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PMC:1253828 / 0-508 JSONTXT

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Id Subject Object Predicate Lexical cue
T240 10-18 NNS denotes branches
T241 0-95 sentence denotes Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione
T242 4-9 JJ denotes major
T243 19-21 IN denotes of
T244 22-34 JJ denotes anti-cadmium
T245 35-42 NN denotes defense
T246 43-45 IN denotes in
T247 46-49 DT denotes the
T248 50-55 NN denotes mouse
T249 55-57 : denotes :
T250 57-60 NN denotes MTF
T251 63-79 NNS denotes metallothioneins
T252 60-61 HYPH denotes -
T253 61-62 CD denotes 1
T254 62-63 HYPH denotes /
T255 80-83 CC denotes and
T256 84-95 NN denotes glutathione
T257 95-96 sentence denotes
T258 106-353 sentence denotes Metal-responsive transcription factor 1 (MTF-1) regulates expression of its target genes in response to various stress conditions, notably heavy metal load, via binding to metal response elements (MREs) in the respective enhancer/promoter regions.
T259 106-111 NN denotes Metal
T260 112-122 JJ denotes responsive
T261 111-112 HYPH denotes -
T262 137-143 NN denotes factor
T263 123-136 NN denotes transcription
T264 154-163 VBZ denotes regulates
T265 144-145 CD denotes 1
T266 146-147 -LRB- denotes (
T267 147-150 NN denotes MTF
T268 150-151 HYPH denotes -
T269 151-152 CD denotes 1
T270 152-153 -RRB- denotes )
T271 164-174 NN denotes expression
T272 175-177 IN denotes of
T273 178-181 PRP$ denotes its
T274 189-194 NNS denotes genes
T275 182-188 NN denotes target
T276 195-197 IN denotes in
T277 198-206 NN denotes response
T278 207-209 IN denotes to
T279 210-217 JJ denotes various
T280 225-235 NNS denotes conditions
T281 218-224 NN denotes stress
T282 235-237 , denotes ,
T283 237-244 RB denotes notably
T284 257-261 NN denotes load
T285 245-250 JJ denotes heavy
T286 251-256 NN denotes metal
T287 261-263 , denotes ,
T288 263-266 IN denotes via
T289 267-274 NN denotes binding
T290 275-277 IN denotes to
T291 278-283 NN denotes metal
T292 293-301 NNS denotes elements
T293 284-292 NN denotes response
T294 302-303 -LRB- denotes (
T295 303-307 NNS denotes MREs
T296 307-308 -RRB- denotes )
T297 309-311 IN denotes in
T298 312-315 DT denotes the
T299 345-352 NNS denotes regions
T300 316-326 JJ denotes respective
T301 327-335 NN denotes enhancer
T302 336-344 NN denotes promoter
T303 335-336 HYPH denotes /
T304 352-353 . denotes .
T305 353-425 sentence denotes Furthermore, it serves a vital function in embryonic liver development.
T306 354-365 RB denotes Furthermore
T307 370-376 VBZ denotes serves
T308 365-367 , denotes ,
T309 367-369 PRP denotes it
T310 377-378 DT denotes a
T311 385-393 NN denotes function
T312 379-384 JJ denotes vital
T313 394-396 IN denotes in
T314 397-406 JJ denotes embryonic
T315 413-424 NN denotes development
T316 407-412 NN denotes liver
T317 424-425 . denotes .
T318 425-506 sentence denotes However, targeted deletion of Mtf1 in the liver after birth is no longer lethal.
T319 426-433 RB denotes However
T320 486-488 VBZ denotes is
T321 433-435 , denotes ,
T322 435-443 VBN denotes targeted
T323 444-452 NN denotes deletion
T324 453-455 IN denotes of
T325 456-460 NN denotes Mtf1
T326 461-463 IN denotes in
T327 464-467 DT denotes the
T328 468-473 NN denotes liver
T329 474-479 IN denotes after
T330 480-485 NN denotes birth
T331 489-491 RB denotes no
T332 492-498 RB denotes longer
T333 499-505 JJ denotes lethal
T334 505-506 . denotes .
T239 0-3 CD denotes Two
R41 T279 T280 amod various,conditions
R42 T280 T278 pobj conditions,to
R7 T242 T240 amod major,branches
R8 T243 T240 prep of,branches
R9 T244 T245 amod anti-cadmium,defense
R10 T245 T243 pobj defense,of
R11 T246 T245 prep in,defense
R12 T247 T248 det the,mouse
R13 T248 T246 pobj mouse,in
R14 T249 T240 punct : ,branches
R15 T250 T251 nmod MTF,metallothioneins
R16 T251 T240 appos metallothioneins,branches
R17 T252 T250 punct -,MTF
R18 T253 T250 nummod 1,MTF
R19 T254 T251 punct /,metallothioneins
R20 T255 T251 cc and,metallothioneins
R21 T256 T251 conj glutathione,metallothioneins
R22 T259 T260 npadvmod Metal,responsive
R23 T260 T262 amod responsive,factor
R24 T261 T260 punct -,responsive
R25 T262 T264 nsubj factor,regulates
R26 T263 T262 compound transcription,factor
R27 T265 T262 nummod 1,factor
R28 T266 T262 punct (,factor
R29 T267 T262 appos MTF,factor
R30 T268 T267 punct -,MTF
R31 T269 T267 nummod 1,MTF
R32 T270 T264 punct ),regulates
R33 T271 T264 dobj expression,regulates
R34 T272 T271 prep of,expression
R35 T273 T274 poss its,genes
R36 T274 T272 pobj genes,of
R37 T275 T274 compound target,genes
R38 T276 T264 prep in,regulates
R39 T277 T276 pobj response,in
R40 T278 T277 prep to,response
R43 T281 T280 compound stress,conditions
R44 T282 T280 punct ", ",conditions
R45 T283 T284 advmod notably,load
R46 T284 T280 appos load,conditions
R47 T285 T286 amod heavy,metal
R48 T286 T284 compound metal,load
R49 T287 T264 punct ", ",regulates
R50 T288 T264 prep via,regulates
R51 T289 T288 pobj binding,via
R52 T290 T289 prep to,binding
R53 T291 T292 compound metal,elements
R54 T292 T290 pobj elements,to
R55 T293 T292 compound response,elements
R56 T294 T292 punct (,elements
R57 T295 T292 appos MREs,elements
R58 T296 T289 punct ),binding
R59 T297 T289 prep in,binding
R60 T298 T299 det the,regions
R61 T299 T297 pobj regions,in
R62 T300 T299 amod respective,regions
R63 T301 T302 compound enhancer,promoter
R64 T302 T299 compound promoter,regions
R65 T303 T302 punct /,promoter
R66 T304 T264 punct .,regulates
R67 T306 T307 advmod Furthermore,serves
R68 T308 T307 punct ", ",serves
R69 T309 T307 nsubj it,serves
R70 T310 T311 det a,function
R71 T311 T307 dobj function,serves
R72 T312 T311 amod vital,function
R73 T313 T307 prep in,serves
R74 T314 T315 amod embryonic,development
R75 T315 T313 pobj development,in
R76 T316 T315 compound liver,development
R77 T317 T307 punct .,serves
R78 T319 T320 advmod However,is
R79 T321 T320 punct ", ",is
R80 T322 T323 amod targeted,deletion
R81 T323 T320 nsubj deletion,is
R82 T324 T323 prep of,deletion
R83 T325 T324 pobj Mtf1,of
R84 T326 T323 prep in,deletion
R85 T327 T328 det the,liver
R86 T328 T326 pobj liver,in
R87 T329 T323 prep after,deletion
R88 T330 T329 pobj birth,after
R89 T331 T332 neg no,longer
R90 T332 T320 advmod longer,is
R91 T333 T320 acomp lethal,is
R92 T334 T320 punct .,is
R336 T239 T240 nummod Two,branches

