Id |
Subject |
Object |
Predicate |
Lexical cue |
T153 |
0-10 |
sentence |
denotes |
Background |
T154 |
0-10 |
NN |
denotes |
Background |
T155 |
10-193 |
sentence |
denotes |
One approach to resolving some of the in vivo functions of alpha-crystallin is to generate animal models where one or both of the alpha-crystallin gene products have been eliminated. |
T156 |
11-14 |
CD |
denotes |
One |
T157 |
15-23 |
NN |
denotes |
approach |
T158 |
87-89 |
VBZ |
denotes |
is |
T159 |
24-26 |
IN |
denotes |
to |
T160 |
27-36 |
VBG |
denotes |
resolving |
T161 |
37-41 |
DT |
denotes |
some |
T162 |
42-44 |
IN |
denotes |
of |
T163 |
45-48 |
DT |
denotes |
the |
T164 |
57-66 |
NNS |
denotes |
functions |
T165 |
49-51 |
FW |
denotes |
in |
T166 |
52-56 |
FW |
denotes |
vivo |
T167 |
67-69 |
IN |
denotes |
of |
T168 |
70-75 |
NN |
denotes |
alpha |
T169 |
76-86 |
NN |
denotes |
crystallin |
T170 |
75-76 |
HYPH |
denotes |
- |
T171 |
90-92 |
TO |
denotes |
to |
T172 |
93-101 |
VB |
denotes |
generate |
T173 |
102-108 |
NN |
denotes |
animal |
T174 |
109-115 |
NNS |
denotes |
models |
T175 |
116-121 |
WRB |
denotes |
where |
T176 |
182-192 |
VBN |
denotes |
eliminated |
T177 |
122-125 |
CD |
denotes |
one |
T178 |
126-128 |
CC |
denotes |
or |
T179 |
129-133 |
DT |
denotes |
both |
T180 |
134-136 |
IN |
denotes |
of |
T181 |
137-140 |
DT |
denotes |
the |
T182 |
163-171 |
NNS |
denotes |
products |
T183 |
141-146 |
NN |
denotes |
alpha |
T184 |
147-157 |
NN |
denotes |
crystallin |
T185 |
146-147 |
HYPH |
denotes |
- |
T186 |
158-162 |
NN |
denotes |
gene |
T187 |
172-176 |
VBP |
denotes |
have |
T188 |
177-181 |
VBN |
denotes |
been |
T189 |
192-193 |
. |
denotes |
. |
T190 |
193-446 |
sentence |
denotes |
In the single alpha-crystallin knockout mice, the remaining alpha-crystallin may fully or partially compensate for some of the functions of the missing protein, especially in the lens, where both alphaA and alphaB are normally expressed at high levels. |
T191 |
194-196 |
IN |
denotes |
In |
T192 |
294-304 |
VB |
denotes |
compensate |
T193 |
197-200 |
DT |
denotes |
the |
T194 |
234-238 |
NNS |
denotes |
mice |
T195 |
201-207 |
JJ |
denotes |
single |
T196 |
225-233 |
NN |
denotes |
knockout |
T197 |
208-213 |
NN |
denotes |
alpha |
T198 |
214-224 |
NN |
denotes |
crystallin |
T199 |
213-214 |
HYPH |
denotes |
- |
T200 |
238-240 |
, |
denotes |
, |
T201 |
240-243 |
DT |
denotes |
the |
T202 |
260-270 |
NN |
denotes |
crystallin |
T203 |
244-253 |
VBG |
denotes |
remaining |
T204 |
254-259 |
NN |
denotes |
alpha |
T205 |
259-260 |
HYPH |
denotes |
- |
T206 |
271-274 |
MD |
denotes |
may |
T207 |
275-280 |
RB |
denotes |
fully |
T208 |
281-283 |
CC |
denotes |
or |
T209 |
284-293 |
RB |
denotes |
partially |
T210 |
305-308 |
IN |
denotes |
for |
T211 |
309-313 |
DT |
denotes |
some |
T212 |
314-316 |
IN |
denotes |
of |
T213 |
317-320 |
DT |
denotes |
the |
T214 |
321-330 |
NNS |
denotes |
functions |
T215 |
331-333 |
IN |
denotes |
of |
T216 |
334-337 |
DT |
denotes |
the |
T217 |
346-353 |
NN |
denotes |
protein |
T218 |
338-345 |
VBG |
denotes |
missing |
T219 |
353-355 |
, |
denotes |
, |
T220 |
355-365 |
RB |
denotes |
