PMC:2626671 / 10885-13900 JSON TXT

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2_test

Id	Subject	Object	Predicate	Lexical cue
19139168-11786644-59674047	270-272	11786644	denotes	17
19139168-14673093-59674048	274-276	14673093	denotes	21
19139168-16273099-59674049	2492-2493	16273099	denotes	8

pmc-enju-pas

Id	Subject	Object	Predicate	Lexical cue
T6493	0-8	NN	denotes	Perforin
T6494	9-12	CC	denotes	and
T6495	13-21	NN	denotes	granzyme
T6496	22-23	NN	denotes	B
T6497	24-34	NN	denotes	expression
T6498	35-38	VB	denotes	are
T6499	39-42	RB	denotes	not
T6500	43-54	RB	denotes	appreciably
T6501	55-64	VB	denotes	regulated
T6502	65-67	IN	denotes	by
T6503	68-73	NN	denotes	T-bet
T6504	74-76	TO	denotes	To
T6505	77-81	VB	denotes	test
T6506	82-85	DT	denotes	the
T6507	86-91	NN	denotes	model
T6508	92-100	VB	denotes	outlined
T6509	101-103	IN	denotes	in
T6510	104-107	DT	denotes	the
T6511	108-116	JJ	denotes	previous
T6512	117-126	NN	denotes	paragraph
T6513	127-135	RB	denotes	directly
T6514	135-136	-COMMA-	denotes	,
T6515	137-139	PRP	denotes	we
T6516	140-148	VB	denotes	compared
T6517	149-152	DT	denotes	the
T6518	153-163	NN	denotes	expression
T6519	164-166	IN	denotes	of
T6520	167-172	NN	denotes	IFN-γ
T6521	172-173	-COMMA-	denotes	,
T6522	174-182	NN	denotes	perforin
T6523	182-183	-COMMA-	denotes	,
T6524	184-187	CC	denotes	and
T6525	188-196	NN	denotes	granzyme
T6526	197-198	NN	denotes	B
T6527	199-201	IN	denotes	in
T6528	202-206	JJ	denotes	CD8+
T6529	207-208	NN	denotes	T
T6530	209-214	NN	denotes	cells
T6531	215-219	IN	denotes	from
T6532	220-222	NN	denotes	WT
T6533	223-226	CC	denotes	and
T6534	227-232	NN	denotes	Tbx21
T6535	233-234	-LRB-	denotes	(
T6536	234-239	NN	denotes	T-bet
T6537	239-240	-RRB-	denotes	)
T6538	240-250	JJ	denotes	-deficient
T6539	251-255	NN	denotes	mice
T6540	257-259	IN	denotes	As
T6541	260-268	VB	denotes	expected
T6542	269-270	-LRB-	denotes	(
T6543	270-272	CD	denotes	17
T6544	272-273	-COMMA-	denotes	,
T6545	274-276	CD	denotes	21
T6546	276-277	-RRB-	denotes	)
T6547	277-278	-COMMA-	denotes	,
T6548	279-284	JJ	denotes	naive
T6549	285-293	NN	denotes	Tbx21−/−
T6550	294-298	JJ	denotes	CD8+
T6551	299-300	NN	denotes	T
T6552	301-306	NN	denotes	cells
T6553	307-315	VB	denotes	produced
T6554	316-321	NN	denotes	IFN-γ
T6555	322-328	RB	denotes	poorly
T6556	329-333	IN	denotes	upon
T6557	334-344	NN	denotes	activation
T6558	345-346	-LRB-	denotes	(
T6559	346-350	NN	denotes	Fig.
T6560	351-352	CD	denotes	2
T6561	353-354	NN	denotes	A
T6562	354-355	-RRB-	denotes	)
T6563	357-364	RB	denotes	Notably
T6564	364-365	-COMMA-	denotes	,
T6565	366-370	DT	denotes	this
T6566	371-382	JJ	denotes	deleterious
T6567	383-389	NN	denotes	effect
T6568	390-392	IN	denotes	of
T6569	393-398	NN	denotes	T-bet
T6570	399-409	NN	denotes	deficiency
T6571	410-413	VB	denotes	was
T6572	414-418	RB	denotes	only
T6573	419-427	VB	denotes	observed
T6574	428-430	IN	denotes	in
T6575	431-446	VB	denotes	differentiating
T6576	447-451	JJ	denotes	CD8+
T6577	452-453	NN	denotes	T
T6578	454-459	NN	denotes	cells
T6579	460-465	IN	denotes	until
T6580	466-469	NN	denotes	day
T6581	470-471	CD	denotes	4
T6582	472-474	IN	denotes	of
T6583	475-482	NN	denotes	culture
T6584	483-486	CC	denotes	but
T6585	487-490	VB	denotes	was
T6586	491-497	RB	denotes	almost
T6587	498-508	RB	denotes	completely
T6588	509-518	VB	denotes	mitigated
T6589	519-521	IN	denotes	by
T6590	522-525	NN	denotes	day
T6591	526-527	CD	denotes	6
T6592	528-529	-LRB-	denotes	(
T6593	529-533	NN	denotes	Fig.
T6594	534-535	CD	denotes	2
T6595	536-537	NN	denotes	A
T6596	537-538	-RRB-	denotes	)
T6597	540-544	DT	denotes	This
T6598	545-549	RB	denotes	most
T6599	550-556	JJ	denotes	likely
T6600	557-566	VB	denotes	reflected
T6601	567-579	NN	denotes	compensation
T6602	580-582	IN	denotes	by
T6603	583-588	NN	denotes	Eomes
T6604	588-589	-COMMA-	denotes	,
T6605	590-595	WDT	denotes	which
T6606	596-599	VB	denotes	was
T6607	600-608	RB	denotes	strongly
T6608	609-616	VB	denotes	induced
T6609	617-624	IN	denotes	between
T6610	625-629	NN	denotes	days
T6611	630-631	CD	denotes	4
T6612	632-635	CC	denotes	and
T6613	636-637	CD	denotes	6
T6614	638-639	-LRB-	denotes	(
T6615	639-643	NN	denotes	Fig.
T6616	644-645	CD	denotes	1
T6617	645-646	-RRB-	denotes	)
T6618	648-650	IN	denotes	In
T6619	651-659	NN	denotes	contrast
T6620	659-660	-COMMA-	denotes	,
T6621	661-676	JJ	denotes	T-bet–deficient
T6622	677-678	NN	denotes	T
T6623	679-684	NN	denotes	cells
T6624	685-693	VB	denotes	cultured
T6625	694-697	IN	denotes	for
T6626	698-699	CD	denotes	6
T6627	700-701	NN	denotes	d
T6628	702-708	VB	denotes	showed
T6629	709-711	DT	denotes	no
T6630	712-718	NN	denotes	defect
T6631	719-721	IN	denotes	in
T6632	722-730	NN	denotes	perforin
T6633	731-735	NN	denotes	mRNA
T6634	736-746	NN	denotes	expression
T6635	747-748	-LRB-	denotes	(
T6636	748-752	NN	denotes	Fig.
T6637	753-754	CD	denotes	2
T6638	755-756	NN	denotes	B
T6639	756-757	-COMMA-	denotes	,
T6640	758-765	VB	denotes	compare
T6641	766-771	NN	denotes	lanes
T6642	772-773	CD	denotes	1
T6643	774-777	CC	denotes	and
T6644	778-779	CD	denotes	4
T6645	779-780	-RRB-	denotes	)
T6646	782-784	PRP	denotes	We
T6647	785-797	RB	denotes	consistently
T6648	798-806	VB	denotes	observed
T6649	807-808	DT	denotes	a
T6650	809-815	JJ	denotes	modest
T6651	816-825	NN	denotes	reduction
T6652	826-828	IN	denotes	in
T6653	829-833	NN	denotes	GzmB
T6654	834-838	NN	denotes	mRNA
T6655	839-841	IN	denotes	in
T6656	842-857	JJ	denotes	T-bet–deficient
T6657	858-859	NN	denotes	T
T6658	860-865	NN	denotes	cells
T6659	866-867	-LRB-	denotes	(
T6660	867-871	NN	denotes	Fig.
T6661	872-873	CD	denotes	2
T6662	874-875	NN	denotes	B
T6663	875-876	-COMMA-	denotes	,
T6664	877-884	VB	denotes	compare
T6665	885-890	NN	denotes	lanes
T6666	891-892	CD	denotes	1
T6667	893-896	CC	denotes	and
T6668	897-898	CD	denotes	4
T6669	898-899	-RRB-	denotes	)
T6670	899-900	-COMMA-	denotes	,
T6671	901-906	WDT	denotes	which
T6672	907-910	VB	denotes	did
T6673	911-914	RB	denotes	not
T6674	915-924	VB	denotes	translate
T6675	925-929	IN	denotes	into
T6676	930-931	DT	denotes	a
T6677	932-940	NN	denotes	decrease
T6678	941-943	IN	denotes	in
T6679	944-954	NN	denotes	expression
T6680	955-957	IN	denotes	of
T6681	958-966	NN	denotes	granzyme
T6682	967-968	NN	denotes	B
T6683	969-976	NN	denotes	protein
T6684	977-978	-LRB-	denotes	(
T6685	978-982	NN	denotes	Fig.
T6686	983-984	CD	denotes	2
T6687	985-986	NN	denotes	C
T6688	986-987	-RRB-	denotes	)
T6689	2245-2247	TO	denotes	To
T6690	2248-2255	VB	denotes	examine
T6691	2256-2259	DT	denotes	the
T6692	2260-2264	NN	denotes	role
T6693	2265-2267	IN	denotes	of
T6694	2268-2273	NN	denotes	Eomes
T6695	2273-2274	-COMMA-	denotes	,
T6696	2275-2277	PRP	denotes	we
T6697	2278-2288	VB	denotes	transduced
T6698	2289-2294	JJ	denotes	naive
T6699	2295-2299	JJ	denotes	CD8+
T6700	2300-2301	NN	denotes	T
T6701	2302-2307	NN	denotes	cells
T6702	2308-2312	IN	denotes	from
T6703	2313-2315	NN	denotes	WT
T6704	2316-2319	CC	denotes	and
T6705	2320-2328	NN	denotes	Tbx21−/−
T6706	2329-2333	NN	denotes	mice
T6707	2334-2338	IN	denotes	with
T6708	2339-2351	NN	denotes	retroviruses
T6709	2352-2362	VB	denotes	containing
T6710	2363-2371	JJ	denotes	internal
T6711	2372-2380	NN	denotes	ribosome
T6712	2381-2386	NN	denotes	entry
T6713	2387-2391	NN	denotes	site
T6714	2392-2393	-LRB-	denotes	(
T6715	2393-2397	NN	denotes	IRES
T6716	2397-2398	-RRB-	denotes	)
T6717	2398-2402	NN	denotes	–GFP
T6718	2403-2407	WDT	denotes	that
T6719	2408-2412	VB	denotes	were
T6720	2413-2419	CC	denotes	either
T6721	2420-2425	JJ	denotes	empty
T6722	2426-2428	CC	denotes	or
T6723	2429-2436	VB	denotes	encoded
T6724	2437-2438	DT	denotes	a
T6725	2439-2447	RB	denotes	strongly
T6726	2448-2463	VB	denotes	transactivating
T6727	2464-2471	NN	denotes	version
T6728	2472-2474	IN	denotes	of
T6729	2475-2480	NN	denotes	Eomes
T6730	2481-2482	-LRB-	denotes	(
T6731	2482-2489	NN	denotes	Eo-VP16
T6732	2489-2490	-RRB-	denotes	)
T6733	2491-2492	-LRB-	denotes	(
T6734	2492-2493	CD	denotes	8
T6735	2493-2494	-RRB-	denotes	)
T6736	2494-2495	-COMMA-	denotes	,
T6737	2496-2499	CC	denotes	and
T6738	2500-2508	VB	denotes	expanded
T6739	2509-2513	PRP	denotes	them
T6740	2514-2517	IN	denotes	for
T6741	2518-2519	CD	denotes	6
T6742	2520-2521	NN	denotes	d
T6743	2522-2527	IN	denotes	under
T6744	2528-2531	PRP-DOLLAR-	denotes	our
T6745	2532-2539	NN	denotes	culture
T6746	2540-2550	NN	denotes	conditions
T6747	2552-2559	NN	denotes	Eo-VP16
T6748	2559-2560	-COMMA-	denotes	,
T6749	2561-2564	CC	denotes	but
T6750	2565-2568	RB	denotes	not
T6751	2569-2572	DT	denotes	the
T6752	2573-2578	JJ	denotes	empty
T6753	2579-2582	NN	denotes	GFP
T6754	2583-2593	NN	denotes	retrovirus
T6755	2593-2594	-COMMA-	denotes	,
T6756	2595-2604	VB	denotes	increased
T6757	2605-2613	NN	denotes	perforin
T6758	2614-2624	NN	denotes	expression
T6759	2625-2627	IN	denotes	in
T6760	2628-2632	CC	denotes	both
T6761	2633-2635	NN	denotes	WT
T6762	2636-2639	CC	denotes	and
T6763	2640-2655	JJ	denotes	T-bet–deficient
T6764	2656-2660	JJ	denotes	CD8+
T6765	2661-2662	NN	denotes	T
T6766	2663-2668	NN	denotes	cells
T6767	2669-2670	-LRB-	denotes	(
T6768	2670-2674	NN	denotes	Fig.
T6769	2675-2676	CD	denotes	2
T6770	2677-2678	NN	denotes	B
T6771	2678-2679	-COMMA-	denotes	,
T6772	2680-2685	NN	denotes	lanes
T6773	2686-2687	CD	denotes	2
T6774	2687-2688	-COMMA-	denotes	,
T6775	2689-2690	CD	denotes	3
T6776	2690-2691	-COMMA-	denotes	,
T6777	2692-2693	CD	denotes	5
T6778	2693-2694	-COMMA-	denotes	,
T6779	2695-2698	CC	denotes	and
T6780	2699-2700	CD	denotes	6
T6781	2700-2701	-RRB-	denotes	)
T6782	2703-2705	IN	denotes	As
T6783	2706-2714	VB	denotes	expected
T6784	2714-2715	-COMMA-	denotes	,
T6785	2716-2723	NN	denotes	Eo-VP16
T6786	2724-2728	RB	denotes	also
T6787	2729-2736	VB	denotes	rescued
T6788	2737-2740	DT	denotes	the
T6789	2741-2746	JJ	denotes	early
T6790	2747-2753	NN	denotes	defect
T6791	2754-2756	IN	denotes	in
T6792	2757-2762	NN	denotes	IFN-γ
T6793	2763-2773	NN	denotes	production
T6794	2774-2782	VB	denotes	observed
T6795	2783-2785	IN	denotes	in
T6796	2786-2801	JJ	denotes	T-bet–deficient
T6797	2802-2806	JJ	denotes	CD8+
T6798	2807-2808	NN	denotes	T
T6799	2809-2814	NN	denotes	cells
T6800	2815-2816	-LRB-	denotes	(
T6801	2816-2820	NN	denotes	Fig.
T6802	2821-2822	CD	denotes	2
T6803	2823-2824	NN	denotes	D
T6804	2824-2825	-RRB-	denotes	)
T6805	2827-2834	RB	denotes	However
T6806	2834-2835	-COMMA-	denotes	,
T6807	2836-2843	NN	denotes	Eo-VP16
T6808	2844-2847	VB	denotes	did
T6809	2848-2851	RB	denotes	not
T6810	2852-2858	VB	denotes	induce
T6811	2859-2863	NN	denotes	GzmB
T6812	2864-2868	NN	denotes	mRNA
T6813	2869-2879	NN	denotes	expression
T6814	2880-2882	IN	denotes	in
T6815	2883-2889	CC	denotes	either
T6816	2890-2892	NN	denotes	WT
T6817	2893-2895	CC	denotes	or
T6818	2896-2911	JJ	denotes	T-bet–deficient
T6819	2912-2917	NN	denotes	cells
T6820	2917-2918	-COLON-	denotes	;
T6821	2919-2923	RB	denotes	thus
T6822	2923-2924	-COMMA-	denotes	,
T6823	2925-2928	DT	denotes	the
T6824	2929-2936	JJ	denotes	partial
T6825	2937-2942	NN	denotes	T-bet
T6826	2943-2953	NN	denotes	dependence
T6827	2954-2956	IN	denotes	of
T6828	2957-2961	NN	denotes	GzmB
T6829	2962-2966	NN	denotes	mRNA
T6830	2967-2977	NN	denotes	expression
T6831	2978-2981	MD	denotes	can
T6832	2981-2984	RB	denotes	not
T6833	2985-2987	VB	denotes	be
T6834	2988-2999	VB	denotes	compensated
T6835	3000-3003	IN	denotes	for
T6836	3004-3006	IN	denotes	by
T6837	3007-3014	NN	denotes	Eo-VP16
T19474	999-1009	NN	denotes	Regulation
T19475	1010-1012	IN	denotes	of
T19476	1013-1021	NN	denotes	perforin
T19477	1021-1022	-COMMA-	denotes	,
T19478	1023-1031	NN	denotes	granzyme
T19479	1032-1033	NN	denotes	B
T19480	1033-1034	-COMMA-	denotes	,
T19481	1035-1038	CC	denotes	and
T19482	1039-1044	NN	denotes	IFN-γ
T19483	1045-1055	NN	denotes	expression
T19484	1056-1058	IN	denotes	by
T19485	1059-1064	NN	denotes	T-bet
T19486	1065-1068	CC	denotes	and
T19487	1069-1074	NN	denotes	Eomes
T19488	1075-1077	IN	denotes	in
T19489	1078-1093	VB	denotes	differentiating
T19490	1094-1099	NN	denotes	CTLs.
T19491	1100-1101	-LRB-	denotes	(
T19492	1101-1102	NN	denotes	A
T19493	1102-1103	-RRB-	denotes	)
T19494	1104-1109	NN	denotes	IFN-γ
T19495	1110-1120	NN	denotes	expression
T19496	1121-1123	IN	denotes	by
T19497	1124-1126	NN	denotes	WT
T19498	1127-1128	-LRB-	denotes	(
T19499	1128-1136	NN	denotes	Tbx21+/+
T19500	1136-1137	-RRB-	denotes	)
T19501	1138-1141	CC	denotes	and
T19502	1142-1157	JJ	denotes	T-bet–deficient
T19503	1158-1159	-LRB-	denotes	(
T19504	1159-1167	NN	denotes	Tbx21−/−
T19505	1167-1168	-RRB-	denotes	)
T19506	1169-1170	NN	denotes	T
T19507	1171-1176	NN	denotes	cells
T19508	1178-1183	JJ	denotes	Naive
T19509	1184-1188	JJ	denotes	CD8+
T19510	1189-1190	NN	denotes	T
T19511	1191-1196	NN	denotes	cells
T19512	1196-1197	-COMMA-	denotes	,
T19513	1198-1200	CC	denotes	or
T19514	1201-1206	NN	denotes	cells
T19515	1207-1216	VB	denotes	activated
T19516	1217-1220	CC	denotes	and
T19517	1221-1229	VB	denotes	cultured
T19518	1230-1233	IN	denotes	for
T19519	1234-1235	CD	denotes	4
T19520	1236-1238	CC	denotes	or
T19521	1239-1240	CD	denotes	6
T19522	1241-1242	NN	denotes	d
T19523	1242-1243	-COMMA-	denotes	,
T19524	1244-1248	VB	denotes	were
T19525	1249-1261	VB	denotes	restimulated
T19526	1262-1266	IN	denotes	with
T19527	1267-1270	NN	denotes	PMA
T19528	1271-1274	CC	denotes	and
T19529	1275-1284	NN	denotes	ionomycin
T19530	1285-1288	IN	denotes	for
T19531	1289-1290	CD	denotes	6
T19532	1291-1292	NN	denotes	h
T19533	1292-1293	-COMMA-	denotes	,
T19534	1294-1297	CC	denotes	and
T19535	1298-1303	NN	denotes	IFN-γ
T19536	1304-1314	NN	denotes	expression
T19537	1315-1318	VB	denotes	was
T19538	1319-1327	VB	denotes	assessed
T19539	1328-1330	IN	denotes	by
T19540	1331-1344	JJ	denotes	intracellular
T19541	1345-1353	NN	denotes	staining
T19542	1355-1362	NN	denotes	Numbers
T19543	1363-1367	VB	denotes	show
T19544	1368-1371	DT	denotes	the
T19545	1372-1382	NN	denotes	percentage
T19546	1383-1385	IN	denotes	of
T19547	1386-1392	JJ	denotes	IFN-γ+
T19548	1393-1399	NN	denotes	cells.
T19549	1400-1401	-LRB-	denotes	(
T19550	1401-1402	NN	denotes	B
T19551	1402-1403	-RRB-	denotes	)
T19552	1404-1412	JJ	denotes	Northern
T19553	1413-1417	NN	denotes	blot
T19554	1418-1426	NN	denotes	analysis
T19555	1427-1429	IN	denotes	of
T19556	1430-1434	NN	denotes	Prf1
T19557	1435-1438	CC	denotes	and
T19558	1439-1443	NN	denotes	GzmB
T19559	1444-1448	NN	denotes	mRNA
T19560	1449-1459	NN	denotes	expression
T19561	1460-1462	IN	denotes	in
T19562	1463-1465	NN	denotes	WT
T19563	1466-1468	CC	denotes	or
T19564	1469-1484	JJ	denotes	T-bet–deficient
T19565	1485-1489	JJ	denotes	CD8+
T19566	1490-1491	NN	denotes	T
T19567	1492-1497	NN	denotes	cells
T19568	1498-1507	VB	denotes	activated
T19569	1508-1511	CC	denotes	and
T19570	1512-1518	CC	denotes	either
T19571	1519-1523	JJ	denotes	left
T19572	1524-1534	JJ	denotes	uninfected
T19573	1535-1536	-LRB-	denotes	(
T19574	1536-1541	JJ	denotes	uninf
T19575	1541-1542	-RRB-	denotes	)
T19576	1543-1545	CC	denotes	or
T19577	1546-1556	VB	denotes	transduced
T19578	1557-1561	IN	denotes	with
T19579	1562-1574	NN	denotes	retroviruses
T19580	1575-1585	VB	denotes	expressing
T19581	1586-1596	NN	denotes	Eomes-VP16
T19582	1597-1598	-LRB-	denotes	(
T19583	1598-1605	NN	denotes	Eo-VP16
T19584	1605-1606	-RRB-	denotes	)
T19585	1607-1609	CC	denotes	or
T19586	1610-1612	DT	denotes	an
T19587	1613-1618	JJ	denotes	empty
T19588	1619-1627	NN	denotes	IRES-GFP
T19589	1628-1636	NN	denotes	cassette
T19590	1637-1638	-LRB-	denotes	(
T19591	1638-1641	NN	denotes	GFP
T19592	1641-1642	-RRB-	denotes	)
T19593	1644-1649	JJ	denotes	Total
T19594	1650-1658	JJ	denotes	cellular
T19595	1659-1662	NN	denotes	RNA
T19596	1663-1666	VB	denotes	was
T19597	1667-1675	VB	denotes	analyzed
T19598	1676-1678	IN	denotes	on
T19599	1679-1682	NN	denotes	day
T19600	1683-1684	CD	denotes	6
T19601	1685-1687	IN	denotes	of
T19602	1688-1695	NN	denotes	culture
T19603	1697-1700	DT	denotes	The
T19604	1701-1710	NN	denotes	frequency
T19605	1711-1713	IN	denotes	of
T19606	1714-1724	VB	denotes	transduced
T19607	1725-1730	NN	denotes	cells
T19608	1731-1733	IN	denotes	in
T19609	1734-1737	DT	denotes	the
T19610	1738-1746	NN	denotes	cultures
T19611	1747-1750	VB	denotes	was
T19612	1751-1761	JJ	denotes	equivalent
T19613	1762-1765	IN	denotes	for
T19614	1766-1770	DT	denotes	both
T19615	1771-1781	NN	denotes	constructs
T19616	1782-1783	-LRB-	denotes	(
T19617	1783-1789	CD	denotes	∼65–70
T19618	1789-1790	NN	denotes	%
T19619	1791-1795	NN	denotes	GFP+
T19620	1796-1801	NN	denotes	cells
T19621	1801-1802	-COLON-	denotes	;
T19622	1803-1806	RB	denotes	not
T19623	1807-1815	VB	denotes	depicted
T19624	1815-1816	-RRB-	denotes	)
T19625	1816-1817	-LRB-	denotes	.
T19626	1818-1819	NN	denotes	(
T19627	1819-1820	-RRB-	denotes	C
T19628	1820-1828	NN	denotes	) Granzy
T19629	1828-1829	NN	denotes	m
T19630	1829-1832	CC	denotes	e B
T19631	1833-1838	NN	denotes	and I
T19632	1838-1848	NN	denotes	FN-γ expre
T19633	1848-1850	IN	denotes	ss
T19634	1850-1858	NN	denotes	ion by T
T19635	1858-1861	CC	denotes	bx2
T19636	1861-1869	NN	denotes	1+/+ and
T19637	1870-1871	NN	denotes	T
T19638	1871-1876	NN	denotes	bx21−
T19639	1876-1884	VB	denotes	/− T cel
T19640	1884-1886	IN	denotes	ls
T19641	1887-1899	VB	denotes	analyzed in
T19642	1899-1904	NN	denotes	resti
T19643	1904-1908	WDT	denotes	mula
T19644	1908-1911	VB	denotes	ted
T19645	1912-1916	VB	denotes	cell
T19646	1916-1924	VB	denotes	s that h
T19647	1924-1927	IN	denotes	ad
T19648	1927-1928	CD	denotes	b
T19649	1928-1930	NN	denotes	ee
T19650	1930-1931	-LRB-	denotes	n
T19651	1932-1933	NN	denotes	c
T19652	1933-1934	-RRB-	denotes	u
T19653	1934-1939	NN	denotes	lture
T19654	1939-1949	NN	denotes	d for 5 d.
T19655	1950-1952	IN	denotes	(D
T19656	1952-1957	NN	denotes	) IFN
T19657	1957-1967	VB	denotes	-γ product
T19658	1967-1971	IN	denotes	ion
T19659	1971-1978	NN	denotes	by cell
T19660	1978-1980	CC	denotes	s
T19661	1980-1987	NN	denotes	transdu
T19662	1987-1988	-LRB-	denotes	c
T19663	1988-1991	NN	denotes	ed
T19664	1991-1992	-RRB-	denotes	w
T19665	1992-2004	NN	denotes	ith Eo-VP16
T19666	2004-2005	-LRB-	denotes	o
T19667	2005-2007	NN	denotes	r
T19668	2007-2008	-RRB-	denotes	c
T19669	2008-2016	VB	denotes	ontrol (
T19670	2016-2018	IN	denotes	GF
T19671	2018-2021	NN	denotes	P)
T19672	2021-2022	CD	denotes	r
T19673	2022-2027	IN	denotes	etrov
T19674	2027-2028	CD	denotes	i
T19675	2028-2029	NN	denotes	r
T19676	2029-2031	IN	denotes	us
T19677	2031-2044	NN	denotes	es (RV) measu
T19678	2044-2048	IN	denotes	red
T19679	2048-2051	NN	denotes	on
T19680	2051-2054	CC	denotes	day
T19681	2055-2064	NN	denotes	4 after 6
T19682	2108-2115	NN	denotes	Numbers
T19683	2116-2120	VB	denotes	show
T19684	2121-2124	DT	denotes	the
T19685	2125-2135	NN	denotes	percentage
T19686	2136-2138	IN	denotes	of
T19687	2139-2143	JJ	denotes	GFP+
T19688	2144-2150	JJ	denotes	IFN-γ+
T19689	2151-2156	NN	denotes	cells
T19690	2158-2165	NN	denotes	Results
T19691	2166-2169	VB	denotes	are
T19692	2170-2184	JJ	denotes	representative
T19693	2185-2187	IN	denotes	of
T19694	2188-2193	CD	denotes	three
T19695	2194-2195	-LRB-	denotes	(
T19696	2195-2196	NN	denotes	A
T19697	2197-2200	CC	denotes	and
T19698	2201-2202	NN	denotes	C
T19699	2202-2203	-RRB-	denotes	)
T19700	2204-2206	CC	denotes	or
T19701	2207-2210	CD	denotes	two
T19702	2211-2212	-LRB-	denotes	(
T19703	2212-2213	NN	denotes	B
T19704	2214-2217	CC	denotes	and
T19705	2218-2219	NN	denotes	D
T19706	2219-2220	-RRB-	denotes	)
T19707	2221-2232	JJ	denotes	independent
T19708	2233-2244	NN	denotes	experiments
R5177	T6493	T6494	arg1Of	Perforin,and
R5178	T6494	T6498	arg1Of	and,are
R5179	T6494	T6501	arg2Of	and,regulated
R5180	T6497	T6494	arg2Of	expression,and
R5181	T6497	T6495	arg1Of	expression,granzyme
R5182	T6497	T6496	arg1Of	expression,B
R5183	T6501	T6498	arg2Of	regulated,are
R5184	T6501	T6499	arg1Of	regulated,not
R5185	T6501	T6500	arg1Of	regulated,appreciably
R5186	T6503	T6501	arg1Of	T-bet,regulated
R5187	T6503	T6502	arg2Of	T-bet,by
R5188	T6505	T6504	arg1Of	test,To
R5189	T6507	T6505	arg2Of	model,test
R5190	T6507	T6506	arg1Of	model,the
R5191	T6507	T6508	arg2Of	model,outlined
R5192	T6508	T6509	arg1Of	outlined,in
R5193	T6508	T6513	arg1Of	outlined,directly
R5194	T6512	T6509	arg2Of	paragraph,in
R5195	T6512	T6510	arg1Of	paragraph,the
R5196	T6512	T6511	arg1Of	paragraph,previous
R5197	T6515	T6505	arg1Of	we,test
R5198	T6515	T6516	arg1Of	we,compared
R5199	T6516	T6504	modOf	compared,To
R5200	T6516	T6514	arg1Of	compared,","
R5201	T6518	T6516	arg2Of	expression,compared
R5202	T6518	T6517	arg1Of	expression,the
R5203	T6518	T6519	arg1Of	expression,of
R5204	T6518	T6527	arg1Of	expression,in
R5205	T6520	T6521	arg1Of	IFN-γ,","
R5206	T6521	T6524	arg1Of	",",and
R5207	T6522	T6521	arg2Of	perforin,","
R5208	T6524	T6519	arg2Of	and,of
R5209	T6524	T6523	arg1Of	and,","
R5210	T6526	T6524	arg2Of	B,and
R5211	T6526	T6525	arg1Of	B,granzyme
R5212	T6530	T6527	arg2Of	cells,in
R5213	T6530	T6528	arg1Of	cells,CD8+
R5214	T6530	T6529	arg1Of	cells,T
R5215	T6530	T6531	arg1Of	cells,from
