PMC:1540739 / 1629-2219 JSONTXT

Annnotations TAB JSON ListView MergeView

    craft-sa-dev

    {"project":"craft-sa-dev","denotations":[{"id":"T2663","span":{"begin":9,"end":16},"obj":"NN"},{"id":"T2664","span":{"begin":1,"end":8},"obj":"JJ"},{"id":"T2665","span":{"begin":17,"end":20},"obj":"CC"},{"id":"T2666","span":{"begin":21,"end":30},"obj":"VBN"},{"id":"T2667","span":{"begin":31,"end":35},"obj":"IN"},{"id":"T2668","span":{"begin":36,"end":39},"obj":"DT"},{"id":"T2669","span":{"begin":51,"end":59},"obj":"NN"},{"id":"T2670","span":{"begin":40,"end":50},"obj":"JJ"},{"id":"T2671","span":{"begin":59,"end":61},"obj":","},{"id":"T2672","span":{"begin":61,"end":69},"obj":"VBG"},{"id":"T2673","span":{"begin":70,"end":83},"obj":"JJ"},{"id":"T2674","span":{"begin":95,"end":101},"obj":"NNS"},{"id":"T2675","span":{"begin":84,"end":94},"obj":"NN"},{"id":"T2676","span":{"begin":102,"end":105},"obj":"CC"},{"id":"T2677","span":{"begin":106,"end":113},"obj":"JJ"},{"id":"T2678","span":{"begin":130,"end":138},"obj":"NNS"},{"id":"T2679","span":{"begin":114,"end":120},"obj":"JJ"},{"id":"T2680","span":{"begin":121,"end":129},"obj":"JJ"},{"id":"T2681","span":{"begin":120,"end":121},"obj":"HYPH"},{"id":"T2682","span":{"begin":138,"end":139},"obj":"."},{"id":"T2683","span":{"begin":139,"end":405},"obj":"sentence"},{"id":"T2684","span":{"begin":140,"end":142},"obj":"IN"},{"id":"T2685","span":{"begin":247,"end":255},"obj":"VBN"},{"id":"T2686","span":{"begin":143,"end":154},"obj":"JJ"},{"id":"T2687","span":{"begin":155,"end":166},"obj":"NNS"},{"id":"T2688","span":{"begin":167,"end":174},"obj":"IN"},{"id":"T2689","span":{"begin":175,"end":185},"obj":"NNS"},{"id":"T2690","span":{"begin":186,"end":190},"obj":"IN"},{"id":"T2691","span":{"begin":191,"end":199},"obj":"VBN"},{"id":"T2692","span":{"begin":204,"end":211},"obj":"NNS"},{"id":"T2693","span":{"begin":200,"end":203},"obj":"NN"},{"id":"T2694","span":{"begin":212,"end":214},"obj":"FW"},{"id":"T2695","span":{"begin":215,"end":219},"obj":"FW"},{"id":"T2696","span":{"begin":220,"end":223},"obj":"CC"},{"id":"T2697","span":{"begin":224,"end":236},"obj":"NN"},{"id":"T2698","span":{"begin":237,"end":241},"obj":"NNS"},{"id":"T2699","span":{"begin":242,"end":246},"obj":"VBD"},{"id":"T2700","span":{"begin":299,"end":303},"obj":"VBP"},{"id":"T2701","span":{"begin":256,"end":257},"obj":"-LRB-"},{"id":"T2702","span":{"begin":268,"end":269},"obj":"CD"},{"id":"T2703","span":{"begin":257,"end":261},"obj":"FW"},{"id":"T2704","span":{"begin":262,"end":266},"obj":"NNS"},{"id":"T2705","span":{"begin":267,"end":268},"obj":"-LRB-"},{"id":"T2706","span":{"begin":269,"end":270},"obj":"SYM"},{"id":"T2707","span":{"begin":270,"end":271},"obj":"CD"},{"id":"T2708","span":{"begin":271,"end":272},"obj":"-RRB-"},{"id":"T2709","span":{"begin":272,"end":273},"obj":"-RRB-"},{"id":"T2710","span":{"begin":273,"end