Id |
Subject |
Object |
Predicate |
Lexical cue |
T2208 |
11-20 |
JJ |
denotes |
Embryonic |
T2209 |
21-25 |
NN |
denotes |
stem |
T2210 |
31-36 |
NNS |
denotes |
cells |
T2211 |
26-27 |
-LRB- |
denotes |
( |
T2212 |
27-29 |
NN |
denotes |
ES |
T2213 |
29-30 |
-RRB- |
denotes |
) |
T2214 |
48-55 |
VBN |
denotes |
derived |
T2215 |
37-41 |
VBD |
denotes |
were |
T2216 |
42-47 |
RB |
denotes |
first |
T2217 |
56-60 |
IN |
denotes |
from |
T2218 |
61-64 |
DT |
denotes |
the |
T2219 |
65-76 |
NNS |
denotes |
blastocysts |
T2220 |
77-79 |
IN |
denotes |
of |
T2221 |
80-84 |
NNS |
denotes |
mice |
T2222 |
85-87 |
IN |
denotes |
in |
T2223 |
88-92 |
CD |
denotes |
1981 |
T2224 |
93-94 |
-LRB- |
denotes |
[ |
T2225 |
96-97 |
CD |
denotes |
2 |
T2226 |
94-95 |
CD |
denotes |
1 |
T2227 |
95-96 |
, |
denotes |
, |
T2228 |
97-98 |
-RRB- |
denotes |
] |
T2229 |
99-102 |
CC |
denotes |
and |
T2230 |
103-109 |
NNS |
denotes |
humans |
T2231 |
110-112 |
IN |
denotes |
in |
T2232 |
113-117 |
CD |
denotes |
1998 |
T2233 |
118-119 |
-LRB- |
denotes |
[ |
T2234 |
119-120 |
CD |
denotes |
3 |
T2235 |
120-121 |
-RRB- |
denotes |
] |
T2236 |
121-122 |
. |
denotes |
. |
T2237 |
122-292 |
sentence |
denotes |
ES cells have two important properties: theability to maintain pluripotency, which is the ability to differentiate into a wide variety of cells, and rapid proliferation. |
T2238 |
123-125 |
NN |
denotes |
ES |
T2239 |
126-131 |
NNS |
denotes |
cells |
T2240 |
132-136 |
VBP |
denotes |
have |
T2241 |
137-140 |
CD |
denotes |
two |
T2242 |
151-161 |
NNS |
denotes |
properties |
T2243 |
141-150 |
JJ |
denotes |
important |
T2244 |
161-163 |
: |
denotes |
: |
T2245 |
163-173 |
NN |
denotes |
theability |
T2246 |
174-176 |
TO |
denotes |
to |
T2247 |
177-185 |
VB |
denotes |
maintain |
T2248 |
186-198 |
NN |
denotes |
pluripotency |
T2249 |
198-200 |
, |
denotes |
, |
T2250 |
200-205 |
WDT |
denotes |
which |
T2251 |
206-208 |
VBZ |
denotes |
is |
T2252 |
209-212 |
DT |
denotes |
the |
T2253 |
213-220 |
NN |
denotes |
ability |
T2254 |
221-223 |
TO |
denotes |
to |
T2255 |
224-237 |
VB |
denotes |
differentiate |
T2256 |
238-242 |
IN |
denotes |
into |
T2257 |
243-244 |
DT |
denotes |
a |
T2258 |
250-257 |
NN |
denotes |
variety |
T2259 |
245-249 |
JJ |
denotes |
wide |
T2260 |
258-260 |
IN |
denotes |
of |
T2261 |
261-266 |
NNS |
denotes |
cells |
T2262 |
266-268 |
, |
denotes |
, |
T2263 |
268-271 |
CC |
denotes |
and |
T2264 |
272-277 |
JJ |
denotes |
rapid |
T2265 |
278-291 |
NN |
denotes |
proliferation |
T2266 |
291-292 |
. |
denotes |
. |
T2267 |
292-387 |
sentence |
denotes |
These characteristics make mouse ES cells an essential component of gene targeting technology. |
T2268 |
293-298 |
DT |
denotes |
These |
T2269 |
299-314 |
NNS |
denotes |
characteristics |
T2270 |
315-319 |
VBP |
denotes |
make |
T2271 |
320-325 |
NN |
denotes |
mouse |
T2272 |
329-334 |
NNS |
denotes |
cells |
T2273 |
326-328 |
NN |
denotes |
ES |
T2274 |
348-357 |
NN |
denotes |
component |
T2275 |
335-337 |
DT |
denotes |
an |
T2276 |
338-347 |
JJ |
denotes |
essential |
T2277 |
358-360 |
IN |
denotes |
of |
T2278 |
361-365 |
NN |
denotes |
gene |
T2279 |
366-375 |
NN |
denotes |
targeting |
T2280 |
376-386 |
NN |
denotes |
technology |
T2281 |
386-387 |
. |
denotes |
. |
T2282 |
387-560 |
sentence |
denotes |
These qualitiesalso make human ES cells attractive sources for cell transplantation therapy to treat various diseases, including spinal cord injuries and juvenile diabetes. |
T2283 |
388-393 |
DT |
denotes |
These |
T2284 |
394-403 |
NNS |
denotes |
qualities |
T2285 |
408-412 |
VBP |
denotes |
make |
T2286 |
403-407 |
RB |
denotes |
also |
T2287 |
413-418 |
JJ |
denotes |
human |
T2288 |
422-427 |
NNS |
denotes |
cells |
T2289 |
419-421 |
NN |
denotes |
ES |
T2290 |
439-446 |
NNS |
denotes |
sources |
T2291 |
428-438 |
JJ |
denotes |
attractive |
T2292 |
447-450 |
IN |
denotes |
for |
T2293 |
451-455 |
NN |
denotes |
cell |
T2294 |
456-471 |
NN |
denotes |
transplantation |
T2295 |
472-479 |
NN |
denotes |
therapy |
T2296 |
480-482 |
TO |
denotes |
to |
T2297 |
483-488 |
VB |
denotes |
treat |
T2298 |
489-496 |
JJ |
denotes |
various |
T2299 |
497-505 |
NNS |
denotes |
diseases |
T2300 |
505-507 |
, |
denotes |
, |
T2301 |
507-516 |
VBG |
denotes |
including |
T2302 |
517-523 |
JJ |
denotes |
spinal |
T2303 |
524-528 |
NN |
denotes |
cord |
T2304 |
529-537 |
NNS |
denotes |
injuries |
T2305 |
538-541 |
CC |
denotes |
and |
T2306 |
542-550 |
JJ |
denotes |
juvenile |
T2307 |
551-559 |
NN |
denotes |
diabetes |
T2308 |
559-560 |
. |
denotes |
. |
T2309 |
560-718 |
sentence |
denotes |
The molecular mechanisms underlying the pluripotency and rapid proliferation of ES cells are currently a major focus of the field of stem cell biology [4-6]. |
T2310 |
561-564 |
DT |
denotes |
The |
T2311 |
575-585 |
NNS |
denotes |
mechanisms |
T2312 |
565-574 |
JJ |
denotes |
molecular |
T2313 |
650-653 |
VBP |
denotes |
are |
T2314 |
586-596 |
VBG |
