Id |
Subject |
Object |
Predicate |
Lexical cue |
T1125 |
0-7 |
NNS |
denotes |
Results |
T1126 |
7-163 |
sentence |
denotes |
mr-s is evolutionarily conserved from zebrafish through human, organisms through which the mechanism of photoreceptor development is also highly conserved. |
T1127 |
8-10 |
NN |
denotes |
mr |
T1128 |
11-12 |
NN |
denotes |
s |
T1129 |
10-11 |
HYPH |
denotes |
- |
T1130 |
31-40 |
VBN |
denotes |
conserved |
T1131 |
13-15 |
VBZ |
denotes |
is |
T1132 |
16-30 |
RB |
denotes |
evolutionarily |
T1133 |
41-45 |
IN |
denotes |
from |
T1134 |
46-55 |
NN |
denotes |
zebrafish |
T1135 |
56-63 |
IN |
denotes |
through |
T1136 |
64-69 |
JJ |
denotes |
human |
T1137 |
69-71 |
, |
denotes |
, |
T1138 |
71-80 |
NNS |
denotes |
organisms |
T1139 |
81-88 |
IN |
denotes |
through |
T1140 |
153-162 |
VBN |
denotes |
conserved |
T1141 |
89-94 |
WDT |
denotes |
which |
T1142 |
95-98 |
DT |
denotes |
the |
T1143 |
99-108 |
NN |
denotes |
mechanism |
T1144 |
109-111 |
IN |
denotes |
of |
T1145 |
112-125 |
NN |
denotes |
photoreceptor |
T1146 |
126-137 |
NN |
denotes |
development |
T1147 |
138-140 |
VBZ |
denotes |
is |
T1148 |
141-145 |
RB |
denotes |
also |
T1149 |
146-152 |
RB |
denotes |
highly |
T1150 |
162-163 |
. |
denotes |
. |
T1151 |
163-375 |
sentence |
denotes |
Phylogenetic analysis suggests that the SAM domain of mr-s is most closely related to a mouse polyhomeotic (ph) ortholog, Mph1/Rae28, which is known as an epigenetic molecule involved in chromatin modifications. |
T1152 |
164-176 |
JJ |
denotes |
Phylogenetic |
T1153 |
177-185 |
NN |
denotes |
analysis |
T1154 |
186-194 |
VBZ |
denotes |
suggests |
T1155 |
195-199 |
IN |
denotes |
that |
T1156 |
239-246 |
VBN |
denotes |
related |
T1157 |
200-203 |
DT |
denotes |
the |
T1158 |
208-214 |
NN |
denotes |
domain |
T1159 |
204-207 |
NN |
denotes |
SAM |
T1160 |
215-217 |
IN |
denotes |
of |
T1161 |
218-220 |
NN |
denotes |
mr |
T1162 |
221-222 |
NN |
denotes |
s |
T1163 |
220-221 |
HYPH |
denotes |
- |
T1164 |
223-225 |
VBZ |
denotes |
is |
T1165 |
226-230 |
RBS |
denotes |
most |
T1166 |
231-238 |
RB |
denotes |
closely |
T1167 |
247-249 |
IN |
denotes |
to |
T1168 |
250-251 |
DT |
denotes |
a |
T1169 |
276-284 |
NN |
denotes |
ortholog |
T1170 |
252-257 |
NN |
denotes |
mouse |
T1171 |
258-270 |
NN |
denotes |
polyhomeotic |
T1172 |
271-272 |
-LRB- |
denotes |
( |
T1173 |
272-274 |
NN |
denotes |
ph |
T1174 |
274-275 |
-RRB- |
denotes |
) |
T1175 |
284-286 |
, |
denotes |
, |
T1176 |
286-290 |
NN |
denotes |
Mph1 |
T1177 |
291-296 |
NN |
denotes |
Rae28 |
T1178 |
290-291 |
HYPH |
denotes |
/ |
T1179 |
296-298 |
, |
denotes |
, |
T1180 |
298-303 |
WDT |
denotes |
which |
T1181 |
307-312 |
VBN |
denotes |
known |
T1182 |
304-306 |
VBZ |
