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PMC:1440874 / 36208-37754 JSONTXT

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Id Subject Object Predicate Lexical cue
T7415 0-4 NN denotes Atrx
T7416 5-7 IN denotes in
T7417 8-10 NN denotes ES
T7418 11-16 NNS denotes Cells
T7419 16-153 sentence denotes Atrxnull ES cells could not be recovered by direct targeting and were eventually generated by adopting a conditional targeting approach.
T7420 17-25 JJ denotes Atrxnull
T7421 26-28 NN denotes ES
T7422 29-34 NNS denotes cells
T7423 48-57 VBN denotes recovered
T7424 35-40 MD denotes could
T7425 41-44 RB denotes not
T7426 45-47 VB denotes be
T7427 58-60 IN denotes by
T7428 61-67 JJ denotes direct
T7429 68-77 NN denotes targeting
T7430 78-81 CC denotes and
T7431 82-86 VBD denotes were
T7432 98-107 VBN denotes generated
T7433 87-97 RB denotes eventually
T7434 108-110 IN denotes by
T7435 111-119 VBG denotes adopting
T7436 120-121 DT denotes a
T7437 144-152 NN denotes approach
T7438 122-133 JJ denotes conditional
T7439 134-143 NN denotes targeting
T7440 152-153 . denotes .
T7441 153-359 sentence denotes This is consistent with our observation that Atrx is highly expressed in ES cells, and that the absence of full-length Atrx imparts a growth disadvantage relative to cells bearing a functional Atrx allele.
T7442 154-158 DT denotes This
T7443 159-161 VBZ denotes is
T7444 162-172 JJ denotes consistent
T7445 173-177 IN denotes with
T7446 178-181 PRP$ denotes our
T7447 182-193 NN denotes observation
T7448 194-198 IN denotes that
T7449 204-206 VBZ denotes is
T7450 199-203 NN denotes Atrx
T7451 207-213 RB denotes highly
T7452 214-223 JJ denotes expressed
T7453 224-226 IN denotes in
T7454 227-229 NN denotes ES
T7455 230-235 NNS denotes cells
T7456 235-237 , denotes ,
T7457 237-240 CC denotes and
T7458 241-245 IN denotes that
T7459 278-285 VBZ denotes imparts
T7460 246-249 DT denotes the
T7461 250-257 NN denotes absence
T7462 258-260 IN denotes of
T7463 261-265 JJ denotes full
T7464 266-272 NN denotes length
T7465 265-266 HYPH denotes -
T7466 273-277 NN denotes Atrx
T7467 286-287 DT denotes a
T7468 295-307 NN denotes disadvantage
T7469 288-294 NN denotes growth
T7470 308-316 JJ denotes relative
T7471 317-319 IN denotes to
T7472 320-325 NNS denotes cells
T7473 326-333 VBG denotes bearing
T7474 334-335 DT denotes a
T7475 352-358 NN denotes allele
T7476 336-346 JJ denotes functional
T7477 347-351 NN denotes Atrx
T7478 358-359 . denotes .
T7479 359-443 sentence denotes At present, the cause of the proliferative delay in Atrxnull ES cells is not known.
T7480 360-362 IN denotes At
T7481 430-432 VBZ denotes is
T7482 363-370 JJ denotes present
T7483 370-372 , denotes ,
T7484 372-375 DT denotes the
T7485 376-381 NN denotes cause
T7486 382-384 IN denotes of
T7487 385-388 DT denotes the
T7488 403-408 NN denotes delay
T7489 389-402 JJ denotes proliferative
T7490 409-411 IN denotes in
T7491 412-420 JJ denotes Atrxnull
T7492 424-429 NNS denotes cells
T7493 421-423 NN denotes ES
T7494 433-436 RB denotes not
T7495 437-442 JJ denotes known
T7496 442-443 . denotes .
T7497 443-611 sentence denotes Interestingly, we demonstrated that apoptosis is not significantly up-regulated in ES cells lacking Atrx and is only mildly elevated in Atrxnull 7.5 dpc mouse embryos.
