PMC:1860061 / 257-580 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1860061","sourcedb":"PMC","sourceid":"1860061","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1860061","text":"are difficult to identify. Here we present a novel strategy to identify the candidate genes for small-effect quantitative trait loci (QTL) in collagen induced arthritis (CIA) using global genome and transcriptome approaches. First, we performed genome linkage analysis in F2 progeny of the CIA susceptible and resistant str","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T497","span":{"begin":0,"end":3},"obj":"VBP"},{"id":"T498","span":{"begin":4,"end":13},"obj":"JJ"},{"id":"T499","span":{"begin":14,"end":16},"obj":"TO"},{"id":"T500","span":{"begin":17,"end":25},"obj":"VB"},{"id":"T501","span":{"begin":25,"end":26},"obj":"."},{"id":"T502","span":{"begin":26,"end":224},"obj":"sentence"},{"id":"T503","span":{"begin":27,"end":31},"obj":"RB"},{"id":"T504","span":{"begin":35,"end":42},"obj":"VBP"},{"id":"T505","span":{"begin":32,"end":34},"obj":"PRP"},{"id":"T506","span":{"begin":43,"end":44},"obj":"DT"},{"id":"T507","span":{"begin":51,"end":59},"obj":"NN"},{"id":"T508","span":{"begin":45,"end":50},"obj":"JJ"},{"id":"T509","span":{"begin":60,"end":62},"obj":"TO"},{"id":"T510","span":{"begin":63,"end":71},"obj":"VB"},{"id":"T511","span":{"begin":72,"end":75},"obj":"DT"},{"id":"T512","span":{"begin":86,"end":91},"obj":"NNS"},{"id":"T513","span":{"begin":76,"end":85},"obj":"NN"},{"id":"T514","span":{"begin":92,"end":95},"obj":"IN"},{"id":"T515","span":{"begin":96,"end":101},"obj":"JJ"},{"id":"T516","span":{"begin":102,"end":108},"obj":"NN"},{"id":"T517","span":{"begin":101,"end":102},"obj":"HYPH"},{"id":"T518","span":{"begin":109,"end":121},"obj":"JJ"},{"id":"T519","span":{"begin":122,"end":127},"obj":"NN"},{"id":"T520","span":{"begin":128,"end":132},"obj":"NNS"},{"id":"T521","span":{"begin":133,"end":134},"obj":"-LRB-"},{"id":"T522","span":{"begin":134,"end":137},"obj":"NN"},{"id":"T523","span":{"begin":137,"end":138},"obj":"-RRB-"},{"id":"T524","span":{"begin":139,"end":141},"obj":"IN"},{"id":"T525","span":{"begin":142,"end":150},"obj":"NN"},{"id":"T526","span":{"begin":151,"end":158},"obj":"VBN"},{"id":"T527","span":{"begin":159,"end":168},"obj":"NN"},{"id":"T528","span":{"begin":169,"end":170},"obj":"-LRB-"},{"id":"T529","span":{"begin":170,"end":173},"obj":"NN"},{"id":"T530","span":{"begin":173,"end":174},"obj":"-RRB-"},{"id":"T531","span":{"begin":175,"end":180},"obj":"VBG"},{"id":"T532","span":{"begin":181,"end":187},"obj":"JJ"},{"id":"T533","span":{"begin":213,"end":223},"obj":"NNS"},{"id":"T534","span":{"begin":188,"end":194},"obj":"NN"},{"id":"T535","span":{"begin":195,"end":198},"obj":"CC"},{"id":"T536","span":{"begin":199,"end":212},"obj":"NN"},{"id":"T537","span":{"begin":223,"end":224},"obj":"."},{"id":"T539","span":{"begin":225,"end":230},"obj":"RB"},{"id":"T540","span":{"begin":235,"end":244},"obj":"VBD"},{"id":"T541","span":{"begin":230,"end":232},"obj":","},{"id":"T542","span":{"begin":232,"end":234},"obj":"PRP"},{"id":"T543","span":{"begin":245,"end":251},"obj":"NN"},{"id":"T544","span":{"begin":252,"end":259},"obj":"NN"},{"id":"T545","span":{"begin":260,"end":268},"obj":"NN"},{"id":"T546","span":{"begin":269,"end":271},"obj":"IN"},{"id":"T547","span":{"begin":272,"end":274},"obj":"NN"},{"id":"T548","span":{"begin":275,"end":282},"obj":"NN"},{"id":"T549","span":{"begin":283,"end":285},"obj":"IN"},{"id":"T550","span":{"begin":286,"end":289},"obj":"DT"},{"id":"T552","span":{"begin":290,"end":293},"obj":"NN"},{"id":"T553","span":{"begin":294,"end":305},"obj":"JJ"},{"id":"T554","span":{"begin":306,"end":309},"obj":"CC"},{"id":"T555","span":{"