R5216	T6532	T6533	arg1Of	WT,and
R5217	T6534	T6533	arg2Of	Tbx21,and
R5218	T6536	T6535	arg2Of	T-bet,(
R5219	T6537	T6535	arg3Of	),(
R5220	T6539	T6531	arg2Of	mice,from
R5221	T6539	T6532	arg1Of	mice,WT
R5222	T6539	T6534	arg1Of	mice,Tbx21
R5223	T6539	T6535	arg1Of	mice,(
R5224	T6539	T6538	arg1Of	mice,-deficient
R5225	T6541	T6540	arg2Of	expected,As
R5226	T6541	T6542	arg1Of	expected,(
R5227	T6543	T6544	arg1Of	17,","
R5228	T6544	T6542	arg2Of	",",(
R5229	T6545	T6544	arg2Of	21,","
R5230	T6546	T6542	arg3Of	),(
R5231	T6552	T6548	arg1Of	cells,naive
R5232	T6552	T6549	arg1Of	cells,Tbx21−/−
R5233	T6552	T6550	arg1Of	cells,CD8+
R5234	T6552	T6551	arg1Of	cells,T
R5235	T6552	T6553	arg1Of	cells,produced
R5236	T6553	T6540	arg1Of	produced,As
R5237	T6553	T6547	arg1Of	produced,","
R5238	T6553	T6555	arg1Of	produced,poorly
R5239	T6553	T6556	arg1Of	produced,upon
R5240	T6554	T6553	arg2Of	IFN-γ,produced
R5241	T6557	T6556	arg2Of	activation,upon
R5242	T6557	T6558	arg1Of	activation,(
R5243	T6561	T6558	arg2Of	A,(
R5244	T6561	T6559	arg1Of	A,Fig.
R5245	T6561	T6560	arg1Of	A,2
R5246	T6562	T6558	arg3Of	),(
R5247	T6567	T6565	arg1Of	effect,this
R5248	T6567	T6566	arg1Of	effect,deleterious
R5249	T6567	T6568	arg1Of	effect,of
R5250	T6567	T6571	arg1Of	effect,was
R5251	T6567	T6573	arg2Of	effect,observed
R5252	T6567	T6585	arg1Of	effect,was
R5253	T6567	T6588	arg2Of	effect,mitigated
R5254	T6570	T6568	arg2Of	deficiency,of
R5255	T6570	T6569	arg1Of	deficiency,T-bet
R5256	T6573	T6571	arg2Of	observed,was
R5257	T6573	T6572	arg1Of	observed,only
R5258	T6573	T6574	arg1Of	observed,in
R5259	T6573	T6579	arg1Of	observed,until
R5260	T6573	T6584	arg1Of	observed,but
R5261	T6578	T6574	arg2Of	cells,in
R5262	T6578	T6575	arg1Of	cells,differentiating
R5263	T6578	T6576	arg1Of	cells,CD8+
R5264	T6578	T6577	arg1Of	cells,T
R5265	T6580	T6579	arg2Of	day,until
R5266	T6580	T6581	arg1Of	day,4
R5267	T6580	T6582	arg1Of	day,of
R5268	T6583	T6582	arg2Of	culture,of
R5269	T6584	T6563	arg1Of	but,Notably
R5270	T6584	T6564	arg1Of	but,","
R5271	T6587	T6586	arg1Of	completely,almost
R5272	T6588	T6584	arg2Of	mitigated,but
R5273	T6588	T6585	arg2Of	mitigated,was
R5274	T6588	T6587	arg1Of	mitigated,completely
R5275	T6588	T6589	arg1Of	mitigated,by
R5276	T6590	T6589	arg2Of	day,by
R5277	T6590	T6591	arg1Of	day,6
R5278	T6590	T6592	arg1Of	day,(
R5279	T6595	T6592	arg2Of	A,(
R5280	T6595	T6593	arg1Of	A,Fig.
R5281	T6595	T6594	arg1Of	A,2
R5282	T6596	T6592	arg3Of	),(
R5283	T6599	T6598	arg1Of	likely,most
R5284	T6601	T6597	arg1Of	compensation,This
R5285	T6601	T6599	arg1Of	compensation,likely
R5286	T6601	T6600	arg2Of	compensation,reflected
R5287	T6601	T6602	arg1Of	compensation,by
R5288	T6601	T6604	arg1Of	compensation,","
R5289	T6601	T6605	arg1Of	compensation,which
R5290	T6601	T6606	arg1Of	compensation,was
R5291	T6601	T6608	arg2Of	compensation,induced
R5292	T6603	T6602	arg2Of	Eomes,by
R5293	T6608	T6606	arg2Of	induced,was
R5294	T6608	T6607	arg1Of	induced,strongly
R5295	T6608	T6609	arg1Of	induced,between
R5296	T6611	T6612	arg1Of	4,and
R5297	T6612	T6609	arg2Of	and,between
R5298	T6612	T6610	arg1Of	and,days
R5299	T6612	T6614	arg1Of	and,(
R5300	T6613	T6612	arg2Of	6,and
R5301	T6615	T6614	arg2Of	Fig.,(
R5302	T6615	T6616	arg1Of	Fig.,1
R5303	T6617	T6614	arg3Of	),(
R5304	T6619	T6618	arg2Of	contrast,In
R5305	T6623	T6621	arg1Of	cells,T-bet–deficient
R5306	T6623	T6622	arg1Of	cells,T
R5307	T6623	T6624	arg2Of	cells,cultured
R5308	T6623	T6628	arg1Of	cells,showed
R5309	T6624	T6625	arg1Of	cultured,for
R5310	T6627	T6625	arg2Of	d,for
R5311	T6627	T6626	arg1Of	d,6
R5312	T6628	T6618	arg1Of	showed,In
R5313	T6628	T6620	arg1Of	showed,","
R5314	T6628	T6631	arg1Of	showed,in
R5315	T6630	T6628	arg2Of	defect,showed
R5316	T6630	T6629	arg1Of	defect,no
R5317	T6634	T6631	arg2Of	expression,in
R5318	T6634	T6632	arg1Of	expression,perforin
R5319	T6634	T6633	arg1Of	expression,mRNA
R5320	T6634	T6635	arg1Of	expression,(
R5321	T6638	T6636	arg1Of	B,Fig.
R5322	T6638	T6637	arg1Of	B,2
R5323	T6638	T6640	arg1Of	B,compare
R5324	T6640	T6635	arg2Of	compare,(
R5325	T6640	T6639	arg1Of	compare,","
R5326	T6642	T6643	arg1Of	1,and
R5327	T6643	T6640	arg2Of	and,compare
R5328	T6643	T6641	arg1Of	and,lanes
R5329	T6644	T6643	arg2Of	4,and
R5330	T6645	T6635	arg3Of	),(
R5331	T6646	T6648	arg1Of	We,observed
R5332	T6648	T6647	arg1Of	observed,consistently
R5333	T6648	T6659	arg1Of	observed,(
R5334	T6648	T6670	arg1Of	observed,","
R5335	T6648	T6671	arg1Of	observed,which
R5336	T6648	T6672	arg1Of	observed,did
R5337	T6648	T6674	arg1Of	observed,translate
R5338	T6651	T6648	arg2Of	reduction,observed
R5339	T6651	T6649	arg1Of	reduction,a
R5340	T6651	T6650	arg1Of	reduction,modest
R5341	T6651	T6652	arg1Of	reduction,in
R5342	T6651	T6655	arg1Of	reduction,in
R5343	T6654	T6652	arg2Of	mRNA,in
R5344	T6654	T6653	arg1Of	mRNA,GzmB
R5345	T6658	T6655	arg2Of	cells,in
R5346	T6658	T6656	arg1Of	cells,T-bet–deficient
R5347	T6658	T6657	arg1Of	cells,T
R5348	T6662	T6660	arg1Of	B,Fig.
R5349	T6662	T6661	arg1Of	B,2
R5350	T6662	T6664	arg1Of	B,compare
R5351	T6664	T6659	arg2Of	compare,(
R5352	T6664	T6663	arg1Of	compare,","
R5353	T6666	T6667	arg1Of	1,and
R5354	T6667	T6664	arg2Of	and,compare
R5355	T6667	T6665	arg1Of	and,lanes
R5356	T6668	T6667	arg2Of	4,and
R5357	T6669	T6659	arg3Of	),(
R5358	T6674	T6672	arg2Of	translate,did
R5359	T6674	T6673	arg1Of	translate,not
R5360	T6674	T6675	arg1Of	translate,into
R5361	T6677	T6675	arg2Of	decrease,into
R5362	T6677	T6676	arg1Of	decrease,a
R5363	T6677	T6678	arg1Of	decrease,in
R5364	T6679	T6678	arg2Of	expression,in
R5365	T6679	T6680	arg1Of	expression,of
R5366	T6683	T6680	arg2Of	protein,of
R5367	T6683	T6681	arg1Of	protein,granzyme
R5368	T6683	T6682	arg1Of	protein,B
R5369	T6683	T6684	arg1Of	protein,(
R5370	T6687	T6684	arg2Of	C,(
R5371	T6687	T6685	arg1Of	C,Fig.
R5372	T6687	T6686	arg1Of	C,2
R5373	T6688	T6684	arg3Of	),(
R5374	T6690	T6689	arg1Of	examine,To
R5375	T6692	T6690	arg2Of	role,examine
R5376	T6692	T6691	arg1Of	role,the
R5377	T6692	T6693	arg1Of	role,of
R5378	T6694	T6693	arg2Of	Eomes,of
R5379	T6696	T6697	arg1Of	we,transduced
R5380	T6697	T6689	modOf	transduced,To
R5381	T6697	T6695	arg1Of	transduced,","
R5382	T6701	T6697	arg2Of	cells,transduced
R5383	T6701	T6698	arg1Of	cells,naive
R5384	T6701	T6699	arg1Of	cells,CD8+
R5385	T6701	T6700	arg1Of	cells,T
R5386	T6701	T6702	arg1Of	cells,from
R5387	T6701	T6707	arg1Of	cells,with
R5388	T6703	T6704	arg1Of	WT,and
R5389	T6705	T6704	arg2Of	Tbx21−/−,and
R5390	T6706	T6702	arg2Of	mice,from
R5391	T6706	T6703	arg1Of	mice,WT
R5392	T6706	T6705	arg1Of	mice,Tbx21−/−
R5393	T6708	T6707	arg2Of	retroviruses,with
R5394	T6708	T6709	arg1Of	retroviruses,containing
R5395	T6713	T6710	arg1Of	site,internal
R5396	T6713	T6711	arg1Of	site,ribosome
R5397	T6713	T6712	arg1Of	site,entry
R5398	T6713	T6714	arg1Of	site,(
R5399	T6715	T6714	arg2Of	IRES,(
R5400	T6716	T6714	arg3Of	),(
R5401	T6717	T6709	arg2Of	–GFP,containing
R5402	T6717	T6713	arg1Of	–GFP,site
R5403	T6717	T6718	arg1Of	–GFP,that
R5404	T6717	T6719	arg1Of	–GFP,were
R5405	T6717	T6721	arg1Of	–GFP,empty
R5406	T6717	T6723	arg1Of	–GFP,encoded
R5407	T6717	T6738	arg1Of	–GFP,expanded
R5408	T6719	T6722	arg1Of	were,or
R5409	T6721	T6719	arg2Of	empty,were
R5410	T6721	T6720	arg1Of	empty,either
R5411	T6722	T6737	arg1Of	or,and
R5412	T6723	T6722	arg2Of	encoded,or
R5413	T6726	T6725	arg1Of	transactivating,strongly
R5414	T6727	T6723	arg2Of	version,encoded
R5415	T6727	T6724	arg1Of	version,a
R5416	T6727	T6726	arg1Of	version,transactivating
R5417	T6727	T6728	arg1Of	version,of
R5418	T6729	T6728	arg2Of	Eomes,of
R5419	T6729	T6730	arg1Of	Eomes,(
R5420	T6729	T6733	arg1Of	Eomes,(
R5421	T6731	T6730	arg2Of	Eo-VP16,(
R5422	T6732	T6730	arg3Of	),(
R5423	T6734	T6733	arg2Of	8,(
R5424	T6735	T6733	arg3Of	),(
R5425	T6737	T6736	arg1Of	and,","
R5426	T6738	T6737	arg2Of	expanded,and
R5427	T6738	T6740	arg1Of	expanded,for
R5428	T6738	T6743	arg1Of	expanded,under
R5429	T6739	T6738	arg2Of	them,expanded
R5430	T6742	T6740	arg2Of	d,for
R5431	T6742	T6741	arg1Of	d,6
R5432	T6746	T6743	arg2Of	conditions,under
R5433	T6746	T6744	arg1Of	conditions,our
R5434	T6746	T6745	arg1Of	conditions,culture
R5435	T6747	T6749	arg1Of	Eo-VP16,but
R5436	T6749	T6748	arg1Of	but,","
R5437	T6749	T6750	arg1Of	but,not
R5438	T6749	T6756	arg1Of	but,increased
R5439	T6754	T6749	arg2Of	retrovirus,but
R5440	T6754	T6751	arg1Of	retrovirus,the
R5441	T6754	T6752	arg1Of	retrovirus,empty
R5442	T6754	T6753	arg1Of	retrovirus,GFP
R5443	T6756	T6755	arg1Of	increased,","
R5444	T6758	T6756	arg2Of	expression,increased
R5445	T6758	T6757	arg1Of	expression,perforin
R5446	T6758	T6759	arg1Of	expression,in
R5447	T6766	T6759	arg2Of	cells,in
R5448	T6766	T6760	arg1Of	cells,both
R5449	T6766	T6761	arg1Of	cells,WT
R5450	T6766	T6762	arg1Of	cells,and
R5451	T6766	T6763	arg1Of	cells,T-bet–deficient
R5452	T6766	T6764	arg1Of	cells,CD8+
R5453	T6766	T6765	arg1Of	cells,T
R5454	T6766	T6767	arg1Of	cells,(
R5455	T6770	T6767	arg2Of	B,(
R5456	T6770	T6768	arg1Of	B,Fig.
R5457	T6770	T6769	arg1Of	B,2
R5458	T6770	T6771	arg1Of	B,","
R5459	T6773	T6774	arg1Of	2,","
R5460	T6774	T6776	arg1Of	",",","
R5461	T6775	T6774	arg2Of	3,","
R5462	T6776	T6772	arg1Of	",",lanes
R5463	T6776	T6779	arg1Of	",",and
R5464	T6777	T6776	arg2Of	5,","
R5465	T6779	T6771	arg2Of	and,","
R5466	T6779	T6778	arg1Of	and,","
R5467	T6780	T6779	arg2Of	6,and
R5468	T6781	T6767	arg3Of	),(
R5469	T6783	T6782	arg2Of	expected,As
R5470	T6785	T6787	arg1Of	Eo-VP16,rescued
R5471	T6787	T6782	arg1Of	rescued,As
R5472	T6787	T6784	arg1Of	rescued,","
R5473	T6787	T6786	arg1Of	rescued,also
R5474	T6790	T6787	arg2Of	defect,rescued
R5475	T6790	T6788	arg1Of	defect,the
R5476	T6790	T6789	arg1Of	defect,early
R5477	T6790	T6791	arg1Of	defect,in
R5478	T6793	T6791	arg2Of	production,in
R5479	T6793	T6792	arg1Of	production,IFN-γ
R5480	T6793	T6794	arg2Of	production,observed
R5481	T6794	T6795	arg1Of	observed,in
R5482	T6799	T6795	arg2Of	cells,in
R5483	T6799	T6796	arg1Of	cells,T-bet–deficient
R5484	T6799	T6797	arg1Of	cells,CD8+
R5485	T6799	T6798	arg1Of	cells,T
R5486	T6799	T6800	arg1Of	cells,(
R5487	T6803	T6800	arg2Of	D,(
R5488	T6803	T6801	arg1Of	D,Fig.
R5489	T6803	T6802	arg1Of	D,2
R5490	T6804	T6800	arg3Of	),(
R5491	T6807	T6808	arg1Of	Eo-VP16,did
R5492	T6807	T6810	arg1Of	Eo-VP16,induce
R5493	T6810	T6805	arg1Of	induce,However
R5494	T6810	T6806	arg1Of	induce,","
R5495	T6810	T6808	arg2Of	induce,did
R5496	T6810	T6809	arg1Of	induce,not
R5497	T6810	T6820	arg1Of	induce,;
R5498	T6813	T6810	arg2Of	expression,induce
R5499	T6813	T6811	arg1Of	expression,GzmB
R5500	T6813	T6812	arg1Of	expression,mRNA
R5501	T6813	T6814	arg1Of	expression,in
R5502	T6816	T6817	arg1Of	WT,or
R5503	T6817	T6814	arg2Of	or,in
R5504	T6817	T6815	arg1Of	or,either
R5505	T6819	T6817	arg2Of	cells,or
R5506	T6819	T6818	arg1Of	cells,T-bet–deficient
R5507	T6826	T6823	arg1Of	dependence,the
R5508	T6826	T6824	arg1Of	dependence,partial
R5509	T6826	T6825	arg1Of	dependence,T-bet
R5510	T6826	T6827	arg1Of	dependence,of
R5511	T6826	T6831	arg1Of	dependence,can
R5512	T6826	T6833	arg1Of	dependence,be
R5513	T6826	T6834	arg2Of	dependence,compensated
R5514	T6830	T6827	arg2Of	expression,of
R5515	T6830	T6828	arg1Of	expression,GzmB
R5516	T6830	T6829	arg1Of	expression,mRNA
R5517	T6834	T6820	arg2Of	compensated,;
R5518	T6834	T6821	arg1Of	compensated,thus
R5519	T6834	T6822	arg1Of	compensated,","
R5520	T6834	T6831	arg2Of	compensated,can
R5521	T6834	T6832	arg1Of	compensated,not
R5522	T6834	T6833	arg2Of	compensated,be
R5523	T6834	T6835	arg1Of	compensated,for
R5524	T6837	T6834	arg1Of	Eo-VP16,compensated
R5525	T6837	T6836	arg2Of	Eo-VP16,by
R15127	T19474	T19475	arg1Of	Regulation,of
R15128	T19474	T19488	arg1Of	Regulation,in
R15129	T19476	T19477	arg1Of	perforin,","
R15130	T19477	T19481	arg1Of	",",and
R15131	T19479	T19477	arg2Of	B,","
R15132	T19479	T19478	arg1Of	B,granzyme
R15133	T19481	T19475	arg2Of	and,of
R15134	T19481	T19480	arg1Of	and,","
R15135	T19481	T19484	arg1Of	and,by
R15136	T19483	T19481	arg2Of	expression,and
R15137	T19483	T19482	arg1Of	expression,IFN-γ
R15138	T19485	T19486	arg1Of	T-bet,and
R15139	T19486	T19484	arg2Of	and,by
R15140	T19487	T19486	arg2Of	Eomes,and
R15141	T19489	T19488	arg2Of	differentiating,in
R15142	T19489	T19496	arg1Of	differentiating,by
R15143	T19490	T19491	arg1Of	CTLs.,(
R15144	T19492	T19491	arg2Of	A,(
R15145	T19493	T19491	arg3Of	),(
R15146	T19495	T19489	arg2Of	expression,differentiating
R15147	T19495	T19490	arg1Of	expression,CTLs.
R15148	T19495	T19494	arg1Of	expression,IFN-γ
R15149	T19497	T19498	arg1Of	WT,(
R15150	T19497	T19501	arg1Of	WT,and
R15151	T19499	T19498	arg2Of	Tbx21+/+,(
R15152	T19500	T19498	arg3Of	),(
R15153	T19501	T19496	arg2Of	and,by
R15154	T19504	T19503	arg2Of	Tbx21−/−,(
R15155	T19505	T19503	arg3Of	),(
R15156	T19507	T19501	arg2Of	cells,and
R15157	T19507	T19502	arg1Of	cells,T-bet–deficient
R15158	T19507	T19503	arg1Of	cells,(
R15159	T19507	T19506	arg1Of	cells,T
R15160	T19511	T19508	arg1Of	cells,Naive
R15161	T19511	T19509	arg1Of	cells,CD8+
R15162	T19511	T19510	arg1Of	cells,T
R15163	T19511	T19513	arg1Of	cells,or
R15164	T19513	T19512	arg1Of	or,","
R15165	T19513	T19524	arg1Of	or,were
R15166	T19513	T19525	arg2Of	or,restimulated
R15167	T19514	T19513	arg2Of	cells,or
R15168	T19514	T19515	arg2Of	cells,activated
R15169	T19514	T19517	arg2Of	cells,cultured
R15170	T19515	T19516	arg1Of	activated,and
R15171	T19517	T19516	arg2Of	cultured,and
R15172	T19517	T19518	arg1Of	cultured,for
R15173	T19519	T19520	arg1Of	4,or
R15174	T19521	T19520	arg2Of	6,or
R15175	T19522	T19518	arg2Of	d,for
R15176	T19522	T19519	arg1Of	d,4
R15177	T19522	T19521	arg1Of	d,6
R15178	T19525	T19523	arg1Of	restimulated,","
R15179	T19525	T19524	arg2Of	restimulated,were
R15180	T19525	T19526	arg1Of	restimulated,with
R15181	T19525	T19530	arg1Of	restimulated,for
R15182	T19525	T19534	arg1Of	restimulated,and
R15183	T19527	T19528	arg1Of	PMA,and
R15184	T19528	T19526	arg2Of	and,with
R15185	T19529	T19528	arg2Of	ionomycin,and
R15186	T19532	T19530	arg2Of	h,for
R15187	T19532	T19531	arg1Of	h,6
R15188	T19534	T19533	arg1Of	and,","
R15189	T19536	T19535	arg1Of	expression,IFN-γ
R15190	T19536	T19537	arg1Of	expression,was
R15191	T19536	T19538	arg2Of	expression,assessed
R15192	T19538	T19534	arg2Of	assessed,and
R15193	T19538	T19537	arg2Of	assessed,was
R15194	T19541	T19538	arg1Of	staining,assessed
R15195	T19541	T19539	arg2Of	staining,by
R15196	T19541	T19540	arg1Of	staining,intracellular
R15197	T19542	T19543	arg1Of	Numbers,show
R15198	T19545	T19543	arg2Of	percentage,show
R15199	T19545	T19544	arg1Of	percentage,the
R15200	T19545	T19546	arg1Of	percentage,of
R15201	T19545	T19549	arg1Of	percentage,(
R15202	T19548	T19546	arg2Of	cells.,of
R15203	T19548	T19547	arg1Of	cells.,IFN-γ+
R15204	T19550	T19549	arg2Of	B,(
R15205	T19551	T19549	arg3Of	),(
R15206	T19554	T19543	arg3Of	analysis,show
R15207	T19554	T19552	arg1Of	analysis,Northern
R15208	T19554	T19553	arg1Of	analysis,blot
R15209	T19554	T19555	arg1Of	analysis,of
R15210	T19556	T19557	arg1Of	Prf1,and
R15211	T19558	T19557	arg2Of	GzmB,and
R15212	T19560	T19555	arg2Of	expression,of
R15213	T19560	T19556	arg1Of	expression,Prf1
R15214	T19560	T19558	arg1Of	expression,GzmB
R15215	T19560	T19559	arg1Of	expression,mRNA
R15216	T19560	T19561	arg1Of	expression,in
R15217	T19562	T19563	arg1Of	WT,or
R15218	T19564	T19563	arg2Of	T-bet–deficient,or
R15219	T19567	T19561	arg2Of	cells,in
R15220	T19567	T19562	arg1Of	cells,WT
R15221	T19567	T19564	arg1Of	cells,T-bet–deficient
R15222	T19567	T19565	arg1Of	cells,CD8+
R15223	T19567	T19566	arg1Of	cells,T
R15224	T19567	T19568	arg2Of	cells,activated
R15225	T19567	T19572	arg1Of	cells,uninfected
R15226	T19567	T19577	arg2Of	cells,transduced
R15227	T19568	T19569	arg1Of	activated,and
R15228	T19569	T19576	arg1Of	and,or
R15229	T19572	T19569	arg2Of	uninfected,and
R15230	T19572	T19570	arg1Of	uninfected,either
R15231	T19572	T19571	arg1Of	uninfected,left
R15232	T19572	T19573	arg1Of	uninfected,(
R15233	T19574	T19573	arg2Of	uninf,(
R15234	T19575	T19573	arg3Of	),(
R15235	T19577	T19576	arg2Of	transduced,or
R15236	T19577	T19578	arg1Of	transduced,with
R15237	T19579	T19578	arg2Of	retroviruses,with
R15238	T19579	T19580	arg1Of	retroviruses,expressing
R15239	T19581	T19582	arg1Of	Eomes-VP16,(
R15240	T19581	T19585	arg1Of	Eomes-VP16,or
R15241	T19583	T19582	arg2Of	Eo-VP16,(
R15242	T19584	T19582	arg3Of	),(
R15243	T19585	T19580	arg2Of	or,expressing
R15244	T19589	T19585	arg2Of	cassette,or
R15245	T19589	T19586	arg1Of	cassette,an
R15246	T19589	T19587	arg1Of	cassette,empty
R15247	T19589	T19588	arg1Of	cassette,IRES-GFP
R15248	T19589	T19590	arg1Of	cassette,(
R15249	T19591	T19590	arg2Of	GFP,(
R15250	T19592	T19590	arg3Of	),(
R15251	T19595	T19593	arg1Of	RNA,Total
R15252	T19595	T19594	arg1Of	RNA,cellular
R15253	T19595	T19596	arg1Of	RNA,was
R15254	T19595	T19597	arg2Of	RNA,analyzed
R15255	T19597	T19596	arg2Of	analyzed,was
R15256	T19597	T19598	arg1Of	analyzed,on
R15257	T19599	T19598	arg2Of	day,on
R15258	T19599	T19600	arg1Of	day,6
R15259	T19599	T19601	arg1Of	day,of
R15260	T19602	T19601	arg2Of	culture,of
R15261	T19604	T19603	arg1Of	frequency,The
R15262	T19604	T19605	arg1Of	frequency,of
R15263	T19604	T19608	arg1Of	frequency,in
R15264	T19604	T19611	arg1Of	frequency,was
R15265	T19604	T19612	arg1Of	frequency,equivalent
R15266	T19607	T19605	arg2Of	cells,of
R15267	T19607	T19606	arg2Of	cells,transduced
R15268	T19610	T19608	arg2Of	cultures,in
R15269	T19610	T19609	arg1Of	cultures,the
R15270	T19612	T19611	arg2Of	equivalent,was
R15271	T19612	T19613	arg1Of	equivalent,for
R15272	T19615	T19613	arg2Of	constructs,for
R15273	T19615	T19614	arg1Of	constructs,both
R15274	T19617	T19618	arg1Of	∼65–70,%
R15275	T19620	T19616	arg2Of	cells,(
R15276	T19620	T19617	arg1Of	cells,∼65–70
R15277	T19620	T19619	arg1Of	cells,GFP+
R15278	T19626	T19625	arg2Of	(,.
R15279	T19627	T19625	arg3Of	C,.
R15280	T19629	T19628	arg1Of	m,) Granzy
R15281	T19629	T19630	arg1Of	m,e B
R15282	T19630	T19625	arg1Of	e B,.
R15283	T19632	T19630	arg2Of	FN-γ expre,e B
R15284	T19632	T19631	arg1Of	FN-γ expre,and I
R15285	T19634	T19635	arg1Of	ion by T,bx2
R15286	T19636	T19635	arg2Of	1+/+ and,bx2
R15287	T19638	T19633	arg2Of	bx21−,ss
R15288	T19638	T19634	arg1Of	bx21−,ion by T
R15289	T19638	T19636	arg1Of	bx21−,1+/+ and
R15290	T19638	T19637	arg1Of	bx21−,T
R15291	T19638	T19639	arg2Of	bx21−,/− T cel
R15292	T19638	T19643	arg1Of	bx21−,mula
R15293	T19638	T19644	arg1Of	bx21−,ted
R15294	T19638	T19645	arg1Of	bx21−,cell
R15295	T19638	T19646	arg2Of	bx21−,s that h
R15296	T19639	T19640	arg1Of	/− T cel,ls
R15297	T19642	T19640	arg2Of	resti,ls
R15298	T19642	T19641	arg2Of	resti,analyzed in
R15299	T19646	T19644	arg2Of	s that h,ted
R15300	T19646	T19645	arg2Of	s that h,cell
R15301	T19646	T19647	arg1Of	s that h,ad
R15302	T19649	T19648	arg1Of	ee,b
R15303	T19649	T19650	arg1Of	ee,n
R15304	T19651	T19650	arg2Of	c,n
R15305	T19652	T19650	arg3Of	u,n
R15306	T19654	T19647	arg2Of	d for 5 d.,ad
R15307	T19654	T19649	arg1Of	d for 5 d.,ee
R15308	T19654	T19653	arg1Of	d for 5 d.,lture
R15309	T19656	T19655	arg2Of	) IFN,(D
R15310	T19656	T19657	arg2Of	) IFN,-γ product
R15311	T19657	T19658	arg1Of	-γ product,ion
R15312	T19659	T19660	arg1Of	by cell,s
R15313	T19660	T19658	arg2Of	s ,ion
R15314	T19663	T19662	arg2Of	ed ,c
R15315	T19664	T19662	arg3Of	w,c
R15316	T19665	T19660	arg2Of	ith Eo-VP16 ,s
R15317	T19665	T19661	arg1Of	ith Eo-VP16 ,transdu
R15318	T19665	T19662	arg1Of	ith Eo-VP16 ,c
R15319	T19665	T19666	arg1Of	ith Eo-VP16 ,o
R15320	T19665	T19669	arg2Of	ith Eo-VP16 ,ontrol (
R15321	T19667	T19666	arg2Of	r ,o
R15322	T19668	T19666	arg3Of	c,o
R15323	T19669	T19670	arg1Of	ontrol (,GF
R15324	T19669	T19673	arg1Of	ontrol (,etrov
R15325	T19671	T19670	arg2Of	P) ,GF
R15326	T19671	T19672	arg1Of	P) ,r
R15327	T19675	T19673	arg2Of	r,etrov
R15328	T19675	T19674	arg1Of	r,i
R15329	T19675	T19676	arg1Of	r,us
R15330	T19677	T19676	arg2Of	es (RV) measu,us
R15331	T19677	T19678	arg1Of	es (RV) measu,red
R15332	T19679	T19680	arg1Of	on ,day
R15333	T19680	T19678	arg2Of	day,red
R15334	T19681	T19680	arg2Of	4 after 6,day
R15335	T19682	T19683	arg1Of	Numbers,show
R15336	T19685	T19683	arg2Of	percentage,show
R15337	T19685	T19684	arg1Of	percentage,the
R15338	T19685	T19686	arg1Of	percentage,of
R15339	T19689	T19686	arg2Of	cells,of
R15340	T19689	T19687	arg1Of	cells,GFP+
R15341	T19689	T19688	arg1Of	cells,IFN-γ+
R15342	T19690	T19691	arg1Of	Results,are
R15343	T19690	T19692	arg1Of	Results,representative
R15344	T19692	T19691	arg2Of	representative,are
R15345	T19692	T19693	arg1Of	representative,of
R15346	T19694	T19695	arg1Of	three,(
R15347	T19694	T19700	arg1Of	three,or
R15348	T19696	T19697	arg1Of	A,and
R15349	T19697	T19695	arg2Of	and,(
R15350	T19698	T19697	arg2Of	C,and
R15351	T19699	T19695	arg3Of	),(
R15352	T19700	T19702	arg1Of	or,(
R15353	T19701	T19700	arg2Of	two,or
R15354	T19703	T19704	arg1Of	B,and
R15355	T19704	T19702	arg2Of	and,(
R15356	T19705	T19704	arg2Of	D,and
R15357	T19706	T19702	arg3Of	),(
R15358	T19708	T19693	arg2Of	experiments,of
R15359	T19708	T19694	arg1Of	experiments,three
R15360	T19708	T19701	arg1Of	experiments,two
R15361	T19708	T19707	arg1Of	experiments,independent