T7498 444-457 RB denotes Interestingly
T7499 462-474 VBD denotes demonstrated
T7500 457-459 , denotes ,
T7501 459-461 PRP denotes we
T7502 475-479 IN denotes that
T7503 514-523 VBN denotes regulated
T7504 480-489 NN denotes apoptosis
T7505 490-492 VBZ denotes is
T7506 493-496 RB denotes not
T7507 497-510 RB denotes significantly
T7508 511-513 RB denotes up
T7509 513-514 HYPH denotes -
T7510 524-526 IN denotes in
T7511 527-529 NN denotes ES
T7512 530-535 NNS denotes cells
T7513 536-543 VBG denotes lacking
T7514 544-548 NN denotes Atrx
T7515 549-552 CC denotes and
T7516 553-555 VBZ denotes is
T7517 556-560 RB denotes only
T7518 561-567 RB denotes mildly
T7519 568-576 JJ denotes elevated
T7520 577-579 IN denotes in
T7521 580-588 JJ denotes Atrxnull
T7522 603-610 NNS denotes embryos
T7523 589-592 CD denotes 7.5
T7524 593-596 NN denotes dpc
T7525 597-602 NN denotes mouse
T7526 610-611 . denotes .
T7527 611-907 sentence denotes In contrast, it was recently shown that the loss of Atrx markedly increased the apoptotic population in the differentiating cells of the embryonic cortex and postnatal hippocampus, when Atrx expression was ablated in the developing mouse forebrain using the Atrx flox allele described here [20].
T7528 612-614 IN denotes In
T7529 641-646 VBN denotes shown
T7530 615-623 NN denotes contrast
T7531 623-625 , denotes ,
T7532 625-627 PRP denotes it
T7533 628-631 VBD denotes was
T7534 632-640 RB denotes recently
T7535 647-651 IN denotes that
T7536 678-687 VBD denotes increased
T7537 652-655 DT denotes the
T7538 656-660 NN denotes loss
T7539 661-663 IN denotes of
T7540 664-668 NN denotes Atrx
T7541 669-677 RB denotes markedly
T7542 688-691 DT denotes the
T7543 702-712 NN denotes population
T7544 692-701 JJ denotes apoptotic
T7545 713-715 IN denotes in
T7546 716-719 DT denotes the
T7547 736-741 NNS denotes cells
T7548 720-735 VBG denotes differentiating
T7549 742-744 IN denotes of
T7550 745-748 DT denotes the
T7551 759-765 NN denotes cortex
T7552 749-758 JJ denotes embryonic
T7553 766-769 CC denotes and
T7554 770-779 JJ denotes postnatal
T7555 780-791 NN denotes hippocampus
T7556 791-793 , denotes ,
T7557 793-797 WRB denotes when
T7558 818-825 VBN denotes ablated
T7559 798-802 NN denotes Atrx
T7560 803-813 NN denotes expression
T7561 814-817 VBD denotes was
T7562 826-828 IN denotes in
T7563 829-832 DT denotes the
T7564 850-859 NN denotes forebrain
T7565 833-843 VBG denotes developing
T7566 844-849 NN denotes mouse
T7567 860-865 VBG denotes using
T7568 866-869 DT denotes the
T7569 880-886 NN denotes allele
T7570 870-879 NN denotes Atrx flox
T7571 887-896 VBN denotes described
T7572 897-901 RB denotes here
T7573 902-903 -LRB- denotes [
T7574 903-905 CD denotes 20
T7575 905-906 -RRB- denotes ]
T7576 906-907 . denotes .
T7577 907-1080 sentence denotes The human ATRX protein has been shown to associate in a complex with Daxx [8], a protein that has been implicated in multiple pathways for the regulation of apoptosis [21].
T7578 908-911 DT denotes The
T7579 923-930 NN denotes protein
T7580 912-917 JJ denotes human
T7581 918-922 NN denotes ATRX
T7582 940-945 VBN denotes shown
T7583 931-934 VBZ denotes has
T7584 935-939 VBN denotes been
T7585 946-948 TO denotes to
T7586 949-958 VB denotes associate
T7587 959-961 IN denotes in
T7588 962-963 DT denotes a
T7589 964-971 NN denotes complex
T7590 972-976 IN denotes with
T7591 977-981 NN denotes Daxx
T7592 982-983 -LRB- denotes [
T7593 983-984 CD denotes 8
T7594 984-985 -RRB- denotes ]
T7595 985-987 , denotes ,
T7596 987-988 DT denotes a
T7597 989-996 NN denotes protein
T7598 997-1001 WDT denotes that
T7599 1011-1021 VBN denotes implicated
T7600 1002-1005 VBZ denotes has
T7601 1006-1010 VBN denotes been
T7602 1022-1024 IN denotes in
T7603 1025-1033 JJ denotes multiple
T7604 1034-1042 NNS denotes pathways
T7605 1043-1046 IN denotes for
T7606 1047-1050 DT denotes the
T7607 1051-1061 NN denotes regulation
T7608 1062-1064 IN denotes of
T7609 1065-1074 NN denotes apoptosis
T7610 1075-1076 -LRB- denotes [
T7611 1076-1078 CD denotes 21
T7612 1078-1079 -RRB- denotes ]
T7613 1079-1080 . denotes .
