PMC:1283364 / 48463-48661 JSONTXT

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{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T10210","span":{"begin":36,"end":39},"obj":"CHEBI:50845"},{"id":"T10211","span":{"begin":98,"end":108},"obj":"CHEBI_SO_EXT:C_terminus_or_C_terminal_region"},{"id":"T10212","span":{"begin":140,"end":146},"obj":"SO_EXT:sequence_altered_entity_or_alteration_process"},{"id":"T10213","span":{"begin":147,"end":155},"obj":"CHEBI_PR_EXT:protein"}],"text":" We demonstrate that treatment with dox suppresses steady-state levels of both APPswe/ind and its C-terminal fragments, indicating that the mutant proteins have a relatively short half-life in vivo."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T9948","span":{"begin":36,"end":39},"obj":"CHEBI:50845"}],"text":" We demonstrate that treatment with dox suppresses steady-state levels of both APPswe/ind and its C-terminal fragments, indicating that the mutant proteins have a relatively short half-life in vivo."}