PMC:1435744 / 4727-4982 JSONTXT

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T3477","span":{"begin":14,"end":23},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T3478","span":{"begin":27,"end":32},"obj":"NCBITaxon:9606"},{"id":"T3479","span":{"begin":33,"end":36},"obj":"PR_EXT:000005904"},{"id":"T3480","span":{"begin":97,"end":110},"obj":"CL:0000210"},{"id":"T3481","span":{"begin":121,"end":130},"obj":"GO:0030849"},{"id":"T3482","span":{"begin":140,"end":144},"obj":"CL:0000573"},{"id":"T3483","span":{"begin":145,"end":148},"obj":"CL:0000604"},{"id":"T3484","span":{"begin":162,"end":171},"obj":"GO:0030849"}],"text":" In addition, mutations of human CRX have been demonstrated to be associated with three types of photoreceptor diseases: autosomal dominant cone-rod dystrophy 2, autosomal dominant-type retinitis pigmentosa, and Leber's congenital amaurosis (LCA) [11-14]."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T3283","span":{"begin":27,"end":32},"obj":"NCBITaxon:9606"},{"id":"T3284","span":{"begin":33,"end":36},"obj":"PR:000005904"},{"id":"T3285","span":{"begin":97,"end":110},"obj":"CL:0000210"},{"id":"T3286","span":{"begin":121,"end":130},"obj":"GO:0030849"},{"id":"T3287","span":{"begin":140,"end":144},"obj":"CL:0000573"},{"id":"T3288","span":{"begin":145,"end":148},"obj":"CL:0000604"},{"id":"T3289","span":{"begin":162,"end":171},"obj":"GO:0030849"}],"text":" In addition, mutations of human CRX have been demonstrated to be associated with three types of photoreceptor diseases: autosomal dominant cone-rod dystrophy 2, autosomal dominant-type retinitis pigmentosa, and Leber's congenital amaurosis (LCA) [11-14]."}

{"project":"craft-sa-dev","denotations":[{"id":"T4046","span":{"begin":0,"end":255},"obj":"sentence"},{"id":"T4047","span":{"begin":1,"end":3},"obj":"IN"},{"id":"T4048","span":{"begin":47,"end":59},"obj":"VBN"},{"id":"T4049","span":{"begin":4,"end":12},"obj":"NN"},{"id":"T4050","span":{"begin":12,"end":14},"obj":","},{"id":"T4051","span":{"begin":14,"end":23},"obj":"NNS"},{"id":"T4052","span":{"begin":24,"end":26},"obj":"IN"},{"id":"T4053","span":{"begin":27,"end":32},"obj":"JJ"},{"id":"T4054","span":{"begin":33,"end":36},"obj":"NN"},{"id":"T4055","span":{"begin":37,"end":41},"obj":"VBP"},{"id":"T4056","span":{"begin":42,"end":46},"obj":"VBN"},{"id":"T4057","span":{"begin":60,"end":62},"obj":"TO"},{"id":"T4058","span":{"begin":66,"end":76},"obj":"VBN"},{"id":"T4059","span":{"begin":63,"end":65},"obj":"VB"},{"id":"T4060","span":{"begin":77,"end":81},"obj":"IN"},{"id":"T4061","span":{"begin":82,"end":87},"obj":"CD"},{"id":"T4062","span":{"begin":88,"end":93},"obj":"NNS"},{"id":"T4063","span":{"begin":94,"end":96},"obj":"IN"},{"id":"T4064","span":{"begin":97,"end":110},"obj":"NN"},{"id":"T4065","span":{"begin":111,"end":119},"obj":"NNS"},{"id":"T4066","span":{"begin":119,"end":121},"obj":":"},{"id":"T4067","span":{"begin":121,"end":130},"obj":"JJ"},{"id":"T4068","span":{"begin":131,"end":139},"obj":"JJ"},{"id":"T4069","span":{"begin":149,"end":158},"obj":"NN"},{"id":"T4070","span":{"begin":140,"end":144},"obj":"NN"},{"id":"T4071","span":{"begin":145,"end":148},"obj":"NN"},{"id":"T4072","span":{"begin":144,"end":145},"obj":"HYPH"},{"id":"T4073","span":{"begin":159,"end":160},"obj":"CD"},{"id":"T4074","span":{"begin":160,"end":162},"obj":","},{"id":"T4075","span":{"begin":162,"end":171},"obj":"JJ"},{"id":"T4076","span":{"begin":172,"end":180},"obj":"JJ"},{"id":"T4077","span":{"begin":181,"end":185},"obj":"NN"},{"id":"T4078","span":{"begin":180,"end":181},"obj":"HYPH"},{"id":"T4079","span":{"begin":196,"end":206},"obj":"NN"},{"id":"T4080","span":{"begin":186,"end":195},"obj":"NN"},{"id":"T4081","span":{"begin":206,"end":208},"obj":","},{"id":"T4082","span":{"begin":208,"end":211},"obj":"CC"},{"id":"T4083","span