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PMC:1253828 / 35289-35979 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T11087 0-3 DT denotes The
T11088 12-17 NN denotes study
T11089 4-11 JJ denotes present
T11090 18-26 VBZ denotes confirms
T11091 27-30 CC denotes and
T11092 31-38 VBZ denotes extends
T11093 39-42 DT denotes the
T11094 43-47 NN denotes role
T11095 48-50 IN denotes of
T11096 51-54 NN denotes MTF
T11097 54-55 HYPH denotes -
T11098 55-56 CD denotes 1
T11099 57-59 IN denotes as
T11100 60-62 DT denotes an
T11101 89-98 NN denotes regulator
T11102 63-72 JJ denotes important
T11103 73-79 NN denotes stress
T11104 80-88 NN denotes response
T11105 98-99 . denotes .
T11106 99-336 sentence denotes We have identified and preliminarily characterized four target genes of MTF-1 in the adult mouse liver: in the case of Sepw1, MTF-1 is required to maintain basal expression, supporting a role of mouse MTF-1 in oxidative stress response.
T11107 100-102 PRP denotes We
T11108 108-118 VBN denotes identified
T11109 103-107 VBP denotes have
T11110 235-243 VBN denotes required
T11111 119-122 CC denotes and
T11112 123-136 RB denotes preliminarily
T11113 137-150 VBN denotes characterized
T11114 151-155 CD denotes four
T11115 163-168 NNS denotes genes
T11116 156-162 NN denotes target
T11117 169-171 IN denotes of
T11118 172-175 NN denotes MTF
T11119 175-176 HYPH denotes -
T11120 176-177 CD denotes 1
T11121 178-180 IN denotes in
T11122 181-184 DT denotes the
T11123 197-202 NN denotes liver
T11124 185-190 JJ denotes adult
T11125 191-196 NN denotes mouse
T11126 202-204 : denotes :
T11127 204-206 IN denotes in
T11128 207-210 DT denotes the
T11129 211-215 NN denotes case
T11130 216-218 IN denotes of
T11131 219-224 NN denotes Sepw1
T11132 224-226 , denotes ,
T11133 226-229 NN denotes MTF
T11134 229-230 HYPH denotes -
T11135 230-231 CD denotes 1
T11136 232-234 VBZ denotes is
T11137 244-246 TO denotes to
T11138 247-255 VB denotes maintain
T11139 256-261 JJ denotes basal
T11140 262-272 NN denotes expression
T11141 272-274 , denotes ,
T11142 274-284 VBG denotes supporting
T11143 285-286 DT denotes a
T11144 287-291 NN denotes role
T11145 292-294 IN denotes of
T11146 295-300 NN denotes mouse
T11147 301-304 NN denotes MTF
T11148 304-305 HYPH denotes -
T11149 305-306 CD denotes 1
T11150 307-309 IN denotes in
T11151 310-319 JJ denotes oxidative
T11152 327-335 NN denotes response
T11153 320-326 NN denotes stress
T11154 335-336 . denotes .
T11155 336-421 sentence denotes In addition, MTF-1 contributes to the cadmium-induced expression of Ndrg1 and Csrp1.
T11156 337-339 IN denotes In
T11157 356-367 VBZ denotes contributes
T11158 340-348 NN denotes addition
T11159 348-350 , denotes ,
T11160 350-353 NN denotes MTF
T11161 353-354 HYPH denotes -
T11162 354-355 CD denotes 1
T11163 368-370 IN denotes to
T11164 371-374 DT denotes the
T11165 391-401 NN denotes expression
T11166 375-382 NN denotes cadmium
T11167 383-390 VBN denotes induced
T11168 382-383 HYPH denotes -
T11169 402-404 IN denotes of
T11170 405-410 NN denotes Ndrg1
T11171 411-414 CC denotes and
T11172 415-420 NN denotes Csrp1
T11173 420-421 . denotes .
T11174 421-577 sentence denotes Furthermore, MTF-1 helps to repress the basal expression of Slc39a10, in contrast to its role as transcriptional activator for genes like Mt1, Mt2 or Znt1.