T7614 1080-1232 sentence denotes It is possible that disruption of the mouse Atrx-Daxx complex (by ablation of the Atrx protein) could have triggered a universal proapoptotic response.
T7615 1081-1083 PRP denotes It
T7616 1084-1086 VBZ denotes is
T7617 1087-1095 JJ denotes possible
T7618 1096-1100 IN denotes that
T7619 1188-1197 VBN denotes triggered
T7620 1101-1111 NN denotes disruption
T7621 1112-1114 IN denotes of
T7622 1115-1118 DT denotes the
T7623 1135-1142 NN denotes complex
T7624 1119-1124 NN denotes mouse
T7625 1125-1129 NN denotes Atrx
T7626 1130-1134 NN denotes Daxx
T7627 1129-1130 HYPH denotes -
T7628 1143-1144 -LRB- denotes (
T7629 1144-1146 IN denotes by
T7630 1147-1155 NN denotes ablation
T7631 1156-1158 IN denotes of
T7632 1159-1162 DT denotes the
T7633 1168-1175 NN denotes protein
T7634 1163-1167 NN denotes Atrx
T7635 1175-1176 -RRB- denotes )
T7636 1177-1182 MD denotes could
T7637 1183-1187 VB denotes have
T7638 1198-1199 DT denotes a
T7639 1223-1231 NN denotes response
T7640 1200-1209 JJ denotes universal
T7641 1210-1222 JJ denotes proapoptotic
T7642 1231-1232 . denotes .
T7643 1232-1546 sentence denotes However, our observations in ES cells demonstrate that the induction of apoptosis is not an automatic response triggered by the removal of Atrx in all cell types, and suggest that the inappropriate apoptosis observed in the Atrx-mutant forebrain may reflect a requirement for Atrx during terminal differentiation.
T7644 1233-1240 RB denotes However
T7645 1271-1282 VBP denotes demonstrate
T7646 1240-1242 , denotes ,
T7647 1242-1245 PRP$ denotes our
T7648 1246-1258 NNS denotes observations
T7649 1259-1261 IN denotes in
T7650 1262-1264 NN denotes ES
T7651 1265-1270 NNS denotes cells
T7652 1283-1287 IN denotes that
T7653 1315-1317 VBZ denotes is
T7654 1288-1291 DT denotes the
T7655 1292-1301 NN denotes induction
T7656 1302-1304 IN denotes of
T7657 1305-1314 NN denotes apoptosis
T7658 1318-1321 RB denotes not
T7659 1322-1324 DT denotes an
T7660 1335-1343 NN denotes response
T7661 1325-1334 JJ denotes automatic
T7662 1344-1353 VBN denotes triggered
T7663 1354-1356 IN denotes by
T7664 1357-1360 DT denotes the
T7665 1361-1368 NN denotes removal
T7666 1369-1371 IN denotes of
T7667 1372-1376 NN denotes Atrx
T7668 1377-1379 IN denotes in
T7669 1380-1383 DT denotes all
T7670 1389-1394 NNS denotes types
T7671 1384-1388 NN denotes cell
T7672 1394-1396 , denotes ,
T7673 1396-1399 CC denotes and
T7674 1400-1407 VBP denotes suggest
T7675 1408-1412 IN denotes that
T7676 1483-1490 VB denotes reflect
T7677 1413-1416 DT denotes the
T7678 1431-1440 NN denotes apoptosis
T7679 1417-1430 JJ denotes inappropriate
T7680 1441-1449 VBN denotes observed
T7681 1450-1452 IN denotes in
T7682 1453-1456 DT denotes the
T7683 1469-1478 NN denotes forebrain
T7684 1457-1461 NN denotes Atrx
T7685 1462-1468 NN denotes mutant
T7686 1461-1462 HYPH denotes -
T7687 1479-1482 MD denotes may
T7688 1491-1492 DT denotes a
T7689 1493-1504 NN denotes requirement
T7690 1505-1508 IN denotes for
T7691 1509-1513 NN denotes Atrx
T7692 1514-1520 IN denotes during
T7693 1521-1529 JJ denotes terminal
T7694 1530-1545 NN denotes differentiation
T7695 1545-1546 . denotes .