":275},"obj":","},{"id":"T2711","span":{"begin":275,"end":279},"obj":"RBR"},{"id":"T2712","span":{"begin":280,"end":288},"obj":"VBN"},{"id":"T2713","span":{"begin":289,"end":298},"obj":"NNS"},{"id":"T2714","span":{"begin":304,"end":306},"obj":"TO"},{"id":"T2715","span":{"begin":310,"end":319},"obj":"VBN"},{"id":"T2716","span":{"begin":307,"end":309},"obj":"VB"},{"id":"T2717","span":{"begin":320,"end":323},"obj":"CC"},{"id":"T2718","span":{"begin":324,"end":332},"obj":"VBN"},{"id":"T2719","span":{"begin":333,"end":335},"obj":"IN"},{"id":"T2720","span":{"begin":336,"end":344},"obj":"JJ"},{"id":"T2721","span":{"begin":345,"end":352},"obj":"NNS"},{"id":"T2722","span":{"begin":353,"end":355},"obj":"TO"},{"id":"T2723","span":{"begin":356,"end":365},"obj":"VB"},{"id":"T2724","span":{"begin":366,"end":370},"obj":"RBR"},{"id":"T2725","span":{"begin":371,"end":379},"obj":"JJ"},{"id":"T2726","span":{"begin":380,"end":386},"obj":"NNS"},{"id":"T2727","span":{"begin":387,"end":389},"obj":"IN"},{"id":"T2728","span":{"begin":390,"end":393},"obj":"NN"},{"id":"T2729","span":{"begin":394,"end":404},"obj":"NN"},{"id":"T2730","span":{"begin":404,"end":405},"obj":"."},{"id":"T2732","span":{"begin":406,"end":413},"obj":"RB"},{"id":"T2733","span":{"begin":482,"end":484},"obj":"VBZ"},{"id":"T2734","span":{"begin":413,"end":415},"obj":","},{"id":"T2735","span":{"begin":415,"end":420},"obj":"VBG"},{"id":"T2736","span":{"begin":421,"end":431},"obj":"JJ"},{"id":"T2737","span":{"begin":432,"end":445},"obj":"NN"},{"id":"T2738","span":{"begin":446,"end":448},"obj":"IN"},{"id":"T2739","span":{"begin":449,"end":451},"obj":"NN"},{"id":"T2740","span":{"begin":452,"end":457},"obj":"NNS"},{"id":"T2741","span":{"begin":458,"end":460},"obj":"TO"},{"id":"T2742","span":{"begin":461,"end":469},"obj":"VB"},{"id":"T2743","span":{"begin":470,"end":476},"obj":"JJ"},{"id":"T2744","span":{"begin":477,"end":481},"obj":"NNS"},{"id":"T2745","span":{"begin":485,"end":487},"obj":"DT"},{"id":"T2746","span":{"begin":520,"end":526},"obj":"NN"},{"id":"T2747","span":{"begin":488,"end":499},"obj":"JJ"},{"id":"T2748","span":{"begin":499,"end":501},"obj":","},{"id":"T2749","span":{"begin":501,"end":505},"obj":"JJ"},{"id":"T2750","span":{"begin":506,"end":509},"obj":"CC"},{"id":"T2751","span":{"begin":510,"end":519},"obj":"JJ"},{"id":"T2752","span":{"begin":527,"end":534},"obj":"IN"},{"id":"T2753","span":{"begin":574,"end":580},"obj":"VBZ"},{"id":"T2754","span":{"begin":535,"end":536},"obj":"-LRB-"},{"id":"T2755","span":{"begin":536,"end":537},"obj":"LS"},{"id":"T2756","span":{"begin":537,"end":538},"obj":"-RRB-"},{"id":"T2757","span":{"begin":539,"end":549},"obj":"JJ"},{"id":"T2758","span":{"begin":550,"end":563},"obj":"NN"},{"id":"T2759","span":{"begin":564,"end":573},"obj":"RB"},{"id":"T2760","span":{"begin":581,"end":583},"obj":"IN"},{"id":"T2761","span":{"begin":584