PMC:1359074 / 18147-18697 JSON TXT

Annnotations TAB JSON ListView MergeView

2_test

{"project":"2_test","denotations":[{"id":"16462943-283312-85760997","span":{"begin":172,"end":174},"obj":"283312"},{"id":"T6698","span":{"begin":172,"end":174},"obj":"283312"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

pmc-enju-pas

bionlp-st-ge-2016-coref

{"project":"bionlp-st-ge-2016-coref","denotations":[{"id":"T7235","span":{"begin":200,"end":217},"obj":"Anaphor"}],"namespaces":[{"prefix":"_base","uri":"https://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

bionlp-st-ge-2016-test-proteins

{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T7260","span":{"begin":177,"end":181},"obj":"Protein"},{"id":"T7259","span":{"begin":168,"end":170},"obj":"Protein"},{"id":"T7258","span":{"begin":149,"end":158},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

bionlp-st-ge-2016-uniprot

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T7979","span":{"begin":407,"end":411},"obj":"http://www.uniprot.org/uniprot/P35712"},{"id":"T7978","span":{"begin":269,"end":273},"obj":"http://www.uniprot.org/uniprot/P35712"},{"id":"T7977","span":{"begin":177,"end":181},"obj":"http://www.uniprot.org/uniprot/P35712"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

GO-BP

{"project":"GO-BP","denotations":[{"id":"T7168","span":{"begin":151,"end":158},"obj":"http://purl.obolibrary.org/obo/GO_0005344"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

GO-MF

{"project":"GO-MF","denotations":[{"id":"T7289","span":{"begin":151,"end":158},"obj":"http://purl.obolibrary.org/obo/GO_0005344"},{"id":"T7281","span":{"begin":542,"end":549},"obj":"http://purl.obolibrary.org/obo/GO_0005488"},{"id":"T7280","span":{"begin":412,"end":419},"obj":"http://purl.obolibrary.org/obo/GO_0005488"},{"id":"T7279","span":{"begin":326,"end":333},"obj":"http://purl.obolibrary.org/obo/GO_0005488"},{"id":"T7278","span":{"begin":274,"end":281},"obj":"http://purl.obolibrary.org/obo/GO_0005488"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

GO-CC

{"project":"GO-CC","denotations":[{"id":"T7298","span":{"begin":225,"end":230},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T7297","span":{"begin":92,"end":97},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T7296","span":{"begin":32,"end":37},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

sentences

{"project":"sentences","denotations":[{"id":"T7157","span":{"begin":492,"end":550},"obj":"Sentence"},{"id":"T7156","span":{"begin":382,"end":491},"obj":"Sentence"},{"id":"T7155","span":{"begin":244,"end":381},"obj":"Sentence"},{"id":"T7154","span":{"begin":177,"end":243},"obj":"Sentence"},{"id":"T7153","span":{"begin":88,"end":176},"obj":"Sentence"},{"id":"T7152","span":{"begin":0,"end":87},"obj":"Sentence"},{"id":"T128","span":{"begin":0,"end":87},"obj":"Sentence"},{"id":"T129","span":{"begin":88,"end":176},"obj":"Sentence"},{"id":"T130","span":{"begin":177,"end":243},"obj":"Sentence"},{"id":"T131","span":{"begin":244,"end":381},"obj":"Sentence"},{"id":"T132","span":{"begin":382,"end":491},"obj":"Sentence"},{"id":"T133","span":{"begin":492,"end":550},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

simple1

{"project":"simple1","denotations":[{"id":"T7418","span":{"begin":177,"end":181},"obj":"Protein"},{"id":"T7417","span":{"begin":168,"end":170},"obj":"Protein"},{"id":"T7416","span":{"begin":149,"end":158},"obj":"Protein"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

BioNLP16_DUT

{"project":"BioNLP16_DUT","denotations":[{"id":"T8903","span":{"begin":191,"end":196},"obj":"Binding"},{"id":"T8902","span":{"begin":135,"end":142},"obj":"Gene_expression"},{"id":"T8880","span":{"begin":177,"end":181},"obj":"Protein"},{"id":"T8879","span":{"begin":168,"end":170},"obj":"Protein"},{"id":"T8878","span":{"begin":149,"end":158},"obj":"Protein"}],"relations":[{"id":"R6211","pred":"themeOf","subj":"T8878","obj":"T8902"},{"id":"R6212","pred":"themeOf","subj":"T8880","obj":"T8903"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