R4550 T7416 T7415 prep in,Atrx
R4551 T7417 T7418 compound ES,Cells
R4552 T7418 T7416 pobj Cells,in
R4553 T7420 T7421 amod Atrxnull,ES
R4554 T7421 T7422 compound ES,cells
R4555 T7422 T7423 nsubjpass cells,recovered
R4556 T7424 T7423 aux could,recovered
R4557 T7425 T7423 neg not,recovered
R4558 T7426 T7423 auxpass be,recovered
R4559 T7427 T7423 agent by,recovered
R4560 T7428 T7429 amod direct,targeting
R4561 T7429 T7427 pobj targeting,by
R4562 T7430 T7423 cc and,recovered
R4563 T7431 T7432 auxpass were,generated
R4564 T7432 T7423 conj generated,recovered
R4565 T7433 T7432 advmod eventually,generated
R4566 T7434 T7432 prep by,generated
R4567 T7435 T7434 pcomp adopting,by
R4568 T7436 T7437 det a,approach
R4569 T7437 T7435 dobj approach,adopting
R4570 T7438 T7439 amod conditional,targeting
R4571 T7439 T7437 compound targeting,approach
R4572 T7440 T7423 punct .,recovered
R4573 T7442 T7443 nsubj This,is
R4574 T7444 T7443 acomp consistent,is
R4575 T7445 T7444 prep with,consistent
R4576 T7446 T7447 poss our,observation
R4577 T7447 T7445 pobj observation,with
R4578 T7448 T7449 mark that,is
R4579 T7449 T7447 advcl is,observation
R4580 T7450 T7449 nsubj Atrx,is
R4581 T7451 T7452 advmod highly,expressed
R4582 T7452 T7449 acomp expressed,is
R4583 T7453 T7449 prep in,is
R4584 T7454 T7455 compound ES,cells
R4585 T7455 T7453 pobj cells,in
R4586 T7456 T7449 punct ", ",is
R4587 T7457 T7449 cc and,is
R4588 T7458 T7459 mark that,imparts
R4589 T7459 T7449 conj imparts,is
R4590 T7460 T7461 det the,absence
R4591 T7461 T7459 nsubj absence,imparts
R4592 T7462 T7461 prep of,absence
R4593 T7463 T7464 amod full,length
R4594 T7464 T7466 compound length,Atrx
R4595 T7465 T7464 punct -,length
R4596 T7466 T7462 pobj Atrx,of
R4597 T7467 T7468 det a,disadvantage
R4598 T7468 T7459 dobj disadvantage,imparts
R4599 T7469 T7468 compound growth,disadvantage
R4600 T7470 T7459 advcl relative,imparts
R4601 T7471 T7470 prep to,relative
R4602 T7472 T7471 pobj cells,to
R4603 T7473 T7472 acl bearing,cells
R4604 T7474 T7475 det a,allele
R4605 T7475 T7473 dobj allele,bearing
R4606 T7476 T7475 amod functional,allele
R4607 T7477 T7475 compound Atrx,allele
R4608 T7478 T7443 punct .,is
R4609 T7480 T7481 prep At,is
R4610 T7482 T7480 amod present,At
R4611 T7483 T7481 punct ", ",is
R4612 T7484 T7485 det the,cause
R4613 T7485 T7481 nsubj cause,is
R4614 T7486 T7485 prep of,cause
R4615 T7487 T7488 det the,delay
R4616 T7488 T7486 pobj delay,of
R4617 T7489 T7488 amod proliferative,delay
R4618 T7490 T7488 prep in,delay
R4619 T7491 T7492 amod Atrxnull,cells
R4620 T7492 T7490 pobj cells,in
R4621 T7493 T7492 compound ES,cells
R4622 T7494 T7481 neg not,is
R4623 T7495 T7481 acomp known,is
R4624 T7496 T7481 punct .,is
R4625 T7498 T7499 advmod Interestingly,demonstrated
R4626 T7500 T7499 punct ", ",demonstrated
R4627 T7501 T7499 nsubj we,demonstrated
R4628 T7502 T7503 mark that,regulated
R4629 T7503 T7499 ccomp regulated,demonstrated
R4630 T7504 T7503 nsubjpass apoptosis,regulated
R4631 T7505 T7503 auxpass is,regulated
R4632 T7506 T7503 neg not,regulated
R4633 T7507 T7503 advmod significantly,regulated
R4634 T7508 T7503 advmod up,regulated