T11175 422-433 RB denotes Furthermore
T11176 441-446 VBZ denotes helps
T11177 433-435 , denotes ,
T11178 435-438 NN denotes MTF
T11179 438-439 HYPH denotes -
T11180 439-440 CD denotes 1
T11181 447-449 TO denotes to
T11182 450-457 VB denotes repress
T11183 458-461 DT denotes the
T11184 468-478 NN denotes expression
T11185 462-467 JJ denotes basal
T11186 479-481 IN denotes of
T11187 482-490 NN denotes Slc39a10
T11188 490-492 , denotes ,
T11189 492-494 IN denotes in
T11190 495-503 NN denotes contrast
T11191 504-506 IN denotes to
T11192 507-510 PRP$ denotes its
T11193 511-515 NN denotes role
T11194 516-518 IN denotes as
T11195 519-534 JJ denotes transcriptional
T11196 535-544 NN denotes activator
T11197 545-548 IN denotes for
T11198 549-554 NNS denotes genes
T11199 555-559 IN denotes like
T11200 560-563 NN denotes Mt1
T11201 563-565 , denotes ,
T11202 565-568 NN denotes Mt2
T11203 569-571 CC denotes or
T11204 572-576 NN denotes Znt1
T11205 576-577 . denotes .
T11206 577-690 sentence denotes Thus the same transcription factor apparently serves as an activator or repressor, depending on the target gene.
T11207 578-582 RB denotes Thus
T11208 624-630 VBZ denotes serves
T11209 583-586 DT denotes the
T11210 606-612 NN denotes factor
T11211 587-591 JJ denotes same
T11212 592-605 NN denotes transcription
T11213 613-623 RB denotes apparently
T11214 631-633 IN denotes as
T11215 634-636 DT denotes an
T11216 637-646 NN denotes activator
T11217 647-649 CC denotes or
T11218 650-659 NN denotes repressor
T11219 659-661 , denotes ,
T11220 661-670 VBG denotes depending
T11221 671-673 IN denotes on
T11222 674-677 DT denotes the
T11223 685-689 NN denotes gene
T11224 678-684 NN denotes target
T11225 689-690 . denotes .
R6723 T11087 T11088 det The,study
R6724 T11088 T11090 nsubj study,confirms
R6725 T11089 T11088 amod present,study
R6727 T11091 T11090 cc and,confirms
R6728 T11092 T11090 conj extends,confirms
R6730 T11093 T11094 det the,role
R6731 T11094 T11092 dobj role,extends
R6732 T11095 T11094 prep of,role
R6734 T11096 T11095 pobj MTF,of
R6735 T11097 T11096 punct -,MTF
R6736 T11098 T11096 nummod 1,MTF
R6738 T11099 T11094 prep as,role
R6739 T11100 T11101 det an,regulator
R6741 T11101 T11099 pobj regulator,as
R6742 T11102 T11101 amod important,regulator
R6743 T11103 T11104 compound stress,response
R6745 T11104 T11101 compound response,regulator
R6746 T11105 T11090 punct .,confirms
R6747 T11107 T11108 nsubj We,identified
R6748 T11108 T11110 ccomp identified,required
R6749 T11109 T11108 aux have,identified
R6751 T11111 T11108 cc and,identified
R6752 T11112 T11113 advmod preliminarily,characterized
R6754 T11113 T11108 conj characterized,identified
R6755 T11114 T11115 nummod four,genes
R6756 T11115 T11113 dobj genes,characterized
R6758 T11116 T11115 compound target,genes
R6759 T11117 T11115 prep of,genes
R6761 T11118 T11117 pobj MTF,of
R6762 T11119 T11118 punct -,MTF
R6763 T11120 T11118 nummod 1,MTF
R6765 T11121 T11115 prep in,genes
R6766 T11122 T11123 det the,liver
R6767 T11123 T11121 pobj liver,in
R6768 T11124 T11123 amod adult,liver
