PMC:1382200 / 403-652 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1382200","sourcedb":"PMC","sourceid":"1382200","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1382200","text":"nit encoded by Capn4. Disruption of the mouse Capn4 gene abolished both μ-calpain and m-calpain activity, and resulted in embryonic lethality, thereby suggesting essential roles for one or both of these enzymes during mammalian embryogenesis. Disrup","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T739","span":{"begin":4,"end":11},"obj":"VBN"},{"id":"T740","span":{"begin":12,"end":14},"obj":"IN"},{"id":"T741","span":{"begin":15,"end":20},"obj":"NN"},{"id":"T742","span":{"begin":20,"end":21},"obj":"."},{"id":"T743","span":{"begin":21,"end":242},"obj":"sentence"},{"id":"T744","span":{"begin":22,"end":32},"obj":"NN"},{"id":"T745","span":{"begin":57,"end":66},"obj":"VBD"},{"id":"T746","span":{"begin":33,"end":35},"obj":"IN"},{"id":"T747","span":{"begin":36,"end":39},"obj":"DT"},{"id":"T748","span":{"begin":52,"end":56},"obj":"NN"},{"id":"T749","span":{"begin":40,"end":45},"obj":"NN"},{"id":"T750","span":{"begin":46,"end":51},"obj":"NN"},{"id":"T751","span":{"begin":67,"end":71},"obj":"CC"},{"id":"T752","span":{"begin":74,"end":81},"obj":"NN"},{"id":"T753","span":{"begin":72,"end":73},"obj":"NN"},{"id":"T754","span":{"begin":73,"end":74},"obj":"HYPH"},{"id":"T755","span":{"begin":96,"end":104},"obj":"NN"},{"id":"T756","span":{"begin":82,"end":85},"obj":"CC"},{"id":"T757","span":{"begin":86,"end":87},"obj":"NN"},{"id":"T758","span":{"begin":88,"end":95},"obj":"NN"},{"id":"T759","span":{"begin":87,"end":88},"obj":"HYPH"},{"id":"T760","span":{"begin":104,"end":106},"obj":","},{"id":"T761","span":{"begin":106,"end":109},"obj":"CC"},{"id":"T762","span":{"begin":110,"end":118},"obj":"VBD"},{"id":"T763","span":{"begin":119,"end":121},"obj":"IN"},{"id":"T764","span":{"begin":122,"end":131},"obj":"JJ"},{"id":"T765","span":{"begin":132,"end":141},"obj":"NN"},{"id":"T766","span":{"begin":141,"end":143},"obj":","},{"id":"T767","span":{"begin":143,"end":150},"obj":"RB"},{"id":"T768","span":{"begin":151,"end":161},"obj":"VBG"},{"id":"T769","span":{"begin":162,"end":171},"obj":"JJ"},{"id":"T770","span":{"begin":172,"end":177},"obj":"NNS"},{"id":"T771","span":{"begin":178,"end":181},"obj":"IN"},{"id":"T772","span":{"begin":182,"end":185},"obj":"CD"},{"id":"T773","span":{"begin":186,"end":188},"obj":"CC"},{"id":"T774","span":{"begin":189,"end":193},"obj":"DT"},{"id":"T775","span":{"begin":194,"end":196},"obj":"IN"},{"id":"T776","span":{"begin":197,"end":202},"obj":"DT"},{"id":"T777","span":{"begin":203,"end":210},"obj":"NNS"},{"id":"T778","span":{"begin":211,"end":217},"obj":"IN"},{"id":"T779","span":{"begin":218,"end":227},"obj":"JJ"},{"id":"T780","span":{"begin":228,"end":241},"obj":"NN"},{"id":"T781","span":{"begin":241,"end":242},"obj":"."