Id |
Subject |
Object |
Predicate |
Lexical cue |
T9487 |
0-8 |
JJ |
denotes |
Putative |
T9488 |
18-23 |
NN |
denotes |
Basis |
T9489 |
9-17 |
JJ |
denotes |
Cellular |
T9490 |
24-26 |
IN |
denotes |
of |
T9491 |
27-35 |
VBN |
denotes |
Enhanced |
T9492 |
41-55 |
NN |
denotes |
Discrimination |
T9493 |
36-40 |
NN |
denotes |
Odor |
T9494 |
56-59 |
CC |
denotes |
and |
T9495 |
60-68 |
NN |
denotes |
Learning |
T9496 |
68-285 |
sentence |
denotes |
AMPAR properties were altered specifically in neurons of forebrain areas, most notably olfactory bulb, olfactory cortex, and other cortical areas and hippocampus, leading to enhanced odor discrimination and learning. |
T9497 |
69-74 |
NN |
denotes |
AMPAR |
T9498 |
75-85 |
NNS |
denotes |
properties |
T9499 |
91-98 |
VBN |
denotes |
altered |
T9500 |
86-90 |
VBD |
denotes |
were |
T9501 |
99-111 |
RB |
denotes |
specifically |
T9502 |
112-114 |
IN |
denotes |
in |
T9503 |
115-122 |
NNS |
denotes |
neurons |
T9504 |
123-125 |
IN |
denotes |
of |
T9505 |
126-135 |
NN |
denotes |
forebrain |
T9506 |
136-141 |
NNS |
denotes |
areas |
T9507 |
141-143 |
, |
denotes |
, |
T9508 |
143-147 |
RBS |
denotes |
most |
T9509 |
148-155 |
RB |
denotes |
notably |
T9510 |
166-170 |
NN |
denotes |
bulb |
T9511 |
156-165 |
JJ |
denotes |
olfactory |
T9512 |
170-172 |
, |
denotes |
, |
T9513 |
172-181 |
JJ |
denotes |
olfactory |
T9514 |
182-188 |
NN |
denotes |
cortex |
T9515 |
188-190 |
, |
denotes |
, |
T9516 |
190-193 |
CC |
denotes |
and |
T9517 |
194-199 |
JJ |
denotes |
other |
T9518 |
209-214 |
NNS |
denotes |
areas |
T9519 |
200-208 |
JJ |
denotes |
cortical |
T9520 |
215-218 |
CC |
denotes |
and |
T9521 |
219-230 |
NN |
denotes |
hippocampus |
T9522 |
230-232 |
, |
denotes |
, |
T9523 |
232-239 |
VBG |
denotes |
leading |
T9524 |
240-242 |
IN |
denotes |
to |
T9525 |
243-251 |
VBN |
denotes |
enhanced |
T9526 |
257-271 |
NN |
denotes |
discrimination |
T9527 |
252-256 |
NN |
denotes |
odor |
T9528 |
272-275 |
CC |
denotes |
and |
T9529 |
276-284 |
NN |
denotes |
learning |
T9530 |
284-285 |
. |
denotes |
. |
T9531 |
285-539 |
sentence |
denotes |
Interestingly, transgenic expression of GFPGluR-B in GluR-BΔFB mice (genetic “rescue”), specifically in piriform cortex and hippocampus with no detectable expression in the olfactory bulb, did not alter enhanced discrimination and learning capabilities. |
T9532 |
286-299 |
RB |
denotes |
Interestingly |
T9533 |
483-488 |
VB |
denotes |
alter |
T9534 |
299-301 |
, |
denotes |
, |
T9535 |
301-311 |
JJ |
denotes |
transgenic |
T9536 |
312-322 |
NN |
denotes |
expression |
T9537 |
323-325 |
IN |
denotes |
of |
T9538 |
326-333 |
NN |
denotes |
GFPGluR |
T9539 |
334-335 |
NN |
denotes |
B |
T9540 |
333-334 |
HYPH |
denotes |
- |
T9541 |
336-338 |
IN |
denotes |
in |
T9542 |
339-343 |
NN |
denotes |
GluR |
T9543 |
344-348 |
NN |
denotes |
BΔFB |
T9544 |
343-344 |
HYPH |
denotes |
- |
T9545 |
349-353 |
NNS |
denotes |
mice |
T9546 |
354-355 |
-LRB- |
denotes |
( |
T9547 |
364-370 |
NN |
denotes |
rescue |
T9548 |
355-362 |
JJ |
denotes |
genetic |
T9549 |
363-364 |
`` |
denotes |
“ |
T9550 |
370-371 |
'' |
denotes |
” |
T9551 |
371-372 |
-RRB- |
denotes |
) |
T9552 |
372-374 |
, |
denotes |
, |
T9553 |
374-386 |
RB |
denotes |
specifically |
T9554 |
387-389 |
IN |
denotes |
in |
T9555 |
390-398 |
JJ |
denotes |
piriform |
T9556 |
399-405 |
NN |
denotes |
cortex |
T9557 |
406-409 |
CC |
denotes |
and |
T9558 |
410-421 |
NN |
denotes |
hippocampus |
T9559 |
422-426 |
IN |
denotes |
with |
T9560 |
427-429 |
DT |
denotes |
no |
T9561 |
441-451 |
NN |
denotes |
expression |
T9562 |
430-440 |
JJ |
denotes |
detectable |
T9563 |
452-454 |
IN |
denotes |
in |
T9564 |
455-458 |
DT |
denotes |
the |
T9565 |
469-473 |
NN |
denotes |
bulb |
T9566 |
459-468 |
JJ |
denotes |
olfactory |
T9567 |
473-475 |
, |
denotes |
, |
T9568 |
475-478 |
VBD |
denotes |
did |
T9569 |
479-482 |
RB |
denotes |
not |
T9570 |
489-497 |
VBN |
denotes |
enhanced |
T9571 |
526-538 |
NNS |
denotes |
capabilities |
T9572 |
498-512 |
NN |
denotes |
discrimination |
T9573 |
513-516 |
CC |
denotes |
and |
T9574 |
517-525 |
NN |
denotes |
learning |
T9575 |
538-539 |
. |
denotes |
. |
T9576 |
539-642 |
sentence |
denotes |
This is consistent with a primary role of the olfactory bulb in olfactory discrimination and learning. |
T9577 |
540-544 |
DT |
denotes |
This |
T9578 |
545-547 |
VBZ |
denotes |
is |
T9579 |
548-558 |
JJ |
denotes |
consistent |
T9580 |
559-563 |
IN |
denotes |
with |
T9581 |
564-565 |
DT |
denotes |
a |
T9582 |
574-578 |
NN |
denotes |
role |
T9583 |
566-573 |
JJ |
denotes |
primary |
T9584 |
579-581 |
IN |
denotes |
of |
T9585 |
582-585 |
DT |
denotes |
the |
T9586 |
596-600 |
NN |
denotes |
bulb |
T9587 |
586-595 |
JJ |
denotes |
olfactory |
T9588 |
601-603 |
IN |
denotes |
in |
T9589 |
604-613 |
JJ |
denotes |
olfactory |
T9590 |
614-628 |
NN |
denotes |
discrimination |
T9591 |
629-632 |
CC |
denotes |
and |
T9592 |
633-641 |
NN |
denotes |
learning |
T9593 |
641-642 |
. |
denotes |
. |
T9594 |
642-796 |
sentence |
denotes |
Alternatively, transgenic protein levels might have been too low to alter discrimination and learning capabilities, although memory was clearly affected. |
T9595 |
643-656 |
RB |
denotes |
Alternatively |
T9596 |
695-699 |
VBN |
denotes |
been |
T9597 |
656-658 |
, |
denotes |
, |
T9598 |
658-668 |
JJ |
denotes |
transgenic |
T9599 |
677-683 |
NNS |
denotes |
levels |
T9600 |
669-676 |
NN |
denotes |
protein |
T9601 |
684-689 |
MD |
denotes |
might |
T9602 |
690-694 |
VB |
denotes |
have |
T9603 |
700-703 |
RB |
denotes |
too |
T9604 |
704-707 |
JJ |
denotes |
low |
T9605 |
708-710 |
TO |
denotes |
to |
T9606 |
711-716 |
VB |
denotes |
alter |
T9607 |
717-731 |
NN |
denotes |
discrimination |
T9608 |
745-757 |
NNS |
denotes |
capabilities |
T9609 |
732-735 |
CC |
denotes |
and |
T9610 |
736-744 |
NN |
denotes |
learning |
T9611 |
757-759 |
, |
denotes |
, |
T9612 |
759-767 |
IN |
denotes |
although |
T9613 |
787-795 |
VBN |
denotes |
affected |
T9614 |
768-774 |
NN |
denotes |
memory |
T9615 |
775-778 |
VBD |
denotes |
was |
T9616 |
779-786 |
RB |
denotes |
clearly |
T9617 |
795-796 |
. |
denotes |
. |
T9618 |
796-886 |
sentence |
denotes |
This notion will be further tested in mice with piriform cortex-specific GluR-B ablation. |
T9619 |
797-801 |
DT |
denotes |
This |
T9620 |
802-808 |
NN |
denotes |
notion |
T9621 |
825-831 |
VBN |
denotes |
tested |
T9622 |
809-813 |
MD |
denotes |
will |
T9623 |
814-816 |
VB |
denotes |
be |
T9624 |
817-824 |
RB |
denotes |
further |
T9625 |
832-834 |
IN |
denotes |
in |
T9626 |
835-839 |
NNS |
denotes |
mice |
T9627 |
840-844 |
IN |
denotes |
with |
T9628 |
845-853 |
JJ |
denotes |
piriform |
T9629 |
854-860 |
NN |
denotes |
cortex |
T9630 |
861-869 |
JJ |
denotes |
specific |
T9631 |
860-861 |
HYPH |
denotes |
- |
T9632 |
877-885 |
NN |
denotes |
ablation |
T9633 |
870-874 |
NN |
denotes |
GluR |
T9634 |
875-876 |
NN |
denotes |
B |
T9635 |
874-875 |
HYPH |
denotes |
- |
T9636 |
885-886 |
. |
denotes |
. |
T9637 |
886-1155 |
sentence |
denotes |
A direct contribution to the phenotype by Ca2+ influx through genetically modified AMPA channels seems to be likely, since mice expressing Q/R site-unedited GluR-B showed even better odor learning and discrimination performance compared with mice with depleted GluR-B. |
T9638 |
887-888 |
DT |
denotes |
A |
T9639 |
896-908 |
NN |
denotes |
contribution |
T9640 |
889-895 |
JJ |
denotes |
direct |
T9641 |
984-989 |
VBZ |
denotes |
seems |
T9642 |
909-911 |
IN |
denotes |
to |
T9643 |
912-915 |
DT |
denotes |
the |
T9644 |
916-925 |
NN |
denotes |
phenotype |
T9645 |
926-928 |
IN |
denotes |
by |
T9646 |
929-932 |
NN |
denotes |
Ca2 |
T9647 |
934-940 |
NN |
denotes |
influx |
T9648 |
932-933 |
SYM |
denotes |
+ |
T9649 |
941-948 |
IN |
denotes |
through |
T9650 |
949-960 |
RB |
denotes |
genetically |
T9651 |
961-969 |
VBN |
denotes |
modified |
T9652 |
975-983 |
NNS |
denotes |
channels |
T9653 |
970-974 |
NN |
denotes |
AMPA |
T9654 |
990-992 |
TO |
denotes |
to |
T9655 |
993-995 |
VB |
denotes |
be |
T9656 |
996-1002 |
JJ |
denotes |
likely |
T9657 |
1002-1004 |
, |
denotes |
, |
T9658 |
1004-1009 |
IN |
denotes |
since |
T9659 |
1051-1057 |
VBD |
denotes |
showed |
T9660 |
1010-1014 |
NNS |
denotes |
mice |
T9661 |
1015-1025 |
VBG |
denotes |
expressing |
T9662 |
1026-1027 |
NN |
denotes |
Q |
T9663 |
1028-1029 |
NN |
denotes |
R |
T9664 |
1027-1028 |
HYPH |
denotes |
/ |
T9665 |
1049-1050 |
NN |
denotes |
B |
T9666 |
1030-1034 |
NN |
denotes |
site |
T9667 |
1035-1043 |
JJ |
denotes |
unedited |
T9668 |
1034-1035 |
HYPH |
denotes |
- |
T9669 |
1044-1048 |
NN |
denotes |
GluR |
T9670 |
1048-1049 |
HYPH |
denotes |
- |
T9671 |
1058-1062 |
RB |
denotes |
even |
T9672 |
1063-1069 |
JJR |
denotes |
better |
T9673 |
1103-1114 |
NN |
denotes |
performance |
T9674 |
1070-1074 |
NN |
denotes |
odor |
T9675 |
1075-1083 |
NN |
denotes |
learning |
T9676 |
1084-1087 |
CC |
denotes |
and |
T9677 |
1088-1102 |
NN |
denotes |
discrimination |
T9678 |
1115-1123 |
VBN |
denotes |
compared |
T9679 |
1124-1128 |
IN |
denotes |
with |
T9680 |
1129-1133 |
NNS |
denotes |
mice |
T9681 |
1134-1138 |
IN |
denotes |
with |
T9682 |
1139-1147 |
VBN |
denotes |
depleted |
T9683 |
1153-1154 |
NN |