,"end":587},"obj":"JJ"}],"relations":[{"id":"R262","pred":"advmod","subj":"T2695","obj":"T2690"},{"id":"R264","pred":"cc","subj":"T2696","obj":"T2689"},{"id":"R266","pred":"compound","subj":"T2697","obj":"T2698"},{"id":"R267","pred":"conj","subj":"T2698","obj":"T2689"},{"id":"R269","pred":"auxpass","subj":"T2699","obj":"T2685"},{"id":"R271","pred":"punct","subj":"T2701","obj":"T2702"},{"id":"R272","pred":"parataxis","subj":"T2702","obj":"T2685"},{"id":"R273","pred":"advmod","subj":"T2703","obj":"T2702"},{"id":"R275","pred":"nmod","subj":"T2704","obj":"T2702"},{"id":"R276","pred":"punct","subj":"T2705","obj":"T2702"},{"id":"R278","pred":"punct","subj":"T2706","obj":"T2707"},{"id":"R279","pred":"prep","subj":"T2707","obj":"T2702"},{"id":"R280","pred":"punct","subj":"T2708","obj":"T2702"},{"id":"R282","pred":"punct","subj":"T2709","obj":"T2702"},{"id":"R284","pred":"punct","subj":"T2710","obj":"T2700"},{"id":"R286","pred":"advmod","subj":"T2711","obj":"T2712"},{"id":"R287","pred":"amod","subj":"T2712","obj":"T2713"},{"id":"R289","pred":"nsubj","subj":"T2713","obj":"T2700"},{"id":"R290","pred":"aux","subj":"T2714","obj":"T2715"},{"id":"R291","pred":"xcomp","subj":"T2715","obj":"T2700"},{"id":"R292","pred":"auxpass","subj":"T2716","obj":"T2715"},{"id":"R294","pred":"cc","subj":"T2717","obj":"T2715"},{"id":"R295","pred":"conj","subj":"T2718","obj":"T2715"},{"id":"R297","pred":"prep","subj":"T2719","obj":"T2718"},{"id":"R298","pred":"amod","subj":"T2720","obj":"T2721"},{"id":"R299","pred":"pobj","subj":"T2721","obj":"T2719"},{"id":"R300","pred":"aux","subj":"T2722","obj":"T2723"},{"id":"R301","pred":"advcl","subj":"T2723","obj":"T2718"},{"id":"R302","pred":"advmod","subj":"T2724","obj":"T2725"},{"id":"R304","pred":"amod","subj":"T2725","obj":"T2726"},{"id":"R306","pred":"dobj","subj":"T2726","obj":"T2723"},{"id":"R307","pred":"prep","subj":"T2727","obj":"T2726"},{"id":"R308","pred":"compound","subj":"T2728","obj":"T2729"},{"id":"R309","pred":"pobj","subj":"T2729","obj":"T2727"},{"id":"R310","pred":"punct","subj":"T2730","obj":"T2700"},{"id":"R312","pred":"advmod","subj":"T2732","obj":"T2733"},{"id":"R314","pred":"punct","subj":"T2734","obj":"T2733"},{"id":"R315","pred":"csubj","subj":"T2735","obj":"T2733"},{"id":"R317","pred":"amod","subj":"T2736","obj":"T2737"},{"id":"R319","pred":"dobj","subj":"T2737","obj":"T2735"},{"id":"R320","pred":"prep","subj":"T2738","obj":"T2735"},{"id":"R322","pred":"compound","subj":"T2739","obj":"T2740"},{"id":"R323","pred":"pobj","subj":"T2740","obj":"T2738"},{"id":"R324","pred":"aux","subj":"T2741","obj":"T2742"},{"id":"R326","pred":"advcl","subj":"T2742","obj":"T2735"},{"id":"R327","pred":"amod","subj":"T2743","obj":"T2744"},{"id":"R328","pred":"dobj","subj":"T2744","obj":"T2742"},{"id":"R329","pred":"det","subj":"T2745","obj":"T2746"},{"id":"R331","pred":"attr","subj":"T2746","obj":"T2733"},{"id":"R332","pred":"amod","subj":"T2747","obj":"T2746"},{"id":"R333","pred":"punct","subj":"T2748","obj":"T2747"},{"id":"R335","pred":"conj","subj":"T2749","obj":"T2747"},{"id":"R336","pred":"cc","subj":"T2750","obj":"T2749"},{"id":"R338","pred":"conj","subj":"T2751","obj":"T2749"},{"id":"R339","pred":"mark","subj":"T2752","obj":"T2753"},{"id":"R340","pred":"advcl","subj":"T2753","obj":"T2733"},{"id":"R342","pred":"punct","subj":"T2754","obj":"T2755"},{"id":"R343","pred":"meta","subj":"T2755","obj":"T2753"},{"id":"R344","pred":"punct","subj":"T2756","obj":"T2755"},{"id":"R345","pred":"amod","subj":"T2757","obj":"T2758"},{"id":"R347","pred":"nsubj","subj":"T2758","obj":"T2753"},{"id":"R348","pred":"advmod","subj":"T2759","obj":"T2753"},{"id":"R349","pred":"prep","subj":"T2760","obj":"T2753"},{"id":"R365","pred":"amod","subj":"T2664","obj":"T2663"},{"id":"R376","pred":"prep","subj":"T2667","obj":"T2666"},{"id":"R380","pred":"det","subj":"T2668","obj":"T2669"},{"id":"R382","pred":"pobj","subj":"T2669","obj":"T2667"},{"id":"R385","pred":"amod","subj":"T2670","obj":"T2669"},{"id":"R398","pred":"amod","subj":"T2673","obj":"T2674"},{"id":"R401","pred":"dobj","subj":"T2674","obj":"T2672"},{"id":"R404","pred":"compound","subj":"T2675","obj":"T2674"},{"id":"R405","pred":"cc","subj":"T2676","obj":"T2674"},{"id":"R407","pred":"amod","subj":"T2677","obj":"T2678"},{"id":"R410","pred":"conj","subj":"T2678","obj":"T2674"},{"id":"R414","pred":"amod","subj":"T2679","obj":"T2680"},{"id":"R417","pred":"amod","subj":"T2680","obj":"T2678"},{"id":"R421","pred":"punct","subj":"T2681","obj":"T2680"},{"id":"R428","pred":"mark","subj":"T2684","obj":"T2685"},{"id":"R434","pred":"advcl","subj":"T2685","obj":"T2700"},{"id":"R438","pred":"amod","subj":"T2686","obj":"T2687"},{"id":"R440","pred":"nsubjpass","subj":"T2687","obj":"T2685"},{"id":"R443","pred":"prep","subj":"T2688","obj":"T2687"},{"id":"R447","pred":"pobj","subj":"T2689","obj":"T2688"},{"id":"R451","pred":"prep","subj":"T2690","obj":"T2689"},{"id":"R455","pred":"amod","subj":"T2691","obj":"T2692"},{"id":"R461","pred":"pobj","subj":"T2692","obj":"T2690"},{"id":"R463","pred":"compound","subj":"T2693","obj":"T2692"},{"id":"R467","pred":"advmod","subj":"T2694","obj":"T2695"}],"text":" genomic setting and expressed from the endogenous promoter, ensuring physiological expression levels and correct spatio-temporal profiles. As significant differences between phenotypes from targeted p53 mutants in vivo and transfection data were observed [e.g. Refs (1–5)], more targeted mutations need to be generated and analyzed in multiple tissues to formulate more accurate models of p53 regulation.\nHowever, using homologous recombination in ES cells to generate mutant mice is an inefficient, slow and expensive method because (i) homologous recombination typically occurs at low fr"}

