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PMC:1253828 / 27362-28193 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T8416 0-2 TO denotes To
T8417 3-10 VB denotes analyze
T8418 146-153 VBN denotes treated
T8419 11-14 DT denotes the
T8420 15-19 NN denotes role
T8421 20-22 IN denotes of
T8422 23-26 DT denotes the
T8423 39-45 NN denotes system
T8424 27-38 NN denotes glutathione
T8425 46-48 IN denotes in
T8426 49-52 DT denotes the
T8427 70-78 NN denotes response
T8428 53-61 JJ denotes cellular
T8429 62-69 NN denotes cadmium
T8430 78-80 , denotes ,
T8431 80-85 NN denotes mouse
T8432 96-107 NNS denotes fibroblasts
T8433 86-95 JJ denotes embryonic
T8434 108-112 IN denotes with
T8435 113-116 CC denotes and
T8436 117-124 IN denotes without
T8437 125-135 JJ denotes functional
T8438 136-140 NN denotes Mtf1
T8439 141-145 VBD denotes were
T8440 154-158 IN denotes with
T8441 159-166 NN denotes cadmium
T8442 167-169 IN denotes in
T8443 170-181 NN denotes combination
T8444 182-186 IN denotes with
T8445 187-190 NN denotes BSO
T8446 190-192 , denotes ,
T8447 192-193 DT denotes a
T8448 203-212 NN denotes inhibitor
T8449 194-202 JJ denotes specific
T8450 213-215 IN denotes of
T8451 216-225 NN denotes glutamate
T8452 226-234 NN denotes cysteine
T8453 225-226 HYPH denotes -
T8454 235-241 NN denotes ligase
T8455 242-243 -LRB- denotes (
T8456 243-245 CD denotes 31
T8457 245-246 -RRB- denotes )
T8458 246-248 , denotes ,
T8459 248-251 CC denotes and
T8460 252-256 NN denotes cell
T8461 257-266 NN denotes viability
T8462 271-279 VBN denotes assessed
T8463 267-270 VBD denotes was
T8464 280-282 IN denotes by
T8465 283-284 DT denotes a
T8466 298-303 NN denotes assay
T8467 285-297 JJ denotes colorimetric
T8468 304-309 VBN denotes based
T8469 310-312 IN denotes on
T8470 313-316 DT denotes the
T8471 329-333 NN denotes salt
T8472 317-328 NN denotes tetrazolium
T8473 334-337 NN denotes MTT
T8474 338-339 -LRB- denotes (
T8475 339-345 NN denotes Figure
T8476 346-347 CD denotes 6
T8477 347-348 -RRB- denotes )
T8478 348-349 . denotes .
T8479 349-458 sentence denotes Increasing concentrations of BSO or cadmium alone were to some extent cytotoxic for the examined cell lines.
T8480 350-360 VBG denotes Increasing
T8481 361-375 NNS denotes concentrations
T8482 400-404 VBD denotes were
T8483 376-378 IN denotes of
T8484 379-382 NN denotes BSO
T8485 383-385 CC denotes or
T8486 386-393 NN denotes cadmium
T8487 394-399 RB denotes alone
T8488 405-407 IN denotes to
T8489 408-412 DT denotes some
T8490 413-419 NN denotes extent
T8491 420-429 JJ denotes cytotoxic
T8492 430-433 IN denotes for
T8493 434-437 DT denotes the
T8494 452-457 NNS denotes lines
T8495 438-446 VBN denotes examined
T8496 447-451 NN denotes cell
T8497 457-458 . denotes .
T8498 458-694 sentence denotes Treatment with both BSO and cadmium resulted in an enhanced lethality particularly for the cells without functional Mtf1, indicating that a depletion of glutathione together with a lack of Mtf1 impair an efficient anti-cadmium defense.