denotes |
underlying |
T2315 |
597-600 |
DT |
denotes |
the |
T2316 |
601-613 |
NN |
denotes |
pluripotency |
T2317 |
614-617 |
CC |
denotes |
and |
T2318 |
618-623 |
JJ |
denotes |
rapid |
T2319 |
624-637 |
NN |
denotes |
proliferation |
T2320 |
638-640 |
IN |
denotes |
of |
T2321 |
641-643 |
NN |
denotes |
ES |
T2322 |
644-649 |
NNS |
denotes |
cells |
T2323 |
654-663 |
RB |
denotes |
currently |
T2324 |
664-665 |
DT |
denotes |
a |
T2325 |
672-677 |
NN |
denotes |
focus |
T2326 |
666-671 |
JJ |
denotes |
major |
T2327 |
678-680 |
IN |
denotes |
of |
T2328 |
681-684 |
DT |
denotes |
the |
T2329 |
685-690 |
NN |
denotes |
field |
T2330 |
691-693 |
IN |
denotes |
of |
T2331 |
694-698 |
NN |
denotes |
stem |
T2332 |
699-703 |
NN |
denotes |
cell |
T2333 |
704-711 |
NN |
denotes |
biology |
T2334 |
712-713 |
-LRB- |
denotes |
[ |
T2335 |
713-714 |
CD |
denotes |
4 |
T2336 |
714-715 |
SYM |
denotes |
- |
T2337 |
715-716 |
CD |
denotes |
6 |
T2338 |
716-717 |
-RRB- |
denotes |
] |
T2339 |
717-718 |
. |
denotes |
. |
T2340 |
718-908 |
sentence |
denotes |
To identify molecules essential in ES cells for these properties, several groups have utilized transcriptome analyses to identify genes specifically expressed in ES cells and early embryos. |
T2341 |
719-721 |
TO |
denotes |
To |
T2342 |
722-730 |
VB |
denotes |
identify |
T2343 |
805-813 |
VBN |
denotes |
utilized |
T2344 |
731-740 |
NNS |
denotes |
molecules |
T2345 |
741-750 |
JJ |
denotes |
essential |
T2346 |
751-753 |
IN |
denotes |
in |
T2347 |
754-756 |
NN |
denotes |
ES |
T2348 |
757-762 |
NNS |
denotes |
cells |
T2349 |
763-766 |
IN |
denotes |
for |
T2350 |
767-772 |
DT |
denotes |
these |
T2351 |
773-783 |
NNS |
denotes |
properties |
T2352 |
783-785 |
, |
denotes |
, |
T2353 |
785-792 |
JJ |
denotes |
several |
T2354 |
793-799 |
NNS |
denotes |
groups |
T2355 |
800-804 |
VBP |
denotes |
have |
T2356 |
814-827 |
NN |
denotes |
transcriptome |
T2357 |
828-836 |
NNS |
denotes |
analyses |
T2358 |
837-839 |
TO |
denotes |
to |
T2359 |
840-848 |
VB |
denotes |
identify |
T2360 |
849-854 |
NNS |
denotes |
genes |
T2361 |
855-867 |
RB |
denotes |
specifically |
T2362 |
868-877 |
VBN |
denotes |
expressed |
T2363 |
878-880 |
IN |
denotes |
in |
T2364 |
881-883 |
NN |
denotes |
ES |
T2365 |
884-889 |
NNS |
denotes |
cells |
T2366 |
890-893 |
CC |
denotes |
and |
T2367 |
894-899 |
JJ |
denotes |
early |
T2368 |
900-907 |
NNS |
denotes |
embryos |
T2369 |
907-908 |
. |
denotes |
. |
T2370 |
908-1101 |
sentence |
denotes |
These analyses, including DNA microarray analyses [7] and expressed sequence tag analyses [8-12], identified several common transcripts, including ESG1 that was also designated dppa5 or ECAT2. |
T2371 |
909-914 |
DT |
denotes |
These |
T2372 |
915-923 |
NNS |
denotes |
analyses |
T2373 |
1007-1017 |
VBD |
denotes |
identified |
T2374 |
923-925 |
, |
denotes |
, |
T2375 |
925-934 |
VBG |
denotes |
including |
T2376 |
935-938 |
NN |
denotes |
DNA |
T2377 |
950-958 |
NNS |
denotes |
analyses |
T2378 |
939-949 |
NN |
denotes |
microarray |
T2379 |
959-960 |
-LRB- |
denotes |
[ |
T2380 |
960-961 |
CD |
denotes |
7 |
T2381 |
961-962 |
-RRB- |
denotes |
] |
T2382 |
963-966 |
CC |
denotes |
and |
T2383 |
967-976 |
VBN |
denotes |
expressed |
T2384 |
977-985 |
NN |
denotes |
sequence |
T2385 |
990-998 |
NNS |
denotes |
analyses |
T2386 |
986-989 |
NN |
denotes |
tag |
T2387 |
999-1000 |
-LRB- |
denotes |
[ |
T2388 |
1000-1001 |
CD |
denotes |
8 |
T2389 |
1001-1002 |
SYM |
denotes |
- |
T2390 |
1002-1004 |
CD |
denotes |
12 |
T2391 |
1004-1005 |
-RRB- |
denotes |
] |
T2392 |
1005-1007 |
, |
denotes |
, |
T2393 |
1018-1025 |
JJ |
denotes |
several |
T2394 |
1033-1044 |
NNS |
denotes |
transcripts |
T2395 |
1026-1032 |
JJ |
denotes |
common |
T2396 |
1044-1046 |
, |
denotes |
, |
T2397 |
1046-1055 |
VBG |
denotes |
including |
T2398 |
1056-1060 |
NN |
denotes |
ESG1 |
T2399 |
1061-1065 |
WDT |
denotes |
that |
T2400 |
1075-1085 |
VBN |
denotes |
designated |
T2401 |
1066-1069 |
VBD |
denotes |
was |
T2402 |
1070-1074 |
RB |
denotes |
also |
T2403 |
1086-1091 |
NN |
denotes |
dppa5 |
T2404 |
1092-1094 |
CC |
denotes |
or |
T2405 |
1095-1100 |
NN |
denotes |
ECAT2 |
T2406 |
1100-1101 |
. |
denotes |
. |
T2407 |
1101-1229 |
sentence |
denotes |
ESG1 was originally identified as a transcript Ph34 that was down-regulated by retinoic acid in embryonic carcinoma cells [13]. |
T2408 |
1102-1106 |
NN |
denotes |
ESG1 |
T2409 |
1122-1132 |
VBN |
denotes |
identified |
T2410 |
1107-1110 |
VBD |
denotes |
was |
T2411 |
1111-1121 |
RB |
denotes |
originally |
T2412 |
1133-1135 |
IN |
denotes |
as |
T2413 |
1136-1137 |
DT |
denotes |
a |
T2414 |
1149-1153 |
NN |
denotes |
Ph34 |
T2415 |
1138-1148 |
NN |
denotes |
transcript |
T2416 |
1154-1158 |
WDT |
denotes |
that |
T2417 |
1168-1177 |
VBN |
denotes |
regulated |
T2418 |
1159-1162 |
VBD |
denotes |
was |
T2419 |
1163-1167 |
RB |
denotes |
down |
T2420 |
1167-1168 |
HYPH |
denotes |
- |
T2421 |
1178-1180 |