denotes |
B |
T9684 |
1148-1152 |
NN |
denotes |
GluR |
T9685 |
1152-1153 |
HYPH |
denotes |
- |
T9686 |
1154-1155 |
. |
denotes |
. |
T9687 |
1155-1288 |
sentence |
denotes |
In both mouse models Ca2+ influx through AMPA channels is increased, whereas the effect on the macroscopic AMPA conductance differs. |
T9688 |
1156-1158 |
IN |
denotes |
In |
T9689 |
1214-1223 |
VBN |
denotes |
increased |
T9690 |
1159-1163 |
DT |
denotes |
both |
T9691 |
1170-1176 |
NNS |
denotes |
models |
T9692 |
1164-1169 |
NN |
denotes |
mouse |
T9693 |
1177-1180 |
NN |
denotes |
Ca2 |
T9694 |
1182-1188 |
NN |
denotes |
influx |
T9695 |
1180-1181 |
SYM |
denotes |
+ |
T9696 |
1189-1196 |
IN |
denotes |
through |
T9697 |
1197-1201 |
NN |
denotes |
AMPA |
T9698 |
1202-1210 |
NNS |
denotes |
channels |
T9699 |
1211-1213 |
VBZ |
denotes |
is |
T9700 |
1223-1225 |
, |
denotes |
, |
T9701 |
1225-1232 |
IN |
denotes |
whereas |
T9702 |
1280-1287 |
VBZ |
denotes |
differs |
T9703 |
1233-1236 |
DT |
denotes |
the |
T9704 |
1237-1243 |
NN |
denotes |
effect |
T9705 |
1244-1246 |
IN |
denotes |
on |
T9706 |
1247-1250 |
DT |
denotes |
the |
T9707 |
1268-1279 |
NN |
denotes |
conductance |
T9708 |
1251-1262 |
JJ |
denotes |
macroscopic |
T9709 |
1263-1267 |
NN |
denotes |
AMPA |
T9710 |
1287-1288 |
. |
denotes |
. |
T9711 |
1288-1442 |
sentence |
denotes |
AMPAR currents are reduced in mice not expressing GluR-B [51], possibly due to fewer synaptic AMPA channels and impaired AMPAR trafficking and recycling. |
T9712 |
1289-1294 |
NN |
denotes |
AMPAR |
T9713 |
1295-1303 |
NNS |
denotes |
currents |
T9714 |
1308-1315 |
VBN |
denotes |
reduced |
T9715 |
1304-1307 |
VBP |
denotes |
are |
T9716 |
1316-1318 |
IN |
denotes |
in |
T9717 |
1319-1323 |
NNS |
denotes |
mice |
T9718 |
1324-1327 |
RB |
denotes |
not |
T9719 |
1328-1338 |
VBG |
denotes |
expressing |
T9720 |
1339-1343 |
NN |
denotes |
GluR |
T9721 |
1344-1345 |
NN |
denotes |
B |
T9722 |
1343-1344 |
HYPH |
denotes |
- |
T9723 |
1346-1347 |
-LRB- |
denotes |
[ |
T9724 |
1347-1349 |
CD |
denotes |
51 |
T9725 |
1349-1350 |
-RRB- |
denotes |
] |
T9726 |
1350-1352 |
, |
denotes |
, |
T9727 |
1352-1360 |
RB |
denotes |
possibly |
T9728 |
1361-1364 |
IN |
denotes |
due |
T9729 |
1365-1367 |
IN |
denotes |
to |
T9730 |
1368-1373 |
JJR |
denotes |
fewer |
T9731 |
1388-1396 |
NNS |
denotes |
channels |
T9732 |
1374-1382 |
JJ |
denotes |
synaptic |
T9733 |
1383-1387 |
NN |
denotes |
AMPA |
T9734 |
1397-1400 |
CC |
denotes |
and |
T9735 |
1401-1409 |
VBN |
denotes |
impaired |
T9736 |
1416-1427 |
NN |
denotes |
trafficking |
T9737 |
1410-1415 |
NN |
denotes |
AMPAR |
T9738 |
1428-1431 |
CC |
denotes |
and |
T9739 |
1432-1441 |
NN |
denotes |
recycling |
T9740 |
1441-1442 |
. |
denotes |
. |
T9741 |
1442-1843 |
sentence |
denotes |
In mice expressing the unedited form of GluR-B(Q), macroscopic conductance in whole-cell patches of CA1 pyramidals is increased [60], but excitatory transmission in CA3-to-CA1 cell synapses is somewhat reduced, in spite of a lower threshold for generating a population spike [58], indicating increased synaptic excitability by sustained GluR-B(Q) expression, in line with the seizure-prone phenotype. |
T9742 |
1443-1445 |
IN |
denotes |
In |
T9743 |
1561-1570 |
VBN |
denotes |
increased |
T9744 |
1446-1450 |
NNS |
denotes |
mice |
T9745 |
1451-1461 |
VBG |
denotes |
expressing |
T9746 |
1462-1465 |
DT |
denotes |
the |
T9747 |
1475-1479 |
NN |
denotes |
form |
T9748 |
1466-1474 |
JJ |
denotes |
unedited |
T9749 |
1480-1482 |
IN |
denotes |
of |
T9750 |
1483-1487 |
NN |
denotes |
GluR |
T9751 |
1490-1491 |
NN |
denotes |
Q |
T9752 |
1487-1488 |
HYPH |
denotes |
- |
T9753 |
1488-1489 |
NN |
denotes |
B |
T9754 |
1489-1490 |
-LRB- |
denotes |
( |
T9755 |
1491-1492 |
-RRB- |
denotes |
) |
T9756 |
1492-1494 |
, |
denotes |
, |
T9757 |
1494-1505 |
JJ |
denotes |
macroscopic |
T9758 |
1506-1517 |
NN |
denotes |
conductance |
T9759 |
1518-1520 |
IN |
denotes |
in |
T9760 |
1521-1526 |
JJ |
denotes |
whole |
T9761 |
1527-1531 |
NN |
denotes |
cell |
T9762 |
1526-1527 |
HYPH |
denotes |
- |
T9763 |
1532-1539 |
NNS |
denotes |
patches |
T9764 |
1540-1542 |
IN |
denotes |
of |
T9765 |
1543-1546 |
NN |
denotes |
CA1 |
T9766 |
1547-1557 |
NNS |
denotes |
pyramidals |
T9767 |
1558-1560 |
VBZ |
denotes |
is |
T9768 |
1571-1572 |
-LRB- |
denotes |
[ |
T9769 |
1572-1574 |
CD |
denotes |
60 |
T9770 |
1574-1575 |
-RRB- |
denotes |
] |
T9771 |
1575-1577 |
, |
denotes |
, |
T9772 |
1577-1580 |
CC |
denotes |
but |
T9773 |
1581-1591 |
JJ |
denotes |
excitatory |
T9774 |
1592-1604 |
NN |
denotes |
transmission |
T9775 |
1633-1635 |
VBZ |
denotes |
is |
T9776 |
1605-1607 |
IN |
denotes |
in |
T9777 |
1608-1611 |
NN |
denotes |
CA3 |
T9778 |
1624-1632 |
NNS |
denotes |
synapses |
T9779 |
1611-1612 |
HYPH |
denotes |
- |
T9780 |
1612-1614 |
IN |
denotes |
to |
T9781 |
1614-1615 |
HYPH |
denotes |
- |
T9782 |
1615-1618 |
NN |
denotes |
CA1 |
T9783 |
1619-1623 |
NN |
denotes |
cell |
T9784 |
1636-1644 |
RB |
denotes |
somewhat |
T9785 |
1645-1652 |
JJ |
denotes |
reduced |
T9786 |
1652-1654 |
, |
denotes |
, |
T9787 |
1654-1656 |
IN |
denotes |
in |
T9788 |
1657-1662 |
NN |
denotes |
spite |
T9789 |
1663-1665 |
IN |
denotes |
of |
T9790 |
1666-1667 |
DT |
denotes |
a |
T9791 |
1674-1683 |
NN |
denotes |
threshold |
T9792 |
1668-1673 |
JJR |
denotes |
lower |
T9793 |
1684-1687 |
IN |
denotes |
for |
T9794 |
1688-1698 |
VBG |
denotes |
generating |
T9795 |
1699-1700 |
DT |
denotes |
a |
T9796 |
1712-1717 |
NN |
denotes |
spike |
T9797 |
1701-1711 |
NN |
denotes |
population |
T9798 |
1718-1719 |
-LRB- |
denotes |
[ |
T9799 |
1719-1721 |
CD |
denotes |
58 |
T9800 |
1721-1722 |
-RRB- |
denotes |
] |
T9801 |
1722-1724 |
, |
denotes |
, |
T9802 |
1724-1734 |
VBG |
denotes |
indicating |
T9803 |
1735-1744 |
VBN |
denotes |
increased |
T9804 |
1754-1766 |
NN |
denotes |
excitability |
T9805 |
1745-1753 |
JJ |
denotes |
synaptic |
T9806 |
1767-1769 |
IN |
denotes |
by |
T9807 |
1770-1779 |
VBN |
denotes |
sustained |
T9808 |
1790-1800 |
NN |
denotes |
expression |
T9809 |
1780-1784 |
NN |
denotes |
GluR |
T9810 |
1787-1788 |
NN |
denotes |
Q |
T9811 |
1784-1785 |
HYPH |
denotes |
- |
T9812 |
1785-1786 |
NN |
denotes |
B |
T9813 |
1786-1787 |
-LRB- |
denotes |
( |
T9814 |
1788-1789 |
-RRB- |
denotes |
) |
T9815 |
1800-1802 |
, |
denotes |
, |
T9816 |
1802-1804 |
IN |
denotes |
in |
T9817 |
1805-1809 |
NN |
denotes |
line |
T9818 |
1810-1814 |
IN |
denotes |
with |
T9819 |
1815-1818 |
DT |
denotes |
the |
T9820 |
1833-1842 |
NN |
denotes |
phenotype |
T9821 |
1819-1826 |
NN |
denotes |
seizure |
T9822 |
1827-1832 |
JJ |
denotes |
prone |
T9823 |
1826-1827 |
HYPH |
denotes |
- |
T9824 |
1842-1843 |
. |
denotes |
. |
T9825 |
1843-1921 |
sentence |
denotes |
Yet, both mouse models yield enhanced discrimination and learning capability. |
T9826 |
1844-1847 |
RB |
denotes |
Yet |
T9827 |
1867-1872 |
VBP |
denotes |
yield |
T9828 |
1847-1849 |
, |
denotes |
, |
T9829 |
1849-1853 |
DT |
denotes |
both |
T9830 |
1860-1866 |
NNS |
denotes |
models |
T9831 |
1854-1859 |
NN |
denotes |
mouse |
T9832 |
1873-1881 |
VBN |
denotes |
enhanced |
T9833 |
1910-1920 |
NN |
denotes |
capability |
T9834 |
1882-1896 |
NN |
denotes |
discrimination |
T9835 |
1897-1900 |
CC |
denotes |
and |
T9836 |
1901-1909 |
NN |
denotes |
learning |
T9837 |
1920-1921 |
. |
denotes |
. |
T9838 |
1921-2089 |
sentence |
denotes |
The milder phenotype upon GluR-B depletion could be attributed to reduced AMPAR densities at synapses [40,41] and therefore probably to a lesser extent of Ca2+ influx. |
T9839 |
1922-1925 |
DT |
denotes |
The |
T9840 |
1933-1942 |
NN |
denotes |
phenotype |
T9841 |
1926-1932 |
JJR |
denotes |
milder |
T9842 |
1974-1984 |
VBN |
denotes |
attributed |
T9843 |
1943-1947 |
IN |
denotes |
upon |
T9844 |
1948-1952 |
NN |
denotes |
GluR |
T9845 |
1953-1954 |
NN |
denotes |
B |
T9846 |
1952-1953 |
HYPH |
denotes |
- |
T9847 |
1955-1964 |
NN |
denotes |
depletion |
T9848 |
1965-1970 |
MD |
denotes |
could |
T9849 |
1971-1973 |
VB |
denotes |
be |
T9850 |
1985-1987 |
IN |
denotes |
to |
T9851 |
1988-1995 |
VBN |
denotes |
reduced |
T9852 |
2002-2011 |
NNS |
denotes |
densities |
T9853 |
1996-2001 |
NN |
denotes |
AMPAR |
T9854 |
2012-2014 |
IN |
denotes |
at |
T9855 |
2015-2023 |
NNS |
denotes |
synapses |
T9856 |
2024-2025 |
-LRB- |
denotes |
[ |
T9857 |
2028-2030 |
CD |
denotes |
41 |
T9858 |
2025-2027 |
CD |
denotes |
40 |
T9859 |
2027-2028 |
, |
denotes |
, |
T9860 |
2030-2031 |
-RRB- |
denotes |
] |
T9861 |
2032-2035 |
CC |
denotes |
and |
T9862 |
2036-2045 |
RB |
denotes |
therefore |
T9863 |
2055-2057 |
IN |
denotes |
to |
T9864 |
2046-2054 |
RB |
denotes |
probably |
T9865 |
2058-2059 |
DT |
denotes |
a |
T9866 |
2067-2073 |
NN |
denotes |
extent |
T9867 |
2060-2066 |
JJR |
denotes |
lesser |
T9868 |
2074-2076 |
IN |
denotes |
of |
T9869 |
2077-2080 |
NN |
denotes |
Ca2 |
T9870 |
2082-2088 |
NN |
denotes |
influx |
T9871 |
2080-2081 |
SYM |
denotes |
+ |
T9872 |
2088-2089 |
. |
denotes |
. |
T9873 |
2089-2364 |
sentence |
denotes |
This is further supported by kainate-induced Co2+ uptake in acute brain slices, revealing considerably higher Co2+ uptake via Ca2+-permeable AMPARs in hippocampal pyramidal neurons of mice expressing GluR-B(Q), than those lacking GluR-B (DRS, RS, and PHS, unpublished data). |
