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confirmation of Carfhg2 all measures of adiposity in HG9 mice were increased relative to control mice; except MFP in both sexes and BMI in males (Table 5). In males, GFP, RFP, FFP and AI were increased by 29.0%, 51.2%, 42.9% and 30.0%, respectively. In females these increases were much larger. The same measurements were increased by 68.8%, 99.4%, 69.7% and 57.3%, relative to HGC females. A 2.9% and 3.6% reduction in male and female NA, respectively, was also detected. This was expected since NA was previously found to be an excellent indicator of femur length (R2 = 0.88) in HG mice [27] and as noted above this region contains the Feml2 QTL [24]. These data confirm the effects of Carfhg2 on adiposity and Feml2 on length and indicate the isolated effects of Carfhg2 are more significant than originally observed."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T10988","span":{"begin":60,"end":64},"obj":"NCBITaxon:10088"},{"id":"T10989","span":{"begin":100,"end":104},"obj":"NCBITaxon:10088"},{"id":"T10990","span":{"begin":113,"end":116},"obj":"UBERON:0015143"},{"id":"T10991","span":{"begin":142,"end":147},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T10992","span":{"begin":162,"end":167},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T10993","span":{"begin":169,"end":172},"obj":"UBERON:0003428"},{"id":"T10994","span":{"begin":174,"end":177},"obj":"UBERON:0010411"},{"id":"T10995","span":{"begin":179,"end":182},"obj":"UBERON:0012283"},{"id":"T10996","span":{"begin":256,"end":263},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T10997","span":{"begin":385,"end":392},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T10998","span":{"begin":423,"end":427},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T10999","span":{"begin":432,"end":438},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T11000","span":{"begin":556,"end":561},"obj":"UBERON:0000981"},{"id":"T11001","span":{"begin":587,"end":591},"obj":"NCBITaxon:10088"},{"id":"T11002","span":{"begin":647,"end":650},"obj":"SO_EXT:0000771"}],"text":"In confirmation of Carfhg2 all measures of adiposity in HG9 mice were increased relative to control mice; except MFP in both sexes and BMI in males (Table 5). In males, GFP, RFP, FFP and AI were increased by 29.0%, 51.2%, 42.9% and 30.0%, respectively. In females these increases were much larger. The same measurements were increased by 68.8%, 99.4%, 69.7% and 57.3%, relative to HGC females. A 2.9% and 3.6% reduction in male and female NA, respectively, was also detected. This was expected since NA was previously found to be an excellent indicator of femur length (R2 = 0.88) in HG mice [27] and as noted above this region contains the Feml2 QTL [24]. These data confirm the effects of Carfhg2 on adiposity and Feml2 on length and indicate the isolated effects of Carfhg2 are more significant than originally observed."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T10901","span":{"begin":60,"end":64},"obj":"NCBITaxon:10088"},{"id":"T10902","span":{"begin":100,"end":104},"obj":"NCBITaxon:10088"},{"id":"T10903","span":{"begin":113,"end":116},"obj":"UBERON:0015143"},{"id":"T10904","span":{"begin":169,"end":172},"obj":"UBERON:0003428"},{"id":"T10905","span":{"begin":174,"end":177},"obj":"UBERON:0010411"},{"id":"T10906","span":{"begin":179,"end":182},"obj":"UBERON:0012283"},{"id":"T10907","span":{"begin":556,"end":561},"obj":"UBERON:0000981"},{"id":"T10908","span":{"begin":587,"end":591},"obj":"NCBITaxon:10088"},{"id":"T10909","span":{"begin":647,"end":650},"obj":"SO:0000771"}],"text":"In confirmation of Carfhg2 all measures of adiposity in HG9 mice were increased relative to control mice; except MFP in both sexes and BMI in males (Table 5). In males, GFP, RFP, FFP and AI were increased by 29.0%, 51.2%, 42.9% and 30.0%, respectively. In females these increases were much larger. The same measurements were increased by 68.8%, 99.4%, 69.7% and 57.3%, relative to HGC females. A 2.9% and 3.6% reduction in male and female NA, respectively, was also detected. This was expected since NA was previously found to be an excellent indicator of femur length (R2 = 0.88) in HG mice [27] and as noted above this region contains the Feml2 QTL [24]. These data confirm the effects of Carfhg2 on adiposity and Feml2 on length and indicate the isolated effects of Carfhg2 are more significant than originally observed."}