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PMC:1482699 / 3962-4932 JSONTXT

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Id Subject Object Predicate Lexical cue
T3152 0-3 NN denotes QTL
T3153 60-68 VBN denotes referred
T3154 4-9 WDT denotes which
T3155 10-15 VBP denotes alter
T3156 16-19 DT denotes the
T3157 31-38 NNS denotes effects
T3158 20-30 JJ denotes phenotypic
T3159 39-41 IN denotes of
T3160 42-49 DT denotes another
T3161 50-55 NN denotes locus
T3162 56-59 VBP denotes are
T3163 69-71 IN denotes to
T3164 72-74 IN denotes as
T3165 75-83 NN denotes modifier
T3166 84-87 NN denotes QTL
T3167 88-89 -LRB- denotes [
T3168 89-91 CD denotes 18
T3169 91-92 -RRB- denotes ]
T3170 92-93 . denotes .
T3171 93-320 sentence denotes Modifier QTL have been mapped for numerous traits and in these studies the modified locus is typically a known gene containing a spontaneously arisen or engineered mutation with major phenotypic effects, such as hg [11,19-21].
T3172 94-102 NN denotes Modifier
T3173 103-106 NN denotes QTL
T3174 117-123 VBN denotes mapped
T3175 107-111 VBP denotes have
T3176 112-116 VBN denotes been
T3177 124-127 IN denotes for
T3178 128-136 JJ denotes numerous
T3179 137-143 NNS denotes traits
T3180 144-147 CC denotes and
T3181 148-150 IN denotes in
T3182 184-186 VBZ denotes is
T3183 151-156 DT denotes these
T3184 157-164 NNS denotes studies
T3185 165-168 DT denotes the
T3186 178-183 NN denotes locus
T3187 169-177 VBN denotes modified
T3188 187-196 RB denotes typically
T3189 197-198 DT denotes a
T3190 205-209 NN denotes gene
T3191 199-204 VBN denotes known
T3192 210-220 VBG denotes containing
T3193 221-222 DT denotes a
T3194 258-266 NN denotes mutation
T3195 223-236 RB denotes spontaneously
T3196 237-243 VBN denotes arisen
T3197 244-246 CC denotes or
T3198 247-257 VBN denotes engineered
T3199 267-271 IN denotes with
T3200 272-277 JJ denotes major
T3201 289-296 NNS denotes effects
T3202 278-288 JJ denotes phenotypic
T3203 296-298 , denotes ,
T3204 298-302 JJ denotes such
T3205 303-305 IN denotes as
T3206 306-308 NN denotes hg
T3207 309-310 -LRB- denotes [
T3208 310-312 CD denotes 11
T3209 312-313 , denotes ,
T3210 313-315 CD denotes 19
T3211 315-316 SYM denotes -
T3212 316-318 CD denotes 21
T3213 318-319 -RRB- denotes ]
T3214 319-320 . denotes .
T3215 320-474 sentence denotes Epistasis forms the basis of these interactions, implying that the known gene and its modifiers are members of the same biochemical or metabolic pathway.
T3216 321-330 NN denotes Epistasis
T3217 331-336 VBZ denotes forms
T3218 337-340 DT denotes the
T3219 341-346 NN denotes basis
T3220 347-349 IN denotes of
T3221 350-355 DT denotes these
T3222 356-368 NNS denotes interactions
T3223 368-370 , denotes ,
T3224 370-378 VBG denotes implying
T3225 379-383 IN denotes that
T3226 417-420 VBP denotes are
T3227 384-387 DT denotes the
T3228 394-398 NN denotes gene
T3229 388-393 VBN denotes known
T3230 399-402 CC denotes and
T3231 403-406 PRP$ denotes its
T3232 407-416 NNS denotes modifiers
T3233 421-428 NNS denotes members
T3234 429-431 IN denotes of
T3235 432-435 DT denotes the
T3236 466-473 NN denotes pathway
T3237 436-440 JJ denotes same
T3238 441-452 JJ denotes biochemical
T3239 453-455 CC denotes or
T3240 456-465 JJ denotes metabolic
T3241 473-474 . denotes .
T3242 474-574 sentence denotes Different genetic backgrounds have been shown to modify the growth-enhancing effects of hg [15,22].