IN |
denotes |
by |
T2422 |
1181-1189 |
JJ |
denotes |
retinoic |
T2423 |
1190-1194 |
NN |
denotes |
acid |
T2424 |
1195-1197 |
IN |
denotes |
in |
T2425 |
1198-1207 |
JJ |
denotes |
embryonic |
T2426 |
1208-1217 |
NN |
denotes |
carcinoma |
T2427 |
1218-1223 |
NNS |
denotes |
cells |
T2428 |
1224-1225 |
-LRB- |
denotes |
[ |
T2429 |
1225-1227 |
CD |
denotes |
13 |
T2430 |
1227-1228 |
-RRB- |
denotes |
] |
T2431 |
1228-1229 |
. |
denotes |
. |
T2432 |
1229-1316 |
sentence |
denotes |
The expression of this gene was confined in mice to early embryos and germ cells [14]. |
T2433 |
1230-1233 |
DT |
denotes |
The |
T2434 |
1234-1244 |
NN |
denotes |
expression |
T2435 |
1262-1270 |
VBN |
denotes |
confined |
T2436 |
1245-1247 |
IN |
denotes |
of |
T2437 |
1248-1252 |
DT |
denotes |
this |
T2438 |
1253-1257 |
NN |
denotes |
gene |
T2439 |
1258-1261 |
VBD |
denotes |
was |
T2440 |
1271-1273 |
IN |
denotes |
in |
T2441 |
1274-1278 |
NNS |
denotes |
mice |
T2442 |
1279-1281 |
IN |
denotes |
to |
T2443 |
1282-1287 |
JJ |
denotes |
early |
T2444 |
1288-1295 |
NNS |
denotes |
embryos |
T2445 |
1296-1299 |
CC |
denotes |
and |
T2446 |
1300-1304 |
NN |
denotes |
germ |
T2447 |
1305-1310 |
NNS |
denotes |
cells |
T2448 |
1311-1312 |
-LRB- |
denotes |
[ |
T2449 |
1312-1314 |
CD |
denotes |
14 |
T2450 |
1314-1315 |
-RRB- |
denotes |
] |
T2451 |
1315-1316 |
. |
denotes |
. |
T2452 |
1316-1443 |
sentence |
denotes |
It is also expressed in pluripotent cells, including ES cells, embryonic germ cells, and multipotent germline stem cells [15]. |
T2453 |
1317-1319 |
PRP |
denotes |
It |
T2454 |
1328-1337 |
VBN |
denotes |
expressed |
T2455 |
1320-1322 |
VBZ |
denotes |
is |
T2456 |
1323-1327 |
RB |
denotes |
also |
T2457 |
1338-1340 |
IN |
denotes |
in |
T2458 |
1341-1352 |
JJ |
denotes |
pluripotent |
T2459 |
1353-1358 |
NNS |
denotes |
cells |
T2460 |
1358-1360 |
, |
denotes |
, |
T2461 |
1360-1369 |
VBG |
denotes |
including |
T2462 |
1370-1372 |
NN |
denotes |
ES |
T2463 |
1373-1378 |
NNS |
denotes |
cells |
T2464 |
1378-1380 |
, |
denotes |
, |
T2465 |
1380-1389 |
JJ |
denotes |
embryonic |
T2466 |
1395-1400 |
NNS |
denotes |
cells |
T2467 |
1390-1394 |
NN |
denotes |
germ |
T2468 |
1400-1402 |
, |
denotes |
, |
T2469 |
1402-1405 |
CC |
denotes |
and |
T2470 |
1406-1417 |
JJ |
denotes |
multipotent |
T2471 |
1432-1437 |
NNS |
denotes |
cells |
T2472 |
1418-1426 |
NN |
denotes |
germline |
T2473 |
1427-1431 |
NN |
denotes |
stem |
T2474 |
1438-1439 |
-LRB- |
denotes |
[ |
T2475 |
1439-1441 |
CD |
denotes |
15 |
T2476 |
1441-1442 |
-RRB- |
denotes |
] |
T2477 |
1442-1443 |
. |
denotes |
. |
T2478 |
1443-1560 |
sentence |
denotes |
ESG1 encodes a polypeptide of 118 amino acids that contains a single KH domain, which is an RNA-binding domain [16]. |
T2479 |
1444-1448 |
NN |
denotes |
ESG1 |
T2480 |
1449-1456 |
VBZ |
denotes |
encodes |
T2481 |
1457-1458 |
DT |
denotes |
a |
T2482 |
1459-1470 |
NN |
denotes |
polypeptide |
T2483 |
1471-1473 |
IN |
denotes |
of |
T2484 |
1474-1477 |
CD |
denotes |
118 |
T2485 |
1484-1489 |
NNS |
denotes |
acids |
T2486 |
1478-1483 |
NN |
denotes |
amino |
T2487 |
1490-1494 |
WDT |
denotes |
that |
T2488 |
1495-1503 |
VBZ |
denotes |
contains |
T2489 |
1504-1505 |
DT |
denotes |
a |
T2490 |
1516-1522 |
NN |
denotes |
domain |
T2491 |
1506-1512 |
JJ |
denotes |
single |
T2492 |
1513-1515 |
NN |
denotes |
KH |
T2493 |
1522-1524 |
, |
denotes |
, |
T2494 |
1524-1529 |
WDT |
denotes |
which |
T2495 |
1530-1532 |
VBZ |
denotes |
is |
T2496 |
1533-1535 |
DT |
denotes |
an |
T2497 |
1548-1554 |
NN |
denotes |
domain |
T2498 |
1536-1539 |
NN |
denotes |
RNA |
T2499 |
1540-1547 |
VBG |
denotes |
binding |
T2500 |
1539-1540 |
HYPH |
denotes |
- |
T2501 |
1555-1556 |
-LRB- |
denotes |
[ |
T2502 |
1556-1558 |
CD |
denotes |
16 |
T2503 |
1558-1559 |
-RRB- |
denotes |
] |
T2504 |
1559-1560 |
. |
denotes |
. |
T2505 |
1560-1677 |
sentence |
denotes |
It remains unclear, however, if ESG1 functions as an RNA-binding protein or the roles it plays in ES cells and mice. |
T2506 |
1561-1563 |
PRP |
denotes |
It |
T2507 |
1564-1571 |
VBZ |
denotes |
remains |
T2508 |
1572-1579 |
JJ |
denotes |
unclear |
T2509 |
1579-1581 |
, |
denotes |
, |
T2510 |
1581-1588 |
RB |
denotes |
however |
T2511 |
1588-1590 |
, |
denotes |
, |
T2512 |
1590-1592 |
IN |
denotes |
if |
T2513 |
1598-1607 |
VBZ |
denotes |
functions |
T2514 |
1593-1597 |
NN |
denotes |
ESG1 |
T2515 |
1608-1610 |
IN |
denotes |
as |
T2516 |
1611-1613 |
DT |
denotes |
an |
T2517 |
1626-1633 |
NN |
denotes |
protein |
T2518 |
1614-1617 |
NN |
denotes |
RNA |
T2519 |
1618-1625 |
VBG |
denotes |
binding |
T2520 |
1617-1618 |
HYPH |
denotes |
- |
T2521 |
1634-1636 |
CC |
denotes |
or |
T2522 |
1637-1640 |
DT |
denotes |
the |
T2523 |
1641-1646 |
NNS |
denotes |
roles |
T2524 |
1647-1649 |
PRP |
denotes |
it |
T2525 |
1650-1655 |
VBZ |
denotes |
plays |
T2526 |
1656-1658 |
IN |
denotes |
in |
T2527 |
1659-1661 |
NN |
denotes |
ES |
T2528 |
1662-1667 |