especially |
T221 |
366-368 |
IN |
denotes |
in |
T222 |
369-372 |
DT |
denotes |
the |
T223 |
373-377 |
NN |
denotes |
lens |
T224 |
377-379 |
, |
denotes |
, |
T225 |
379-384 |
WRB |
denotes |
where |
T226 |
421-430 |
VBN |
denotes |
expressed |
T227 |
385-389 |
CC |
denotes |
both |
T228 |
390-396 |
NN |
denotes |
alphaA |
T229 |
397-400 |
CC |
denotes |
and |
T230 |
401-407 |
NN |
denotes |
alphaB |
T231 |
408-411 |
VBP |
denotes |
are |
T232 |
412-420 |
RB |
denotes |
normally |
T233 |
431-433 |
IN |
denotes |
at |
T234 |
434-438 |
JJ |
denotes |
high |
T235 |
439-445 |
NNS |
denotes |
levels |
T236 |
445-446 |
. |
denotes |
. |
T237 |
446-626 |
sentence |
denotes |
The purpose of this study was to characterize gross lenticular morphology in normal mice and mice with the targeted disruption of alphaA- and alphaB-crystallin genes (alphaA/BKO). |
T238 |
447-450 |
DT |
denotes |
The |
T239 |
451-458 |
NN |
denotes |
purpose |
T240 |
473-476 |
VBD |
denotes |
was |
T241 |
459-461 |
IN |
denotes |
of |
T242 |
462-466 |
DT |
denotes |
this |
T243 |
467-472 |
NN |
denotes |
study |
T244 |
477-479 |
TO |
denotes |
to |
T245 |
480-492 |
VB |
denotes |
characterize |
T246 |
493-498 |
JJ |
denotes |
gross |
T247 |
510-520 |
NN |
denotes |
morphology |
T248 |
499-509 |
JJ |
denotes |
lenticular |
T249 |
521-523 |
IN |
denotes |
in |
T250 |
524-530 |
JJ |
denotes |
normal |
T251 |
531-535 |
NNS |
denotes |
mice |
T252 |
536-539 |
CC |
denotes |
and |
T253 |
540-544 |
NNS |
denotes |
mice |
T254 |
545-549 |
IN |
denotes |
with |
T255 |
550-553 |
DT |
denotes |
the |
T256 |
563-573 |
NN |
denotes |
disruption |
T257 |
554-562 |
VBN |
denotes |
targeted |
T258 |
574-576 |
IN |
denotes |
of |
T259 |
577-583 |
NN |
denotes |
alphaA |
T260 |
596-606 |
NN |
denotes |
crystallin |
T261 |
583-584 |
HYPH |
denotes |
- |
T262 |
585-588 |
CC |
denotes |
and |
T263 |
589-595 |
NN |
denotes |
alphaB |
T264 |
595-596 |
HYPH |
denotes |
- |
T265 |
607-612 |
NNS |
denotes |
genes |
T266 |
613-614 |
-LRB- |
denotes |
( |
T267 |
614-620 |
NN |
denotes |
alphaA |
T268 |
621-624 |
NN |
denotes |
BKO |
T269 |
620-621 |
HYPH |
denotes |
/ |
T270 |
624-625 |
-RRB- |
denotes |
) |
T271 |
625-626 |
. |
denotes |
. |
T272 |
626-635 |
sentence |
denotes |
Methods |
T273 |
628-635 |
NNS |
denotes |
Methods |
T274 |
635-777 |
sentence |
denotes |
Lenses from 129SvEvTac mice and alphaA/BKO mice were examined by standard scanning electron microscopy and confocal microscopy methodologies. |
T275 |
636-642 |
NNS |
denotes |
Lenses |
T276 |
689-697 |
VBN |
denotes |
examined |
T277 |
643-647 |
IN |
denotes |
from |
T278 |
648-658 |
NN |
denotes |
129SvEvTac |
T279 |
659-663 |
NNS |
denotes |
mice |
T280 |
664-667 |
CC |
denotes |
and |
T281 |
668-674 |
NN |
denotes |
alphaA |
T282 |
675-678 |
NN |
denotes |
BKO |
T283 |
674-675 |
HYPH |
denotes |
/ |
T284 |
679-683 |
NNS |
denotes |
mice |
T285 |
684-688 |
VBD |
denotes |
were |
T286 |
698-700 |
IN |
denotes |
by |
T287 |
701-709 |
JJ |
denotes |
standard |
T288 |
728-738 |
NN |
denotes |
microscopy |
T289 |
710-718 |
NN |
denotes |
scanning |
T290 |
719-727 |
NN |
denotes |
electron |
T291 |
763-776 |
NNS |
