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PMC:1208879 / 5135-5683 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T1550 0-4 RB denotes Here
T1551 8-14 VBP denotes report
T1552 5-7 PRP denotes we
T1553 15-18 DT denotes the
T1554 31-38 NNS denotes results
T1555 19-30 JJ denotes preliminary
T1556 39-41 IN denotes of
T1557 42-45 DT denotes the
T1558 63-69 NN denotes screen
T1559 46-51 JJ denotes first
T1560 52-62 JJ denotes systematic
T1561 70-73 IN denotes for
T1562 74-82 NN denotes proteins
T1563 83-87 WDT denotes that
T1564 88-96 VBP denotes interact
T1565 97-101 IN denotes with
T1566 102-106 NN denotes PAX6
T1567 106-107 . denotes .
T1568 107-273 sentence denotes We used sequence alignment algorithms and secondary structure prediction programs to define a new domain of 32 amino acids at the C-terminal end of the PAX6 protein.
T1569 108-110 PRP denotes We
T1570 111-115 VBD denotes used
T1571 116-124 NN denotes sequence
T1572 125-134 NN denotes alignment
T1573 135-145 NNS denotes algorithms
T1574 146-149 CC denotes and
T1575 150-159 JJ denotes secondary
T1576 160-169 NN denotes structure
T1577 170-180 NN denotes prediction
T1578 181-189 NNS denotes programs
T1579 190-192 TO denotes to
T1580 193-199 VB denotes define
T1581 200-201 DT denotes a
T1582 206-212 NN denotes domain
T1583 202-205 JJ denotes new
T1584 213-215 IN denotes of
T1585 216-218 CD denotes 32
T1586 225-230 NNS denotes acids
T1587 219-224 NN denotes amino
T1588 231-233 IN denotes at
T1589 234-237 DT denotes the
T1590 249-252 NN denotes end
T1591 238-239 NN denotes C
T1592 240-248 JJ denotes terminal
T1593 239-240 HYPH denotes -
T1594 253-255 IN denotes of
T1595 256-259 DT denotes the
T1596 265-272 NN denotes protein
T1597 260-264 NN denotes PAX6
T1598 272-273 . denotes .
T1599 273-436 sentence denotes We then screened a brain library with this peptide using the yeast two-hybrid technique and identified three novel interacting proteins, HOMER3, DNCL1 and TRIM11.
T1600 274-276 PRP denotes We
T1601 282-290 VBD denotes screened
T1602 277-281 RB denotes then
T1603 291-292 DT denotes a
T1604 299-306 NN denotes library
T1605 293-298 NN denotes brain
T1606 307-311 IN denotes with
T1607 312-316 DT denotes this
T1608 317-324 NN denotes peptide
T1609 325-330 VBG denotes using
T1610 331-334 DT denotes the
T1611 352-361 NN denotes technique
T1612 335-340 NN denotes yeast
T1613 341-344 CD denotes two
T1614 345-351 NN denotes hybrid
T1615 344-345 HYPH denotes -
T1616 362-365 CC denotes and
T1617 366-376 VBD denotes identified
T1618 377-382 CD denotes three
T1619 401-409 NN denotes proteins
T1620 383-388 JJ denotes novel
T1621 389-400 VBG denotes interacting
T1622 409-411 , denotes ,
T1623 411-417 NN denotes HOMER3
T1624 417-419 , denotes ,
T1625 419-424 NN denotes DNCL1
T1626 425-428 CC denotes and
T1627 429-435 NN denotes TRIM11
T1628 435-436 . denotes .
T1629 436-548 sentence denotes The interaction between PAX6 and these proteins was disrupted by naturally occurring C-terminal PAX6 mutations.
T1630 437-440 DT denotes The
T1631 441-452 NN denotes interaction
T1632 489-498 VBN denotes disrupted
T1633 453-460 IN denotes between
T1634 461-465 NN denotes PAX6
T1635 466-469 CC denotes and
T1636 470-475 DT denotes these
T1637 476-484 NN denotes proteins
T1638 485-488 VBD denotes was
T1639 499-501 IN denotes by
T1640 502-511 RB denotes naturally
T1641 512-521 VBG denotes occurring
T1642 538-547 NNS denotes mutations
T1643 522-523 NN denotes C
T1644 524-532 JJ denotes terminal
T1645 523-524 HYPH denotes -
T1646 533-537 NN denotes PAX6
T1647 547-548 . denotes .