T3243 475-484 JJ denotes Different
T3244 493-504 NNS denotes backgrounds
T3245 485-492 JJ denotes genetic
T3246 515-520 VBN denotes shown
T3247 505-509 VBP denotes have
T3248 510-514 VBN denotes been
T3249 521-523 TO denotes to
T3250 524-530 VB denotes modify
T3251 531-534 DT denotes the
T3252 552-559 NNS denotes effects
T3253 535-541 NN denotes growth
T3254 542-551 VBG denotes enhancing
T3255 541-542 HYPH denotes -
T3256 560-562 IN denotes of
T3257 563-565 NN denotes hg
T3258 566-567 -LRB- denotes [
T3259 570-572 CD denotes 22
T3260 567-569 CD denotes 15
T3261 569-570 , denotes ,
T3262 572-573 -RRB- denotes ]
T3263 573-574 . denotes .
T3264 574-801 sentence denotes Since the primary function of Socs2 is to negatively regulate growth hormone (Gh) [23], it is likely these background effects are the result of polymorphism influencing interactions between members of the Gh signaling pathway.
T3265 575-580 IN denotes Since
T3266 611-613 VBZ denotes is
T3267 581-584 DT denotes the
T3268 593-601 NN denotes function
T3269 585-592 JJ denotes primary
T3270 602-604 IN denotes of
T3271 605-610 NN denotes Socs2
T3272 666-668 VBZ denotes is
T3273 614-616 TO denotes to
T3274 628-636 VB denotes regulate
T3275 617-627 RB denotes negatively
T3276 637-643 NN denotes growth
T3277 644-651 NN denotes hormone
T3278 652-653 -LRB- denotes (
T3279 653-655 NN denotes Gh
T3280 655-656 -RRB- denotes )
T3281 657-658 -LRB- denotes [
T3282 658-660 CD denotes 23
T3283 660-661 -RRB- denotes ]
T3284 661-663 , denotes ,
T3285 663-665 PRP denotes it
T3286 669-675 JJ denotes likely
T3287 676-681 DT denotes these
T3288 693-700 NNS denotes effects
T3289 682-692 NN denotes background
T3290 701-704 VBP denotes are
T3291 705-708 DT denotes the
T3292 709-715 NN denotes result
T3293 716-718 IN denotes of
T3294 719-731 NN denotes polymorphism
T3295 732-743 VBG denotes influencing
T3296 744-756 NNS denotes interactions
T3297 757-764 IN denotes between
T3298 765-772 NNS denotes members
T3299 773-775 IN denotes of
T3300 776-779 DT denotes the
T3301 793-800 NN denotes pathway
T3302 780-782 NN denotes Gh
T3303 783-792 NN denotes signaling
T3304 800-801 . denotes .
T3305 801-970 sentence denotes Thus, identification of hg modifiers has the potential to uncover novel members of metabolically important pathways or previously unknown convergences between pathways.
T3306 802-806 RB denotes Thus
T3307 839-842 VBZ denotes has
T3308 806-808 , denotes ,
T3309 808-822 NN denotes identification
T3310 823-825 IN denotes of
T3311 826-828 NN denotes hg
T3312 829-838 NNS denotes modifiers
T3313 843-846 DT denotes the
T3314 847-856 NN denotes potential
T3315 857-859 TO denotes to
T3316 860-867 VB denotes uncover
T3317 868-873 JJ denotes novel
T3318 874-881 NNS denotes members
T3319 882-884 IN denotes of
T3320 885-898 RB denotes metabolically
T3321 899-908 JJ denotes important
T3322 909-917 NNS denotes pathways
T3323 918-920 CC denotes or
T3324 921-931 RB denotes previously
T3325 932-939 JJ denotes unknown
T3326 940-952 NNS denotes convergences
T3327 953-960 IN denotes between
T3328 961-969 NNS denotes pathways
T3329 969-970 . denotes .