R6770 T11125 T11123 compound mouse,liver
R6771 T11126 T11110 punct : ,required
R6773 T11127 T11110 prep in,required
R6774 T11128 T11129 det the,case
R6775 T11129 T11127 pobj case,in
R6776 T11130 T11129 prep of,case
R6778 T11131 T11130 pobj Sepw1,of
R6779 T11132 T11110 punct ", ",required
R6780 T11133 T11110 nsubjpass MTF,required
R6782 T11134 T11133 punct -,MTF
R6783 T11135 T11133 nummod 1,MTF
R6785 T11136 T11110 auxpass is,required
R6786 T11137 T11138 aux to,maintain
R6787 T11138 T11110 advcl maintain,required
R6789 T11139 T11140 amod basal,expression
R6790 T11140 T11138 dobj expression,maintain
R6791 T11141 T11110 punct ", ",required
R6793 T11142 T11110 advcl supporting,required
R6794 T11143 T11144 det a,role
R6795 T11144 T11142 dobj role,supporting
R6797 T11145 T11144 prep of,role
R6798 T11146 T11147 compound mouse,MTF
R6799 T11147 T11145 pobj MTF,of
R6800 T11148 T11147 punct -,MTF
R6801 T11149 T11147 nummod 1,MTF
R6802 T11150 T11144 prep in,role
R6804 T11151 T11152 amod oxidative,response
R6806 T11152 T11150 pobj response,in
R6807 T11153 T11152 compound stress,response
R6809 T11154 T11110 punct .,required
R6810 T11156 T11157 prep In,contributes
R6816 T11158 T11156 pobj addition,In
R6817 T11159 T11157 punct ", ",contributes
R6818 T11160 T11157 nsubj MTF,contributes
R6820 T11161 T11160 punct -,MTF
R6821 T11162 T11160 nummod 1,MTF
R6823 T11163 T11157 prep to,contributes
R6824 T11164 T11165 det the,expression
R6827 T11166 T11167 npadvmod cadmium,induced
R6828 T11167 T11165 amod induced,expression
R6829 T11168 T11167 punct -,induced
R6831 T11169 T11165 prep of,expression
R6832 T11170 T11169 pobj Ndrg1,of
R6833 T11171 T11170 cc and,Ndrg1
R6834 T11172 T11170 conj Csrp1,Ndrg1
R6836 T11173 T11157 punct .,contributes
R6837 T11175 T11176 advmod Furthermore,helps
R6839 T11177 T11176 punct ", ",helps
R6841 T11178 T11176 nsubj MTF,helps
R6842 T11179 T11178 punct -,MTF
R6843 T11180 T11178 nummod 1,MTF
R6845 T11181 T11182 aux to,repress
R6846 T11182 T11176 xcomp repress,helps
R6847 T11183 T11184 det the,expression
R6849 T11184 T11182 dobj expression,repress
R6850 T11185 T11184 amod basal,expression
R6851 T11186 T11184 prep of,expression
R6852 T11187 T11186 pobj Slc39a10,of
R6853 T11188 T11182 punct ", ",repress
R6854 T11189 T11182 prep in,repress
R6856 T11190 T11189 pobj contrast,in
R6857 T11191 T11190 prep to,contrast
R6858 T11192 T11193 poss its,role
R6859 T11193 T11191 pobj role,to
R6861 T11194 T11193 prep as,role
R6862 T11195 T11196 amod transcriptional,activator
R6864 T11196 T11194 pobj activator,as
R6865 T11197 T11196 prep for,activator
R6866 T11198 T11197 pobj genes,for
R6868 T11199 T11198 prep like,genes
R6869 T11200 T11199 pobj Mt1,like
R6870 T11201 T11200 punct ", ",Mt1
R6872 T11202 T11200 conj Mt2,Mt1
R6873 T11203 T11202 cc or,Mt2
R6874 T11204 T11202 conj Znt1,Mt2
R6876 T11205 T11176 punct .,helps
R6878 T11207 T11208 advmod Thus,serves
R6879 T11209 T11210 det the,factor
R6881 T11210 T11208 nsubj factor,serves
R6882 T11211 T11210 amod same,factor
R6884 T11212 T11210 compound transcription,factor
R6885 T11213 T11208 advmod apparently,serves