denotes |
is |
T1183 |
313-315 |
IN |
denotes |
as |
T1184 |
316-318 |
DT |
denotes |
an |
T1185 |
330-338 |
NN |
denotes |
molecule |
T1186 |
319-329 |
JJ |
denotes |
epigenetic |
T1187 |
339-347 |
VBN |
denotes |
involved |
T1188 |
348-350 |
IN |
denotes |
in |
T1189 |
351-360 |
NN |
denotes |
chromatin |
T1190 |
361-374 |
NNS |
denotes |
modifications |
T1191 |
374-375 |
. |
denotes |
. |
T1192 |
375-509 |
sentence |
denotes |
These findings provide the possibility that mr-s may play a critical role by regulating gene expression in photoreceptor development. |
T1193 |
376-381 |
DT |
denotes |
These |
T1194 |
382-390 |
NNS |
denotes |
findings |
T1195 |
391-398 |
VBP |
denotes |
provide |
T1196 |
399-402 |
DT |
denotes |
the |
T1197 |
403-414 |
NN |
denotes |
possibility |
T1198 |
415-419 |
IN |
denotes |
that |
T1199 |
429-433 |
VB |
denotes |
play |
T1200 |
420-422 |
NN |
denotes |
mr |
T1201 |
423-424 |
NN |
denotes |
s |
T1202 |
422-423 |
HYPH |
denotes |
- |
T1203 |
425-428 |
MD |
denotes |
may |
T1204 |
434-435 |
DT |
denotes |
a |
T1205 |
445-449 |
NN |
denotes |
role |
T1206 |
436-444 |
JJ |
denotes |
critical |
T1207 |
450-452 |
IN |
denotes |
by |
T1208 |
453-463 |
VBG |
denotes |
regulating |
T1209 |
464-468 |
NN |
denotes |
gene |
T1210 |
469-479 |
NN |
denotes |
expression |
T1211 |
480-482 |
IN |
denotes |
in |
T1212 |
483-496 |
NN |
denotes |
photoreceptor |
T1213 |
497-508 |
NN |
denotes |
development |
T1214 |
508-509 |
. |
denotes |
. |
T1215 |
509-678 |
sentence |
denotes |
mr-s is preferentially expressed in the photoreceptors at postnatal day 3–6 (P3-6), when photoreceptors undergo terminal differentiation, and in the adult pineal gland. |
T1216 |
510-512 |
NN |
denotes |
mr |
T1217 |
513-514 |
NN |
denotes |
s |
T1218 |
512-513 |
HYPH |
denotes |
- |
T1219 |
533-542 |
VBN |
denotes |
expressed |
T1220 |
515-517 |
VBZ |
denotes |
is |
T1221 |
518-532 |
RB |
denotes |
preferentially |
T1222 |
543-545 |
IN |
denotes |
in |
T1223 |
546-549 |
DT |
denotes |
the |
T1224 |
550-564 |
NNS |
denotes |
photoreceptors |
T1225 |
565-567 |
IN |
denotes |
at |
T1226 |
568-577 |
JJ |
denotes |
postnatal |
T1227 |
582-583 |
CD |
denotes |
3 |
T1228 |
578-581 |
NN |
denotes |
day |
T1229 |
583-584 |
SYM |
denotes |
– |
T1230 |
584-585 |
CD |
denotes |
6 |
T1231 |
586-587 |
-LRB- |
denotes |
( |
T1232 |
587-589 |
NN |
denotes |
P3 |
T1233 |
589-590 |
SYM |
denotes |
- |
T1234 |
590-591 |
CD |
denotes |
6 |
T1235 |
591-592 |
-RRB- |
denotes |
) |
T1236 |
592-594 |
, |
denotes |
, |
T1237 |
594-598 |
WRB |
denotes |
when |
T1238 |
614-621 |
VBP |
denotes |
undergo |
T1239 |
599-613 |
NNS |
denotes |
photoreceptors |
T1240 |
622-630 |
JJ |
denotes |
terminal |
T1241 |
631-646 |
NN |
denotes |
differentiation |
