PMC:2222968 / 2532-2844 JSONTXT

{"project":"sentences","denotations":[{"id":"T18","span":{"begin":14,"end":87},"obj":"Sentence"},{"id":"T19","span":{"begin":88,"end":190},"obj":"Sentence"},{"id":"T20","span":{"begin":191,"end":302},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ed diseases.\n\nIt is shown that Th2 responses prevent the generation of inducible Tregs. This is mediated by IL-4 induction of GATA3, which binds directly to and represses the FOXP3 promoter. This mechanism is likely to be relevant in the induction of immunotolerance, particularly in allergic diseases.\n\nIntroduc"}