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PMC:1183529 / 29779-30609 JSONTXT

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craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T15210 11-15 NCBITaxon:10088 denotes mice
T15211 29-33 PR:000033987 denotes lacZ
T15212 34-38 SO:0000704 denotes gene
T15213 53-57 PR:000017653 denotes Fog2
T15214 58-66 SO:0000167 denotes promoter
T15215 112-119 NCBITaxon:33208 denotes animals
T15216 125-129 PR:000033987 denotes lacZ
T15217 130-134 SO:0000704 denotes gene
T15218 175-179 PR:000017653 denotes Fog2
T15219 211-221 GO:0010467 denotes expression
T15220 242-250 SO:0001817 denotes in frame
T15221 289-293 PR:000017653 denotes FOG2
T15222 307-311 PR:000017653 denotes Fog2
T15223 312-316 PR:000033987 denotes lacZ
T15224 342-346 SO:0000243 denotes ires
T15225 352-360 SO:0005853 denotes cassette
T15226 382-388 SO:0001023 denotes allele
T15227 392-396 PR:000017653 denotes Fog2
T15228 397-401 SO:0000704 denotes gene
T15229 407-411 PR:000017653 denotes Fog2
T15230 412-416 PR:000033987 denotes LacZ
T15231 489-497 CL:0002322 denotes ES cells
T15232 598-609 UBERON:0000358 denotes blastocysts
T15233 611-615 PR:000017653 denotes Fog2
T15234 616-620 PR:000033987 denotes lacZ
T15235 626-633 NCBITaxon:33208 denotes animals
T15236 688-692 PR:000033987 denotes lacZ
T15237 693-703 GO:0010467 denotes Expression
T15238 723-732 UBERON:0000922 denotes embryonic
T15239 733-738 UBERON:0002048 denotes lungs
T15240 798-803 CHEBI:75055 denotes X-gal

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T15270 0-10 SO_EXT:transgenic_entity denotes Transgenic
T15271 11-15 NCBITaxon:10088 denotes mice
T15272 29-33 PR_EXT:000033987 denotes lacZ
T15273 34-38 SO_EXT:0000704 denotes gene
T15274 53-57 PR_EXT:000017653 denotes Fog2
T15275 58-66 SO_EXT:0000167 denotes promoter
T15276 112-119 NCBITaxon:33208 denotes animals
T15277 125-129 PR_EXT:000033987 denotes lacZ
T15278 130-134 SO_EXT:0000704 denotes gene
T15279 175-179 PR_EXT:000017653 denotes Fog2
T15280 195-210 GO_EXT:0004565 denotes β-galactosidase
T15281 211-221 GO:0010467 denotes expression
T15282 227-233 SO_EXT:sequence_fusion_entity_or_process denotes fusion
T15283 234-241 CHEBI_PR_EXT:protein denotes protein
T15284 242-250 SO:0001817 denotes in frame
T15285 270-281 CHEBI_SO_EXT:amino_acid denotes amino acids
T15286 289-293 PR_EXT:000017653 denotes FOG2
T15287 294-301 CHEBI_PR_EXT:protein denotes protein
T15288 307-311 PR_EXT:000017653 denotes Fog2
T15289 312-316 PR_EXT:000033987 denotes lacZ
T15290 342-346 SO_EXT:0000243 denotes ires
T15291 352-360 SO_EXT:0005853 denotes cassette
T15292 377-381 SO_EXT:sequence_nullness denotes null
T15293 382-388 SO_EXT:0001023 denotes allele
T15294 392-396 PR_EXT:000017653 denotes Fog2
T15295 397-401 SO_EXT:0000704 denotes gene
T15296 407-411 PR_EXT:000017653 denotes Fog2
T15297 412-416 PR_EXT:000033987 denotes LacZ
T15298 422-431 SO_EXT:engineered_biological_sequence denotes construct
T15299 436-446 SO_EXT:sequence_linearization denotes linearized
T15300 489-497 CL:0002322 denotes ES cells
T15301 492-497 CL_GO_EXT:cell denotes cells
T15302 522-527 SO_EXT:sequence_cloned_entity denotes clone
T15303 598-609 UBERON:0000358 denotes blastocysts
T15304 611-615 PR_EXT:000017653 denotes Fog2
T15305 616-620 PR_EXT:000033987 denotes lacZ
T15306 626-633 NCBITaxon:33208 denotes animals
T15307 688-692 PR_EXT:000033987 denotes lacZ
T15308 693-703 GO:0010467 denotes Expression
T15309 723-732 UBERON:0000922 denotes embryonic
T15310 733-738 UBERON:0002048 denotes lungs
T15311 768-783 GO_EXT:0015925 denotes β-galactosidase
T15312 798-803 CHEBI:75055 denotes X-gal