T1242 |
646-648 |
, |
denotes |
, |
T1243 |
648-651 |
CC |
denotes |
and |
T1244 |
652-654 |
IN |
denotes |
in |
T1245 |
655-658 |
DT |
denotes |
the |
T1246 |
672-677 |
NN |
denotes |
gland |
T1247 |
659-664 |
JJ |
denotes |
adult |
T1248 |
665-671 |
JJ |
denotes |
pineal |
T1249 |
677-678 |
. |
denotes |
. |
T1250 |
678-763 |
sentence |
denotes |
Transcription of mr-s is directly regulated by the cone-rod homeodomain protein Crx. |
T1251 |
679-692 |
NN |
denotes |
Transcription |
T1252 |
713-722 |
VBN |
denotes |
regulated |
T1253 |
693-695 |
IN |
denotes |
of |
T1254 |
696-698 |
NN |
denotes |
mr |
T1255 |
699-700 |
NN |
denotes |
s |
T1256 |
698-699 |
HYPH |
denotes |
- |
T1257 |
701-703 |
VBZ |
denotes |
is |
T1258 |
704-712 |
RB |
denotes |
directly |
T1259 |
723-725 |
IN |
denotes |
by |
T1260 |
726-729 |
DT |
denotes |
the |
T1261 |
751-758 |
NN |
denotes |
protein |
T1262 |
730-734 |
NN |
denotes |
cone |
T1263 |
735-738 |
NN |
denotes |
rod |
T1264 |
734-735 |
HYPH |
denotes |
- |
T1265 |
739-750 |
NN |
denotes |
homeodomain |
T1266 |
759-762 |
NN |
denotes |
Crx |
T1267 |
762-763 |
. |
denotes |
. |
T1268 |
763-897 |
sentence |
denotes |
Immunoprecipitation assay showed that the mr-s protein self-associates mainly through the SAM domain-containing region as well as ph. |
T1269 |
764-783 |
NN |
denotes |
Immunoprecipitation |
T1270 |
784-789 |
NN |
denotes |
assay |
T1271 |
790-796 |
VBD |
denotes |
showed |
T1272 |
797-801 |
IN |
denotes |
that |
T1273 |
824-834 |
VBZ |
denotes |
associates |
T1274 |
802-805 |
DT |
denotes |
the |
T1275 |
811-818 |
NN |
denotes |
protein |
T1276 |
806-808 |
NN |
denotes |
mr |
T1277 |
809-810 |
NN |
denotes |
s |
T1278 |
808-809 |
HYPH |
denotes |
- |
T1279 |
819-823 |
NN |
denotes |
self |
T1280 |
823-824 |
HYPH |
denotes |
- |
T1281 |
835-841 |
RB |
denotes |
mainly |
T1282 |
842-849 |
IN |
denotes |
through |
T1283 |
850-853 |
DT |
denotes |
the |
T1284 |
876-882 |
NN |
denotes |
region |
T1285 |
854-857 |
NN |
denotes |
SAM |
T1286 |
858-864 |
NN |
denotes |
domain |
T1287 |
865-875 |
VBG |
denotes |
containing |
T1288 |
864-865 |
HYPH |
denotes |
- |
T1289 |
883-885 |
RB |
denotes |
as |
T1290 |
891-893 |
IN |
denotes |
as |
T1291 |
886-890 |
RB |
denotes |
well |
T1292 |
894-896 |
NN |
denotes |
ph |
T1293 |
896-897 |
. |
denotes |
. |
T1294 |
897-992 |
sentence |
denotes |
The mr-s protein localizes mainly in the nucleus, when mr-s is overexpressed in HEK293T cells. |
T1295 |
898-901 |
DT |
denotes |
The |
T1296 |
907-914 |
NN |
denotes |
protein |
T1297 |
902-904 |
NN |
denotes |
mr |
T1298 |
905-906 |
NN |
denotes |
s |
T1299 |
904-905 |
HYPH |
denotes |
- |
T1300 |
915-924 |
VBZ |
denotes |
localizes |
T1301 |
925-931 |
RB |
denotes |
mainly |
T1302 |