R4635 T7509 T7503 punct -,regulated
R4636 T7510 T7503 prep in,regulated
R4637 T7511 T7512 compound ES,cells
R4638 T7512 T7510 pobj cells,in
R4639 T7513 T7512 acl lacking,cells
R4640 T7514 T7513 dobj Atrx,lacking
R4641 T7515 T7503 cc and,regulated
R4642 T7516 T7503 conj is,regulated
R4643 T7517 T7518 advmod only,mildly
R4644 T7518 T7519 advmod mildly,elevated
R4645 T7519 T7516 acomp elevated,is
R4646 T7520 T7516 prep in,is
R4647 T7521 T7522 amod Atrxnull,embryos
R4648 T7522 T7520 pobj embryos,in
R4649 T7523 T7524 nummod 7.5,dpc
R4650 T7524 T7522 compound dpc,embryos
R4651 T7525 T7522 compound mouse,embryos
R4652 T7526 T7499 punct .,demonstrated
R4653 T7528 T7529 prep In,shown
R4654 T7530 T7528 pobj contrast,In
R4655 T7531 T7529 punct ", ",shown
R4656 T7532 T7529 nsubjpass it,shown
R4657 T7533 T7529 auxpass was,shown
R4658 T7534 T7529 advmod recently,shown
R4659 T7535 T7536 mark that,increased
R4660 T7536 T7529 ccomp increased,shown
R4661 T7537 T7538 det the,loss
R4662 T7538 T7536 nsubj loss,increased
R4663 T7539 T7538 prep of,loss
R4664 T7540 T7539 pobj Atrx,of
R4665 T7541 T7536 advmod markedly,increased
R4666 T7542 T7543 det the,population
R4667 T7543 T7536 dobj population,increased
R4668 T7544 T7543 amod apoptotic,population
R4669 T7545 T7536 prep in,increased
R4670 T7546 T7547 det the,cells
R4671 T7547 T7545 pobj cells,in
R4672 T7548 T7547 amod differentiating,cells
R4673 T7549 T7547 prep of,cells
R4674 T7550 T7551 det the,cortex
R4675 T7551 T7549 pobj cortex,of
R4676 T7552 T7551 amod embryonic,cortex
R4677 T7553 T7551 cc and,cortex
R4678 T7554 T7555 amod postnatal,hippocampus
R4679 T7555 T7551 conj hippocampus,cortex
R4680 T7556 T7536 punct ", ",increased
R4681 T7557 T7558 advmod when,ablated
R4682 T7558 T7536 advcl ablated,increased
R4683 T7559 T7560 compound Atrx,expression
R4684 T7560 T7558 nsubjpass expression,ablated
R4685 T7561 T7558 auxpass was,ablated
R4686 T7562 T7558 prep in,ablated
R4687 T7563 T7564 det the,forebrain
R4688 T7564 T7562 pobj forebrain,in
R4689 T7565 T7564 amod developing,forebrain
R4690 T7566 T7564 compound mouse,forebrain
R4691 T7567 T7536 advcl using,increased
R4692 T7568 T7569 det the,allele
R4693 T7569 T7567 dobj allele,using
R4694 T7570 T7569 compound Atrx flox,allele
R4695 T7571 T7569 acl described,allele
R4696 T7572 T7571 advmod here,described
R4697 T7573 T7574 punct [,20
R4698 T7574 T7529 parataxis 20,shown
R4699 T7575 T7574 punct ],20
R4700 T7576 T7529 punct .,shown
R4701 T7578 T7579 det The,protein
R4702 T7579 T7582 nsubjpass protein,shown
R4703 T7580 T7579 amod human,protein
R4704 T7581 T7579 compound ATRX,protein
R4705 T7583 T7582 aux has,shown
R4706 T7584 T7582 auxpass been,shown
R4707 T7585 T7586 aux to,associate
R4708 T7586 T7582 xcomp associate,shown
R4709 T7587 T7586 prep in,associate
R4710 T7588 T7589 det a,complex
R4711 T7589 T7587 pobj complex,in
R4712 T7590 T7586 prep with,associate
R4713 T7591 T7590 pobj Daxx,with
R4714 T7592 T7593 punct [,8
R4715 T7593 T7591 parataxis 8,Daxx
R4716 T7594 T7593 punct ],8
R4717 T7595 T7591 punct ", ",Daxx
R4718 T7596 T7597 det a,protein
R4719 T7597 T7591 appos protein,Daxx
R4720 T7598 T7599 dep that,implicated
