PMC:1540739 / 213-476 JSONTXT

Annnotations TAB JSON ListView MergeView

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1540739","sourcedb":"PMC","sourceid":"1540739","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1540739","text":"using homologous recombination in ES cells to generate mutant mice. Although informative, this approach is inefficient, slow and expensive. To facilitate targeting at the p53 locus, we developed an improved Recombinase-Mediated Cassette Exchange (RMCE) method. Ou","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T479","span":{"begin":0,"end":5},"obj":"VBG"},{"id":"T480","span":{"begin":6,"end":16},"obj":"JJ"},{"id":"T481","span":{"begin":17,"end":30},"obj":"NN"},{"id":"T482","span":{"begin":31,"end":33},"obj":"IN"},{"id":"T483","span":{"begin":34,"end":36},"obj":"NN"},{"id":"T484","span":{"begin":37,"end":42},"obj":"NNS"},{"id":"T485","span":{"begin":43,"end":45},"obj":"TO"},{"id":"T486","span":{"begin":46,"end":54},"obj":"VB"},{"id":"T487","span":{"begin":55,"end":61},"obj":"JJ"},{"id":"T488","span":{"begin":62,"end":66},"obj":"NNS"},{"id":"T489","span":{"begin":66,"end":67},"obj":"."},{"id":"T490","span":{"begin":67,"end":139},"obj":"sentence"},{"id":"T491","span":{"begin":68,"end":76},"obj":"IN"},{"id":"T492","span":{"begin":77,"end":88},"obj":"JJ"},{"id":"T493","span":{"begin":104,"end":106},"obj":"VBZ"},{"id":"T494","span":{"begin":88,"end":90},"obj":","},{"id":"T495","span":{"begin":90,"end":94},"obj":"DT"},{"id":"T496","span":{"begin":95,"end":103},"obj":"NN"},{"id":"T497","span":{"begin":107,"end":118},"obj":"JJ"},{"id":"T498","span":{"begin":118,"end":120},"obj":","},{"id":"T499","span":{"begin":120,"end":124},"obj":"JJ"},{"id":"T500","span":{"begin":125,"end":128},"obj":"CC"},{"id":"T501","span":{"begin":129,"end":138},"obj":"JJ"},{"id":"T502","span":{"begin":138,"end":139},"obj":"."},{"id":"T503","span":{"begin":139,"end":260},"obj":"sentence"},{"id":"T504","span":{"begin":140,"end":142},"obj":"TO"},{"id":"T505","span":{"begin":143,"end":153},"obj":"VB"},{"id":"T506","span":{"begin":185,"end":194},"obj":"VBD"},{"id":"T507","span":{"begin":154,"end":163},"obj":"NN"},{"id":"T508","span":{"begin":164,"end":166},"obj":"IN"},{"id":"T509","span":{"begin":167,"end":170},"obj":"DT"},{"id":"T510","span":{"begin":175,"end":180},"obj":"NN"},{"id":"T511","span":{"begin":171,"end":174},"obj":"NN"},{"id":"T512","span":{"begin":180,"end":182},"obj":","},{"id":"T513","span":{"begin":182,"end":184},"obj":"PRP"},{"id":"T514","span":{"begin":195,"end":197},"obj":"DT"},{"id":"T515","span":{"begin":253,"end":259},"obj":"NN"},{"id":"T516","span":{"begin":198,"end":206},"obj":"VBN"},{"id":"T517","span":{"begin":207,"end":218},"obj":"NN"},{"id":"T518","span":{"begin":219,"end":227},"obj":"JJ"},{"id":"T519","span":{"begin":218,"end":219},"obj":"HYPH"},{"id":"T520","span":{"begin":237,"end":245},"obj":"NNP"},{"id":"T521","span":{"begin":228,"end":236},"obj":"NNP"},{"id":"T522","span":{"begin":246,"end":247},"obj":"-LRB-"},{"id":"T523","span":{"begin":247,"end":251},"obj":"NN"},{"id":"T524","span":{"begin":251,"end":252},"obj":"-RRB-"},{"id":"T525","span":{"begin":259,"end":260},"obj":"."