NNS |
denotes |
cells |
T2529 |
1668-1671 |
CC |
denotes |
and |
T2530 |
1672-1676 |
NNS |
denotes |
mice |
T2531 |
1676-1677 |
. |
denotes |
. |
T2532 |
1677-1800 |
sentence |
denotes |
Previous genomic library screening by identified genomic clones containing the mouse ESG1 gene and seven pseudogenes [17]. |
T2533 |
1678-1686 |
JJ |
denotes |
Previous |
T2534 |
1703-1712 |
NN |
denotes |
screening |
T2535 |
1687-1694 |
JJ |
denotes |
genomic |
T2536 |
1695-1702 |
NN |
denotes |
library |
T2537 |
1713-1715 |
IN |
denotes |
by |
T2538 |
1716-1726 |
VBN |
denotes |
identified |
T2539 |
1735-1741 |
NNS |
denotes |
clones |
T2540 |
1727-1734 |
JJ |
denotes |
genomic |
T2541 |
1742-1752 |
VBG |
denotes |
containing |
T2542 |
1753-1756 |
DT |
denotes |
the |
T2543 |
1768-1772 |
NN |
denotes |
gene |
T2544 |
1757-1762 |
NN |
denotes |
mouse |
T2545 |
1763-1767 |
NN |
denotes |
ESG1 |
T2546 |
1773-1776 |
CC |
denotes |
and |
T2547 |
1777-1782 |
CD |
denotes |
seven |
T2548 |
1783-1794 |
NNS |
denotes |
pseudogenes |
T2549 |
1795-1796 |
-LRB- |
denotes |
[ |
T2550 |
1796-1798 |
CD |
denotes |
17 |
T2551 |
1798-1799 |
-RRB- |
denotes |
] |
T2552 |
1799-1800 |
. |
denotes |
. |
T2553 |
1800-1932 |
sentence |
denotes |
Two of these pseudogenes exhibit a similar exon-intron structure as the ESG1 gene, indicating their generation by gene duplication. |
T2554 |
1801-1804 |
CD |
denotes |
Two |
T2555 |
1826-1833 |
VBP |
denotes |
exhibit |
T2556 |
1805-1807 |
IN |
denotes |
of |
T2557 |
1808-1813 |
DT |
denotes |
these |
T2558 |
1814-1825 |
NNS |
denotes |
pseudogenes |
T2559 |
1834-1835 |
DT |
denotes |
a |
T2560 |
1856-1865 |
NN |
denotes |
structure |
T2561 |
1836-1843 |
JJ |
denotes |
similar |
T2562 |
1844-1848 |
NN |
denotes |
exon |
T2563 |
1849-1855 |
NN |
denotes |
intron |
T2564 |
1848-1849 |
HYPH |
denotes |
- |
T2565 |
1866-1868 |
IN |
denotes |
as |
T2566 |
1869-1872 |
DT |
denotes |
the |
T2567 |
1878-1882 |
NN |
denotes |
gene |
T2568 |
1873-1877 |
NN |
denotes |
ESG1 |
T2569 |
1882-1884 |
, |
denotes |
, |
T2570 |
1884-1894 |
VBG |
denotes |
indicating |
T2571 |
1895-1900 |
PRP$ |
denotes |
their |
T2572 |
1901-1911 |
NN |
denotes |
generation |
T2573 |
1912-1914 |
IN |
denotes |
by |
T2574 |
1915-1919 |
NN |
denotes |
gene |
T2575 |
1920-1931 |
NN |
denotes |
duplication |
T2576 |
1931-1932 |
. |
denotes |
. |
T2577 |
1932-2072 |
sentence |
denotes |
The five remaining pseudogenes did not contain any introns, indicating that these were generated by retrotransposition of ESG1 transcripts. |
T2578 |
1933-1936 |
DT |
denotes |
The |
T2579 |
1952-1963 |
NNS |
denotes |
pseudogenes |
T2580 |
1937-1941 |
CD |
denotes |
five |
T2581 |
1942-1951 |
VBG |
denotes |
remaining |
T2582 |
1972-1979 |
VB |
denotes |
contain |
T2583 |
1964-1967 |
VBD |
denotes |
did |
T2584 |
1968-1971 |
RB |
denotes |
not |
T2585 |
1980-1983 |
DT |
denotes |
any |
T2586 |
1984-1991 |
NNS |
denotes |
introns |
T2587 |
1991-1993 |
, |
denotes |
, |
T2588 |
1993-2003 |
VBG |
denotes |
indicating |
T2589 |
2004-2008 |
IN |
denotes |
that |
T2590 |
2020-2029 |
VBN |
denotes |
generated |
T2591 |
2009-2014 |
DT |
denotes |
these |
T2592 |
2015-2019 |
VBD |
denotes |
were |
T2593 |
2030-2032 |
IN |
denotes |
by |
T2594 |
2033-2051 |
NN |
denotes |
retrotransposition |
T2595 |
2052-2054 |
IN |
denotes |
of |
T2596 |
2055-2059 |
NN |
denotes |
ESG1 |
T2597 |
2060-2071 |
NNS |
denotes |
transcripts |
T2598 |
2071-2072 |
. |
denotes |
. |
T2599 |
2072-2175 |
sentence |
denotes |
The chromosomal localizations of the mouse ESG1 gene and pseudogenes, however, have not been reported. |
T2600 |
2073-2076 |
DT |
denotes |
The |
T2601 |
2089-2102 |
NNS |
denotes |
localizations |
T2602 |
2077-2088 |
JJ |
denotes |
chromosomal |
T2603 |
2166-2174 |
VBN |
denotes |
reported |
T2604 |
2103-2105 |
IN |
denotes |
of |
T2605 |
2106-2109 |
DT |
denotes |
the |
T2606 |
2121-2125 |
NN |
denotes |
gene |
T2607 |
2110-2115 |
NN |
denotes |
mouse |
T2608 |
2116-2120 |
NN |
denotes |
ESG1 |
T2609 |
2126-2129 |
CC |
denotes |
and |
T2610 |
2130-2141 |
NNS |
denotes |
pseudogenes |
T2611 |
2141-2143 |
, |
denotes |
, |
T2612 |
2143-2150 |
RB |
denotes |
however |
T2613 |
2150-2152 |
, |
denotes |
, |
T2614 |
2152-2156 |
VBP |
denotes |
have |
T2615 |
2157-2160 |
RB |
denotes |
not |
T2616 |
2161-2165 |
VBN |
denotes |
been |
T2617 |
2174-2175 |
. |
denotes |
. |
T2618 |
2175-2283 |
sentence |
denotes |
In this study, we determined the structure of the mouse gene encoding this protein and related pseudogenes. |
T2619 |
2176-2178 |
IN |
denotes |
In |
T2620 |
2194-2204 |
VBD |
denotes |
determined |
T2621 |
2179-2183 |
DT |
denotes |
this |
T2622 |
2184-2189 |
NN |
denotes |
study |
T2623 |
2189-2191 |
, |
denotes |
, |
T2624 |
2191-2193 |
PRP |
denotes |
we |
T2625 |
2205-2208 |
DT |
denotes |
the |
T2626 |
2209-2218 |
NN |
denotes |
structure |
T2627 |
2219-2221 |
IN |
denotes |
of |
T2628 |
2222-2225 |
DT |
denotes |
the |
T2629 |
2232-2236 |
NN |
denotes |