932-934 |
IN |
denotes |
in |
T1303 |
935-938 |
DT |
denotes |
the |
T1304 |
939-946 |
NN |
denotes |
nucleus |
T1305 |
946-948 |
, |
denotes |
, |
T1306 |
948-952 |
WRB |
denotes |
when |
T1307 |
961-974 |
VBN |
denotes |
overexpressed |
T1308 |
953-955 |
NN |
denotes |
mr |
T1309 |
956-957 |
NN |
denotes |
s |
T1310 |
955-956 |
HYPH |
denotes |
- |
T1311 |
958-960 |
VBZ |
denotes |
is |
T1312 |
975-977 |
IN |
denotes |
in |
T1313 |
978-985 |
NN |
denotes |
HEK293T |
T1314 |
986-991 |
NNS |
denotes |
cells |
T1315 |
991-992 |
. |
denotes |
. |
T1316 |
992-1130 |
sentence |
denotes |
Moreover, in the luciferase assays, we found that mr-s protein fused to GAL4 DNA-binding domain functions as a transcriptional repressor. |
T1317 |
993-1001 |
RB |
denotes |
Moreover |
T1318 |
1032-1037 |
VBD |
denotes |
found |
T1319 |
1001-1003 |
, |
denotes |
, |
T1320 |
1003-1005 |
IN |
denotes |
in |
T1321 |
1006-1009 |
DT |
denotes |
the |
T1322 |
1021-1027 |
NNS |
denotes |
assays |
T1323 |
1010-1020 |
NN |
denotes |
luciferase |
T1324 |
1027-1029 |
, |
denotes |
, |
T1325 |
1029-1031 |
PRP |
denotes |
we |
T1326 |
1038-1042 |
IN |
denotes |
that |
T1327 |
1089-1098 |
VBZ |
denotes |
functions |
T1328 |
1043-1045 |
NN |
denotes |
mr |
T1329 |
1046-1047 |
NN |
denotes |
s |
T1330 |
1045-1046 |
HYPH |
denotes |
- |
T1331 |
1048-1055 |
NN |
denotes |
protein |
T1332 |
1056-1061 |
VBN |
denotes |
fused |
T1333 |
1062-1064 |
IN |
denotes |
to |
T1334 |
1065-1069 |
NN |
denotes |
GAL4 |
T1335 |
1082-1088 |
NN |
denotes |
domain |
T1336 |
1070-1073 |
NN |
denotes |
DNA |
T1337 |
1074-1081 |
VBG |
denotes |
binding |
T1338 |
1073-1074 |
HYPH |
denotes |
- |
T1339 |
1099-1101 |
IN |
denotes |
as |
T1340 |
1102-1103 |
DT |
denotes |
a |
T1341 |
1120-1129 |
NN |
denotes |
repressor |
T1342 |
1104-1119 |
JJ |
denotes |
transcriptional |
T1343 |
1129-1130 |
. |
denotes |
. |
T1344 |
1130-1271 |
sentence |
denotes |
We revealed that the repression activity of mr-s is not due to a homophilic interaction through its SAM domain but to the C-terminal region. |
T1345 |
1131-1133 |
PRP |
denotes |
We |
T1346 |
1134-1142 |
VBD |
denotes |
revealed |
T1347 |
1143-1147 |
IN |
denotes |
that |
T1348 |
1180-1182 |
VBZ |
denotes |
is |
T1349 |
1148-1151 |
DT |
denotes |
the |
T1350 |
1163-1171 |
NN |
denotes |
activity |
T1351 |
1152-1162 |
NN |
denotes |
repression |
T1352 |
1172-1174 |
IN |
denotes |
of |
T1353 |
1175-1177 |
NN |
denotes |
mr |
T1354 |
1178-1179 |
NN |
denotes |
s |
T1355 |
1177-1178 |
HYPH |
denotes |
- |
T1356 |
1183-1186 |
RB |
denotes |
not |
T1357 |
1187-1190 |
IN |
denotes |
due |
T1358 |
1191-1193 |
IN |
denotes |
to |
T1359 |
1194-1195 |
DT |
denotes |
a |
T1360 |
1207-1218 |
NN |
denotes |
interaction |
T1361 |
