> top > docs > PMC:1189074 > spans > 5237-5966 > annotations

PMC:1189074 / 5237-5966 JSONTXT

Annnotations TAB JSON ListView MergeView

craft-sa-dev

Id Subject Object Predicate Lexical cue
T7247 10-18 NN denotes Strategy
T7248 19-22 IN denotes for
T7249 23-33 NN denotes Disruption
T7250 34-36 IN denotes of
T7251 37-40 DT denotes the
T7252 53-57 NN denotes Gene
T7253 41-46 NN denotes Mouse
T7254 47-52 NN denotes Acadm
T7255 57-175 sentence denotes (A) The MCAD IV2 insertion targeting vector with a deleted 1.3-kb region encompassing exon 10 and flanking sequences.
T7256 58-59 -LRB- denotes (
T7257 59-60 LS denotes A
T7258 95-101 NN denotes vector
T7259 60-61 -RRB- denotes )
T7260 62-65 DT denotes The
T7261 66-70 NN denotes MCAD
T7262 75-84 NN denotes insertion
T7263 71-74 NN denotes IV2
T7264 85-94 NN denotes targeting
T7265 102-106 IN denotes with
T7266 107-108 DT denotes a
T7267 124-130 NN denotes region
T7268 109-116 VBN denotes deleted
T7269 117-120 CD denotes 1.3
T7270 121-123 NN denotes kb
T7271 120-121 HYPH denotes -
T7272 131-143 VBG denotes encompassing
T7273 144-148 NN denotes exon
T7274 149-151 CD denotes 10
T7275 152-155 CC denotes and
T7276 156-164 VBG denotes flanking
T7277 165-174 NNS denotes sequences
T7278 174-175 . denotes .
T7279 175-339 sentence denotes MCAD IV2 undergoes gap repair upon homologous recombination at the endogenous Acadm locus resulting in a duplication of exons 8, 9, and 10 at the disrupted allele.
T7280 176-180 NN denotes MCAD
T7281 181-184 NN denotes IV2
T7282 185-194 VBZ denotes undergoes
T7283 195-198 NN denotes gap
T7284 199-205 NN denotes repair
T7285 206-210 IN denotes upon
T7286 211-221 JJ denotes homologous
T7287 222-235 NN denotes recombination
T7288 236-238 IN denotes at
T7289 239-242 DT denotes the
T7290 260-265 NN denotes locus
T7291 243-253 JJ denotes endogenous
T7292 254-259 NN denotes Acadm
T7293 266-275 VBG denotes resulting
T7294 276-278 IN denotes in
T7295 279-280 DT denotes a
T7296 281-292 NN denotes duplication
T7297 293-295 IN denotes of
T7298 296-301 NNS denotes exons
T7299 302-303 CD denotes 8
T7300 303-305 , denotes ,
T7301 305-306 CD denotes 9
T7302 306-308 , denotes ,
T7303 308-311 CC denotes and
T7304 312-314 CD denotes 10
T7305 315-317 IN denotes at
T7306 318-321 DT denotes the
T7307 332-338 NN denotes allele
T7308 322-331 VBN denotes disrupted
T7309 338-339 . denotes .
T7310 339-427 sentence denotes (B) Southern blot analysis of EcoRI-digested genomic DNA from ES cells screened by PCR.
T7311 340-341 -LRB- denotes (
T7312 341-342 LS denotes B
T7313 358-366 NN denotes analysis
T7314 342-343 -RRB- denotes )
T7315 344-352 NNP denotes Southern
T7316 353-357 NN denotes blot
T7317 367-369 IN denotes of
T7318 370-375 NN denotes EcoRI
T7319 376-384 VBN denotes digested
T7320 375-376 HYPH denotes -
T7321 393-396 NN denotes DNA
T7322 385-392 JJ denotes genomic
T7323 397-401 IN denotes from
T7324 402-404 NN denotes ES
T7325 405-410 NNS denotes cells
T7326 411-419 VBN denotes screened
T7327 420-422 IN denotes by
T7328 423-426 NN denotes PCR
T7329 426-427 . denotes .
T7330 427-634 sentence denotes Probe A, a DNA fragment consisting of a portion of exon 10 that is not present in the targeting vector, hybridizes to an endogenous 3.1-kb fragment and, upon homologous recombination, to a 13.2-kb fragment.
