T20995 nmod /,cells
R16042 T20991 T20995 nmod −,cells
R16043 T20992 T20995 nmod CD8,cells
R16044 T20993 T20995 nmod +,cells
R16045 T20994 T20995 compound T,cells
R16046 T20995 T20986 conj cells,+
R16047 T20996 T20997 auxpass were,activated
R16048 T20997 T20997 ROOT activated,activated
R16049 T20998 T20997 cc and,activated
R16050 T20999 T20997 conj transduced,activated
R16051 T21000 T20999 prep with,transduced
R16052 T21001 T21000 pobj retroviruses,with
R16053 T21002 T21001 acl bearing,retroviruses
R16054 T21003 T21006 det an,cassette
R16055 T21004 T21006 amod empty,cassette
R16056 T21005 T21006 compound IRES-GFP,cassette
R16057 T21006 T21002 dobj cassette,bearing
R16058 T21007 T21006 punct (,cassette
R16059 T21008 T21006 appos GFP,cassette
R16060 T21009 T21008 punct ),GFP
R16061 T21010 T21006 cc or,cassette
R16062 T21011 T21012 advmod also,encoding
R16063 T21012 T20997 advcl encoding,activated
R16064 T21013 T21012 dobj Eomes-VP16,encoding
R16065 T21014 T21015 punct (,Eo-VP16
R16066 T21015 T21013 appos Eo-VP16,Eomes-VP16
R16067 T21016 T21015 punct ),Eo-VP16
R16068 T21017 T21013 cc or,Eomes-VP16
R16069 T21018 T21013 conj Myc-Runx3,Eomes-VP16
R16070 T21019 T21020 punct (,Runx3
R16071 T21020 T21018 appos Runx3,Myc-Runx3
R16072 T21021 T21020 punct ),Runx3
R16073 T21022 T20997 punct .,activated
R16074 T21023 T21024 det The,frequency
R16075 T21024 T21031 nsubj frequency,was
R16076 T21025 T21024 prep of,frequency
R16077 T21026 T21027 amod transduced,cells
R16078 T21027 T21025 pobj cells,of
R16079 T21028 T21024 prep in,frequency
R16080 T21029 T21030 det the,cultures
R16081 T21030 T21028 pobj cultures,in
R16082 T21031 T21031 ROOT was,was
R16083 T21032 T21031 acomp equivalent,was
R16084 T21033 T21032 prep for,equivalent
R16085 T21034 T21035 det all,constructs
R16086 T21035 T21033 pobj constructs,for
R16087 T21036 T21035 punct (,constructs
R16088 T21037 T21038 nmod ∼,75
R16089 T21038 T21035 appos 75,constructs
R16090 T21039 T21040 nummod 90,%
R16091 T21040 T21043 compound %,cells
R16092 T21041 T21043 compound GFP,cells
R16093 T21042 T21043 nummod +,cells
R16094 T21043 T21035 appos cells,constructs
R16095 T21044 T21046 punct ;,depicted
R16096 T21045 T21046 neg not,depicted
R16097 T21046 T21031 conj depicted,was
R16098 T21047 T21046 punct ),depicted
R16099 T21048 T21031 punct .,was
R16100 T21049 T21062 punct (,analyzed
R16101 T21050 T21053 nmod A,expression
R16102 T21051 T21050 punct ),A
R16103 T21052 T21053 compound Protein,expression
R16104 T21053 T21062 nsubjpass expression,analyzed
R16105 T21054 T21053 prep in,expression
R16106 T21055 T21056 amod whole-cell,extracts
R16107 T21056 T21054 pobj extracts,in
R16108 T21057 T21058 punct (,day
R16109 T21058 T21053 appos day,expression
R16110 T21059 T21058 nummod 6,day
R16111 T21060 T21053 punct ),expression
R16112 T21061 T21062 auxpass was,analyzed
R16113 T21062 T21062 ROOT analyzed,analyzed
R16114 T21063 T21062 agent by,analyzed
R16115 T21064 T21063 pcomp immunoblotting,by
R16116 T21065 T21062 punct .,analyzed
R16117 T21066 T21072 nsubjpass Overexpression,detected
R16118 T21067 T21066 prep of,Overexpression
R16119 T21068 T21067 pobj Eomes-VP16,of
R16120 T21069 T21072 aux can,detected
R16121 T21070 T21072 neg not,detected
R16122 T21071 T21072 auxpass be,detected
R16123 T21072 T21072 ROOT detected,detected
R16124 T21073 T21072 prep with,detected
R16125 T21074 T21076 det the,antibody
R16126 T21075 T21076 compound Eomes,antibody
R16127 T21076 T21073 pobj antibody,with
R16128 T21077 T21072 punct ",",detected
R16129 T21078 T21082 mark as,is
R16130 T21079 T21081 det the,epitope
R16131 T21080 T21081 amod C-terminal,epitope
R16132 T21081 T21082 nsubj epitope,is
R16133 T21082 T21072 advcl is,detected
R16134 T21083 T21082 prep within,is
R16135 T21084 T21085 det the,region
R16136 T21085 T21083 pobj region,within
R16137 T21086 T21089 nsubjpass that,replaced
R16138 T21087 T21089 aux has,replaced
R16139 T21088 T21089 auxpass been,replaced
R16140 T21089 T21085 relcl replaced,region
R16141 T21090 T21089 prep with,replaced
R16142 T21091 T21094 det the,domain
R16143 T21092 T21094 compound VP16,domain
R16144 T21093 T21094 compound transactivation,domain
R16145 T21094 T21090 pobj domain,with
R16146 T21095 T21072 punct .,detected
R16147 T21096 T21099 punct (,Expression
R16148 T21097 T21099 nmod B,Expression
R16149 T21098 T21097 punct ),B
R16150 T21099 T21099 ROOT Expression,Expression
R16151 T21100 T21099 prep of,Expression
R16152 T21101 T21102 compound granzyme,B
R16153 T21102 T21100 pobj B,of
R16154 T21103 T21102 cc and,B
R16155 T21104 T21102 conj IFN-γ,B
R16156 T21105 T21099 prep after,Expression
R16157 T21106 T21105 pobj culture,after
R16158 T21107 T21099 prep for,Expression
R16159 T21108 T21107 pobj 6,for
R16160 T21109 T21120 nsubjpass d,determined
R16161 T21110 T21109 cc and,d
R16162 T21111 T21109 conj restimulation,d
R16163 T21112 T21111 prep for,restimulation
R16164 T21113 T21114 nummod 4,h
R16165 T21114 T21112 pobj h,for
R16166 T21115 T21114 prep with,h
R16167 T21116 T21115 pobj PMA,with
R16168 T21117 T21116 cc and,PMA
R16169 T21118 T21116 conj ionomycin,PMA
R16170 T21119 T21120 auxpass was,determined
R16171 T21120 T21120 ROOT determined,determined
R16172 T21121 T21120 agent by,determined
R16173 T21122 T21123 amod intracellular,staining
R16174 T21123 T21121 pobj staining,by
R16175 T21124 T21120 punct .,determined
R16176 T21125 T21126 det The,percentage
R16177 T21126 T21132 nsubjpass percentage,shown
R16178 T21127 T21126 prep of,percentage
R16179 T21128 T21129 advmod positively,stained
R16180 T21129 T21130 amod stained,cells
R16181 T21130 T21127 pobj cells,of
R16182 T21131 T21132 auxpass is,shown
R16183 T21132 T21153 ccomp shown,shown
R16184 T21133 T21132 prep above,shown
R16185 T21134 T21135 det the,gate