}],"relations":[{"id":"R73","pred":"det","subj":"T747","obj":"T748"},{"id":"R74","pred":"pobj","subj":"T748","obj":"T746"},{"id":"R68","pred":"agent","subj":"T740","obj":"T739"},{"id":"R69","pred":"pobj","subj":"T741","obj":"T740"},{"id":"R71","pred":"nsubj","subj":"T744","obj":"T745"},{"id":"R72","pred":"prep","subj":"T746","obj":"T744"},{"id":"R75","pred":"compound","subj":"T749","obj":"T748"},{"id":"R76","pred":"compound","subj":"T750","obj":"T748"},{"id":"R77","pred":"preconj","subj":"T751","obj":"T752"},{"id":"R78","pred":"nmod","subj":"T752","obj":"T755"},{"id":"R79","pred":"nmod","subj":"T753","obj":"T752"},{"id":"R80","pred":"punct","subj":"T754","obj":"T752"},{"id":"R81","pred":"dobj","subj":"T755","obj":"T745"},{"id":"R82","pred":"cc","subj":"T756","obj":"T752"},{"id":"R83","pred":"compound","subj":"T757","obj":"T758"},{"id":"R84","pred":"conj","subj":"T758","obj":"T752"},{"id":"R85","pred":"punct","subj":"T759","obj":"T758"},{"id":"R86","pred":"punct","subj":"T760","obj":"T745"},{"id":"R87","pred":"cc","subj":"T761","obj":"T745"},{"id":"R88","pred":"conj","subj":"T762","obj":"T745"},{"id":"R89","pred":"prep","subj":"T763","obj":"T762"},{"id":"R90","pred":"amod","subj":"T764","obj":"T765"},{"id":"R91","pred":"pobj","subj":"T765","obj":"T763"},{"id":"R92","pred":"punct","subj":"T766","obj":"T762"},{"id":"R93","pred":"advmod","subj":"T767","obj":"T768"},{"id":"R94","pred":"advcl","subj":"T768","obj":"T762"},{"id":"R95","pred":"amod","subj":"T769","obj":"T770"},{"id":"R96","pred":"dobj","subj":"T770","obj":"T768"},{"id":"R97","pred":"prep","subj":"T771","obj":"T770"},{"id":"R98","pred":"pobj","subj":"T772","obj":"T771"},{"id":"R99","pred":"cc","subj":"T773","obj":"T772"},{"id":"R100","pred":"conj","subj":"T774","obj":"T772"},{"id":"R101","pred":"prep","subj":"T775","obj":"T772"},{"id":"R102","pred":"det","subj":"T776","obj":"T777"},{"id":"R103","pred":"pobj","subj":"T777","obj":"T775"},{"id":"R104","pred":"prep","subj":"T778","obj":"T770"},{"id":"R105","pred":"amod","subj":"T779","obj":"T780"},{"id":"R106","pred":"pobj","subj":"T780","obj":"T778"},{"id":"R107","pred":"punct","subj":"T781","obj":"T745"}],"attributes":[{"subj":"T739","pred":"source","obj":"craft-sa-dev"},{"subj":"T740","pred":"source","obj":"craft-sa-dev"},{"subj":"T741","pred":"source","obj":"craft-sa-dev"},{"subj":"T742","pred":"source","obj":"craft-sa-dev"},{"subj":"T743","pred":"source","obj":"craft-sa-dev"},{"subj":"T744","pred":"source","obj":"craft-sa-dev"},{"subj":"T745","pred":"source","obj":"craft-sa-dev"},{"subj":"T746","pred":"source","obj":"craft-sa-dev"},{"subj":"T747","pred":"source","obj":"craft-sa-dev"},{"subj":"T748","pred":"source","obj":"craft-sa-dev"},{"subj":"T749","pred":"source","obj":"craft-sa-dev"},{"subj":"T750","pred":"source","obj":"craft-sa-dev"},{"subj":"T751","pred":"source","obj":"craft-sa-dev"},{"subj":"T752","pred":"source","obj":"craft-sa-dev"},{"subj":"T753","pred":"source","obj":"craft-sa-dev"},{"subj":"T754","pred":"source","obj":"craft-sa-dev"},{"subj":"T755","pred":"source","obj":"craft-sa-dev"},{"subj":"T756","pred":"source","obj":"craft-sa-dev"},{"subj":"T757","pred":"source","obj":"craft-sa-dev"},{"subj":"T758","pred":"source","obj":"craft-sa-dev"},{"subj":"T759","pred":"source","obj":"craft-sa-dev"},{"subj":"T760","pred":"source","obj":"craft-sa-dev"},{"subj":"T761","pred":"source","obj":"craft-sa-dev"},{"subj":"T762","pred":"source","obj":"craft-sa-dev"},{"subj":"T763","pred":"source","obj":"craft-sa-dev"},{"subj":"T764","pred":"source","obj":"craft-sa-dev"},{"subj":"T765","pred":"source","obj":"craft-sa-dev"},{"subj":"T766","pred":"source","obj":"craft-sa-dev"},{"subj":"T767","pred":"source","obj":"craft-sa-dev"},{"subj":"T768","pred":"source","obj":"craft-sa-dev"},{"subj":"T769","pred":"source","obj":"craft-sa-dev"},{"subj":