PMC:1208879 / 4784-5134 JSONTXT

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    craft-sa-dev

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To date only three PAX6 protein-protein interactions have been described: with SOX2 on the lens-specific enhancer element of the δ-crystallin gene [22]; with MDIA, which modulates PAX6 activity in early neuronal development [23], and with MAF proteins on the glucagon promoter, which causes increased expression of this pancreatic hormone gene [17]."}

    craft-ca-core-ex-dev

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    craft-ca-core-dev

    {"project":"craft-ca-core-dev","denotations":[{"id":"T644","span":{"begin":20,"end":24},"obj":"PR:000012318"},{"id":"T645","span":{"begin":80,"end":84},"obj":"PR:000015426"},{"id":"T646","span":{"begin":106,"end":114},"obj":"SO:0000165"},{"id":"T647","span":{"begin":143,"end":147},"obj":"SO:0000704"},{"id":"T648","span":{"begin":171,"end":180},"obj":"GO:0065007"},{"id":"T649","span":{"begin":181,"end":185},"obj":"PR:000012318"},{"id":"T650","span":{"begin":204,"end":212},"obj":"CL:0000540"},{"id":"T651","span":{"begin":269,"end":277},"obj":"SO:0000167"},{"id":"T652","span":{"begin":302,"end":315},"obj":"_FRAGMENT"},{"id":"T653","span":{"begin":340,"end":344},"obj":"GO:0010467"},{"id":"T654","span":{"begin":321,"end":331},"obj":"UBERON:0001264"},{"id":"T655","span":{"begin":340,"end":344},"obj":"SO:0000704"}],"relations":[{"id":"R253","pred":"_lexicallyChainedTo","subj":"T653","obj":"T652"}],"text":" To date only three PAX6 protein-protein interactions have been described: with SOX2 on the lens-specific enhancer element of the δ-crystallin gene [22]; with MDIA, which modulates PAX6 activity in early neuronal development [23], and with MAF proteins on the glucagon promoter, which causes increased expression of this pancreatic hormone gene [17]."}