T7331 428-433 NN denotes Probe
T7332 434-435 NN denotes A
T7333 532-542 VBZ denotes hybridizes
T7334 435-437 , denotes ,
T7335 437-438 DT denotes a
T7336 443-451 NN denotes fragment
T7337 439-442 NN denotes DNA
T7338 452-462 VBG denotes consisting
T7339 463-465 IN denotes of
T7340 466-467 DT denotes a
T7341 468-475 NN denotes portion
T7342 476-478 IN denotes of
T7343 479-483 NN denotes exon
T7344 484-486 CD denotes 10
T7345 487-491 WDT denotes that
T7346 492-494 VBZ denotes is
T7347 495-498 RB denotes not
T7348 499-506 JJ denotes present
T7349 507-509 IN denotes in
T7350 510-513 DT denotes the
T7351 524-530 NN denotes vector
T7352 514-523 NN denotes targeting
T7353 530-532 , denotes ,
T7354 543-545 IN denotes to
T7355 546-548 DT denotes an
T7356 567-575 NN denotes fragment
T7357 549-559 JJ denotes endogenous
T7358 560-563 CD denotes 3.1
T7359 564-566 NN denotes kb
T7360 563-564 HYPH denotes -
T7361 576-579 CC denotes and
T7362 579-581 , denotes ,
T7363 581-585 IN denotes upon
T7364 612-614 IN denotes to
T7365 586-596 JJ denotes homologous
T7366 597-610 NN denotes recombination
T7367 610-612 , denotes ,
T7368 615-616 DT denotes a
T7369 625-633 NN denotes fragment
T7370 617-621 CD denotes 13.2
T7371 622-624 NN denotes kb
T7372 621-622 HYPH denotes -
T7373 633-634 . denotes .
T7374 634-729 sentence denotes Lane 1 represents a wild-type ES cell line, and Lane 2 and 3 represent targeted ES cell lines.
T7375 635-639 NN denotes Lane
T7376 642-652 VBZ denotes represents
T7377 640-641 CD denotes 1
T7378 653-654 DT denotes a
T7379 673-677 NN denotes line
T7380 655-659 JJ denotes wild
T7381 660-664 NN denotes type
T7382 659-660 HYPH denotes -
T7383 665-667 NN denotes ES
T7384 668-672 NN denotes cell
T7385 677-679 , denotes ,
T7386 679-682 CC denotes and
T7387 683-687 NN denotes Lane
T7388 688-689 CD denotes 2
T7389 696-705 VBP denotes represent
T7390 690-693 CC denotes and
T7391 694-695 CD denotes 3
T7392 706-714 VBN denotes targeted
T7393 723-728 NNS denotes lines
T7394 715-717 NN denotes ES
T7395 718-722 NN denotes cell
T7396 728-729 . denotes .
R4678 T7248 T7247 prep for,Strategy
R4679 T7249 T7248 pobj Disruption,for
R4680 T7250 T7249 prep of,Disruption
R4681 T7251 T7252 det the,Gene
R4682 T7252 T7250 pobj Gene,of
R4683 T7253 T7252 compound Mouse,Gene
R4684 T7254 T7252 compound Acadm,Gene
R4685 T7256 T7257 punct (,A
R4686 T7257 T7258 meta A,vector
R4687 T7259 T7257 punct ),A
R4688 T7260 T7258 det The,vector
R4689 T7261 T7262 compound MCAD,insertion
R4690 T7262 T7258 compound insertion,vector
R4691 T7263 T7262 compound IV2,insertion
R4692 T7264 T7258 compound targeting,vector
R4693 T7265 T7258 prep with,vector
R4694 T7266 T7267 det a,region
R4695 T7267 T7265 pobj region,with
R4696 T7268 T7267 amod deleted,region
R4697 T7269 T7270 nummod 1.3,kb
R4698 T7270 T7267 compound kb,region
R4699 T7271 T7270 punct -,kb
R4700 T7272 T7267 acl encompassing,region
R4701 T7273 T7272 dobj exon,encompassing
R4702 T7274 T7273 nummod 10,exon
R4703 T7275 T7273 cc and,exon
R4704 T7276 T7277 amod flanking,sequences
R4705 T7277 T7273 conj sequences,exon
R4706 T7278 T7258 punct .,vector
R4707 T7280 T7281 compound MCAD,IV2
R4708 T7281 T7282 nsubj IV2,undergoes