T9874 |
2090-2094 |
DT |
denotes |
This |
T9875 |
2106-2115 |
VBN |
denotes |
supported |
T9876 |
2095-2097 |
VBZ |
denotes |
is |
T9877 |
2098-2105 |
RB |
denotes |
further |
T9878 |
2116-2118 |
IN |
denotes |
by |
T9879 |
2119-2126 |
NN |
denotes |
kainate |
T9880 |
2127-2134 |
VBN |
denotes |
induced |
T9881 |
2126-2127 |
HYPH |
denotes |
- |
T9882 |
2140-2146 |
NN |
denotes |
uptake |
T9883 |
2135-2138 |
NN |
denotes |
Co2 |
T9884 |
2138-2139 |
SYM |
denotes |
+ |
T9885 |
2147-2149 |
IN |
denotes |
in |
T9886 |
2150-2155 |
JJ |
denotes |
acute |
T9887 |
2162-2168 |
NNS |
denotes |
slices |
T9888 |
2156-2161 |
NN |
denotes |
brain |
T9889 |
2168-2170 |
, |
denotes |
, |
T9890 |
2170-2179 |
VBG |
denotes |
revealing |
T9891 |
2180-2192 |
RB |
denotes |
considerably |
T9892 |
2193-2199 |
JJR |
denotes |
higher |
T9893 |
2205-2211 |
NN |
denotes |
uptake |
T9894 |
2200-2203 |
NN |
denotes |
Co2 |
T9895 |
2203-2204 |
SYM |
denotes |
+ |
T9896 |
2212-2215 |
IN |
denotes |
via |
T9897 |
2216-2219 |
NN |
denotes |
Ca2 |
T9898 |
2221-2230 |
JJ |
denotes |
permeable |
T9899 |
2219-2220 |
SYM |
denotes |
+ |
T9900 |
2220-2221 |
HYPH |
denotes |
- |
T9901 |
2231-2237 |
NNS |
denotes |
AMPARs |
T9902 |
2238-2240 |
IN |
denotes |
in |
T9903 |
2241-2252 |
JJ |
denotes |
hippocampal |
T9904 |
2263-2270 |
NNS |
denotes |
neurons |
T9905 |
2253-2262 |
JJ |
denotes |
pyramidal |
T9906 |
2271-2273 |
IN |
denotes |
of |
T9907 |
2274-2278 |
NNS |
denotes |
mice |
T9908 |
2279-2289 |
VBG |
denotes |
expressing |
T9909 |
2290-2294 |
NN |
denotes |
GluR |
T9910 |
2295-2296 |
NN |
denotes |
B |
T9911 |
2294-2295 |
HYPH |
denotes |
- |
T9912 |
2296-2297 |
-LRB- |
denotes |
( |
T9913 |
2297-2298 |
NN |
denotes |
Q |
T9914 |
2298-2299 |
-RRB- |
denotes |
) |
T9915 |
2299-2301 |
, |
denotes |
, |
T9916 |
2301-2305 |
IN |
denotes |
than |
T9917 |
2306-2311 |
DT |
denotes |
those |
T9918 |
2312-2319 |
VBG |
denotes |
lacking |
T9919 |
2320-2324 |
NN |
denotes |
GluR |
T9920 |
2325-2326 |
NN |
denotes |
B |
T9921 |
2324-2325 |
HYPH |
denotes |
- |
T9922 |
2327-2328 |
-LRB- |
denotes |
( |
T9923 |
2358-2362 |
NNS |
denotes |
data |
T9924 |
2328-2331 |
NN |
denotes |
DRS |
T9925 |
2331-2333 |
, |
denotes |
, |
T9926 |
2333-2335 |
NN |
denotes |
RS |
T9927 |
2335-2337 |
, |
denotes |
, |
T9928 |
2337-2340 |
CC |
denotes |
and |
T9929 |
2341-2344 |
NN |
denotes |
PHS |
T9930 |
2344-2346 |
, |
denotes |
, |
T9931 |
2346-2357 |
JJ |
denotes |
unpublished |
T9932 |
2362-2363 |
-RRB- |
denotes |
) |
T9933 |
2363-2364 |
. |
denotes |
. |
T9934 |
2364-2520 |
sentence |
denotes |
Normally, GluR-B-containing AMPARs are prominently localized at the dendrodendritic synapse between mitral and granule cells in the olfactory bulb [64,65]. |
T9935 |
2365-2373 |
RB |
denotes |
Normally |
T9936 |
2416-2425 |
VBN |
denotes |
localized |
T9937 |
2373-2375 |
, |
denotes |
, |
T9938 |
2375-2379 |
NN |
denotes |
GluR |
T9939 |
2380-2381 |
NN |
denotes |
B |
T9940 |
2379-2380 |
HYPH |
denotes |
- |
T9941 |
2382-2392 |
VBG |
denotes |
containing |
T9942 |
2381-2382 |
HYPH |
denotes |
- |
T9943 |
2393-2399 |
NNS |
denotes |
AMPARs |
T9944 |
2400-2403 |
VBP |
denotes |
are |
T9945 |
2404-2415 |
RB |
denotes |
prominently |
T9946 |
2426-2428 |
IN |
denotes |
at |
T9947 |
2429-2432 |
DT |
denotes |
the |
T9948 |
2449-2456 |
NN |
denotes |
synapse |
T9949 |
2433-2448 |
JJ |
denotes |
dendrodendritic |
T9950 |
2457-2464 |
IN |
denotes |
between |
T9951 |
2465-2471 |
JJ |
denotes |
mitral |
T9952 |
2484-2489 |
NNS |
denotes |
cells |
T9953 |
2472-2475 |
CC |
denotes |
and |
T9954 |
2476-2483 |
NN |
denotes |
granule |
T9955 |
2490-2492 |
IN |
denotes |
in |
T9956 |
2493-2496 |
DT |
denotes |
the |
T9957 |
2507-2511 |
NN |
denotes |
bulb |
T9958 |
2497-2506 |
JJ |
denotes |
olfactory |
T9959 |
2512-2513 |
-LRB- |
denotes |
[ |
T9960 |
2516-2518 |
CD |
denotes |
65 |
T9961 |
2513-2515 |
CD |
denotes |
64 |
T9962 |
2515-2516 |
, |
denotes |
, |
T9963 |
2518-2519 |
-RRB- |
denotes |
] |
T9964 |
2519-2520 |
. |
denotes |
. |
T9965 |
2520-2814 |
sentence |
denotes |
As Ca2+ influx through glutamate receptors is thought to contribute to lateral and recurrent inhibition ([38] see also [39]), the absence of GluR-B, or the presence of GluR-B(Q) in the olfactory bulb, is likely to result in increased inhibition between the principal neurons in this structure. |
T9966 |
2521-2523 |
IN |
denotes |
As |
T9967 |
2567-2574 |
VBN |
denotes |
thought |
T9968 |
2524-2527 |
NN |
denotes |
Ca2 |
T9969 |
2529-2535 |
NN |
denotes |
influx |
T9970 |
2527-2528 |
SYM |
denotes |
+ |
T9971 |
2536-2543 |
IN |
denotes |
through |
T9972 |
2544-2553 |
NN |
denotes |
glutamate |
T9973 |
2554-2563 |
NNS |
denotes |
receptors |
T9974 |
2564-2566 |
VBZ |
denotes |
is |
T9975 |
2722-2724 |
VBZ |
denotes |
is |
T9976 |
2575-2577 |
TO |
denotes |
to |
T9977 |
2578-2588 |
VB |
denotes |
contribute |
T9978 |
2589-2591 |
IN |
denotes |
to |
T9979 |
2592-2599 |
JJ |
denotes |
lateral |
T9980 |
2614-2624 |
NN |
denotes |
inhibition |
T9981 |
2600-2603 |
CC |
denotes |
and |
T9982 |
2604-2613 |
JJ |
denotes |
recurrent |
T9983 |
2625-2626 |
-LRB- |
denotes |
( |
T9984 |
2627-2629 |
CD |
denotes |
38 |
T9985 |
2626-2627 |
-LRB- |
denotes |
[ |
T9986 |
2629-2630 |
-RRB- |
denotes |
] |
T9987 |
2631-2634 |
VBP |
denotes |
see |
T9988 |
2635-2639 |
RB |
denotes |
also |
T9989 |
2640-2641 |
-LRB- |
denotes |
[ |
T9990 |
2641-2643 |
CD |
denotes |
39 |
T9991 |
2643-2644 |
-RRB- |
denotes |
] |
T9992 |
2644-2645 |
-RRB- |
denotes |
) |
T9993 |
2645-2647 |
, |
denotes |
, |
T9994 |
2647-2650 |
DT |
denotes |
the |
T9995 |
2651-2658 |
NN |
denotes |
absence |
T9996 |
2659-2661 |
IN |
denotes |
of |
T9997 |
2662-2666 |
NN |
denotes |
GluR |
T9998 |
2667-2668 |
NN |
denotes |
B |
T9999 |
2666-2667 |
HYPH |
denotes |
- |
T10000 |
2668-2670 |
, |
denotes |
, |
T10001 |
2670-2672 |
CC |
denotes |
or |
T10002 |
2673-2676 |
DT |
denotes |
the |
T10003 |
2677-2685 |
NN |
denotes |
presence |
T10004 |
2686-2688 |
IN |
denotes |
of |
T10005 |
2689-2693 |
NN |
denotes |
GluR |
T10006 |
2694-2695 |
NN |
denotes |
B |
T10007 |
2693-2694 |
HYPH |
denotes |
- |
T10008 |
2695-2696 |
-LRB- |
denotes |
( |
T10009 |
2696-2697 |
NN |
denotes |
Q |
T10010 |
2697-2698 |
-RRB- |
denotes |
) |
T10011 |
2699-2701 |
IN |
denotes |
in |
T10012 |
2702-2705 |
DT |
denotes |
the |
T10013 |
2716-2720 |
NN |
denotes |
bulb |
T10014 |
2706-2715 |
JJ |
denotes |
olfactory |
T10015 |
2720-2722 |
, |
denotes |
, |
T10016 |
2725-2731 |
JJ |
denotes |
likely |
T10017 |
2732-2734 |
TO |
denotes |
to |
T10018 |
2735-2741 |
VB |
denotes |
result |
T10019 |
2742-2744 |
IN |
denotes |
in |
T10020 |
2745-2754 |
VBN |
denotes |
increased |
T10021 |
2755-2765 |
NN |
denotes |
inhibition |
T10022 |
2766-2773 |
IN |
denotes |
between |
T10023 |
2774-2777 |
DT |
denotes |
the |
T10024 |
2788-2795 |
NNS |
denotes |
neurons |
T10025 |
2778-2787 |
JJ |
denotes |
principal |
T10026 |
2796-2798 |
IN |
denotes |
in |
T10027 |
2799-2803 |
DT |
denotes |
this |
T10028 |
2804-2813 |
NN |
denotes |
structure |
T10029 |
2813-2814 |
. |
denotes |
. |
T10030 |
2814-2944 |
sentence |
denotes |
Notably, the improved olfactory discrimination capabilities were apparent even upon relatively small reductions in GluR-B levels. |
T10031 |
2815-2822 |
RB |
denotes |
Notably |
T10032 |
2875-2879 |
VBD |
denotes |
were |
T10033 |
2822-2824 |
, |
denotes |
, |
T10034 |
2824-2827 |
DT |
denotes |
the |
T10035 |
2862-2874 |
NNS |
denotes |
capabilities |
T10036 |
2828-2836 |
VBN |
denotes |
improved |
T10037 |
2837-2846 |
JJ |
denotes |
olfactory |
T10038 |
2847-2861 |
NN |
denotes |
discrimination |
T10039 |
2880-2888 |
JJ |
denotes |
apparent |
T10040 |
2889-2893 |
RB |
denotes |
even |
T10041 |
2894-2898 |
IN |
denotes |
upon |
T10042 |
2899-2909 |
RB |
denotes |
relatively |
T10043 |
2910-2915 |
JJ |
denotes |
small |
T10044 |
2916-2926 |
NNS |
denotes |
reductions |
T10045 |
2927-2929 |
IN |
denotes |
in |
T10046 |
2930-2934 |
NN |
denotes |
GluR |
T10047 |
2935-2936 |
NN |
denotes |
B |
T10048 |
2934-2935 |
HYPH |
denotes |
- |
T10049 |
2937-2943 |
NNS |
denotes |
levels |
T10050 |
2943-2944 |
. |
denotes |
. |
T10051 |
2944-3306 |
sentence |
denotes |
It will be interesting to see if GluR-B+/neo mice also exhibit enhanced odor discrimination, which is indeed likely given that low levels of GluR-B(Q), and hence a small increase in Ca2+-permeable AMPARs, arise from the attenuated GluR-Bneo allele [60], and, moreover, that GluR-B levels are decreased in these mice due to the single copy of the GluR-B+ allele. |
T10052 |
2945-2947 |
PRP |
denotes |
It |
T10053 |
2953-2955 |
VB |
denotes |
be |
T10054 |
2948-2952 |
MD |
denotes |
will |
T10055 |
2956-2967 |
JJ |
denotes |
interesting |
T10056 |
2968-2970 |
TO |
denotes |
to |
T10057 |
2971-2974 |
VB |
denotes |
see |
T10058 |
2975-2977 |
IN |
denotes |
if |
T10059 |
3000-3007 |
VBP |
denotes |
exhibit |
T10060 |
2978-2982 |
NN |
denotes |
GluR |
T10061 |
2983-2984 |
NN |
denotes |
B |
T10062 |
2982-2983 |
HYPH |
denotes |
- |
T10063 |
2990-2994 |
NNS |
denotes |
mice |
T10064 |
2984-2985 |
SYM |
denotes |
+ |
T10065 |
2985-2986 |
HYPH |
denotes |
/ |
T10066 |
2986-2989 |
NN |
denotes |
neo |
T10067 |
2995-2999 |
