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PMC:1626108 / 43740-44582 JSONTXT

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Id Subject Object Predicate Lexical cue
T8483 0-10 NN denotes Hexokinase
T8484 13-18 NN denotes assay
T8485 11-12 CD denotes I
T8486 18-19 . denotes .
T8487 19-266 sentence denotes Hexokinase I activity was determined spectrophotometrically at 25 °C by the method of coupling the glucose-6-phosphate production via glucose-6-phosphate dehydrogenase with the change in the absorbance of NADPH at 340 nm and as described by [66].
T8488 20-30 NN denotes Hexokinase
T8489 33-41 NN denotes activity
T8490 31-32 CD denotes I
T8491 46-56 VBN denotes determined
T8492 42-45 VBD denotes was
T8493 57-79 RB denotes spectrophotometrically
T8494 80-82 IN denotes at
T8495 83-85 CD denotes 25
T8496 86-88 NN denotes °C
T8497 89-91 IN denotes by
T8498 92-95 DT denotes the
T8499 96-102 NN denotes method
T8500 103-105 IN denotes of
T8501 106-114 VBG denotes coupling
T8502 115-118 DT denotes the
T8503 139-149 NN denotes production
T8504 119-126 NN denotes glucose
T8505 129-138 NN denotes phosphate
T8506 126-127 HYPH denotes -
T8507 127-128 CD denotes 6
T8508 128-129 HYPH denotes -
T8509 150-153 IN denotes via
T8510 154-161 NN denotes glucose
T8511 164-173 NN denotes phosphate
T8512 161-162 HYPH denotes -
T8513 162-163 CD denotes 6
T8514 163-164 HYPH denotes -
T8515 174-187 NN denotes dehydrogenase
T8516 188-192 IN denotes with
T8517 193-196 DT denotes the
T8518 197-203 NN denotes change
T8519 204-206 IN denotes in
T8520 207-210 DT denotes the
T8521 211-221 NN denotes absorbance
T8522 222-224 IN denotes of
T8523 225-230 NN denotes NADPH
T8524 231-233 IN denotes at
T8525 234-237 CD denotes 340
T8526 238-240 NN denotes nm
T8527 241-244 CC denotes and
T8528 245-247 IN denotes as
T8529 248-257 VBN denotes described
T8530 258-260 IN denotes by
T8531 261-262 -LRB- denotes [
T8532 262-264 CD denotes 66
T8533 264-265 -RRB- denotes ]
T8534 265-266 . denotes .
T8535 266-552 sentence denotes The reaction was started by the addition of purified brain hexokinase I (0.24 μg) (gift from J. Wilson) to 1.0 ml of reaction mixture containing 0.05 M Tris-HCl (pH 8.5), 7.4 mM MgCl2, 6.6 mM ATP, 0.65 mM NADP, 11.1 mM monothioglycerol, and 1 unit of glucose 6-phosphate dehydrogenase.
T8536 267-270 DT denotes The
T8537 271-279 NN denotes reaction
T8538 284-291 VBN denotes started
T8539 280-283 VBD denotes was
T8540 292-294 IN denotes by
T8541 295-298 DT denotes the
T8542 299-307 NN denotes addition
T8543 308-310 IN denotes of
T8544 311-319 VBN denotes purified
T8545 326-336 NN denotes hexokinase
T8546 320-325 NN denotes brain
T8547 337-338 CD denotes I
T8548 339-340 -LRB- denotes (
T8549 345-347 NNS denotes μg
T8550 340-344 CD denotes 0.24
T8551 347-348 -RRB- denotes )
T8552 349-350 -LRB- denotes (
T8553 350-354 NN denotes gift
T8554 355-359 IN denotes from
T8555 360-362 NNP denotes J.