R4709 T7283 T7284 compound gap,repair
R4710 T7284 T7282 dobj repair,undergoes
R4711 T7285 T7282 prep upon,undergoes
R4712 T7286 T7287 amod homologous,recombination
R4713 T7287 T7285 pobj recombination,upon
R4714 T7288 T7282 prep at,undergoes
R4715 T7289 T7290 det the,locus
R4716 T7290 T7288 pobj locus,at
R4717 T7291 T7290 amod endogenous,locus
R4718 T7292 T7290 compound Acadm,locus
R4719 T7293 T7282 advcl resulting,undergoes
R4720 T7294 T7293 prep in,resulting
R4721 T7295 T7296 det a,duplication
R4722 T7296 T7294 pobj duplication,in
R4723 T7297 T7296 prep of,duplication
R4724 T7298 T7299 nmod exons,8
R4725 T7299 T7297 pobj 8,of
R4726 T7300 T7299 punct ", ",8
R4727 T7301 T7299 conj 9,8
R4728 T7302 T7301 punct ", ",9
R4729 T7303 T7301 cc and,9
R4730 T7304 T7301 conj 10,9
R4731 T7305 T7296 prep at,duplication
R4732 T7306 T7307 det the,allele
R4733 T7307 T7305 pobj allele,at
R4734 T7308 T7307 amod disrupted,allele
R4735 T7309 T7282 punct .,undergoes
R4736 T7311 T7312 punct (,B
R4737 T7312 T7313 meta B,analysis
R4738 T7314 T7312 punct ),B
R4739 T7315 T7316 compound Southern,blot
R4740 T7316 T7313 compound blot,analysis
R4741 T7317 T7313 prep of,analysis
R4742 T7318 T7319 npadvmod EcoRI,digested
R4743 T7319 T7321 amod digested,DNA
R4744 T7320 T7319 punct -,digested
R4745 T7321 T7317 pobj DNA,of
R4746 T7322 T7321 amod genomic,DNA
R4747 T7323 T7321 prep from,DNA
R4748 T7324 T7325 compound ES,cells
R4749 T7325 T7323 pobj cells,from
R4750 T7326 T7325 acl screened,cells
R4751 T7327 T7326 prep by,screened
R4752 T7328 T7327 pobj PCR,by
R4753 T7329 T7313 punct .,analysis
R4754 T7331 T7332 compound Probe,A
R4755 T7332 T7333 nsubj A,hybridizes
R4756 T7334 T7332 punct ", ",A
R4757 T7335 T7336 det a,fragment
R4758 T7336 T7332 appos fragment,A
R4759 T7337 T7336 compound DNA,fragment
R4760 T7338 T7336 acl consisting,fragment
R4761 T7339 T7338 prep of,consisting
R4762 T7340 T7341 det a,portion
R4763 T7341 T7339 pobj portion,of
R4764 T7342 T7341 prep of,portion
R4765 T7343 T7342 pobj exon,of
R4766 T7344 T7343 nummod 10,exon
R4767 T7345 T7346 dep that,is
R4768 T7346 T7341 relcl is,portion
R4769 T7347 T7346 neg not,is
R4770 T7348 T7346 acomp present,is
R4771 T7349 T7346 prep in,is
R4772 T7350 T7351 det the,vector
R4773 T7351 T7349 pobj vector,in
R4774 T7352 T7351 compound targeting,vector
R4775 T7353 T7333 punct ", ",hybridizes
R4776 T7354 T7333 prep to,hybridizes
R4777 T7355 T7356 det an,fragment
R4778 T7356 T7354 pobj fragment,to
R4779 T7357 T7356 amod endogenous,fragment
R4780 T7358 T7359 nummod 3.1,kb
R4781 T7359 T7356 compound kb,fragment
R4782 T7360 T7359 punct -,kb
R4783 T7361 T7333 cc and,hybridizes
R4784 T7362 T7333 punct ", ",hybridizes
R4785 T7363 T7364 prep upon,to
R4786 T7364 T7333 conj to,hybridizes
R4787 T7365 T7366 amod homologous,recombination
R4788 T7366 T7363 pobj recombination,upon
R4789 T7367 T7364 punct ", ",to
R4790 T7368 T7369 det a,fragment
R4791 T7369 T7364 pobj fragment,to
R4792 T7370 T7371 nummod 13.2,kb
R4793 T7371 T7369 compound kb,fragment
R4794 T7372 T7371 punct -,kb
R4795 T7373 T7333 punct .,hybridizes
R4796 T7375 T7376 nsubj Lane,represents
R4797 T7377 T7375 nummod 1,Lane
R4798 T7378 T7379 det a,line
R4799 T7379 T7376 dobj line,represents