1196-1206 |
JJ |
denotes |
homophilic |
T1362 |
1219-1226 |
IN |
denotes |
through |
T1363 |
1227-1230 |
PRP$ |
denotes |
its |
T1364 |
1235-1241 |
NN |
denotes |
domain |
T1365 |
1231-1234 |
NN |
denotes |
SAM |
T1366 |
1242-1245 |
CC |
denotes |
but |
T1367 |
1246-1248 |
IN |
denotes |
to |
T1368 |
1249-1252 |
DT |
denotes |
the |
T1369 |
1264-1270 |
NN |
denotes |
region |
T1370 |
1253-1254 |
NN |
denotes |
C |
T1371 |
1255-1263 |
JJ |
denotes |
terminal |
T1372 |
1254-1255 |
HYPH |
denotes |
- |
T1373 |
1270-1271 |
. |
denotes |
. |
R112 |
T1128 |
T1130 |
nsubjpass |
s,conserved |
R113 |
T1129 |
T1128 |
punct |
-,s |
R123 |
T1140 |
T1138 |
relcl |
conserved,organisms |
R124 |
T1141 |
T1139 |
pobj |
which,through |
R125 |
T1142 |
T1143 |
det |
the,mechanism |
R126 |
T1143 |
T1140 |
nsubjpass |
mechanism,conserved |
R127 |
T1144 |
T1143 |
prep |
of,mechanism |
R128 |
T1145 |
T1146 |
compound |
photoreceptor,development |
R129 |
T1146 |
T1144 |
pobj |
development,of |
R130 |
T1147 |
T1140 |
auxpass |
is,conserved |
R131 |
T1148 |
T1140 |
advmod |
also,conserved |
R132 |
T1149 |
T1140 |
advmod |
highly,conserved |
R137 |
T1156 |
T1154 |
ccomp |
related,suggests |
R138 |
T1157 |
T1158 |
det |
the,domain |
R140 |
T1159 |
T1158 |
compound |
SAM,domain |
R141 |
T1160 |
T1158 |
prep |
of,domain |
R142 |
T1161 |
T1162 |
compound |
mr,s |
R144 |
T1163 |
T1162 |
punct |
-,s |
R145 |
T1164 |
T1156 |
auxpass |
is,related |
R146 |
T1165 |
T1166 |
advmod |
most,closely |
R147 |
T1166 |
T1156 |
advmod |
closely,related |
R150 |
T1169 |
T1167 |
pobj |
ortholog,to |
R151 |
T1170 |
T1169 |
nmod |
mouse,ortholog |
R152 |
T1171 |
T1169 |
nmod |
polyhomeotic,ortholog |
R153 |
T1172 |
T1173 |
punct |
(,ph |
R154 |
T1173 |
T1171 |
parataxis |
ph,polyhomeotic |
R155 |
T1174 |
T1173 |
punct |
),ph |
R158 |
T1177 |
T1169 |
appos |
Rae28,ortholog |
R159 |
T1178 |
T1177 |
punct |
/,Rae28 |
R162 |
T1181 |
T1169 |
relcl |
known,ortholog |
R163 |
T1182 |
T1181 |
auxpass |
is,known |
R166 |
T1185 |
T1183 |
pobj |
molecule,as |
R167 |
T1186 |
T1185 |
amod |
epigenetic,molecule |
R178 |
T1199 |
T1197 |
acl |
play,possibility |
R179 |
T1200 |
T1201 |
compound |
mr,s |
R181 |
T1202 |
T1201 |
punct |
-,s |
R182 |
T1203 |
T1199 |
aux |
may,play |
R184 |
T1205 |
T1199 |
dobj |
role,play |
R185 |
T1206 |
T1205 |
amod |
critical,role |
R195 |
T1217 |
T1219 |
nsubjpass |
s,expressed |
R196 |
T1218 |
T1217 |
punct |
-,s |
R204 |
T1227 |
T1225 |
pobj |
3,at |
R205 |
T1228 |
T1227 |
nmod |
day,3 |
R215 |
T1238 |
T1227 |
advcl |
undergo,3 |
R216 |
T1239 |
T1238 |
nsubj |
photoreceptors,undergo |
R223 |
T1246 |
T1244 |
pobj |
gland,in |
R224 |
T1247 |
T1246 |
amod |
adult,gland |
R225 |
T1248 |
T1246 |
amod |
pineal,gland |
R230 |
T1255 |
T1253 |
pobj |