R16186 T21135 T21133 pobj gate,above
R16187 T21136 T21153 punct ;,shown
R16188 T21137 T21140 det the,intensity
R16189 T21138 T21140 amod mean,intensity
R16190 T21139 T21140 compound fluorescence,intensity
R16191 T21140 T21153 nsubjpass intensity,shown
R16192 T21141 T21142 punct (,MFI
R16193 T21142 T21140 appos MFI,intensity
R16194 T21143 T21142 punct ),MFI
R16195 T21144 T21142 prep of,MFI
R16196 T21145 T21146 compound granzyme,B
R16197 T21146 T21144 pobj B,of
R16198 T21147 T21140 conj staining,intensity
R16199 T21148 T21147 prep for,staining
R16200 T21149 T21151 det the,population
R16201 T21150 T21151 amod total,population
R16202 T21151 T21148 pobj population,for
R16203 T21152 T21153 auxpass is,shown
R16204 T21153 T21153 ROOT shown,shown
R16205 T21154 T21153 prep below,shown
R16206 T21155 T21156 det the,gate
R16207 T21156 T21154 pobj gate,below
R16208 T21157 T21153 punct .,shown
R16209 T21158 T21161 det The,lines
R16210 T21159 T21161 amod vertical,lines
R16211 T21160 T21161 amod gray,lines
R16212 T21161 T21162 nsubj lines,indicate
R16213 T21162 T21162 ROOT indicate,indicate
R16214 T21163 T21164 det the,MFI
R16215 T21164 T21162 dobj MFI,indicate
R16216 T21165 T21162 prep for,indicate
R16217 T21166 T21167 compound WT,GFP
R16218 T21167 T21169 compound GFP,cells
R16219 T21168 T21169 compound +,cells
R16220 T21169 T21165 pobj cells,for
R16221 T21170 T21162 punct .,indicate
R16222 T21171 T21172 nsubj Results,are
R16223 T21172 T21172 ROOT are,are
R16224 T21173 T21172 attr representative,are
R16225 T21174 T21173 prep of,representative
R16226 T21175 T21176 advmod at,least
R16227 T21176 T21177 advmod least,two
R16228 T21177 T21179 nummod two,experiments
R16229 T21178 T21179 amod independent,experiments
R16230 T21179 T21174 pobj experiments,of
R16231 T21180 T21172 punct .,are
R16232 T21181 T21182 punct (,C
R16233 T21182 T21185 nmod C,diagram
R16234 T21183 T21182 punct ),C
R16235 T21184 T21185 amod Schematic,diagram
R16236 T21185 T21185 ROOT diagram,diagram
R16237 T21186 T21185 prep of,diagram
R16238 T21187 T21189 det the,network
R16239 T21188 T21189 amod transcriptional,network
R16240 T21189 T21186 pobj network,of
R16241 T21190 T21189 acl involving,network
R16242 T21191 T21190 dobj Runx3,involving
R16243 T21192 T21191 cc and,Runx3
R16244 T21193 T21191 conj T-box,Runx3
R16245 T21194 T21186 pobj factors,of
R16246 T21195 T21185 punct .,diagram
R16247 T21196 T21198 nsubjpass T-bet,induced
R16248 T21197 T21198 auxpass is,induced
R16249 T21198 T21198 ROOT induced,induced
R16250 T21199 T21198 agent by,induced
R16251 T21200 T21201 compound TCR,signals
R16252 T21201 T21199 pobj signals,by
R16253 T21202 T21198 cc and,induced
R16254 T21203 T21198 conj is,induced
R16255 T21204 T21203 acomp essential,is
R16256 T21205 T21204 prep for,essential
R16257 T21206 T21208 amod early,expression
R16258 T21207 T21208 amod IFN-γ,expression
R16259 T21208 T21205 pobj expression,for
R16260 T21209 T21203 punct .,is
R16261 T21210 T21211 nsubj Runx3,is
R16262 T21211 T21211 ROOT is,is
R16263 T21212 T21211 acomp present,is
R16264 T21213 T21212 prep in,present
R16265 T21214 T21218 amod naive,cells
R16266 T21215 T21218 nmod CD8,cells
R16267 T21216 T21218 nummod +,cells
R16268 T21217 T21218 compound T,cells
R16269 T21218 T21213 pobj cells,in
R16270 T21219 T21211 cc and,is
R16271 T21220 T21211 conj represses,is
R16272 T21221 T21220 dobj Runx1,represses
R16273 T21222 T21220 cc and,represses
R16274 T21223 T21220 conj induces,represses
R16275 T21224 T21223 dobj Eomes,induces
R16276 T21225 T21224 punct ",",Eomes
R16277 T21226 T21224 appos perforin,Eomes
R16278 T21227 T21224 punct ",",Eomes
R16279 T21228 T21229 compound granzyme,B
R16280 T21229 T21224 conj B,Eomes
R16281 T21230 T21220 punct ",",represses
R16282 T21231 T21220 cc and,represses
R16283 T21232 T21233 compound IFN-γ,expression
R16284 T21233 T21220 conj expression,represses
R16285 T21234 T21211 punct .,is
R16286 T21235 T21237 nsubj Eomes,participate
R16287 T21236 T21237 aux may,participate
R16288 T21237 T21237 ROOT participate,participate
R16289 T21238 T21237 prep in,participate
R16290 T21239 T21238 pcomp sustaining,in
R16291 T21240 T21242 amod late,expression
R16292 T21241 T21242 amod IFN-γ,expression
R16293 T21242 T21239 dobj expression,sustaining
R16294 T21243 T21237 punct ",",participate
R16295 T21244 T21254 mark whereas,cooperate
R16324 T21273 T21263 cc but,indicates
R16325 T21274 T21275 neg not,granzyme
R16326 T21275 T21263 conj granzyme,indicates
R16327 T21276 T21278 compound B,expression
R16328 T21277 T21278 compound protein,expression
R16329 T21278 T21275 dobj expression,granzyme
R16330 T21279 T21263 punct .,indicates
R16296 T21245 T21254 nsubj Runx3,cooperate
R16297 T21246 T21245 cc and,Runx3
R16298 T21247 T21245 conj Eomes,Runx3
R16299 T21248 T21251 punct (,T-bet
R16300 T21249 T21251 cc but,T-bet
R16301 T21250 T21251 neg not,T-bet
R16302 T21251 T21245 conj T-bet,Runx3
R16303 T21252 T21251 punct ),T-bet
R16304 T21253 T21254 aux may,cooperate
R16305 T21254 T21237 advcl cooperate,participate
R16306 T21255 T21256 aux to,activate
R16307 T21256 T21254 advcl activate,cooperate
R16308 T21257 T21258 amod perforin,expression
R16309 T21258 T21256 dobj expression,activate
R16310 T21259 T21237 punct .,participate
R16311 T21260 T21262 det The,line
R16312 T21261 T21262 amod dotted,line
R16313 T21262 T21263 nsubj line,indicates
R16314 T21263 T21263 ROOT indicates,indicates
R16315 T21264 T21266 det the,effect
R16316 T21265 T21266 amod partial,effect
R16317 T21266 T21263 dobj effect,indicates
R16318 T21267 T21266 prep of,effect
R16319 T21268 T21269 amod T-bet,deficiency
R16320 T21269 T21267 pobj deficiency,of
R16321 T21270 T21269 prep on,deficiency
R16322 T21271 T21272 compound Gzmb,mRNA
R16323 T21272 T21270 pobj mRNA,on