begin":310,"end":319},"obj":"JJ"}],"relations":[{"id":"R45","pred":"dobj","subj":"T507","obj":"T504"},{"id":"R46","pred":"amod","subj":"T508","obj":"T507"},{"id":"R50","pred":"dobj","subj":"T512","obj":"T510"},{"id":"R51","pred":"compound","subj":"T513","obj":"T512"},{"id":"R54","pred":"pobj","subj":"T516","obj":"T514"},{"id":"R55","pred":"punct","subj":"T517","obj":"T516"},{"id":"R71","pred":"dobj","subj":"T533","obj":"T531"},{"id":"R72","pred":"nmod","subj":"T534","obj":"T533"},{"id":"R73","pred":"cc","subj":"T535","obj":"T534"},{"id":"R74","pred":"conj","subj":"T536","obj":"T534"},{"id":"R88","pred":"npadvmod","subj":"T552","obj":"T553"},{"id":"R90","pred":"cc","subj":"T554","obj":"T553"},{"id":"R91","pred":"conj","subj":"T555","obj":"T553"},{"id":"R38","pred":"acomp","subj":"T498","obj":"T497"},{"id":"R39","pred":"aux","subj":"T499","obj":"T500"},{"id":"R40","pred":"advcl","subj":"T500","obj":"T498"},{"id":"R42","pred":"advmod","subj":"T503","obj":"T504"},{"id":"R43","pred":"nsubj","subj":"T505","obj":"T504"},{"id":"R44","pred":"det","subj":"T506","obj":"T507"},{"id":"R47","pred":"aux","subj":"T509","obj":"T510"},{"id":"R48","pred":"advcl","subj":"T510","obj":"T507"},{"id":"R49","pred":"det","subj":"T511","obj":"T512"},{"id":"R52","pred":"prep","subj":"T514","obj":"T512"},{"id":"R53","pred":"amod","subj":"T515","obj":"T516"},{"id":"R56","pred":"amod","subj":"T518","obj":"T519"},{"id":"R57","pred":"compound","subj":"T519","obj":"T520"},{"id":"R58","pred":"appos","subj":"T520","obj":"T516"},{"id":"R59","pred":"punct","subj":"T521","obj":"T520"},{"id":"R60","pred":"appos","subj":"T522","obj":"T520"},{"id":"R61","pred":"punct","subj":"T523","obj":"T516"},{"id":"R62","pred":"prep","subj":"T524","obj":"T516"},{"id":"R63","pred":"npadvmod","subj":"T525","obj":"T526"},{"id":"R64","pred":"amod","subj":"T526","obj":"T527"},{"id":"R65","pred":"pobj","subj":"T527","obj":"T524"},{"id":"R66","pred":"punct","subj":"T528","obj":"T527"},{"id":"R67","pred":"appos","subj":"T529","obj":"T527"},{"id":"R68","pred":"punct","subj":"T530","obj":"T510"},{"id":"R69","pred":"advcl","subj":"T531","obj":"T510"},{"id":"R70","pred":"amod","subj":"T532","obj":"T533"},{"id":"R75","pred":"punct","subj":"T537","obj":"T504"},{"id":"R76","pred":"advmod","subj":"T539","obj":"T540"},{"id":"R77","pred":"punct","subj":"T541","obj":"T540"},{"id":"R78","pred":"nsubj","subj":"T542","obj":"T540"},{"id":"R79","pred":"compound","subj":"T543","obj":"T544"},{"id":"R80","pred":"compound","subj":"T544","obj":"T545"},{"id":"R81","pred":"dobj","subj":"T545","obj":"T540"},{"id":"R82","pred":"prep","subj":"T546","obj":"T540"},{"id":"R83","pred":"compound","subj":"T547","obj":"T548"},{"id":"R84","pred":"pobj","subj":"T548","obj":"T546"},{"id":"R85","pred":"prep","subj":"T549","obj":"T548"}],"attributes":[{"subj":"T497","pred":"source","obj":"craft-sa-dev"},{"subj":"T498","pred":"source","obj":"craft-sa-dev"},{"subj":"T499","pred":"source","obj":"craft-sa-dev"},{"subj":"T500","pred":"source","obj":"craft-sa-dev"},{"subj":"T501","pred":"source","obj":"craft-sa-dev"},{"subj":"T502","pred":"source","obj":"craft-sa-dev"},{"subj":"T503","pred":"source","obj":"craft-sa-dev"},{"subj":"T504","pred":"source","obj":"craft-sa-dev"},{"subj":"T505","pred":"source","obj":"craft-sa-dev"},{"subj":"T506","pred":"source","obj":"craft-sa-dev"},{"subj":"T507","pred":"source","obj":"craft-sa-dev"},{"subj":"T508","pred":"source","obj":"craft-sa-dev"},{"subj":"T509","pred":"source","obj":"craft-sa-dev"},{"subj":"T510","pred":"source","obj":"craft-sa-dev"},{"subj":"T511","pred":"source","obj":"craft-sa-dev"},{"subj":"T512","pred":"source","obj":"craft-sa-dev"},{"subj":"T513","pred":"source","obj":"craft-sa-dev"},{"subj":