T8499 459-468 NN denotes Treatment
T8500 495-503 VBD denotes resulted
T8501 469-473 IN denotes with
T8502 474-478 CC denotes both
T8503 479-482 NN denotes BSO
T8504 483-486 CC denotes and
T8505 487-494 NN denotes cadmium
T8506 504-506 IN denotes in
T8507 507-509 DT denotes an
T8508 519-528 NN denotes lethality
T8509 510-518 VBN denotes enhanced
T8510 529-541 RB denotes particularly
T8511 542-545 IN denotes for
T8512 546-549 DT denotes the
T8513 550-555 NNS denotes cells
T8514 556-563 IN denotes without
T8515 564-574 JJ denotes functional
T8516 575-579 NN denotes Mtf1
T8517 579-581 , denotes ,
T8518 581-591 VBG denotes indicating
T8519 592-596 IN denotes that
T8520 653-659 VBP denotes impair
T8521 597-598 DT denotes a
T8522 599-608 NN denotes depletion
T8523 609-611 IN denotes of
T8524 612-623 NN denotes glutathione
T8525 624-632 RB denotes together
T8526 633-637 IN denotes with
T8527 638-639 DT denotes a
T8528 640-644 NN denotes lack
T8529 645-647 IN denotes of
T8530 648-652 NN denotes Mtf1
T8531 660-662 DT denotes an
T8532 686-693 NN denotes defense
T8533 663-672 JJ denotes efficient
T8534 673-685 JJ denotes anti-cadmium
T8535 693-694 . denotes .
T8536 694-831 sentence denotes Thus, adequate glutathione supply as well as MTF-1 and its target genes are essential for the survival of the cell under cadmium stress.
T8537 695-699 RB denotes Thus
T8538 767-770 VBP denotes are
T8539 699-701 , denotes ,
T8540 701-709 JJ denotes adequate
T8541 722-728 NN denotes supply
T8542 710-721 NN denotes glutathione
T8543 729-731 RB denotes as
T8544 737-739 IN denotes as
T8545 732-736 RB denotes well
T8546 740-743 NN denotes MTF
T8547 743-744 HYPH denotes -
T8548 744-745 CD denotes 1
T8549 746-749 CC denotes and
T8550 750-753 PRP$ denotes its
T8551 761-766 NNS denotes genes
T8552 754-760 NN denotes target
T8553 771-780 JJ denotes essential
T8554 781-784 IN denotes for
T8555 785-788 DT denotes the
T8556 789-797 NN denotes survival
T8557 798-800 IN denotes of
T8558 801-804 DT denotes the
T8559 805-809 NN denotes cell
T8560 810-815 IN denotes under
T8561 816-823 NN denotes cadmium
T8562 824-830 NN denotes stress
T8563 830-831 . denotes .
R5324 T8416 T8417 aux To,analyze
R5325 T8417 T8418 advcl analyze,treated
R5326 T8419 T8420 det the,role
R5327 T8420 T8417 dobj role,analyze
R5328 T8421 T8420 prep of,role
R5329 T8422 T8423 det the,system
R5330 T8423 T8421 pobj system,of
R5331 T8424 T8423 compound glutathione,system
R5332 T8425 T8420 prep in,role
R5333 T8426 T8427 det the,response
R5334 T8427 T8425 pobj response,in
R5335 T8428 T8427 amod cellular,response
R5336 T8429 T8427 compound cadmium,response
R5337 T8430 T8418 punct ", ",treated
R5338 T8431 T8432 nmod mouse,fibroblasts
R5339 T8432 T8418 nsubjpass fibroblasts,treated
R5340 T8433 T8432 amod embryonic,fibroblasts
R5341 T8434 T8432 prep with,fibroblasts
R5342 T8435 T8434 cc and,with
R5343 T8436 T8434 conj without,with
R5344 T8437 T8438 amod functional,Mtf1
R5345 T8438 T8436 pobj Mtf1,without
R5346 T8439 T8418 auxpass were,treated
R5347 T8440 T8418 prep with,treated
R5348 T8441 T8440 pobj cadmium,with
R5349 T8442 T8418 prep in,treated
R5350 T8443 T8442 pobj combination,in
R5351 T8444 T8443 prep with,combination
R5352 T8445 T8444 pobj BSO,with
R5353 T8446 T8445 punct ", ",BSO
R5354 T8447 T8448 det a,inhibitor
R5355 T8448 T8445 appos inhibitor,BSO
R5356 T8449 T8448 amod specific,inhibitor
R5357 T8450 T8448 prep of,inhibitor
