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results support the hypothesis that each of the antioxidant or DNA repair genes correlated with CEBPG in non-BC individuals is regulated by CEBPG. This is supported by the specificity of the CEBPG correlation. That is, there was lack of correlation between any of the other five transcription factors assessed and these target genes. Of particular note is the lack of correlation of the target genes with CEBPB, which binds to the same recognition site as CEBPG, and shares its recognition site within each of the antioxidant or DNA repair genes. However, there are alternative explanations for the observed correlation of CEBPG with antioxidant and DNA repair genes in non-BC individuals. One possibility is that CEBPG and each of the correlated antioxidant or DNA repair genes is regulated by a transcription factor that is as yet undiscovered, and/or has a recognition site that is not yet known and was not in the Genomatix software database."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T3736","span":{"begin":54,"end":65},"obj":"CHEBI_GO_EXT:antioxidant"},{"id":"T3737","span":{"begin":58,"end":65},"obj":"CHEBI_MOP_EXT:oxidising_agent_or_oxidation"},{"id":"T3738","span":{"begin":69,"end":72},"obj":"CHEBI_SO_EXT:DNA"},{"id":"T3739","span":{"begin":69,"end":79},"obj":"GO:0006281"},{"id":"T3740","span":{"begin":80,"end":85},"obj":"SO_EXT:0000704"},{"id":"T3741","span":{"begin":102,"end":107},"obj":"PR_EXT:000005311"},{"id":"T3742","span":{"begin":118,"end":129},"obj":"NCBITaxon:1"},{"id":"T3743","span":{"begin":133,"end":142},"obj":"GO:0065007"},{"id":"T3744","span":{"begin":146,"end":151},"obj":"PR_EXT:000005311"},{"id":"T3745","span":{"begin":197,"end":202},"obj":"PR_EXT:000005311"},{"id":"T3746","span":{"begin":285,"end":298},"obj":"GO_EXT:transcription"},{"id":"T3747","span":{"begin":285,"end":306},"obj":"GO_EXT:transcription_factor"},{"id":"T3748","span":{"begin":333,"end":338},"obj":"SO_EXT:0000704"},{"id":"T3749","span":{"begin":400,"end":405},"obj":"SO_EXT:0000704"},{"id":"T3750","span":{"begin":411,"end":416},"obj":"PR_EXT:000005308"},{"id":"T3751","span":{"begin":424,"end":429},"obj":"CHEMINF_GO_EXT:chemical_binding_or_bond_formation"},{"id":"T3752","span":{"begin":442,"end":458},"obj":"SO_EXT:0000409"},{"id":"T3753","span":{"begin":462,"end":467},"obj":"PR_EXT:000005311"},{"id":"T3754","span":{"begin":484,"end":500},"obj":"SO_EXT:0000409"},{"id":"T3755","span":{"begin":520,"end":531},"obj":"CHEBI_GO_EXT:antioxidant"},{"id":"T3756","span":{"begin":524,"end":531},"obj":"CHEBI_MOP_EXT:oxidising_agent_or_oxidation"},{"id":"T3757","span":{"begin":535,"end":538},"obj":"CHEBI_SO_EXT:DNA"},{"id":"T3758","span":{"begin":535,"end":545},"obj":"GO:0006281"},{"id":"T3759","span":{"begin":546,"end":551},"obj":"SO_EXT:0000704"},{"id":"T3760","span":{"begin":629,"end":634},"obj":"PR_EXT:000005311"},{"id":"T3761","span":{"begin":640,"end":651},"obj":"CHEBI_GO_EXT:antioxidant"},{"id":"T3762","span":{"begin":644,"end":651},"obj":"CHEBI_MOP_EXT:oxidising_agent_or_oxidation"},{"id":"T3763","span":{"begin":656,"end":659},"obj":"CHEBI_SO_EXT:DNA"},{"id":"T3764","span":{"begin":656,"end":666},"obj":"GO:0006281"},{"id":"T3765","span":{"begin":667,"end":672},"obj":"SO_EXT:0000704"},{"id":"T3766","span":{"begin":683,"end":694},"obj":"NCBITaxon:1"},{"id":"T3767","span":{"begin":720,"end":725},"obj":"PR_EXT:000005311"},{"id":"T3768","span":{"begin":753,"end":764},"obj":"CHEBI_GO_EXT:antioxidant"},{"id":"T3769","span":{"begin":757,"end":764},"obj":"CHEBI_MOP_EXT:oxidising_agent_or_oxidation"},{"id":"T3770","span":{"begin":768,"end":771},"obj":"CHEBI_SO_EXT:DNA"},{"id":"T3771","span":{"begin":768,"end":778},"obj":"GO:0006281"},{"id":"T3772","span":{"begin":779,"end":784},"obj":"SO_EXT:0000704"},{"id":"T3773","span":{"begin":788,"end":797},"obj":"GO:0065007"},{"id":"T3774","span":{"begin":803,"end":816},"obj":"GO_EXT:transcription"},{"id":"T3775","span":{"begin":803,"end":823},"obj":"GO_EXT:transcription_factor"},{"id":"T3776","span":{"begin":866,"end":882},"obj":"SO_EXT:0000409"}],"text":"These