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PMC:1420271 / 11837-12717 JSONTXT

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craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T6171 195-199 SO:0000704 denotes gene
T6172 234-238 PR:000006847 denotes ESG1
T6173 242-250 CL:0002322 denotes ES cells
T6174 268-278 GO:0010467 denotes expression
T6175 282-289 CL:0002322 denotes ES cell
T6176 297-302 SO:0000704 denotes genes
T6177 312-317 PR:000010968 denotes Nanog
T6178 322-326 PR:000013044 denotes Oct3
T6179 344-348 PR:000006847 denotes ESG1
T6180 352-360 CL:0002322 denotes ES cells
T6181 382-386 PR:000013044 denotes Oct3
T6182 389-399 GO:0010467 denotes expression
T6183 459-463 SO:0000704 denotes gene
T6184 459-474 GO:0010467 denotes gene expression
T6185 513-521 CL:0002322 denotes ES cells
T6186 526-530 PR:000006847 denotes ESG1
T6187 534-542 CL:0002322 denotes ES cells
T6188 552-557 SO:0000704 denotes genes
T6189 605-609 PR:000006847 denotes ESG1
T6190 630-634 PR:000009450 denotes Krt1
T6191 638-641 PR:000014397 denotes Pem
T6192 643-647 PR:000003172 denotes Ctgf
T6193 649-654 PR:000013428 denotes Ptgs2
T6194 665-670 PR:000000216 denotes Inhba
T6195 678-683 SO:0000704 denotes genes
T6196 693-702 GO:0065007 denotes regulated
T6197 729-733 PR:000006847 denotes ESG1
T6198 741-745 PR:000006847 denotes ESG1
T6199 777-783 SO:0000417 denotes domain
T6200 816-821 SO:0000704 denotes genes
T6162 3-4 CL:0002322 denotes e
T6163 4-5 CHEBI:51686 denotes x
T6164 16-20 SO:0000704 denotes gene
T6165 16-31 GO:0010467 denotes gene expression
T6166 44-48 PR:000006847 denotes ESG1
T6167 52-60 CL:0002322 denotes ES cells
T6168 126-131 SO:0000704 denotes genes
T6169 158-166 CL:0002322 denotes ES cells
T6170 168-172 PR:000006847 denotes ESG1

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T6307 0-1 SO_EXT:wild_type_entity_or_quality denotes W
T6327 240-241 SO_EXT:sequence_nullness_or_absence denotes -
T6328 242-250 CL:0002322 denotes ES cells
T6329 245-250 CL_GO_EXT:cell denotes cells
T6330 268-278 GO:0010467 denotes expression
T6331 282-289 CL:0002322 denotes ES cell
T6332 285-289 CL_GO_EXT:cell denotes cell
T6333 290-296 CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag denotes marker
T6334 297-302 SO_EXT:0000704 denotes genes
T6335 312-317 PR_EXT:000010968 denotes Nanog
T6336 322-326 PR_EXT:000013044 denotes Oct3
T6337 344-348 PR_EXT:000006847 denotes ESG1
T6338 348-349 SO_EXT:sequence_nullness_or_absence denotes -
T6339 350-351 SO_EXT:sequence_nullness_or_absence denotes -
T6340 352-360 CL:0002322 denotes ES cells
T6341 355-360 CL_GO_EXT:cell denotes cells
T6342 382-386 PR_EXT:000013044 denotes Oct3
T6343 389-399 GO:0010467 denotes expression
T6344 403-410 CHEBI_PR_EXT:protein denotes protein
T6345 459-463 SO_EXT:0000704 denotes gene
T6346 459-474 GO:0010467 denotes gene expression
T6347 513-521 CL:0002322 denotes ES cells
T6348 516-521 CL_GO_EXT:cell denotes cells
T6349 526-530 PR_EXT:000006847 denotes ESG1
T6350 530-531 SO_EXT:sequence_nullness_or_absence denotes -
T6351 532-533 SO_EXT:sequence_nullness_or_absence denotes -
T6352 534-542 CL:0002322 denotes ES cells
T6353 537-542 CL_GO_EXT:cell denotes cells
T6354 552-557 SO_EXT:0000704 denotes genes
T6355 605-609 PR_EXT:000006847 denotes ESG1