RB |
denotes |
also |
T10068 |
3008-3016 |
VBN |
denotes |
enhanced |
T10069 |
3022-3036 |
NN |
denotes |
discrimination |
T10070 |
3017-3021 |
NN |
denotes |
odor |
T10071 |
3036-3038 |
, |
denotes |
, |
T10072 |
3038-3043 |
WDT |
denotes |
which |
T10073 |
3044-3046 |
VBZ |
denotes |
is |
T10074 |
3047-3053 |
RB |
denotes |
indeed |
T10075 |
3054-3060 |
JJ |
denotes |
likely |
T10076 |
3061-3066 |
JJ |
denotes |
given |
T10077 |
3067-3071 |
IN |
denotes |
that |
T10078 |
3150-3155 |
VBP |
denotes |
arise |
T10079 |
3072-3075 |
JJ |
denotes |
low |
T10080 |
3076-3082 |
NNS |
denotes |
levels |
T10081 |
3083-3085 |
IN |
denotes |
of |
T10082 |
3086-3090 |
NN |
denotes |
GluR |
T10083 |
3093-3094 |
NN |
denotes |
Q |
T10084 |
3090-3091 |
HYPH |
denotes |
- |
T10085 |
3091-3092 |
NN |
denotes |
B |
T10086 |
3092-3093 |
-LRB- |
denotes |
( |
T10087 |
3094-3095 |
-RRB- |
denotes |
) |
T10088 |
3095-3097 |
, |
denotes |
, |
T10089 |
3097-3100 |
CC |
denotes |
and |
T10090 |
3101-3106 |
RB |
denotes |
hence |
T10091 |
3115-3123 |
NN |
denotes |
increase |
T10092 |
3107-3108 |
DT |
denotes |
a |
T10093 |
3109-3114 |
JJ |
denotes |
small |
T10094 |
3124-3126 |
IN |
denotes |
in |
T10095 |
3127-3130 |
NN |
denotes |
Ca2 |
T10096 |
3132-3141 |
JJ |
denotes |
permeable |
T10097 |
3130-3131 |
SYM |
denotes |
+ |
T10098 |
3131-3132 |
HYPH |
denotes |
- |
T10099 |
3142-3148 |
NNS |
denotes |
AMPARs |
T10100 |
3148-3150 |
, |
denotes |
, |
T10101 |
3156-3160 |
IN |
denotes |
from |
T10102 |
3161-3164 |
DT |
denotes |
the |
T10103 |
3186-3192 |
NN |
denotes |
allele |
T10104 |
3165-3175 |
VBN |
denotes |
attenuated |
T10105 |
3176-3180 |
NN |
denotes |
GluR |
T10106 |
3181-3185 |
NN |
denotes |
Bneo |
T10107 |
3180-3181 |
HYPH |
denotes |
- |
T10108 |
3193-3194 |
-LRB- |
denotes |
[ |
T10109 |
3194-3196 |
CD |
denotes |
60 |
T10110 |
3196-3197 |
-RRB- |
denotes |
] |
T10111 |
3197-3199 |
, |
denotes |
, |
T10112 |
3199-3202 |
CC |
denotes |
and |
T10113 |
3202-3204 |
, |
denotes |
, |
T10114 |
3204-3212 |
RB |
denotes |
moreover |
T10115 |
3237-3246 |
VBN |
denotes |
decreased |
T10116 |
3212-3214 |
, |
denotes |
, |
T10117 |
3214-3218 |
IN |
denotes |
that |
T10118 |
3219-3223 |
NN |
denotes |
GluR |
T10119 |
3224-3225 |
NN |
denotes |
B |
T10120 |
3223-3224 |
HYPH |
denotes |
- |
T10121 |
3226-3232 |
NNS |
denotes |
levels |
T10122 |
3233-3236 |
VBP |
denotes |
are |
T10123 |
3247-3249 |
IN |
denotes |
in |
T10124 |
3250-3255 |
DT |
denotes |
these |
T10125 |
3256-3260 |
NNS |
denotes |
mice |
T10126 |
3261-3264 |
IN |
denotes |
due |
T10127 |
3265-3267 |
IN |
denotes |
to |
T10128 |
3268-3271 |
DT |
denotes |
the |
T10129 |
3279-3283 |
NN |
denotes |
copy |
T10130 |
3272-3278 |
JJ |
denotes |
single |
T10131 |
3284-3286 |
IN |
denotes |
of |
T10132 |
3287-3290 |
DT |
denotes |
the |
T10133 |
3299-3305 |
NN |
denotes |
allele |
T10134 |
3291-3295 |
NN |
denotes |
GluR |
T10135 |
3296-3297 |
NN |
denotes |
B |
T10136 |
3295-3296 |
HYPH |
denotes |
- |
T10137 |
3297-3298 |
SYM |
denotes |
+ |
T10138 |
3305-3306 |
. |
denotes |
. |
T10139 |
3306-3616 |
sentence |
denotes |
In virtually all models of the olfactory bulb, lateral (and, in fewer models, also recurrent) inhibition plays a dominant role, either in establishing spatiotemporal dynamics [32,66–69], or in directly enhancing contrast and therefore simplifying discrimination and learning of similar odorants [24,28,29,36]. |
T10140 |
3307-3309 |
IN |
denotes |
In |
T10141 |
3412-3417 |
VBZ |
denotes |
plays |
T10142 |
3310-3319 |
RB |
denotes |
virtually |
T10143 |
3324-3330 |
NNS |
denotes |
models |
T10144 |
3320-3323 |
DT |
denotes |
all |
T10145 |
3331-3333 |
IN |
denotes |
of |
T10146 |
3334-3337 |
DT |
denotes |
the |
T10147 |
3348-3352 |
NN |
denotes |
bulb |
T10148 |
3338-3347 |
JJ |
denotes |
olfactory |
T10149 |
3352-3354 |
, |
denotes |
, |
T10150 |
3354-3361 |
JJ |
denotes |
lateral |
T10151 |
3401-3411 |
NN |
denotes |
inhibition |
T10152 |
3362-3363 |
-LRB- |
denotes |
( |
T10153 |
3363-3366 |
CC |
denotes |
and |
T10154 |
3366-3368 |
, |
denotes |
, |
T10155 |
3368-3370 |
IN |
denotes |
in |
T10156 |
3390-3399 |
JJ |
denotes |
recurrent |
T10157 |
3371-3376 |
JJR |
denotes |
fewer |
T10158 |
3377-3383 |
NNS |
denotes |
models |
T10159 |
3383-3385 |
, |
denotes |
, |
T10160 |
3385-3389 |
RB |
denotes |
also |
T10161 |
3399-3400 |
-RRB- |
denotes |
) |
T10162 |
3418-3419 |
DT |
denotes |
a |
T10163 |
3429-3433 |
NN |
denotes |
role |
T10164 |
3420-3428 |
JJ |
denotes |
dominant |
T10165 |
3433-3435 |
, |
denotes |
, |
T10166 |
3435-3441 |
CC |
denotes |
either |
T10167 |
3442-3444 |
IN |
denotes |
in |
T10168 |
3445-3457 |
VBG |
denotes |
establishing |
T10169 |
3458-3472 |
JJ |
denotes |
spatiotemporal |
T10170 |
3473-3481 |
NNS |
denotes |
dynamics |
T10171 |
3482-3483 |
-LRB- |
denotes |
[ |
T10172 |
3486-3488 |
CD |
denotes |
66 |
T10173 |
3483-3485 |
CD |
denotes |
32 |
T10174 |
3485-3486 |
, |
denotes |
, |
T10175 |
3488-3489 |
SYM |
denotes |
– |
T10176 |
3489-3491 |
CD |
denotes |
69 |
T10177 |
3491-3492 |
-RRB- |
denotes |
] |
T10178 |
3492-3494 |
, |
denotes |
, |
T10179 |
3494-3496 |
CC |
denotes |
or |
T10180 |
3497-3499 |
IN |
denotes |
in |
T10181 |
3500-3508 |
RB |
denotes |
directly |
T10182 |
3509-3518 |
VBG |
denotes |
enhancing |
T10183 |
3519-3527 |
NN |
denotes |
contrast |
T10184 |
3528-3531 |
CC |
denotes |
and |
T10185 |
3532-3541 |
RB |
denotes |
therefore |
T10186 |
3542-3553 |
VBG |
denotes |
simplifying |
T10187 |
3554-3568 |
NN |
denotes |
discrimination |
T10188 |
3569-3572 |
CC |
denotes |
and |
T10189 |
3573-3581 |
NN |
denotes |
learning |
T10190 |
3582-3584 |
IN |
denotes |
of |
T10191 |
3585-3592 |
JJ |
denotes |
similar |
T10192 |
3593-3601 |
NNS |
denotes |
odorants |
T10193 |
3602-3603 |
-LRB- |
denotes |
[ |
T10194 |
3612-3614 |
CD |
denotes |
36 |
T10195 |
3603-3605 |
CD |
denotes |
24 |
T10196 |
3605-3606 |
, |
denotes |
, |
T10197 |
3606-3608 |
CD |
denotes |
28 |
T10198 |
3608-3609 |
, |
denotes |
, |
T10199 |
3609-3611 |
CD |
denotes |
29 |
T10200 |
3611-3612 |
, |
denotes |
, |
T10201 |
3614-3615 |
-RRB- |
denotes |
] |
T10202 |
3615-3616 |
. |
denotes |
. |
T10203 |
3616-3808 |
sentence |
denotes |
Increased inhibition will thus in general improve discriminability, consistent with the behavioral improvements observed with GluR-B(Q) expression, the GluR-B knockout, and the “rescue” mice. |
T10204 |
3617-3626 |
VBN |
denotes |
Increased |
T10205 |
3627-3637 |
NN |
denotes |
inhibition |
T10206 |
3659-3666 |
VB |
denotes |
improve |
T10207 |
3638-3642 |
MD |
denotes |
will |
T10208 |
3643-3647 |
RB |
denotes |
thus |
T10209 |
3648-3650 |
IN |
denotes |
in |
T10210 |
3651-3658 |
JJ |
denotes |
general |
T10211 |
3667-3683 |
NN |
denotes |
discriminability |
T10212 |
3683-3685 |
, |
denotes |
, |
T10213 |
3685-3695 |
JJ |
denotes |
consistent |
T10214 |
3696-3700 |
IN |
denotes |
with |
T10215 |
3701-3704 |
DT |
denotes |
the |
T10216 |
3716-3728 |
NNS |
denotes |
improvements |
T10217 |
3705-3715 |
JJ |
denotes |
behavioral |
T10218 |
3729-3737 |
VBN |
denotes |
observed |
T10219 |
3738-3742 |
IN |
denotes |
with |
T10220 |
3743-3747 |
NN |
denotes |
GluR |
T10221 |
3750-3751 |
NN |
denotes |
Q |
T10222 |
3747-3748 |
HYPH |
denotes |
- |
T10223 |
3748-3749 |
NN |
denotes |
B |
T10224 |
3749-3750 |
-LRB- |
denotes |
( |
T10225 |
3753-3763 |
NN |
denotes |
expression |
T10226 |
3751-3752 |
-RRB- |
denotes |
) |
T10227 |
3763-3765 |
, |
denotes |
, |
T10228 |
3765-3768 |
DT |
denotes |
the |
T10229 |
3776-3784 |
NN |
denotes |
knockout |
T10230 |
3769-3773 |
NN |
denotes |
GluR |
T10231 |
3774-3775 |
NN |
denotes |
B |
T10232 |
3773-3774 |
HYPH |
denotes |
- |
T10233 |
3784-3786 |
, |
denotes |
, |
T10234 |
3786-3789 |
CC |
denotes |
and |
T10235 |
3790-3793 |
DT |
denotes |
the |
T10236 |
3803-3807 |
NNS |
denotes |
mice |
T10237 |
3794-3795 |
`` |
denotes |
“ |
T10238 |
3795-3801 |
NN |
denotes |
rescue |
T10239 |
3801-3802 |
'' |
denotes |
” |
T10240 |
3807-3808 |
. |
denotes |
. |
T10241 |
3808-4114 |
sentence |
denotes |
A direct test of this link would require the quantitative measurement of inhibition in the intact preparation, a task that might be feasible with further improved in vivo electrophysiological techniques, such as targeted recordings [70,71] or simultaneous pre- and postsynaptic intracellular measurements. |
T10242 |
3809-3810 |
DT |
denotes |
A |
T10243 |
3818-3822 |
NN |
denotes |
test |
T10244 |
3811-3817 |
JJ |
denotes |
direct |
T10245 |
3842-3849 |
VB |
denotes |
require |
T10246 |
3823-3825 |
IN |
denotes |
of |
T10247 |
3826-3830 |
DT |
denotes |
this |
T10248 |
3831-3835 |
NN |
denotes |
link |
T10249 |
3836-3841 |
MD |
denotes |
would |
T10250 |
3850-3853 |
DT |
denotes |
the |
T10251 |
3867-3878 |
NN |
denotes |
measurement |
T10252 |
3854-3866 |
JJ |
denotes |
quantitative |
T10253 |
3879-3881 |
IN |
denotes |
of |
T10254 |
3882-3892 |
NN |
denotes |
inhibition |
T10255 |
3893-3895 |
IN |
denotes |
in |
T10256 |
3896-3899 |
DT |
denotes |
the |
T10257 |
3907-3918 |
NN |
denotes |
preparation |
T10258 |
3900-3906 |
JJ |
denotes |
intact |
T10259 |
3918-3920 |
, |
denotes |
, |
T10260 |
3920-3921 |
DT |
denotes |
a |
T10261 |
3922-3926 |
NN |
denotes |
task |
T10262 |
3927-3931 |
WDT |
denotes |
that |
T10263 |