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T80 35-42 GO:0006952 denotes defense
T81 50-55 NCBITaxon:10088 denotes mouse
T82 57-62 PR:000010717 denotes MTF-1
T83 84-95 CHEBI:16856 denotes glutathione
T84 106-145 PR:000010717 denotes Metal-responsive transcription factor 1
T85 147-152 PR:000010717 denotes MTF-1
T86 154-163 GO:0065007 denotes regulates
T87 164-174 GO:0010467 denotes expression
T88 189-194 SO:0000704 denotes genes
T89 327-335 SO:0000165 denotes enhancer
T90 336-344 SO:0000167 denotes promoter
T91 397-406 UBERON:0000922 denotes embryonic
T92 397-406 _FRAGMENT denotes embryonic
T93 413-424 GO:0009790 denotes development
T94 407-412 UBERON:0002107 denotes liver
T95 407-424 GO:0001889 denotes liver development
T96 456-460 PR:000010717 denotes Mtf1
T97 468-473 UBERON:0002107 denotes liver
T98 480-485 GO:0007567 denotes birth
R1 T93 T92 _lexicallyChainedTo development,embryonic

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T140 27-34 CHEBI_EXT:cadmium denotes cadmium
T141 35-42 GO:0006952 denotes defense
T142 50-55 NCBITaxon:10088 denotes mouse
T143 57-62 PR_EXT:000010717 denotes MTF-1
T144 84-95 CHEBI:16856 denotes glutathione
T145 106-111 CHEBI_EXT:metal denotes Metal
T146 106-145 PR_EXT:000010717 denotes Metal-responsive transcription factor 1
T147 123-136 GO_EXT:transcription denotes transcription
T148 123-143 GO_EXT:transcription_factor denotes transcription factor
T149 147-152 PR_EXT:000010717 denotes MTF-1
T150 154-163 GO:0065007 denotes regulates
T151 164-174 GO:0010467 denotes expression
T152 189-194 SO_EXT:0000704 denotes genes
T153 198-206 GO_EXT:reaction_or_response denotes response
T154 251-256 CHEBI_EXT:metal denotes metal
T155 267-274 CHEMINF_GO_EXT:chemical_binding_or_bond_formation denotes binding
T156 278-283 CHEBI_EXT:metal denotes metal
T157 284-292 GO_EXT:reaction_or_response denotes response
T158 327-335 SO_EXT:0000165 denotes enhancer
T159 336-344 SO_EXT:0000167 denotes promoter
T160 397-406 UBERON:0000922 denotes embryonic
T161 397-406 _FRAGMENT denotes embryonic
T162 413-424 GO:0009790 denotes development
T163 407-412 UBERON:0002107 denotes liver
T164 407-424 GO:0001889 denotes liver development
T165 444-452 SO_EXT:sequence_deletion_entity_or_process denotes deletion
T166 456-460 PR_EXT:000010717 denotes Mtf1
T167 468-473 UBERON:0002107 denotes liver
T168 480-485 GO:0007567 denotes birth
T169 499-505 GO_EXT:fatality_or_lethality denotes lethal
R4 T162 T161 _lexicallyChainedTo development,embryonic