T6356 609-610 SO_EXT:sequence_nullness_or_absence denotes -
T6357 611-612 SO_EXT:sequence_nullness_or_absence denotes -
T6358 613-618 CL_GO_EXT:cell denotes cells
T6359 630-634 PR_EXT:000009450 denotes Krt1
T6360 638-641 PR_EXT:000014397 denotes Pem
T6361 643-647 PR_EXT:000003172 denotes Ctgf
T6362 649-654 PR_EXT:000013428 denotes Ptgs2
T6363 656-660 CHEBI_PR_EXT:insulin_like_growth_factor_2 denotes Igf2
T6364 665-670 PR_EXT:000000216 denotes Inhba
T6365 678-683 SO_EXT:0000704 denotes genes
T6366 693-702 GO:0065007 denotes regulated
T6367 729-733 PR_EXT:000006847 denotes ESG1
T6368 741-745 PR_EXT:000006847 denotes ESG1
T6369 765-768 CHEBI_SO_EXT:RNA denotes RNA
T6370 769-776 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes binding
T6371 777-783 SO_EXT:0000417 denotes domain
T6372 802-806 CHEBI_SO_EXT:mRNA denotes mRNA
T6373 816-821 SO_EXT:0000704 denotes genes
T6308 3-4 CL:0002322 denotes e
T6309 3-4 CL_GO_EXT:cell denotes e
T6310 4-5 CHEBI:51686 denotes x
T6311 16-20 SO_EXT:0000704 denotes gene
T6312 16-31 GO:0010467 denotes gene expression
T6313 44-48 PR_EXT:000006847 denotes ESG1
T6314 48-49 SO_EXT:sequence_nullness_or_absence denotes -
T6315 50-51 SO_EXT:sequence_nullness_or_absence denotes -
T6316 52-60 CL:0002322 denotes ES cells
T6317 55-60 CL_GO_EXT:cell denotes cells
T6318 67-82 CHEBI_SO_EXT:oligonucleotide denotes oligonucleotide
T6319 89-92 CHEBI_SO_EXT:DNA denotes DNA
T6320 126-131 SO_EXT:0000704 denotes genes
T6321 158-166 CL:0002322 denotes ES cells
T6322 161-166 CL_GO_EXT:cell denotes cells
T6323 168-172 PR_EXT:000006847 denotes ESG1
T6324 195-199 SO_EXT:0000704 denotes gene
T6325 234-238 PR_EXT:000006847 denotes ESG1
T6326 238-239 SO_EXT:sequence_nullness_or_absence denotes -

craft-sa-dev

Id Subject Object Predicate Lexical cue
T6815 49-50 HYPH denotes /
T6816 50-51 SYM denotes -
T6817 52-54 NN denotes ES
T6818 61-66 VBG denotes using
T6819 67-82 NN denotes oligonucleotide
T6820 83-88 VBN denotes based
T6821 82-83 HYPH denotes -
T6822 93-104 NNS denotes microarrays
T6823 89-92 NN denotes DNA
T6824 105-117 VBG denotes representing
T6825 118-119 SYM denotes ~
T6826 119-125 CD denotes 20,000
T6827 126-131 NNS denotes genes
T6828 131-132 . denotes .
T6829 132-263 sentence denotes In comparison to control ES cells, ESG1 was identified as the gene reduced to the greatest extent in ESG1-/- ES cells (Figure 6A).
T6830 133-135 IN denotes In
T6831 177-187 VBN denotes identified
T6832 136-146 NN denotes comparison
T6833 147-149 IN denotes to
T6834 150-157 NN denotes control
T6835 161-166 NNS denotes cells
T6836 158-160 NN denotes ES
T6837 166-168 , denotes ,
T6838 168-172 NN denotes ESG1
T6839 173-176 VBD denotes was
T6840 188-190 IN denotes as
T6841 191-194 DT denotes the
T6842 195-199 NN denotes gene
T6843 200-207 VBN denotes reduced
T6844 208-210 IN denotes to
T6845 211-214 DT denotes the
T6846 224-230 NN denotes extent
T6847 215-223 JJS denotes greatest
T6848 231-233 IN denotes in
T6849 234-238 NN denotes ESG1
T6850 245-250 NNS denotes cells
T6851 238-239 SYM denotes -
T6852 239-240 HYPH denotes /
T6853 240-241 SYM denotes -
T6854 242-244 NN denotes ES
T6855 251-252 -LRB- denotes (
T6856 259-261 NN denotes 6A
T6857 252-258 NN denotes Figure
T6858 261-262 -RRB- denotes )
T6859 262-263 . denotes .