results support the hypothesis that each of the antioxidant or DNA repair genes correlated with CEBPG in non-BC individuals is regulated by CEBPG. This is supported by the specificity of the CEBPG correlation. That is, there was lack of correlation between any of the other five transcription factors assessed and these target genes. Of particular note is the lack of correlation of the target genes with CEBPB, which binds to the same recognition site as CEBPG, and shares its recognition site within each of the antioxidant or DNA repair genes. However, there are alternative explanations for the observed correlation of CEBPG with antioxidant and DNA repair genes in non-BC individuals. One possibility is that CEBPG and each of the correlated antioxidant or DNA repair genes is regulated by a transcription factor that is as yet undiscovered, and/or has a recognition site that is not yet known and was not in the Genomatix software database."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T4016","span":{"begin":69,"end":79},"obj":"GO:0006281"},{"id":"T4017","span":{"begin":80,"end":85},"obj":"SO:0000704"},{"id":"T4018","span":{"begin":102,"end":107},"obj":"PR:000005311"},{"id":"T4019","span":{"begin":118,"end":129},"obj":"NCBITaxon:1"},{"id":"T4020","span":{"begin":133,"end":142},"obj":"GO:0065007"},{"id":"T4021","span":{"begin":146,"end":151},"obj":"PR:000005311"},{"id":"T4022","span":{"begin":197,"end":202},"obj":"PR:000005311"},{"id":"T4023","span":{"begin":333,"end":338},"obj":"SO:0000704"},{"id":"T4024","span":{"begin":400,"end":405},"obj":"SO:0000704"},{"id":"T4025","span":{"begin":411,"end":416},"obj":"PR:000005308"},{"id":"T4026","span":{"begin":442,"end":458},"obj":"SO:0000409"},{"id":"T4027","span":{"begin":462,"end":467},"obj":"PR:000005311"},{"id":"T4028","span":{"begin":484,"end":500},"obj":"SO:0000409"},{"id":"T4029","span":{"begin":535,"end":545},"obj":"GO:0006281"},{"id":"T4030","span":{"begin":546,"end":551},"obj":"SO:0000704"},{"id":"T4031","span":{"begin":629,"end":634},"obj":"PR:000005311"},{"id":"T4032","span":{"begin":656,"end":666},"obj":"GO:0006281"},{"id":"T4033","span":{"begin":667,"end":672},"obj":"SO:0000704"},{"id":"T4034","span":{"begin":683,"end":694},"obj":"NCBITaxon:1"},{"id":"T4035","span":{"begin":720,"end":725},"obj":"PR:000005311"},{"id":"T4036","span":{"begin":768,"end":778},"obj":"GO:0006281"},{"id":"T4037","span":{"begin":779,"end":784},"obj":"SO:0000704"},{"id":"T4038","span":{"begin":788,"end":797},"obj":"GO:0065007"},{"id":"T4039","span":{"begin":866,"end":882},"obj":"SO:0000409"}],"text":"These results support the hypothesis that each of the antioxidant or DNA repair genes correlated with CEBPG in non-BC individuals is regulated by CEBPG. This is supported by the specificity of the CEBPG correlation. That is, there was lack of correlation between any of the other five transcription factors assessed and these target genes. Of particular note is the lack of correlation of the target genes with CEBPB, which binds to the same recognition site as CEBPG, and shares its recognition site within each of the antioxidant or DNA repair genes. However, there are alternative explanations for the observed correlation of CEBPG with antioxidant and DNA repair genes in non-BC individuals. One possibility is that CEBPG and each of the correlated antioxidant or DNA repair genes is regulated by a transcription factor that is as yet undiscovered, and/or has a recognition site that is not yet known and was not in the Genomatix software database."}