GO-BP

Id Subject Object Predicate Lexical cue
T20963 639-654 http://purl.obolibrary.org/obo/GO_2000144 denotes transactivation
T20964 1151-1166 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T20965 1230-1233 http://purl.obolibrary.org/obo/GO_0006283 denotes TCR
T20966 1234-1241 http://purl.obolibrary.org/obo/GO_0023052 denotes signals

GO-MF

Id Subject Object Predicate Lexical cue
T21621 545-553 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody

GO-CC

Id Subject Object Predicate Lexical cue
T21622 121-126 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T21623 304-309 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T21624 374-379 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T21625 852-857 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T21626 1047-1052 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T21627 1320-1325 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T21628 545-553 http://purl.obolibrary.org/obo/GO_0019815 denotes antibody
T21629 545-553 http://purl.obolibrary.org/obo/GO_0042571 denotes antibody
T21630 791-804 http://purl.obolibrary.org/obo/GO_0005622 denotes intracellular
T21631 1230-1233 http://purl.obolibrary.org/obo/GO_0042101 denotes TCR

sentences

Id Subject Object Predicate Lexical cue
T20952 10-92 Sentence denotes Runx3 controls Eomes, perforin, granzyme B, and IFN-γ expression in effector CTLs.
T20953 93-275 Sentence denotes Runx3+/+ or Runx3−/− CD8+ T cells were activated and transduced with retroviruses bearing an empty IRES-GFP cassette (GFP) or also encoding Eomes-VP16 (Eo-VP16) or Myc-Runx3 (Runx3).
T20954 276-481 Sentence denotes The frequency of transduced cells in the cultures was equivalent for all constructs (∼75–90% GFP+ cells; not depicted). (A) Protein expression in whole-cell extracts (day 6) was analyzed by immunoblotting.
T20955 482-814 Sentence denotes Overexpression of Eomes-VP16 cannot be detected with the Eomes antibody, as the C-terminal epitope is within the region that has been replaced with the VP16 transactivation domain. (B) Expression of granzyme B and IFN-γ after culture for 6 d and restimulation for 4 h with PMA and ionomycin was determined by intracellular staining.
T20956 815-993 Sentence denotes The percentage of positively stained cells is shown above the gate; the mean fluorescence intensity (MFI) of granzyme B staining for the total population is shown below the gate.
T20957 994-1053 Sentence denotes The vertical gray lines indicate the MFI for WT GFP+ cells.
T20958 1054-1209 Sentence denotes Results are representative of at least two independent experiments. (C) Schematic diagram of the transcriptional network involving Runx3 and T-box factors.
T20959 1210-1286 Sentence denotes T-bet is induced by TCR signals and is essential for early IFN-γ expression.
T20960 1287-1408 Sentence denotes Runx3 is present in naive CD8+ T cells and represses Runx1 and induces Eomes, perforin, granzyme B, and IFN-γ expression.
T20961 1409-1554 Sentence denotes Eomes may participate in sustaining late IFN-γ expression, whereas Runx3 and Eomes (but not T-bet) may cooperate to activate perforin expression.
T20962 1555-1671 Sentence denotes The dotted line indicates the partial effect of T-bet deficiency on Gzmb mRNA but not granzyme B protein expression.
T111 0-9 Sentence denotes Figure 4.
T112 10-92 Sentence denotes Runx3 controls Eomes, perforin, granzyme B, and IFN-γ expression in effector CTLs.
T113 93-275 Sentence denotes Runx3+/+ or Runx3−/− CD8+ T cells were activated and transduced with retroviruses bearing an empty IRES-GFP cassette (GFP) or also encoding Eomes-VP16 (Eo-VP16) or Myc-Runx3 (Runx3).
T114 276-481 Sentence denotes The frequency of transduced cells in the cultures was equivalent for all constructs (∼75–90% GFP+ cells; not depicted). (A) Protein expression in whole-cell extracts (day 6) was analyzed by immunoblotting.
T115 482-814 Sentence denotes Overexpression of Eomes-VP16 cannot be detected with the Eomes antibody, as the C-terminal epitope is within the region that has been replaced with the VP16 transactivation domain. (B) Expression of granzyme B and IFN-γ after culture for 6 d and restimulation for 4 h with PMA and ionomycin was determined by intracellular staining.
T116 815-993 Sentence denotes The percentage of positively stained cells is shown above the gate; the mean fluorescence intensity (MFI) of granzyme B staining for the total population is shown below the gate.
T117 994-1053 Sentence denotes The vertical gray lines indicate the MFI for WT GFP+ cells.
T118 1054-1209 Sentence denotes Results are representative of at least two independent experiments. (C) Schematic diagram of the transcriptional network involving Runx3 and T-box factors.
T119 1210-1286 Sentence denotes T-bet is induced by TCR signals and is essential for early IFN-γ expression.
T120 1287-1408 Sentence denotes Runx3 is present in naive CD8+ T cells and represses Runx1 and induces Eomes, perforin, granzyme B, and IFN-γ expression.
T121 1409-1554 Sentence denotes Eomes may participate in sustaining late IFN-γ expression, whereas Runx3 and Eomes (but not T-bet) may cooperate to activate perforin expression.