T6860 263-361 sentence denotes The expression of ES cell marker genes, such as Nanog and Oct3/4, was normal in ESG1-/- ES cells.
T6861 264-267 DT denotes The
T6862 268-278 NN denotes expression
T6863 330-333 VBD denotes was
T6864 279-281 IN denotes of
T6865 282-284 NN denotes ES
T6866 285-289 NN denotes cell
T6867 297-302 NNS denotes genes
T6868 290-296 NN denotes marker
T6869 302-304 , denotes ,
T6870 304-308 JJ denotes such
T6871 309-311 IN denotes as
T6872 312-317 NN denotes Nanog
T6873 318-321 CC denotes and
T6874 322-326 NN denotes Oct3
T6875 326-327 HYPH denotes /
T6876 327-328 CD denotes 4
T6877 328-330 , denotes ,
T6878 334-340 JJ denotes normal
T6879 341-343 IN denotes in
T6880 344-348 NN denotes ESG1
T6881 355-360 NNS denotes cells
T6882 348-349 SYM denotes -
T6883 349-350 HYPH denotes /
T6884 350-351 SYM denotes -
T6885 352-354 NN denotes ES
T6886 360-361 . denotes .
T6887 361-446 sentence denotes We confirmed normal Oct3/4 expression at protein levels by Western blot (Figure 6B).
T6888 362-364 PRP denotes We
T6889 365-374 VBD denotes confirmed
T6890 375-381 JJ denotes normal
T6891 389-399 NN denotes expression
T6892 382-386 NN denotes Oct3
T6893 386-387 HYPH denotes /
T6894 387-388 CD denotes 4
T6895 400-402 IN denotes at
T6897 411-417 NNS denotes levels
T6898 418-420 IN denotes by
T6899 421-428 NNP denotes Western
T6900 429-433 NN denotes blot
T6901 434-435 -LRB- denotes (
T6902 442-444 NN denotes 6B
T6903 435-441 NN denotes Figure
T6904 444-445 -RRB- denotes )
T6905 445-446 . denotes .
T6906 446-543 sentence denotes The overall gene expression profiles were similar between control ES cells and ESG1-/- ES cells.
T6907 447-450 DT denotes The
T6908 475-483 NNS denotes profiles
T6909 451-458 JJ denotes overall
T6910 459-463 NN denotes gene
T6911 464-474 NN denotes expression
T6912 484-488 VBD denotes were
T6913 489-496 JJ denotes similar
T6914 497-504 IN denotes between
T6915 505-512 NN denotes control
T6916 516-521 NNS denotes cells
T6917 513-515 NN denotes ES
T6918 522-525 CC denotes and
T6919 526-530 NN denotes ESG1
T6920 537-542 NNS denotes cells
T6921 530-531 SYM denotes -
T6922 531-532 HYPH denotes /
T6923 532-533 SYM denotes -
T6924 534-536 NN denotes ES
T6925 542-543 . denotes .
T6926 543-671 sentence denotes Several genes exhibited a greater than two-fold reduction in ESG1-/- cells, including Krt1-8, Pem, Ctgf, Ptgs2, Igf2 and Inhba.
T6927 544-551 JJ denotes Several
T6928 552-557 NNS denotes genes
T6929 558-567 VBD denotes exhibited
T6930 568-569 DT denotes a
T6931 592-601 NN denotes reduction
T6932 570-577 JJR denotes greater
T6933 583-591 JJ denotes two-fold
T6934 578-582 IN denotes than
T6935 602-604 IN denotes in
T6936 605-609 NN denotes ESG1
T6937 613-618 NNS denotes cells
T6938 609-610 SYM denotes -
T6939 610-611 HYPH denotes /
T6940 611-612 SYM denotes -
T6941 618-620 , denotes ,
T6942 620-629 VBG denotes including
T6943 630-634 NN denotes Krt1
T6944 634-635 HYPH denotes -
T6945 635-636 CD denotes 8
T6946 636-638 , denotes ,
T6947 638-641 NN denotes Pem
T6948 641-643 , denotes ,
T6949 643-647 NN denotes Ctgf
T6950 647-649 , denotes ,
T6951 649-654 NN denotes Ptgs2
T6952 654-656 , denotes ,
T6953 656-660 NN denotes Igf2
T6954 661-664 CC denotes and
T6955 665-670 NN denotes Inhba
T6956 670-671 . denotes .