bionlp-st-ge-2016-coref

Id	Subject	Object	Predicate	Lexical cue
T6838	590-595	Anaphor	denotes	which
T6839	583-588	Antecedent	denotes	Eomes
R5526	T6838	T6839	boundBy	which,Eomes

bionlp-st-ge-2016-spacy-parsed

Id	Subject	Object	Predicate	Lexical cue
T6120	0-8	NNP	denotes	Perforin
T6121	9-12	CC	denotes	and
T6122	13-21	NN	denotes	granzyme
T6123	22-23	NNP	denotes	B
T6124	24-34	NN	denotes	expression
T6125	35-38	VBP	denotes	are
T6126	39-42	RB	denotes	not
T6127	43-54	RB	denotes	appreciably
T6128	55-64	VBN	denotes	regulated
T6129	65-67	IN	denotes	by
T6130	68-73	NNP	denotes	T-bet
T6131	74-76	TO	denotes	To
T6132	77-81	VB	denotes	test
T6133	82-85	DT	denotes	the
T6134	86-91	NN	denotes	model
T6135	92-100	VBN	denotes	outlined
T6136	101-103	IN	denotes	in
T6137	104-107	DT	denotes	the
T6138	108-116	JJ	denotes	previous
T6139	117-126	NN	denotes	paragraph
T6140	127-135	RB	denotes	directly
T6141	135-136	,	denotes	,
T6142	137-139	PRP	denotes	we
T6143	140-148	VBD	denotes	compared
T6144	149-152	DT	denotes	the
T6145	153-163	NN	denotes	expression
T6146	164-166	IN	denotes	of
T6147	167-172	NNP	denotes	IFN-γ
T6148	172-173	,	denotes	,
T6149	174-182	NN	denotes	perforin
T6150	182-183	,	denotes	,
T6151	184-187	CC	denotes	and
T6152	188-196	NN	denotes	granzyme
T6153	197-198	NN	denotes	B
T6154	199-201	IN	denotes	in
T6155	202-205	CD	denotes	CD8
T6156	205-206	CD	denotes	+
T6157	207-208	NNP	denotes	T
T6158	209-214	NNS	denotes	cells
T6159	215-219	IN	denotes	from
T6160	220-222	NNP	denotes	WT
T6161	223-226	CC	denotes	and
T6162	227-232	NNP	denotes	Tbx21
T6163	233-234	-LRB-	denotes	(
T6164	234-239	NNP	denotes	T-bet
T6165	239-240	-RRB-	denotes	)
T6166	240-241	:	denotes	-
T6167	241-250	NN	denotes	deficient
T6168	251-255	NNS	denotes	mice
T6169	255-256	.	denotes	.
T6170	257-259	IN	denotes	As
T6171	260-268	VBN	denotes	expected
T6172	269-270	-LRB-	denotes	(
T6173	270-272	CD	denotes	17
T6174	272-273	,	denotes	,
T6175	274-276	CD	denotes	21
T6176	276-277	-RRB-	denotes	)
T6177	277-278	,	denotes	,
T6178	279-284	JJ	denotes	naive
T6179	285-290	NNP	denotes	Tbx21
T6180	290-291	FW	denotes	−
T6181	291-292	FW	denotes	/
T6182	292-293	FW	denotes	−
T6183	294-297	FW	denotes	CD8
T6184	297-298	FW	denotes	+
T6185	299-300	FW	denotes	T
T6186	301-306	NNS	denotes	cells
T6187	307-315	VBD	denotes	produced
T6188	316-321	JJ	denotes	IFN-γ
T6189	322-328	RB	denotes	poorly
T6190	329-333	IN	denotes	upon
T6191	334-344	NN	denotes	activation
T6192	345-346	-LRB-	denotes	(
T6193	346-350	JJ	denotes	Fig.
T6194	351-352	CD	denotes	2
T6195	353-354	NN	denotes	A
T6196	354-355	-RRB-	denotes	)
T6197	355-356	.	denotes	.
T6198	357-364	RB	denotes	Notably
T6199	364-365	,	denotes	,
T6200	366-370	DT	denotes	this
T6201	371-382	JJ	denotes	deleterious
T6202	383-389	NN	denotes	effect
T6203	390-392	IN	denotes	of
T6204	393-398	NN	denotes	T-bet
T6205	399-409	NN	denotes	deficiency
T6206	410-413	VBD	denotes	was
T6207	414-418	RB	denotes	only
T6208	419-427	VBN	denotes	observed
T6209	428-430	IN	denotes	in
T6210	431-446	VBG	denotes	differentiating
T6211	447-450	NNP	denotes	CD8
T6212	450-451	CD	denotes	+
T6213	452-453	NNP	denotes	T
T6214	454-459	NNS	denotes	cells
T6215	460-465	IN	denotes	until
T6216	466-469	NN	denotes	day
T6217	470-471	CD	denotes	4
T6218	472-474	IN	denotes	of
T6219	475-482	NN	denotes	culture
T6220	483-486	CC	denotes	but
T6221	487-490	VBD	denotes	was
T6222	491-497	RB	denotes	almost
T6223	498-508	RB	denotes	completely
T6224	509-518	VBN	denotes	mitigated
T6225	519-521	IN	denotes	by
T6226	522-525	NN	denotes	day
T6227	526-527	CD	denotes	6
T6228	528-529	-LRB-	denotes	(
T6229	529-533	NN	denotes	Fig.
T6230	534-535	CD	denotes	2
T6231	536-537	NNP	denotes	A
T6232	537-538	-RRB-	denotes	)
T6233	538-539	.	denotes	.
T6234	540-544	DT	denotes	This
T6235	545-549	RBS	denotes	most
T6236	550-556	JJ	denotes	likely
T6237	557-566	VBN	denotes	reflected
T6238	567-579	NN	denotes	compensation
T6239	580-582	IN	denotes	by
T6240	583-588	NNP	denotes	Eomes
T6241	588-589	,	denotes	,
T6242	590-595	WDT	denotes	which
T6243	596-599	VBD	denotes	was
T6244	600-608	RB	denotes	strongly
T6245	609-616	JJ	denotes	induced
T6246	617-624	IN	denotes	between
T6247	625-629	NNS	denotes	days
T6248	630-631	CD	denotes	4
T6249	632-635	CC	denotes	and
T6250	636-637	CD	denotes	6
T6251	638-639	-LRB-	denotes	(
T6252	639-643	NN	denotes	Fig.
T6253	644-645	CD	denotes	1
T6254	645-646	-RRB-	denotes	)
T6255	646-647	.	denotes	.
T6256	648-650	IN	denotes	In
T6257	651-659	NN	denotes	contrast
T6258	659-660	,	denotes	,
T6259	661-666	NNP	denotes	T-bet
T6260	667-676	JJ	denotes	deficient
T6261	677-678	NNP	denotes	T
T6262	679-684	NNS	denotes	cells
T6263	685-693	VBD	denotes	cultured
T6264	694-697	IN	denotes	for
T6265	698-699	CD	denotes	6
T6266	700-701	LS	denotes	d
T6267	702-708	VBD	denotes	showed
T6268	709-711	DT	denotes	no
T6269	712-718	NN	denotes	defect
T6270	719-721	IN	denotes	in
T6271	722-730	NN	denotes	perforin
T6272	731-735	NNP	denotes	mRNA
T6273	736-746	NN	denotes	expression
T6274	747-748	-LRB-	denotes	(
T6275	748-752	JJ	denotes	Fig.
T6276	753-754	CD	denotes	2
T6277	755-756	NNP	denotes	B
T6278	756-757	,	denotes	,
T6279	758-765	VBP	denotes	compare
T6280	766-771	NNS	denotes	lanes
T6281	772-773	CD	denotes	1
T6282	774-777	CC	denotes	and
T6283	778-779	CD	denotes	4
T6284	779-780	-RRB-	denotes	)
T6285	780-781	.	denotes	.
T6286	782-784	PRP	denotes	We
T6287	785-797	RB	denotes	consistently
T6288	798-806	VBD	denotes	observed
T6289	807-808	DT	denotes	a
T6290	809-815	JJ	denotes	modest
T6291	816-825	NN	denotes	reduction
T6292	826-828	IN	denotes	in
T6293	829-833	NNP	denotes	GzmB
T6294	834-838	NNP	denotes	mRNA
T6295	839-841	IN	denotes	in
T6296	842-847	NNP	denotes	T-bet
T6297	848-857	JJ	denotes	deficient
T6298	858-859	NNP	denotes	T
T6299	860-865	NNS	denotes	cells
T6300	866-867	-LRB-	denotes	(
T6301	867-871	NN	denotes	Fig.
T6302	872-873	CD	denotes	2
T6303	874-875	NNP	denotes	B
T6304	875-876	,	denotes	,
T6305	877-884	VBP	denotes	compare
T6306	885-890	NNS	denotes	lanes
T6307	891-892	CD	denotes	1
T6308	893-896	CC	denotes	and
T6309	897-898	CD	denotes	4
T6310	898-899	-RRB-	denotes	)
T6311	899-900	,	denotes	,
T6312	901-906	WDT	denotes	which
T6313	907-910	VBD	denotes	did
T6314	911-914	RB	denotes	not
T6315	915-924	VB	denotes	translate
T6316	925-929	IN	denotes	into
T6317	930-931	DT	denotes	a
T6318	932-940	NN	denotes	decrease
T6319	941-943	IN	denotes	in
T6320	944-954	NN	denotes	expression
T6321	955-957	IN	denotes	of
T6322	958-966	NN	denotes	granzyme
T6323	967-968	NNP	denotes	B
T6324	969-976	NN	denotes	protein
T6325	977-978	-LRB-	denotes	(
T6326	978-982	JJ	denotes	Fig.
T6327	983-984	CD	denotes	2
T6328	985-986	NNP	denotes	C
T6329	986-987	-RRB-	denotes	)
T6330	987-988	.	denotes	.
T6331	2245-2247	TO	denotes	To
T6332	2248-2255	VB	denotes	examine
T6333	2256-2259	DT	denotes	the
T6334	2260-2264	NN	denotes	role
T6335	2265-2267	IN	denotes	of
T6336	2268-2273	NNP	denotes	Eomes
T6337	2273-2274	,	denotes	,
T6338	2275-2277	PRP	denotes	we
T6339	2278-2288	VBD	denotes	transduced
T6340	2289-2294	JJ	denotes	naive
T6341	2295-2298	NNP	denotes	CD8
T6342	2298-2299	CD	denotes	+
T6343	2300-2301	NNP	denotes	T
T6344	2302-2307	NNS	denotes	cells
T6345	2308-2312	IN	denotes	from
T6346	2313-2315	NNP	denotes	WT
T6347	2316-2319	CC	denotes	and
T6348	2320-2325	NNP	denotes	Tbx21
T6349	2325-2326	NNP	denotes	−
T6350	2326-2327	VBD	denotes	/
T6351	2327-2328	CD	denotes	−
T6352	2329-2333	NNS	denotes	mice
T6353	2334-2338	IN	denotes	with
T6354	2339-2351	NNS	denotes	retroviruses
T6355	2352-2362	VBG	denotes	containing
T6356	2363-2371	JJ	denotes	internal
T6357	2372-2380	JJ	denotes	ribosome
T6358	2381-2386	NN	denotes	entry
T6359	2387-2391	NN	denotes	site
T6360	2392-2393	-LRB-	denotes	(
T6361	2393-2397	NNP	denotes	IRES
T6362	2397-2398	-RRB-	denotes	)
T6363	2399-2402	NNP	denotes	GFP
T6364	2403-2407	WDT	denotes	that
T6365	2408-2412	VBD	denotes	were
T6366	2413-2419	CC	denotes	either
T6367	2420-2425	JJ	denotes	empty
T6368	2426-2428	CC	denotes	or
T6369	2429-2436	VBD	denotes	encoded
T6370	2437-2438	DT	denotes	a
T6371	2439-2447	RB	denotes	strongly
T6372	2448-2463	VBG	denotes	transactivating
T6373	2464-2471	NN	denotes	version
T6374	2472-2474	IN	denotes	of
T6375	2475-2480	NNP	denotes	Eomes
T6376	2481-2482	-LRB-	denotes	(
T6377	2482-2489	NNP	denotes	Eo-VP16
T6378	2489-2490	-RRB-	denotes	)
T6379	2491-2492	-LRB-	denotes	(
T6380	2492-2493	CD	denotes	8
T6381	2493-2494	-RRB-	denotes	)
T6382	2494-2495	,	denotes	,
T6383	2496-2499	CC	denotes	and
T6384	2500-2508	VBD	denotes	expanded
T6385	2509-2513	PRP	denotes	them
T6386	2514-2517	IN	denotes	for
T6387	2518-2519	CD	denotes	6
T6388	2520-2521	LS	denotes	d
T6389	2522-2527	IN	denotes	under
T6390	2528-2531	PRP$	denotes	our
T6391	2532-2539	NN	denotes	culture
T6392	2540-2550	NNS	denotes	conditions
T6393	2550-2551	.	denotes	.
T6394	2552-2559	NN	denotes	Eo-VP16
T6395	2559-2560	,	denotes	,
T6396	2561-2564	CC	denotes	but
T6397	2565-2568	RB	denotes	not
T6398	2569-2572	DT	denotes	the
T6399	2573-2578	JJ	denotes	empty
T6400	2579-2582	NNP	denotes	GFP
T6401	2583-2593	NN	denotes	retrovirus
T6402	2593-2594	,	denotes	,
T6403	2595-2604	VBD	denotes	increased
T6404	2605-2613	NN	denotes	perforin
T6405	2614-2624	NN	denotes	expression
T6406	2625-2627	IN	denotes	in
T6407	2628-2632	DT	denotes	both
T6408	2633-2635	NNP	denotes	WT
T6409	2636-2639	CC	denotes	and
T6410	2640-2645	NNP	denotes	T-bet
T6411	2646-2655	JJ	denotes	deficient
T6412	2656-2659	NNP	denotes	CD8
T6413	2659-2660	CD	denotes	+
T6414	2661-2662	NNP	denotes	T
T6415	2663-2668	NNS	denotes	cells
T6416	2669-2670	-LRB-	denotes	(
T6417	2670-2674	NN	denotes	Fig.
T6418	2675-2676	CD	denotes	2
T6419	2677-2678	NNP	denotes	B
T6420	2678-2679	,	denotes	,
T6421	2680-2685	NNS	denotes	lanes
T6422	2686-2687	CD	denotes	2
T6423	2687-2688	,	denotes	,
T6424	2689-2690	CD	denotes	3
T6425	2690-2691	,	denotes	,
T6426	2692-2693	CD	denotes	5
T6427	2693-2694	,	denotes	,
T6428	2695-2698	CC	denotes	and
T6429	2699-2700	CD	denotes	6
T6430	2700-2701	-RRB-	denotes	)
T6431	2701-2702	.	denotes	.
T6432	2703-2705	IN	denotes	As
T6433	2706-2714	VBN	denotes	expected
T6434	2714-2715	,	denotes	,
T6435	2716-2723	NNP	denotes	Eo-VP16
T6436	2724-2728	RB	denotes	also
T6437	2729-2736	VBD	denotes	rescued
T6438	2737-2740	DT	denotes	the
T6439	2741-2746	JJ	denotes	early
T6440	2747-2753	NN	denotes	defect
T6441	2754-2756	IN	denotes	in
T6442	2757-2762	JJ	denotes	IFN-γ
T6443	2763-2773	NN	denotes	production
T6444	2774-2782	VBD	denotes	observed
T6445	2783-2785	IN	denotes	in
T6446	2786-2791	NNP	denotes	T-bet
T6447	2792-2801	JJ	denotes	deficient
T6448	2802-2805	NNP	denotes	CD8
T6449	2805-2806	CD	denotes	+
T6450	2807-2808	NNP	denotes	T
T6451	2809-2814	NNS	denotes	cells
T6452	2815-2816	-LRB-	denotes	(
T6453	2816-2820	NN	denotes	Fig.
T6454	2821-2822	CD	denotes	2
T6455	2823-2824	NNP	denotes	D
T6456	2824-2825	-RRB-	denotes	)
T6457	2825-2826	.	denotes	.
T6458	2827-2834	RB	denotes	However
T6459	2834-2835	,	denotes	,
T6460	2836-2843	NN	denotes	Eo-VP16
T6461	2844-2847	VBD	denotes	did
T6462	2848-2851	RB	denotes	not
T6463	2852-2858	VB	denotes	induce
T6464	2859-2863	NNP	denotes	GzmB
T6465	2864-2868	NNP	denotes	mRNA
T6466	2869-2879	NN	denotes	expression
T6467	2880-2882	IN	denotes	in
T6468	2883-2889	CC	denotes	either
T6469	2890-2892	NNP	denotes	WT
T6470	2893-2895	CC	denotes	or
T6471	2896-2901	NNP	denotes	T-bet
T6472	2902-2911	JJ	denotes	deficient
T6473	2912-2917	NNS	denotes	cells
T6474	2917-2918	:	denotes	;
T6475	2919-2923	RB	denotes	thus
T6476	2923-2924	,	denotes	,
T6477	2925-2928	DT	denotes	the
T6478	2929-2936	JJ	denotes	partial
T6479	2937-2942	NN	denotes	T-bet
T6480	2943-2953	NN	denotes	dependence
T6481	2954-2956	IN	denotes	of
T6482	2957-2961	NNP	denotes	GzmB
T6483	2962-2966	NNP	denotes	mRNA
T6484	2967-2977	NN	denotes	expression
T6485	2978-2981	MD	denotes	can
T6486	2981-2984	RB	denotes	not
T6487	2985-2987	VB	denotes	be
T6488	2988-2999	VBN	denotes	compensated
T6489	3000-3003	IN	denotes	for
T6490	3004-3006	IN	denotes	by
T6491	3007-3014	NN	denotes	Eo-VP16
T6492	3014-3015	.	denotes	.
T19207	999-1009	NN	denotes	Regulation
T19208	1010-1012	IN	denotes	of
T19209	1013-1021	NN	denotes	perforin
T19210	1021-1022	,	denotes	,
T19211	1023-1031	NN	denotes	granzyme
T19212	1032-1033	NNP	denotes	B
T19213	1033-1034	,	denotes	,
T19214	1035-1038	CC	denotes	and
T19215	1039-1044	NNP	denotes	IFN-γ
T19216	1045-1055	NN	denotes	expression
T19217	1056-1058	IN	denotes	by
T19218	1059-1064	NNP	denotes	T-bet
T19219	1065-1068	CC	denotes	and
T19220	1069-1074	NNP	denotes	Eomes
T19221	1075-1077	IN	denotes	in
T19222	1078-1093	VBG	denotes	differentiating
T19223	1094-1098	NNS	denotes	CTLs
T19224	1098-1099	.	denotes	.
T19225	1100-1101	-LRB-	denotes	(
T19226	1101-1102	NNP	denotes	A
T19227	1102-1103	-RRB-	denotes	)
T19228	1104-1109	JJ	denotes	IFN-γ
T19229	1110-1120	NN	denotes	expression
T19230	1121-1123	IN	denotes	by
T19231	1124-1126	NNP	denotes	WT
T19232	1127-1128	-LRB-	denotes	(
T19233	1128-1133	NNP	denotes	Tbx21
T19234	1133-1134	CD	denotes	+
T19235	1134-1135	CD	denotes	/
T19236	1135-1136	NN	denotes	+
T19237	1136-1137	-RRB-	denotes	)
T19238	1138-1141	CC	denotes	and
T19239	1142-1147	NNP	denotes	T-bet
T19240	1148-1157	NN	denotes	deficient
T19241	1158-1159	-LRB-	denotes	(
T19242	1159-1164	CD	denotes	Tbx21
T19243	1164-1165	CD	denotes	−
T19244	1165-1166	NN	denotes	/
T19245	1166-1167	NN	denotes	−
T19246	1167-1168	-RRB-	denotes	)
T19247	1169-1170	NN	denotes	T
T19248	1171-1176	NNS	denotes	cells
T19249	1176-1177	.	denotes	.
T19250	1178-1183	JJ	denotes	Naive
T19251	1184-1187	NNP	denotes	CD8
T19252	1187-1188	CD	denotes	+
T19253	1189-1190	NNP	denotes	T
T19254	1191-1196	NNS	denotes	cells
T19255	1196-1197	,	denotes	,
T19256	1198-1200	CC	denotes	or
T19257	1201-1206	NNS	denotes	cells
T19258	1207-1216	VBN	denotes	activated
T19259	1217-1220	CC	denotes	and
T19260	1221-1229	VBN	denotes	cultured
T19261	1230-1233	IN	denotes	for
T19262	1234-1235	CD	denotes	4
T19263	1236-1238	CC	denotes	or
T19264	1239-1240	CD	denotes	6
T19265	1241-1242	LS	denotes	d
T19266	1242-1243	,	denotes	,
T19267	1244-1248	VBD	denotes	were
T19268	1249-1261	VBN	denotes	restimulated
T19269	1262-1266	IN	denotes	with
T19270	1267-1270	NNP	denotes	PMA
T19271	1271-1274	CC	denotes	and
T19272	1275-1284	NN	denotes	ionomycin
T19273	1285-1288	IN	denotes	for
T19274	1289-1290	CD	denotes	6
T19275	1291-1292	NN	denotes	h
T19276	1292-1293	,	denotes	,
T19277	1294-1297	CC	denotes	and
T19278	1298-1303	NNP	denotes	IFN-γ
T19279	1304-1314	NN	denotes	expression
T19280	1315-1318	VBD	denotes	was
T19281	1319-1327	VBN	denotes	assessed
T19282	1328-1330	IN	denotes	by
T19283	1331-1344	JJ	denotes	intracellular
T19284	1345-1353	NN	denotes	staining
T19285	1353-1354	.	denotes	.
T19286	1355-1362	NNS	denotes	Numbers
T19287	1363-1367	VBP	denotes	show
T19288	1368-1371	DT	denotes	the
T19289	1372-1382	NN	denotes	percentage
T19290	1383-1385	IN	denotes	of
T19291	1386-1391	JJ	denotes	IFN-γ
T19292	1391-1392	NN	denotes	+
T19293	1393-1398	NNS	denotes	cells
T19294	1398-1399	.	denotes	.