gene |
T2630 |
2226-2231 |
NN |
denotes |
mouse |
T2631 |
2237-2245 |
VBG |
denotes |
encoding |
T2632 |
2246-2250 |
DT |
denotes |
this |
T2633 |
2251-2258 |
NN |
denotes |
protein |
T2634 |
2259-2262 |
CC |
denotes |
and |
T2635 |
2263-2270 |
JJ |
denotes |
related |
T2636 |
2271-2282 |
NNS |
denotes |
pseudogenes |
T2637 |
2282-2283 |
. |
denotes |
. |
T2638 |
2283-2365 |
sentence |
denotes |
We also performed gene targeting to determine the physiological function of ESG1. |
T2639 |
2284-2286 |
PRP |
denotes |
We |
T2640 |
2292-2301 |
VBD |
denotes |
performed |
T2641 |
2287-2291 |
RB |
denotes |
also |
T2642 |
2302-2306 |
NN |
denotes |
gene |
T2643 |
2307-2316 |
NN |
denotes |
targeting |
T2644 |
2317-2319 |
TO |
denotes |
to |
T2645 |
2320-2329 |
VB |
denotes |
determine |
T2646 |
2330-2333 |
DT |
denotes |
the |
T2647 |
2348-2356 |
NN |
denotes |
function |
T2648 |
2334-2347 |
JJ |
denotes |
physiological |
T2649 |
2357-2359 |
IN |
denotes |
of |
T2650 |
2360-2364 |
NN |
denotes |
ESG1 |
T2651 |
2364-2365 |
. |
denotes |
. |
R325 |
T2208 |
T2209 |
amod |
Embryonic,stem |
R326 |
T2209 |
T2210 |
nmod |
stem,cells |
R327 |
T2210 |
T2214 |
nsubjpass |
cells,derived |
R328 |
T2211 |
T2209 |
punct |
(,stem |
R329 |
T2212 |
T2209 |
appos |
ES,stem |
R330 |
T2213 |
T2210 |
punct |
),cells |
R331 |
T2215 |
T2214 |
auxpass |
were,derived |
R332 |
T2216 |
T2214 |
advmod |
first,derived |
R333 |
T2217 |
T2214 |
prep |
from,derived |
R334 |
T2218 |
T2219 |
det |
the,blastocysts |
R335 |
T2219 |
T2217 |
pobj |
blastocysts,from |
R336 |
T2220 |
T2219 |
prep |
of,blastocysts |
R337 |
T2221 |
T2220 |
pobj |
mice,of |
R338 |
T2222 |
T2214 |
prep |
in,derived |
R339 |
T2223 |
T2222 |
pobj |
1981,in |
R340 |
T2224 |
T2225 |
punct |
[,2 |
R341 |
T2225 |
T2223 |
parataxis |
2,1981 |
R342 |
T2226 |
T2225 |
nummod |
1,2 |
R343 |
T2227 |
T2225 |
punct |
",",2 |
R344 |
T2228 |
T2225 |
punct |
],2 |
R345 |
T2229 |
T2214 |
cc |
and,derived |
R346 |
T2230 |
T2214 |
conj |
humans,derived |
R347 |
T2231 |
T2230 |
prep |
in,humans |
R348 |
T2232 |
T2231 |
pobj |
1998,in |
R349 |
T2233 |
T2234 |
punct |
[,3 |
R350 |
T2234 |
T2232 |
parataxis |
3,1998 |
R351 |
T2235 |
T2234 |
punct |
],3 |
R352 |
T2236 |
T2214 |
punct |
.,derived |
R353 |
T2238 |
T2239 |
compound |
ES,cells |
R354 |
T2239 |
T2240 |
nsubj |
cells,have |
R355 |
T2241 |
T2242 |
nummod |
two,properties |
R356 |
T2242 |
T2240 |
dobj |
properties,have |
R357 |
T2243 |
T2242 |
amod |
important,properties |
R358 |
T2244 |
T2242 |
punct |
: ,properties |
R359 |
T2245 |
T2242 |
appos |
theability,properties |
R360 |
T2246 |
T2247 |
aux |
to,maintain |
R361 |
T2247 |
T2245 |
acl |
maintain,theability |
R362 |
T2248 |
T2247 |
dobj |
pluripotency,maintain |
R363 |
T2249 |
T2248 |
punct |
", ",pluripotency |
R364 |
T2250 |
T2251 |
dep |
which,is |
R365 |
T2251 |
T2248 |
relcl |
is,pluripotency |
R366 |
T2252 |
T2253 |
det |
the,ability |
R367 |
T2253 |
T2251 |
attr |
ability,is |
R368 |
T2254 |
T2255 |
aux |
to,differentiate |
R369 |
T2255 |
T2253 |
acl |
differentiate,ability |
R370 |
T2256 |
T2255 |
prep |
into,differentiate |
R371 |
T2257 |
T2258 |
det |
a,variety |
R372 |
T2258 |
T2256 |
pobj |
variety,into |
R373 |
T2259 |
T2258 |
amod |
wide,variety |
R374 |
T2260 |
T2258 |
prep |
of,variety |
R375 |
T2261 |
T2260 |
pobj |
cells,of |
R376 |
T2262 |
T2245 |
punct |
", ",theability |
R377 |
T2263 |
T2245 |
cc |
and,theability |
R378 |
T2264 |
T2265 |
amod |
rapid,proliferation |
R379 |
T2265 |
T2245 |
conj |
proliferation,theability |
R380 |
T2266 |
T2240 |
punct |
.,have |
R381 |
T2268 |
T2269 |
det |
These,characteristics |
R382 |
T2269 |
T2270 |
nsubj |
characteristics,make |
R383 |
T2271 |
T2272 |
compound |
mouse,cells |
R384 |
T2272 |
T2274 |
nsubj |
cells,component |
R385 |
T2273 |
T2272 |
compound |
ES,cells |
R386 |
T2274 |
T2270 |
ccomp |
component,make |
R387 |
T2275 |
T2274 |
det |
an,component |
R388 |
T2276 |
T2274 |
amod |
essential,component |
R389 |
T2277 |
T2274 |
prep |
of,component |
R390 |
T2278 |
T2279 |
compound |
gene,targeting |
R391 |
T2279 |
T2280 |
compound |
targeting,technology |
R392 |
T2280 |
T2277 |
pobj |
technology,of |
R393 |
T2281 |
T2270 |
punct |
.,make |
R394 |
T2283 |
T2284 |
det |
These,qualities |
R395 |
T2284 |
T2285 |
nsubj |
qualities,make |
R396 |
T2286 |
T2285 |
advmod |
also,make |
R397 |
T2287 |
T2288 |
amod |
human,cells |
R398 |
T2288 |
T2290 |
nsubj |
cells,sources |
R399 |
T2289 |
T2288 |
compound |
ES,cells |
R400 |
T2290 |
T2285 |
ccomp |
sources,make |
R401 |
T2291 |
T2290 |
amod |
attractive,sources |
R402 |
T2292 |
T2290 |
prep |
for,sources |
R403 |
T2293 |
T2294 |
compound |
cell,transplantation |
R404 |
T2294 |
T2295 |
compound |
transplantation,therapy |
R405 |
T2295 |
T2292 |
pobj |
therapy,for |
R406 |
T2296 |
T2297 |
aux |
to,treat |
R407 |
T2297 |
T2295 |
advcl |
treat,therapy |
R408 |
T2298 |
T2299 |
amod |
various,diseases |
R409 |
T2299 |
T2297 |
dobj |
diseases,treat |
R410 |
T2300 |
T2299 |