T6957 671-734 sentence denotes These genes might be regulated directly or indirectly by ESG1.
T6958 672-677 DT denotes These
T6959 678-683 NNS denotes genes
T6960 693-702 VBN denotes regulated
T6961 684-689 MD denotes might
T6962 690-692 VB denotes be
T6963 703-711 RB denotes directly
T6964 712-714 CC denotes or
T6965 715-725 RB denotes indirectly
T6966 726-728 IN denotes by
T6967 729-733 NN denotes ESG1
T6968 733-734 . denotes .
T6969 734-822 sentence denotes Since ESG1 contains a KH-type RNA-binding domain, it may stabilize mRNA of these genes.
T6970 735-740 IN denotes Since
T6971 746-754 VBZ denotes contains
T6972 741-745 NN denotes ESG1
T6973 792-801 VB denotes stabilize
T6974 755-756 DT denotes a
T6975 777-783 NN denotes domain
T6976 757-759 NN denotes KH
T6977 760-764 NN denotes type
T6978 759-760 HYPH denotes -
T6979 765-768 NN denotes RNA
T6980 769-776 VBG denotes binding
T6981 768-769 HYPH denotes -
T6982 783-785 , denotes ,
T6983 785-787 PRP denotes it
T6984 788-791 MD denotes may
T6985 802-806 NN denotes mRNA
T6986 807-809 IN denotes of
T6987 810-815 DT denotes these
T6988 816-821 NNS denotes genes
T6989 821-822 . denotes .
T6990 822-880 sentence denotes Further studied are required to clarify this possibility.
T6991 823-830 RB denotes Further
T6992 831-838 VBN denotes studied
T6993 843-851 VBN denotes required
T6994 839-842 VBP denotes are
T6995 852-854 TO denotes to
T6996 855-862 VB denotes clarify
T6997 863-867 DT denotes this
T6998 868-879 NN denotes possibility
T6999 879-880 . denotes .
T6798 0-4 sentence denotes We e
T6799 3-4 NNS denotes e
T6800 0-1 NN denotes W
T6801 1-2 JJ denotes e
T6802 4-6 sentence denotes xa
T6810 21-31 NN denotes expression
T6811 41-43 IN denotes of
T6812 44-48 NN denotes ESG1
T6813 55-60 NNS denotes cells
T6814 48-49 SYM denotes -
T6803 5-6 NN denotes a
T6804 4-5 NN denotes x
T6805 6-132 sentence denotes mined the gene expression profiles of ESG1-/- ES cells using oligonucleotide-based DNA microarrays representing ~20,000 genes.