events-check-again

Id Subject Object Predicate Lexical cue Negation Speculation
T21972 10-15 Protein denotes Runx3
T21973 16-24 Regulation denotes controls
T21974 16-24 Regulation denotes controls
T21975 16-24 Regulation denotes controls
T21976 16-24 Regulation denotes controls
T21977 25-30 Protein denotes Eomes
T21978 32-40 Protein denotes perforin
T21979 42-52 Protein denotes granzyme B
T21980 58-63 Protein denotes IFN-γ
T21981 64-74 Gene_expression denotes expression
T21982 64-74 Gene_expression denotes expression
T21983 64-74 Gene_expression denotes expression
T21984 64-74 Gene_expression denotes expression
T21985 93-98 Protein denotes Runx3
T21986 105-110 Protein denotes Runx3
T21987 114-117 Protein denotes CD8
T21988 197-200 Protein denotes GFP
T21989 233-243 Protein denotes Eomes-VP16
T21990 245-252 Protein denotes Eo-VP16
T21991 257-260 Protein denotes Myc
T21992 261-266 Protein denotes Runx3
T21993 268-273 Protein denotes Runx3
T21994 482-496 Positive_regulation denotes Overexpression
T21995 500-510 Protein denotes Eomes-VP16
T21996 539-544 Protein denotes Eomes
T21997 634-638 Protein denotes VP16
T21998 667-677 Gene_expression denotes Expression true
T21999 667-677 Gene_expression denotes Expression true
T22000 681-691 Protein denotes granzyme B
T22001 696-701 Protein denotes IFN-γ
T22002 924-934 Protein denotes granzyme B
T22003 935-943 Gene_expression denotes staining true
T22004 1042-1045 Protein denotes GFP
T22005 1185-1190 Protein denotes Runx3
T22006 1210-1215 Protein denotes T-bet
T22007 1219-1226 Positive_regulation denotes induced
T22008 1249-1258 Positive_regulation denotes essential
T22009 1269-1274 Protein denotes IFN-γ
T22010 1275-1285 Gene_expression denotes expression
T22011 1287-1292 Protein denotes Runx3
T22012 1296-1303 Gene_expression denotes present
T22013 1313-1316 Protein denotes CD8
T22014 1330-1339 Negative_regulation denotes represses
T22015 1340-1345 Protein denotes Runx1
T22016 1350-1357 Positive_regulation denotes induces
T22017 1350-1357 Positive_regulation denotes induces
T22018 1350-1357 Positive_regulation denotes induces
T22019 1350-1357 Positive_regulation denotes induces
T22020 1358-1363 Protein denotes Eomes
T22021 1365-1373 Protein denotes perforin
T22022 1375-1385 Protein denotes granzyme B
T22023 1391-1396 Protein denotes IFN-γ
T22024 1397-1407 Gene_expression denotes expression
T22025 1397-1407 Gene_expression denotes expression
T22026 1397-1407 Gene_expression denotes expression
T22027 1397-1407 Gene_expression denotes expression
T22028 1409-1414 Protein denotes Eomes
T22029 1419-1430 Regulation denotes participate true
T22030 1450-1455 Protein denotes IFN-γ
T22031 1456-1466 Gene_expression denotes expression
T22032 1476-1481 Protein denotes Runx3
T22033 1486-1491 Protein denotes Eomes
T22034 1501-1506 Protein denotes T-bet
T22035 1525-1533 Positive_regulation denotes activate true
T22036 1525-1533 Positive_regulation denotes activate true
T22037 1525-1533 Positive_regulation denotes activate true true
T22038 1534-1542 Protein denotes perforin
T22039 1543-1553 Gene_expression denotes expression
T22040 1593-1599 Regulation denotes effect
T22041 1593-1599 Regulation denotes effect
T22042 1603-1608 Protein denotes T-bet
T22043 1609-1619 Negative_regulation denotes deficiency
T22044 1623-1627 Protein denotes Gzmb
T22045 1641-1651 Protein denotes granzyme B
T22046 1660-1670 Gene_expression denotes expression
T22047 1660-1670 Gene_expression denotes expression true
R16849 T21972 T21976 causeOf Runx3,controls
R16850 T21972 T21975 causeOf Runx3,controls
R16851 T21972 T21974 causeOf Runx3,controls
R16852 T21972 T21973 causeOf Runx3,controls
R16853 T21977 T21982 themeOf Eomes,expression
R16854 T21978 T21983 themeOf perforin,expression
R16855 T21979 T21981 themeOf granzyme B,expression
R16856 T21980 T21984 themeOf IFN-γ,expression
R16857 T21981 T21973 themeOf expression,controls
R16858 T21982 T21975 themeOf expression,controls
R16859 T21983 T21974 themeOf expression,controls
R16860 T21984 T21976 themeOf expression,controls
R16861 T21990 T21989 equivalentTo Eo-VP16,Eomes-VP16
R16862 T21995 T21994 themeOf Eomes-VP16,Overexpression
R16863 T22000 T21999 themeOf granzyme B,Expression
R16864 T22001 T21998 themeOf IFN-γ,Expression
R16865 T22002 T22003 themeOf granzyme B,staining
R16866 T22006 T22007 themeOf T-bet,induced
R16867 T22006 T22008 causeOf T-bet,essential
R16868 T22009 T22010 themeOf IFN-γ,expression
R16869 T22010 T22008 themeOf expression,essential
R16870 T22011 T22012 themeOf Runx3,present
R16871 T22011 T22014 causeOf Runx3,represses
R16872 T22011 T22019 causeOf Runx3,induces
R16873 T22011 T22017 causeOf Runx3,induces
R16874 T22011 T22018 causeOf Runx3,induces
R16875 T22011 T22016 causeOf Runx3,induces
R16876 T22015 T22014 themeOf Runx1,represses
R16877 T22020 T22026 themeOf Eomes,expression
R16878 T22021 T22027 themeOf perforin,expression
R16879 T22022 T22024 themeOf granzyme B,expression
R16880 T22023 T22025 themeOf IFN-γ,expression
R16881 T22024 T22018 themeOf expression,induces
R16882 T22025 T22016 themeOf expression,induces
R16883 T22026 T22019 themeOf expression,induces
R16884 T22027 T22017 themeOf expression,induces
R16885 T22028 T22029 causeOf Eomes,participate
R16886 T22030 T22031 themeOf IFN-γ,expression
R16887 T22031 T22029 themeOf expression,participate
R16888 T22032 T22036 causeOf Runx3,activate
R16889 T22033 T22035 causeOf Eomes,activate
R16890 T22034 T22037 causeOf T-bet,activate
R16891 T22038 T22039 themeOf perforin,expression
R16892 T22039 T22036 themeOf expression,activate
R16893 T22039 T22035 themeOf expression,activate
R16894 T22039 T22037 themeOf expression,activate
R16895 T22042 T22043 themeOf T-bet,deficiency
R16896 T22043 T22040 causeOf deficiency,effect
R16897 T22043 T22041 causeOf deficiency,effect
R16898 T22044 T22046 themeOf Gzmb,expression
R16899 T22045 T22047 themeOf granzyme B,expression
R16900 T22046 T22040 themeOf expression,effect
R16901 T22047 T22041 themeOf expression,effect

