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This finding is consistent with the normal expression pattern and function of Thrb2 in the rd7 mutant.\nOne further finding to note is that the cell bodies of the M-opsin–positive cells appear to be scattered throughout the ONL in the rd7 mutant at P14 (Figure S8). Despite this fact, their overall number does not appear to be increased relative to wild-type. In addition, by P28, the M-opsin-positive cell bodies in rd7 appear to have relocated to their normal position at the scleral edge of the ONL (Figure S8). It is known that until P11, the cell bodies of cone photoreceptors in the mouse are normally dispersed throughout the ONL, only to relocate subsequently to the scleral edge of the ONL around P12 [23]. 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