T6806 6-11 VBD denotes mined
T6807 12-15 DT denotes the
T6808 32-40 NNS denotes profiles
T6809 16-20 NN denotes gene
T6896 403-410 NN denotes protein
R1653 T6822 T6818 dobj microarrays,using
R1654 T6823 T6822 compound DNA,microarrays
R1655 T6824 T6822 acl representing,microarrays
R1656 T6825 T6826 punct ~,"20,000"
R1657 T6826 T6827 nummod "20,000",genes
R1658 T6827 T6824 dobj genes,representing
R1659 T6828 T6806 punct .,mined
R1660 T6830 T6831 prep In,identified
R1661 T6832 T6830 pobj comparison,In
R1662 T6833 T6832 prep to,comparison
R1663 T6834 T6835 compound control,cells
R1664 T6835 T6833 pobj cells,to
R1665 T6836 T6835 compound ES,cells
R1666 T6837 T6831 punct ", ",identified
R1667 T6838 T6831 nsubjpass ESG1,identified
R1668 T6839 T6831 auxpass was,identified
R1669 T6840 T6831 prep as,identified
R1670 T6841 T6842 det the,gene
R1671 T6842 T6840 pobj gene,as
R1672 T6843 T6842 acl reduced,gene
R1673 T6844 T6843 prep to,reduced
R1674 T6845 T6846 det the,extent
R1675 T6846 T6844 pobj extent,to
R1676 T6847 T6846 amod greatest,extent
R1677 T6848 T6843 prep in,reduced
R1678 T6849 T6850 nmod ESG1,cells
R1679 T6850 T6848 pobj cells,in
R1680 T6851 T6849 punct -,ESG1
R1681 T6852 T6849 punct /,ESG1
R1682 T6853 T6849 punct -,ESG1
R1683 T6854 T6850 compound ES,cells
R1684 T6855 T6856 punct (,6A
R1685 T6856 T6842 parataxis 6A,gene
R1686 T6857 T6856 compound Figure,6A
R1687 T6858 T6856 punct ),6A
R1688 T6859 T6831 punct .,identified
R1689 T6861 T6862 det The,expression
R1690 T6862 T6863 nsubj expression,was
R1691 T6864 T6862 prep of,expression
R1692 T6865 T6866 compound ES,cell
R1693 T6866 T6867 compound cell,genes
R1694 T6867 T6864 pobj genes,of
R1695 T6868 T6867 compound marker,genes
R1696 T6869 T6867 punct ", ",genes
R1697 T6870 T6871 amod such,as
R1698 T6871 T6867 prep as,genes
R1699 T6872 T6871 pobj Nanog,as
R1700 T6873 T6872 cc and,Nanog
R1701 T6874 T6872 conj Oct3,Nanog
R1702 T6875 T6874 punct /,Oct3
R1703 T6876 T6874 nummod 4,Oct3
R1704 T6877 T6863 punct ", ",was
R1705 T6878 T6863 acomp normal,was
R1706 T6879 T6863 prep in,was
R1707 T6880 T6881 nmod ESG1,cells
R1708 T6881 T6879 pobj cells,in
R1709 T6882 T6880 punct -,ESG1
R1710 T6883 T6880 punct /,ESG1
R1711 T6884 T6880 punct -,ESG1
R1712 T6885 T6881 compound ES,cells
R1713 T6886 T6863 punct .,was
R1714 T6888 T6889 nsubj We,confirmed
R1715 T6890 T6891 amod normal,expression
R1716 T6891 T6889 dobj expression,confirmed
R1717 T6892 T6891 nmod Oct3,expression
R1718 T6893 T6892 punct /,Oct3
R1719 T6894 T6892 nummod 4,Oct3
R1720 T6895 T6891 prep at,expression
R1721 T6896 T6897 compound protein,levels
R1722 T6897 T6895 pobj levels,at
R1723 T6898 T6889 prep by,confirmed
R1724 T6899 T6900 compound Western,blot
R1725 T6900 T6898 pobj blot,by
R1726 T6901 T6902 punct (,6B
R1727 T6902 T6889 parataxis 6B,confirmed
R1728 T6903 T6902 compound Figure,6B
R1729 T6904 T6902 punct ),6B
R1730 T6905 T6889 punct .,confirmed
R1731 T6907 T6908 det The,profiles
R1732 T6908 T6912 nsubj profiles,were
R1733 T6909 T6908 amod overall,profiles
R1734 T6910 T6911 compound gene,expression
R1735 T6911 T6908 compound expression,profiles
R1736 T6913 T6912 acomp similar,were
R1737 T6914 T6912 prep between,were
R1738 T6915 T6916 compound control,cells
R1739 T6916 T6914 pobj cells,between