3938-3940 |
VB |
denotes |
be |
T10264 |
3932-3937 |
MD |
denotes |
might |
T10265 |
3941-3949 |
JJ |
denotes |
feasible |
T10266 |
3950-3954 |
IN |
denotes |
with |
T10267 |
3955-3962 |
RB |
denotes |
further |
T10268 |
3963-3971 |
VBN |
denotes |
improved |
T10269 |
4001-4011 |
NNS |
denotes |
techniques |
T10270 |
3972-3974 |
FW |
denotes |
in |
T10271 |
3975-3979 |
FW |
denotes |
vivo |
T10272 |
3980-4000 |
JJ |
denotes |
electrophysiological |
T10273 |
4011-4013 |
, |
denotes |
, |
T10274 |
4013-4017 |
JJ |
denotes |
such |
T10275 |
4018-4020 |
IN |
denotes |
as |
T10276 |
4021-4029 |
VBN |
denotes |
targeted |
T10277 |
4030-4040 |
NNS |
denotes |
recordings |
T10278 |
4041-4042 |
-LRB- |
denotes |
[ |
T10279 |
4045-4047 |
CD |
denotes |
71 |
T10280 |
4042-4044 |
CD |
denotes |
70 |
T10281 |
4044-4045 |
, |
denotes |
, |
T10282 |
4047-4048 |
-RRB- |
denotes |
] |
T10283 |
4049-4051 |
CC |
denotes |
or |
T10284 |
4052-4064 |
JJ |
denotes |
simultaneous |
T10285 |
4101-4113 |
NNS |
denotes |
measurements |
T10286 |
4065-4068 |
AFX |
denotes |
pre |
T10287 |
4074-4086 |
JJ |
denotes |
postsynaptic |
T10288 |
4068-4069 |
HYPH |
denotes |
- |
T10289 |
4070-4073 |
CC |
denotes |
and |
T10290 |
4087-4100 |
JJ |
denotes |
intracellular |
T10291 |
4113-4114 |
. |
denotes |
. |
R6103 |
T9487 |
T9488 |
amod |
Putative,Basis |
R6104 |
T9489 |
T9488 |
amod |
Cellular,Basis |
R6105 |
T9490 |
T9488 |
prep |
of,Basis |
R6106 |
T9491 |
T9492 |
amod |
Enhanced,Discrimination |
R6107 |
T9492 |
T9490 |
pobj |
Discrimination,of |
R6108 |
T9493 |
T9492 |
compound |
Odor,Discrimination |
R6109 |
T9494 |
T9492 |
cc |
and,Discrimination |
R6110 |
T9495 |
T9492 |
conj |
Learning,Discrimination |
R6111 |
T9497 |
T9498 |
compound |
AMPAR,properties |
R6112 |
T9498 |
T9499 |
nsubjpass |
properties,altered |
R6113 |
T9500 |
T9499 |
auxpass |
were,altered |
R6114 |
T9501 |
T9502 |
advmod |
specifically,in |
R6115 |
T9502 |
T9499 |
prep |
in,altered |
R6116 |
T9503 |
T9502 |
pobj |
neurons,in |
R6117 |
T9504 |
T9503 |
prep |
of,neurons |
R6118 |
T9505 |
T9506 |
compound |
forebrain,areas |
R6119 |
T9506 |
T9504 |
pobj |
areas,of |
R6120 |
T9507 |
T9506 |
punct |
", ",areas |
R6121 |
T9508 |
T9509 |
advmod |
most,notably |
R6122 |
T9509 |
T9510 |
advmod |
notably,bulb |
R6123 |
T9510 |
T9506 |
appos |
bulb,areas |
R6124 |
T9511 |
T9510 |
amod |
olfactory,bulb |
R6125 |
T9512 |
T9510 |
punct |
", ",bulb |
R6126 |
T9513 |
T9514 |
amod |
olfactory,cortex |
R6127 |
T9514 |
T9510 |
conj |
cortex,bulb |
R6128 |
T9515 |
T9514 |
punct |
", ",cortex |
R6129 |
T9516 |
T9514 |
cc |
and,cortex |
R6130 |
T9517 |
T9518 |
amod |
other,areas |
R6131 |
T9518 |
T9514 |
conj |
areas,cortex |
R6132 |
T9519 |
T9518 |
amod |
cortical,areas |
R6133 |
T9520 |
T9506 |
cc |
and,areas |
R6134 |
T9521 |
T9506 |
conj |
hippocampus,areas |
R6135 |
T9522 |
T9499 |
punct |
", ",altered |
R6136 |
T9523 |
T9499 |
advcl |
leading,altered |
R6137 |
T9524 |
T9523 |
prep |
to,leading |
R6138 |
T9525 |
T9526 |
amod |
enhanced,discrimination |
R6139 |
T9526 |
T9524 |
pobj |
discrimination,to |
R6140 |
T9527 |
T9526 |
compound |
odor,discrimination |
R6141 |
T9528 |
T9526 |
cc |
and,discrimination |
R6142 |
T9529 |
T9526 |
conj |
learning,discrimination |
R6143 |
T9530 |
T9499 |
punct |
.,altered |
R6144 |
T9532 |
T9533 |
advmod |
Interestingly,alter |
R6145 |
T9534 |
T9533 |
punct |
", ",alter |
R6146 |
T9535 |
T9536 |
amod |
transgenic,expression |
R6147 |
T9536 |
T9533 |
nsubj |
expression,alter |
R6148 |
T9537 |
T9536 |
prep |
of,expression |
R6149 |
T9538 |
T9539 |
compound |
GFPGluR,B |
R6150 |
T9539 |
T9537 |
pobj |
B,of |
R6151 |
T9540 |
T9539 |
punct |
-,B |
R6152 |
T9541 |
T9536 |
prep |
in,expression |
R6153 |
T9542 |
T9543 |
compound |
GluR,BΔFB |
R6154 |
T9543 |
T9545 |
compound |
BΔFB,mice |
R6155 |
T9544 |
T9543 |
punct |
-,BΔFB |
R6156 |
T9545 |
T9541 |
pobj |
mice,in |
R6157 |
T9546 |
T9547 |
punct |
(,rescue |
R6158 |
T9547 |
T9545 |
parataxis |
rescue,mice |
R6159 |
T9548 |
T9547 |
amod |
genetic,rescue |
R6160 |
T9549 |
T9547 |
punct |
“,rescue |
R6161 |
T9550 |
T9547 |
punct |
”,rescue |
R6162 |
T9551 |
T9547 |
punct |
),rescue |
R6163 |
T9552 |
T9536 |
punct |
", ",expression |
R6164 |
T9553 |
T9554 |
advmod |
specifically,in |
R6165 |
T9554 |
T9536 |
prep |
in,expression |
R6166 |
T9555 |
T9556 |
amod |
piriform,cortex |
R6167 |
T9556 |
T9554 |
pobj |
cortex,in |
R6168 |
T9557 |
T9556 |
cc |
and,cortex |
R6169 |
T9558 |
T9556 |
conj |
hippocampus,cortex |
R6170 |
T9559 |
T9556 |
prep |
with,cortex |
R6171 |
T9560 |
T9561 |
det |
no,expression |
R6172 |
T9561 |
T9559 |
pobj |
expression,with |
R6173 |
T9562 |
T9561 |
amod |
detectable,expression |
R6174 |
T9563 |
T9561 |
prep |
in,expression |
R6175 |
T9564 |
T9565 |
det |
the,bulb |
R6176 |
T9565 |
T9563 |
pobj |
bulb,in |
R6177 |
T9566 |
T9565 |
amod |
olfactory,bulb |
R6178 |
T9567 |
T9533 |
punct |
", ",alter |
R6179 |
T9568 |
T9533 |
aux |
did,alter |
R6180 |
T9569 |
T9533 |
neg |
not,alter |
R6181 |
T9570 |
T9571 |
amod |
enhanced,capabilities |
R6182 |
T9571 |
T9533 |
dobj |
capabilities,alter |
R6183 |
T9572 |
T9571 |
nmod |
discrimination,capabilities |
R6184 |
T9573 |
T9572 |
cc |
and,discrimination |
R6185 |
T9574 |
T9572 |
conj |
learning,discrimination |
R6186 |
T9575 |
T9533 |
punct |
.,alter |
R6187 |
T9577 |
T9578 |
nsubj |
This,is |
R6188 |
T9579 |
T9578 |
acomp |
consistent,is |
R6189 |
T9580 |
T9579 |
prep |
with,consistent |
R6190 |
T9581 |
T9582 |
det |
a,role |
R6191 |
T9582 |
T9580 |
pobj |
role,with |
R6192 |
T9583 |
T9582 |
amod |
primary,role |
R6193 |
T9584 |
T9582 |
prep |
of,role |
R6194 |
T9585 |
T9586 |
det |
the,bulb |
R6195 |
T9586 |
T9584 |
pobj |
bulb,of |
R6196 |
T9587 |
T9586 |
amod |
olfactory,bulb |
R6197 |
T9588 |
T9582 |
prep |
in,role |
R6198 |
T9589 |
T9590 |
amod |
olfactory,discrimination |
R6199 |
T9590 |
T9588 |
pobj |
discrimination,in |
R6200 |
T9591 |
T9590 |
cc |
and,discrimination |
R6201 |
T9592 |
T9590 |
conj |
learning,discrimination |
R6202 |
T9593 |
T9578 |
punct |
.,is |
R6203 |
T9595 |
T9596 |
advmod |
Alternatively,been |
R6204 |
T9597 |
T9596 |
punct |
", ",been |
R6205 |
T9598 |
T9599 |
amod |
transgenic,levels |
R6206 |
T9599 |
T9596 |
nsubj |
levels,been |
R6207 |
T9600 |
T9599 |
compound |
protein,levels |
R6208 |
T9601 |
T9596 |
aux |
might,been |
R6209 |
T9602 |
T9596 |
aux |
have,been |
R6210 |
T9603 |
T9604 |
advmod |
too,low |
R6211 |
T9604 |
T9596 |
acomp |
low,been |
R6212 |
T9605 |
T9606 |
aux |
to,alter |
R6213 |
T9606 |
T9604 |
xcomp |
alter,low |
R6214 |
T9607 |
T9608 |
nmod |
discrimination,capabilities |
R6215 |
T9608 |
T9606 |
dobj |
capabilities,alter |
R6216 |
T9609 |
T9607 |
cc |
and,discrimination |
R6217 |
T9610 |
T9607 |
conj |
learning,discrimination |
R6218 |
T9611 |
T9596 |
punct |
", ",been |
R6219 |
T9612 |
T9613 |
mark |
although,affected |
R6220 |
T9613 |
T9596 |
advcl |
affected,been |
R6221 |
T9614 |
T9613 |
nsubjpass |
memory,affected |
R6222 |
T9615 |
T9613 |
auxpass |
was,affected |
R6223 |
T9616 |
T9613 |
advmod |
clearly,affected |
R6224 |
T9617 |
T9596 |
punct |
.,been |
R6225 |
T9619 |
T9620 |
det |
This,notion |
R6226 |
T9620 |
T9621 |
nsubjpass |
notion,tested |
R6227 |
T9622 |
T9621 |
aux |
will,tested |
R6228 |
T9623 |
T9621 |
auxpass |
be,tested |
R6229 |
T9624 |
T9621 |
advmod |
further,tested |
R6230 |
T9625 |
T9621 |
prep |
in,tested |
R6231 |
T9626 |
T9625 |
pobj |
mice,in |
R6232 |
T9627 |
T9626 |
prep |
with,mice |
R6233 |
T9628 |
T9629 |
amod |
piriform,cortex |
R6234 |
T9629 |
T9630 |
npadvmod |
cortex,specific |
R6235 |
T9630 |
T9632 |
amod |
specific,ablation |
R6236 |
T9631 |
T9630 |
punct |
-,specific |
R6237 |
T9632 |
T9627 |
pobj |
ablation,with |
R6238 |
T9633 |
T9634 |
compound |
GluR,B |
R6239 |
T9634 |
T9632 |
compound |
B,ablation |
R6240 |
T9635 |
T9634 |
punct |
-,B |
R6241 |
T9636 |
T9621 |
punct |
.,tested |
R6242 |
T9638 |
T9639 |
det |
A,contribution |
R6243 |
T9639 |
T9641 |
nsubj |
contribution,seems |
R6244 |
T9640 |
T9639 |
amod |
direct,contribution |
R6245 |
T9642 |
T9639 |
prep |
to,contribution |
R6246 |
T9643 |
T9644 |
det |
the,phenotype |
R6247 |
T9644 |
T9642 |
pobj |
phenotype,to |
R6248 |
T9645 |
T9639 |
prep |
by,contribution |
R6249 |
T9646 |
T9647 |
nmod |
Ca2,influx |
R6250 |
T9647 |
T9645 |
pobj |
influx,by |
R6251 |
T9648 |
T9646 |
punct |
+,Ca2 |
R6252 |
T9649 |
T9647 |
prep |
through,influx |
R6253 |
T9650 |
T9651 |
advmod |
genetically,modified |
R6254 |
T9651 |
T9652 |
amod |
modified,channels |
R6255 |
T9652 |
T9649 |
pobj |
channels,through |
R6256 |
T9653 |
T9652 |
compound |
AMPA,channels |
R6257 |
T9654 |
T9655 |
aux |
to,be |
R6258 |
T9655 |
T9641 |
xcomp |
be,seems |
R6259 |
T9656 |
T9655 |
acomp |
likely,be |
R6260 |
T9657 |
T9641 |
punct |
", ",seems |
R6261 |
T9658 |
T9659 |
mark |
since,showed |
R6262 |
T9659 |
T9641 |
advcl |
showed,seems |
R6263 |
T9660 |
T9659 |
nsubj |
mice,showed |
R6264 |
T9661 |
T9660 |
acl |
expressing,mice |
R6265 |
T9662 |
T9663 |
nmod |
Q,R |
R6266 |
T9663 |
T9665 |
nmod |
R,B |
R6267 |
T9664 |
T9663 |
punct |
/,R |
R6268 |
T9665 |
T9661 |
dobj |
B,expressing |
R6269 |
T9666 |
T9667 |
npadvmod |
site,unedited |
R6270 |
T9667 |
T9665 |
amod |
unedited,B |
R6271 |
T9668 |
T9667 |
punct |
-,unedited |
R6272 |
T9669 |
T9665 |
compound |
