PMC:2222968 / 813-1129 JSONTXT

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    pmc-enju-pas

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confirmed in Th2 cells and in T cells of transgenic mice overexpressing GATA-3 in T cells, which are shown to be deficient in transforming growth factor (TGF)-β–mediated FOXP3 induction. This inhibition is mediated by direct binding of GATA3 to the FOXP3 promoter, which represses its transactivation process. T"}

    bionlp-st-ge-2016-coref

    {"project":"bionlp-st-ge-2016-coref","denotations":[{"id":"T337","span":{"begin":192,"end":207},"obj":"Anaphor"},{"id":"T338","span":{"begin":118,"end":127},"obj":"Antecedent"}],"relations":[{"id":"R635","pred":"boundBy","subj":"T337","obj":"T338"}],"namespaces":[{"prefix":"_base","uri":"https://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"also confirmed in Th2 cells and in T cells of transgenic mice overexpressing GATA-3 in T cells, which are shown to be deficient in transforming growth factor (TGF)-β–mediated FOXP3 induction. This inhibition is mediated by direct binding of GATA3 to the FOXP3 promoter, which represses its transactivation process. T"}

    bionlp-st-ge-2016-spacy-parsed

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This inhibition is mediated by direct binding of GATA3 to the FOXP3 promoter, which represses its transactivation process. T"}

    GO-BP

    {"project":"GO-BP","denotations":[{"id":"T70","span":{"begin":144,"end":150},"obj":"http://purl.obolibrary.org/obo/GO_0040007"},{"id":"T71","span":{"begin":290,"end":305},"obj":"http://purl.obolibrary.org/obo/GO_2000144"}],"text":"also confirmed in Th2 cells and in T cells of transgenic mice overexpressing GATA-3 in T cells, which are shown to be deficient in transforming growth factor (TGF)-β–mediated FOXP3 induction. This inhibition is mediated by direct binding of GATA3 to the FOXP3 promoter, which represses its transactivation process. T"}

    GO-MF

    {"project":"GO-MF","denotations":[{"id":"T634","span":{"begin":230,"end":237},"obj":"http://purl.obolibrary.org/obo/GO_0005488"}],"text":"also confirmed in Th2 cells and in T cells of transgenic mice overexpressing GATA-3 in T cells, which are shown to be deficient in transforming growth factor (TGF)-β–mediated FOXP3 induction. This inhibition is mediated by direct binding of GATA3 to the FOXP3 promoter, which represses its transactivation process. T"}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T636","span":{"begin":22,"end":27},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T637","span":{"begin":37,"end":42},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T638","span":{"begin":89,"end":94},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"also confirmed in Th2 cells and in T cells of transgenic mice overexpressing GATA-3 in T cells, which are shown to be deficient in transforming growth factor (TGF)-β–mediated FOXP3 induction. This inhibition is mediated by direct binding of GATA3 to the FOXP3 promoter, which represses its transactivation process. T"}

    sentences

    {"project":"sentences","denotations":[{"id":"T64","span":{"begin":192,"end":314},"obj":"Sentence"},{"id":"T8","span":{"begin":192,"end":314},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"also confirmed in Th2 cells and in T cells of transgenic mice overexpressing GATA-3 in T cells, which are shown to be deficient in transforming growth factor (TGF)-β–mediated FOXP3 induction. This inhibition is mediated by direct binding of GATA3 to the FOXP3 promoter, which represses its transactivation process. T"}