R5358 T8451 T8452 compound glutamate,cysteine
R5359 T8452 T8454 compound cysteine,ligase
R5360 T8453 T8452 punct -,cysteine
R5361 T8454 T8450 pobj ligase,of
R5362 T8455 T8456 punct (,31
R5363 T8456 T8454 parataxis 31,ligase
R5364 T8457 T8456 punct ),31
R5365 T8458 T8418 punct ", ",treated
R5366 T8459 T8418 cc and,treated
R5367 T8460 T8461 compound cell,viability
R5368 T8461 T8462 nsubjpass viability,assessed
R5369 T8462 T8418 conj assessed,treated
R5370 T8463 T8462 auxpass was,assessed
R5371 T8464 T8462 agent by,assessed
R5372 T8465 T8466 det a,assay
R5373 T8466 T8464 pobj assay,by
R5374 T8467 T8466 amod colorimetric,assay
R5375 T8468 T8466 prep based,assay
R5376 T8469 T8468 prep on,based
R5377 T8470 T8471 det the,salt
R5378 T8471 T8469 pobj salt,on
R5379 T8472 T8471 compound tetrazolium,salt
R5380 T8473 T8471 appos MTT,salt
R5381 T8474 T8475 punct (,Figure
R5382 T8475 T8462 parataxis Figure,assessed
R5383 T8476 T8475 nummod 6,Figure
R5384 T8477 T8475 punct ),Figure
R5385 T8478 T8462 punct .,assessed
R5386 T8480 T8481 amod Increasing,concentrations
R5387 T8481 T8482 nsubj concentrations,were
R5388 T8483 T8481 prep of,concentrations
R5389 T8484 T8483 pobj BSO,of
R5390 T8485 T8484 cc or,BSO
R5391 T8486 T8484 conj cadmium,BSO
R5392 T8487 T8484 advmod alone,BSO
R5393 T8488 T8482 prep to,were
R5394 T8489 T8490 det some,extent
R5395 T8490 T8488 pobj extent,to
R5396 T8491 T8482 acomp cytotoxic,were
R5397 T8492 T8491 prep for,cytotoxic
R5398 T8493 T8494 det the,lines
R5399 T8494 T8492 pobj lines,for
R5400 T8495 T8494 amod examined,lines
R5401 T8496 T8494 compound cell,lines
R5402 T8497 T8482 punct .,were
R5403 T8499 T8500 nsubj Treatment,resulted
R5404 T8501 T8499 prep with,Treatment
R5405 T8502 T8503 preconj both,BSO
R5406 T8503 T8501 pobj BSO,with
R5407 T8504 T8503 cc and,BSO
R5408 T8505 T8503 conj cadmium,BSO
R5409 T8506 T8500 prep in,resulted
R5410 T8507 T8508 det an,lethality
R5411 T8508 T8506 pobj lethality,in
R5412 T8509 T8508 amod enhanced,lethality
R5413 T8510 T8511 advmod particularly,for
R5414 T8511 T8500 prep for,resulted
R5415 T8512 T8513 det the,cells
R5416 T8513 T8511 pobj cells,for
R5417 T8514 T8513 prep without,cells
R5418 T8515 T8516 amod functional,Mtf1
R5419 T8516 T8514 pobj Mtf1,without
R5420 T8517 T8500 punct ", ",resulted
R5421 T8518 T8500 advcl indicating,resulted
R5422 T8519 T8520 mark that,impair
R5423 T8520 T8518 ccomp impair,indicating
R5424 T8521 T8522 det a,depletion
R5425 T8522 T8520 nsubj depletion,impair
R5426 T8523 T8522 prep of,depletion
R5427 T8524 T8523 pobj glutathione,of
R5428 T8525 T8522 advmod together,depletion
R5429 T8526 T8525 prep with,together
R5430 T8527 T8528 det a,lack
R5431 T8528 T8526 pobj lack,with
R5432 T8529 T8528 prep of,lack
R5433 T8530 T8529 pobj Mtf1,of
R5434 T8531 T8532 det an,defense
R5435 T8532 T8520 dobj defense,impair
R5436 T8533 T8532 amod efficient,defense
R5437 T8534 T8532 amod anti-cadmium,defense
R5438 T8535 T8500 punct .,resulted
R5439 T8537 T8538 advmod Thus,are
R5440 T8539 T8538 punct ", ",are
R5441 T8540 T8541 amod adequate,supply
R5442 T8541 T8538 nsubj supply,are
R5443 T8542 T8541 compound glutathione,supply
R5444 T8543 T8544 advmod as,as
R5445 T8544 T8541 cc as,supply
R5446 T8545 T8544 advmod well,as
R5447 T8546 T8541 conj MTF,supply
R5448 T8547 T8546 punct -,MTF
R5449 T8548 T8546 nummod 1,MTF
R5450 T8549 T8541 cc and,supply
R5451 T8550 T8551 poss its,genes
R5452 T8551 T8541 conj genes,supply