R4721 T7599 T7597 relcl implicated,protein
R4722 T7600 T7599 aux has,implicated
R4723 T7601 T7599 auxpass been,implicated
R4724 T7602 T7599 prep in,implicated
R4725 T7603 T7604 amod multiple,pathways
R4726 T7604 T7602 pobj pathways,in
R4727 T7605 T7599 prep for,implicated
R4728 T7606 T7607 det the,regulation
R4729 T7607 T7605 pobj regulation,for
R4730 T7608 T7607 prep of,regulation
R4731 T7609 T7608 pobj apoptosis,of
R4732 T7610 T7611 punct [,21
R4733 T7611 T7582 parataxis 21,shown
R4734 T7612 T7611 punct ],21
R4735 T7613 T7582 punct .,shown
R4736 T7615 T7616 nsubj It,is
R4737 T7617 T7616 acomp possible,is
R4738 T7618 T7619 mark that,triggered
R4739 T7619 T7616 ccomp triggered,is
R4740 T7620 T7619 nsubj disruption,triggered
R4741 T7621 T7620 prep of,disruption
R4742 T7622 T7623 det the,complex
R4743 T7623 T7621 pobj complex,of
R4744 T7624 T7623 compound mouse,complex
R4745 T7625 T7626 compound Atrx,Daxx
R4746 T7626 T7623 compound Daxx,complex
R4747 T7627 T7626 punct -,Daxx
R4748 T7628 T7620 punct (,disruption
R4749 T7629 T7620 prep by,disruption
R4750 T7630 T7629 pobj ablation,by
R4751 T7631 T7630 prep of,ablation
R4752 T7632 T7633 det the,protein
R4753 T7633 T7631 pobj protein,of
R4754 T7634 T7633 compound Atrx,protein
R4755 T7635 T7619 punct ),triggered
R4756 T7636 T7619 aux could,triggered
R4757 T7637 T7619 aux have,triggered
R4758 T7638 T7639 det a,response
R4759 T7639 T7619 dobj response,triggered
R4760 T7640 T7639 amod universal,response
R4761 T7641 T7639 amod proapoptotic,response
R4762 T7642 T7616 punct .,is
R4763 T7644 T7645 advmod However,demonstrate
R4764 T7646 T7645 punct ", ",demonstrate
R4765 T7647 T7648 poss our,observations
R4766 T7648 T7645 nsubj observations,demonstrate
R4767 T7649 T7648 prep in,observations
R4768 T7650 T7651 compound ES,cells
R4769 T7651 T7649 pobj cells,in
R4770 T7652 T7653 mark that,is
R4771 T7653 T7645 ccomp is,demonstrate
R4772 T7654 T7655 det the,induction
R4773 T7655 T7653 nsubj induction,is
R4774 T7656 T7655 prep of,induction
R4775 T7657 T7656 pobj apoptosis,of
R4776 T7658 T7653 neg not,is
R4777 T7659 T7660 det an,response
R4778 T7660 T7653 attr response,is
R4779 T7661 T7660 amod automatic,response
R4780 T7662 T7660 acl triggered,response
R4781 T7663 T7662 agent by,triggered
R4782 T7664 T7665 det the,removal
R4783 T7665 T7663 pobj removal,by
R4784 T7666 T7665 prep of,removal
R4785 T7667 T7666 pobj Atrx,of
R4786 T7668 T7662 prep in,triggered
R4787 T7669 T7670 det all,types
R4788 T7670 T7668 pobj types,in
R4789 T7671 T7670 compound cell,types
R4790 T7672 T7645 punct ", ",demonstrate
R4791 T7673 T7645 cc and,demonstrate
R4792 T7674 T7645 conj suggest,demonstrate
R4793 T7675 T7676 mark that,reflect
R4794 T7676 T7674 ccomp reflect,suggest
R4795 T7677 T7678 det the,apoptosis
R4796 T7678 T7676 nsubj apoptosis,reflect
R4797 T7679 T7678 amod inappropriate,apoptosis
R4798 T7680 T7678 acl observed,apoptosis
R4799 T7681 T7680 prep in,observed
R4800 T7682 T7683 det the,forebrain
R4801 T7683 T7681 pobj forebrain,in
R4802 T7684 T7685 compound Atrx,mutant
R4803 T7685 T7683 compound mutant,forebrain
R4804 T7686 T7685 punct -,mutant