T19295	1400-1401	-LRB-	denotes	(
T19296	1401-1402	NNP	denotes	B
T19297	1402-1403	-RRB-	denotes	)
T19298	1404-1412	NNP	denotes	Northern
T19299	1413-1417	NN	denotes	blot
T19300	1418-1426	NN	denotes	analysis
T19301	1427-1429	IN	denotes	of
T19302	1430-1434	NNP	denotes	Prf1
T19303	1435-1438	CC	denotes	and
T19304	1439-1443	NNP	denotes	GzmB
T19305	1444-1448	NNP	denotes	mRNA
T19306	1449-1459	NN	denotes	expression
T19307	1460-1462	IN	denotes	in
T19308	1463-1465	NNP	denotes	WT
T19309	1466-1468	CC	denotes	or
T19310	1469-1474	NNP	denotes	T-bet
T19311	1475-1484	JJ	denotes	deficient
T19312	1485-1488	NNP	denotes	CD8
T19313	1488-1489	CD	denotes	+
T19314	1490-1491	NNP	denotes	T
T19315	1492-1497	NNS	denotes	cells
T19316	1498-1507	VBN	denotes	activated
T19317	1508-1511	CC	denotes	and
T19318	1512-1518	RB	denotes	either
T19319	1519-1523	VBD	denotes	left
T19320	1524-1534	JJ	denotes	uninfected
T19321	1535-1536	-LRB-	denotes	(
T19322	1536-1541	JJ	denotes	uninf
T19323	1541-1542	-RRB-	denotes	)
T19324	1543-1545	CC	denotes	or
T19325	1546-1556	VBN	denotes	transduced
T19326	1557-1561	IN	denotes	with
T19327	1562-1574	NNS	denotes	retroviruses
T19328	1575-1585	VBG	denotes	expressing
T19329	1586-1596	NNP	denotes	Eomes-VP16
T19330	1597-1598	-LRB-	denotes	(
T19331	1598-1605	NNP	denotes	Eo-VP16
T19332	1605-1606	-RRB-	denotes	)
T19333	1607-1609	CC	denotes	or
T19334	1610-1612	DT	denotes	an
T19335	1613-1618	JJ	denotes	empty
T19336	1619-1627	NNP	denotes	IRES-GFP
T19337	1628-1636	NN	denotes	cassette
T19338	1637-1638	-LRB-	denotes	(
T19339	1638-1641	NNP	denotes	GFP
T19340	1641-1642	-RRB-	denotes	)
T19341	1642-1643	.	denotes	.
T19342	1644-1649	JJ	denotes	Total
T19343	1650-1658	JJ	denotes	cellular
T19344	1659-1662	NNP	denotes	RNA
T19345	1663-1666	VBD	denotes	was
T19346	1667-1675	VBN	denotes	analyzed
T19347	1676-1678	IN	denotes	on
T19348	1679-1682	NN	denotes	day
T19349	1683-1684	CD	denotes	6
T19350	1685-1687	IN	denotes	of
T19351	1688-1695	NN	denotes	culture
T19352	1695-1696	.	denotes	.
T19353	1697-1700	DT	denotes	The
T19354	1701-1710	NN	denotes	frequency
T19355	1711-1713	IN	denotes	of
T19356	1714-1724	JJ	denotes	transduced
T19357	1725-1730	NNS	denotes	cells
T19358	1731-1733	IN	denotes	in
T19359	1734-1737	DT	denotes	the
T19360	1738-1746	NNS	denotes	cultures
T19361	1747-1750	VBD	denotes	was
T19362	1751-1761	JJ	denotes	equivalent
T19363	1762-1765	IN	denotes	for
T19364	1766-1770	DT	denotes	both
T19365	1771-1781	NNS	denotes	constructs
T19366	1782-1783	-LRB-	denotes	(
T19367	1783-1784	CD	denotes	∼
T19368	1784-1786	CD	denotes	65
T19369	1787-1789	CD	denotes	70
T19370	1789-1790	NN	denotes	%
T19371	1791-1794	NNP	denotes	GFP
T19372	1794-1795	CD	denotes	+
T19373	1796-1801	NNS	denotes	cells
T19374	1801-1802	:	denotes	;
T19375	1803-1806	RB	denotes	not
T19376	1807-1815	VBN	denotes	depicted
T19377	1815-1816	-RRB-	denotes	)
T19378	1816-1817	.	denotes	.
T19379	1818-1819	-LRB-	denotes	(
T19380	1819-1820	NNP	denotes	C
T19381	1820-1821	-RRB-	denotes	)
T19382	1822-1830	NNP	denotes	Granzyme
T19383	1831-1832	NNP	denotes	B
T19384	1833-1836	CC	denotes	and
T19385	1837-1842	NNP	denotes	IFN-γ
T19386	1843-1853	NN	denotes	expression
T19387	1854-1856	IN	denotes	by
T19388	1857-1862	NNP	denotes	Tbx21
T19389	1862-1863	NNP	denotes	+
T19390	1863-1864	VBD	denotes	/
T19391	1864-1865	CD	denotes	+
T19392	1866-1869	CC	denotes	and
T19393	1870-1875	CD	denotes	Tbx21
T19394	1875-1876	CD	denotes	−
T19395	1876-1877	NN	denotes	/
T19396	1877-1878	CD	denotes	−
T19397	1879-1880	NNP	denotes	T
T19398	1881-1886	NNS	denotes	cells
T19399	1887-1895	VBD	denotes	analyzed
T19400	1896-1898	IN	denotes	in
T19401	1899-1911	JJ	denotes	restimulated
T19402	1912-1917	NNS	denotes	cells
T19403	1918-1922	WDT	denotes	that
T19404	1923-1926	VBD	denotes	had
T19405	1927-1931	VBN	denotes	been
T19406	1932-1940	VBN	denotes	cultured
T19407	1941-1944	IN	denotes	for
T19408	1945-1946	CD	denotes	5
T19409	1947-1949	NN	denotes	d.
T19410	1950-1951	-LRB-	denotes	(
T19411	1951-1952	NNP	denotes	D
T19412	1952-1953	-RRB-	denotes	)
T19413	1954-1959	JJ	denotes	IFN-γ
T19414	1960-1970	NN	denotes	production
T19415	1971-1973	IN	denotes	by
T19416	1974-1979	NNS	denotes	cells
T19417	1980-1990	VBN	denotes	transduced
T19418	1991-1995	IN	denotes	with
T19419	1996-2003	NN	denotes	Eo-VP16
T19420	2004-2006	CC	denotes	or
T19421	2007-2014	NN	denotes	control
T19422	2015-2016	-LRB-	denotes	(
T19423	2016-2019	NNP	denotes	GFP
T19424	2019-2020	-RRB-	denotes	)
T19425	2021-2033	NNS	denotes	retroviruses
T19426	2034-2035	-LRB-	denotes	(
T19427	2035-2037	NN	denotes	RV
T19428	2037-2038	-RRB-	denotes	)
T19429	2039-2047	VBN	denotes	measured
T19430	2048-2050	IN	denotes	on
T19431	2051-2054	NN	denotes	day
T19432	2055-2056	CD	denotes	4
T19433	2057-2062	IN	denotes	after
T19434	2063-2064	CD	denotes	6
T19435	2065-2066	NN	denotes	h
T19436	2067-2069	IN	denotes	of
T19437	2070-2083	NN	denotes	restimulation
T19438	2084-2088	IN	denotes	with
T19439	2089-2092	NNP	denotes	PMA
T19440	2093-2096	CC	denotes	and
T19441	2097-2106	NN	denotes	ionomycin
T19442	2106-2107	.	denotes	.
T19443	2108-2115	NNS	denotes	Numbers
T19444	2116-2120	VBP	denotes	show
T19445	2121-2124	DT	denotes	the
T19446	2125-2135	NN	denotes	percentage
T19447	2136-2138	IN	denotes	of
T19448	2139-2142	NNP	denotes	GFP
T19449	2142-2143	VBP	denotes	+
T19450	2144-2149	JJ	denotes	IFN-γ
T19451	2149-2150	NN	denotes	+
T19452	2151-2156	NNS	denotes	cells
T19453	2156-2157	.	denotes	.
T19454	2158-2165	NNS	denotes	Results
T19455	2166-2169	VBP	denotes	are
T19456	2170-2184	NN	denotes	representative
T19457	2185-2187	IN	denotes	of
T19458	2188-2193	CD	denotes	three
T19459	2194-2195	-LRB-	denotes	(
T19460	2195-2196	DT	denotes	A
T19461	2197-2200	CC	denotes	and
T19462	2201-2202	NNP	denotes	C
T19463	2202-2203	-RRB-	denotes	)
T19464	2204-2206	CC	denotes	or
T19465	2207-2210	CD	denotes	two
T19466	2211-2212	-LRB-	denotes	(
T19467	2212-2213	NN	denotes	B
T19468	2214-2217	CC	denotes	and
T19469	2218-2219	NNP	denotes	D
T19470	2219-2220	-RRB-	denotes	)
T19471	2221-2232	JJ	denotes	independent
T19472	2233-2244	NNS	denotes	experiments
T19473	2244-2245	.	denotes	.
R4804	T6120	T6125	nsubj	Perforin,are
R4805	T6121	T6120	cc	and,Perforin
R4806	T6122	T6123	compound	granzyme,B
R4807	T6123	T6124	compound	B,expression
R4808	T6124	T6120	conj	expression,Perforin
R4809	T6125	T6128	auxpass	are,regulated
R4810	T6126	T6128	neg	not,regulated
R4811	T6127	T6128	advmod	appreciably,regulated
R4812	T6128	T6143	advcl	regulated,compared
R4813	T6129	T6128	agent	by,regulated
R4814	T6130	T6129	pobj	T-bet,by
R4815	T6131	T6132	aux	To,test
R4816	T6132	T6128	xcomp	test,regulated
R4817	T6133	T6134	det	the,model
R4818	T6134	T6132	dobj	model,test
R4819	T6135	T6134	acl	outlined,model
R4820	T6136	T6135	prep	in,outlined
R4821	T6137	T6139	det	the,paragraph
R4822	T6138	T6139	amod	previous,paragraph
R4823	T6139	T6136	pobj	paragraph,in
R4824	T6140	T6135	advmod	directly,outlined
R4825	T6141	T6143	punct	",",compared
R4826	T6142	T6143	nsubj	we,compared
R4827	T6143	T6143	ROOT	compared,compared
R4828	T6144	T6145	det	the,expression
R4829	T6145	T6143	dobj	expression,compared
R4830	T6146	T6145	prep	of,expression
R4831	T6147	T6146	pobj	IFN-γ,of
R4832	T6148	T6147	punct	",",IFN-γ
R4833	T6149	T6168	nmod	perforin,mice
R4834	T6150	T6149	punct	",",perforin
R4835	T6151	T6149	cc	and,perforin
R4836	T6152	T6153	compound	granzyme,B
R4837	T6153	T6149	conj	B,perforin
R4838	T6154	T6153	prep	in,B
R4839	T6155	T6158	nummod	CD8,cells
R4840	T6156	T6158	nummod	+,cells
R4841	T6157	T6158	compound	T,cells
R4842	T6158	T6154	pobj	cells,in
R4843	T6159	T6153	prep	from,B
R4844	T6160	T6159	pobj	WT,from
R4845	T6161	T6160	cc	and,WT
R4846	T6162	T6160	conj	Tbx21,WT
R4847	T6163	T6164	punct	(,T-bet
R4848	T6164	T6162	appos	T-bet,Tbx21
R4849	T6165	T6164	punct	),T-bet
R4850	T6166	T6167	punct	-,deficient
R4851	T6167	T6168	amod	deficient,mice
R4852	T6168	T6147	appos	mice,IFN-γ
R4853	T6169	T6143	punct	.,compared
R4854	T6170	T6171	mark	As,expected
R4855	T6171	T6187	advcl	expected,produced
R4856	T6172	T6175	punct	(,21
R4857	T6173	T6175	nummod	17,21
R4858	T6174	T6175	punct	",",21
R4859	T6175	T6171	parataxis	21,expected
R4860	T6176	T6175	punct	),21
R4861	T6177	T6187	punct	",",produced
R4862	T6178	T6186	amod	naive,cells
R4863	T6179	T6186	nmod	Tbx21,cells
R4864	T6180	T6186	nmod	−,cells
R4865	T6181	T6186	nmod	/,cells
R4866	T6182	T6186	nmod	−,cells
R4867	T6183	T6186	nmod	CD8,cells
R4868	T6184	T6186	nmod	+,cells
R4869	T6185	T6186	compound	T,cells
R4870	T6186	T6187	nsubj	cells,produced
R4871	T6187	T6187	ROOT	produced,produced
R4872	T6188	T6187	dobj	IFN-γ,produced
R4873	T6189	T6190	advmod	poorly,upon
R4874	T6190	T6187	prep	upon,produced
R4875	T6191	T6190	pobj	activation,upon
R4876	T6192	T6193	punct	(,Fig.
R4877	T6193	T6187	dep	Fig.,produced
R4878	T6194	T6195	nummod	2,A
R4879	T6195	T6193	dobj	A,Fig.
R4880	T6196	T6195	punct	),A
R4881	T6197	T6187	punct	.,produced
R4882	T6198	T6208	advmod	Notably,observed
R4883	T6199	T6208	punct	",",observed
R4884	T6200	T6202	det	this,effect
R4885	T6201	T6202	amod	deleterious,effect
R4886	T6202	T6208	nsubjpass	effect,observed
R4887	T6203	T6202	prep	of,effect
R4888	T6204	T6205	compound	T-bet,deficiency
R4889	T6205	T6203	pobj	deficiency,of
R4890	T6206	T6208	auxpass	was,observed
R4891	T6207	T6208	advmod	only,observed
R4892	T6208	T6208	ROOT	observed,observed
R4893	T6209	T6208	prep	in,observed
R4894	T6210	T6209	pcomp	differentiating,in
R4895	T6211	T6214	compound	CD8,cells
R4896	T6212	T6214	nummod	+,cells
R4897	T6213	T6214	compound	T,cells
R4898	T6214	T6210	dobj	cells,differentiating
R4899	T6215	T6210	prep	until,differentiating
R4900	T6216	T6215	pobj	day,until
R4901	T6217	T6216	nummod	4,day
R4902	T6218	T6216	prep	of,day
R4903	T6219	T6218	pobj	culture,of
R4904	T6220	T6208	cc	but,observed
R4905	T6221	T6224	auxpass	was,mitigated
R4906	T6222	T6223	advmod	almost,completely
R4907	T6223	T6224	advmod	completely,mitigated
R4908	T6224	T6208	conj	mitigated,observed
R4909	T6225	T6224	prep	by,mitigated
R4910	T6226	T6225	pobj	day,by
R4911	T6227	T6226	nummod	6,day
R4912	T6228	T6229	punct	(,Fig.
R4913	T6229	T6231	nmod	Fig.,A
R4914	T6230	T6231	nummod	2,A
R4915	T6231	T6224	npadvmod	A,mitigated
R4916	T6232	T6224	punct	),mitigated
R4917	T6233	T6208	punct	.,observed
R4918	T6234	T6237	nsubj	This,reflected
R4919	T6235	T6236	advmod	most,likely
R4920	T6236	T6237	advmod	likely,reflected
R4921	T6237	T6237	ROOT	reflected,reflected
R4922	T6238	T6237	dobj	compensation,reflected
R4923	T6239	T6237	prep	by,reflected
R4924	T6240	T6239	pobj	Eomes,by
R4925	T6241	T6240	punct	",",Eomes
R4926	T6242	T6243	nsubj	which,was
R4927	T6243	T6245	auxpass	was,induced
R4928	T6244	T6245	advmod	strongly,induced
R4929	T6245	T6237	conj	induced,reflected
R4930	T6246	T6245	prep	between,induced
R4931	T6247	T6246	pobj	days,between
R4932	T6248	T6247	nummod	4,days
R4933	T6249	T6247	cc	and,days
R4934	T6250	T6247	conj	6,days
R4935	T6251	T6252	punct	(,Fig.
R4936	T6252	T6247	conj	Fig.,days
R4937	T6253	T6252	nummod	1,Fig.
R4938	T6254	T6252	punct	),Fig.
R4939	T6255	T6237	punct	.,reflected
R4940	T6256	T6263	prep	In,cultured
R4941	T6257	T6256	pobj	contrast,In
R4942	T6258	T6263	punct	",",cultured
R4943	T6259	T6263	dep	T-bet,cultured
R4944	T6260	T6262	amod	deficient,cells
R4945	T6261	T6262	compound	T,cells
R4946	T6262	T6263	nsubj	cells,cultured
R4947	T6263	T6263	ROOT	cultured,cultured
R4948	T6264	T6263	prep	for,cultured
R4949	T6265	T6266	nummod	6,d
R4950	T6266	T6264	pobj	d,for
R4951	T6267	T6263	conj	showed,cultured
R4952	T6268	T6269	det	no,defect
R4953	T6269	T6267	dobj	defect,showed
R4954	T6270	T6269	prep	in,defect
R4955	T6271	T6273	amod	perforin,expression
R4956	T6272	T6273	compound	mRNA,expression
R4957	T6273	T6270	pobj	expression,in
R4958	T6274	T6277	punct	(,B
R4959	T6275	T6277	amod	Fig.,B
R4960	T6276	T6277	nummod	2,B
R4961	T6277	T6273	appos	B,expression
R4962	T6278	T6267	punct	",",showed
R4963	T6279	T6263	conj	compare,cultured
R4964	T6280	T6279	dobj	lanes,compare
R4965	T6281	T6280	nummod	1,lanes
R4966	T6282	T6280	cc	and,lanes
R4967	T6283	T6280	conj	4,lanes
R4968	T6284	T6279	punct	),compare
R4969	T6285	T6263	punct	.,cultured
R4970	T6286	T6288	nsubj	We,observed
R4971	T6287	T6288	advmod	consistently,observed
R4972	T6288	T6288	ROOT	observed,observed
R4973	T6289	T6291	det	a,reduction
R4974	T6290	T6291	amod	modest,reduction
R4975	T6291	T6288	dobj	reduction,observed
R4976	T6292	T6291	prep	in,reduction
R4977	T6293	T6294	compound	GzmB,mRNA
R4978	T6294	T6292	pobj	mRNA,in
R4979	T6295	T6294	prep	in,mRNA
R4980	T6296	T6295	pobj	T-bet,in
R4981	T6297	T6299	amod	deficient,cells
R4982	T6298	T6299	compound	T,cells
R4983	T6299	T6305	nsubj	cells,compare
R4984	T6300	T6299	punct	(,cells
R4985	T6301	T6303	nmod	Fig.,B
R4986	T6302	T6303	nummod	2,B
R4987	T6303	T6299	appos	B,cells
R4988	T6304	T6299	punct	",",cells
R4989	T6305	T6288	ccomp	compare,observed
R4990	T6306	T6305	dobj	lanes,compare
R4991	T6307	T6306	nummod	1,lanes
R4992	T6308	T6306	cc	and,lanes
R4993	T6309	T6306	conj	4,lanes
R4994	T6310	T6309	punct	),4
R4995	T6311	T6306	punct	",",lanes
R4996	T6312	T6315	nsubj	which,translate
R4997	T6313	T6315	aux	did,translate
R4998	T6314	T6315	neg	not,translate
R4999	T6315	T6306	relcl	translate,lanes
R5000	T6316	T6315	prep	into,translate
R5001	T6317	T6318	det	a,decrease
R5002	T6318	T6316	pobj	decrease,into
R5003	T6319	T6318	prep	in,decrease
R5004	T6320	T6319	pobj	expression,in
R5005	T6321	T6320	prep	of,expression
R5006	T6322	T6324	compound	granzyme,protein
R5007	T6323	T6324	compound	B,protein
R5008	T6324	T6321	pobj	protein,of
R5009	T6325	T6326	punct	(,Fig.
R5010	T6326	T6328	nmod	Fig.,C
R5011	T6327	T6328	nummod	2,C
R5012	T6328	T6315	dobj	C,translate
R5013	T6329	T6305	punct	),compare
R5014	T6330	T6288	punct	.,observed
R5015	T6331	T6332	aux	To,examine
R5016	T6332	T6339	advcl	examine,transduced
R5017	T6333	T6334	det	the,role
R5018	T6334	T6332	dobj	role,examine
R5019	T6335	T6334	prep	of,role
R5020	T6336	T6335	pobj	Eomes,of
R5021	T6337	T6339	punct	",",transduced
R5022	T6338	T6339	nsubj	we,transduced
R5023	T6339	T6339	ROOT	transduced,transduced
R5024	T6340	T6344	amod	naive,cells
R5025	T6341	T6344	nmod	CD8,cells
R5026	T6342	T6344	nummod	+,cells
R5027	T6343	T6344	compound	T,cells
R5028	T6344	T6339	dobj	cells,transduced
R5029	T6345	T6344	prep	from,cells
R5030	T6346	T6345	pobj	WT,from
R5031	T6347	T6346	cc	and,WT
R5032	T6348	T6349	compound	Tbx21,−
R5033	T6349	T6346	conj	−,WT
R5034	T6350	T6339	conj	/,transduced
R5035	T6351	T6352	nummod	−,mice
R5036	T6352	T6350	dobj	mice,/
R5037	T6353	T6350	prep	with,/
R5038	T6354	T6353	pobj	retroviruses,with
R5039	T6355	T6354	acl	containing,retroviruses
R5040	T6356	T6359	amod	internal,site
R5041	T6357	T6359	amod	ribosome,site
R5042	T6358	T6359	compound	entry,site
R5043	T6359	T6355	dobj	site,containing
R5044	T6360	T6359	punct	(,site
R5045	T6361	T6359	appos	IRES,site
R5046	T6362	T6359	punct	),site
R5047	T6363	T6363	ROOT	GFP,GFP
R5048	T6364	T6365	nsubj	that,were
R5049	T6365	T6363	relcl	were,GFP