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T22048 10-15 Protein denotes Runx3
T22049 32-40 Protein denotes perforin
T22050 42-52 Protein denotes granzyme B
T22051 58-63 Protein denotes IFN-γ
T22052 16-24 Regulation denotes controls
T22053 16-24 Regulation denotes controls
T22054 64-74 Gene_expression denotes expression
T22055 64-74 Gene_expression denotes expression
T22056 64-74 Gene_expression denotes expression
T22057 16-24 Regulation denotes controls
T22058 16-24 Regulation denotes controls
T22059 16-24 Regulation denotes controls
T22060 93-98 Protein denotes Runx3
T22061 105-110 Protein denotes Runx3
T22062 114-117 Protein denotes CD8
T22063 192-209 Protein denotes IRES-GFP cassette
T22064 211-214 Protein denotes GFP
T22065 233-243 Protein denotes Eomes-VP16
T22066 245-247 Protein denotes Eo
T22067 248-252 Protein denotes VP16
T22068 257-260 Protein denotes Myc
T22069 261-266 Protein denotes Runx3
T22070 268-273 Protein denotes Runx3
T22071 500-505 Protein denotes Eomes
T22072 506-510 Protein denotes VP16
T22073 634-661 Protein denotes VP16 transactivation domain
T22074 482-496 Positive_regulation denotes Overexpression
T22075 482-496 Positive_regulation denotes Overexpression
T22076 681-691 Protein denotes granzyme B
T22077 696-701 Protein denotes IFN-γ
T22078 667-677 Gene_expression denotes Expression
T22079 667-677 Gene_expression denotes Expression
T22080 924-934 Protein denotes granzyme B
T22081 935-943 Gene_expression denotes staining
T22082 1039-1045 Protein denotes WT GFP
T22083 1185-1190 Protein denotes Runx3
T22084 1195-1208 Protein denotes T-box factors
T22085 1230-1233 Protein denotes TCR
T22086 1269-1274 Protein denotes IFN-γ
T22087 1275-1285 Gene_expression denotes expression
T22088 1249-1258 Positive_regulation denotes essential
T22089 1287-1292 Protein denotes Runx3
T22090 1313-1317 Protein denotes CD8+
T22091 1340-1345 Protein denotes Runx1
T22092 1358-1363 Protein denotes Eomes
T22093 1365-1373 Protein denotes perforin
T22094 1375-1385 Protein denotes granzyme B
T22095 1391-1396 Protein denotes IFN-γ
T22096 1296-1303 Gene_expression denotes present
T22097 1330-1339 Negative_regulation denotes represses
T22098 1397-1407 Gene_expression denotes expression
T22099 1397-1407 Gene_expression denotes expression
T22100 1450-1455 Protein denotes IFN-γ
T22101 1476-1481 Protein denotes Runx3
T22102 1534-1542 Protein denotes perforin
T22103 1456-1466 Gene_expression denotes expression
T22104 1543-1553 Gene_expression denotes expression
T22105 1419-1430 Regulation denotes participate
T22106 1525-1533 Positive_regulation denotes activate
T22107 1623-1632 Protein denotes Gzmb mRNA
T22108 1641-1659 Protein denotes granzyme B protein
T22109 1660-1670 Gene_expression denotes expression
T22110 1660-1670 Gene_expression denotes expression
T22111 1593-1599 Regulation denotes effect
T22112 1593-1599 Regulation denotes effect
R16902 T22048 T22052 causeOf Runx3,controls
R16903 T22048 T22053 causeOf Runx3,controls
R16904 T22048 T22057 causeOf Runx3,controls
R16905 T22048 T22058 causeOf Runx3,controls
R16906 T22048 T22059 causeOf Runx3,controls
R16907 T22049 T22052 themeOf perforin,controls
R16908 T22049 T22054 themeOf perforin,expression
R16909 T22050 T22053 themeOf granzyme B,controls
R16910 T22050 T22055 themeOf granzyme B,expression
R16911 T22051 T22056 themeOf IFN-γ,expression
R16912 T22054 T22057 themeOf expression,controls
R16913 T22055 T22058 themeOf expression,controls
R16914 T22056 T22059 themeOf expression,controls
R16915 T22071 T22074 themeOf Eomes,Overexpression
R16916 T22072 T22075 themeOf VP16,Overexpression
R16917 T22076 T22078 themeOf granzyme B,Expression
R16918 T22077 T22079 themeOf IFN-γ,Expression
R16919 T22080 T22081 themeOf granzyme B,staining
R16920 T22086 T22087 themeOf IFN-γ,expression
R16921 T22087 T22088 themeOf expression,essential
R16922 T22089 T22096 themeOf Runx3,present
R16923 T22089 T22097 causeOf Runx3,represses
R16924 T22091 T22097 themeOf Runx1,represses
R16925 T22092 T22098 themeOf Eomes,expression
R16926 T22095 T22099 themeOf IFN-γ,expression
R16927 T22100 T22103 themeOf IFN-γ,expression
R16928 T22101 T22106 causeOf Runx3,activate
R16929 T22102 T22104 themeOf perforin,expression
R16930 T22103 T22105 themeOf expression,participate
R16931 T22104 T22106 themeOf expression,activate
R16932 T22107 T22109 themeOf Gzmb mRNA,expression
R16933 T22107 T22111 causeOf Gzmb mRNA,effect
R16934 T22107 T22112 causeOf Gzmb mRNA,effect
R16935 T22108 T22110 themeOf granzyme B protein,expression
R16936 T22109 T22111 themeOf expression,effect
R16937 T22110 T22112 themeOf expression,effect