BioNLP16_Messiy

{"project":"BioNLP16_Messiy","denotations":[{"id":"T8033","span":{"begin":191,"end":196},"obj":"Binding"},{"id":"T8032","span":{"begin":135,"end":142},"obj":"Gene_expression"},{"id":"T8011","span":{"begin":177,"end":181},"obj":"Protein"},{"id":"T8010","span":{"begin":168,"end":170},"obj":"Protein"},{"id":"T8009","span":{"begin":149,"end":158},"obj":"Protein"}],"relations":[{"id":"R5551","pred":"themeOf","subj":"T8010","obj":"T8032"},{"id":"R5552","pred":"themeOf","subj":"T8011","obj":"T8033"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

DLUT931

{"project":"DLUT931","denotations":[{"id":"T8085","span":{"begin":191,"end":196},"obj":"Binding"},{"id":"T8084","span":{"begin":135,"end":142},"obj":"Gene_expression"},{"id":"T8060","span":{"begin":177,"end":181},"obj":"Protein"},{"id":"T8059","span":{"begin":168,"end":170},"obj":"Protein"},{"id":"T8058","span":{"begin":149,"end":158},"obj":"Protein"}],"relations":[{"id":"R5568","pred":"themeOf","subj":"T8058","obj":"T8084"},{"id":"R5569","pred":"themeOf","subj":"T8059","obj":"T8084"},{"id":"R5570","pred":"themeOf","subj":"T8060","obj":"T8085"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

bionlp-st-ge-2016-test-ihmc

{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T8858","span":{"begin":394,"end":445},"obj":"Binding"},{"id":"T8855","span":{"begin":244,"end":304},"obj":"Binding"},{"id":"T8853","span":{"begin":177,"end":242},"obj":"Binding"},{"id":"T8848","span":{"begin":534,"end":549},"obj":"Binding"},{"id":"T8840","span":{"begin":282,"end":287},"obj":"Entity"},{"id":"T8838","span":{"begin":427,"end":429},"obj":"Entity"},{"id":"T8832","span":{"begin":403,"end":411},"obj":"Protein"},{"id":"T8827","span":{"begin":407,"end":411},"obj":"Protein"},{"id":"T8824","span":{"begin":168,"end":175},"obj":"Protein"},{"id":"T8823","span":{"begin":420,"end":437},"obj":"Entity"},{"id":"T8820","span":{"begin":347,"end":380},"obj":"Entity"},{"id":"T8816","span":{"begin":205,"end":208},"obj":"Entity"},{"id":"T8796","span":{"begin":291,"end":304},"obj":"Entity"},{"id":"T8795","span":{"begin":244,"end":304},"obj":"Protein"},{"id":"T8777","span":{"begin":143,"end":175},"obj":"Protein"},{"id":"T8774","span":{"begin":177,"end":181},"obj":"Protein"},{"id":"T8772","span":{"begin":496,"end":498},"obj":"Entity"},{"id":"T8757","span":{"begin":403,"end":411},"obj":"Protein"}],"relations":[{"id":"R6170","pred":"themeOf","subj":"T8757","obj":"T8858"},{"id":"R6181","pred":"themeOf","subj":"T8774","obj":"T8853"},{"id":"R6192","pred":"themeOf","subj":"T8795","obj":"T8855"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