    craft-ca-core-ex-dev

    {"project":"craft-ca-core-ex-dev","denotations":[{"id":"T2436","span":{"begin":1,"end":8},"obj":"SO_EXT:0001026"},{"id":"T2437","span":{"begin":21,"end":30},"obj":"GO:0010467"},{"id":"T2438","span":{"begin":51,"end":59},"obj":"SO_EXT:0000167"},{"id":"T2439","span":{"begin":70,"end":83},"obj":"GO_PATO_EXT:physiological_process_or_quality"},{"id":"T2440","span":{"begin":84,"end":94},"obj":"GO:0010467"},{"id":"T2441","span":{"begin":200,"end":203},"obj":"PR_EXT:000003035"},{"id":"T2442","span":{"begin":204,"end":211},"obj":"SO_EXT:sequence_altered_entity"},{"id":"T2443","span":{"begin":224,"end":236},"obj":"GO:0009294"},{"id":"T2444","span":{"begin":289,"end":298},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T2445","span":{"begin":390,"end":393},"obj":"PR_EXT:000003035"},{"id":"T2446","span":{"begin":394,"end":404},"obj":"GO:0065007"},{"id":"T2447","span":{"begin":432,"end":445},"obj":"GO_SO_EXT:sequence_rearrangement_process"},{"id":"T2448","span":{"begin":449,"end":457},"obj":"CL:0002322"},{"id":"T2449","span":{"begin":452,"end":457},"obj":"CL_GO_EXT:cell"},{"id":"T2450","span":{"begin":470,"end":476},"obj":"SO_EXT:sequence_altered_entity_or_alteration_process"},{"id":"T2451","span":{"begin":477,"end":481},"obj":"NCBITaxon:10088"},{"id":"T2452","span":{"begin":550,"end":563},"obj":"GO_SO_EXT:sequence_rearrangement_process"}],"text":" genomic setting and expressed from the endogenous promoter, ensuring physiological expression levels and correct spatio-temporal profiles. As significant differences between phenotypes from targeted p53 mutants in vivo and transfection data were observed [e.g. Refs (1–5)], more targeted mutations need to be generated and analyzed in multiple tissues to formulate more accurate models of p53 regulation.\nHowever, using homologous recombination in ES cells to generate mutant mice is an inefficient, slow and expensive method because (i) homologous recombination typically occurs at low fr"}

    craft-ca-core-dev

    {"project":"craft-ca-core-dev","denotations":[{"id":"T2344","span":{"begin":1,"end":8},"obj":"SO:0001026"},{"id":"T2345","span":{"begin":21,"end":30},"obj":"GO:0010467"},{"id":"T2346","span":{"begin":51,"end":59},"obj":"SO:0000167"},{"id":"T2347","span":{"begin":84,"end":94},"obj":"GO:0010467"},{"id":"T2348","span":{"begin":200,"end":203},"obj":"PR:000003035"},{"id":"T2349","span":{"begin":224,"end":236},"obj":"GO:0009294"},{"id":"T2350","span":{"begin":390,"end":393},"obj":"PR:000003035"},{"id":"T2351","span":{"begin":394,"end":404},"obj":"GO:0065007"},{"id":"T2352","span":{"begin":449,"end":457},"obj":"CL:0002322"},{"id":"T2353","span":{"begin":477,"end":481},"obj":"NCBITaxon:10088"}],"text":" genomic setting and expressed from the endogenous promoter, ensuring physiological expression levels and correct spatio-temporal profiles. As significant differences between phenotypes from targeted p53 mutants in vivo and transfection data were observed [e.g. Refs (1–5)], more targeted mutations need to be generated and analyzed in multiple tissues to formulate more accurate models of p53 regulation.\nHowever, using homologous recombination in ES cells to generate mutant mice is an inefficient, slow and expensive method because (i) homologous recombination typically occurs at low fr"}

    2_test

    {"project":"2_test","denotations":[{"id":"16870721-12909629-76660890","span":{"begin":268,"end":269},"obj":"12909629"},{"id":"16870721-15456863-76660890","span":{"begin":268,"end":269},"obj":"15456863"},{"id":"16870721-14729946-76660890","span":{"begin":268,"end":269},"obj":"14729946"},{"id":"16870721-16006521-76660890","span":{"begin":268,"end":269},"obj":"16006521"},{"id":"16870721-16616333-76660890","span":{"begin":268,"end":269},"obj":"16616333"}],"text":" genomic setting and expressed from the endogenous promoter, ensuring physiological expression levels and correct spatio-temporal profiles. As significant differences between phenotypes from targeted p53 mutants in vivo and transfection data were observed [e.g. Refs (1–5)], more targeted mutations need to be generated and analyzed in multiple tissues to formulate more accurate models of p53 regulation.\nHowever, using homologous recombination in ES cells to generate mutant mice is an inefficient, slow and expensive method because (i) homologous recombination typically occurs at low fr"}