PMC:1482699 / 50117-52252 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1482699","sourcedb":"PMC","sourceid":"1482699","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1482699","text":"Table 1 B6.CAST and HG.CAST speed congenic strains developed to isolate and characterize genome-wide QTL affecting growth and obesity\nQTLa MMU Peak LOD cM (Mbp)b Full congenic named Abbreviation Min. interval (Mbp)e\nWg1 2 31 (52) B6.CAST-(D2Mit1-D2Mit160)N(6) B62P 3.8–84.8\nHG.CAST-(D2Mit1-D2Mit160)N(6) HG2P 3.8–84.8\nB6.CAST-(D2Mit322-D2Mit439)N(6) B62PM 42.9–92.0\nHG.CAST-(D2Mit322-D2Mit439)N(6) HG2PM 42.9–92.0\nWg2 2 59–83c B6.CAST-(D2Mit329-D2Mit490)N(6) B62M 74.9–138.6\nCarp1 (115–150) HG.CAST-(D2Mit329-D2Mit490)N(6) HG2M 74.9–138.6\nCara1 B6.CAST-(D2Mit329-D2Mit457)N(6) B62D 74.9–181.8\nFeml1 HG.CAST-(D2Mit329-D2Mit457)N(6) HG2D 74.9–181.8\nQ1Ucd1 -w26 1 16 (35) HG.CAST-(D1Mit118-D1Mit250)N(6) HG1 4.0–70.6\nCarfhg1 5 38 (100) HG.CAST-(D5Mit229-D5Mit158)N(6) HG5 30.7–114.2\nWg3 8 45 (98) HG.CAST-(D8Mit9-D8Mit198)N(6) HG8 70.2–104.1\nCarfhg2 9 10 (30) HG.CAST-(D9Mit249-D9Mit133)N(6) HG9 9.1–84.2\nFeml2 9 20 (48) HG.CAST-(D9Mit249-D9Mit133)N(6) HG9 9.1–84.2\nCarp2 Wg4 Cara2 11 46–50 (80–90) HG.CAST-(D11Mit260-D11Mit255)N(6) HG11 61.9–114.3\nFeml3 Carp3 Cara3 17 46–48 (70–76) HG.CAST-(D17Mit213-D17Mit142)N(6) HG17 14.8–77.3\nQTL, quantitative trait locus; MMU, mouse chromosome; LOD, log of the odds\na QTL MGI [59] nomenclature. Q1Ucd1-w26 never received an official MGI name, because it only reached a suggestive level of significance; hg modifier QTL are in bold [24].\nb Mbp position according to the August 2005 mm7 UCSC [28] genome assembly (NCBI Build 35), peak LOD from [24].\nc In the linkage analysis performed in [24], the peak location for Wg2, Carp1, Cara1 and Feml1 was 59–63 cM (115–120 Mbp) in hg/hg F2 mice and 78–83 cM (135–150 Mbp) in +/+ F2 mice.\nd Full congenic name consists of three parts: 1. B6.CAST, indicates the recipient strain is B6 and the donor strain is CAST; HG.CAST, indicates the recipient strain is HG and the donor strain is CAST; 2. markers defining the minimal congenic interval; 3. the number of backcrosses used for speed congenic development.\ne Represents the minimum genomic region spanned by CAST donor 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