"T514","pred":"source","obj":"craft-sa-dev"},{"subj":"T515","pred":"source","obj":"craft-sa-dev"},{"subj":"T516","pred":"source","obj":"craft-sa-dev"},{"subj":"T517","pred":"source","obj":"craft-sa-dev"},{"subj":"T518","pred":"source","obj":"craft-sa-dev"},{"subj":"T519","pred":"source","obj":"craft-sa-dev"},{"subj":"T520","pred":"source","obj":"craft-sa-dev"},{"subj":"T521","pred":"source","obj":"craft-sa-dev"},{"subj":"T522","pred":"source","obj":"craft-sa-dev"},{"subj":"T523","pred":"source","obj":"craft-sa-dev"},{"subj":"T524","pred":"source","obj":"craft-sa-dev"},{"subj":"T525","pred":"source","obj":"craft-sa-dev"},{"subj":"T526","pred":"source","obj":"craft-sa-dev"},{"subj":"T527","pred":"source","obj":"craft-sa-dev"},{"subj":"T528","pred":"source","obj":"craft-sa-dev"},{"subj":"T529","pred":"source","obj":"craft-sa-dev"},{"subj":"T530","pred":"source","obj":"craft-sa-dev"},{"subj":"T531","pred":"source","obj":"craft-sa-dev"},{"subj":"T532","pred":"source","obj":"craft-sa-dev"},{"subj":"T533","pred":"source","obj":"craft-sa-dev"},{"subj":"T534","pred":"source","obj":"craft-sa-dev"},{"subj":"T535","pred":"source","obj":"craft-sa-dev"},{"subj":"T536","pred":"source","obj":"craft-sa-dev"},{"subj":"T537","pred":"source","obj":"craft-sa-dev"},{"subj":"T539","pred":"source","obj":"craft-sa-dev"},{"subj":"T540","pred":"source","obj":"craft-sa-dev"},{"subj":"T541","pred":"source","obj":"craft-sa-dev"},{"subj":"T542","pred":"source","obj":"craft-sa-dev"},{"subj":"T543","pred":"source","obj":"craft-sa-dev"},{"subj":"T544","pred":"source","obj":"craft-sa-dev"},{"subj":"T545","pred":"source","obj":"craft-sa-dev"},{"subj":"T546","pred":"source","obj":"craft-sa-dev"},{"subj":"T547","pred":"source","obj":"craft-sa-dev"},{"subj":"T548","pred":"source","obj":"craft-sa-dev"},{"subj":"T549","pred":"source","obj":"craft-sa-dev"},{"subj":"T550","pred":"source","obj":"craft-sa-dev"},{"subj":"T552","pred":"source","obj":"craft-sa-dev"},{"subj":"T553","pred":"source","obj":"craft-sa-dev"},{"subj":"T554","pred":"source","obj":"craft-sa-dev"},{"subj":"T555","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T436","span":{"begin":86,"end":91},"obj":"SO_EXT:0000704"},{"id":"T437","span":{"begin":109,"end":132},"obj":"SO_EXT:0000771"},{"id":"T438","span":{"begin":134,"end":137},"obj":"SO_EXT:0000771"},{"id":"T439","span":{"begin":142,"end":150},"obj":"CHEBI_PR_EXT:collagen"},{"id":"T440","span":{"begin":188,"end":194},"obj":"SO_EXT:0001026"},{"id":"T441","span":{"begin":245,"end":251},"obj":"SO_EXT:0001026"}],"attributes":[{"subj":"T436","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T437","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T438","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T439","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T440","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T441","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T411","span":{"begin":86,"end":91},"obj":"SO:0000704"},{"id":"T412","span":{"begin":109,"end":132},"obj":"SO:0000771"},{"id":"T413","span":{"begin":134,"end":137},"obj":"SO:0000771"},{"id":"T414","span":{"begin":188,"end":194},"obj":"SO:0001026"},{"id":"T415","span":{"begin":245,"end":251},"obj":"SO:0001026"}],"attributes":[{"subj":"T411","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T412","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T413","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T414","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T415","pred":"source","obj":"craft-ca-core-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#9394ec","default":true},{"id":"craft-ca-core-ex-dev","color":"#aeec93"},{"id":"craft-ca-core-dev","color":"#ec93c8"}]}]}}