punct |
", ",diseases |
R411 |
T2301 |
T2299 |
prep |
including,diseases |
R412 |
T2302 |
T2303 |
amod |
spinal,cord |
R413 |
T2303 |
T2304 |
compound |
cord,injuries |
R414 |
T2304 |
T2301 |
pobj |
injuries,including |
R415 |
T2305 |
T2304 |
cc |
and,injuries |
R416 |
T2306 |
T2307 |
amod |
juvenile,diabetes |
R417 |
T2307 |
T2304 |
conj |
diabetes,injuries |
R418 |
T2308 |
T2285 |
punct |
.,make |
R419 |
T2310 |
T2311 |
det |
The,mechanisms |
R420 |
T2311 |
T2313 |
nsubj |
mechanisms,are |
R421 |
T2312 |
T2311 |
amod |
molecular,mechanisms |
R422 |
T2314 |
T2311 |
acl |
underlying,mechanisms |
R423 |
T2315 |
T2316 |
det |
the,pluripotency |
R424 |
T2316 |
T2314 |
dobj |
pluripotency,underlying |
R425 |
T2317 |
T2316 |
cc |
and,pluripotency |
R426 |
T2318 |
T2319 |
amod |
rapid,proliferation |
R427 |
T2319 |
T2316 |
conj |
proliferation,pluripotency |
R428 |
T2320 |
T2316 |
prep |
of,pluripotency |
R429 |
T2321 |
T2322 |
compound |
ES,cells |
R430 |
T2322 |
T2320 |
pobj |
cells,of |
R431 |
T2323 |
T2313 |
advmod |
currently,are |
R432 |
T2324 |
T2325 |
det |
a,focus |
R433 |
T2325 |
T2313 |
attr |
focus,are |
R434 |
T2326 |
T2325 |
amod |
major,focus |
R435 |
T2327 |
T2325 |
prep |
of,focus |
R436 |
T2328 |
T2329 |
det |
the,field |
R437 |
T2329 |
T2327 |
pobj |
field,of |
R438 |
T2330 |
T2329 |
prep |
of,field |
R439 |
T2331 |
T2332 |
compound |
stem,cell |
R440 |
T2332 |
T2333 |
compound |
cell,biology |
R441 |
T2333 |
T2330 |
pobj |
biology,of |
R442 |
T2334 |
T2335 |
punct |
[,4 |
R443 |
T2335 |
T2313 |
parataxis |
4,are |
R444 |
T2336 |
T2337 |
punct |
-,6 |
R445 |
T2337 |
T2335 |
prep |
6,4 |
R446 |
T2338 |
T2335 |
punct |
],4 |
R447 |
T2339 |
T2313 |
punct |
.,are |
R448 |
T2341 |
T2342 |
aux |
To,identify |
R449 |
T2342 |
T2343 |
advcl |
identify,utilized |
R450 |
T2344 |
T2342 |
dobj |
molecules,identify |
R451 |
T2345 |
T2344 |
relcl |
essential,molecules |
R452 |
T2346 |
T2345 |
prep |
in,essential |
R453 |
T2347 |
T2348 |
compound |
ES,cells |
R454 |
T2348 |
T2346 |
pobj |
cells,in |
R455 |
T2349 |
T2345 |
prep |
for,essential |
R456 |
T2350 |
T2351 |
det |
these,properties |
R457 |
T2351 |
T2349 |
pobj |
properties,for |
R458 |
T2352 |
T2343 |
punct |
", ",utilized |
R459 |
T2353 |
T2354 |
amod |
several,groups |
R460 |
T2354 |
T2343 |
nsubj |
groups,utilized |
R461 |
T2355 |
T2343 |
aux |
have,utilized |
R462 |
T2356 |
T2357 |
compound |
transcriptome,analyses |
R463 |
T2357 |
T2343 |
dobj |
analyses,utilized |
R464 |
T2358 |
T2359 |
aux |
to,identify |
R465 |
T2359 |
T2343 |
advcl |
identify,utilized |
R466 |
T2360 |
T2359 |
dobj |
genes,identify |
R467 |
T2361 |
T2362 |
advmod |
specifically,expressed |
R468 |
T2362 |
T2360 |
acl |
expressed,genes |
R469 |
T2363 |
T2362 |
prep |
in,expressed |
R470 |
T2364 |
T2365 |
compound |
ES,cells |
R471 |
T2365 |
T2363 |
pobj |
cells,in |
R472 |
T2366 |
T2365 |
cc |
and,cells |
R473 |
T2367 |
T2368 |
amod |
early,embryos |
R474 |
T2368 |
T2365 |
conj |
embryos,cells |
R475 |
T2369 |
T2343 |
punct |
.,utilized |
R476 |
T2371 |
T2372 |
det |
These,analyses |
R477 |
T2372 |
T2373 |
nsubj |
analyses,identified |
R478 |
T2374 |
T2372 |
punct |
", ",analyses |
R479 |
T2375 |
T2372 |
prep |
including,analyses |
R480 |
T2376 |
T2377 |
compound |
DNA,analyses |
R481 |
T2377 |
T2375 |
pobj |
analyses,including |
R482 |
T2378 |
T2377 |
compound |
microarray,analyses |
R483 |
T2379 |
T2380 |
punct |
[,7 |
R484 |
T2380 |
T2377 |
parataxis |
7,analyses |
R485 |
T2381 |
T2380 |
punct |
],7 |
R486 |
T2382 |
T2377 |
cc |
and,analyses |
R487 |
T2383 |
T2384 |
amod |
expressed,sequence |
R488 |
T2384 |
T2385 |
compound |
sequence,analyses |
R489 |
T2385 |
T2377 |
conj |
analyses,analyses |
R490 |
T2386 |
T2385 |
compound |
tag,analyses |
R491 |
T2387 |
T2388 |
punct |
[,8 |
R492 |
T2388 |
T2385 |
parataxis |
8,analyses |
R493 |
T2389 |
T2390 |
punct |
-,12 |
R494 |
T2390 |
T2388 |
prep |
12,8 |
R495 |
T2391 |
T2388 |
punct |
],8 |
R496 |
T2392 |
T2373 |
punct |
", ",identified |
R497 |
T2393 |
T2394 |
amod |
several,transcripts |
R498 |
T2394 |
T2373 |
dobj |
transcripts,identified |
R499 |
T2395 |
T2394 |
amod |
common,transcripts |
R500 |
T2396 |
T2394 |
punct |
", ",transcripts |
R501 |
T2397 |
T2394 |
prep |
including,transcripts |
R502 |
T2398 |
T2397 |
pobj |
ESG1,including |
R503 |
T2399 |
T2400 |
dep |
that,designated |
R504 |
T2400 |
T2394 |
relcl |
designated,transcripts |
R505 |
T2401 |
T2400 |
auxpass |
was,designated |
R506 |
T2402 |
T2400 |
advmod |
also,designated |
R507 |
T2403 |
T2400 |
oprd |
dppa5,designated |
R508 |
T2404 |
T2403 |
cc |
or,dppa5 |
R509 |
T2405 |
T2403 |
conj |
ECAT2,dppa5 |
R510 |
T2406 |
T2373 |
punct |
.,identified |
R511 |
T2408 |
T2409 |
nsubjpass |
ESG1,identified |
R512 |
T2410 |
T2409 |
auxpass |
was,identified |
R513 |
T2411 |
T2409 |
advmod |
originally,identified |
R514 |
T2412 |
T2409 |
prep |
as,identified |
R515 |
T2413 |
T2414 |
det |
a,Ph34 |
R516 |
T2414 |
T2412 |
pobj |
Ph34,as |
R517 |
T2415 |
T2414 |