R5050	T6366	T6367	preconj	either,empty
R5051	T6367	T6365	acomp	empty,were
R5052	T6368	T6367	cc	or,empty
R5053	T6369	T6367	conj	encoded,empty
R5054	T6370	T6373	det	a,version
R5055	T6371	T6372	advmod	strongly,transactivating
R5056	T6372	T6373	amod	transactivating,version
R5057	T6373	T6369	dobj	version,encoded
R5058	T6374	T6373	prep	of,version
R5059	T6375	T6374	pobj	Eomes,of
R5060	T6376	T6375	punct	(,Eomes
R5061	T6377	T6375	appos	Eo-VP16,Eomes
R5062	T6378	T6375	punct	),Eomes
R5063	T6379	T6375	punct	(,Eomes
R5064	T6380	T6375	appos	8,Eomes
R5065	T6381	T6375	punct	),Eomes
R5066	T6382	T6369	punct	",",encoded
R5067	T6383	T6369	cc	and,encoded
R5068	T6384	T6369	conj	expanded,encoded
R5069	T6385	T6384	dobj	them,expanded
R5070	T6386	T6384	prep	for,expanded
R5071	T6387	T6386	pobj	6,for
R5072	T6388	T6384	advcl	d,expanded
R5073	T6389	T6388	prep	under,d
R5074	T6390	T6392	poss	our,conditions
R5075	T6391	T6392	compound	culture,conditions
R5076	T6392	T6389	pobj	conditions,under
R5077	T6393	T6339	punct	.,transduced
R5078	T6394	T6403	nsubj	Eo-VP16,increased
R5079	T6395	T6394	punct	",",Eo-VP16
R5080	T6396	T6394	cc	but,Eo-VP16
R5081	T6397	T6401	neg	not,retrovirus
R5082	T6398	T6401	det	the,retrovirus
R5083	T6399	T6401	amod	empty,retrovirus
R5084	T6400	T6401	compound	GFP,retrovirus
R5085	T6401	T6394	conj	retrovirus,Eo-VP16
R5086	T6402	T6401	punct	",",retrovirus
R5087	T6403	T6403	ROOT	increased,increased
R5088	T6404	T6405	compound	perforin,expression
R5089	T6405	T6403	dobj	expression,increased
R5090	T6406	T6403	prep	in,increased
R5091	T6407	T6408	preconj	both,WT
R5092	T6408	T6406	pobj	WT,in
R5093	T6409	T6408	cc	and,WT
R5094	T6410	T6408	conj	T-bet,WT
R5095	T6411	T6415	amod	deficient,cells
R5096	T6412	T6415	nmod	CD8,cells
R5097	T6413	T6415	nummod	+,cells
R5098	T6414	T6415	compound	T,cells
R5099	T6415	T6403	advcl	cells,increased
R5100	T6416	T6415	punct	(,cells
R5101	T6417	T6419	nmod	Fig.,B
R5102	T6418	T6419	nummod	2,B
R5103	T6419	T6415	appos	B,cells
R5104	T6420	T6415	punct	",",cells
R5105	T6421	T6415	conj	lanes,cells
R5106	T6422	T6415	appos	2,cells
R5107	T6423	T6422	punct	",",2
R5108	T6424	T6422	conj	3,2
R5109	T6425	T6424	punct	",",3
R5110	T6426	T6424	conj	5,3
R5111	T6427	T6415	punct	",",cells
R5112	T6428	T6415	cc	and,cells
R5113	T6429	T6415	conj	6,cells
R5114	T6430	T6429	punct	),6
R5115	T6431	T6403	punct	.,increased
R5116	T6432	T6433	mark	As,expected
R5117	T6433	T6437	advcl	expected,rescued
R5118	T6434	T6437	punct	",",rescued
R5119	T6435	T6437	nsubj	Eo-VP16,rescued
R5120	T6436	T6437	advmod	also,rescued
R5121	T6437	T6437	ROOT	rescued,rescued
R5122	T6438	T6440	det	the,defect
R5123	T6439	T6440	amod	early,defect
R5124	T6440	T6437	dobj	defect,rescued
R5125	T6441	T6440	prep	in,defect
R5126	T6442	T6443	amod	IFN-γ,production
R5127	T6443	T6441	pobj	production,in
R5128	T6444	T6437	conj	observed,rescued
R5129	T6445	T6444	prep	in,observed
R5130	T6446	T6445	pobj	T-bet,in
R5131	T6447	T6451	amod	deficient,cells
R5132	T6448	T6451	nmod	CD8,cells
R5133	T6449	T6451	nummod	+,cells
R5134	T6450	T6451	compound	T,cells
R5135	T6451	T6444	dep	cells,observed
R5136	T6452	T6451	punct	(,cells
R5137	T6453	T6455	nmod	Fig.,D
R5138	T6454	T6455	nummod	2,D
R5139	T6455	T6451	appos	D,cells
R5140	T6456	T6451	punct	),cells
R5141	T6457	T6437	punct	.,rescued
R5142	T6458	T6463	advmod	However,induce
R5143	T6459	T6463	punct	",",induce
R5144	T6460	T6463	nsubj	Eo-VP16,induce
R5145	T6461	T6463	aux	did,induce
R5146	T6462	T6463	neg	not,induce
R5147	T6463	T6463	ROOT	induce,induce
R5148	T6464	T6465	compound	GzmB,mRNA
R5149	T6465	T6466	compound	mRNA,expression
R5150	T6466	T6463	dobj	expression,induce
R5151	T6467	T6463	prep	in,induce
R5152	T6468	T6469	preconj	either,WT
R5153	T6469	T6467	pobj	WT,in
R5154	T6470	T6469	cc	or,WT
R5155	T6471	T6469	conj	T-bet,WT
R5156	T6472	T6473	amod	deficient,cells
R5157	T6473	T6463	dobj	cells,induce
R5158	T6474	T6463	punct	;,induce
R5159	T6475	T6463	advmod	thus,induce
R5160	T6476	T6488	punct	",",compensated
R5161	T6477	T6480	det	the,dependence
R5162	T6478	T6480	amod	partial,dependence
R5163	T6479	T6480	compound	T-bet,dependence
R5164	T6480	T6488	nsubjpass	dependence,compensated
R5165	T6481	T6480	prep	of,dependence
R5166	T6482	T6483	compound	GzmB,mRNA
R5167	T6483	T6484	compound	mRNA,expression
R5168	T6484	T6481	pobj	expression,of
R5169	T6485	T6488	aux	can,compensated
R5170	T6486	T6488	neg	not,compensated
R5171	T6487	T6488	auxpass	be,compensated
R5172	T6488	T6488	ROOT	compensated,compensated
R5173	T6489	T6488	prep	for,compensated
R5174	T6490	T6488	agent	by,compensated
R5175	T6491	T6490	pobj	Eo-VP16,by
R5176	T6492	T6488	punct	.,compensated
R14860	T19207	T19207	ROOT	Regulation,Regulation
R14861	T19208	T19207	prep	of,Regulation
R14862	T19209	T19208	pobj	perforin,of
R14863	T19210	T19207	punct	",",Regulation
R14864	T19211	T19212	compound	granzyme,B
R14865	T19212	T19207	appos	B,Regulation
R14866	T19213	T19207	punct	",",Regulation
R14867	T19214	T19207	cc	and,Regulation
R14868	T19215	T19216	compound	IFN-γ,expression
R14869	T19216	T19207	conj	expression,Regulation
R14870	T19217	T19207	prep	by,Regulation
R14871	T19218	T19217	pobj	T-bet,by
R14872	T19219	T19218	cc	and,T-bet
R14873	T19220	T19218	conj	Eomes,T-bet
R14874	T19221	T19207	prep	in,Regulation
R14875	T19222	T19221	pcomp	differentiating,in
R14876	T19223	T19222	dobj	CTLs,differentiating
R14877	T19224	T19207	punct	.,Regulation
R14878	T19225	T19226	punct	(,A
R14879	T19226	T19229	nmod	A,expression
R14880	T19227	T19226	punct	),A
R14881	T19228	T19229	amod	IFN-γ,expression
R14882	T19229	T19229	ROOT	expression,expression
R14883	T19230	T19229	prep	by,expression
R14884	T19231	T19230	pobj	WT,by
R14885	T19232	T19236	punct	(,+
R14886	T19233	T19236	nmod	Tbx21,+
R14887	T19234	T19235	compound	+,/
R14888	T19235	T19233	nummod	/,Tbx21
R14889	T19236	T19231	appos	+,WT
R14890	T19237	T19236	punct	),+
R14891	T19238	T19231	cc	and,WT
R14892	T19239	T19231	conj	T-bet,WT
R14893	T19240	T19229	appos	deficient,expression
R14894	T19241	T19240	punct	(,deficient
R14895	T19242	T19243	nummod	Tbx21,−
R14896	T19243	T19245	nummod	−,−
R14897	T19244	T19245	compound	/,−
R14898	T19245	T19240	appos	−,deficient
R14899	T19246	T19240	punct	),deficient
R14900	T19247	T19248	compound	T,cells
R14901	T19248	T19229	appos	cells,expression
R14902	T19249	T19229	punct	.,expression
R14903	T19250	T19254	amod	Naive,cells
R14904	T19251	T19254	nmod	CD8,cells
R14905	T19252	T19254	nummod	+,cells
R14906	T19253	T19254	compound	T,cells
R14907	T19254	T19268	nsubjpass	cells,restimulated
R14908	T19255	T19254	punct	",",cells
R14909	T19256	T19254	cc	or,cells
R14910	T19257	T19254	conj	cells,cells
R14911	T19258	T19257	acl	activated,cells
R14912	T19259	T19258	cc	and,activated
R14913	T19260	T19258	conj	cultured,activated
R14914	T19261	T19260	prep	for,cultured
R14915	T19262	T19265	nummod	4,d
R14916	T19263	T19262	cc	or,4
R14917	T19264	T19262	conj	6,4
R14918	T19265	T19261	pobj	d,for
R14919	T19266	T19268	punct	",",restimulated
R14920	T19267	T19268	auxpass	were,restimulated
R14921	T19268	T19268	ROOT	restimulated,restimulated
R14923	T19270	T19269	pobj	PMA,with
R14924	T19271	T19270	cc	and,PMA
R14925	T19272	T19270	conj	ionomycin,PMA
R14926	T19273	T19268	prep	for,restimulated
R14927	T19274	T19275	nummod	6,h
R14928	T19275	T19273	pobj	h,for
R14929	T19276	T19268	punct	",",restimulated
R14930	T19277	T19268	cc	and,restimulated
R14931	T19278	T19279	compound	IFN-γ,expression
R14932	T19279	T19281	nsubjpass	expression,assessed
R14933	T19280	T19281	auxpass	was,assessed
R14934	T19281	T19268	conj	assessed,restimulated
R14935	T19282	T19281	agent	by,assessed
R14936	T19283	T19284	amod	intracellular,staining
R14937	T19284	T19282	pobj	staining,by
R14938	T19285	T19281	punct	.,assessed
R14939	T19286	T19287	nsubj	Numbers,show
R14940	T19287	T19287	ROOT	show,show
R14941	T19288	T19289	det	the,percentage
R14942	T19289	T19287	dobj	percentage,show
R14943	T19290	T19289	prep	of,percentage
R14944	T19291	T19293	amod	IFN-γ,cells
R14945	T19292	T19293	compound	+,cells
R14946	T19293	T19290	pobj	cells,of
R14947	T19294	T19287	punct	.,show
R14948	T19295	T19300	punct	(,analysis
R14949	T19296	T19300	nmod	B,analysis
R14950	T19297	T19296	punct	),B
R14951	T19298	T19299	compound	Northern,blot
R14952	T19299	T19300	compound	blot,analysis
R14953	T19300	T19300	ROOT	analysis,analysis
R14954	T19301	T19300	prep	of,analysis
R14955	T19302	T19301	pobj	Prf1,of
R14956	T19303	T19302	cc	and,Prf1
R14957	T19304	T19305	compound	GzmB,mRNA
R14958	T19305	T19306	compound	mRNA,expression
R14959	T19306	T19300	conj	expression,analysis
R14960	T19307	T19300	prep	in,analysis
R14961	T19308	T19307	pobj	WT,in
R14962	T19309	T19308	cc	or,WT
R14963	T19310	T19308	conj	T-bet,WT
R14964	T19311	T19315	amod	deficient,cells
R14965	T19312	T19315	nmod	CD8,cells
R14966	T19313	T19315	nummod	+,cells
R14967	T19314	T19315	compound	T,cells
R14968	T19315	T19300	appos	cells,analysis
R14969	T19316	T19315	acl	activated,cells
R14970	T19317	T19316	cc	and,activated
R14971	T19318	T19319	preconj	either,left
R14972	T19319	T19316	conj	left,activated
R14973	T19320	T19319	oprd	uninfected,left
R14974	T19321	T19322	punct	(,uninf
R14975	T19322	T19320	dep	uninf,uninfected
R14976	T19323	T19322	punct	),uninf
R14977	T19324	T19322	cc	or,uninf
R14978	T19325	T19322	conj	transduced,uninf
R14979	T19326	T19325	prep	with,transduced
R14980	T19327	T19328	nsubj	retroviruses,expressing
R14981	T19328	T19326	pcomp	expressing,with
R14982	T19329	T19328	dobj	Eomes-VP16,expressing
R14983	T19330	T19331	punct	(,Eo-VP16
R14984	T19331	T19329	appos	Eo-VP16,Eomes-VP16
R14985	T19332	T19331	punct	),Eo-VP16
R14986	T19333	T19329	cc	or,Eomes-VP16
R14987	T19334	T19337	det	an,cassette
R14988	T19335	T19337	amod	empty,cassette
R14989	T19336	T19337	compound	IRES-GFP,cassette
R14990	T19337	T19329	conj	cassette,Eomes-VP16
R14991	T19338	T19339	punct	(,GFP
R14992	T19339	T19337	appos	GFP,cassette
R14993	T19340	T19300	punct	),analysis
R14994	T19341	T19300	punct	.,analysis
R14995	T19342	T19344	amod	Total,RNA
R14996	T19343	T19344	amod	cellular,RNA
R14997	T19344	T19346	nsubjpass	RNA,analyzed
R14998	T19345	T19346	auxpass	was,analyzed
R14999	T19346	T19346	ROOT	analyzed,analyzed
R15000	T19347	T19346	prep	on,analyzed
R15001	T19348	T19347	pobj	day,on
R15002	T19349	T19348	nummod	6,day
R15003	T19350	T19348	prep	of,day
R15004	T19351	T19350	pobj	culture,of
R15005	T19352	T19346	punct	.,analyzed
R15006	T19353	T19354	det	The,frequency
R15007	T19354	T19361	nsubj	frequency,was
R15008	T19355	T19354	prep	of,frequency
R15009	T19356	T19357	amod	transduced,cells
R15010	T19357	T19355	pobj	cells,of
R15011	T19358	T19354	prep	in,frequency
R15012	T19359	T19360	det	the,cultures
R15013	T19360	T19358	pobj	cultures,in
R15014	T19361	T19361	ROOT	was,was
R15015	T19362	T19361	acomp	equivalent,was
R15016	T19363	T19362	prep	for,equivalent
R15017	T19364	T19365	det	both,constructs
R15018	T19365	T19363	pobj	constructs,for
R15019	T19366	T19376	punct	(,depicted
R15020	T19367	T19368	nummod	∼,65
R15021	T19368	T19369	quantmod	65,70
R15022	T19369	T19370	nummod	70,%
R15023	T19370	T19376	nsubj	%,depicted
R15024	T19371	T19373	nmod	GFP,cells
R15025	T19372	T19373	nummod	+,cells
R15026	T19373	T19370	appos	cells,%
R15027	T19374	T19370	punct	;,%
R15028	T19375	T19376	neg	not,depicted
R15029	T19376	T19361	parataxis	depicted,was
R15030	T19377	T19376	punct	),depicted
R15031	T19378	T19361	punct	.,was
R15032	T19379	T19386	punct	(,expression
R15033	T19380	T19386	nmod	C,expression
R15034	T19381	T19380	punct	),C
R15035	T19382	T19383	compound	Granzyme,B
R15036	T19383	T19380	appos	B,C
R15037	T19384	T19383	cc	and,B
R15038	T19385	T19386	compound	IFN-γ,expression
R15039	T19386	T19414	nmod	expression,production
R15040	T19387	T19386	prep	by,expression
R15041	T19388	T19387	pobj	Tbx21,by
R15042	T19389	T19390	compound	+,/
R15043	T19390	T19390	ROOT	/,/
R15044	T19391	T19395	nummod	+,/
R15045	T19392	T19391	cc	and,+
R15046	T19393	T19394	nummod	Tbx21,−
R15047	T19394	T19391	conj	−,+
R15048	T19395	T19390	dobj	/,/
R15049	T19396	T19398	nummod	−,cells
R15050	T19397	T19398	compound	T,cells
R15051	T19398	T19395	appos	cells,/
R15052	T19399	T19398	acl	analyzed,cells
R15053	T19400	T19399	prep	in,analyzed
R15054	T19401	T19402	amod	restimulated,cells
R15055	T19402	T19400	pobj	cells,in
R15056	T19403	T19406	nsubjpass	that,cultured
R15057	T19404	T19406	aux	had,cultured
R15058	T19405	T19406	auxpass	been,cultured
R15059	T19406	T19402	relcl	cultured,cells
R15060	T19407	T19406	prep	for,cultured
R15061	T19408	T19409	nummod	5,d.
R15062	T19409	T19407	pobj	d.,for
R15063	T19410	T19411	punct	(,D
R15064	T19411	T19409	appos	D,d.
R15065	T19412	T19390	punct	),/
R15066	T19413	T19414	amod	IFN-γ,production
R15067	T19414	T19414	ROOT	production,production
R15068	T19415	T19414	prep	by,production
R15069	T19416	T19415	pobj	cells,by
R15070	T19417	T19416	acl	transduced,cells
R15071	T19418	T19417	prep	with,transduced
R15072	T19419	T19418	pobj	Eo-VP16,with
R15073	T19420	T19419	cc	or,Eo-VP16
R15074	T19421	T19419	conj	control,Eo-VP16
R15075	T19422	T19419	punct	(,Eo-VP16
R15076	T19423	T19419	appos	GFP,Eo-VP16
R15077	T19424	T19419	punct	),Eo-VP16
R15078	T19425	T19419	appos	retroviruses,Eo-VP16
R15079	T19426	T19425	punct	(,retroviruses
R15080	T19427	T19425	appos	RV,retroviruses
R15081	T19428	T19425	punct	),retroviruses
R15082	T19429	T19414	acl	measured,production
R15083	T19430	T19429	prep	on,measured
R15084	T19431	T19430	pobj	day,on
R15085	T19432	T19431	nummod	4,day
R15086	T19433	T19431	prep	after,day
R15087	T19434	T19435	nummod	6,h
R15088	T19435	T19433	pobj	h,after
R15089	T19436	T19435	prep	of,h
R15090	T19437	T19436	pobj	restimulation,of
R15091	T19438	T19435	prep	with,h
R15092	T19439	T19438	pobj	PMA,with
R15093	T19440	T19439	cc	and,PMA
R15094	T19441	T19439	conj	ionomycin,PMA
R15095	T19442	T19414	punct	.,production
R15096	T19443	T19444	nsubj	Numbers,show
R15097	T19444	T19444	ROOT	show,show
R15098	T19445	T19446	det	the,percentage
R15099	T19446	T19444	dobj	percentage,show
R15100	T19447	T19446	prep	of,percentage
R15101	T19448	T19447	pobj	GFP,of
R15102	T19449	T19452	amod	+,cells
R15103	T19450	T19452	amod	IFN-γ,cells
R15104	T19451	T19452	compound	+,cells
R15105	T19452	T19446	conj	cells,percentage
R15106	T19453	T19444	punct	.,show
R15107	T19454	T19455	nsubj	Results,are
R15108	T19455	T19455	ROOT	are,are
R15109	T19456	T19455	attr	representative,are
R15110	T19457	T19456	prep	of,representative
R15111	T19458	T19472	nummod	three,experiments
R15112	T19459	T19460	punct	(,A
R15113	T19460	T19458	appos	A,three
R15114	T19461	T19460	cc	and,A
R15115	T19462	T19460	conj	C,A
R15116	T19463	T19462	punct	),C
R15117	T19464	T19465	cc	or,two
R15118	T19465	T19460	conj	two,A
R15119	T19466	T19467	punct	(,B
R15120	T19467	T19472	nmod	B,experiments
R15121	T19468	T19467	cc	and,B
R15122	T19469	T19467	conj	D,B
R15123	T19470	T19467	punct	),B
R15124	T19471	T19472	amod	independent,experiments
R15125	T19472	T19457	pobj	experiments,of
R15126	T19473	T19455	punct	.,are
R14922	T19269	T19268	prep	with,restimulated