denotes |
methodologies |
T292 |
739-742 |
CC |
denotes |
and |
T293 |
743-751 |
JJ |
denotes |
confocal |
T294 |
752-762 |
NN |
denotes |
microscopy |
T295 |
776-777 |
. |
denotes |
. |
T296 |
777-786 |
sentence |
denotes |
Results |
T297 |
779-786 |
NNS |
denotes |
Results |
T298 |
786-921 |
sentence |
denotes |
Equatorial and axial (sagittal) dimensions of lenses for alphaA/BKO mice were significantly smaller than age-matched wild type lenses. |
T299 |
787-797 |
JJ |
denotes |
Equatorial |
T300 |
819-829 |
NNS |
denotes |
dimensions |
T301 |
798-801 |
CC |
denotes |
and |
T302 |
802-807 |
JJ |
denotes |
axial |
T303 |
809-817 |
JJ |
denotes |
sagittal |
T304 |
808-809 |
-LRB- |
denotes |
( |
T305 |
817-818 |
-RRB- |
denotes |
) |
T306 |
860-864 |
VBD |
denotes |
were |
T307 |
830-832 |
IN |
denotes |
of |
T308 |
833-839 |
NNS |
denotes |
lenses |
T309 |
840-843 |
IN |
denotes |
for |
T310 |
844-850 |
NN |
denotes |
alphaA |
T311 |
851-854 |
NN |
denotes |
BKO |
T312 |
850-851 |
HYPH |
denotes |
/ |
T313 |
855-859 |
NNS |
denotes |
mice |
T314 |
865-878 |
RB |
denotes |
significantly |
T315 |
879-886 |
JJR |
denotes |
smaller |
T316 |
887-891 |
IN |
denotes |
than |
T317 |
892-895 |
NN |
denotes |
age |
T318 |
896-903 |
VBN |
denotes |
matched |
T319 |
895-896 |
HYPH |
denotes |
- |
T320 |
914-920 |
NNS |
denotes |
lenses |
T321 |
904-908 |
JJ |
denotes |
wild |
T322 |
909-913 |
NN |
denotes |
type |
T323 |
920-921 |
. |
denotes |
. |
T324 |
921-1037 |
sentence |
denotes |
No posterior sutures or fiber cells extending to the posterior capsule of the lens were found in alphaA/BKO lenses. |
T325 |
922-924 |
DT |
denotes |
No |
T326 |
935-942 |
NNS |
denotes |
sutures |
T327 |
925-934 |
JJ |
denotes |
posterior |
T328 |
1010-1015 |
VBN |
denotes |
found |
T329 |
943-945 |
CC |
denotes |
or |
T330 |
946-951 |
NN |
denotes |
fiber |
T331 |
952-957 |
NNS |
denotes |
cells |
T332 |
958-967 |
VBG |
denotes |
extending |
T333 |
968-970 |
IN |
denotes |
to |
T334 |
971-974 |
DT |
denotes |
the |
T335 |
985-992 |
NN |
denotes |
capsule |
T336 |
975-984 |
JJ |
denotes |
posterior |
T337 |
993-995 |
IN |
denotes |
of |
T338 |
996-999 |
DT |
denotes |
the |
T339 |
1000-1004 |
NN |
denotes |
lens |
T340 |
1005-1009 |
VBD |
denotes |
were |
T341 |
1016-1018 |
IN |
denotes |
in |
T342 |
1019-1025 |
NN |
denotes |
alphaA |
T343 |
1026-1029 |
NN |
denotes |
BKO |
T344 |
1025-1026 |
HYPH |
denotes |
/ |
T345 |
1030-1036 |
NNS |
denotes |
lenses |
T346 |
1036-1037 |
. |
denotes |
. |
T347 |
1037-1186 |
sentence |
denotes |
Ectopical nucleic acid staining was observed in the posterior subcapsular region of 5 wk and anterior subcapsular cortex of 54 wk alphaA/BKO lenses. |
T348 |
1038-1047 |
JJ |
denotes |
Ectopical |
T349 |
1061-1069 |
NN |
denotes |
staining |
T350 |
1048-1055 |
JJ |
denotes |
nucleic |
T351 |
1056-1060 |
NN |
denotes |
acid |
T352 |
1074-1082 |
VBN |
denotes |
observed |
T353 |
1070-1073 |
VBD |
denotes |
was |
T354 |
1083-1085 |
IN |
denotes |
in |
T355 |
1086-1089 |
DT |
denotes |
the |
T356 |
1112-1118 |
NN |
denotes |
region |
T357 |
1090-1099 |
JJ |
denotes |
posterior |
T358 |
1100-1111 |
JJ |
denotes |