bionlp-st-ge-2016-spacy-parsed

bionlp-st-ge-2016-test-tees

{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T7371","span":{"begin":403,"end":406},"obj":"Protein"},{"id":"T7370","span":{"begin":309,"end":317},"obj":"Positive_regulation"},{"id":"T7369","span":{"begin":309,"end":317},"obj":"Positive_regulation"},{"id":"T7368","span":{"begin":326,"end":333},"obj":"Binding"},{"id":"T7367","span":{"begin":326,"end":333},"obj":"Binding"},{"id":"T7366","span":{"begin":269,"end":273},"obj":"Protein"},{"id":"T7365","span":{"begin":265,"end":268},"obj":"Protein"},{"id":"T7364","span":{"begin":191,"end":196},"obj":"Binding"},{"id":"T7363","span":{"begin":177,"end":181},"obj":"Protein"},{"id":"T7362","span":{"begin":135,"end":142},"obj":"Gene_expression"},{"id":"T7361","span":{"begin":143,"end":158},"obj":"Protein"},{"id":"T7378","span":{"begin":542,"end":549},"obj":"Binding"},{"id":"T7377","span":{"begin":539,"end":541},"obj":"Protein"},{"id":"T7376","span":{"begin":438,"end":445},"obj":"Negative_regulation"},{"id":"T7375","span":{"begin":438,"end":445},"obj":"Negative_regulation"},{"id":"T7374","span":{"begin":463,"end":470},"obj":"Binding"},{"id":"T7373","span":{"begin":463,"end":470},"obj":"Binding"},{"id":"T7372","span":{"begin":407,"end":411},"obj":"Protein"}],"relations":[{"id":"R4988","pred":"themeOf","subj":"T7361","obj":"T7362"},{"id":"R4989","pred":"themeOf","subj":"T7363","obj":"T7364"},{"id":"R4990","pred":"themeOf","subj":"T7365","obj":"T7367"},{"id":"R4991","pred":"themeOf","subj":"T7366","obj":"T7368"},{"id":"R4992","pred":"themeOf","subj":"T7367","obj":"T7369"},{"id":"R4993","pred":"themeOf","subj":"T7368","obj":"T7370"},{"id":"R4994","pred":"themeOf","subj":"T7371","obj":"T7373"},{"id":"R4995","pred":"themeOf","subj":"T7372","obj":"T7374"},{"id":"R4996","pred":"themeOf","subj":"T7373","obj":"T7375"},{"id":"R4997","pred":"themeOf","subj":"T7374","obj":"T7376"},{"id":"R4998","pred":"themeOf","subj":"T7377","obj":"T7378"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

testone

{"project":"testone","denotations":[{"id":"T7052","span":{"begin":542,"end":549},"obj":"Binding"},{"id":"T7051","span":{"begin":326,"end":333},"obj":"Binding"},{"id":"T7050","span":{"begin":309,"end":317},"obj":"Positive_regulation"},{"id":"T7049","span":{"begin":191,"end":196},"obj":"Binding"},{"id":"T7048","span":{"begin":135,"end":142},"obj":"Gene_expression"},{"id":"T7023","span":{"begin":177,"end":181},"obj":"Protein"},{"id":"T7022","span":{"begin":168,"end":170},"obj":"Protein"},{"id":"T7021","span":{"begin":149,"end":158},"obj":"Protein"}],"relations":[{"id":"R4904","pred":"themeOf","subj":"T7021","obj":"T7048"},{"id":"R4905","pred":"themeOf","subj":"T7022","obj":"T7048"},{"id":"R4906","pred":"themeOf","subj":"T7023","obj":"T7049"},{"id":"R4912","pred":"themeOf","subj":"T7051","obj":"T7050"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

test3

{"project":"test3","denotations":[{"id":"T7121","span":{"begin":191,"end":196},"obj":"Binding"},{"id":"T7120","span":{"begin":177,"end":181},"obj":"Protein"},{"id":"T7119","span":{"begin":168,"end":170},"obj":"Protein"},{"id":"T7118","span":{"begin":149,"end":158},"obj":"Protein"},{"id":"T7079","span":{"begin":177,"end":181},"obj":"Protein"},{"id":"T7078","span":{"begin":168,"end":170},"obj":"Protein"},{"id":"T7077","span":{"begin":149,"end":158},"obj":"Protein"}],"relations":[{"id":"R4930","pred":"themeOf","subj":"T7120","obj":"T7121"}],"text":"Next, nuclear extracts from MEL cells were used in EMSA employing the same 36-bp probe. MEL cells, a murine erythroleukemic cell line, express adult β globins, but not ɛy [33]. Sox6 directly binds to this DNA sequence in MEL cells (Figure 3D). The intact consensus Sox/Sox6 binding sites of the DNA probe are required for the binding, as shown in the competition assay (Figure 3E). Ablation of putative Sox/Sox6 binding sites (M1 and M3) abolish their ability to compete in EMSA (Figure 3E). The M2 mutant probe may compete partially with WT binding."}

PMC:1359074 / 18147-18697 JSONTXT

Annnotations TAB JSON ListView MergeView

PMC:1359074 / 18147-18697 JSON TXT