T8556 363-369 NNP denotes Wilson
T8557 369-370 -RRB- denotes )
T8558 371-373 IN denotes to
T8559 374-377 CD denotes 1.0
T8560 378-380 NN denotes ml
T8561 381-383 IN denotes of
T8562 384-392 NN denotes reaction
T8563 393-400 NN denotes mixture
T8564 401-411 VBG denotes containing
T8565 412-416 CD denotes 0.05
T8566 417-418 NNS denotes M
T8567 424-427 NN denotes HCl
T8568 419-423 NN denotes Tris
T8569 423-424 HYPH denotes -
T8570 428-429 -LRB- denotes (
T8571 429-431 NN denotes pH
T8572 432-435 CD denotes 8.5
T8573 435-436 -RRB- denotes )
T8574 436-438 , denotes ,
T8575 438-441 CD denotes 7.4
T8576 442-444 NNS denotes mM
T8577 445-450 NN denotes MgCl2
T8578 450-452 , denotes ,
T8579 452-455 CD denotes 6.6
T8580 456-458 NNS denotes mM
T8581 459-462 NN denotes ATP
T8582 462-464 , denotes ,
T8583 464-468 CD denotes 0.65
T8584 469-471 NNS denotes mM
T8585 472-476 NN denotes NADP
T8586 476-478 , denotes ,
T8587 478-482 CD denotes 11.1
T8588 483-485 NNS denotes mM
T8589 486-502 NN denotes monothioglycerol
T8590 502-504 , denotes ,
T8591 504-507 CC denotes and
T8592 508-509 CD denotes 1
T8593 510-514 NN denotes unit
T8594 515-517 IN denotes of
T8595 518-525 NN denotes glucose
T8596 528-537 NN denotes phosphate
T8597 526-527 CD denotes 6
T8598 527-528 HYPH denotes -
T8599 538-551 NN denotes dehydrogenase
T8600 551-552 . denotes .
T8601 552-745 sentence denotes In the case of hexokinase activity measured in the presence of Cox11 and LD, the purified HKI was incubated with the recombinant proteins for 15 min at 4 °C before measurement of the activity.
T8602 553-555 IN denotes In
T8603 651-660 VBN denotes incubated
T8604 556-559 DT denotes the
T8605 560-564 NN denotes case
T8606 565-567 IN denotes of
T8607 568-578 NN denotes hexokinase
T8608 579-587 NN denotes activity
T8609 588-596 VBN denotes measured
T8610 597-599 IN denotes in
T8611 600-603 DT denotes the
T8612 604-612 NN denotes presence
T8613 613-615 IN denotes of
T8614 616-621 NN denotes Cox11
T8615 622-625 CC denotes and
T8616 626-628 NN denotes LD
T8617 628-630 , denotes ,
T8618 630-633 DT denotes the
T8619 643-646 NN denotes HKI
T8620 634-642 VBN denotes purified
T8621 647-650 VBD denotes was
T8622 661-665 IN denotes with
T8623 666-669 DT denotes the
T8624 682-690 NN denotes proteins
T8625 670-681 JJ denotes recombinant
T8626 691-694 IN denotes for
T8627 695-697 CD denotes 15
T8628 698-701 NNS denotes min
T8629 702-704 IN denotes at
T8630 705-706 CD denotes 4
T8631 707-709 NN denotes °C
T8632 710-716 IN denotes before
T8633 717-728 NN denotes measurement
T8634 729-731 IN denotes of
T8635 732-735 DT denotes the
T8636 736-744 NN denotes activity
T8637 744-745 . denotes .
T8638 745-842 sentence denotes The data were fitted directly into the Michaelis-Menten equation using SIGMAPLOT (SPSS Science).
T8639 746-749 DT denotes The
T8640 750-754 NNS denotes data
T8641 760-766 VBN denotes fitted
T8642 755-759 VBD denotes were
T8643 767-775 RB denotes directly
T8644 776-780 IN denotes into
T8645 781-784 DT denotes the
T8646 802-810 NN denotes equation
T8647 785-794 NNP denotes Michaelis
T8648 795-801 NNP denotes Menten
T8649 794-795 HYPH denotes -
T8650 811-816 VBG denotes using
T8651 817-826 NNP denotes SIGMAPLOT
T8652 827-828 -LRB- denotes (
T8653 833-840 NNP denotes Science
T8654 828-832 NNP denotes SPSS
T8655 840-841 -RRB- denotes )
T8656 841-842 . denotes .