R4805 T7687 T7676 aux may,reflect
R4806 T7688 T7689 det a,requirement
R4807 T7689 T7676 dobj requirement,reflect
R4808 T7690 T7689 prep for,requirement
R4809 T7691 T7690 pobj Atrx,for
R4810 T7692 T7689 prep during,requirement
R4811 T7693 T7694 amod terminal,differentiation
R4812 T7694 T7692 pobj differentiation,during
R4813 T7695 T7645 punct .,demonstrate

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7343 0-4 PR_EXT:000004503 denotes Atrx
T7344 8-16 CL:0002322 denotes ES Cells
T7345 11-16 CL_GO_EXT:cell denotes Cells
T7346 17-21 PR_EXT:000004503 denotes Atrx
T7347 21-25 SO_EXT:sequence_nullness denotes null
T7348 26-34 CL:0002322 denotes ES cells
T7349 29-34 CL_GO_EXT:cell denotes cells
T7350 199-203 PR_EXT:000004503 denotes Atrx
T7351 214-223 GO:0010467 denotes expressed
T7352 227-235 CL:0002322 denotes ES cells
T7353 230-235 CL_GO_EXT:cell denotes cells
T7354 273-277 PR_EXT:000004503 denotes Atrx
T7355 288-294 GO_EXT:biological_growth_entity_or_process denotes growth
T7356 320-325 CL_GO_EXT:cell denotes cells
T7357 347-351 PR_EXT:000004503 denotes Atrx
T7358 352-358 SO_EXT:0001023 denotes allele
T7359 389-402 GO_PATO_EXT:cell_proliferation_or_proliferativity denotes proliferative
T7360 412-416 PR_EXT:000004503 denotes Atrx
T7361 416-420 SO_EXT:sequence_nullness denotes null
T7362 421-429 CL:0002322 denotes ES cells
T7363 424-429 CL_GO_EXT:cell denotes cells
T7364 480-489 GO:0006915 denotes apoptosis
T7365 511-523 GO_EXT:positive_regulation denotes up-regulated
T7366 527-535 CL:0002322 denotes ES cells
T7367 530-535 CL_GO_EXT:cell denotes cells
T7368 544-548 PR_EXT:000004503 denotes Atrx
T7369 580-584 PR_EXT:000004503 denotes Atrx
T7370 584-588 SO_EXT:sequence_nullness denotes null
T7371 597-602 NCBITaxon:10088 denotes mouse
T7372 603-610 UBERON:0000922 denotes embryos
T7373 664-668 PR_EXT:000004503 denotes Atrx
T7374 692-701 GO_PATO_EXT:apoptotic_process_or_quality denotes apoptotic
T7375 720-735 GO_RO_EXT:developmental_differentiation_process denotes differentiating
T7376 736-741 CL_GO_EXT:cell denotes cells
T7377 749-758 UBERON:0000922 denotes embryonic
T7378 759-765 UBERON:0001851 denotes cortex
T7379 774-779 GO:0007567 denotes natal
T7380 780-791 UBERON_EXT:hippocampus_proper_or_hippocampal_formation denotes hippocampus
T7381 798-802 PR_EXT:000004503 denotes Atrx
T7382 803-813 GO:0010467 denotes expression
T7383 844-849 NCBITaxon:10088 denotes mouse
T7384 850-859 UBERON:0001890 denotes forebrain
T7385 870-874 PR_EXT:000004503 denotes Atrx
T7386 875-879 SO:0000359 denotes flox
T7387 880-886 SO_EXT:0001023 denotes allele
T7388 912-917 NCBITaxon:9606 denotes human
T7389 918-922 PR_EXT:000004503 denotes ATRX
T7390 923-930 CHEBI_PR_EXT:protein denotes protein
T7391 964-971 GO:0032991 denotes complex
T7392 977-981 PR_EXT:000006283 denotes Daxx
T7393 989-996 CHEBI_PR_EXT:protein denotes protein
T7394 1051-1074 GO:0042981 denotes regulation of apoptosis
T7395 1119-1124 NCBITaxon:10088 denotes mouse
T7396 1125-1129 PR_EXT:000004503 denotes Atrx
T7397 1130-1134 PR_EXT:000006283 denotes Daxx
T7398 1135-1142 GO:0032991 denotes complex
T7399 1163-1167 PR_EXT:000004503 denotes Atrx