GO-BP

Id	Subject	Object	Predicate	Lexical cue
T6108	915-924	http://purl.obolibrary.org/obo/GO_0006412	denotes	translate
T19196	999-1009	http://purl.obolibrary.org/obo/GO_0065007	denotes	Regulation
T19197	1201-1216	http://purl.obolibrary.org/obo/GO_0001775	denotes	cells activated
T19198	1492-1507	http://purl.obolibrary.org/obo/GO_0001775	denotes	cells activated
T19199	1650-1658	http://purl.obolibrary.org/obo/GO_0007349	denotes	cellular

GO-CC

Id	Subject	Object	Predicate	Lexical cue
T6898	209-214	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T6899	301-306	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T6900	454-459	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T6901	679-684	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T6902	860-865	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T6903	2302-2307	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T6904	2663-2668	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T6905	2809-2814	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T6906	2912-2917	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T6907	2372-2380	http://purl.obolibrary.org/obo/GO_0005840	denotes	ribosome
T19748	1171-1176	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T19749	1191-1196	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T19750	1201-1206	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T19751	1393-1398	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T19752	1492-1497	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T19753	1725-1730	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T19754	1796-1801	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T19755	1881-1886	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T19756	1912-1917	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T19757	1974-1979	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T19758	2151-2156	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells
T19759	1331-1344	http://purl.obolibrary.org/obo/GO_0005622	denotes	intracellular

sentences

Id	Subject	Object	Predicate	Lexical cue
T6114	648-781	Sentence	denotes	In contrast, T-bet–deficient T cells cultured for 6 d showed no defect in perforin mRNA expression (Fig. 2 B, compare lanes 1 and 4).
T6115	782-988	Sentence	denotes	We consistently observed a modest reduction in GzmB mRNA in T-bet–deficient T cells (Fig. 2 B, compare lanes 1 and 4), which did not translate into a decrease in expression of granzyme B protein (Fig. 2 C).
T6116	2245-2551	Sentence	denotes	To examine the role of Eomes, we transduced naive CD8+ T cells from WT and Tbx21−/− mice with retroviruses containing internal ribosome entry site (IRES)–GFP that were either empty or encoded a strongly transactivating version of Eomes (Eo-VP16) (8), and expanded them for 6 d under our culture conditions.
T6117	2552-2702	Sentence	denotes	Eo-VP16, but not the empty GFP retrovirus, increased perforin expression in both WT and T-bet–deficient CD8+ T cells (Fig. 2 B, lanes 2, 3, 5, and 6).
T6118	2703-2826	Sentence	denotes	As expected, Eo-VP16 also rescued the early defect in IFN-γ production observed in T-bet–deficient CD8+ T cells (Fig. 2 D).
T6119	2827-3015	Sentence	denotes	However, Eo-VP16 did not induce GzmB mRNA expression in either WT or T-bet–deficient cells; thus, the partial T-bet dependence of GzmB mRNA expression cannot be compensated for by Eo-VP16.
T19200	999-1177	Sentence	denotes	Regulation of perforin, granzyme B, and IFN-γ expression by T-bet and Eomes in differentiating CTLs. (A) IFN-γ expression by WT (Tbx21+/+) and T-bet–deficient (Tbx21−/−) T cells.
T19201	1178-1354	Sentence	denotes	Naive CD8+ T cells, or cells activated and cultured for 4 or 6 d, were restimulated with PMA and ionomycin for 6 h, and IFN-γ expression was assessed by intracellular staining.
T19202	1355-1643	Sentence	denotes	Numbers show the percentage of IFN-γ+ cells. (B) Northern blot analysis of Prf1 and GzmB mRNA expression in WT or T-bet–deficient CD8+ T cells activated and either left uninfected (uninf) or transduced with retroviruses expressing Eomes-VP16 (Eo-VP16) or an empty IRES-GFP cassette (GFP).
T19203	1644-1696	Sentence	denotes	Total cellular RNA was analyzed on day 6 of culture.
T19204	1697-2107	Sentence	denotes	The frequency of transduced cells in the cultures was equivalent for both constructs (∼65–70% GFP+ cells; not depicted). (C) Granzyme B and IFN-γ expression by Tbx21+/+ and Tbx21−/− T cells analyzed in restimulated cells that had been cultured for 5 d. (D) IFN-γ production by cells transduced with Eo-VP16 or control (GFP) retroviruses (RV) measured on day 4 after 6 h of restimulation with PMA and ionomycin.
T19205	2108-2157	Sentence	denotes	Numbers show the percentage of GFP+ IFN-γ+ cells.
T19206	2158-2245	Sentence	denotes	Results are representative of three (A and C) or two (B and D) independent experiments.
T6109	0-73	Sentence	denotes	Perforin and granzyme B expression are not appreciably regulated by T-bet
T6110	74-256	Sentence	denotes	To test the model outlined in the previous paragraph directly, we compared the expression of IFN-γ, perforin, and granzyme B in CD8+ T cells from WT and Tbx21 (T-bet)-deficient mice.
T6111	257-356	Sentence	denotes	As expected (17, 21), naive Tbx21−/− CD8+ T cells produced IFN-γ poorly upon activation (Fig. 2 A).
T6112	357-539	Sentence	denotes	Notably, this deleterious effect of T-bet deficiency was only observed in differentiating CD8+ T cells until day 4 of culture but was almost completely mitigated by day 6 (Fig. 2 A).
T6113	540-647	Sentence	denotes	This most likely reflected compensation by Eomes, which was strongly induced between days 4 and 6 (Fig. 1).
T66	0-73	Sentence	denotes	Perforin and granzyme B expression are not appreciably regulated by T-bet
T67	74-256	Sentence	denotes	To test the model outlined in the previous paragraph directly, we compared the expression of IFN-γ, perforin, and granzyme B in CD8+ T cells from WT and Tbx21 (T-bet)-deficient mice.
T68	257-356	Sentence	denotes	As expected (17, 21), naive Tbx21−/− CD8+ T cells produced IFN-γ poorly upon activation (Fig. 2 A).
T69	357-539	Sentence	denotes	Notably, this deleterious effect of T-bet deficiency was only observed in differentiating CD8+ T cells until day 4 of culture but was almost completely mitigated by day 6 (Fig. 2 A).
T70	540-647	Sentence	denotes	This most likely reflected compensation by Eomes, which was strongly induced between days 4 and 6 (Fig. 1).
T71	648-781	Sentence	denotes	In contrast, T-bet–deficient T cells cultured for 6 d showed no defect in perforin mRNA expression (Fig. 2 B, compare lanes 1 and 4).
T72	782-988	Sentence	denotes	We consistently observed a modest reduction in GzmB mRNA in T-bet–deficient T cells (Fig. 2 B, compare lanes 1 and 4), which did not translate into a decrease in expression of granzyme B protein (Fig. 2 C).
T73	989-998	Sentence	denotes	Figure 2.
T74	999-1177	Sentence	denotes	Regulation of perforin, granzyme B, and IFN-γ expression by T-bet and Eomes in differentiating CTLs. (A) IFN-γ expression by WT (Tbx21+/+) and T-bet–deficient (Tbx21−/−) T cells.
T75	1178-1354	Sentence	denotes	Naive CD8+ T cells, or cells activated and cultured for 4 or 6 d, were restimulated with PMA and ionomycin for 6 h, and IFN-γ expression was assessed by intracellular staining.
T76	1355-1643	Sentence	denotes	Numbers show the percentage of IFN-γ+ cells. (B) Northern blot analysis of Prf1 and GzmB mRNA expression in WT or T-bet–deficient CD8+ T cells activated and either left uninfected (uninf) or transduced with retroviruses expressing Eomes-VP16 (Eo-VP16) or an empty IRES-GFP cassette (GFP).
T77	1644-1696	Sentence	denotes	Total cellular RNA was analyzed on day 6 of culture.
T78	1697-2107	Sentence	denotes	The frequency of transduced cells in the cultures was equivalent for both constructs (∼65–70% GFP+ cells; not depicted). (C) Granzyme B and IFN-γ expression by Tbx21+/+ and Tbx21−/− T cells analyzed in restimulated cells that had been cultured for 5 d. (D) IFN-γ production by cells transduced with Eo-VP16 or control (GFP) retroviruses (RV) measured on day 4 after 6 h of restimulation with PMA and ionomycin.
T79	2108-2157	Sentence	denotes	Numbers show the percentage of GFP+ IFN-γ+ cells.
T80	2158-2551	Sentence	denotes	Results are representative of three (A and C) or two (B and D) independent experiments.To examine the role of Eomes, we transduced naive CD8+ T cells from WT and Tbx21−/− mice with retroviruses containing internal ribosome entry site (IRES)–GFP that were either empty or encoded a strongly transactivating version of Eomes (Eo-VP16) (8), and expanded them for 6 d under our culture conditions.
T81	2552-2702	Sentence	denotes	Eo-VP16, but not the empty GFP retrovirus, increased perforin expression in both WT and T-bet–deficient CD8+ T cells (Fig. 2 B, lanes 2, 3, 5, and 6).
T82	2703-2826	Sentence	denotes	As expected, Eo-VP16 also rescued the early defect in IFN-γ production observed in T-bet–deficient CD8+ T cells (Fig. 2 D).
T83	2827-3015	Sentence	denotes	However, Eo-VP16 did not induce GzmB mRNA expression in either WT or T-bet–deficient cells; thus, the partial T-bet dependence of GzmB mRNA expression cannot be compensated for by Eo-VP16.