R5562 T8483 T8484 nmod Hexokinase,assay
R5563 T8485 T8483 nummod I,Hexokinase
R5564 T8486 T8484 punct .,assay
R5565 T8488 T8489 nmod Hexokinase,activity
R5566 T8489 T8491 nsubjpass activity,determined
R5567 T8490 T8488 nummod I,Hexokinase
R5568 T8492 T8491 auxpass was,determined
R5569 T8493 T8491 advmod spectrophotometrically,determined
R5570 T8494 T8491 prep at,determined
R5571 T8495 T8496 nummod 25,°C
R5572 T8496 T8494 pobj °C,at
R5573 T8497 T8491 prep by,determined
R5574 T8498 T8499 det the,method
R5575 T8499 T8497 pobj method,by
R5576 T8500 T8499 prep of,method
R5577 T8501 T8500 pcomp coupling,of
R5578 T8502 T8503 det the,production
R5579 T8503 T8501 dobj production,coupling
R5580 T8504 T8505 nmod glucose,phosphate
R5581 T8505 T8503 compound phosphate,production
R5582 T8506 T8505 punct -,phosphate
R5583 T8507 T8505 nummod 6,phosphate
R5584 T8508 T8505 punct -,phosphate
R5585 T8509 T8503 prep via,production
R5586 T8510 T8511 nmod glucose,phosphate
R5587 T8511 T8515 compound phosphate,dehydrogenase
R5588 T8512 T8511 punct -,phosphate
R5589 T8513 T8511 nummod 6,phosphate
R5590 T8514 T8511 punct -,phosphate
R5591 T8515 T8509 pobj dehydrogenase,via
R5592 T8516 T8501 prep with,coupling
R5593 T8517 T8518 det the,change
R5594 T8518 T8516 pobj change,with
R5595 T8519 T8518 prep in,change
R5596 T8520 T8521 det the,absorbance
R5597 T8521 T8519 pobj absorbance,in
R5598 T8522 T8521 prep of,absorbance
R5599 T8523 T8522 pobj NADPH,of
R5600 T8524 T8518 prep at,change
R5601 T8525 T8526 nummod 340,nm
R5602 T8526 T8524 pobj nm,at
R5603 T8527 T8497 cc and,by
R5604 T8528 T8529 mark as,described
R5605 T8529 T8497 conj described,by
R5606 T8530 T8529 agent by,described
R5607 T8531 T8532 punct [,66
R5608 T8532 T8530 pobj 66,by
R5609 T8533 T8491 punct ],determined
R5610 T8534 T8491 punct .,determined
R5611 T8536 T8537 det The,reaction
R5612 T8537 T8538 nsubjpass reaction,started
R5613 T8539 T8538 auxpass was,started
R5614 T8540 T8538 agent by,started
R5615 T8541 T8542 det the,addition
R5616 T8542 T8540 pobj addition,by
R5617 T8543 T8542 prep of,addition
R5618 T8544 T8545 amod purified,hexokinase
R5619 T8545 T8543 pobj hexokinase,of
R5620 T8546 T8545 compound brain,hexokinase
R5621 T8547 T8545 nummod I,hexokinase
R5622 T8548 T8549 punct (,μg
R5623 T8549 T8545 parataxis μg,hexokinase
R5624 T8550 T8549 nummod 0.24,μg
R5625 T8551 T8549 punct ),μg
R5626 T8552 T8553 punct (,gift
R5627 T8553 T8545 parataxis gift,hexokinase
R5628 T8554 T8553 prep from,gift
R5629 T8555 T8556 compound J.,Wilson
R5630 T8556 T8554 pobj Wilson,from
R5631 T8557 T8553 punct ),gift
R5632 T8558 T8542 prep to,addition
R5633 T8559 T8560 nummod 1.0,ml
R5634 T8560 T8558 pobj ml,to
R5635 T8561 T8560 prep of,ml
R5636 T8562 T8563 compound reaction,mixture