subcapsular |
T359 |
1119-1121 |
IN |
denotes |
of |
T360 |
1122-1123 |
CD |
denotes |
5 |
T361 |
1124-1126 |
NN |
denotes |
wk |
T362 |
1127-1130 |
CC |
denotes |
and |
T363 |
1131-1139 |
JJ |
denotes |
anterior |
T364 |
1152-1158 |
NN |
denotes |
cortex |
T365 |
1140-1151 |
JJ |
denotes |
subcapsular |
T366 |
1179-1185 |
NNS |
denotes |
lenses |
T367 |
1159-1161 |
IN |
denotes |
of |
T368 |
1162-1164 |
CD |
denotes |
54 |
T369 |
1165-1167 |
NN |
denotes |
wk |
T370 |
1168-1174 |
NN |
denotes |
alphaA |
T371 |
1175-1178 |
NN |
denotes |
BKO |
T372 |
1174-1175 |
HYPH |
denotes |
/ |
T373 |
1185-1186 |
. |
denotes |
. |
T374 |
1186-1348 |
sentence |
denotes |
Gross morphological differences were also observed in the equatorial/bow, posterior and anterior regions of lenses from alphaA/BKO mice as compared to wild mice. |
T375 |
1187-1192 |
JJ |
denotes |
Gross |
T376 |
1207-1218 |
NNS |
denotes |
differences |
T377 |
1193-1206 |
JJ |
denotes |
morphological |
T378 |
1229-1237 |
VBN |
denotes |
observed |
T379 |
1219-1223 |
VBD |
denotes |
were |
T380 |
1224-1228 |
RB |
denotes |
also |
T381 |
1238-1240 |
IN |
denotes |
in |
T382 |
1241-1244 |
DT |
denotes |
the |
T383 |
1284-1291 |
NNS |
denotes |
regions |
T384 |
1245-1255 |
JJ |
denotes |
equatorial |
T385 |
1256-1259 |
JJ |
denotes |
bow |
T386 |
1255-1256 |
HYPH |
denotes |
/ |
T387 |
1259-1261 |
, |
denotes |
, |
T388 |
1261-1270 |
JJ |
denotes |
posterior |
T389 |
1271-1274 |
CC |
denotes |
and |
T390 |
1275-1283 |
JJ |
denotes |
anterior |
T391 |
1292-1294 |
IN |
denotes |
of |
T392 |
1295-1301 |
NNS |
denotes |
lenses |
T393 |
1302-1306 |
IN |
denotes |
from |
T394 |
1307-1313 |
NN |
denotes |
alphaA |
T395 |
1314-1317 |
NN |
denotes |
BKO |
T396 |
1313-1314 |
HYPH |
denotes |
/ |
T397 |
1318-1322 |
NNS |
denotes |
mice |
T398 |
1323-1325 |
IN |
denotes |
as |
T399 |
1326-1334 |
VBN |
denotes |
compared |
T400 |
1335-1337 |
IN |
denotes |
to |
T401 |
1338-1342 |
JJ |
denotes |
wild |
T402 |
1343-1347 |
NNS |
denotes |
mice |
T403 |
1347-1348 |
. |
denotes |
. |
T404 |
1348-1360 |
sentence |
denotes |
Conclusion |
T405 |
1350-1360 |
NN |
denotes |
Conclusion |
T406 |
1360-1544 |
sentence |
denotes |
These results indicated that both alphaA- and alphaB-crystallin are necessary for proper fiber cell formation, and that the absence of alpha-crystallin can lead to cataract formation. |
T407 |
1361-1366 |
DT |
denotes |
These |
T408 |
1367-1374 |
NNS |
denotes |
results |
T409 |
1375-1384 |
VBD |
denotes |
indicated |
T410 |
1385-1389 |
IN |
denotes |
that |
T411 |
1425-1428 |
VBP |
denotes |
are |
T412 |
1390-1394 |
CC |
denotes |
both |
T413 |
1395-1401 |
NN |
denotes |
alphaA |
T414 |
1414-1424 |
NN |
denotes |
crystallin |
T415 |
1401-1402 |
HYPH |
denotes |
- |
T416 |
1403-1406 |
CC |
denotes |
and |
T417 |
1407-1413 |
NN |
denotes |
alphaB |
T418 |
1413-1414 |
HYPH |
denotes |
- |
T419 |
1429-1438 |
JJ |
denotes |
necessary |
T420 |
1439-1442 |
IN |
denotes |
for |
T421 |
1443-1449 |
JJ |
denotes |
proper |
T422 |
1461-1470 |
NN |
denotes |
formation |
T423 |
1450-1455 |
NN |
denotes |
fiber |
T424 |
1456-1460 |
NN |
denotes |
cell |
T425 |
1470-1472 |
, |
denotes |