T7400 1168-1175 CHEBI_PR_EXT:protein denotes protein
T7401 1213-1222 GO_PATO_EXT:apoptotic_process_or_quality denotes apoptotic
T7402 1223-1231 GO_EXT:reaction_or_response denotes response
T7403 1262-1270 CL:0002322 denotes ES cells
T7404 1265-1270 CL_GO_EXT:cell denotes cells
T7405 1305-1314 GO:0006915 denotes apoptosis
T7406 1335-1343 GO_EXT:reaction_or_response denotes response
T7407 1372-1376 PR_EXT:000004503 denotes Atrx
T7408 1384-1388 CL_GO_EXT:cell denotes cell
T7409 1431-1440 GO:0006915 denotes apoptosis
T7410 1457-1461 PR_EXT:000004503 denotes Atrx
T7411 1462-1468 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T7412 1469-1478 UBERON:0001890 denotes forebrain
T7413 1509-1513 PR_EXT:000004503 denotes Atrx
T7414 1530-1545 GO_RO_EXT:developmental_differentiation_process denotes differentiation

2_test

Id Subject Object Predicate Lexical cue
16628246-15668733-85799759 903-905 15668733 denotes 20
16628246-12953102-85799760 983-984 12953102 denotes 8
16628246-15077145-85799761 1076-1078 15077145 denotes 21
T69494 903-905 15668733 denotes 20
T51832 983-984 12953102 denotes 8
T83532 1076-1078 15077145 denotes 21

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7297 0-4 PR:000004503 denotes Atrx
T7298 8-16 CL:0002322 denotes ES Cells
T7299 17-21 PR:000004503 denotes Atrx
T7300 26-34 CL:0002322 denotes ES cells
T7301 199-203 PR:000004503 denotes Atrx
T7302 214-223 GO:0010467 denotes expressed
T7303 227-235 CL:0002322 denotes ES cells
T7304 273-277 PR:000004503 denotes Atrx
T7305 347-351 PR:000004503 denotes Atrx
T7306 352-358 SO:0001023 denotes allele
T7307 412-416 PR:000004503 denotes Atrx
T7308 421-429 CL:0002322 denotes ES cells
T7309 480-489 GO:0006915 denotes apoptosis
T7310 527-535 CL:0002322 denotes ES cells
T7311 544-548 PR:000004503 denotes Atrx
T7312 580-584 PR:000004503 denotes Atrx
T7313 597-602 NCBITaxon:10088 denotes mouse
T7314 603-610 UBERON:0000922 denotes embryos
T7315 664-668 PR:000004503 denotes Atrx
T7316 749-758 UBERON:0000922 denotes embryonic
T7317 759-765 UBERON:0001851 denotes cortex
T7318 774-779 GO:0007567 denotes natal
T7319 798-802 PR:000004503 denotes Atrx
T7320 803-813 GO:0010467 denotes expression
T7321 844-849 NCBITaxon:10088 denotes mouse
T7322 850-859 UBERON:0001890 denotes forebrain
T7323 870-874 PR:000004503 denotes Atrx
T7324 875-879 SO:0000359 denotes flox
T7325 880-886 SO:0001023 denotes allele
T7326 912-917 NCBITaxon:9606 denotes human
T7327 918-922 PR:000004503 denotes ATRX
T7328 964-971 GO:0032991 denotes complex
T7329 977-981 PR:000006283 denotes Daxx
T7330 1051-1074 GO:0042981 denotes regulation of apoptosis
T7331 1119-1124 NCBITaxon:10088 denotes mouse
T7332 1125-1129 PR:000004503 denotes Atrx
T7333 1130-1134 PR:000006283 denotes Daxx
T7334 1135-1142 GO:0032991 denotes complex
T7335 1163-1167 PR:000004503 denotes Atrx
T7336 1262-1270 CL:0002322 denotes ES cells
T7337 1305-1314 GO:0006915 denotes apoptosis
T7338 1372-1376 PR:000004503 denotes Atrx
T7339 1431-1440 GO:0006915 denotes apoptosis
T7340 1457-1461 PR:000004503 denotes Atrx
T7341 1469-1478 UBERON:0001890 denotes forebrain
T7342 1509-1513 PR:000004503 denotes Atrx