compound |
transcript,Ph34 |
R518 |
T2416 |
T2417 |
dep |
that,regulated |
R519 |
T2417 |
T2414 |
relcl |
regulated,Ph34 |
R520 |
T2418 |
T2417 |
auxpass |
was,regulated |
R521 |
T2419 |
T2417 |
advmod |
down,regulated |
R522 |
T2420 |
T2417 |
punct |
-,regulated |
R523 |
T2421 |
T2417 |
agent |
by,regulated |
R524 |
T2422 |
T2423 |
amod |
retinoic,acid |
R525 |
T2423 |
T2421 |
pobj |
acid,by |
R526 |
T2424 |
T2417 |
prep |
in,regulated |
R527 |
T2425 |
T2426 |
amod |
embryonic,carcinoma |
R528 |
T2426 |
T2427 |
compound |
carcinoma,cells |
R529 |
T2427 |
T2424 |
pobj |
cells,in |
R530 |
T2428 |
T2429 |
punct |
[,13 |
R531 |
T2429 |
T2417 |
parataxis |
13,regulated |
R532 |
T2430 |
T2429 |
punct |
],13 |
R533 |
T2431 |
T2409 |
punct |
.,identified |
R534 |
T2433 |
T2434 |
det |
The,expression |
R535 |
T2434 |
T2435 |
nsubjpass |
expression,confined |
R536 |
T2436 |
T2434 |
prep |
of,expression |
R537 |
T2437 |
T2438 |
det |
this,gene |
R538 |
T2438 |
T2436 |
pobj |
gene,of |
R539 |
T2439 |
T2435 |
auxpass |
was,confined |
R540 |
T2440 |
T2435 |
prep |
in,confined |
R541 |
T2441 |
T2440 |
pobj |
mice,in |
R542 |
T2442 |
T2435 |
prep |
to,confined |
R543 |
T2443 |
T2444 |
amod |
early,embryos |
R544 |
T2444 |
T2442 |
pobj |
embryos,to |
R545 |
T2445 |
T2444 |
cc |
and,embryos |
R546 |
T2446 |
T2447 |
compound |
germ,cells |
R547 |
T2447 |
T2444 |
conj |
cells,embryos |
R548 |
T2448 |
T2449 |
punct |
[,14 |
R549 |
T2449 |
T2435 |
parataxis |
14,confined |
R550 |
T2450 |
T2449 |
punct |
],14 |
R551 |
T2451 |
T2435 |
punct |
.,confined |
R552 |
T2453 |
T2454 |
nsubjpass |
It,expressed |
R553 |
T2455 |
T2454 |
auxpass |
is,expressed |
R554 |
T2456 |
T2454 |
advmod |
also,expressed |
R555 |
T2457 |
T2454 |
prep |
in,expressed |
R556 |
T2458 |
T2459 |
amod |
pluripotent,cells |
R557 |
T2459 |
T2457 |
pobj |
cells,in |
R558 |
T2460 |
T2459 |
punct |
", ",cells |
R559 |
T2461 |
T2459 |
prep |
including,cells |
R560 |
T2462 |
T2463 |
compound |
ES,cells |
R561 |
T2463 |
T2461 |
pobj |
cells,including |
R562 |
T2464 |
T2463 |
punct |
", ",cells |
R563 |
T2465 |
T2466 |
amod |
embryonic,cells |
R564 |
T2466 |
T2463 |
conj |
cells,cells |
R565 |
T2467 |
T2466 |
compound |
germ,cells |
R566 |
T2468 |
T2466 |
punct |
", ",cells |
R567 |
T2469 |
T2466 |
cc |
and,cells |
R568 |
T2470 |
T2471 |
amod |
multipotent,cells |
R569 |
T2471 |
T2466 |
conj |
cells,cells |
R570 |
T2472 |
T2471 |
compound |
germline,cells |
R571 |
T2473 |
T2471 |
compound |
stem,cells |
R572 |
T2474 |
T2475 |
punct |
[,15 |
R573 |
T2475 |
T2454 |
parataxis |
15,expressed |
R574 |
T2476 |
T2475 |
punct |
],15 |
R575 |
T2477 |
T2454 |
punct |
.,expressed |
R576 |
T2479 |
T2480 |
nsubj |
ESG1,encodes |
R577 |
T2481 |
T2482 |
det |
a,polypeptide |
R578 |
T2482 |
T2480 |
dobj |
polypeptide,encodes |
R579 |
T2483 |
T2482 |
prep |
of,polypeptide |
R580 |
T2484 |
T2485 |
nummod |
118,acids |
R581 |
T2485 |
T2483 |
pobj |
acids,of |
R582 |
T2486 |
T2485 |
compound |
amino,acids |
R583 |
T2487 |
T2488 |
dep |
that,contains |
R584 |
T2488 |
T2482 |
relcl |
contains,polypeptide |
R585 |
T2489 |
T2490 |
det |
a,domain |
R586 |
T2490 |
T2488 |
dobj |
domain,contains |
R587 |
T2491 |
T2490 |
amod |
single,domain |
R588 |
T2492 |
T2490 |
compound |
KH,domain |
R589 |
T2493 |
T2490 |
punct |
", ",domain |
R590 |
T2494 |
T2495 |
dep |
which,is |
R591 |
T2495 |
T2490 |
relcl |
is,domain |
R592 |
T2496 |
T2497 |
det |
an,domain |
R593 |
T2497 |
T2495 |
attr |
domain,is |
R594 |
T2498 |
T2499 |
npadvmod |
RNA,binding |
R595 |
T2499 |
T2497 |
amod |
binding,domain |
R596 |
T2500 |
T2499 |
punct |
-,binding |
R597 |
T2501 |
T2502 |
punct |
[,16 |
R598 |
T2502 |
T2495 |
parataxis |
16,is |
R599 |
T2503 |
T2502 |
punct |
],16 |
R600 |
T2504 |
T2480 |
punct |
.,encodes |
R601 |
T2506 |
T2507 |
nsubj |
It,remains |
R602 |
T2508 |
T2507 |
acomp |
unclear,remains |
R603 |
T2509 |
T2507 |
punct |
", ",remains |
R604 |
T2510 |
T2507 |
advmod |
however,remains |
R605 |
T2511 |
T2507 |
punct |
", ",remains |
R606 |
T2512 |
T2513 |
mark |
if,functions |
R607 |
T2513 |
T2507 |
ccomp |
functions,remains |
R608 |
T2514 |
T2513 |
nsubj |
ESG1,functions |
R609 |
T2515 |
T2513 |
prep |
as,functions |
R610 |
T2516 |
T2517 |
det |
an,protein |
R611 |
T2517 |
T2515 |
pobj |
protein,as |
R612 |
T2518 |
T2519 |
npadvmod |
RNA,binding |
R613 |
T2519 |
T2517 |
amod |
binding,protein |
R614 |
T2520 |
T2519 |
punct |
-,binding |
R615 |
T2521 |
T2513 |
cc |
or,functions |
R616 |
T2522 |
T2523 |
det |
the,roles |
R617 |
T2523 |
T2513 |
conj |
roles,functions |
R618 |
T2524 |
T2525 |
nsubj |
it,plays |
R619 |
T2525 |
T2523 |
advcl |
plays,roles |
R620 |
T2526 |
T2525 |
prep |
in,plays |
R621 |
T2527 |
T2528 |
compound |
ES,cells |
R622 |
T2528 |
T2526 |
pobj |
cells,in |
R623 |
T2529 |
T2528 |
cc |
and,cells |
R624 |
T2530 |
T2528 |
conj |
mice,cells |
R625 |
T2531 |
T2507 |
punct |
.,remains |
R626 |
T2533 |
T2534 |
amod |
Previous,screening |
R627 |
T2535 |
T2536 |
amod |
genomic,library |