, |
T426 |
1472-1475 |
CC |
denotes |
and |
T427 |
1476-1480 |
IN |
denotes |
that |
T428 |
1517-1521 |
VB |
denotes |
lead |
T429 |
1481-1484 |
DT |
denotes |
the |
T430 |
1485-1492 |
NN |
denotes |
absence |
T431 |
1493-1495 |
IN |
denotes |
of |
T432 |
1496-1501 |
NN |
denotes |
alpha |
T433 |
1502-1512 |
NN |
denotes |
crystallin |
T434 |
1501-1502 |
HYPH |
denotes |
- |
T435 |
1513-1516 |
MD |
denotes |
can |
T436 |
1522-1524 |
IN |
denotes |
to |
T437 |
1525-1533 |
NN |
denotes |
cataract |
T438 |
1534-1543 |
NN |
denotes |
formation |
T439 |
1543-1544 |
. |
denotes |
. |
T3289 |
787-797 |
JJ |
denotes |
Equatorial |
T3290 |
819-829 |
NNS |
denotes |
dimensions |
T3291 |
798-801 |
CC |
denotes |
and |
T3292 |
802-807 |
JJ |
denotes |
axial |
T3293 |
809-817 |
JJ |
denotes |
sagittal |
T3294 |
808-809 |
-LRB- |
denotes |
( |
T3295 |
817-818 |
-RRB- |
denotes |
) |
T3297 |
830-832 |
IN |
denotes |
of |
T3298 |
833-839 |
NNS |
denotes |
lenses |
R41 |
T178 |
T177 |
cc |
or,one |
R42 |
T179 |
T177 |
conj |
both,one |
R43 |
T180 |
T177 |
prep |
of,one |
R44 |
T181 |
T182 |
det |
the,products |
R45 |
T182 |
T180 |
pobj |
products,of |
R20 |
T156 |
T157 |
nummod |
One,approach |
R21 |
T157 |
T158 |
nsubj |
approach,is |
R22 |
T159 |
T157 |
prep |
to,approach |
R23 |
T160 |
T159 |
pcomp |
resolving,to |
R24 |
T161 |
T160 |
dobj |
some,resolving |
R25 |
T162 |
T161 |
prep |
of,some |
R26 |
T163 |
T164 |
det |
the,functions |
R27 |
T164 |
T162 |
pobj |
functions,of |
R28 |
T165 |
T166 |
advmod |
in,vivo |
R29 |
T166 |
T164 |
amod |
vivo,functions |
R30 |
T167 |
T164 |
prep |
of,functions |
R31 |
T168 |
T169 |
compound |
alpha,crystallin |
R32 |
T169 |
T167 |
pobj |
crystallin,of |
R33 |
T170 |
T169 |
punct |
-,crystallin |
R34 |
T171 |
T172 |
aux |
to,generate |
R35 |
T172 |
T158 |
xcomp |
generate,is |
R36 |
T173 |
T174 |
compound |
animal,models |
R37 |
T174 |
T172 |
dobj |
models,generate |
R38 |
T175 |
T176 |
advmod |
where,eliminated |
R39 |
T176 |
T174 |
relcl |
eliminated,models |
R40 |
T177 |
T176 |
nsubjpass |
one,eliminated |
R46 |
T183 |
T184 |
compound |
alpha,crystallin |
R47 |
T184 |
T182 |
compound |
crystallin,products |
R48 |
T185 |
T184 |
punct |
-,crystallin |
R49 |
T186 |
T182 |
compound |
gene,products |
R50 |
T187 |
T176 |
aux |
have,eliminated |
R51 |
T188 |
T176 |
auxpass |
been,eliminated |
R52 |
T189 |
T158 |
punct |
.,is |
R53 |
T191 |
T192 |
prep |
In,compensate |
R54 |
T193 |
T194 |
det |
the,mice |
R55 |
T194 |
T191 |
pobj |
mice,In |
R56 |
T195 |
T196 |
amod |
single,knockout |
R57 |
T196 |
T194 |
compound |
knockout,mice |
R58 |
T197 |
T198 |
compound |
alpha,crystallin |
R59 |
T198 |
T196 |
compound |
crystallin,knockout |
R60 |
T199 |
T198 |
punct |
-,crystallin |
R61 |
T200 |
T192 |
punct |
", ",compensate |
R62 |
T201 |
T202 |
det |
the,crystallin |
R63 |
T202 |
T192 |
nsubj |
crystallin,compensate |
R64 |
T203 |
T202 |
amod |
remaining,crystallin |
R65 |
T204 |
T202 |
compound |
alpha,crystallin |
R66 |
T205 |
T202 |
punct |
-,crystallin |
R67 |
T206 |
T192 |
aux |
may,compensate |
R68 |
T207 |
T192 |
advmod |
fully,compensate |
R69 |
T208 |
T207 |
cc |
or,fully |
R70 |
T209 |