R674 T3220 T3219 prep of,basis
R675 T3221 T3222 det these,interactions
R677 T3222 T3220 pobj interactions,of
R678 T3223 T3217 punct ", ",forms
R679 T3224 T3217 advcl implying,forms
R681 T3225 T3226 mark that,are
R682 T3226 T3224 ccomp are,implying
R684 T3227 T3228 det the,gene
R685 T3228 T3226 nsubj gene,are
R686 T3229 T3228 amod known,gene
R687 T3230 T3228 cc and,gene
R689 T3231 T3232 poss its,modifiers
R690 T3232 T3228 conj modifiers,gene
R692 T3233 T3226 attr members,are
R693 T3234 T3233 prep of,members
R695 T3235 T3236 det the,pathway
R696 T3236 T3234 pobj pathway,of
R697 T3237 T3236 amod same,pathway
R698 T3238 T3236 amod biochemical,pathway
R699 T3239 T3238 cc or,biochemical
R700 T3240 T3238 conj metabolic,biochemical
R701 T3241 T3217 punct .,forms
R703 T3243 T3244 amod Different,backgrounds
R704 T3244 T3246 nsubjpass backgrounds,shown
R705 T3245 T3244 amod genetic,backgrounds
R707 T3247 T3246 aux have,shown
R708 T3248 T3246 auxpass been,shown
R710 T3249 T3250 aux to,modify
R712 T3250 T3246 xcomp modify,shown
R713 T3251 T3252 det the,effects
R714 T3252 T3250 dobj effects,modify
R716 T3253 T3254 npadvmod growth,enhancing
R717 T3254 T3252 amod enhancing,effects
R718 T3255 T3254 punct -,enhancing
R720 T3256 T3252 prep of,effects
R721 T3257 T3256 pobj hg,of
R722 T3258 T3259 punct [,22
R723 T3259 T3246 parataxis 22,shown
R724 T3152 T3153 nsubjpass QTL,referred
R725 T3260 T3259 nummod 15,22
R726 T3261 T3259 punct ",",22
R727 T3262 T3259 punct ],22
R728 T3154 T3155 dep which,alter
R729 T3263 T3246 punct .,shown
R730 T3265 T3266 mark Since,is
R731 T3266 T3272 advcl is,is
R732 T3267 T3268 det the,function
R733 T3155 T3152 relcl alter,QTL
R734 T3268 T3266 nsubj function,is
R735 T3269 T3268 amod primary,function
R736 T3270 T3268 prep of,function
R737 T3156 T3157 det the,effects
R738 T3271 T3270 pobj Socs2,of
R739 T3157 T3155 dobj effects,alter
R740 T3273 T3274 aux to,regulate
R741 T3274 T3266 xcomp regulate,is
R742 T3275 T3274 advmod negatively,regulate
R743 T3276 T3277 compound growth,hormone
R744 T3158 T3157 amod phenotypic,effects
R745 T3277 T3274 dobj hormone,regulate
R746 T3278 T3277 punct (,hormone
R747 T3159 T3157 prep of,effects
R748 T3279 T3277 appos Gh,hormone
R749 T3280 T3266 punct ),is
R750 T3281 T3282 punct [,23
R751 T3282 T3266 parataxis 23,is
R752 T3160 T3161 det another,locus
R753 T3283 T3282 punct ],23
R754 T3284 T3272 punct ", ",is
R755 T3285 T3272 nsubj it,is
R756 T3161 T3159 pobj locus,of
R757 T3286 T3272 acomp likely,is
R758 T3287 T3288 det these,effects
R759 T3162 T3153 auxpass are,referred
R760 T3288 T3290 nsubj effects,are
R761 T3289 T3288 compound background,effects
R762 T3163 T3153 prep to,referred
R763 T3290 T3286 advcl are,likely
R764 T3291 T3292 det the,result
R765 T3164 T3153 prep as,referred
R766 T3292 T3290 attr result,are
R767 T3293 T3292 prep of,result
R768 T3294 T3295 nsubj polymorphism,influencing
R769 T3295 T3293 pcomp influencing,of
R770 T3165 T3166 compound modifier,QTL
R771 T3296 T3295 dobj interactions,influencing
R772 T3297 T3296 prep between,interactions
R773 T3298 T3297 pobj members,between
R774 T3166 T3164 pobj QTL,as
R775 T3299 T3298 prep of,members
R776 T3300 T3301 det the,pathway
R777 T3301 T3299 pobj pathway,of
R778 T3167 T3168 punct [,18
R779 T3302 T3303 compound Gh,signaling
R780 T3303 T3301 compound signaling,pathway
R781 T3304 T3272 punct .,is
R782 T3168 T3153 parataxis 18,referred
R783 T3306 T3307 advmod Thus,has
R784 T3169 T3168 punct ],18
R785 T3308 T3307 punct ", ",has
R786 T3309 T3307 nsubj identification,has
R787 T3170 T3153 punct .,referred
R788 T3310 T3309 prep of,identification
R789 T3311 T3312 compound hg,modifiers
R790 T3312 T3310 pobj modifiers,of
R791 T3172 T3173 compound Modifier,QTL