R1740 T6917 T6916 compound ES,cells
R1741 T6918 T6916 cc and,cells
R1742 T6919 T6920 nmod ESG1,cells
R1743 T6920 T6916 conj cells,cells
R1744 T6921 T6919 punct -,ESG1
R1745 T6922 T6919 punct /,ESG1
R1746 T6923 T6919 punct -,ESG1
R1747 T6924 T6920 compound ES,cells
R1748 T6925 T6912 punct .,were
R1749 T6927 T6928 amod Several,genes
R1750 T6928 T6929 nsubj genes,exhibited
R1751 T6930 T6931 det a,reduction
R1752 T6931 T6929 dobj reduction,exhibited
R1753 T6932 T6933 amod greater,two-fold
R1754 T6933 T6931 nummod two-fold,reduction
R1755 T6934 T6933 quantmod than,two-fold
R1756 T6935 T6929 prep in,exhibited
R1757 T6936 T6937 nmod ESG1,cells
R1758 T6937 T6935 pobj cells,in
R1759 T6938 T6936 punct -,ESG1
R1760 T6939 T6936 punct /,ESG1
R1761 T6940 T6936 punct -,ESG1
R1762 T6941 T6929 punct ", ",exhibited
R1763 T6942 T6929 prep including,exhibited
R1764 T6943 T6942 pobj Krt1,including
R1765 T6944 T6943 punct -,Krt1
R1766 T6945 T6943 nummod 8,Krt1
R1767 T6946 T6943 punct ", ",Krt1
R1768 T6947 T6943 conj Pem,Krt1
R1769 T6948 T6947 punct ", ",Pem
R1770 T6949 T6947 conj Ctgf,Pem
R1771 T6950 T6949 punct ", ",Ctgf
R1772 T6951 T6949 conj Ptgs2,Ctgf
R1773 T6952 T6951 punct ", ",Ptgs2
R1774 T6953 T6951 conj Igf2,Ptgs2
R1775 T6954 T6953 cc and,Igf2
R1776 T6955 T6953 conj Inhba,Igf2
R1777 T6956 T6929 punct .,exhibited
R1778 T6958 T6959 det These,genes
R1779 T6959 T6960 nsubjpass genes,regulated
R1780 T6961 T6960 aux might,regulated
R1781 T6962 T6960 auxpass be,regulated
R1782 T6963 T6960 advmod directly,regulated
R1637 T6804 T6803 nmod x,a
R1638 T6807 T6808 det the,profiles
R1639 T6808 T6806 dobj profiles,mined
R1640 T6809 T6808 compound gene,profiles
R1641 T6810 T6808 compound expression,profiles
R1642 T6811 T6808 prep of,profiles
R1643 T6812 T6813 nmod ESG1,cells
R1644 T6813 T6811 pobj cells,of
R1645 T6814 T6812 punct -,ESG1
R1646 T6815 T6812 punct /,ESG1
R1647 T6816 T6812 punct -,ESG1
R1648 T6817 T6813 compound ES,cells
R1649 T6818 T6806 advcl using,mined
R1650 T6819 T6820 npadvmod oligonucleotide,based
R1651 T6820 T6822 amod based,microarrays
R1652 T6821 T6820 punct -,based
R1783 T6964 T6963 cc or,directly
R1784 T6965 T6963 conj indirectly,directly
R1785 T6966 T6960 agent by,regulated
R1786 T6967 T6966 pobj ESG1,by
R1787 T6968 T6960 punct .,regulated
R1788 T6970 T6971 mark Since,contains
R1789 T6971 T6973 advcl contains,stabilize
R1790 T6972 T6971 nsubj ESG1,contains
R1791 T6974 T6975 det a,domain
R1792 T6975 T6971 dobj domain,contains
R1793 T6976 T6977 nmod KH,type
R1794 T6977 T6975 nmod type,domain
R1795 T6978 T6977 punct -,type
R1796 T6979 T6980 npadvmod RNA,binding
R1797 T6980 T6975 amod binding,domain
R1798 T6981 T6980 punct -,binding
R1799 T6982 T6973 punct ", ",stabilize
R1800 T6983 T6973 nsubj it,stabilize
R1801 T6984 T6973 aux may,stabilize
R1802 T6985 T6973 dobj mRNA,stabilize
R1803 T6986 T6985 prep of,mRNA
R1804 T6987 T6988 det these,genes
R1805 T6988 T6986 pobj genes,of
R1806 T6989 T6973 punct .,stabilize
R1807 T6991 T6992 advmod Further,studied
R1808 T6992 T6993 nsubjpass studied,required
R1809 T6994 T6993 auxpass are,required
R1810 T6995 T6996 aux to,clarify
R1811 T6996 T6993 advcl clarify,required
R1812 T6997 T6998 det this,possibility
R1813 T6998 T6996 dobj possibility,clarify
R1814 T6999 T6993 punct .,required