R4800 T7380 T7381 amod wild,type
R4801 T7381 T7379 compound type,line
R4802 T7382 T7381 punct -,type
R4803 T7383 T7379 compound ES,line
R4804 T7384 T7379 compound cell,line
R4805 T7385 T7376 punct ", ",represents
R4806 T7386 T7376 cc and,represents
R4807 T7387 T7388 nmod Lane,2
R4808 T7388 T7389 nsubj 2,represent
R4809 T7389 T7376 conj represent,represents
R4810 T7390 T7388 cc and,2
R4811 T7391 T7388 conj 3,2
R4812 T7392 T7393 amod targeted,lines
R4813 T7393 T7389 dobj lines,represent
R4814 T7394 T7393 compound ES,lines
R4815 T7395 T7393 compound cell,lines
R4816 T7396 T7389 punct .,represent

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7397 41-46 NCBITaxon:10088 denotes Mouse
T7398 53-57 SO:0000704 denotes Gene
T7399 85-101 SO:0001644 denotes targeting vector
T7400 144-148 SO:0000147 denotes exon
T7401 156-164 SO:0000357 denotes flanking
T7402 296-301 SO:0000147 denotes exons
T7403 332-338 SO:0001023 denotes allele
T7404 385-392 SO:0001026 denotes genomic
T7405 402-410 CL:0002322 denotes ES cells
T7406 468-483 SO:0000852 denotes portion of exon
T7407 514-530 SO:0001644 denotes targeting vector
T7408 532-542 GO:0097617 denotes hybridizes
T7409 665-672 CL:0002322 denotes ES cell
T7410 715-722 CL:0002322 denotes ES cell

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T7411 41-46 NCBITaxon:10088 denotes Mouse
T7412 47-52 GO_PR_EXT:medium_chain_acyl_CoA_dehydrogenase denotes Acadm
T7413 53-57 SO_EXT:0000704 denotes Gene
T7414 66-70 GO_PR_EXT:medium_chain_acyl_CoA_dehydrogenase denotes MCAD
T7415 75-84 SO_EXT:sequence_insertion_entity_or_process denotes insertion
T7416 85-101 SO_EXT:0001644 denotes targeting vector
T7417 109-116 SO_EXT:sequence_deletion_process denotes deleted
T7418 122-123 CHEBI_SO_EXT:base denotes b
T7419 144-148 SO_EXT:0000147 denotes exon
T7420 156-164 SO:0000357 denotes flanking
T7421 165-174 SO_EXT:biological_sequence denotes sequences
T7422 176-180 GO_PR_EXT:medium_chain_acyl_CoA_dehydrogenase denotes MCAD
T7423 195-205 GO_EXT:DNA_gap_repair denotes gap repair
T7424 222-235 GO_SO_EXT:sequence_rearrangement_process denotes recombination
T7425 254-259 GO_PR_EXT:medium_chain_acyl_CoA_dehydrogenase denotes Acadm
T7426 281-292 SO_EXT:sequence_duplication_entity_or_process denotes duplication
T7427 296-301 SO_EXT:0000147 denotes exons
T7428 332-338 SO_EXT:0001023 denotes allele
T7429 385-396 SO_EXT:genomic_DNA denotes genomic DNA
T7430 393-396 CHEBI_SO_EXT:DNA denotes DNA
T7431 402-410 CL:0002322 denotes ES cells
T7432 405-410 CL_GO_EXT:cell denotes cells
T7433 428-433 CHEBI_SO_EXT:molecular_probe denotes Probe
T7434 439-442 CHEBI_SO_EXT:DNA denotes DNA
T7435 468-483 SO_EXT:0000852 denotes portion of exon
T7436 514-530 SO_EXT:0001644 denotes targeting vector
T7437 532-542 GO:0097617 denotes hybridizes
T7438 565-566 CHEBI_SO_EXT:base denotes b
T7439 597-610 GO_SO_EXT:sequence_rearrangement_process denotes recombination
T7440 623-624 CHEBI_SO_EXT:base denotes b
T7441 655-664 SO_EXT:wild_type_entity_or_quality denotes wild-type
T7442 665-672 CL:0002322 denotes ES cell
T7443 668-672 CL_GO_EXT:cell denotes cell
T7444 715-722 CL:0002322 denotes ES cell
T7445 718-722 CL_GO_EXT:cell denotes cell