R6886 T11214 T11208 prep as,serves
R6887 T11215 T11216 det an,activator
R6889 T11216 T11214 pobj activator,as
R6890 T11217 T11216 cc or,activator
R6891 T11218 T11216 conj repressor,activator
R6893 T11219 T11208 punct ", ",serves
R6894 T11220 T11208 prep depending,serves
R6895 T11221 T11220 prep on,depending
R6897 T11222 T11223 det the,gene
R6898 T11223 T11221 pobj gene,on
R6899 T11224 T11223 compound target,gene
R6901 T11225 T11208 punct .,serves
R6825 T11165 T11163 pobj expression,to

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T9254 51-56 PR:000010717 denotes MTF-1
T9255 163-168 SO:0000704 denotes genes
T9256 172-177 PR:000010717 denotes MTF-1
T9257 185-190 UBERON:0007023 denotes adult
T9258 191-196 NCBITaxon:10088 denotes mouse
T9259 197-202 UBERON:0002107 denotes liver
T9260 219-224 PR:000014662 denotes Sepw1
T9261 226-231 PR:000010717 denotes MTF-1
T9262 262-272 GO:0010467 denotes expression
T9263 295-300 NCBITaxon:10088 denotes mouse
T9264 301-306 PR:000010717 denotes MTF-1
T9265 310-319 MOP:0000568 denotes oxidative
T9266 350-355 PR:000010717 denotes MTF-1
T9267 391-401 GO:0010467 denotes expression
T9268 405-410 PR:000011059 denotes Ndrg1
T9269 415-420 PR:000005958 denotes Csrp1
T9270 435-440 PR:000010717 denotes MTF-1
T9271 468-478 GO:0010467 denotes expression
T9272 482-490 PR:000015124 denotes Slc39a10
T9273 549-554 SO:0000704 denotes genes
T9274 560-563 PR:000010925 denotes Mt1
T9275 565-568 PR:000010704 denotes Mt2
T9276 572-576 PR:000015073 denotes Znt1
T9277 685-689 SO:0000704 denotes gene

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T9668 51-56 PR_EXT:000010717 denotes MTF-1
T9669 80-88 GO_EXT:reaction_or_response denotes response
T9670 89-98 GO_EXT:regulator denotes regulator
T9671 163-168 SO_EXT:0000704 denotes genes
T9672 172-177 PR_EXT:000010717 denotes MTF-1
T9673 185-190 UBERON:0007023 denotes adult
T9674 191-196 NCBITaxon:10088 denotes mouse
T9675 197-202 UBERON:0002107 denotes liver
T9676 219-224 PR_EXT:000014662 denotes Sepw1
T9677 226-231 PR_EXT:000010717 denotes MTF-1
T9678 262-272 GO:0010467 denotes expression
T9679 295-300 NCBITaxon:10088 denotes mouse
T9680 301-306 PR_EXT:000010717 denotes MTF-1
T9681 310-319 MOP:0000568 denotes oxidative
T9682 327-335 GO_EXT:reaction_or_response denotes response
T9683 350-355 PR_EXT:000010717 denotes MTF-1
T9684 375-382 CHEBI_EXT:cadmium denotes cadmium
T9685 391-401 GO:0010467 denotes expression
T9686 405-410 PR_EXT:000011059 denotes Ndrg1
T9687 415-420 PR_EXT:000005958 denotes Csrp1
T9688 435-440 PR_EXT:000010717 denotes MTF-1
T9689 468-478 GO:0010467 denotes expression
T9690 482-490 PR_EXT:000015124 denotes Slc39a10
T9691 519-534 GO_EXT:transcription denotes transcriptional
T9692 549-554 SO_EXT:0000704 denotes genes
T9693 560-563 PR_EXT:000010925 denotes Mt1
T9694 565-568 PR_EXT:000010704 denotes Mt2
T9695 572-576 PR_EXT:000015073 denotes Znt1
T9696 592-605 GO_EXT:transcription denotes transcription
T9697 592-612 GO_EXT:transcription_factor denotes transcription factor
T9698 685-689 SO_EXT:0000704 denotes gene