}],"relations":[{"id":"R39","pred":"amod","subj":"T480","obj":"T481"},{"id":"R40","pred":"dobj","subj":"T481","obj":"T479"},{"id":"R41","pred":"prep","subj":"T482","obj":"T479"},{"id":"R42","pred":"compound","subj":"T483","obj":"T484"},{"id":"R43","pred":"pobj","subj":"T484","obj":"T482"},{"id":"R44","pred":"aux","subj":"T485","obj":"T486"},{"id":"R45","pred":"advcl","subj":"T486","obj":"T479"},{"id":"R46","pred":"amod","subj":"T487","obj":"T488"},{"id":"R47","pred":"dobj","subj":"T488","obj":"T486"},{"id":"R49","pred":"mark","subj":"T491","obj":"T492"},{"id":"R50","pred":"advcl","subj":"T492","obj":"T493"},{"id":"R51","pred":"punct","subj":"T494","obj":"T493"},{"id":"R52","pred":"det","subj":"T495","obj":"T496"},{"id":"R53","pred":"nsubj","subj":"T496","obj":"T493"},{"id":"R54","pred":"acomp","subj":"T497","obj":"T493"},{"id":"R55","pred":"punct","subj":"T498","obj":"T497"},{"id":"R56","pred":"conj","subj":"T499","obj":"T497"},{"id":"R57","pred":"cc","subj":"T500","obj":"T499"},{"id":"R58","pred":"conj","subj":"T501","obj":"T499"},{"id":"R59","pred":"punct","subj":"T502","obj":"T493"},{"id":"R60","pred":"aux","subj":"T504","obj":"T505"},{"id":"R61","pred":"advcl","subj":"T505","obj":"T506"},{"id":"R62","pred":"dobj","subj":"T507","obj":"T505"},{"id":"R63","pred":"prep","subj":"T508","obj":"T505"},{"id":"R64","pred":"det","subj":"T509","obj":"T510"},{"id":"R65","pred":"pobj","subj":"T510","obj":"T508"},{"id":"R66","pred":"compound","subj":"T511","obj":"T510"},{"id":"R67","pred":"punct","subj":"T512","obj":"T506"},{"id":"R68","pred":"nsubj","subj":"T513","obj":"T506"},{"id":"R69","pred":"det","subj":"T514","obj":"T515"},{"id":"R70","pred":"dobj","subj":"T515","obj":"T506"},{"id":"R71","pred":"amod","subj":"T516","obj":"T515"},{"id":"R72","pred":"npadvmod","subj":"T517","obj":"T518"},{"id":"R73","pred":"amod","subj":"T518","obj":"T520"},{"id":"R74","pred":"punct","subj":"T519","obj":"T518"},{"id":"R75","pred":"nmod","subj":"T520","obj":"T515"},{"id":"R76","pred":"nmod","subj":"T521","obj":"T520"},{"id":"R77","pred":"punct","subj":"T522","obj":"T520"},{"id":"R78","pred":"appos","subj":"T523","obj":"T520"},{"id":"R79","pred":"punct","subj":"T524","obj":"T515"},{"id":"R80","pred":"punct","subj":"T525","obj":"T506"}],"attributes":[{"subj":"T479","pred":"source","obj":"craft-sa-dev"},{"subj":"T480","pred":"source","obj":"craft-sa-dev"},{"subj":"T481","pred":"source","obj":"craft-sa-dev"},{"subj":"T482","pred":"source","obj":"craft-sa-dev"},{"subj":"T483","pred":"source","obj":"craft-sa-dev"},{"subj":"T484","pred":"source","obj":"craft-sa-dev"},{"subj":"T485","pred":"source","obj":"craft-sa-dev"},{"subj":"T486","pred":"source","obj":"craft-sa-dev"},{"subj":"T487","pred":"source","obj":"craft-sa-dev"},{"subj":"T488","pred":"source","obj":"craft-sa-dev"},{"subj":"T489","pred":"source","obj":"craft-sa-dev"},{"subj":"T490","pred":"source","obj":"craft-sa-dev"},{"subj":"T491","pred":"source","obj":"craft-sa-dev"},{"subj":"T492","pred":"source","obj":"craft-sa-dev"},{"subj":"T493","pred":"source","obj":"craft-sa-dev"},{"subj":"T494","pred":"source","obj":"craft-sa-dev"},{"subj":"T495","pred":"source","obj":"craft-sa-dev"},{"subj":"T496","pred":"source","obj":"craft-sa-dev"},{"subj":"T497","pred":"source","obj":"craft-sa-dev"},{"subj":"T498","pred":"source","obj":"craft-sa-dev"},{"subj":"T499","pred":"source","obj":"craft-sa-dev"},{"subj":"T500","pred":"source