    events-check-again

    {"project":"events-check-again","denotations":[{"id":"T768","span":{"begin":131,"end":165},"obj":"Protein"},{"id":"T769","span":{"begin":166,"end":174},"obj":"Positive_regulation"},{"id":"T770","span":{"begin":175,"end":180},"obj":"Protein"},{"id":"T771","span":{"begin":181,"end":190},"obj":"Positive_regulation"},{"id":"T772","span":{"begin":211,"end":219},"obj":"Positive_regulation"},{"id":"T773","span":{"begin":230,"end":237},"obj":"Binding"},{"id":"T774","span":{"begin":241,"end":246},"obj":"Protein"},{"id":"T775","span":{"begin":254,"end":259},"obj":"Protein"},{"id":"T776","span":{"begin":260,"end":268},"obj":"Entity"},{"id":"T765","span":{"begin":62,"end":76},"obj":"Gene_expression"},{"id":"T766","span":{"begin":77,"end":83},"obj":"Protein"},{"id":"T767","span":{"begin":118,"end":127},"obj":"Negative_regulation"}],"relations":[{"id":"R599","pred":"causeOf","subj":"T768","obj":"T769"},{"id":"R600","pred":"themeOf","subj":"T769","obj":"T767"},{"id":"R601","pred":"themeOf","subj":"T770","obj":"T771"},{"id":"R602","pred":"themeOf","subj":"T771","obj":"T769"},{"id":"R603","pred":"causeOf","subj":"T773","obj":"T772"},{"id":"R604","pred":"themeOf","subj":"T774","obj":"T773"},{"id":"R605","pred":"themeOf","subj":"T776","obj":"T773"},{"id":"R606","pred":"partOf","subj":"T776","obj":"T775"},{"id":"R662","pred":"themeOf","subj":"T766","obj":"T765"},{"id":"R663","pred":"themeOf","subj":"T767","obj":"T772"}],"text":"also confirmed in Th2 cells and in T cells of transgenic mice overexpressing GATA-3 in T cells, which are shown to be deficient in transforming growth factor (TGF)-β–mediated FOXP3 induction. This inhibition is mediated by direct binding of GATA3 to the FOXP3 promoter, which represses its transactivation process. T"}

    bionlp-st-ge-2016-reference-tees

    {"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T657","span":{"begin":77,"end":83},"obj":"Protein"},{"id":"T658","span":{"begin":175,"end":180},"obj":"Protein"},{"id":"T659","span":{"begin":62,"end":76},"obj":"Gene_expression"},{"id":"T660","span":{"begin":181,"end":190},"obj":"Positive_regulation"},{"id":"T661","span":{"begin":118,"end":127},"obj":"Negative_regulation"},{"id":"T662","span":{"begin":241,"end":246},"obj":"Protein"},{"id":"T663","span":{"begin":254,"end":268},"obj":"Protein"},{"id":"T664","span":{"begin":230,"end":237},"obj":"Binding"},{"id":"T665","span":{"begin":230,"end":237},"obj":"Binding"}],"relations":[{"id":"R555","pred":"themeOf","subj":"T662","obj":"T665"},{"id":"R556","pred":"themeOf","subj":"T663","obj":"T665"},{"id":"R551","pred":"themeOf","subj":"T657","obj":"T659"},{"id":"R552","pred":"themeOf","subj":"T658","obj":"T660"},{"id":"R553","pred":"themeOf","subj":"T660","obj":"T661"},{"id":"R554","pred":"themeOf","subj":"T662","obj":"T664"}],"text":"also confirmed in Th2 cells and in T cells of transgenic mice overexpressing GATA-3 in T cells, which are shown to be deficient in transforming growth factor (TGF)-β–mediated FOXP3 induction. This inhibition is mediated by direct binding of GATA3 to the FOXP3 promoter, which represses its transactivation process. T"}