"T770","pred":"source","obj":"craft-sa-dev"},{"subj":"T771","pred":"source","obj":"craft-sa-dev"},{"subj":"T772","pred":"source","obj":"craft-sa-dev"},{"subj":"T773","pred":"source","obj":"craft-sa-dev"},{"subj":"T774","pred":"source","obj":"craft-sa-dev"},{"subj":"T775","pred":"source","obj":"craft-sa-dev"},{"subj":"T776","pred":"source","obj":"craft-sa-dev"},{"subj":"T777","pred":"source","obj":"craft-sa-dev"},{"subj":"T778","pred":"source","obj":"craft-sa-dev"},{"subj":"T779","pred":"source","obj":"craft-sa-dev"},{"subj":"T780","pred":"source","obj":"craft-sa-dev"},{"subj":"T781","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T544","span":{"begin":15,"end":20},"obj":"PR:000005022"},{"id":"T545","span":{"begin":40,"end":45},"obj":"NCBITaxon:10088"},{"id":"T546","span":{"begin":46,"end":51},"obj":"PR:000005022"},{"id":"T547","span":{"begin":52,"end":56},"obj":"SO:0000704"},{"id":"T548","span":{"begin":122,"end":131},"obj":"UBERON:0000922"},{"id":"T549","span":{"begin":218,"end":227},"obj":"NCBITaxon:40674"},{"id":"T550","span":{"begin":228,"end":241},"obj":"GO:0009790"}],"attributes":[{"subj":"T544","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T545","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T546","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T547","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T548","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T549","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T550","pred":"source","obj":"craft-ca-core-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T606","span":{"begin":4,"end":11},"obj":"SO_EXT:sequence_coding_function"},{"id":"T607","span":{"begin":15,"end":20},"obj":"PR_EXT:000005022"},{"id":"T608","span":{"begin":40,"end":45},"obj":"NCBITaxon:10088"},{"id":"T609","span":{"begin":46,"end":51},"obj":"PR_EXT:000005022"},{"id":"T610","span":{"begin":52,"end":56},"obj":"SO_EXT:0000704"},{"id":"T611","span":{"begin":72,"end":81},"obj":"GO_PR_EXT:calpain_1_complex"},{"id":"T612","span":{"begin":86,"end":95},"obj":"GO_PR_EXT:calpain_2_complex"},{"id":"T613","span":{"begin":122,"end":131},"obj":"UBERON:0000922"},{"id":"T614","span":{"begin":132,"end":141},"obj":"GO_EXT:fatality_or_lethality"},{"id":"T615","span":{"begin":203,"end":210},"obj":"CHEBI_GO_SO_EXT:enzyme"},{"id":"T616","span":{"begin":218,"end":227},"obj":"NCBITaxon:40674"},{"id":"T617","span":{"begin":228,"end":241},"obj":"GO:0009790"}],"attributes":[{"subj":"T606","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T607","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T608","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T609","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T610","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T611","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T612","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T613","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T614","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T615","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T616","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T617","pred":"source","obj":"craft-ca-core-ex-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#93ecb7","default":true},{"id":"craft-ca-core-dev","color":"#ec9d93"},{"id":"craft-ca-core-ex-dev","color":"#93a2ec"}]}]}}