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Negation Speculation
T20893 233-243 Protein denotes Eomes-VP16
T20894 245-252 Protein denotes Eo-VP16
T20895 257-260 Protein denotes Myc
T20896 261-266 Protein denotes Runx3
T20897 268-273 Protein denotes Runx3
T20898 482-496 Positive_regulation denotes Overexpression
T20899 500-510 Protein denotes Eomes-VP16
T20900 539-544 Protein denotes Eomes
T20901 634-638 Protein denotes VP16
T20902 667-677 Gene_expression denotes Expression true
T20903 667-677 Gene_expression denotes Expression true
T20904 681-691 Protein denotes granzyme B
T20905 696-701 Protein denotes IFN-γ
T20929 1397-1407 Gene_expression denotes expression
T20930 1397-1407 Gene_expression denotes expression
T20931 1397-1407 Gene_expression denotes expression
T20932 1409-1414 Protein denotes Eomes
T20933 1419-1430 Regulation denotes participate true
T20934 1450-1455 Protein denotes IFN-γ
T20935 1456-1466 Gene_expression denotes expression
T20936 1476-1481 Protein denotes Runx3
T20937 1486-1491 Protein denotes Eomes
T20938 1501-1506 Protein denotes T-bet
T20939 1525-1533 Positive_regulation denotes activate true
T20940 1525-1533 Positive_regulation denotes activate true
T20941 1525-1533 Positive_regulation denotes activate true true
T20942 1534-1542 Protein denotes perforin
T20943 1543-1553 Gene_expression denotes expression
T20944 1593-1599 Regulation denotes effect
T20945 1593-1599 Regulation denotes effect
T20946 1603-1608 Protein denotes T-bet
T20947 1609-1619 Negative_regulation denotes deficiency
T20948 1623-1627 Protein denotes Gzmb
T20949 1641-1651 Protein denotes granzyme B
T20950 1660-1670 Gene_expression denotes expression
T20951 1660-1670 Gene_expression denotes expression true
T20876 10-15 Protein denotes Runx3
T20877 16-24 Regulation denotes controls
T20878 16-24 Regulation denotes controls
T20879 16-24 Regulation denotes controls
T20880 16-24 Regulation denotes controls
T20881 25-30 Protein denotes Eomes
T20882 32-40 Protein denotes perforin
T20883 42-52 Protein denotes granzyme B
T20884 58-63 Protein denotes IFN-γ
T20885 64-74 Gene_expression denotes expression
T20886 64-74 Gene_expression denotes expression
T20887 64-74 Gene_expression denotes expression
T20888 64-74 Gene_expression denotes expression
T20889 93-98 Protein denotes Runx3
T20890 105-110 Protein denotes Runx3
T20891 114-117 Protein denotes CD8
T20892 197-200 Protein denotes GFP
T20906 924-934 Protein denotes granzyme B
T20907 935-943 Gene_expression denotes staining true
T20908 1042-1045 Protein denotes GFP
T20909 1185-1190 Protein denotes Runx3
T20910 1210-1215 Protein denotes T-bet
T20911 1219-1226 Positive_regulation denotes induced
T20912 1249-1258 Positive_regulation denotes essential
T20913 1269-1274 Protein denotes IFN-γ
T20914 1275-1285 Gene_expression denotes expression
T20915 1287-1292 Protein denotes Runx3
T20916 1296-1303 Gene_expression denotes present
T20917 1313-1316 Protein denotes CD8
T20918 1330-1339 Negative_regulation denotes represses
T20919 1340-1345 Protein denotes Runx1
T20920 1350-1357 Positive_regulation denotes induces
T20921 1350-1357 Positive_regulation denotes induces
T20922 1350-1357 Positive_regulation denotes induces
T20923 1350-1357 Positive_regulation denotes induces
T20924 1358-1363 Protein denotes Eomes
T20925 1365-1373 Protein denotes perforin
T20926 1375-1385 Protein denotes granzyme B
T20927 1391-1396 Protein denotes IFN-γ
T20928 1397-1407 Gene_expression denotes expression
R15999 T20930 T20923 themeOf expression,induces
R15965 T20876 T20880 causeOf Runx3,controls
R15971 T20883 T20885 themeOf granzyme B,expression
R15972 T20884 T20888 themeOf IFN-γ,expression
R15974 T20886 T20879 themeOf expression,controls
R15976 T20888 T20880 themeOf expression,controls
R15977 T20894 T20893 equivalentTo Eo-VP16,Eomes-VP16