events-check-again

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T7247	0-8	Protein	denotes	Perforin
T7248	13-23	Protein	denotes	granzyme B
T7249	24-34	Gene_expression	denotes	expression
T7250	24-34	Gene_expression	denotes	expression
T7251	55-64	Regulation	denotes	regulated	true
T7252	55-64	Regulation	denotes	regulated	true
T7253	68-73	Protein	denotes	T-bet
T7254	153-163	Gene_expression	denotes	expression		true
T7255	153-163	Gene_expression	denotes	expression		true
T7256	153-163	Gene_expression	denotes	expression		true
T7257	167-172	Protein	denotes	IFN-γ
T7258	174-182	Protein	denotes	perforin
T7259	188-198	Protein	denotes	granzyme B
T7260	202-205	Protein	denotes	CD8
T7261	227-232	Protein	denotes	Tbx21
T7262	234-239	Protein	denotes	T-bet
T7263	241-250	Negative_regulation	denotes	deficient
T7264	285-290	Protein	denotes	Tbx21
T7265	294-297	Protein	denotes	CD8
T7266	307-315	Gene_expression	denotes	produced	true
T7267	316-321	Protein	denotes	IFN-γ
T7268	393-398	Protein	denotes	T-bet
T7269	399-409	Negative_regulation	denotes	deficiency
T7270	447-450	Protein	denotes	CD8
T7271	583-588	Protein	denotes	Eomes
T7272	609-616	Positive_regulation	denotes	induced
T7273	661-666	Protein	denotes	T-bet
T7274	667-676	Negative_regulation	denotes	deficient
T7275	712-718	Negative_regulation	denotes	defect	true
T7276	722-730	Protein	denotes	perforin
T7277	731-746	Transcription	denotes	mRNA expression
T7278	816-825	Negative_regulation	denotes	reduction
T7279	829-833	Protein	denotes	GzmB
T7280	842-847	Protein	denotes	T-bet
T7281	848-857	Negative_regulation	denotes	deficient
T7282	932-940	Negative_regulation	denotes	decrease
T7283	944-954	Gene_expression	denotes	expression
T7284	958-968	Protein	denotes	granzyme B
T7285	2268-2273	Protein	denotes	Eomes
T7286	2295-2298	Protein	denotes	CD8
T7287	2320-2325	Protein	denotes	Tbx21
T7288	2399-2402	Protein	denotes	GFP
T7289	2475-2480	Protein	denotes	Eomes
T7290	2482-2489	Protein	denotes	Eo-VP16
T7291	2552-2559	Protein	denotes	Eo-VP16
T7292	2579-2582	Protein	denotes	GFP
T7293	2595-2604	Positive_regulation	denotes	increased
T7294	2605-2613	Protein	denotes	perforin
T7295	2614-2624	Gene_expression	denotes	expression
T7296	2640-2645	Protein	denotes	T-bet
T7297	2646-2655	Negative_regulation	denotes	deficient
T7298	2656-2659	Protein	denotes	CD8
T7299	2716-2723	Protein	denotes	Eo-VP16
T7300	2729-2736	Negative_regulation	denotes	rescued
T7301	2747-2753	Negative_regulation	denotes	defect
T7302	2757-2762	Protein	denotes	IFN-γ
T7303	2763-2773	Gene_expression	denotes	production
T7304	2786-2791	Protein	denotes	T-bet
T7305	2792-2801	Negative_regulation	denotes	deficient
T7306	2802-2805	Protein	denotes	CD8
T7307	2836-2843	Protein	denotes	Eo-VP16
T7308	2852-2858	Positive_regulation	denotes	induce	true
T7309	2859-2863	Protein	denotes	GzmB
T7310	2864-2879	Transcription	denotes	mRNA expression
T7311	2896-2901	Protein	denotes	T-bet
T7312	2902-2911	Negative_regulation	denotes	deficient
T7313	2937-2942	Protein	denotes	T-bet
T7314	2943-2953	Positive_regulation	denotes	dependence
T7315	2957-2961	Protein	denotes	GzmB
T7316	2962-2977	Transcription	denotes	mRNA expression
T7317	3007-3014	Protein	denotes	Eo-VP16
T19976	999-1009	Regulation	denotes	Regulation
T19977	999-1009	Regulation	denotes	Regulation
T19978	999-1009	Regulation	denotes	Regulation
T19979	999-1009	Regulation	denotes	Regulation
T19980	999-1009	Regulation	denotes	Regulation
T19981	999-1009	Regulation	denotes	Regulation
T19982	1013-1021	Protein	denotes	perforin
T19983	1023-1033	Protein	denotes	granzyme B
T19984	1039-1044	Protein	denotes	IFN-γ
T19985	1045-1055	Gene_expression	denotes	expression
T19986	1045-1055	Gene_expression	denotes	expression
T19987	1045-1055	Gene_expression	denotes	expression
T19988	1059-1064	Protein	denotes	T-bet
T19989	1069-1074	Protein	denotes	Eomes
T19990	1104-1109	Protein	denotes	IFN-γ
T19991	1110-1120	Gene_expression	denotes	expression		true
T19992	1128-1133	Protein	denotes	Tbx21
T19993	1142-1147	Protein	denotes	T-bet
T19994	1148-1157	Negative_regulation	denotes	deficient
T19995	1159-1164	Protein	denotes	Tbx21
T19996	1184-1187	Protein	denotes	CD8
T19997	1298-1303	Protein	denotes	IFN-γ
T19998	1304-1314	Gene_expression	denotes	expression		true
T19999	1386-1391	Protein	denotes	IFN-γ
T20000	1430-1434	Protein	denotes	Prf1
T20001	1439-1443	Protein	denotes	GzmB
T20002	1444-1459	Transcription	denotes	mRNA expression		true
T20003	1444-1459	Transcription	denotes	mRNA expression		true
T20004	1469-1474	Protein	denotes	T-bet
T20005	1475-1484	Negative_regulation	denotes	deficient
T20006	1485-1488	Protein	denotes	CD8
T20007	1575-1585	Gene_expression	denotes	expressing
T20008	1586-1596	Protein	denotes	Eomes-VP16
T20009	1598-1605	Protein	denotes	Eo-VP16
T20010	1624-1627	Protein	denotes	GFP
T20011	1822-1832	Protein	denotes	Granzyme B
T20012	1837-1842	Protein	denotes	IFN-γ
T20013	1843-1853	Gene_expression	denotes	expression		true
T20014	1843-1853	Gene_expression	denotes	expression		true
T20015	1857-1862	Protein	denotes	Tbx21
T20016	1870-1875	Protein	denotes	Tbx21
T20017	1954-1959	Protein	denotes	IFN-γ
T20018	1960-1970	Gene_expression	denotes	production		true
T20019	1996-2003	Protein	denotes	Eo-VP16
T20020	2016-2019	Protein	denotes	GFP
T20021	2139-2142	Protein	denotes	GFP
T20022	2144-2149	Protein	denotes	IFN-γ
R5715	T7247	T7249	themeOf	Perforin,expression
R5716	T7248	T7250	themeOf	granzyme B,expression
R5717	T7249	T7251	themeOf	expression,regulated
R5718	T7250	T7252	themeOf	expression,regulated
R5719	T7253	T7252	causeOf	T-bet,regulated
R5720	T7253	T7251	causeOf	T-bet,regulated
R5721	T7257	T7256	themeOf	IFN-γ,expression
R5722	T7258	T7255	themeOf	perforin,expression
R5723	T7259	T7254	themeOf	granzyme B,expression
R5724	T7261	T7263	themeOf	Tbx21,deficient
R5725	T7262	T7261	equivalentTo	T-bet,Tbx21
R5726	T7267	T7266	themeOf	IFN-γ,produced
R5727	T7268	T7269	themeOf	T-bet,deficiency
R5728	T7271	T7272	themeOf	Eomes,induced
R5729	T7273	T7274	themeOf	T-bet,deficient
R5730	T7274	T7275	causeOf	deficient,defect
R5731	T7276	T7277	themeOf	perforin,mRNA expression
R5732	T7277	T7275	themeOf	mRNA expression,defect
R5733	T7279	T7278	themeOf	GzmB,reduction
R5734	T7280	T7281	themeOf	T-bet,deficient
R5735	T7281	T7278	causeOf	deficient,reduction
R5736	T7283	T7282	themeOf	expression,decrease
R5737	T7284	T7283	themeOf	granzyme B,expression
R5738	T7290	T7289	equivalentTo	Eo-VP16,Eomes
R5739	T7291	T7293	causeOf	Eo-VP16,increased
R5740	T7294	T7295	themeOf	perforin,expression
R5741	T7295	T7293	themeOf	expression,increased
R5742	T7296	T7297	themeOf	T-bet,deficient
R5743	T7299	T7300	causeOf	Eo-VP16,rescued
R5744	T7301	T7300	themeOf	defect,rescued
R5745	T7302	T7303	themeOf	IFN-γ,production
R5746	T7303	T7301	themeOf	production,defect
R5747	T7304	T7305	themeOf	T-bet,deficient
R5748	T7305	T7301	causeOf	deficient,defect
R5749	T7307	T7308	causeOf	Eo-VP16,induce
R5750	T7309	T7310	themeOf	GzmB,mRNA expression
R5751	T7310	T7308	themeOf	mRNA expression,induce
R5752	T7311	T7312	themeOf	T-bet,deficient
R5753	T7313	T7314	causeOf	T-bet,dependence
R5754	T7315	T7316	themeOf	GzmB,mRNA expression
R5755	T7316	T7314	themeOf	mRNA expression,dependence
R15474	T19982	T19987	themeOf	perforin,expression
R15475	T19983	T19986	themeOf	granzyme B,expression
R15476	T19984	T19985	themeOf	IFN-γ,expression
R15477	T19985	T19977	themeOf	expression,Regulation
R15478	T19985	T19976	themeOf	expression,Regulation
R15479	T19986	T19981	themeOf	expression,Regulation
R15480	T19986	T19980	themeOf	expression,Regulation
R15481	T19987	T19978	themeOf	expression,Regulation
R15482	T19987	T19979	themeOf	expression,Regulation
R15483	T19988	T19977	causeOf	T-bet,Regulation
R15484	T19988	T19978	causeOf	T-bet,Regulation
R15485	T19988	T19980	causeOf	T-bet,Regulation
R15486	T19989	T19981	causeOf	Eomes,Regulation
R15487	T19989	T19976	causeOf	Eomes,Regulation
R15488	T19989	T19979	causeOf	Eomes,Regulation
R15489	T19990	T19991	themeOf	IFN-γ,expression
R15490	T19993	T19994	themeOf	T-bet,deficient
R15491	T19997	T19998	themeOf	IFN-γ,expression
R15492	T20000	T20003	themeOf	Prf1,mRNA expression
R15493	T20001	T20002	themeOf	GzmB,mRNA expression
R15494	T20004	T20005	themeOf	T-bet,deficient
R15495	T20008	T20007	themeOf	Eomes-VP16,expressing
R15496	T20009	T20008	equivalentTo	Eo-VP16,Eomes-VP16
R15497	T20011	T20013	themeOf	Granzyme B,expression
R15498	T20012	T20014	themeOf	IFN-γ,expression
R15499	T20017	T20018	themeOf	IFN-γ,production

bionlp-st-ge-2016-reference-tees

Id	Subject	Object	Predicate	Lexical cue
T7318	0-8	Protein	denotes	Perforin
T7319	13-23	Protein	denotes	granzyme B
T7320	24-34	Gene_expression	denotes	expression
T7321	24-34	Gene_expression	denotes	expression
T7322	55-64	Regulation	denotes	regulated
T7323	55-64	Regulation	denotes	regulated
T7324	55-64	Regulation	denotes	regulated
T7325	167-172	Protein	denotes	IFN-γ
T7326	174-182	Protein	denotes	perforin
T7327	188-198	Protein	denotes	granzyme B
T7328	202-206	Protein	denotes	CD8+
T7329	220-222	Protein	denotes	WT
T7330	227-232	Protein	denotes	Tbx21
T7331	153-163	Gene_expression	denotes	expression
T7332	153-163	Gene_expression	denotes	expression
T7333	153-163	Gene_expression	denotes	expression
T7334	240-250	Negative_regulation	denotes	-deficient
T7335	240-250	Negative_regulation	denotes	-deficient
T7336	294-297	Protein	denotes	CD8
T7337	316-321	Protein	denotes	IFN-γ
T7338	307-315	Gene_expression	denotes	produced
T7339	447-451	Protein	denotes	CD8+
T7340	722-735	Protein	denotes	perforin mRNA
T7341	736-746	Gene_expression	denotes	expression
T7342	712-718	Negative_regulation	denotes	defect
T7343	829-838	Protein	denotes	GzmB mRNA
T7344	958-976	Protein	denotes	granzyme B protein
T7345	978-981	Protein	denotes	Fig
T7346	816-825	Negative_regulation	denotes	reduction
T7347	944-954	Gene_expression	denotes	expression
T7348	944-954	Gene_expression	denotes	expression
T7349	932-940	Negative_regulation	denotes	decrease
T7350	932-940	Negative_regulation	denotes	decrease
T7351	2268-2273	Protein	denotes	Eomes
T7352	2295-2299	Protein	denotes	CD8+
T7353	2313-2315	Protein	denotes	WT
T7354	2320-2325	Protein	denotes	Tbx21
T7355	2555-2559	Protein	denotes	VP16
T7356	2605-2613	Protein	denotes	perforin
T7357	2656-2659	Protein	denotes	CD8
T7358	2614-2624	Gene_expression	denotes	expression
T7359	2595-2604	Positive_regulation	denotes	increased
T7360	2716-2723	Protein	denotes	Eo-VP16
T7361	2757-2762	Protein	denotes	IFN-γ
T7362	2802-2805	Protein	denotes	CD8
T7363	2763-2773	Gene_expression	denotes	production
T7364	2747-2753	Negative_regulation	denotes	defect
T7365	2836-2843	Protein	denotes	Eo-VP16
T7366	2859-2868	Protein	denotes	GzmB mRNA
T7367	2957-2966	Protein	denotes	GzmB mRNA
T7368	3007-3014	Protein	denotes	Eo-VP16
T7369	2869-2879	Gene_expression	denotes	expression
T7370	2967-2977	Gene_expression	denotes	expression
T7371	2852-2858	Positive_regulation	denotes	induce
T20023	1013-1021	Protein	denotes	perforin
T20024	1023-1033	Protein	denotes	granzyme B
T20025	1039-1044	Protein	denotes	IFN-γ
T20026	1045-1055	Gene_expression	denotes	expression
T20027	1045-1055	Gene_expression	denotes	expression
T20028	999-1009	Regulation	denotes	Regulation
T20029	999-1009	Regulation	denotes	Regulation
T20030	1104-1109	Protein	denotes	IFN-γ
T20031	1124-1126	Protein	denotes	WT
T20032	1128-1133	Protein	denotes	Tbx21
T20033	1110-1120	Gene_expression	denotes	expression
T20034	1110-1120	Gene_expression	denotes	expression
T20035	1110-1120	Gene_expression	denotes	expression
T20036	1184-1188	Protein	denotes	CD8+
T20037	1298-1303	Protein	denotes	IFN-γ
T20038	1304-1314	Gene_expression	denotes	expression
T20039	1386-1391	Protein	denotes	IFN-γ
T20040	1430-1434	Protein	denotes	Prf1
T20041	1439-1448	Protein	denotes	GzmB mRNA
T20042	1485-1488	Protein	denotes	CD8
T20043	1592-1596	Protein	denotes	VP16
T20044	1598-1605	Protein	denotes	Eo-VP16
T20045	1449-1459	Gene_expression	denotes	expression
T20046	1449-1459	Gene_expression	denotes	expression
T20047	1575-1585	Gene_expression	denotes	expressing
T20048	1575-1585	Gene_expression	denotes	expressing
T20049	1822-1832	Protein	denotes	Granzyme B
T20050	1837-1842	Protein	denotes	IFN-γ
T20051	1857-1862	Protein	denotes	Tbx21
T20052	1870-1875	Protein	denotes	Tbx21
T20053	1843-1853	Gene_expression	denotes	expression
T20054	1843-1853	Gene_expression	denotes	expression
T20055	1954-1959	Protein	denotes	IFN-γ
T20056	1996-2003	Protein	denotes	Eo-VP16
T20057	1960-1970	Gene_expression	denotes	production
T20058	2139-2149	Protein	denotes	GFP+ IFN-γ
R5756	T7318	T7320	themeOf	Perforin,expression
R5757	T7318	T7322	themeOf	Perforin,regulated
R5758	T7319	T7321	themeOf	granzyme B,expression
R5759	T7320	T7323	themeOf	expression,regulated
R5760	T7321	T7324	themeOf	expression,regulated
R5761	T7325	T7331	themeOf	IFN-γ,expression
R5762	T7326	T7332	themeOf	perforin,expression
R5763	T7327	T7333	themeOf	granzyme B,expression
R5764	T7329	T7334	themeOf	WT,-deficient
R5765	T7330	T7335	themeOf	Tbx21,-deficient
R5766	T7337	T7338	themeOf	IFN-γ,produced
R5767	T7340	T7341	themeOf	perforin mRNA,expression
R5768	T7341	T7342	themeOf	expression,defect
R5769	T7343	T7346	themeOf	GzmB mRNA,reduction
R5770	T7344	T7347	themeOf	granzyme B protein,expression
R5771	T7345	T7348	themeOf	Fig,expression
R5772	T7347	T7349	themeOf	expression,decrease
R5773	T7348	T7350	themeOf	expression,decrease
R5774	T7355	T7359	causeOf	VP16,increased
R5775	T7356	T7358	themeOf	perforin,expression
R5776	T7358	T7359	themeOf	expression,increased
R5777	T7360	T7364	causeOf	Eo-VP16,defect
R5778	T7361	T7363	themeOf	IFN-γ,production
R5779	T7363	T7364	themeOf	production,defect
R5780	T7365	T7371	causeOf	Eo-VP16,induce
R5781	T7366	T7369	themeOf	GzmB mRNA,expression
R5782	T7367	T7370	themeOf	GzmB mRNA,expression
R5783	T7369	T7371	themeOf	expression,induce
R15500	T20023	T20026	themeOf	perforin,expression
R15501	T20025	T20027	themeOf	IFN-γ,expression
R15502	T20026	T20028	themeOf	expression,Regulation
R15503	T20027	T20029	themeOf	expression,Regulation
R15504	T20030	T20033	themeOf	IFN-γ,expression
R15505	T20031	T20034	themeOf	WT,expression
R15506	T20032	T20035	themeOf	Tbx21,expression
R15507	T20037	T20038	themeOf	IFN-γ,expression
R15508	T20040	T20045	themeOf	Prf1,expression
R15509	T20041	T20046	themeOf	GzmB mRNA,expression
R15510	T20043	T20047	themeOf	VP16,expressing
R15511	T20044	T20048	themeOf	Eo-VP16,expressing
R15512	T20049	T20053	themeOf	Granzyme B,expression
R15513	T20050	T20054	themeOf	IFN-γ,expression
R15514	T20055	T20057	themeOf	IFN-γ,production