","obj":"craft-sa-dev"},{"subj":"T501","pred":"source","obj":"craft-sa-dev"},{"subj":"T502","pred":"source","obj":"craft-sa-dev"},{"subj":"T503","pred":"source","obj":"craft-sa-dev"},{"subj":"T504","pred":"source","obj":"craft-sa-dev"},{"subj":"T505","pred":"source","obj":"craft-sa-dev"},{"subj":"T506","pred":"source","obj":"craft-sa-dev"},{"subj":"T507","pred":"source","obj":"craft-sa-dev"},{"subj":"T508","pred":"source","obj":"craft-sa-dev"},{"subj":"T509","pred":"source","obj":"craft-sa-dev"},{"subj":"T510","pred":"source","obj":"craft-sa-dev"},{"subj":"T511","pred":"source","obj":"craft-sa-dev"},{"subj":"T512","pred":"source","obj":"craft-sa-dev"},{"subj":"T513","pred":"source","obj":"craft-sa-dev"},{"subj":"T514","pred":"source","obj":"craft-sa-dev"},{"subj":"T515","pred":"source","obj":"craft-sa-dev"},{"subj":"T516","pred":"source","obj":"craft-sa-dev"},{"subj":"T517","pred":"source","obj":"craft-sa-dev"},{"subj":"T518","pred":"source","obj":"craft-sa-dev"},{"subj":"T519","pred":"source","obj":"craft-sa-dev"},{"subj":"T520","pred":"source","obj":"craft-sa-dev"},{"subj":"T521","pred":"source","obj":"craft-sa-dev"},{"subj":"T522","pred":"source","obj":"craft-sa-dev"},{"subj":"T523","pred":"source","obj":"craft-sa-dev"},{"subj":"T524","pred":"source","obj":"craft-sa-dev"},{"subj":"T525","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T413","span":{"begin":17,"end":30},"obj":"GO_SO_EXT:sequence_rearrangement_process"},{"id":"T414","span":{"begin":34,"end":42},"obj":"CL:0002322"},{"id":"T415","span":{"begin":37,"end":42},"obj":"CL_GO_EXT:cell"},{"id":"T416","span":{"begin":55,"end":61},"obj":"SO_EXT:sequence_altered_entity_or_alteration_process"},{"id":"T417","span":{"begin":62,"end":66},"obj":"NCBITaxon:10088"},{"id":"T418","span":{"begin":171,"end":174},"obj":"PR_EXT:000003035"},{"id":"T419","span":{"begin":207,"end":218},"obj":"GO_EXT:recombinase"},{"id":"T420","span":{"begin":228,"end":236},"obj":"SO_EXT:0005853"},{"id":"T421","span":{"begin":237,"end":245},"obj":"SO_EXT:sequence_substitution_process"}],"attributes":[{"subj":"T413","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T414","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T415","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T416","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T417","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T418","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T419","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T420","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T421","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T391","span":{"begin":34,"end":42},"obj":"CL:0002322"},{"id":"T392","span":{"begin":62,"end":66},"obj":"NCBITaxon:10088"},{"id":"T393","span":{"begin":171,"end":174},"obj":"PR:000003035"},{"id":"T394","span":{"begin":228,"end":236},"obj":"SO:0005853"}],"attributes":[{"subj":"T391","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T392","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T393","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T394","pred":"source","obj":"craft-ca-core-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#c0ec93","default":true},{"id":"craft-ca-core-ex-dev","color":"#ec93da"},{"id":"craft-ca-core-dev","color":"#93ece4"}]}]}}