GluR,B |
R6273 |
T9670 |
T9665 |
punct |
-,B |
R6274 |
T9671 |
T9672 |
advmod |
even,better |
R6275 |
T9672 |
T9673 |
amod |
better,performance |
R6276 |
T9673 |
T9659 |
dobj |
performance,showed |
R6277 |
T9674 |
T9675 |
nmod |
odor,learning |
R6278 |
T9675 |
T9673 |
nmod |
learning,performance |
R6279 |
T9676 |
T9675 |
cc |
and,learning |
R6280 |
T9677 |
T9675 |
conj |
discrimination,learning |
R6281 |
T9678 |
T9659 |
prep |
compared,showed |
R6282 |
T9679 |
T9678 |
prep |
with,compared |
R6283 |
T9680 |
T9679 |
pobj |
mice,with |
R6284 |
T9681 |
T9680 |
prep |
with,mice |
R6285 |
T9682 |
T9683 |
amod |
depleted,B |
R6286 |
T9683 |
T9681 |
pobj |
B,with |
R6287 |
T9684 |
T9683 |
compound |
GluR,B |
R6288 |
T9685 |
T9683 |
punct |
-,B |
R6289 |
T9686 |
T9641 |
punct |
.,seems |
R6290 |
T9688 |
T9689 |
prep |
In,increased |
R6291 |
T9690 |
T9691 |
det |
both,models |
R6292 |
T9691 |
T9688 |
pobj |
models,In |
R6293 |
T9692 |
T9691 |
compound |
mouse,models |
R6294 |
T9693 |
T9694 |
nmod |
Ca2,influx |
R6295 |
T9694 |
T9689 |
nsubjpass |
influx,increased |
R6296 |
T9695 |
T9693 |
punct |
+,Ca2 |
R6297 |
T9696 |
T9694 |
prep |
through,influx |
R6298 |
T9697 |
T9698 |
compound |
AMPA,channels |
R6299 |
T9698 |
T9696 |
pobj |
channels,through |
R6300 |
T9699 |
T9689 |
auxpass |
is,increased |
R6301 |
T9700 |
T9689 |
punct |
", ",increased |
R6302 |
T9701 |
T9702 |
mark |
whereas,differs |
R6303 |
T9702 |
T9689 |
advcl |
differs,increased |
R6304 |
T9703 |
T9704 |
det |
the,effect |
R6305 |
T9704 |
T9702 |
nsubj |
effect,differs |
R6306 |
T9705 |
T9704 |
prep |
on,effect |
R6307 |
T9706 |
T9707 |
det |
the,conductance |
R6308 |
T9707 |
T9705 |
pobj |
conductance,on |
R6309 |
T9708 |
T9707 |
amod |
macroscopic,conductance |
R6310 |
T9709 |
T9707 |
compound |
AMPA,conductance |
R6311 |
T9710 |
T9689 |
punct |
.,increased |
R6312 |
T9712 |
T9713 |
compound |
AMPAR,currents |
R6313 |
T9713 |
T9714 |
nsubjpass |
currents,reduced |
R6314 |
T9715 |
T9714 |
auxpass |
are,reduced |
R6315 |
T9716 |
T9714 |
prep |
in,reduced |
R6316 |
T9717 |
T9716 |
pobj |
mice,in |
R6317 |
T9718 |
T9719 |
neg |
not,expressing |
R6318 |
T9719 |
T9717 |
acl |
expressing,mice |
R6319 |
T9720 |
T9721 |
compound |
GluR,B |
R6320 |
T9721 |
T9719 |
dobj |
B,expressing |
R6321 |
T9722 |
T9721 |
punct |
-,B |
R6322 |
T9723 |
T9724 |
punct |
[,51 |
R6323 |
T9724 |
T9714 |
parataxis |
51,reduced |
R6324 |
T9725 |
T9724 |
punct |
],51 |
R6325 |
T9726 |
T9714 |
punct |
", ",reduced |
R6326 |
T9727 |
T9728 |
advmod |
possibly,due |
R6327 |
T9728 |
T9714 |
prep |
due,reduced |
R6328 |
T9729 |
T9728 |
pcomp |
to,due |
R6329 |
T9730 |
T9731 |
amod |
fewer,channels |
R6330 |
T9731 |
T9728 |
pobj |
channels,due |
R6331 |
T9732 |
T9731 |
amod |
synaptic,channels |
R6332 |
T9733 |
T9731 |
compound |
AMPA,channels |
R6333 |
T9734 |
T9731 |
cc |
and,channels |
R6334 |
T9735 |
T9736 |
amod |
impaired,trafficking |
R6335 |
T9736 |
T9731 |
conj |
trafficking,channels |
R6336 |
T9737 |
T9736 |
compound |
AMPAR,trafficking |
R6337 |
T9738 |
T9736 |
cc |
and,trafficking |
R6338 |
T9739 |
T9736 |
conj |
recycling,trafficking |
R6339 |
T9740 |
T9714 |
punct |
.,reduced |
R6340 |
T9742 |
T9743 |
prep |
In,increased |
R6341 |
T9744 |
T9742 |
pobj |
mice,In |
R6342 |
T9745 |
T9744 |
acl |
expressing,mice |
R6343 |
T9746 |
T9747 |
det |
the,form |
R6344 |
T9747 |
T9745 |
dobj |
form,expressing |
R6345 |
T9748 |
T9747 |
amod |
unedited,form |
R6346 |
T9749 |
T9747 |
prep |
of,form |
R6347 |
T9750 |
T9751 |
nmod |
GluR,Q |
R6348 |
T9751 |
T9749 |
pobj |
Q,of |
R6349 |
T9752 |
T9751 |
punct |
-,Q |
R6350 |
T9753 |
T9751 |
nmod |
B,Q |
R6351 |
T9754 |
T9751 |
punct |
(,Q |
R6352 |
T9755 |
T9751 |
punct |
),Q |
R6353 |
T9756 |
T9743 |
punct |
", ",increased |
R6354 |
T9757 |
T9758 |
amod |
macroscopic,conductance |
R6355 |
T9758 |
T9743 |
nsubjpass |
conductance,increased |
R6356 |
T9759 |
T9758 |
prep |
in,conductance |
R6357 |
T9760 |
T9761 |
amod |
whole,cell |
R6358 |
T9761 |
T9763 |
compound |
cell,patches |
R6359 |
T9762 |
T9761 |
punct |
-,cell |
R6360 |
T9763 |
T9759 |
pobj |
patches,in |
R6361 |
T9764 |
T9763 |
prep |
of,patches |
R6362 |
T9765 |
T9766 |
compound |
CA1,pyramidals |
R6363 |
T9766 |
T9764 |
pobj |
pyramidals,of |
R6364 |
T9767 |
T9743 |
auxpass |
is,increased |
R6365 |
T9768 |
T9769 |
punct |
[,60 |
R6366 |
T9769 |
T9743 |
parataxis |
60,increased |
R6367 |
T9770 |
T9769 |
punct |
],60 |
R6368 |
T9771 |
T9743 |
punct |
", ",increased |
R6369 |
T9772 |
T9743 |
cc |
but,increased |
R6370 |
T9773 |
T9774 |
amod |
excitatory,transmission |
R6371 |
T9774 |
T9775 |
nsubj |
transmission,is |
R6372 |
T9775 |
T9743 |
conj |
is,increased |
R6373 |
T9776 |
T9774 |
prep |
in,transmission |
R6374 |
T9777 |
T9778 |
nmod |
CA3,synapses |
R6375 |
T9778 |
T9776 |
pobj |
synapses,in |
R6376 |
T9779 |
T9777 |
punct |
-,CA3 |
R6377 |
T9780 |
T9777 |
prep |
to,CA3 |
R6378 |
T9781 |
T9780 |
punct |
-,to |
R6379 |
T9782 |
T9780 |
pobj |
CA1,to |
R6380 |
T9783 |
T9778 |
compound |
cell,synapses |
R6381 |
T9784 |
T9785 |
advmod |
somewhat,reduced |
R6382 |
T9785 |
T9775 |
acomp |
reduced,is |
R6383 |
T9786 |
T9775 |
punct |
", ",is |
R6384 |
T9787 |
T9775 |
prep |
in,is |
R6385 |
T9788 |
T9787 |
pobj |
spite,in |
R6386 |
T9789 |
T9788 |
prep |
of,spite |
R6387 |
T9790 |
T9791 |
det |
a,threshold |
R6388 |
T9791 |
T9789 |
pobj |
threshold,of |
R6389 |
T9792 |
T9791 |
amod |
lower,threshold |
R6390 |
T9793 |
T9791 |
prep |
for,threshold |
R6391 |
T9794 |
T9793 |
pcomp |
generating,for |
R6392 |
T9795 |
T9796 |
det |
a,spike |
R6393 |
T9796 |
T9794 |
dobj |
spike,generating |
R6394 |
T9797 |
T9796 |
compound |
population,spike |
R6395 |
T9798 |
T9799 |
punct |
[,58 |
R6396 |
T9799 |
T9775 |
parataxis |
58,is |
R6397 |
T9800 |
T9799 |
punct |
],58 |
R6398 |
T9801 |
T9743 |
punct |
", ",increased |
R6399 |
T9802 |
T9743 |
advcl |
indicating,increased |
R6400 |
T9803 |
T9804 |
amod |
increased,excitability |
R6401 |
T9804 |
T9802 |
dobj |
excitability,indicating |
R6402 |
T9805 |
T9804 |
amod |
synaptic,excitability |
R6403 |
T9806 |
T9802 |
prep |
by,indicating |
R6404 |
T9807 |
T9808 |
amod |
sustained,expression |
R6405 |
T9808 |
T9806 |
pobj |
expression,by |
R6406 |
T9809 |
T9810 |
nmod |
GluR,Q |
R6407 |
T9810 |
T9808 |
nmod |
Q,expression |
R6408 |
T9811 |
T9810 |
punct |
-,Q |
R6409 |
T9812 |
T9810 |
nmod |
B,Q |
R6410 |
T9813 |
T9810 |
punct |
(,Q |
R6411 |
T9814 |
T9810 |
punct |
),Q |
R6412 |
T9815 |
T9802 |
punct |
", ",indicating |
R6413 |
T9816 |
T9802 |
prep |
in,indicating |
R6414 |
T9817 |
T9816 |
pobj |
line,in |
R6415 |
T9818 |
T9817 |
prep |
with,line |
R6416 |
T9819 |
T9820 |
det |
the,phenotype |
R6417 |
T9820 |
T9818 |
pobj |
phenotype,with |
R6418 |
T9821 |
T9822 |
npadvmod |
seizure,prone |
R6419 |
T9822 |
T9820 |
amod |
prone,phenotype |
R6420 |
T9823 |
T9822 |
punct |
-,prone |
R6421 |
T9824 |
T9743 |
punct |
.,increased |
R6422 |
T9826 |
T9827 |
advmod |
Yet,yield |
R6423 |
T9828 |
T9827 |
punct |
", ",yield |
R6424 |
T9829 |
T9830 |
det |
both,models |
R6425 |
T9830 |
T9827 |
nsubj |
models,yield |
R6426 |
T9831 |
T9830 |
compound |
mouse,models |
R6427 |
T9832 |
T9833 |
amod |
enhanced,capability |
R6428 |
T9833 |
T9827 |
dobj |
capability,yield |
R6429 |
T9834 |
T9833 |
nmod |
discrimination,capability |
R6430 |
T9835 |
T9834 |
cc |
and,discrimination |
R6431 |
T9836 |
T9834 |
conj |
learning,discrimination |
R6432 |
T9837 |
T9827 |
punct |
.,yield |
R6433 |
T9839 |
T9840 |
det |
The,phenotype |
R6434 |
T9840 |
T9842 |
nsubjpass |
phenotype,attributed |
R6435 |
T9841 |
T9840 |
amod |
milder,phenotype |
R6436 |
T9843 |
T9840 |
prep |
upon,phenotype |
R6437 |
T9844 |
T9845 |
compound |
GluR,B |
R6438 |
T9845 |
T9847 |
compound |
B,depletion |
R6439 |
T9846 |
T9845 |
punct |
-,B |
R6440 |
T9847 |
T9843 |
pobj |
depletion,upon |
R6441 |
T9848 |
T9842 |
aux |
could,attributed |
R6442 |
T9849 |
T9842 |
auxpass |
be,attributed |
R6443 |
T9850 |
T9842 |
prep |
to,attributed |
R6444 |
T9851 |
T9852 |
amod |
reduced,densities |
R6445 |
T9852 |
T9850 |
pobj |
densities,to |
R6446 |
T9853 |
T9852 |
compound |
AMPAR,densities |
R6447 |
T9854 |
T9852 |
prep |
at,densities |
R6448 |
T9855 |
T9854 |
pobj |
synapses,at |
R6449 |
T9856 |
T9857 |
punct |
[,41 |
R6450 |
T9857 |
T9852 |
parataxis |
41,densities |
R6451 |
T9858 |
T9857 |
nummod |
40,41 |
R6452 |
T9859 |
T9857 |
punct |
",",41 |
R6453 |
T9860 |
T9857 |
punct |
],41 |
R6454 |
T9861 |
T9850 |
cc |
and,to |
R6455 |
T9862 |
T9863 |
advmod |
therefore,to |
R6456 |
T9863 |
T9850 |
conj |
to,to |
R6457 |
T9864 |
T9863 |
advmod |
probably,to |
R6458 |
T9865 |
T9866 |
det |
a,extent |
R6459 |
T9866 |
T9863 |
pobj |
extent,to |
R6460 |
T9867 |
T9866 |
amod |
lesser,extent |
R6461 |
T9868 |
T9866 |
prep |
of,extent |
R6462 |
T9869 |
T9870 |
nmod |
Ca2,influx |
R6463 |
T9870 |
T9868 |
pobj |
influx,of |
R6464 |
T9871 |
T9869 |
punct |
+,Ca2 |
R6465 |
T9872 |
T9842 |
punct |
.,attributed |
R6466 |
T9874 |
T9875 |
nsubjpass |
This,supported |
R6467 |
T9876 |
T9875 |
auxpass |
is,supported |
R6468 |
T9877 |
T9875 |
advmod |
further,supported |
R6469 |
T9878 |
T9875 |
agent |
by,supported |
R6470 |
T9879 |
T9880 |
npadvmod |
kainate,induced |
R6471 |
T9880 |
T9882 |
amod |
induced,uptake |
R6472 |
T9881 |
T9880 |
punct |
-,induced |
R6473 |