":{"begin":212,"end":217},"obj":"NNP"},{"id":"T4084","span":{"begin":231,"end":240},"obj":"NN"},{"id":"T4085","span":{"begin":217,"end":219},"obj":"POS"},{"id":"T4086","span":{"begin":220,"end":230},"obj":"JJ"},{"id":"T4087","span":{"begin":241,"end":242},"obj":"-LRB-"},{"id":"T4088","span":{"begin":242,"end":245},"obj":"NN"},{"id":"T4089","span":{"begin":245,"end":246},"obj":"-RRB-"},{"id":"T4090","span":{"begin":247,"end":248},"obj":"-LRB-"},{"id":"T4091","span":{"begin":248,"end":250},"obj":"CD"},{"id":"T4092","span":{"begin":250,"end":251},"obj":"SYM"},{"id":"T4093","span":{"begin":251,"end":253},"obj":"CD"},{"id":"T4094","span":{"begin":253,"end":254},"obj":"-RRB-"},{"id":"T4095","span":{"begin":254,"end":255},"obj":"."}],"relations":[{"id":"R788","pred":"amod","subj":"T4053","obj":"T4054"},{"id":"R794","pred":"pobj","subj":"T4054","obj":"T4052"},{"id":"R797","pred":"aux","subj":"T4055","obj":"T4048"},{"id":"R800","pred":"auxpass","subj":"T4056","obj":"T4048"},{"id":"R805","pred":"aux","subj":"T4057","obj":"T4058"},{"id":"R808","pred":"xcomp","subj":"T4058","obj":"T4048"},{"id":"R816","pred":"auxpass","subj":"T4059","obj":"T4058"},{"id":"R820","pred":"prep","subj":"T4060","obj":"T4058"},{"id":"R824","pred":"nummod","subj":"T4061","obj":"T4062"},{"id":"R828","pred":"pobj","subj":"T4062","obj":"T4060"},{"id":"R830","pred":"prep","subj":"T4063","obj":"T4062"},{"id":"R831","pred":"prep","subj":"T4047","obj":"T4048"},{"id":"R832","pred":"pobj","subj":"T4049","obj":"T4047"},{"id":"R833","pred":"punct","subj":"T4050","obj":"T4048"},{"id":"R834","pred":"compound","subj":"T4064","obj":"T4065"},{"id":"R835","pred":"nsubjpass","subj":"T4051","obj":"T4048"},{"id":"R836","pred":"prep","subj":"T4052","obj":"T4051"},{"id":"R837","pred":"pobj","subj":"T4065","obj":"T4063"},{"id":"R838","pred":"punct","subj":"T4066","obj":"T4062"},{"id":"R839","pred":"amod","subj":"T4067","obj":"T4068"},{"id":"R840","pred":"amod","subj":"T4068","obj":"T4069"},{"id":"R841","pred":"appos","subj":"T4069","obj":"T4062"},{"id":"R844","pred":"compound","subj":"T4070","obj":"T4071"},{"id":"R847","pred":"compound","subj":"T4071","obj":"T4069"},{"id":"R850","pred":"punct","subj":"T4072","obj":"T4071"},{"id":"R854","pred":"nummod","subj":"T4073","obj":"T4069"},{"id":"R856","pred":"punct","subj":"T4074","obj":"T4069"},{"id":"R859","pred":"amod","subj":"T4075","obj":"T4076"},{"id":"R866","pred":"amod","subj":"T4076","obj":"T4077"},{"id":"R871","pred":"compound","subj":"T4077","obj":"T4079"},{"id":"R875","pred":"punct","subj":"T4078","obj":"T4077"},{"id":"R878","pred":"conj","subj":"T4079","obj":"T4069"},{"id":"R883","pred":"compound","subj":"T4080","obj":"T4079"},{"id":"R886","pred":"punct","subj":"T4081","obj":"T4079"},{"id":"R890","pred":"cc","subj":"T4082","obj":"T4079"},{"id":"R894","pred":"poss","subj":"T4083","obj":"T4084"},{"id":"R898","pred":"conj","subj":"T4084","obj":"T4079"},{"id":"R901","pred":"case","subj":"T4085","obj":"T4083"},{"id":"R905","pred":"amod","subj":"T4086","obj":"T4084"},{"id":"R907","pred":"punct","subj":"T4087","obj":"T4084"},{"id":"R912","pred":"appos","subj":"T4088","obj":"T4084"},{"id":"R919","pred":"punct","subj":"T4089","obj":"T4048"},{"id":"R923","pred":"punct","subj":"T4090","obj":"T4091"},{"id":"R927","pred":"parataxis","subj":"T4091","obj":"T4048"},{"id":"R931","pred":"punct","subj":"T4092","obj":"T4093"},{"id":"R935","pred":"prep","subj":"T4093","obj":"T4091"},{"id":"R938","pred":"punct","subj":"T4094","obj":"T4091"},{"id":"R943","pred":"punct","subj":"T4095","obj":"T4048"}],"text":" In addition, mutations of human CRX have been demonstrated to be associated with three types of photoreceptor diseases: autosomal dominant cone-rod dystrophy 2, autosomal dominant-type retinitis pigmentosa, and Leber's congenital amaurosis (LCA) [11-14]."}