T207 |
conj |
partially,fully |
R71 |
T210 |
T192 |
prep |
for,compensate |
R72 |
T211 |
T210 |
pobj |
some,for |
R73 |
T212 |
T211 |
prep |
of,some |
R74 |
T213 |
T214 |
det |
the,functions |
R75 |
T214 |
T212 |
pobj |
functions,of |
R76 |
T215 |
T214 |
prep |
of,functions |
R77 |
T216 |
T217 |
det |
the,protein |
R78 |
T217 |
T215 |
pobj |
protein,of |
R79 |
T218 |
T217 |
amod |
missing,protein |
R80 |
T219 |
T192 |
punct |
", ",compensate |
R81 |
T220 |
T221 |
advmod |
especially,in |
R82 |
T221 |
T192 |
prep |
in,compensate |
R83 |
T222 |
T223 |
det |
the,lens |
R84 |
T223 |
T221 |
pobj |
lens,in |
R85 |
T224 |
T223 |
punct |
", ",lens |
R86 |
T225 |
T226 |
advmod |
where,expressed |
R88 |
T227 |
T228 |
preconj |
both,alphaA |
R89 |
T228 |
T226 |
nsubjpass |
alphaA,expressed |
R90 |
T229 |
T228 |
cc |
and,alphaA |
R91 |
T230 |
T228 |
conj |
alphaB,alphaA |
R92 |
T231 |
T226 |
auxpass |
are,expressed |
R93 |
T232 |
T226 |
advmod |
normally,expressed |
R94 |
T233 |
T226 |
prep |
at,expressed |
R95 |
T234 |
T235 |
amod |
high,levels |
R96 |
T235 |
T233 |
pobj |
levels,at |
R97 |
T236 |
T192 |
punct |
.,compensate |
R98 |
T238 |
T239 |
det |
The,purpose |
R99 |
T239 |
T240 |
nsubj |
purpose,was |
R100 |
T241 |
T239 |
prep |
of,purpose |
R101 |
T242 |
T243 |
det |
this,study |
R102 |
T243 |
T241 |
pobj |
study,of |
R103 |
T244 |
T245 |
aux |
to,characterize |
R104 |
T245 |
T240 |
xcomp |
characterize,was |
R105 |
T246 |
T247 |
amod |
gross,morphology |
R106 |
T247 |
T245 |
dobj |
morphology,characterize |
R107 |
T248 |
T247 |
amod |
lenticular,morphology |
R108 |
T249 |
T245 |
prep |
in,characterize |
R109 |
T250 |
T251 |
amod |
normal,mice |
R110 |
T251 |
T249 |
pobj |
mice,in |
R111 |
T252 |
T251 |
cc |
and,mice |
R112 |
T253 |
T251 |
conj |
mice,mice |
R113 |
T254 |
T253 |
prep |
with,mice |
R114 |
T255 |
T256 |
det |
the,disruption |
R115 |
T256 |
T254 |
pobj |
disruption,with |
R116 |
T257 |
T256 |
amod |
targeted,disruption |
R117 |
T258 |
T256 |
prep |
of,disruption |
R118 |
T259 |
T260 |
nmod |
alphaA,crystallin |
R119 |
T260 |
T265 |
compound |
crystallin,genes |
R120 |
T261 |
T259 |
punct |
-,alphaA |
R121 |
T262 |
T259 |
cc |
and,alphaA |
R122 |
T263 |
T259 |
conj |
alphaB,alphaA |
R123 |
T264 |
T260 |
punct |
-,crystallin |
R124 |
T265 |
T258 |
pobj |
genes,of |
R125 |
T266 |
T265 |
punct |
(,genes |
R126 |
T267 |
T268 |
compound |
alphaA,BKO |
R127 |
T268 |
T265 |
parataxis |
BKO,genes |
R128 |
T269 |
T268 |
punct |
/,BKO |
R129 |
T270 |
T268 |
punct |
),BKO |
R130 |
T271 |
T240 |
punct |
.,was |
R131 |
T275 |
T276 |
nsubjpass |
Lenses,examined |
R132 |
T277 |
T275 |
prep |
from,Lenses |
R133 |
T278 |
T279 |
compound |
129SvEvTac,mice |
R134 |
T279 |
T277 |
pobj |
mice,from |
R135 |
T280 |
T279 |
cc |
and,mice |
R136 |
T281 |
T282 |
compound |
alphaA,BKO |
R137 |
T282 |
T284 |
compound |
BKO,mice |
R138 |
T283 |
T282 |
punct |
/,BKO |
R139 |
T284 |
T279 |
conj |
mice,mice |
R140 |
T285 |
T276 |
auxpass |
were,examined |
R141 |
T286 |
T276 |
prep |
by,examined |
R142 |
T287 |
T288 |
amod |
standard,microscopy |
R143 |
T288 |
T291 |
nmod |
microscopy,methodologies |
R144 |
T289 |
T288 |
nmod |
scanning,microscopy |