R792 T3313 T3314 det the,potential
R793 T3314 T3307 dobj potential,has
R794 T3315 T3316 aux to,uncover
R795 T3316 T3314 acl uncover,potential
R796 T3173 T3174 nsubjpass QTL,mapped
R797 T3317 T3318 amod novel,members
R798 T3318 T3316 dobj members,uncover
R799 T3319 T3318 prep of,members
R800 T3320 T3321 advmod metabolically,important
R801 T3321 T3322 amod important,pathways
R802 T3322 T3319 pobj pathways,of
R803 T3175 T3174 aux have,mapped
R804 T3323 T3318 cc or,members
R805 T3324 T3325 advmod previously,unknown
R806 T3325 T3326 amod unknown,convergences
R807 T3176 T3174 auxpass been,mapped
R808 T3177 T3174 prep for,mapped
R809 T3326 T3318 conj convergences,members
R810 T3178 T3179 amod numerous,traits
R811 T3327 T3326 prep between,convergences
R812 T3328 T3327 pobj pathways,between
R813 T3329 T3307 punct .,has
R814 T3179 T3177 pobj traits,for
R816 T3180 T3174 cc and,mapped
R819 T3181 T3182 prep in,is
R823 T3182 T3174 conj is,mapped
R827 T3183 T3184 det these,studies
R831 T3184 T3181 pobj studies,in
R835 T3185 T3186 det the,locus
R839 T3186 T3182 nsubj locus,is
R843 T3187 T3186 amod modified,locus
R847 T3188 T3182 advmod typically,is
R851 T3189 T3190 det a,gene
R856 T3190 T3182 attr gene,is
R859 T3191 T3190 amod known,gene
R861 T3192 T3190 acl containing,gene
R864 T3193 T3194 det a,mutation
R868 T3194 T3192 dobj mutation,containing
R872 T3195 T3196 advmod spontaneously,arisen
R874 T3196 T3194 amod arisen,mutation
R879 T3197 T3196 cc or,arisen
R883 T3198 T3196 conj engineered,arisen
R886 T3199 T3194 prep with,mutation
R891 T3200 T3201 amod major,effects
R895 T3201 T3199 pobj effects,with
R898 T3202 T3201 amod phenotypic,effects
R903 T3203 T3194 punct ", ",mutation
R910 T3204 T3205 amod such,as
R915 T3205 T3194 prep as,mutation
R919 T3206 T3205 pobj hg,as
R923 T3207 T3208 punct [,11
R925 T3208 T3182 parataxis 11,is
R930 T3209 T3208 punct ",",11
R933 T3210 T3208 appos 19,11
R937 T3211 T3212 punct -,21
R941 T3212 T3210 prep 21,19
R943 T3213 T3208 punct ],11
R944 T3214 T3182 punct .,is
R946 T3216 T3217 nsubj Epistasis,forms
R951 T3218 T3219 det the,basis
R955 T3219 T3217 dobj basis,forms

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T2670 0-3 SO_EXT:0000771 denotes QTL
T2671 84-87 SO_EXT:0000771 denotes QTL
T2672 103-106 SO_EXT:0000771 denotes QTL
T2673 169-177 SO_EXT:sequence_alteration_process denotes modified
T2674 205-209 SO_EXT:0000704 denotes gene
T2675 258-266 SO_EXT:sequence_alteration_entity_or_process denotes mutation
T2676 394-398 SO_EXT:0000704 denotes gene
T2677 441-452 CHEBI_EXT:biochemical denotes biochemical
T2678 456-465 GO:0008152 denotes metabolic
T2679 485-492 SO_EXT:0000704 denotes genetic
T2680 535-541 GO_EXT:biological_growth_entity_or_process denotes growth
T2681 605-610 PR_EXT:000015393 denotes Socs2
T2682 617-636 GO_EXT:negative_regulation denotes negatively regulate
T2683 637-643 GO_EXT:biological_growth_entity_or_process denotes growth
T2684 637-651 CHEBI_GO_PR_EXT:growth_hormone denotes growth hormone
T2685 653-655 CHEBI_GO_PR_EXT:growth_hormone denotes Gh
T2686 719-731 SO_EXT:polymorphism denotes polymorphism
T2687 780-782 CHEBI_GO_PR_EXT:growth_hormone denotes Gh
T2688 780-800 GO:0060396 denotes Gh signaling pathway
T2689 885-898 GO:0008152 denotes metabolically

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T2591 0-3 SO:0000771 denotes QTL
T2592 84-87 SO:0000771 denotes QTL
T2593 103-106 SO:0000771 denotes QTL
T2594 205-209 SO:0000704 denotes gene
T2595 394-398 SO:0000704 denotes gene
T2596 456-465 GO:0008152 denotes metabolic
T2597 485-492 SO:0000704 denotes genetic
T2598 605-610 PR:000015393 denotes Socs2
T2599 780-800 GO:0060396 denotes Gh signaling pathway
T2600 885-898 GO:0008152 denotes metabolically