R5637 T8563 T8561 pobj mixture,of
R5638 T8564 T8560 acl containing,ml
R5639 T8565 T8566 nummod 0.05,M
R5640 T8566 T8567 compound M,HCl
R5641 T8567 T8564 dobj HCl,containing
R5642 T8568 T8567 compound Tris,HCl
R5643 T8569 T8567 punct -,HCl
R5644 T8570 T8571 punct (,pH
R5645 T8571 T8567 parataxis pH,HCl
R5646 T8572 T8571 nummod 8.5,pH
R5647 T8573 T8571 punct ),pH
R5648 T8574 T8567 punct ", ",HCl
R5649 T8575 T8576 nummod 7.4,mM
R5650 T8576 T8577 compound mM,MgCl2
R5651 T8577 T8567 conj MgCl2,HCl
R5652 T8578 T8577 punct ", ",MgCl2
R5653 T8579 T8580 nummod 6.6,mM
R5654 T8580 T8581 compound mM,ATP
R5655 T8581 T8577 conj ATP,MgCl2
R5656 T8582 T8581 punct ", ",ATP
R5657 T8583 T8584 nummod 0.65,mM
R5658 T8584 T8585 compound mM,NADP
R5659 T8585 T8581 conj NADP,ATP
R5660 T8586 T8585 punct ", ",NADP
R5661 T8587 T8588 nummod 11.1,mM
R5662 T8588 T8589 compound mM,monothioglycerol
R5663 T8589 T8585 conj monothioglycerol,NADP
R5664 T8590 T8589 punct ", ",monothioglycerol
R5665 T8591 T8589 cc and,monothioglycerol
R5666 T8592 T8593 nummod 1,unit
R5667 T8593 T8589 conj unit,monothioglycerol
R5668 T8594 T8593 prep of,unit
R5669 T8595 T8596 nmod glucose,phosphate
R5670 T8596 T8599 compound phosphate,dehydrogenase
R5671 T8597 T8596 nummod 6,phosphate
R5672 T8598 T8596 punct -,phosphate
R5673 T8599 T8594 pobj dehydrogenase,of
R5674 T8600 T8538 punct .,started
R5675 T8602 T8603 prep In,incubated
R5676 T8604 T8605 det the,case
R5677 T8605 T8602 pobj case,In
R5678 T8606 T8605 prep of,case
R5679 T8607 T8608 compound hexokinase,activity
R5680 T8608 T8606 pobj activity,of
R5681 T8609 T8608 acl measured,activity
R5682 T8610 T8609 prep in,measured
R5683 T8611 T8612 det the,presence
R5684 T8612 T8610 pobj presence,in
R5685 T8613 T8612 prep of,presence
R5686 T8614 T8613 pobj Cox11,of
R5687 T8615 T8614 cc and,Cox11
R5688 T8616 T8614 conj LD,Cox11
R5689 T8617 T8603 punct ", ",incubated
R5690 T8618 T8619 det the,HKI
R5691 T8619 T8603 nsubjpass HKI,incubated
R5692 T8620 T8619 amod purified,HKI
R5693 T8621 T8603 auxpass was,incubated
R5694 T8622 T8603 prep with,incubated
R5695 T8623 T8624 det the,proteins
R5696 T8624 T8622 pobj proteins,with
R5697 T8625 T8624 amod recombinant,proteins
R5698 T8626 T8603 prep for,incubated
R5699 T8627 T8628 nummod 15,min
R5700 T8628 T8626 pobj min,for
R5701 T8629 T8603 prep at,incubated
R5702 T8630 T8631 nummod 4,°C
R5703 T8631 T8629 pobj °C,at
R5704 T8632 T8603 prep before,incubated
R5705 T8633 T8632 pobj measurement,before
R5706 T8634 T8633 prep of,measurement
R5707 T8635 T8636 det the,activity
R5708 T8636 T8634 pobj activity,of
R5709 T8637 T8603 punct .,incubated
R5710 T8639 T8640 det The,data
R5711 T8640 T8641 nsubjpass data,fitted
R5712 T8642 T8641 auxpass were,fitted
