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patients with ESCS display three types of abnormality attributable to the retina: (1) an atypical ERG waveform that is preferentially sensitive to short-wavelength light, (2) slowly progressive retinal degeneration, and (3) abnormal retinal lamination with rosette formation [1,12,13]. The rd7 mutant mice also demonstrate the latter two defects, but have a normal ERG [15,45]. These similarities and differences between the two species help to explain the possible mechanistic basis of the ESCS."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T8259","span":{"begin":0,"end":5},"obj":"NCBITaxon:9606"},{"id":"T8260","span":{"begin":80,"end":86},"obj":"UBERON:0000966"},{"id":"T8261","span":{"begin":200,"end":207},"obj":"UBERON:0000966"},{"id":"T8262","span":{"begin":239,"end":246},"obj":"UBERON:0000966"},{"id":"T8263","span":{"begin":300,"end":306},"obj":"SO_EXT:sequence_altered_entity_or_alteration_process"},{"id":"T8264","span":{"begin":307,"end":311},"obj":"NCBITaxon:10088"},{"id":"T8265","span":{"begin":435,"end":442},"obj":"NCBITaxon:species"}],"text":"Human patients with ESCS display three types of abnormality attributable to the retina: (1) an atypical ERG waveform that is preferentially sensitive to short-wavelength light, (2) slowly progressive retinal degeneration, and (3) abnormal retinal lamination with rosette formation [1,12,13]. The rd7 mutant mice also demonstrate the latter two defects, but have a normal ERG [15,45]. These similarities and differences between the two species help to explain the possible mechanistic basis of the ESCS."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T7696","span":{"begin":0,"end":5},"obj":"NCBITaxon:9606"},{"id":"T7697","span":{"begin":80,"end":86},"obj":"UBERON:0000966"},{"id":"T7698","span":{"begin":200,"end":207},"obj":"UBERON:0000966"},{"id":"T7699","span":{"begin":239,"end":246},"obj":"UBERON:0000966"},{"id":"T7700","span":{"begin":307,"end":311},"obj":"NCBITaxon:10088"},{"id":"T7701","span":{"begin":435,"end":442},"obj":"NCBITaxon:species"}],"text":"Human patients with ESCS display three types of abnormality attributable to the retina: (1) an atypical ERG waveform that is preferentially sensitive to short-wavelength light, (2) slowly progressive retinal degeneration, and (3) abnormal retinal lamination with rosette formation [1,12,13]. The rd7 mutant mice also demonstrate the latter two defects, but have a normal ERG [15,45]. These similarities and differences between the two species help to explain the possible mechanistic basis of the ESCS."}

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