Table 1  B6.CAST and HG.CAST speed congenic strains developed to isolate and characterize genome-wide QTL affecting growth and obesity
QTLa  MMU  Peak LOD cM (Mbp)b  Full congenic named  Abbreviation  Min. interval (Mbp)e
Wg1  2  31 (52)  B6.CAST-(D2Mit1-D2Mit160)N(6)  B62P  3.8–84.8
HG.CAST-(D2Mit1-D2Mit160)N(6)  HG2P  3.8–84.8
B6.CAST-(D2Mit322-D2Mit439)N(6)  B62PM  42.9–92.0
HG.CAST-(D2Mit322-D2Mit439)N(6)  HG2PM  42.9–92.0
Wg2  2  59–83c  B6.CAST-(D2Mit329-D2Mit490)N(6)  B62M  74.9–138.6
Carp1   (115–150)  HG.CAST-(D2Mit329-D2Mit490)N(6)  HG2M  74.9–138.6
Cara1    B6.CAST-(D2Mit329-D2Mit457)N(6)  B62D  74.9–181.8
Feml1    HG.CAST-(D2Mit329-D2Mit457)N(6)  HG2D  74.9–181.8
Q1Ucd1 -w26  1  16 (35)  HG.CAST-(D1Mit118-D1Mit250)N(6)  HG1  4.0–70.6
Carfhg1  5  38 (100)  HG.CAST-(D5Mit229-D5Mit158)N(6)  HG5  30.7–114.2
Wg3  8  45 (98)  HG.CAST-(D8Mit9-D8Mit198)N(6)  HG8  70.2–104.1
Carfhg2  9  10 (30)  HG.CAST-(D9Mit249-D9Mit133)N(6)  HG9  9.1–84.2
Feml2  9  20 (48)  HG.CAST-(D9Mit249-D9Mit133)N(6)  HG9  9.1–84.2
Carp2   Wg4  Cara2  11  46–50 (80–90)  HG.CAST-(D11Mit260-D11Mit255)N(6)  HG11  61.9–114.3
Feml3   Carp3  Cara3  17  46–48 (70–76)  HG.CAST-(D17Mit213-D17Mit142)N(6)  HG17  14.8–77.3
QTL, quantitative trait locus; MMU, mouse chromosome; LOD, log of the odds
a QTL MGI [59] nomenclature. Q1Ucd1-w26 never received an official MGI name, because it only reached a suggestive level of significance; hg modifier QTL are in bold [24].
b Mbp position according to the August 2005 mm7 UCSC [28] genome assembly (NCBI Build 35), peak LOD from [24].
c In the linkage analysis performed in [24], the peak location for Wg2, Carp1, Cara1 and Feml1 was 59–63 cM (115–120 Mbp) in hg/hg F2 mice and 78–83 cM (135–150 Mbp) in +/+ F2 mice.
d Full congenic name consists of three parts: 1. B6.CAST, indicates the recipient strain is B6 and the donor strain is CAST; HG.CAST, indicates the recipient strain is HG and the donor strain is CAST; 2. markers defining the minimal congenic interval; 3. the number of backcrosses used for speed congenic development.
e Represents the minimum genomic region spanned by CAST donor alleles.