    bionlp-st-ge-2016-reference

    {"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T105","span":{"begin":77,"end":83},"obj":"Protein"},{"id":"T106","span":{"begin":131,"end":165},"obj":"Protein"},{"id":"T78","span":{"begin":181,"end":190},"obj":"Positive_regulation"},{"id":"T79","span":{"begin":211,"end":219},"obj":"Positive_regulation"},{"id":"T80","span":{"begin":230,"end":237},"obj":"Binding"},{"id":"T88","span":{"begin":62,"end":76},"obj":"Gene_expression"},{"id":"T89","span":{"begin":118,"end":127},"obj":"Negative_regulation"},{"id":"T90","span":{"begin":166,"end":174},"obj":"Positive_regulation"},{"id":"T92","span":{"begin":175,"end":180},"obj":"Protein"},{"id":"T93","span":{"begin":241,"end":246},"obj":"Protein"},{"id":"T94","span":{"begin":254,"end":259},"obj":"Protein"},{"id":"T100","span":{"begin":260,"end":268},"obj":"Entity"}],"relations":[{"id":"R623","pred":"themeOf","subj":"T89","obj":"T79"},{"id":"R624","pred":"themeOf","subj":"T90","obj":"T89"},{"id":"R625","pred":"themeOf","subj":"T92","obj":"T78"},{"id":"R626","pred":"themeOf","subj":"T93","obj":"T80"},{"id":"R631","pred":"themeOf","subj":"T100","obj":"T80"},{"id":"R632","pred":"partOf","subj":"T100","obj":"T94"},{"id":"R42","pred":"themeOf","subj":"T105","obj":"T88"},{"id":"R43","pred":"causeOf","subj":"T106","obj":"T90"},{"id":"R618","pred":"themeOf","subj":"T78","obj":"T90"},{"id":"R619","pred":"causeOf","subj":"T80","obj":"T79"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"also confirmed in Th2 cells and in T cells of transgenic mice overexpressing GATA-3 in T cells, which are shown to be deficient in transforming growth factor (TGF)-β–mediated FOXP3 induction. This inhibition is mediated by direct binding of GATA3 to the FOXP3 promoter, which represses its transactivation process. T"}

    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T345","span":{"begin":77,"end":83},"obj":"P23771"},{"id":"T346","span":{"begin":175,"end":180},"obj":"Q9BZS1"},{"id":"T347","span":{"begin":241,"end":246},"obj":"P23771"},{"id":"T348","span":{"begin":254,"end":259},"obj":"Q9BZS1"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"also confirmed in Th2 cells and in T cells of transgenic mice overexpressing GATA-3 in T cells, which are shown to be deficient in transforming growth factor (TGF)-β–mediated FOXP3 induction. This inhibition is mediated by direct binding of GATA3 to the FOXP3 promoter, which represses its transactivation process. T"}

    test2

    {"project":"test2","denotations":[{"id":"T42","span":{"begin":62,"end":76},"obj":"Gene_expression"},{"id":"T43","span":{"begin":77,"end":83},"obj":"Protein"},{"id":"T44","span":{"begin":118,"end":127},"obj":"Negative_regulation"},{"id":"T45","span":{"begin":131,"end":165},"obj":"Protein"},{"id":"T46","span":{"begin":166,"end":174},"obj":"Positive_regulation"},{"id":"T47","span":{"begin":175,"end":180},"obj":"Protein"},{"id":"T48","span":{"begin":181,"end":190},"obj":"Positive_regulation"},{"id":"T49","span":{"begin":230,"end":237},"obj":"Binding"},{"id":"T50","span":{"begin":241,"end":246},"obj":"Protein"},{"id":"T51","span":{"begin":254,"end":259},"obj":"Protein"},{"id":"T52","span":{"begin":260,"end":268},"obj":"Entity"}],"relations":[{"id":"R30","pred":"themeOf","subj":"T43","obj":"T42"},{"id":"R31","pred":"themeOf","subj":"T47","obj":"T48"},{"id":"R32","pred":"themeOf","subj":"T48","obj":"T46"},{"id":"R33","pred":"themeOf","subj":"T50","obj":"T49"},{"id":"R34","pred":"partOf","subj":"T52","obj":"T51"},{"id":"R35","pred":"themeOf","subj":"T52","obj":"T49"}],"text":"also confirmed in Th2 cells and in T cells of transgenic mice overexpressing GATA-3 in T cells, which are shown to be deficient in transforming growth factor (TGF)-β–mediated FOXP3 induction. This inhibition is mediated by direct binding of GATA3 to the FOXP3 promoter, which represses its transactivation process. T"}