R5453 T8552 T8551 compound target,genes
R5454 T8553 T8538 acomp essential,are
R5455 T8554 T8553 prep for,essential
R5456 T8555 T8556 det the,survival
R5457 T8556 T8554 pobj survival,for
R5458 T8557 T8556 prep of,survival
R5459 T8558 T8559 det the,cell
R5460 T8559 T8557 pobj cell,of
R5461 T8560 T8556 prep under,survival
R5462 T8561 T8562 compound cadmium,stress
R5463 T8562 T8560 pobj stress,under
R5464 T8563 T8538 punct .,are

2_test

Id Subject Object Predicate Lexical cue
16221973-38242-77403441 243-245 38242 denotes 31

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7936 27-38 CHEBI:16856 denotes glutathione
T7937 53-61 _FRAGMENT denotes cellular
T7938 70-78 GO:0051716 denotes response
T7939 80-85 NCBITaxon:10088 denotes mouse
T7940 86-95 UBERON:0000922 denotes embryonic
T7941 96-107 CL:0000057 denotes fibroblasts
T7942 136-140 PR:000010717 denotes Mtf1
T7943 187-190 CHEBI:28714 denotes BSO
T7944 203-241 CHEBI:75599 denotes inhibitor of glutamate-cysteine ligase
T7945 317-328 CHEBI:78021 denotes tetrazolium
T7946 329-333 CHEBI:24866 denotes salt
T7947 334-337 CHEBI:53233 denotes MTT
T7948 379-382 CHEBI:28714 denotes BSO
T7949 479-482 CHEBI:28714 denotes BSO
T7950 575-579 PR:000010717 denotes Mtf1
T7951 612-623 CHEBI:16856 denotes glutathione
T7952 648-652 PR:000010717 denotes Mtf1
T7953 686-693 GO:0006952 denotes defense
T7954 710-721 CHEBI:16856 denotes glutathione
T7955 740-745 PR:000010717 denotes MTF-1
T7956 761-766 SO:0000704 denotes genes
R5030 T7938 T7937 _lexicallyChainedTo response,cellular

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T8046 27-38 CHEBI:16856 denotes glutathione
T8047 53-61 CL_GO_EXT:cell denotes cellular
T8048 53-61 _FRAGMENT denotes cellular
T8049 70-78 GO:0051716 denotes response
T8050 62-69 CHEBI_EXT:cadmium denotes cadmium
T8051 80-85 NCBITaxon:10088 denotes mouse
T8052 86-95 UBERON:0000922 denotes embryonic
T8053 96-107 CL:0000057 denotes fibroblasts
T8054 136-140 PR_EXT:000010717 denotes Mtf1
T8055 159-166 CHEBI_EXT:cadmium denotes cadmium
T8056 187-190 CHEBI:28714 denotes BSO
T8057 203-215 _FRAGMENT denotes inhibitor of
T8058 235-241 CHEBI_GO_EXT:ligase_inhibitor denotes ligase
T8059 203-241 CHEBI_EXT:75599 denotes inhibitor of glutamate-cysteine ligase
T8060 216-241 GO_EXT:0004357 denotes glutamate-cysteine ligase
T8061 226-234 CHEBI_SO_EXT:cysteine denotes cysteine
T8062 252-256 CL_GO_EXT:cell denotes cell
T8063 317-328 CHEBI:78021 denotes tetrazolium
T8064 329-333 CHEBI:24866 denotes salt
T8065 334-337 CHEBI:53233 denotes MTT
T8066 379-382 CHEBI:28714 denotes BSO
T8067 386-393 CHEBI_EXT:cadmium denotes cadmium
T8068 447-451 CL_GO_EXT:cell denotes cell
T8069 479-482 CHEBI:28714 denotes BSO
T8070 487-494 CHEBI_EXT:cadmium denotes cadmium
T8071 519-528 GO_EXT:fatality_or_lethality denotes lethality
T8072 550-555 CL_GO_EXT:cell denotes cells
T8073 575-579 PR_EXT:000010717 denotes Mtf1
T8074 612-623 CHEBI:16856 denotes glutathione
T8075 648-652 PR_EXT:000010717 denotes Mtf1
T8076 678-685 CHEBI_EXT:cadmium denotes cadmium
T8077 686-693 GO:0006952 denotes defense
T8078 710-721 CHEBI:16856 denotes glutathione
T8079 740-745 PR_EXT:000010717 denotes MTF-1
T8080 761-766 SO_EXT:0000704 denotes genes
T8081 805-809 CL_GO_EXT:cell denotes cell
T8082 816-823 CHEBI_EXT:cadmium denotes cadmium
R5032 T8049 T8048 _lexicallyChainedTo response,cellular
R5033 T8058 T8057 _lexicallyChainedTo ligase,inhibitor of