s,of |
R231 |
T1256 |
T1255 |
punct |
-,s |
R236 |
T1261 |
T1259 |
pobj |
protein,by |
R237 |
T1262 |
T1263 |
compound |
cone,rod |
R239 |
T1264 |
T1263 |
punct |
-,rod |
R240 |
T1265 |
T1261 |
compound |
homeodomain,protein |
R246 |
T1273 |
T1271 |
ccomp |
associates,showed |
R247 |
T1274 |
T1275 |
det |
the,protein |
R248 |
T1275 |
T1273 |
nsubj |
protein,associates |
R249 |
T1276 |
T1277 |
compound |
mr,s |
R250 |
T1277 |
T1275 |
compound |
s,protein |
R251 |
T1278 |
T1277 |
punct |
-,s |
R252 |
T1279 |
T1273 |
dep |
self,associates |
R253 |
T1280 |
T1273 |
punct |
-,associates |
R257 |
T1284 |
T1282 |
pobj |
region,through |
R258 |
T1285 |
T1286 |
compound |
SAM,domain |
R259 |
T1286 |
T1287 |
npadvmod |
domain,containing |
R261 |
T1288 |
T1287 |
punct |
-,containing |
R263 |
T1290 |
T1284 |
cc |
as,region |
R264 |
T1291 |
T1290 |
advmod |
well,as |
R268 |
T1296 |
T1300 |
nsubj |
protein,localizes |
R269 |
T1297 |
T1298 |
compound |
mr,s |
R271 |
T1299 |
T1298 |
punct |
-,s |
R278 |
T1307 |
T1300 |
advcl |
overexpressed,localizes |
R279 |
T1308 |
T1309 |
compound |
mr,s |
R281 |
T1310 |
T1309 |
punct |
-,s |
R282 |
T1311 |
T1307 |
auxpass |
is,overexpressed |
R291 |
T1322 |
T1320 |
pobj |
assays,in |
R292 |
T1323 |
T1322 |
compound |
luciferase,assays |
R296 |
T1327 |
T1318 |
ccomp |
functions,found |
R297 |
T1328 |
T1329 |
compound |
mr,s |
R299 |
T1330 |
T1329 |
punct |
-,s |
R300 |
T1331 |
T1327 |
nsubj |
protein,functions |
R301 |
T1332 |
T1331 |
acl |
fused,protein |
R302 |
T1333 |
T1332 |
prep |
to,fused |
R303 |
T1334 |
T1335 |
nmod |
GAL4,domain |
R304 |
T1335 |
T1333 |
pobj |
domain,to |
R305 |
T1336 |
T1337 |
npadvmod |
DNA,binding |
R306 |
T1337 |
T1335 |
amod |
binding,domain |
R307 |
T1338 |
T1337 |
punct |
-,binding |
R310 |
T1341 |
T1339 |
pobj |
repressor,as |
R311 |
T1342 |
T1341 |
amod |
transcriptional,repressor |
R315 |
T1348 |
T1346 |
ccomp |
is,revealed |
R316 |
T1349 |
T1350 |
det |
the,activity |
R318 |
T1351 |
T1350 |
compound |
repression,activity |
R319 |
T1352 |
T1350 |
prep |
of,activity |
R320 |
T1353 |
T1354 |
compound |
mr,s |
R322 |
T1355 |
T1354 |
punct |
-,s |
R327 |
T1360 |
T1358 |
pobj |
interaction,to |
R328 |
T1361 |
T1360 |
amod |
homophilic,interaction |
R331 |
T1364 |
T1362 |
pobj |
domain,through |
R332 |
T1365 |
T1364 |
compound |
SAM,domain |
R336 |
T1369 |
T1367 |
pobj |
region,to |
R337 |
T1370 |
T1371 |
npadvmod |
C,terminal |
R339 |
T1372 |
T1371 |
punct |
-,terminal |
R111 |
T1127 |
T1128 |
compound |
mr,s |
R114 |
T1131 |
T1130 |
auxpass |
is,conserved |
R115 |
T1132 |
T1130 |
advmod |
evolutionarily,conserved |
R116 |
T1133 |
T1130 |
prep |
from,conserved |
R117 |
T1134 |
T1133 |
pobj |
zebrafish,from |
R118 |
T1135 |
T1133 |
prep |
through,from |
R119 |