R913 T1613 T1614 nummod two,hybrid
R916 T1614 T1611 compound hybrid,technique
R917 T1615 T1614 punct -,hybrid
R919 T1616 T1601 cc and,screened
R920 T1617 T1601 conj identified,screened
R921 T1618 T1619 nummod three,proteins
R923 T1619 T1617 dobj proteins,identified
R924 T1620 T1619 amod novel,proteins
R926 T1621 T1619 amod interacting,proteins
R927 T1622 T1619 punct ", ",proteins
R928 T1623 T1619 appos HOMER3,proteins
R929 T1624 T1623 punct ", ",HOMER3
R930 T1625 T1623 conj DNCL1,HOMER3
R931 T1626 T1625 cc and,DNCL1
R933 T1627 T1625 conj TRIM11,DNCL1
R934 T1628 T1601 punct .,screened
R936 T1630 T1631 det The,interaction
R937 T1631 T1632 nsubjpass interaction,disrupted
R939 T1633 T1631 prep between,interaction
R940 T1634 T1633 pobj PAX6,between
R942 T1635 T1634 cc and,PAX6
R943 T1636 T1637 det these,proteins
R945 T1637 T1634 conj proteins,PAX6
R946 T1638 T1632 auxpass was,disrupted
R947 T1639 T1632 agent by,disrupted
R949 T1640 T1641 advmod naturally,occurring
R950 T1641 T1642 amod occurring,mutations
R953 T1642 T1639 pobj mutations,by
R954 T1643 T1644 npadvmod C,terminal
R956 T1644 T1642 amod terminal,mutations
R958 T1645 T1644 punct -,terminal
R959 T1646 T1642 compound PAX6,mutations
R960 T1647 T1632 punct .,disrupted
R962 T1550 T1551 advmod Here,report
R963 T1552 T1551 nsubj we,report
R964 T1553 T1554 det the,results
R965 T1554 T1551 dobj results,report
R966 T1555 T1554 amod preliminary,results
R967 T1556 T1554 prep of,results
R968 T1557 T1558 det the,screen
R969 T1558 T1556 pobj screen,of
R970 T1559 T1558 amod first,screen
R971 T1560 T1558 amod systematic,screen
R972 T1561 T1558 prep for,screen
R973 T1562 T1561 pobj proteins,for
R974 T1563 T1564 dep that,interact
R975 T1564 T1562 relcl interact,proteins
R976 T1565 T1564 prep with,interact
R977 T1566 T1565 pobj PAX6,with
R978 T1567 T1551 punct .,report
R979 T1569 T1570 nsubj We,used
R980 T1571 T1572 compound sequence,alignment
R981 T1572 T1573 compound alignment,algorithms
R982 T1573 T1570 dobj algorithms,used
R983 T1574 T1573 cc and,algorithms
R984 T1575 T1576 amod secondary,structure
R985 T1576 T1577 compound structure,prediction
R986 T1577 T1578 compound prediction,programs
R987 T1578 T1573 conj programs,algorithms
R988 T1579 T1580 aux to,define
R989 T1580 T1570 advcl define,used
R990 T1581 T1582 det a,domain
R991 T1582 T1580 dobj domain,define
R992 T1583 T1582 amod new,domain
R993 T1584 T1582 prep of,domain
R994 T1585 T1586 nummod 32,acids
R995 T1586 T1584 pobj acids,of
R996 T1587 T1586 compound amino,acids
R997 T1588 T1580 prep at,define
R998 T1589 T1590 det the,end
R999 T1590 T1588 pobj end,at
R1000 T1591 T1592 npadvmod C,terminal
R1001 T1592 T1590 amod terminal,end
R1002 T1593 T1592 punct -,terminal
R1003 T1594 T1590 prep of,end
R1004 T1595 T1596 det the,protein
R1005 T1596 T1594 pobj protein,of
R1006 T1597 T1596 compound PAX6,protein
R1007 T1598 T1570 punct .,used
R1008 T1600 T1601 nsubj We,screened
R1009 T1602 T1601 advmod then,screened
R1010 T1603 T1604 det a,library
R1011 T1604 T1601 dobj library,screened
R1012 T1605 T1604 compound brain,library
R1013 T1606 T1601 prep with,screened
R1014 T1607 T1608 det this,peptide
R1015 T1608 T1606 pobj peptide,with
R1016 T1609 T1601 advcl using,screened
R1017 T1610 T1611 det the,technique
R1018 T1611 T1609 dobj technique,using
R1019 T1612 T1611 nmod yeast,technique

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T814 74-82 CHEBI_PR_EXT:protein denotes proteins
T815 102-106 PR_EXT:000012318 denotes PAX6
T816 116-124 SO_EXT:biological_sequence denotes sequence
T817 206-212 SO_EXT:0000417 denotes domain
T818 219-230 CHEBI_SO_EXT:amino_acid denotes amino acids
T819 238-248 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T820 260-264 PR_EXT:000012318 denotes PAX6
T821 265-272 CHEBI_PR_EXT:protein denotes protein
T822 293-298 UBERON:0000955 denotes brain
T823 317-324 CHEBI_SO_EXT:peptide_or_peptide_region denotes peptide
T824 335-340 NCBITaxon_EXT:yeast denotes yeast
T825 401-409 CHEBI_PR_EXT:protein denotes proteins
T826 411-417 PR_EXT:000008680 denotes HOMER3
T827 419-424 PR_EXT:000002325 denotes DNCL1
T828 429-435 PR_EXT:000016642 denotes TRIM11
T829 461-465 PR_EXT:000012318 denotes PAX6
T830 476-484 CHEBI_PR_EXT:protein denotes proteins
T831 522-532 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T832 533-537 PR_EXT:000012318 denotes PAX6
T833 538-547 SO_EXT:sequence_alteration_entity_or_process denotes mutations

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T656 102-106 PR:000012318 denotes PAX6
T657 206-212 SO:0000417 denotes domain
T658 260-264 PR:000012318 denotes PAX6
T659 293-298 UBERON:0000955 denotes brain
T660 411-417 PR:000008680 denotes HOMER3
T661 419-424 PR:000002325 denotes DNCL1
T662 429-435 PR:000016642 denotes TRIM11
T663 461-465 PR:000012318 denotes PAX6
T664 533-537 PR:000012318 denotes PAX6