R15978 T20899 T20898 themeOf Eomes-VP16,Overexpression
R15979 T20904 T20903 themeOf granzyme B,Expression
R15980 T20905 T20902 themeOf IFN-γ,Expression
R15981 T20906 T20907 themeOf granzyme B,staining
R15982 T20910 T20911 themeOf T-bet,induced
R15983 T20910 T20912 causeOf T-bet,essential
R15984 T20913 T20914 themeOf IFN-γ,expression
R15985 T20914 T20912 themeOf expression,essential
R15986 T20915 T20916 themeOf Runx3,present
R15987 T20915 T20918 causeOf Runx3,represses
R15988 T20915 T20923 causeOf Runx3,induces
R15992 T20919 T20918 themeOf Runx1,represses
R15993 T20924 T20930 themeOf Eomes,expression
R15966 T20876 T20879 causeOf Runx3,controls
R15967 T20876 T20878 causeOf Runx3,controls
R15968 T20876 T20877 causeOf Runx3,controls
R15969 T20881 T20886 themeOf Eomes,expression
R15970 T20882 T20887 themeOf perforin,expression
R15973 T20885 T20877 themeOf expression,controls
R15975 T20887 T20878 themeOf expression,controls
R15989 T20915 T20921 causeOf Runx3,induces
R15990 T20915 T20922 causeOf Runx3,induces
R15991 T20915 T20920 causeOf Runx3,induces
R15994 T20925 T20931 themeOf perforin,expression
R15995 T20926 T20928 themeOf granzyme B,expression
R15996 T20927 T20929 themeOf IFN-γ,expression
R15997 T20928 T20922 themeOf expression,induces
R15998 T20929 T20920 themeOf expression,induces
R16000 T20931 T20921 themeOf expression,induces
R16001 T20932 T20933 causeOf Eomes,participate
R16002 T20934 T20935 themeOf IFN-γ,expression
R16003 T20935 T20933 themeOf expression,participate
R16004 T20936 T20940 causeOf Runx3,activate
R16005 T20937 T20939 causeOf Eomes,activate
R16006 T20938 T20941 causeOf T-bet,activate
R16007 T20942 T20943 themeOf perforin,expression
R16008 T20943 T20940 themeOf expression,activate
R16009 T20943 T20939 themeOf expression,activate
R16010 T20943 T20941 themeOf expression,activate
R16011 T20946 T20947 themeOf T-bet,deficiency
R16012 T20947 T20944 causeOf deficiency,effect
R16013 T20947 T20945 causeOf deficiency,effect
R16014 T20948 T20950 themeOf Gzmb,expression
R16015 T20949 T20951 themeOf granzyme B,expression
R16016 T20950 T20944 themeOf expression,effect
R16017 T20951 T20945 themeOf expression,effect

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T21567 10-15 Q13761 denotes Runx3
T21568 25-30 O95936 denotes Eomes
T21569 32-40 P14222 denotes perforin
T21570 42-52 P10144 denotes granzyme B
T21571 58-63 P01579 denotes IFN-γ
T21572 93-98 Q13761 denotes Runx3
T21573 105-110 Q13761 denotes Runx3
T21574 114-117 P01732 denotes CD8
T21575 114-117 P10966 denotes CD8
T21576 197-200 Q9U6Y4 denotes GFP
T21577 211-214 Q9U6Y4 denotes GFP
T21578 233-238 O95936 denotes Eomes
T21579 245-252 O95936 denotes Eo-VP16
T21580 257-260 P01106 denotes Myc
T21581 261-266 Q13761 denotes Runx3
T21582 268-273 Q13761 denotes Runx3
T21583 369-372 Q9U6Y4 denotes GFP
T21584 500-505 O95936 denotes Eomes
T21585 539-544 O95936 denotes Eomes
T21586 681-691 P10144 denotes granzyme B
T21587 696-701 P01579 denotes IFN-γ
T21588 924-934 P10144 denotes granzyme B
T21589 1042-1045 Q9U6Y4 denotes GFP
T21590 1185-1190 Q13761 denotes Runx3
T21591 1210-1215 Q9UL17 denotes T-bet
T21592 1269-1274 P01579 denotes IFN-γ
T21593 1287-1292 Q13761 denotes Runx3
T21594 1313-1316 P01732 denotes CD8
T21595 1313-1316 P10966 denotes CD8
T21596 1340-1345 Q01196 denotes Runx1
T21597 1358-1363 O95936 denotes Eomes
T21598 1365-1373 P14222 denotes perforin
T21599 1375-1385 P10144 denotes granzyme B
T21600 1391-1396 P01579 denotes IFN-γ
T21601 1409-1414 O95936 denotes Eomes
T21602 1450-1455 P01579 denotes IFN-γ
T21603 1476-1481 Q13761 denotes Runx3
T21604 1486-1491 O95936 denotes Eomes
T21605 1501-1506 Q9UL17 denotes T-bet
T21606 1534-1542 P14222 denotes perforin
T21607 1603-1608 Q9UL17 denotes T-bet
T21608 1623-1627 P10144 denotes Gzmb
T21609 1641-1651 P10144 denotes granzyme B