T1136 |
T1135 |
pobj |
human,through |
R120 |
T1137 |
T1130 |
punct |
", ",conserved |
R121 |
T1138 |
T1130 |
npadvmod |
organisms,conserved |
R122 |
T1139 |
T1140 |
prep |
through,conserved |
R133 |
T1150 |
T1130 |
punct |
.,conserved |
R134 |
T1152 |
T1153 |
amod |
Phylogenetic,analysis |
R135 |
T1153 |
T1154 |
nsubj |
analysis,suggests |
R136 |
T1155 |
T1156 |
mark |
that,related |
R139 |
T1158 |
T1156 |
nsubjpass |
domain,related |
R143 |
T1162 |
T1160 |
pobj |
s,of |
R148 |
T1167 |
T1156 |
prep |
to,related |
R149 |
T1168 |
T1169 |
det |
a,ortholog |
R156 |
T1175 |
T1169 |
punct |
", ",ortholog |
R157 |
T1176 |
T1177 |
compound |
Mph1,Rae28 |
R160 |
T1179 |
T1169 |
punct |
", ",ortholog |
R161 |
T1180 |
T1181 |
dep |
which,known |
R164 |
T1183 |
T1181 |
prep |
as,known |
R165 |
T1184 |
T1185 |
det |
an,molecule |
R168 |
T1187 |
T1185 |
acl |
involved,molecule |
R169 |
T1188 |
T1187 |
prep |
in,involved |
R170 |
T1189 |
T1190 |
compound |
chromatin,modifications |
R171 |
T1190 |
T1188 |
pobj |
modifications,in |
R172 |
T1191 |
T1154 |
punct |
.,suggests |
R173 |
T1193 |
T1194 |
det |
These,findings |
R174 |
T1194 |
T1195 |
nsubj |
findings,provide |
R175 |
T1196 |
T1197 |
det |
the,possibility |
R176 |
T1197 |
T1195 |
dobj |
possibility,provide |
R177 |
T1198 |
T1199 |
mark |
that,play |
R180 |
T1201 |
T1199 |
nsubj |
s,play |
R183 |
T1204 |
T1205 |
det |
a,role |
R186 |
T1207 |
T1199 |
prep |
by,play |
R187 |
T1208 |
T1207 |
pcomp |
regulating,by |
R188 |
T1209 |
T1210 |
compound |
gene,expression |
R189 |
T1210 |
T1208 |
dobj |
expression,regulating |
R190 |
T1211 |
T1208 |
prep |
in,regulating |
R191 |
T1212 |
T1213 |
compound |
photoreceptor,development |
R192 |
T1213 |
T1211 |
pobj |
development,in |
R193 |
T1214 |
T1195 |
punct |
.,provide |
R194 |
T1216 |
T1217 |
compound |
mr,s |
R197 |
T1220 |
T1219 |
auxpass |
is,expressed |
R198 |
T1221 |
T1219 |
advmod |
preferentially,expressed |
R199 |
T1222 |
T1219 |
prep |
in,expressed |
R200 |
T1223 |
T1224 |
det |
the,photoreceptors |
R201 |
T1224 |
T1222 |
pobj |
photoreceptors,in |
R202 |
T1225 |
T1219 |
prep |
at,expressed |
R203 |
T1226 |
T1227 |
amod |
postnatal,3 |
R206 |
T1229 |
T1230 |
punct |
–,6 |
R207 |
T1230 |
T1227 |
prep |
6,3 |
R208 |
T1231 |
T1232 |
punct |
(,P3 |
R209 |
T1232 |
T1227 |
parataxis |
P3,3 |
R210 |
T1233 |
T1234 |
punct |
-,6 |
R211 |
T1234 |
T1232 |
prep |
6,P3 |
R212 |
T1235 |
T1232 |
punct |
),P3 |
R213 |
T1236 |
T1227 |
punct |
", ",3 |
R214 |
T1237 |
T1238 |
advmod |
when,undergo |
R217 |
T1240 |
T1241 |
amod |
terminal,differentiation |
R218 |
T1241 |
T1238 |
dobj |
differentiation,undergo |
R219 |
T1242 |
T1219 |
punct |
", ",expressed |
R220 |
T1243 |
T1244 |
cc |
and,in |
R221 |
T1244 |
T1219 |
prep |
in,expressed |