R145 |
T290 |
T288 |
nmod |
electron,microscopy |
R146 |
T291 |
T286 |
pobj |
methodologies,by |
R147 |
T292 |
T288 |
cc |
and,microscopy |
R148 |
T293 |
T294 |
amod |
confocal,microscopy |
R149 |
T294 |
T288 |
conj |
microscopy,microscopy |
R150 |
T295 |
T276 |
punct |
.,examined |
R151 |
T299 |
T300 |
amod |
Equatorial,dimensions |
R152 |
T300 |
T306 |
nsubj |
dimensions,were |
R153 |
T301 |
T299 |
cc |
and,Equatorial |
R154 |
T302 |
T303 |
amod |
axial,sagittal |
R155 |
T303 |
T299 |
conj |
sagittal,Equatorial |
R156 |
T304 |
T303 |
punct |
(,sagittal |
R157 |
T305 |
T303 |
punct |
),sagittal |
R158 |
T307 |
T300 |
prep |
of,dimensions |
R159 |
T308 |
T307 |
pobj |
lenses,of |
R160 |
T309 |
T308 |
prep |
for,lenses |
R161 |
T310 |
T311 |
compound |
alphaA,BKO |
R162 |
T311 |
T313 |
compound |
BKO,mice |
R163 |
T312 |
T311 |
punct |
/,BKO |
R164 |
T313 |
T309 |
pobj |
mice,for |
R165 |
T314 |
T315 |
advmod |
significantly,smaller |
R166 |
T315 |
T306 |
acomp |
smaller,were |
R167 |
T316 |
T315 |
prep |
than,smaller |
R168 |
T317 |
T318 |
npadvmod |
age,matched |
R169 |
T318 |
T320 |
amod |
matched,lenses |
R170 |
T319 |
T318 |
punct |
-,matched |
R171 |
T320 |
T316 |
pobj |
lenses,than |
R172 |
T321 |
T322 |
amod |
wild,type |
R173 |
T322 |
T320 |
compound |
type,lenses |
R174 |
T323 |
T306 |
punct |
.,were |
R175 |
T325 |
T326 |
det |
No,sutures |
R176 |
T326 |
T328 |
nsubjpass |
sutures,found |
R177 |
T327 |
T326 |
amod |
posterior,sutures |
R178 |
T329 |
T326 |
cc |
or,sutures |
R179 |
T330 |
T331 |
compound |
fiber,cells |
R180 |
T331 |
T326 |
conj |
cells,sutures |
R181 |
T332 |
T326 |
acl |
extending,sutures |
R182 |
T333 |
T332 |
prep |
to,extending |
R183 |
T334 |
T335 |
det |
the,capsule |
R184 |
T335 |
T333 |
pobj |
capsule,to |
R185 |
T336 |
T335 |
amod |
posterior,capsule |
R186 |
T337 |
T335 |
prep |
of,capsule |
R187 |
T338 |
T339 |
det |
the,lens |
R188 |
T339 |
T337 |
pobj |
lens,of |
R189 |
T340 |
T328 |
auxpass |
were,found |
R190 |
T341 |
T328 |
prep |
in,found |
R191 |
T342 |
T343 |
compound |
alphaA,BKO |
R192 |
T343 |
T345 |
compound |
BKO,lenses |
R193 |
T344 |
T343 |
punct |
/,BKO |
R194 |
T345 |
T341 |
pobj |
lenses,in |
R195 |
T346 |
T328 |
punct |
.,found |
R196 |
T348 |
T349 |
amod |
Ectopical,staining |
R197 |
T349 |
T352 |
nsubjpass |
staining,observed |
R198 |
T350 |
T351 |
amod |
nucleic,acid |
R199 |
T351 |
T349 |
compound |
acid,staining |
R200 |
T353 |
T352 |
auxpass |
was,observed |
R201 |
T354 |
T352 |
prep |
in,observed |
R202 |
T355 |
T356 |
det |
the,region |
R203 |
T356 |
T354 |
pobj |
region,in |
R204 |
T357 |
T356 |
amod |
posterior,region |
R205 |
T358 |
T356 |
amod |
subcapsular,region |
R206 |
T359 |
T356 |
prep |
of,region |
R207 |
T360 |
T361 |
nummod |
5,wk |
R208 |
T361 |
T359 |
pobj |
wk,of |
R209 |
T362 |
T356 |
cc |
and,region |
R210 |
T363 |
T364 |
amod |
anterior,cortex |
R211 |
T364 |
T366 |
nmod |
cortex,lenses |
R212 |
T365 |
T364 |
amod |
subcapsular,cortex |
R214 |
T367 |
T364 |
prep |
of,cortex |
R215 |
T368 |
T369 |
nummod |
54,wk |
R216 |
T369 |
T367 |
pobj |
wk,of |
R217 |
T370 |
T371 |
compound |
alphaA,BKO |
R218 |
T371 |
T366 |
compound |