T9882 |
T9878 |
pobj |
uptake,by |
R6474 |
T9883 |
T9882 |
nmod |
Co2,uptake |
R6475 |
T9884 |
T9883 |
punct |
+,Co2 |
R6476 |
T9885 |
T9875 |
prep |
in,supported |
R6477 |
T9886 |
T9887 |
amod |
acute,slices |
R6478 |
T9887 |
T9885 |
pobj |
slices,in |
R6479 |
T9888 |
T9887 |
compound |
brain,slices |
R6480 |
T9889 |
T9875 |
punct |
", ",supported |
R6481 |
T9890 |
T9875 |
advcl |
revealing,supported |
R6482 |
T9891 |
T9892 |
advmod |
considerably,higher |
R6483 |
T9892 |
T9893 |
amod |
higher,uptake |
R6484 |
T9893 |
T9890 |
dobj |
uptake,revealing |
R6485 |
T9894 |
T9893 |
nmod |
Co2,uptake |
R6486 |
T9895 |
T9894 |
punct |
+,Co2 |
R6487 |
T9896 |
T9893 |
prep |
via,uptake |
R6488 |
T9897 |
T9898 |
npadvmod |
Ca2,permeable |
R6489 |
T9898 |
T9901 |
amod |
permeable,AMPARs |
R6490 |
T9899 |
T9897 |
punct |
+,Ca2 |
R6491 |
T9900 |
T9898 |
punct |
-,permeable |
R6492 |
T9901 |
T9896 |
pobj |
AMPARs,via |
R6493 |
T9902 |
T9890 |
prep |
in,revealing |
R6494 |
T9903 |
T9904 |
amod |
hippocampal,neurons |
R6495 |
T9904 |
T9902 |
pobj |
neurons,in |
R6496 |
T9905 |
T9904 |
amod |
pyramidal,neurons |
R6497 |
T9906 |
T9904 |
prep |
of,neurons |
R6498 |
T9907 |
T9906 |
pobj |
mice,of |
R6499 |
T9908 |
T9907 |
acl |
expressing,mice |
R6500 |
T9909 |
T9910 |
compound |
GluR,B |
R6501 |
T9910 |
T9908 |
dobj |
B,expressing |
R6502 |
T9911 |
T9910 |
punct |
-,B |
R6503 |
T9912 |
T9913 |
punct |
(,Q |
R6504 |
T9913 |
T9908 |
parataxis |
Q,expressing |
R6505 |
T9914 |
T9913 |
punct |
),Q |
R6506 |
T9915 |
T9890 |
punct |
", ",revealing |
R6507 |
T9916 |
T9890 |
prep |
than,revealing |
R6508 |
T9917 |
T9916 |
pobj |
those,than |
R6509 |
T9918 |
T9917 |
acl |
lacking,those |
R6510 |
T9919 |
T9920 |
compound |
GluR,B |
R6511 |
T9920 |
T9918 |
dobj |
B,lacking |
R6512 |
T9921 |
T9920 |
punct |
-,B |
R6513 |
T9922 |
T9923 |
punct |
(,data |
R6514 |
T9923 |
T9875 |
parataxis |
data,supported |
R6515 |
T9924 |
T9923 |
dep |
DRS,data |
R6516 |
T9925 |
T9924 |
punct |
", ",DRS |
R6517 |
T9926 |
T9924 |
conj |
RS,DRS |
R6518 |
T9927 |
T9926 |
punct |
", ",RS |
R6519 |
T9928 |
T9926 |
cc |
and,RS |
R6520 |
T9929 |
T9926 |
conj |
PHS,RS |
R6521 |
T9930 |
T9923 |
punct |
", ",data |
R6522 |
T9931 |
T9923 |
amod |
unpublished,data |
R6523 |
T9932 |
T9923 |
punct |
),data |
R6524 |
T9933 |
T9875 |
punct |
.,supported |
R6525 |
T9935 |
T9936 |
advmod |
Normally,localized |
R6526 |
T9937 |
T9936 |
punct |
", ",localized |
R6527 |
T9938 |
T9939 |
compound |
GluR,B |
R6528 |
T9939 |
T9941 |
npadvmod |
B,containing |
R6529 |
T9940 |
T9939 |
punct |
-,B |
R6530 |
T9941 |
T9943 |
amod |
containing,AMPARs |
R6531 |
T9942 |
T9941 |
punct |
-,containing |
R6532 |
T9943 |
T9936 |
nsubjpass |
AMPARs,localized |
R6533 |
T9944 |
T9936 |
auxpass |
are,localized |
R6534 |
T9945 |
T9936 |
advmod |
prominently,localized |
R6535 |
T9946 |
T9936 |
prep |
at,localized |
R6536 |
T9947 |
T9948 |
det |
the,synapse |
R6537 |
T9948 |
T9946 |
pobj |
synapse,at |
R6538 |
T9949 |
T9948 |
amod |
dendrodendritic,synapse |
R6539 |
T9950 |
T9936 |
prep |
between,localized |
R6540 |
T9951 |
T9952 |
amod |
mitral,cells |
R6541 |
T9952 |
T9950 |
pobj |
cells,between |
R6542 |
T9953 |
T9951 |
cc |
and,mitral |
R6543 |
T9954 |
T9951 |
conj |
granule,mitral |
R6544 |
T9955 |
T9936 |
prep |
in,localized |
R6545 |
T9956 |
T9957 |
det |
the,bulb |
R6546 |
T9957 |
T9955 |
pobj |
bulb,in |
R6547 |
T9958 |
T9957 |
amod |
olfactory,bulb |
R6548 |
T9959 |
T9960 |
punct |
[,65 |
R6549 |
T9960 |
T9936 |
parataxis |
65,localized |
R6550 |
T9961 |
T9960 |
nummod |
64,65 |
R6551 |
T9962 |
T9960 |
punct |
",",65 |
R6552 |
T9963 |
T9960 |
punct |
],65 |
R6553 |
T9964 |
T9936 |
punct |
.,localized |
R6554 |
T9966 |
T9967 |
mark |
As,thought |
R6555 |
T9967 |
T9975 |
advcl |
thought,is |
R6556 |
T9968 |
T9969 |
nmod |
Ca2,influx |
R6557 |
T9969 |
T9967 |
nsubjpass |
influx,thought |
R6558 |
T9970 |
T9968 |
punct |
+,Ca2 |
R6559 |
T9971 |
T9969 |
prep |
through,influx |
R6560 |
T9972 |
T9973 |
compound |
glutamate,receptors |
R6561 |
T9973 |
T9971 |
pobj |
receptors,through |
R6562 |
T9974 |
T9967 |
auxpass |
is,thought |
R6563 |
T9976 |
T9977 |
aux |
to,contribute |
R6564 |
T9977 |
T9967 |
xcomp |
contribute,thought |
R6565 |
T9978 |
T9977 |
prep |
to,contribute |
R6566 |
T9979 |
T9980 |
amod |
lateral,inhibition |
R6567 |
T9980 |
T9978 |
pobj |
inhibition,to |
R6568 |
T9981 |
T9979 |
cc |
and,lateral |
R6569 |
T9982 |
T9979 |
conj |
recurrent,lateral |
R6570 |
T9983 |
T9984 |
punct |
(,38 |
R6571 |
T9984 |
T9977 |
parataxis |
38,contribute |
R6572 |
T9985 |
T9984 |
punct |
[,38 |
R6573 |
T9986 |
T9984 |
punct |
],38 |
R6574 |
T9987 |
T9984 |
advcl |
see,38 |
R6575 |
T9988 |
T9987 |
advmod |
also,see |
R6576 |
T9989 |
T9987 |
punct |
[,see |
R6577 |
T9990 |
T9987 |
dobj |
39,see |
R6578 |
T9991 |
T9984 |
punct |
],38 |
R6579 |
T9992 |
T9984 |
punct |
),38 |
R6580 |
T9993 |
T9975 |
punct |
", ",is |
R6581 |
T9994 |
T9995 |
det |
the,absence |
R6582 |
T9995 |
T9975 |
nsubj |
absence,is |
R6583 |
T9996 |
T9995 |
prep |
of,absence |
R6584 |
T9997 |
T9998 |
compound |
GluR,B |
R6585 |
T9998 |
T9996 |
pobj |
B,of |
R6586 |
T9999 |
T9998 |
punct |
-,B |
R6587 |
T10000 |
T9995 |
punct |
", ",absence |
R6588 |
T10001 |
T9995 |
cc |
or,absence |
R6589 |
T10002 |
T10003 |
det |
the,presence |
R6590 |
T10003 |
T9995 |
conj |
presence,absence |
R6591 |
T10004 |
T10003 |
prep |
of,presence |
R6592 |
T10005 |
T10006 |
compound |
GluR,B |
R6593 |
T10006 |
T10004 |
pobj |
B,of |
R6594 |
T10007 |
T10006 |
punct |
-,B |
R6595 |
T10008 |
T10009 |
punct |
(,Q |
R6596 |
T10009 |
T10003 |
parataxis |
Q,presence |
R6597 |
T10010 |
T10009 |
punct |
),Q |
R6598 |
T10011 |
T9995 |
prep |
in,absence |
R6599 |
T10012 |
T10013 |
det |
the,bulb |
R6600 |
T10013 |
T10011 |
pobj |
bulb,in |
R6601 |
T10014 |
T10013 |
amod |
olfactory,bulb |
R6602 |
T10015 |
T9975 |
punct |
", ",is |
R6603 |
T10016 |
T9975 |
acomp |
likely,is |
R6604 |
T10017 |
T10018 |
aux |
to,result |
R6605 |
T10018 |
T10016 |
xcomp |
result,likely |
R6606 |
T10019 |
T10018 |
prep |
in,result |
R6607 |
T10020 |
T10021 |
amod |
increased,inhibition |
R6608 |
T10021 |
T10019 |
pobj |
inhibition,in |
R6609 |
T10022 |
T10021 |
prep |
between,inhibition |
R6610 |
T10023 |
T10024 |
det |
the,neurons |
R6611 |
T10024 |
T10022 |
pobj |
neurons,between |
R6612 |
T10025 |
T10024 |
amod |
principal,neurons |
R6613 |
T10026 |
T10024 |
prep |
in,neurons |
R6614 |
T10027 |
T10028 |
det |
this,structure |
R6615 |
T10028 |
T10026 |
pobj |
structure,in |
R6616 |
T10029 |
T9975 |
punct |
.,is |
R6617 |
T10031 |
T10032 |
advmod |
Notably,were |
R6618 |
T10033 |
T10032 |
punct |
", ",were |
R6619 |
T10034 |
T10035 |
det |
the,capabilities |
R6620 |
T10035 |
T10032 |
nsubj |
capabilities,were |
R6621 |
T10036 |
T10035 |
amod |
improved,capabilities |
R6622 |
T10037 |
T10038 |
amod |
olfactory,discrimination |
R6623 |
T10038 |
T10035 |
compound |
discrimination,capabilities |
R6624 |
T10039 |
T10032 |
acomp |
apparent,were |
R6625 |
T10040 |
T10041 |
advmod |
even,upon |
R6626 |
T10041 |
T10032 |
prep |
upon,were |
R6627 |
T10042 |
T10043 |
advmod |
relatively,small |
R6628 |
T10043 |
T10044 |
amod |
small,reductions |
R6629 |
T10044 |
T10041 |
pobj |
reductions,upon |
R6630 |
T10045 |
T10044 |
prep |
in,reductions |
R6631 |
T10046 |
T10047 |
compound |
GluR,B |
R6632 |
T10047 |
T10049 |
compound |
B,levels |
R6633 |
T10048 |
T10047 |
punct |
-,B |
R6634 |
T10049 |
T10045 |
pobj |
levels,in |
R6635 |
T10050 |
T10032 |
punct |
.,were |
R6636 |
T10052 |
T10053 |
nsubj |
It,be |
R6637 |
T10054 |
T10053 |
aux |
will,be |
R6638 |
T10055 |
T10053 |
acomp |
interesting,be |
R6639 |
T10056 |
T10057 |
aux |
to,see |
R6640 |
T10057 |
T10053 |
xcomp |
see,be |
R6641 |
T10058 |
T10059 |
mark |
if,exhibit |
R6642 |
T10059 |
T10057 |
ccomp |
exhibit,see |
R6643 |
T10060 |
T10061 |
nmod |
GluR,B |
R6644 |
T10061 |
T10063 |
nmod |
B,mice |
R6645 |
T10062 |
T10061 |
punct |
-,B |
R6646 |
T10063 |
T10059 |
nsubj |
mice,exhibit |
R6647 |
T10064 |
T10061 |
punct |
+,B |
R6648 |
T10065 |
T10061 |
punct |
/,B |
R6649 |
T10066 |
T10061 |
appos |
neo,B |
R6650 |
T10067 |
T10059 |
advmod |
also,exhibit |
R6651 |
T10068 |
T10069 |
amod |
enhanced,discrimination |
R6652 |
T10069 |
T10059 |
dobj |
discrimination,exhibit |
R6653 |
T10070 |
T10069 |
compound |
odor,discrimination |
R6654 |
T10071 |
T10059 |
punct |
", ",exhibit |
R6655 |
T10072 |
T10073 |
dep |
which,is |
R6656 |
T10073 |
T10059 |
advcl |
is,exhibit |
R6657 |
T10074 |
T10073 |
advmod |
indeed,is |
R6658 |
T10075 |
T10073 |
acomp |
likely,is |
R6659 |
T10076 |
T10073 |
prep |
given,is |
R6660 |
T10077 |
T10078 |
mark |
that,arise |
R6661 |
T10078 |
T10076 |
pcomp |
arise,given |
R6662 |
T10079 |
T10080 |
amod |
low,levels |
R6663 |
T10080 |
T10078 |
nsubj |
levels,arise |
R6664 |
T10081 |
T10080 |
prep |
of,levels |
R6665 |
T10082 |
T10083 |
nmod |
GluR,Q |
R6666 |
T10083 |
T10081 |
pobj |
Q,of |
R6667 |
T10084 |
T10083 |
punct |
-,Q |
R6668 |
T10085 |
T10083 |
nmod |
B,Q |
R6669 |
T10086 |
T10083 |
punct |
(,Q |
R6670 |
T10087 |
T10083 |
punct |
),Q |
R6671 |
T10088 |
T10080 |
punct |
", ",levels |
R6672 |
T10089 |
T10080 |
cc |
and,levels |
R6673 |
T10090 |
T10091 |
advmod |
hence,increase |
R6674 |
T10091 |
T10080 |
conj |
increase,levels |
R6675 |
T10092 |