bionlp-st-ge-2016-reference

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T6101	2896-2901	Protein	denotes	T-bet
T6102	2902-2911	Negative_regulation	denotes	deficient
T6103	2937-2942	Protein	denotes	T-bet
T6104	2943-2953	Positive_regulation	denotes	dependence
T6105	2957-2961	Protein	denotes	GzmB
T6106	2962-2977	Transcription	denotes	mRNA expression
T6107	3007-3014	Protein	denotes	Eo-VP16
T19171	1304-1314	Gene_expression	denotes	expression		true
T19172	1386-1391	Protein	denotes	IFN-γ
T19173	1430-1434	Protein	denotes	Prf1
T19174	1439-1443	Protein	denotes	GzmB
T19175	1444-1459	Transcription	denotes	mRNA expression		true
T19176	1444-1459	Transcription	denotes	mRNA expression		true
T19177	1469-1474	Protein	denotes	T-bet
T19178	1475-1484	Negative_regulation	denotes	deficient
T19179	1485-1488	Protein	denotes	CD8
T19180	1575-1585	Gene_expression	denotes	expressing
T19181	1586-1596	Protein	denotes	Eomes-VP16
T19182	1598-1605	Protein	denotes	Eo-VP16
T19183	1624-1627	Protein	denotes	GFP
T19184	1822-1832	Protein	denotes	Granzyme B
T19185	1837-1842	Protein	denotes	IFN-γ
T19186	1843-1853	Gene_expression	denotes	expression		true
T19149	999-1009	Regulation	denotes	Regulation
T19150	999-1009	Regulation	denotes	Regulation
T19151	999-1009	Regulation	denotes	Regulation
T19152	999-1009	Regulation	denotes	Regulation
T19153	999-1009	Regulation	denotes	Regulation
T19154	999-1009	Regulation	denotes	Regulation
T19155	1013-1021	Protein	denotes	perforin
T19156	1023-1033	Protein	denotes	granzyme B
T19157	1039-1044	Protein	denotes	IFN-γ
T19158	1045-1055	Gene_expression	denotes	expression
T19159	1045-1055	Gene_expression	denotes	expression
T19160	1045-1055	Gene_expression	denotes	expression
T19161	1059-1064	Protein	denotes	T-bet
T19162	1069-1074	Protein	denotes	Eomes
T19163	1104-1109	Protein	denotes	IFN-γ
T19164	1110-1120	Gene_expression	denotes	expression		true
T19165	1128-1133	Protein	denotes	Tbx21
T19166	1142-1147	Protein	denotes	T-bet
T19167	1148-1157	Negative_regulation	denotes	deficient
T19168	1159-1164	Protein	denotes	Tbx21
T19169	1184-1187	Protein	denotes	CD8
T19170	1298-1303	Protein	denotes	IFN-γ
T19187	1843-1853	Gene_expression	denotes	expression		true
T19188	1857-1862	Protein	denotes	Tbx21
T19189	1870-1875	Protein	denotes	Tbx21
T19190	1954-1959	Protein	denotes	IFN-γ
T19191	1960-1970	Gene_expression	denotes	production		true
T19192	1996-2003	Protein	denotes	Eo-VP16
T19193	2016-2019	Protein	denotes	GFP
T19194	2139-2142	Protein	denotes	GFP
T19195	2144-2149	Protein	denotes	IFN-γ
T6037	0-8	Protein	denotes	Perforin
T6038	13-23	Protein	denotes	granzyme B
T6039	24-34	Gene_expression	denotes	expression
T6040	24-34	Gene_expression	denotes	expression
T6041	55-64	Regulation	denotes	regulated	true
T6042	55-64	Regulation	denotes	regulated	true
T6043	68-73	Protein	denotes	T-bet
T6044	153-163	Gene_expression	denotes	expression		true
T6045	153-163	Gene_expression	denotes	expression		true
T6046	153-163	Gene_expression	denotes	expression		true
T6047	167-172	Protein	denotes	IFN-γ
T6048	174-182	Protein	denotes	perforin
T6049	188-198	Protein	denotes	granzyme B
T6050	202-205	Protein	denotes	CD8
T6051	227-232	Protein	denotes	Tbx21
T6052	234-239	Protein	denotes	T-bet
T6053	241-250	Negative_regulation	denotes	deficient
T6054	285-290	Protein	denotes	Tbx21
T6055	294-297	Protein	denotes	CD8
T6056	307-315	Gene_expression	denotes	produced	true
T6057	316-321	Protein	denotes	IFN-γ
T6058	393-398	Protein	denotes	T-bet
T6059	399-409	Negative_regulation	denotes	deficiency
T6060	447-450	Protein	denotes	CD8
T6061	583-588	Protein	denotes	Eomes
T6062	609-616	Positive_regulation	denotes	induced
T6063	661-666	Protein	denotes	T-bet
T6064	667-676	Negative_regulation	denotes	deficient
T6065	712-718	Negative_regulation	denotes	defect	true
T6066	722-730	Protein	denotes	perforin
T6067	731-746	Transcription	denotes	mRNA expression
T6068	816-825	Negative_regulation	denotes	reduction
T6069	829-833	Protein	denotes	GzmB
T6070	842-847	Protein	denotes	T-bet
T6071	848-857	Negative_regulation	denotes	deficient
T6072	932-940	Negative_regulation	denotes	decrease
T6073	944-954	Gene_expression	denotes	expression
T6074	958-968	Protein	denotes	granzyme B
T6075	2268-2273	Protein	denotes	Eomes
T6076	2295-2298	Protein	denotes	CD8
T6077	2320-2325	Protein	denotes	Tbx21
T6078	2399-2402	Protein	denotes	GFP
T6079	2475-2480	Protein	denotes	Eomes
T6080	2482-2489	Protein	denotes	Eo-VP16
T6081	2552-2559	Protein	denotes	Eo-VP16
T6082	2579-2582	Protein	denotes	GFP
T6083	2595-2604	Positive_regulation	denotes	increased
T6084	2605-2613	Protein	denotes	perforin
T6085	2614-2624	Gene_expression	denotes	expression
T6086	2640-2645	Protein	denotes	T-bet
T6087	2646-2655	Negative_regulation	denotes	deficient
T6088	2656-2659	Protein	denotes	CD8
T6089	2716-2723	Protein	denotes	Eo-VP16
T6090	2729-2736	Negative_regulation	denotes	rescued
T6091	2747-2753	Negative_regulation	denotes	defect
T6092	2757-2762	Protein	denotes	IFN-γ
T6093	2763-2773	Gene_expression	denotes	production
T6094	2786-2791	Protein	denotes	T-bet
T6095	2792-2801	Negative_regulation	denotes	deficient
T6096	2802-2805	Protein	denotes	CD8
T6097	2836-2843	Protein	denotes	Eo-VP16
T6098	2852-2858	Positive_regulation	denotes	induce	true
T6099	2859-2863	Protein	denotes	GzmB
T6100	2864-2879	Transcription	denotes	mRNA expression
R14834	T19155	T19160	themeOf	perforin,expression
R14835	T19156	T19159	themeOf	granzyme B,expression
R14836	T19157	T19158	themeOf	IFN-γ,expression
R14837	T19158	T19150	themeOf	expression,Regulation
R14838	T19158	T19149	themeOf	expression,Regulation
R14839	T19159	T19154	themeOf	expression,Regulation
R14840	T19159	T19153	themeOf	expression,Regulation
R14841	T19160	T19151	themeOf	expression,Regulation
R14842	T19160	T19152	themeOf	expression,Regulation
R14843	T19161	T19150	causeOf	T-bet,Regulation
R14844	T19161	T19151	causeOf	T-bet,Regulation
R14845	T19161	T19153	causeOf	T-bet,Regulation
R14846	T19162	T19154	causeOf	Eomes,Regulation
R14847	T19162	T19149	causeOf	Eomes,Regulation
R14848	T19162	T19152	causeOf	Eomes,Regulation
R14849	T19163	T19164	themeOf	IFN-γ,expression
R14850	T19166	T19167	themeOf	T-bet,deficient
R14851	T19170	T19171	themeOf	IFN-γ,expression
R14852	T19173	T19176	themeOf	Prf1,mRNA expression
R14853	T19174	T19175	themeOf	GzmB,mRNA expression
R14854	T19177	T19178	themeOf	T-bet,deficient
R14855	T19181	T19180	themeOf	Eomes-VP16,expressing
R14856	T19182	T19181	equivalentTo	Eo-VP16,Eomes-VP16
R14857	T19184	T19186	themeOf	Granzyme B,expression
R14858	T19185	T19187	themeOf	IFN-γ,expression
R14859	T19190	T19191	themeOf	IFN-γ,production
R4767	T6043	T6042	causeOf	T-bet,regulated
R4769	T6047	T6046	themeOf	IFN-γ,expression
R4770	T6048	T6045	themeOf	perforin,expression
R4771	T6049	T6044	themeOf	granzyme B,expression
R4772	T6051	T6053	themeOf	Tbx21,deficient
R4774	T6057	T6056	themeOf	IFN-γ,produced
R4775	T6058	T6059	themeOf	T-bet,deficiency
R4776	T6061	T6062	themeOf	Eomes,induced
R4777	T6063	T6064	themeOf	T-bet,deficient
R4778	T6064	T6065	causeOf	deficient,defect
R4779	T6066	T6067	themeOf	perforin,mRNA expression
R4780	T6067	T6065	themeOf	mRNA expression,defect
R4781	T6069	T6068	themeOf	GzmB,reduction
R4783	T6071	T6068	causeOf	deficient,reduction
R4763	T6037	T6039	themeOf	Perforin,expression
R4764	T6038	T6040	themeOf	granzyme B,expression
R4765	T6039	T6041	themeOf	expression,regulated
R4766	T6040	T6042	themeOf	expression,regulated
R4768	T6043	T6041	causeOf	T-bet,regulated
R4773	T6052	T6051	equivalentTo	T-bet,Tbx21
R4782	T6070	T6071	themeOf	T-bet,deficient
R4784	T6073	T6072	themeOf	expression,decrease
R4785	T6074	T6073	themeOf	granzyme B,expression
R4786	T6080	T6079	equivalentTo	Eo-VP16,Eomes
R4787	T6081	T6083	causeOf	Eo-VP16,increased
R4788	T6084	T6085	themeOf	perforin,expression
R4789	T6085	T6083	themeOf	expression,increased
R4790	T6086	T6087	themeOf	T-bet,deficient
R4791	T6089	T6090	causeOf	Eo-VP16,rescued
R4792	T6091	T6090	themeOf	defect,rescued
R4793	T6092	T6093	themeOf	IFN-γ,production
R4794	T6093	T6091	themeOf	production,defect
R4795	T6094	T6095	themeOf	T-bet,deficient
R4796	T6095	T6091	causeOf	deficient,defect
R4797	T6097	T6098	causeOf	Eo-VP16,induce
R4798	T6099	T6100	themeOf	GzmB,mRNA expression
R4799	T6100	T6098	themeOf	mRNA expression,induce
R4800	T6101	T6102	themeOf	T-bet,deficient
R4801	T6103	T6104	causeOf	T-bet,dependence
R4802	T6105	T6106	themeOf	GzmB,mRNA expression
R4803	T6106	T6104	themeOf	mRNA expression,dependence

bionlp-st-ge-2016-uniprot

Id	Subject	Object	Predicate	Lexical cue
T6840	0-8	P14222	denotes	Perforin
T6841	13-23	P10144	denotes	granzyme B
T6842	68-73	Q9UL17	denotes	T-bet
T6843	167-172	P01579	denotes	IFN-γ
T6844	174-182	P14222	denotes	perforin
T6845	188-198	P10144	denotes	granzyme B
T6846	202-205	P10966	denotes	CD8
T6847	202-205	P01732	denotes	CD8
T6848	227-232	Q9UL17	denotes	Tbx21
T6849	234-239	Q9UL17	denotes	T-bet
T6850	285-290	Q9UL17	denotes	Tbx21
T6851	294-297	P10966	denotes	CD8
T6852	294-297	P01732	denotes	CD8
T6853	316-321	P01579	denotes	IFN-γ
T6854	393-398	Q9UL17	denotes	T-bet
T6855	447-450	P10966	denotes	CD8
T6856	447-450	P01732	denotes	CD8
T6857	583-588	O95936	denotes	Eomes
T6858	661-666	Q9UL17	denotes	T-bet
T6859	722-730	P14222	denotes	perforin
T6860	829-833	P10144	denotes	GzmB
T6861	842-847	Q9UL17	denotes	T-bet
T6862	958-968	P10144	denotes	granzyme B
T6863	2268-2273	O95936	denotes	Eomes
T6864	2295-2298	P10966	denotes	CD8
T6865	2295-2298	P01732	denotes	CD8
T6866	2320-2325	Q9UL17	denotes	Tbx21
T6867	2399-2402	Q9U6Y4	denotes	GFP
T6868	2475-2480	O95936	denotes	Eomes
T6869	2482-2489	O95936	denotes	Eo-VP16
T6870	2552-2559	O95936	denotes	Eo-VP16
T6871	2579-2582	Q9U6Y4	denotes	GFP
T6872	2605-2613	P14222	denotes	perforin
T6873	2640-2645	Q9UL17	denotes	T-bet
T6874	2656-2659	P10966	denotes	CD8
T6875	2656-2659	P01732	denotes	CD8
T6876	2716-2723	O95936	denotes	Eo-VP16
T6877	2757-2762	P01579	denotes	IFN-γ
T6878	2786-2791	Q9UL17	denotes	T-bet
T6879	2802-2805	P01732	denotes	CD8
T6880	2802-2805	P10966	denotes	CD8
T6881	2836-2843	O95936	denotes	Eo-VP16
T6882	2859-2863	P10144	denotes	GzmB
T6883	2896-2901	Q9UL17	denotes	T-bet
T6884	2937-2942	Q9UL17	denotes	T-bet
T6885	2957-2961	P10144	denotes	GzmB
T6886	3007-3014	O95936	denotes	Eo-VP16
T19709	1013-1021	P14222	denotes	perforin
T19710	1023-1033	P10144	denotes	granzyme B
T19711	1039-1044	P01579	denotes	IFN-γ
T19712	1059-1064	Q9UL17	denotes	T-bet
T19713	1069-1074	O95936	denotes	Eomes
T19714	1104-1109	P01579	denotes	IFN-γ
T19715	1128-1133	Q9UL17	denotes	Tbx21
T19716	1142-1147	Q9UL17	denotes	T-bet
T19717	1159-1164	Q9UL17	denotes	Tbx21
T19718	1184-1187	P01732	denotes	CD8
T19719	1184-1187	P10966	denotes	CD8
T19720	1298-1303	P01579	denotes	IFN-γ
T19721	1386-1391	P01579	denotes	IFN-γ
T19722	1430-1434	P14222	denotes	Prf1
T19723	1439-1443	P10144	denotes	GzmB
T19724	1469-1474	Q9UL17	denotes	T-bet
T19725	1485-1488	P10966	denotes	CD8
T19726	1485-1488	P01732	denotes	CD8
T19727	1586-1591	O95936	denotes	Eomes
T19728	1598-1605	O95936	denotes	Eo-VP16
T19729	1624-1627	Q9U6Y4	denotes	GFP
T19730	1638-1641	Q9U6Y4	denotes	GFP
T19731	1791-1794	Q9U6Y4	denotes	GFP
T19732	1822-1832	P10144	denotes	Granzyme B
T19733	1837-1842	P01579	denotes	IFN-γ
T19734	1857-1862	Q9UL17	denotes	Tbx21
T19735	1870-1875	Q9UL17	denotes	Tbx21
T19736	1954-1959	P01579	denotes	IFN-γ
T19737	1996-2003	O95936	denotes	Eo-VP16
T19738	2016-2019	Q9U6Y4	denotes	GFP
T19739	2139-2142	Q9U6Y4	denotes	GFP
T19740	2144-2149	P01579	denotes	IFN-γ

test2

Id	Subject	Object	Predicate	Lexical cue	Negation	Speculation
T5971	0-8	Protein	denotes	Perforin
T5972	13-23	Protein	denotes	granzyme B
T5973	24-34	Gene_expression	denotes	expression	true
T5974	55-64	Regulation	denotes	regulated	true
T5975	153-163	Gene_expression	denotes	expression		true
T5976	167-172	Protein	denotes	IFN-γ		true
T5977	174-182	Protein	denotes	perforin		true
T5978	188-198	Protein	denotes	granzyme B
T5979	202-205	Protein	denotes	CD8	true
T5980	227-232	Protein	denotes	Tbx21
T5981	234-239	Protein	denotes	T-bet
T5982	241-250	Negative_regulation	denotes	deficient
T5983	285-290	Protein	denotes	Tbx21	true
T5984	294-297	Protein	denotes	CD8
T5985	307-315	Gene_expression	denotes	produced
T5986	316-321	Protein	denotes	IFN-γ
T5987	393-398	Protein	denotes	T-bet
T5988	399-409	Negative_regulation	denotes	deficiency
T5989	447-450	Protein	denotes	CD8
T5990	509-518	Negative_regulation	denotes	mitigated
T5991	583-588	Protein	denotes	Eomes
T5992	609-616	Positive_regulation	denotes	induced
T5993	661-666	Protein	denotes	T-bet
T5994	667-676	Negative_regulation	denotes	deficient
T5995	712-718	Negative_regulation	denotes	defect
T5996	722-730	Protein	denotes	perforin	true
T5997	731-746	Transcription	denotes	mRNA expression
T5998	816-825	Negative_regulation	denotes	reduction
T5999	829-833	Protein	denotes	GzmB
T6000	842-847	Protein	denotes	T-bet
T6001	848-857	Negative_regulation	denotes	deficient
T6002	932-940	Negative_regulation	denotes	decrease
T6003	944-954	Gene_expression	denotes	expression
T6004	958-968	Protein	denotes	granzyme B
T6005	2268-2273	Protein	denotes	Eomes
T6006	2295-2298	Protein	denotes	CD8
T6007	2320-2325	Protein	denotes	Tbx21
T6008	2399-2402	Protein	denotes	GFP
T6009	2475-2480	Protein	denotes	Eomes
T6010	2482-2489	Protein	denotes	Eo-VP16
T6011	2552-2559	Protein	denotes	Eo-VP16
T6012	2579-2582	Protein	denotes	GFP
T6013	2595-2604	Positive_regulation	denotes	increased
T6014	2605-2613	Protein	denotes	perforin
T6015	2614-2624	Gene_expression	denotes	expression
T6016	2640-2645	Protein	denotes	T-bet
T6017	2646-2655	Negative_regulation	denotes	deficient
T6018	2656-2659	Protein	denotes	CD8
T6019	2716-2723	Protein	denotes	Eo-VP16
T6020	2747-2753	Negative_regulation	denotes	defect
T6021	2757-2762	Protein	denotes	IFN-γ
T6022	2763-2773	Gene_expression	denotes	production
T6023	2786-2791	Protein	denotes	T-bet
T6024	2792-2801	Negative_regulation	denotes	deficient
T6025	2802-2805	Protein	denotes	CD8
T6026	2836-2843	Protein	denotes	Eo-VP16
T6027	2852-2858	Positive_regulation	denotes	induce
T6028	2859-2863	Protein	denotes	GzmB
T6029	2864-2879	Transcription	denotes	mRNA expression
T6030	2896-2901	Protein	denotes	T-bet
T6031	2902-2911	Negative_regulation	denotes	deficient
T6032	2937-2942	Protein	denotes	T-bet
T6033	2943-2953	Positive_regulation	denotes	dependence
T6034	2957-2961	Protein	denotes	GzmB
T6035	2962-2977	Transcription	denotes	mRNA expression
T6036	3007-3014	Protein	denotes	Eo-VP16
T19110	999-1009	Regulation	denotes	Regulation
T19111	1013-1021	Protein	denotes	perforin
T19112	1023-1033	Protein	denotes	granzyme B
T19113	1039-1044	Protein	denotes	IFN-γ
T19114	1045-1055	Gene_expression	denotes	expression
T19115	1059-1064	Protein	denotes	T-bet
T19116	1069-1074	Protein	denotes	Eomes
T19117	1104-1109	Protein	denotes	IFN-γ
T19118	1110-1120	Gene_expression	denotes	expression
T19119	1128-1133	Protein	denotes	Tbx21		true
T19120	1142-1147	Protein	denotes	T-bet
T19121	1148-1157	Negative_regulation	denotes	deficient		true
T19122	1159-1164	Protein	denotes	Tbx21		true
T19123	1184-1187	Protein	denotes	CD8		true
T19124	1298-1303	Protein	denotes	IFN-γ
T19125	1304-1314	Gene_expression	denotes	expression
T19126	1386-1391	Protein	denotes	IFN-γ		true
T19127	1430-1434	Protein	denotes	Prf1		true
T19128	1439-1443	Protein	denotes	GzmB		true
T19129	1444-1459	Transcription	denotes	mRNA expression
T19130	1469-1474	Protein	denotes	T-bet
T19131	1475-1484	Negative_regulation	denotes	deficient
T19132	1485-1488	Protein	denotes	CD8
T19133	1575-1585	Gene_expression	denotes	expressing
T19134	1586-1596	Protein	denotes	Eomes-VP16
T19135	1598-1605	Protein	denotes	Eo-VP16
T19136	1624-1627	Protein	denotes	GFP
T19137	1822-1832	Protein	denotes	Granzyme B
T19138	1837-1842	Protein	denotes	IFN-γ
T19139	1843-1853	Gene_expression	denotes	expression
T19140	1857-1862	Protein	denotes	Tbx21
T19141	1870-1875	Protein	denotes	Tbx21
T19142	1954-1959	Protein	denotes	IFN-γ
T19143	1960-1970	Gene_expression	denotes	production
T19144	1980-1990	Positive_regulation	denotes	transduced
T19145	1996-2003	Protein	denotes	Eo-VP16
T19146	2016-2019	Protein	denotes	GFP
T19147	2139-2142	Protein	denotes	GFP
T19148	2144-2149	Protein	denotes	IFN-γ
R4725	T5971	T5973	themeOf	Perforin,expression
R4726	T5972	T5973	themeOf	granzyme B,expression
R4727	T5973	T5974	themeOf	expression,regulated
R4728	T5976	T5975	themeOf	IFN-γ,expression
R4729	T5977	T5975	themeOf	perforin,expression
R4730	T5978	T5975	themeOf	granzyme B,expression
R4731	T5980	T5982	themeOf	Tbx21,deficient
R4732	T5981	T5980	equivalentTo	T-bet,Tbx21
R4733	T5986	T5985	themeOf	IFN-γ,produced
R4734	T5987	T5988	themeOf	T-bet,deficiency
R4735	T5991	T5992	themeOf	Eomes,induced
R4736	T5993	T5994	themeOf	T-bet,deficient
R4737	T5994	T5995	causeOf	deficient,defect
R4738	T5996	T5997	themeOf	perforin,mRNA expression
R4739	T5997	T5995	themeOf	mRNA expression,defect
R4740	T5999	T5998	themeOf	GzmB,reduction
R4741	T6000	T6001	themeOf	T-bet,deficient
R4742	T6001	T5998	causeOf	deficient,reduction
R4743	T6003	T6002	themeOf	expression,decrease
R4744	T6004	T6003	themeOf	granzyme B,expression
R4745	T6010	T6009	equivalentTo	Eo-VP16,Eomes
R4746	T6011	T6013	causeOf	Eo-VP16,increased
R4747	T6014	T6015	themeOf	perforin,expression
R4748	T6015	T6013	themeOf	expression,increased
R4749	T6016	T6017	themeOf	T-bet,deficient
R4750	T6019	T6020	causeOf	Eo-VP16,defect
R4751	T6021	T6022	themeOf	IFN-γ,production
R4752	T6022	T6020	themeOf	production,defect
R4753	T6023	T6024	themeOf	T-bet,deficient
R4754	T6024	T6020	causeOf	deficient,defect
R4755	T6026	T6027	causeOf	Eo-VP16,induce
R4756	T6028	T6029	themeOf	GzmB,mRNA expression
R4757	T6029	T6027	themeOf	mRNA expression,induce
R4758	T6030	T6031	themeOf	T-bet,deficient
R4759	T6031	T6027	causeOf	deficient,induce
R4760	T6032	T6033	causeOf	T-bet,dependence
R4761	T6034	T6035	themeOf	GzmB,mRNA expression
R4762	T6035	T6033	themeOf	mRNA expression,dependence
R14816	T19111	T19114	themeOf	perforin,expression
R14817	T19112	T19114	themeOf	granzyme B,expression
R14818	T19113	T19114	themeOf	IFN-γ,expression
R14819	T19114	T19110	themeOf	expression,Regulation
R14820	T19115	T19110	causeOf	T-bet,Regulation
R14821	T19116	T19110	causeOf	Eomes,Regulation
R14822	T19117	T19118	themeOf	IFN-γ,expression
R14823	T19120	T19121	themeOf	T-bet,deficient
R14824	T19124	T19125	themeOf	IFN-γ,expression
R14825	T19127	T19129	themeOf	Prf1,mRNA expression
R14826	T19128	T19129	themeOf	GzmB,mRNA expression
R14827	T19130	T19131	themeOf	T-bet,deficient
R14828	T19134	T19133	themeOf	Eomes-VP16,expressing
R14829	T19135	T19134	equivalentTo	Eo-VP16,Eomes-VP16
R14830	T19137	T19139	themeOf	Granzyme B,expression
R14831	T19138	T19139	themeOf	IFN-γ,expression
R14832	T19142	T19143	themeOf	IFN-γ,production
R14833	T19145	T19144	themeOf	Eo-VP16,transduced

PMC:2626671 / 10885-13900 JSONTXT

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PMC:2626671 / 10885-13900 JSON TXT