BKO,lenses |
R219 |
T372 |
T371 |
punct |
/,BKO |
R220 |
T373 |
T352 |
punct |
.,observed |
R221 |
T375 |
T376 |
amod |
Gross,differences |
R222 |
T376 |
T378 |
nsubjpass |
differences,observed |
R223 |
T377 |
T376 |
amod |
morphological,differences |
R224 |
T379 |
T378 |
auxpass |
were,observed |
R225 |
T380 |
T378 |
advmod |
also,observed |
R226 |
T381 |
T378 |
prep |
in,observed |
R227 |
T382 |
T383 |
det |
the,regions |
R228 |
T383 |
T381 |
pobj |
regions,in |
R229 |
T384 |
T385 |
amod |
equatorial,bow |
R230 |
T385 |
T383 |
amod |
bow,regions |
R231 |
T386 |
T385 |
punct |
/,bow |
R232 |
T387 |
T385 |
punct |
", ",bow |
R233 |
T388 |
T385 |
conj |
posterior,bow |
R234 |
T389 |
T388 |
cc |
and,posterior |
R235 |
T390 |
T388 |
conj |
anterior,posterior |
R236 |
T391 |
T383 |
prep |
of,regions |
R237 |
T392 |
T391 |
pobj |
lenses,of |
R238 |
T393 |
T392 |
prep |
from,lenses |
R239 |
T394 |
T395 |
compound |
alphaA,BKO |
R240 |
T395 |
T397 |
compound |
BKO,mice |
R241 |
T396 |
T395 |
punct |
/,BKO |
R242 |
T397 |
T393 |
pobj |
mice,from |
R243 |
T398 |
T399 |
mark |
as,compared |
R244 |
T399 |
T383 |
advcl |
compared,regions |
R245 |
T400 |
T399 |
prep |
to,compared |
R246 |
T401 |
T402 |
amod |
wild,mice |
R247 |
T402 |
T400 |
pobj |
mice,to |
R248 |
T403 |
T378 |
punct |
.,observed |
R249 |
T407 |
T408 |
det |
These,results |
R250 |
T408 |
T409 |
nsubj |
results,indicated |
R251 |
T410 |
T411 |
mark |
that,are |
R252 |
T411 |
T409 |
advcl |
are,indicated |
R253 |
T412 |
T413 |
preconj |
both,alphaA |
R254 |
T413 |
T414 |
nmod |
alphaA,crystallin |
R255 |
T414 |
T411 |
nsubj |
crystallin,are |
R256 |
T415 |
T413 |
punct |
-,alphaA |
R257 |
T416 |
T413 |
cc |
and,alphaA |
R258 |
T417 |
T413 |
conj |
alphaB,alphaA |
R259 |
T418 |
T414 |
punct |
-,crystallin |
R260 |
T419 |
T411 |
acomp |
necessary,are |
R261 |
T420 |
T419 |
prep |
for,necessary |
R262 |
T421 |
T422 |
amod |
proper,formation |
R263 |
T422 |
T420 |
pobj |
formation,for |
R264 |
T423 |
T424 |
compound |
fiber,cell |
R265 |
T424 |
T422 |
compound |
cell,formation |
R266 |
T425 |
T411 |
punct |
", ",are |
R267 |
T426 |
T411 |
cc |
and,are |
R268 |
T427 |
T428 |
mark |
that,lead |
R269 |
T428 |
T411 |
conj |
lead,are |
R270 |
T429 |
T430 |
det |
the,absence |
R271 |
T430 |
T428 |
nsubj |
absence,lead |
R272 |
T431 |
T430 |
prep |
of,absence |
R273 |
T432 |
T433 |
compound |
alpha,crystallin |
R274 |
T433 |
T431 |
pobj |
crystallin,of |
R275 |
T434 |
T433 |
punct |
-,crystallin |
R276 |
T435 |
T428 |
aux |
can,lead |
R277 |
T436 |
T428 |
prep |
to,lead |
R278 |
T437 |
T438 |
compound |
cataract,formation |
R279 |
T438 |
T436 |
pobj |
formation,to |
R280 |
T439 |
T409 |
punct |
.,indicated |
R1977 |
T3289 |
T3290 |
amod |
Equatorial,dimensions |
R1979 |
T3291 |
T3289 |
cc |
and,Equatorial |
R1980 |
T3292 |
T3293 |
amod |
axial,sagittal |
R1981 |
T3293 |
T3289 |
conj |
sagittal,Equatorial |
R1982 |
T3294 |
T3293 |
punct |
(,sagittal |
R1983 |
T3295 |
T3290 |
punct |
),dimensions |
R1984 |
T3297 |
T3290 |
prep |
of,dimensions |
R1985 |
T3298 |
T3297 |
pobj |
lenses,of |
R87 |
T226 |
T223 |
relcl |
expressed,lens |
R213 |
T366 |
T356 |
conj |
lenses,region |