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PMC:1448208 / 521-964 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T926 0-7 NNS denotes Methods
T927 7-216 sentence denotes To create a murine model of classic MSUD, we used gene targeting and embryonic stem cell technologies to create a mouse line that lacked a functional E2 subunit gene of branched-chain keto acid dehydrogenase.
T928 8-10 TO denotes To
T929 11-17 VB denotes create
T930 53-57 VBD denotes used
T931 18-19 DT denotes a
T932 27-32 NN denotes model
T933 20-26 JJ denotes murine
T934 33-35 IN denotes of
T935 36-43 JJ denotes classic
T936 44-48 NN denotes MSUD
T937 48-50 , denotes ,
T938 50-52 PRP denotes we
T939 58-62 NN denotes gene
T940 63-72 NN denotes targeting
T941 73-76 CC denotes and
T942 77-86 JJ denotes embryonic
T943 92-96 NN denotes cell
T944 87-91 NN denotes stem
T945 97-109 NNS denotes technologies
T946 110-112 TO denotes to
T947 113-119 VB denotes create
T948 120-121 DT denotes a
T949 128-132 NN denotes line
T950 122-127 NN denotes mouse
T951 133-137 WDT denotes that
T952 138-144 VBD denotes lacked
T953 145-146 DT denotes a
T954 169-173 NN denotes gene
T955 147-157 JJ denotes functional
T956 158-160 NN denotes E2
T957 161-168 NN denotes subunit
T958 174-176 IN denotes of
T959 177-185 VBN denotes branched
T960 186-191 NN denotes chain
T961 185-186 HYPH denotes -
T962 202-215 NN denotes dehydrogenase
T963 192-196 NN denotes keto
T964 197-201 NN denotes acid
T965 215-216 . denotes .
T966 216-348 sentence denotes To create a murine model of intermediate MSUD, we used transgenic technology to express a human E2 cDNA on the knockout background.
T967 217-219 TO denotes To
T968 220-226 VB denotes create
T969 267-271 VBD denotes used
T970 227-228 DT denotes a
T971 236-241 NN denotes model
T972 229-235 JJ denotes murine
T973 242-244 IN denotes of
T974 245-257 JJ denotes intermediate
T975 258-262 NN denotes MSUD
T976 262-264 , denotes ,
T977 264-266 PRP denotes we
T978 272-282 JJ denotes transgenic
T979 283-293 NN denotes technology
T980 294-296 TO denotes to
T981 297-304 VB denotes express
T982 305-306 DT denotes a
T983 316-320 NN denotes cDNA
T984 307-312 JJ denotes human
T985 313-315 NN denotes E2
T986 321-323 IN denotes on
T987 324-327 DT denotes the
T988 337-347 NN denotes background
T989 328-336 NN denotes knockout
T990 347-348 . denotes .
T991 348-443 sentence denotes Mice of both models were characterized at the molecular, biochemical, and whole animal levels.
T992 349-353 NNS denotes Mice
T993 374-387 VBN denotes characterized
T994 354-356 IN denotes of
T995 357-361 DT denotes both
T996 362-368 NNS denotes models
T997 369-373 VBD denotes were
T998 388-390 IN denotes at
T999 391-394 DT denotes the
T1000 436-442 NNS denotes levels
T1001 395-404 JJ denotes molecular
T1002 404-406 , denotes ,
T1003 406-417 JJ denotes biochemical
T1004 417-419 , denotes ,
T1005 419-422 CC denotes and
T1006 423-428 JJ denotes whole
T1007 429-435 NN denotes animal
T1008 442-443 . denotes .