T10091 |
det |
a,increase |
R6676 |
T10093 |
T10091 |
amod |
small,increase |
R6677 |
T10094 |
T10091 |
prep |
in,increase |
R6678 |
T10095 |
T10096 |
npadvmod |
Ca2,permeable |
R6679 |
T10096 |
T10099 |
amod |
permeable,AMPARs |
R6680 |
T10097 |
T10095 |
punct |
+,Ca2 |
R6681 |
T10098 |
T10096 |
punct |
-,permeable |
R6682 |
T10099 |
T10094 |
pobj |
AMPARs,in |
R6683 |
T10100 |
T10078 |
punct |
", ",arise |
R6684 |
T10101 |
T10078 |
prep |
from,arise |
R6685 |
T10102 |
T10103 |
det |
the,allele |
R6686 |
T10103 |
T10101 |
pobj |
allele,from |
R6687 |
T10104 |
T10103 |
amod |
attenuated,allele |
R6688 |
T10105 |
T10106 |
compound |
GluR,Bneo |
R6689 |
T10106 |
T10103 |
compound |
Bneo,allele |
R6690 |
T10107 |
T10106 |
punct |
-,Bneo |
R6691 |
T10108 |
T10109 |
punct |
[,60 |
R6692 |
T10109 |
T10078 |
parataxis |
60,arise |
R6693 |
T10110 |
T10109 |
punct |
],60 |
R6694 |
T10111 |
T10078 |
punct |
", ",arise |
R6695 |
T10112 |
T10078 |
cc |
and,arise |
R6696 |
T10113 |
T10078 |
punct |
", ",arise |
R6697 |
T10114 |
T10115 |
advmod |
moreover,decreased |
R6698 |
T10115 |
T10078 |
conj |
decreased,arise |
R6699 |
T10116 |
T10115 |
punct |
", ",decreased |
R6700 |
T10117 |
T10115 |
mark |
that,decreased |
R6701 |
T10118 |
T10119 |
compound |
GluR,B |
R6702 |
T10119 |
T10121 |
compound |
B,levels |
R6703 |
T10120 |
T10119 |
punct |
-,B |
R6704 |
T10121 |
T10115 |
nsubjpass |
levels,decreased |
R6705 |
T10122 |
T10115 |
auxpass |
are,decreased |
R6706 |
T10123 |
T10115 |
prep |
in,decreased |
R6707 |
T10124 |
T10125 |
det |
these,mice |
R6708 |
T10125 |
T10123 |
pobj |
mice,in |
R6709 |
T10126 |
T10115 |
prep |
due,decreased |
R6710 |
T10127 |
T10126 |
pcomp |
to,due |
R6711 |
T10128 |
T10129 |
det |
the,copy |
R6712 |
T10129 |
T10126 |
pobj |
copy,due |
R6713 |
T10130 |
T10129 |
amod |
single,copy |
R6714 |
T10131 |
T10129 |
prep |
of,copy |
R6715 |
T10132 |
T10133 |
det |
the,allele |
R6716 |
T10133 |
T10131 |
pobj |
allele,of |
R6717 |
T10134 |
T10135 |
nmod |
GluR,B |
R6718 |
T10135 |
T10133 |
nmod |
B,allele |
R6719 |
T10136 |
T10135 |
punct |
-,B |
R6720 |
T10137 |
T10135 |
punct |
+,B |
R6721 |
T10138 |
T10053 |
punct |
.,be |
R6722 |
T10140 |
T10141 |
prep |
In,plays |
R6723 |
T10142 |
T10143 |
advmod |
virtually,models |
R6724 |
T10143 |
T10140 |
pobj |
models,In |
R6725 |
T10144 |
T10143 |
det |
all,models |
R6726 |
T10145 |
T10143 |
prep |
of,models |
R6727 |
T10146 |
T10147 |
det |
the,bulb |
R6728 |
T10147 |
T10145 |
pobj |
bulb,of |
R6729 |
T10148 |
T10147 |
amod |
olfactory,bulb |
R6730 |
T10149 |
T10141 |
punct |
", ",plays |
R6731 |
T10150 |
T10151 |
amod |
lateral,inhibition |
R6732 |
T10151 |
T10141 |
nsubj |
inhibition,plays |
R6733 |
T10152 |
T10150 |
punct |
(,lateral |
R6734 |
T10153 |
T10150 |
cc |
and,lateral |
R6735 |
T10154 |
T10155 |
punct |
", ",in |
R6736 |
T10155 |
T10156 |
parataxis |
in,recurrent |
R6737 |
T10156 |
T10150 |
conj |
recurrent,lateral |
R6738 |
T10157 |
T10158 |
amod |
fewer,models |
R6739 |
T10158 |
T10155 |
pobj |
models,in |
R6740 |
T10159 |
T10155 |
punct |
", ",in |
R6741 |
T10160 |
T10156 |
advmod |
also,recurrent |
R6742 |
T10161 |
T10151 |
punct |
),inhibition |
R6743 |
T10162 |
T10163 |
det |
a,role |
R6744 |
T10163 |
T10141 |
dobj |
role,plays |
R6745 |
T10164 |
T10163 |
amod |
dominant,role |
R6746 |
T10165 |
T10141 |
punct |
", ",plays |
R6747 |
T10166 |
T10167 |
preconj |
either,in |
R6748 |
T10167 |
T10141 |
prep |
in,plays |
R6749 |
T10168 |
T10167 |
pcomp |
establishing,in |
R6750 |
T10169 |
T10170 |
amod |
spatiotemporal,dynamics |
R6751 |
T10170 |
T10168 |
dobj |
dynamics,establishing |
R6752 |
T10171 |
T10172 |
punct |
[,66 |
R6753 |
T10172 |
T10168 |
parataxis |
66,establishing |
R6754 |
T10173 |
T10172 |
dep |
32,66 |
R6755 |
T10174 |
T10172 |
punct |
",",66 |
R6756 |
T10175 |
T10176 |
punct |
–,69 |
R6757 |
T10176 |
T10172 |
prep |
69,66 |
R6758 |
T10177 |
T10172 |
punct |
],66 |
R6759 |
T10178 |
T10167 |
punct |
", ",in |
R6760 |
T10179 |
T10167 |
cc |
or,in |
R6761 |
T10180 |
T10167 |
conj |
in,in |
R6762 |
T10181 |
T10182 |
advmod |
directly,enhancing |
R6763 |
T10182 |
T10180 |
pcomp |
enhancing,in |
R6764 |
T10183 |
T10182 |
dobj |
contrast,enhancing |
R6765 |
T10184 |
T10182 |
cc |
and,enhancing |
R6766 |
T10185 |
T10186 |
advmod |
therefore,simplifying |
R6767 |
T10186 |
T10182 |
conj |
simplifying,enhancing |
R6768 |
T10187 |
T10186 |
dobj |
discrimination,simplifying |
R6769 |
T10188 |
T10187 |
cc |
and,discrimination |
R6770 |
T10189 |
T10187 |
conj |
learning,discrimination |
R6771 |
T10190 |
T10187 |
prep |
of,discrimination |
R6772 |
T10191 |
T10192 |
amod |
similar,odorants |
R6773 |
T10192 |
T10190 |
pobj |
odorants,of |
R6774 |
T10193 |
T10194 |
punct |
[,36 |
R6775 |
T10194 |
T10186 |
parataxis |
36,simplifying |
R6776 |
T10195 |
T10194 |
nummod |
24,36 |
R6777 |
T10196 |
T10194 |
punct |
",",36 |
R6778 |
T10197 |
T10194 |
nummod |
28,36 |
R6779 |
T10198 |
T10194 |
punct |
",",36 |
R6780 |
T10199 |
T10194 |
nummod |
29,36 |
R6781 |
T10200 |
T10194 |
punct |
",",36 |
R6782 |
T10201 |
T10194 |
punct |
],36 |
R6783 |
T10202 |
T10141 |
punct |
.,plays |
R6784 |
T10204 |
T10205 |
amod |
Increased,inhibition |
R6785 |
T10205 |
T10206 |
nsubj |
inhibition,improve |
R6786 |
T10207 |
T10206 |
aux |
will,improve |
R6787 |
T10208 |
T10206 |
advmod |
thus,improve |
R6788 |
T10209 |
T10206 |
prep |
in,improve |
R6789 |
T10210 |
T10209 |
amod |
general,in |
R6790 |
T10211 |
T10206 |
dobj |
discriminability,improve |
R6791 |
T10212 |
T10206 |
punct |
", ",improve |
R6792 |
T10213 |
T10206 |
advcl |
consistent,improve |
R6793 |
T10214 |
T10213 |
prep |
with,consistent |
R6794 |
T10215 |
T10216 |
det |
the,improvements |
R6795 |
T10216 |
T10214 |
pobj |
improvements,with |
R6796 |
T10217 |
T10216 |
amod |
behavioral,improvements |
R6797 |
T10218 |
T10216 |
acl |
observed,improvements |
R6798 |
T10219 |
T10218 |
prep |
with,observed |
R6799 |
T10220 |
T10221 |
nmod |
GluR,Q |
R6800 |
T10221 |
T10225 |
nmod |
Q,expression |
R6801 |
T10222 |
T10221 |
punct |
-,Q |
R6802 |
T10223 |
T10221 |
nmod |
B,Q |
R6803 |
T10224 |
T10221 |
punct |
(,Q |
R6804 |
T10225 |
T10219 |
pobj |
expression,with |
R6805 |
T10226 |
T10221 |
punct |
),Q |
R6806 |
T10227 |
T10225 |
punct |
", ",expression |
R6807 |
T10228 |
T10229 |
det |
the,knockout |
R6808 |
T10229 |
T10225 |
conj |
knockout,expression |
R6809 |
T10230 |
T10231 |
compound |
GluR,B |
R6810 |
T10231 |
T10229 |
compound |
B,knockout |
R6811 |
T10232 |
T10231 |
punct |
-,B |
R6812 |
T10233 |
T10229 |
punct |
", ",knockout |
R6813 |
T10234 |
T10229 |
cc |
and,knockout |
R6814 |
T10235 |
T10236 |
det |
the,mice |
R6815 |
T10236 |
T10229 |
conj |
mice,knockout |
R6816 |
T10237 |
T10236 |
punct |
“,mice |
R6817 |
T10238 |
T10236 |
nmod |
rescue,mice |
R6818 |
T10239 |
T10236 |
punct |
”,mice |
R6819 |
T10240 |
T10206 |
punct |
.,improve |
R6820 |
T10242 |
T10243 |
det |
A,test |
R6821 |
T10243 |
T10245 |
nsubj |
test,require |
R6822 |
T10244 |
T10243 |
amod |
direct,test |
R6823 |
T10246 |
T10243 |
prep |
of,test |
R6824 |
T10247 |
T10248 |
det |
this,link |
R6825 |
T10248 |
T10246 |
pobj |
link,of |
R6826 |
T10249 |
T10245 |
aux |
would,require |
R6827 |
T10250 |
T10251 |
det |
the,measurement |
R6828 |
T10251 |
T10245 |
dobj |
measurement,require |
R6829 |
T10252 |
T10251 |
amod |
quantitative,measurement |
R6830 |
T10253 |
T10251 |
prep |
of,measurement |
R6831 |
T10254 |
T10253 |
pobj |
inhibition,of |
R6832 |
T10255 |
T10254 |
prep |
in,inhibition |
R6833 |
T10256 |
T10257 |
det |
the,preparation |
R6834 |
T10257 |
T10255 |
pobj |
preparation,in |
R6835 |
T10258 |
T10257 |
amod |
intact,preparation |
R6836 |
T10259 |
T10251 |
punct |
", ",measurement |
R6837 |
T10260 |
T10261 |
det |
a,task |
R6838 |
T10261 |
T10251 |
appos |
task,measurement |
R6839 |
T10262 |
T10263 |
dep |
that,be |
R6840 |
T10263 |
T10261 |
relcl |
be,task |
R6841 |
T10264 |
T10263 |
aux |
might,be |
R6842 |
T10265 |
T10263 |
acomp |
feasible,be |
R6843 |
T10266 |
T10265 |
prep |
with,feasible |
R6844 |
T10267 |
T10268 |
advmod |
further,improved |
R6845 |
T10268 |
T10269 |
amod |
improved,techniques |
R6846 |
T10269 |
T10266 |
pobj |
techniques,with |
R6847 |
T10270 |
T10271 |
advmod |
in,vivo |
R6848 |
T10271 |
T10269 |
amod |
vivo,techniques |
R6849 |
T10272 |
T10269 |
amod |
electrophysiological,techniques |
R6850 |
T10273 |
T10269 |
punct |
", ",techniques |
R6851 |
T10274 |
T10275 |
amod |
such,as |
R6852 |
T10275 |
T10269 |
prep |
as,techniques |
R6853 |
T10276 |
T10277 |
amod |
targeted,recordings |
R6854 |
T10277 |
T10275 |
pobj |
recordings,as |
R6855 |
T10278 |
T10279 |
punct |
[,71 |
R6856 |
T10279 |
T10269 |
parataxis |
71,techniques |
R6857 |
T10280 |
T10279 |
nummod |
70,71 |
R6858 |
T10281 |
T10279 |
punct |
",",71 |
R6859 |
T10282 |
T10279 |
punct |
],71 |
R6860 |
T10283 |
T10269 |
cc |
or,techniques |
R6861 |
T10284 |
T10285 |
amod |
simultaneous,measurements |
R6862 |
T10285 |
T10269 |
conj |
measurements,techniques |
R6863 |
T10286 |
T10287 |
advmod |
pre,postsynaptic |
R6864 |
T10287 |
T10285 |
amod |
postsynaptic,measurements |
R6865 |
T10288 |
T10287 |
punct |
-,postsynaptic |
R6866 |
T10289 |
T10287 |
cc |
and,postsynaptic |
R6867 |
T10290 |
T10285 |
amod |
intracellular,measurements |
R6868 |
T10291 |
T10245 |
punct |
.,require |