test2

Id Subject Object Predicate Lexical cue Negation Speculation
T20820 10-15 Protein denotes Runx3
T20821 16-24 Regulation denotes controls
T20822 25-30 Protein denotes Eomes
T20823 32-40 Protein denotes perforin
T20824 42-52 Protein denotes granzyme B
T20825 58-63 Protein denotes IFN-γ
T20826 64-74 Gene_expression denotes expression
T20827 93-98 Protein denotes Runx3
T20828 105-110 Protein denotes Runx3
T20829 114-117 Protein denotes CD8 true
T20830 197-200 Protein denotes GFP true
T20831 233-243 Protein denotes Eomes-VP16 true
T20832 245-252 Protein denotes Eo-VP16
T20833 257-260 Protein denotes Myc
T20834 261-266 Protein denotes Runx3
T20835 268-273 Protein denotes Runx3
T20836 482-496 Positive_regulation denotes Overexpression
T20837 500-510 Protein denotes Eomes-VP16
T20838 539-544 Protein denotes Eomes
T20839 634-638 Protein denotes VP16
T20840 667-677 Gene_expression denotes Expression
T20841 681-691 Protein denotes granzyme B
T20842 696-701 Protein denotes IFN-γ
T20843 924-934 Protein denotes granzyme B
T20844 1042-1045 Protein denotes GFP
T20845 1185-1190 Protein denotes Runx3 true
T20846 1210-1215 Protein denotes T-bet
T20847 1219-1226 Positive_regulation denotes induced true
T20848 1249-1258 Positive_regulation denotes essential
T20849 1269-1274 Protein denotes IFN-γ true
T20850 1275-1285 Gene_expression denotes expression true true
T20851 1287-1292 Protein denotes Runx3
T20852 1313-1316 Protein denotes CD8
T20853 1330-1339 Negative_regulation denotes represses
T20854 1340-1345 Protein denotes Runx1
T20855 1350-1357 Positive_regulation denotes induces true
T20856 1358-1363 Protein denotes Eomes
T20857 1365-1373 Protein denotes perforin
T20858 1375-1385 Protein denotes granzyme B
T20859 1391-1396 Protein denotes IFN-γ
T20860 1397-1407 Gene_expression denotes expression
T20861 1409-1414 Protein denotes Eomes
T20862 1434-1444 Positive_regulation denotes sustaining
T20863 1450-1455 Protein denotes IFN-γ
T20864 1456-1466 Gene_expression denotes expression
T20865 1476-1481 Protein denotes Runx3
T20866 1486-1491 Protein denotes Eomes
T20867 1501-1506 Protein denotes T-bet
T20868 1525-1533 Positive_regulation denotes activate
T20869 1534-1542 Protein denotes perforin
T20870 1543-1553 Gene_expression denotes expression
T20871 1603-1608 Protein denotes T-bet
T20872 1609-1619 Negative_regulation denotes deficiency
T20873 1623-1627 Protein denotes Gzmb
T20874 1641-1651 Protein denotes granzyme B
T20875 1660-1670 Gene_expression denotes expression
R15933 T20820 T20821 causeOf Runx3,controls
R15934 T20822 T20826 themeOf Eomes,expression
R15935 T20823 T20826 themeOf perforin,expression
R15936 T20824 T20826 themeOf granzyme B,expression
R15937 T20825 T20826 themeOf IFN-γ,expression
R15938 T20826 T20821 themeOf expression,controls
R15939 T20832 T20831 equivalentTo Eo-VP16,Eomes-VP16
R15940 T20837 T20836 themeOf Eomes-VP16,Overexpression
R15941 T20841 T20840 themeOf granzyme B,Expression
R15942 T20842 T20840 themeOf IFN-γ,Expression
R15943 T20846 T20848 causeOf T-bet,essential
R15944 T20846 T20847 themeOf T-bet,induced
R15945 T20849 T20850 themeOf IFN-γ,expression
R15946 T20850 T20848 themeOf expression,essential
R15947 T20854 T20855 causeOf Runx1,induces
R15948 T20856 T20860 themeOf Eomes,expression
R15949 T20857 T20860 themeOf perforin,expression
R15950 T20858 T20860 themeOf granzyme B,expression
R15951 T20859 T20860 themeOf IFN-γ,expression
R15952 T20860 T20855 themeOf expression,induces
R15953 T20861 T20862 causeOf Eomes,sustaining
R15954 T20861 T20868 causeOf Eomes,activate
R15955 T20863 T20864 themeOf IFN-γ,expression
R15956 T20864 T20862 themeOf expression,sustaining
R15957 T20865 T20868 causeOf Runx3,activate
R15958 T20866 T20868 causeOf Eomes,activate
R15959 T20867 T20868 causeOf T-bet,activate
R15960 T20869 T20870 themeOf perforin,expression
R15961 T20870 T20868 themeOf expression,activate
R15962 T20871 T20872 themeOf T-bet,deficiency
R15963 T20873 T20875 themeOf Gzmb,expression
R15964 T20874 T20875 themeOf granzyme B,expression