R78 T928 T929 aux To,create
R79 T929 T930 advcl create,used
R80 T931 T932 det a,model
R81 T932 T929 dobj model,create
R83 T934 T932 prep of,model
R84 T935 T936 amod classic,MSUD
R85 T936 T934 pobj MSUD,of
R86 T937 T930 punct ", ",used
R87 T938 T930 nsubj we,used
R88 T939 T940 compound gene,targeting
R89 T940 T930 dobj targeting,used
R90 T941 T940 cc and,targeting
R91 T942 T943 amod embryonic,cell
R92 T943 T945 compound cell,technologies
R94 T945 T940 conj technologies,targeting
R95 T946 T947 aux to,create
R96 T947 T930 advcl create,used
R97 T948 T949 det a,line
R98 T949 T947 dobj line,create
R100 T951 T952 dep that,lacked
R101 T952 T949 relcl lacked,line
R102 T953 T954 det a,gene
R103 T954 T952 dobj gene,lacked
R107 T958 T954 prep of,gene
R108 T959 T960 amod branched,chain
R109 T960 T962 compound chain,dehydrogenase
R111 T962 T958 pobj dehydrogenase,of
R114 T965 T930 punct .,used
R115 T967 T968 aux To,create
R116 T968 T969 advcl create,used
R117 T970 T971 det a,model
R118 T971 T968 dobj model,create
R120 T973 T971 prep of,model
R121 T974 T975 amod intermediate,MSUD
R122 T975 T973 pobj MSUD,of
R123 T976 T969 punct ", ",used
R124 T977 T969 nsubj we,used
R125 T978 T979 amod transgenic,technology
R126 T979 T969 dobj technology,used
R127 T980 T981 aux to,express
R128 T981 T969 advcl express,used
R129 T982 T983 det a,cDNA
R130 T983 T981 dobj cDNA,express
R133 T986 T983 prep on,cDNA
R134 T987 T988 det the,background
R135 T988 T986 pobj background,on
R137 T990 T969 punct .,used
R138 T992 T993 nsubjpass Mice,characterized
R139 T994 T992 prep of,Mice
R140 T995 T996 det both,models
R141 T996 T994 pobj models,of
R142 T997 T993 auxpass were,characterized
R143 T998 T993 prep at,characterized
R144 T999 T1000 det the,levels
R145 T1000 T998 pobj levels,at
R153 T1008 T993 punct .,characterized
R82 T933 T932 amod murine,model
R93 T944 T943 compound stem,cell
R99 T950 T949 compound mouse,line
R104 T955 T954 amod functional,gene
R105 T956 T954 compound E2,gene
R106 T957 T954 compound subunit,gene
R110 T961 T960 punct -,chain
R112 T963 T964 compound keto,acid
R113 T964 T962 compound acid,dehydrogenase
R119 T972 T971 amod murine,model
R131 T984 T983 amod human,cDNA
R132 T985 T983 compound E2,cDNA
R136 T989 T988 compound knockout,background
R146 T1001 T1000 amod molecular,levels
R147 T1002 T1001 punct ", ",molecular
R148 T1003 T1001 conj biochemical,molecular
R149 T1004 T1003 punct ", ",biochemical
R150 T1005 T1003 cc and,biochemical
R151 T1006 T1007 amod whole,animal
R152 T1007 T1003 conj animal,biochemical

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T782 20-26 NCBITaxon:39107 denotes murine
T783 58-62 SO_EXT:0000704 denotes gene
T784 77-86 UBERON:0000922 denotes embryonic
T785 77-96 CL:0002322 denotes embryonic stem cell
T786 92-96 CL_GO_EXT:cell denotes cell
T787 122-127 NCBITaxon:10088 denotes mouse
T788 158-168 PR_EXT:000006300 denotes E2 subunit
T789 169-173 SO_EXT:0000704 denotes gene
T790 192-201 CHEBI:25754 denotes keto acid
T791 229-235 NCBITaxon:39107 denotes murine
T792 272-282 SO_EXT:transgenic_entity denotes transgenic
T793 297-304 GO:0010467 denotes express
T794 307-312 NCBITaxon:9606 denotes human
T795 313-315 PR_EXT:000006300 denotes E2
T796 316-320 SO_EXT:cDNA denotes cDNA
T797 349-353 NCBITaxon:10088 denotes Mice
T798 395-404 CHEBI_EXT:polyatomic_entity_or_group denotes molecular
T799 406-417 CHEBI_EXT:biochemical denotes biochemical
T800 429-435 NCBITaxon:33208 denotes animal

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T734 20-26 NCBITaxon:39107 denotes murine
T735 58-62 SO:0000704 denotes gene
T736 77-86 UBERON:0000922 denotes embryonic
T737 77-96 CL:0002322 denotes embryonic stem cell
T738 122-127 NCBITaxon:10088 denotes mouse
T739 158-168 PR:000006300 denotes E2 subunit
T740 169-173 SO:0000704 denotes gene
T741 192-201 CHEBI:25754 denotes keto acid
T742 229-235 NCBITaxon:39107 denotes murine
T743 297-304 GO:0010467 denotes express
T744 307-312 NCBITaxon:9606 denotes human
T745 313-315 PR:000006300 denotes E2
T746 349-353 NCBITaxon:10088 denotes Mice
T747 429-435 NCBITaxon:33208 denotes animal