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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/2222968","sourcedb":"PMC","sourceid":"2222968","source_url":"http://www.ncbi.nlm.nih.gov/pmc/2222968","text":"ed diseases.\n\nIt is shown that Th2 responses prevent the generation of inducible Tregs. This is mediated by IL-4 induction of GATA3, which binds directly to and represses the FOXP3 promoter. This mechanism is likely to be relevant in the induction of immunotolerance, particularly in allergic diseases.\n\nIntroduc","divisions":[{"label":"Abstract","span":{"begin":14,"end":303}}],"tracks":[{"project":"sentences","denotations":[{"id":"T18","span":{"begin":14,"end":87},"obj":"Sentence"},{"id":"T19","span":{"begin":88,"end":190},"obj":"Sentence"},{"id":"T20","span":{"begin":191,"end":302},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T18","pred":"source","obj":"sentences"},{"subj":"T19","pred":"source","obj":"sentences"},{"subj":"T20","pred":"source","obj":"sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"sentences","color":"#9cec93","default":true}]}]}}