R5713 T8643 T8641 advmod directly,fitted
R5714 T8644 T8641 prep into,fitted
R5715 T8645 T8646 det the,equation
R5716 T8646 T8644 pobj equation,into
R5717 T8647 T8648 compound Michaelis,Menten
R5718 T8648 T8646 compound Menten,equation
R5719 T8649 T8648 punct -,Menten
R5720 T8650 T8641 advcl using,fitted
R5721 T8651 T8650 dobj SIGMAPLOT,using
R5722 T8652 T8653 punct (,Science
R5723 T8653 T8651 parataxis Science,SIGMAPLOT
R5724 T8654 T8653 compound SPSS,Science
R5725 T8655 T8653 punct ),Science
R5726 T8656 T8641 punct .,fitted

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T8472 445-450 CHEBI:6636 denotes MgCl2
T8458 0-10 GO_EXT:0004396 denotes Hexokinase
T8459 0-12 PR_EXT:000008608 denotes Hexokinase I
T8460 20-30 GO_EXT:0004396 denotes Hexokinase
T8461 20-32 PR_EXT:000008608 denotes Hexokinase I
T8462 119-138 CHEBI:14314 denotes glucose-6-phosphate
T8463 154-173 CHEBI:14314 denotes glucose-6-phosphate
T8464 154-187 GO_PR_EXT:glucose_6_phosphate_dehydrogenase denotes glucose-6-phosphate dehydrogenase
T8465 225-230 CHEBI_EXT:NADPH denotes NADPH
T8466 320-325 UBERON:0000955 denotes brain
T8467 320-338 PR_EXT:000008608 denotes brain hexokinase I
T8468 326-336 GO_EXT:0004396 denotes hexokinase
T8469 393-400 CHEBI:60004 denotes mixture
T8470 419-423 CHEBI:9754 denotes Tris
T8471 424-427 CHEBI:17883 denotes HCl
T8473 459-462 CHEBI_EXT:ATP denotes ATP
T8474 472-476 CHEBI_EXT:NADP denotes NADP
T8475 486-502 CHEBI:74537 denotes monothioglycerol
T8476 518-537 CHEBI:14314 denotes glucose 6-phosphate
T8477 518-551 GO_PR_EXT:glucose_6_phosphate_dehydrogenase denotes glucose 6-phosphate dehydrogenase
T8478 568-578 GO_EXT:0004396 denotes hexokinase
T8479 616-621 PR_EXT:000005770 denotes Cox11
T8480 643-646 PR_EXT:000008608 denotes HKI
T8481 670-681 GO_SO_EXT:sequence_rearrangement_process denotes recombinant
T8482 682-690 CHEBI_PR_EXT:protein denotes proteins

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T8444 0-12 PR:000008608 denotes Hexokinase I
T8445 20-32 PR:000008608 denotes Hexokinase I
T8446 119-138 CHEBI:14314 denotes glucose-6-phosphate
T8447 154-173 CHEBI:14314 denotes glucose-6-phosphate
T8448 320-325 UBERON:0000955 denotes brain
T8449 320-338 PR:000008608 denotes brain hexokinase I
T8450 393-400 CHEBI:60004 denotes mixture
T8451 419-423 CHEBI:9754 denotes Tris
T8452 424-427 CHEBI:17883 denotes HCl
T8453 445-450 CHEBI:6636 denotes MgCl2
T8454 486-502 CHEBI:74537 denotes monothioglycerol
T8455 518-537 CHEBI:14314 denotes glucose 6-phosphate
T8456 616-621 PR:000005770 denotes Cox11
T8457 643-646 PR:000008608 denotes HKI

2_test

Id Subject Object Predicate Lexical cue
17069463-2740289-85858879 262-264 2740289 denotes 66
T67368 262-264 2740289 denotes 66