R222 |
T1245 |
T1246 |
det |
the,gland |
R226 |
T1249 |
T1219 |
punct |
.,expressed |
R227 |
T1251 |
T1252 |
nsubjpass |
Transcription,regulated |
R228 |
T1253 |
T1251 |
prep |
of,Transcription |
R229 |
T1254 |
T1255 |
compound |
mr,s |
R232 |
T1257 |
T1252 |
auxpass |
is,regulated |
R233 |
T1258 |
T1252 |
advmod |
directly,regulated |
R234 |
T1259 |
T1252 |
agent |
by,regulated |
R235 |
T1260 |
T1261 |
det |
the,protein |
R238 |
T1263 |
T1261 |
compound |
rod,protein |
R241 |
T1266 |
T1261 |
appos |
Crx,protein |
R242 |
T1267 |
T1252 |
punct |
.,regulated |
R243 |
T1269 |
T1270 |
compound |
Immunoprecipitation,assay |
R244 |
T1270 |
T1271 |
nsubj |
assay,showed |
R245 |
T1272 |
T1273 |
mark |
that,associates |
R254 |
T1281 |
T1282 |
advmod |
mainly,through |
R255 |
T1282 |
T1273 |
prep |
through,associates |
R256 |
T1283 |
T1284 |
det |
the,region |
R260 |
T1287 |
T1284 |
amod |
containing,region |
R262 |
T1289 |
T1290 |
advmod |
as,as |
R265 |
T1292 |
T1284 |
conj |
ph,region |
R266 |
T1293 |
T1271 |
punct |
.,showed |
R267 |
T1295 |
T1296 |
det |
The,protein |
R270 |
T1298 |
T1296 |
compound |
s,protein |
R272 |
T1301 |
T1302 |
advmod |
mainly,in |
R273 |
T1302 |
T1300 |
prep |
in,localizes |
R274 |
T1303 |
T1304 |
det |
the,nucleus |
R275 |
T1304 |
T1302 |
pobj |
nucleus,in |
R276 |
T1305 |
T1300 |
punct |
", ",localizes |
R277 |
T1306 |
T1307 |
advmod |
when,overexpressed |
R280 |
T1309 |
T1307 |
nsubjpass |
s,overexpressed |
R283 |
T1312 |
T1307 |
prep |
in,overexpressed |
R284 |
T1313 |
T1314 |
compound |
HEK293T,cells |
R285 |
T1314 |
T1312 |
pobj |
cells,in |
R286 |
T1315 |
T1300 |
punct |
.,localizes |
R287 |
T1317 |
T1318 |
advmod |
Moreover,found |
R288 |
T1319 |
T1318 |
punct |
", ",found |
R289 |
T1320 |
T1318 |
prep |
in,found |
R290 |
T1321 |
T1322 |
det |
the,assays |
R293 |
T1324 |
T1318 |
punct |
", ",found |
R294 |
T1325 |
T1318 |
nsubj |
we,found |
R295 |
T1326 |
T1327 |
mark |
that,functions |
R298 |
T1329 |
T1331 |
compound |
s,protein |
R308 |
T1339 |
T1327 |
prep |
as,functions |
R309 |
T1340 |
T1341 |
det |
a,repressor |
R312 |
T1343 |
T1318 |
punct |
.,found |
R313 |
T1345 |
T1346 |
nsubj |
We,revealed |
R314 |
T1347 |
T1348 |
mark |
that,is |
R317 |
T1350 |
T1348 |
nsubj |
activity,is |
R321 |
T1354 |
T1352 |
pobj |
s,of |
R323 |
T1356 |
T1348 |
neg |
not,is |
R324 |
T1357 |
T1348 |
prep |
due,is |
R325 |
T1358 |
T1357 |
prep |
to,due |
R326 |
T1359 |
T1360 |
det |
a,interaction |
R329 |
T1362 |
T1360 |
prep |
through,interaction |
R330 |
T1363 |
T1364 |
poss |
its,domain |
R333 |
T1366 |
T1358 |
cc |
but,to |
R334 |
T1367 |
T1358 |
conj |
to,to |
R335 |
T1368 |
T1369 |
det |
the,region |
R338 |
T1371 |
T1369 |
amod |
terminal,region |
R340 |
T1373 |
T1346 |
punct |
.,revealed |