R628 |
T2536 |
T2534 |
compound |
library,screening |
R629 |
T2537 |
T2534 |
prep |
by,screening |
R630 |
T2538 |
T2539 |
amod |
identified,clones |
R631 |
T2539 |
T2537 |
pobj |
clones,by |
R632 |
T2540 |
T2539 |
amod |
genomic,clones |
R633 |
T2541 |
T2539 |
acl |
containing,clones |
R634 |
T2542 |
T2543 |
det |
the,gene |
R635 |
T2543 |
T2541 |
dobj |
gene,containing |
R636 |
T2544 |
T2543 |
compound |
mouse,gene |
R637 |
T2545 |
T2543 |
compound |
ESG1,gene |
R638 |
T2546 |
T2543 |
cc |
and,gene |
R639 |
T2547 |
T2548 |
nummod |
seven,pseudogenes |
R640 |
T2548 |
T2543 |
conj |
pseudogenes,gene |
R641 |
T2549 |
T2550 |
punct |
[,17 |
R642 |
T2550 |
T2541 |
parataxis |
17,containing |
R643 |
T2551 |
T2550 |
punct |
],17 |
R644 |
T2552 |
T2534 |
punct |
.,screening |
R645 |
T2554 |
T2555 |
nsubj |
Two,exhibit |
R646 |
T2556 |
T2554 |
prep |
of,Two |
R647 |
T2557 |
T2558 |
det |
these,pseudogenes |
R648 |
T2558 |
T2556 |
pobj |
pseudogenes,of |
R649 |
T2559 |
T2560 |
det |
a,structure |
R650 |
T2560 |
T2555 |
dobj |
structure,exhibit |
R651 |
T2561 |
T2560 |
amod |
similar,structure |
R652 |
T2562 |
T2563 |
compound |
exon,intron |
R653 |
T2563 |
T2560 |
compound |
intron,structure |
R654 |
T2564 |
T2563 |
punct |
-,intron |
R655 |
T2565 |
T2560 |
prep |
as,structure |
R656 |
T2566 |
T2567 |
det |
the,gene |
R657 |
T2567 |
T2565 |
pobj |
gene,as |
R658 |
T2568 |
T2567 |
compound |
ESG1,gene |
R659 |
T2569 |
T2555 |
punct |
", ",exhibit |
R660 |
T2570 |
T2555 |
advcl |
indicating,exhibit |
R661 |
T2571 |
T2572 |
poss |
their,generation |
R662 |
T2572 |
T2570 |
dobj |
generation,indicating |
R663 |
T2573 |
T2570 |
prep |
by,indicating |
R664 |
T2574 |
T2575 |
compound |
gene,duplication |
R665 |
T2575 |
T2573 |
pobj |
duplication,by |
R666 |
T2576 |
T2555 |
punct |
.,exhibit |
R667 |
T2578 |
T2579 |
det |
The,pseudogenes |
R668 |
T2579 |
T2582 |
nsubj |
pseudogenes,contain |
R669 |
T2580 |
T2579 |
nummod |
five,pseudogenes |
R670 |
T2581 |
T2579 |
amod |
remaining,pseudogenes |
R671 |
T2583 |
T2582 |
aux |
did,contain |
R672 |
T2584 |
T2582 |
neg |
not,contain |
R673 |
T2585 |
T2586 |
det |
any,introns |
R674 |
T2586 |
T2582 |
dobj |
introns,contain |
R675 |
T2587 |
T2582 |
punct |
", ",contain |
R676 |
T2588 |
T2582 |
advcl |
indicating,contain |
R677 |
T2589 |
T2590 |
mark |
that,generated |
R678 |
T2590 |
T2588 |
ccomp |
generated,indicating |
R679 |
T2591 |
T2590 |
nsubjpass |
these,generated |
R680 |
T2592 |
T2590 |
auxpass |
were,generated |
R681 |
T2593 |
T2590 |
agent |
by,generated |
R682 |
T2594 |
T2593 |
pobj |
retrotransposition,by |
R683 |
T2595 |
T2594 |
prep |
of,retrotransposition |
R684 |
T2596 |
T2597 |
compound |
ESG1,transcripts |
R685 |
T2597 |
T2595 |
pobj |
transcripts,of |
R686 |
T2598 |
T2582 |
punct |
.,contain |
R687 |
T2600 |
T2601 |
det |
The,localizations |
R688 |
T2601 |
T2603 |
nsubjpass |
localizations,reported |
R689 |
T2602 |
T2601 |
amod |
chromosomal,localizations |
R690 |
T2604 |
T2601 |
prep |
of,localizations |
R691 |
T2605 |
T2606 |
det |
the,gene |
R692 |
T2606 |
T2604 |
pobj |
gene,of |
R693 |
T2607 |
T2606 |
compound |
mouse,gene |
R694 |
T2608 |
T2606 |
compound |
ESG1,gene |
R695 |
T2609 |
T2606 |
cc |
and,gene |
R696 |
T2610 |
T2606 |
conj |
pseudogenes,gene |
R697 |
T2611 |
T2603 |
punct |
", ",reported |
R698 |
T2612 |
T2603 |
advmod |
however,reported |
R699 |
T2613 |
T2603 |
punct |
", ",reported |
R700 |
T2614 |
T2603 |
aux |
have,reported |
R701 |
T2615 |
T2603 |
neg |
not,reported |
R702 |
T2616 |
T2603 |
auxpass |
been,reported |
R703 |
T2617 |
T2603 |
punct |
.,reported |
R704 |
T2619 |
T2620 |
prep |
In,determined |
R705 |
T2621 |
T2622 |
det |
this,study |
R706 |
T2622 |
T2619 |
pobj |
study,In |
R707 |
T2623 |
T2620 |
punct |
", ",determined |
R708 |
T2624 |
T2620 |
nsubj |
we,determined |
R709 |
T2625 |
T2626 |
det |
the,structure |
R710 |
T2626 |
T2620 |
dobj |
structure,determined |
R711 |
T2627 |
T2626 |
prep |
of,structure |
R712 |
T2628 |
T2629 |
det |
the,gene |
R713 |
T2629 |
T2627 |
pobj |
gene,of |
R714 |
T2630 |
T2629 |
compound |
mouse,gene |
R715 |
T2631 |
T2629 |
acl |
encoding,gene |
R716 |
T2632 |
T2633 |
det |
this,protein |
R717 |
T2633 |
T2631 |
dobj |
protein,encoding |
R718 |
T2634 |
T2633 |
cc |
and,protein |
R719 |
T2635 |
T2636 |
amod |
related,pseudogenes |
R720 |
T2636 |
T2633 |
conj |
pseudogenes,protein |
R721 |
T2637 |
T2620 |
punct |
.,determined |
R722 |
T2639 |
T2640 |
nsubj |
We,performed |
R723 |
T2641 |
T2640 |
advmod |
also,performed |
R724 |
T2642 |
T2643 |
compound |
gene,targeting |
R725 |
T2643 |
T2640 |
dobj |
targeting,performed |
R726 |
T2644 |
T2645 |
aux |
to,determine |
R727 |
T2645 |
T2640 |
advcl |
determine,performed |
R728 |
T2646 |
T2647 |
det |
the,function |
R729 |
T2647 |
T2645 |
dobj |
function,determine |
R730 |
T2648 |
T2647 |
amod |
physiological,function |
R731 |
T2649 |
T2647 |
prep |
of,function |
R732 |
T2650 |
T2649 |
pobj |
ESG1,of |
R733 |
T2651 |
T2640 |
punct |
.,performed |