craft-sa-dev

Id Subject Object Predicate Lexical cue
T15547 0-10 JJ denotes Transgenic
T15548 11-15 NNS denotes mice
T15549 77-86 VBN denotes developed
T15550 16-24 VBG denotes carrying
T15551 25-28 DT denotes the
T15552 34-38 NN denotes gene
T15553 29-33 NN denotes lacZ
T15554 39-45 VBN denotes driven
T15555 46-48 IN denotes by
T15556 49-52 DT denotes the
T15557 58-66 NN denotes promoter
T15558 53-57 NN denotes Fog2
T15559 67-71 VBP denotes have
T15560 72-76 VBN denotes been
T15561 87-89 IN denotes by
T15562 90-92 NNP denotes S.
T15563 93-101 NNP denotes Tevosian
T15564 101-102 . denotes .
T15565 102-302 sentence denotes In these animals, the lacZ gene is incorporated (“knocked-in”) into the Fog2 locus to allow β-galactosidase expression as a fusion protein in frame with the first 235 amino acids of the FOG2 protein.
T15566 103-105 IN denotes In
T15567 138-150 VBN denotes incorporated
T15568 106-111 DT denotes these
T15569 112-119 NNS denotes animals
T15570 119-121 , denotes ,
T15571 121-124 DT denotes the
T15572 130-134 NN denotes gene
T15573 125-129 NN denotes lacZ
T15574 135-137 VBZ denotes is
T15575 151-152 -LRB- denotes (
T15576 153-160 VBN denotes knocked
T15577 152-153 `` denotes “
T15578 160-161 HYPH denotes -
T15579 161-163 RP denotes in
T15580 163-164 '' denotes ”
T15581 164-165 -RRB- denotes )
T15582 166-170 IN denotes into
T15583 171-174 DT denotes the
T15584 180-185 NN denotes locus
T15585 175-179 NN denotes Fog2
T15586 186-188 TO denotes to
T15587 189-194 VB denotes allow
T15588 195-196 NN denotes β
T15589 197-210 NN denotes galactosidase
T15590 196-197 HYPH denotes -
T15591 211-221 NN denotes expression
T15592 222-224 IN denotes as
T15593 225-226 DT denotes a
T15594 234-241 NN denotes protein
T15595 227-233 NN denotes fusion
T15596 242-244 IN denotes in
T15597 245-250 NN denotes frame
T15598 251-255 IN denotes with
T15599 256-259 DT denotes the
T15600 276-281 NNS denotes acids
T15601 260-265 JJ denotes first
T15602 266-269 CD denotes 235
T15603 270-275 NN denotes amino
T15604 282-284 IN denotes of
T15605 285-288 DT denotes the
T15606 294-301 NN denotes protein
T15607 289-293 NN denotes FOG2
T15608 301-302 . denotes .
T15609 302-361 sentence denotes The Fog2-lacZ module is followed by an ires-eGFP cassette.
T15610 303-306 DT denotes The
T15611 317-323 NN denotes module
T15612 307-311 NN denotes Fog2
T15613 312-316 NN denotes lacZ
T15614 311-312 HYPH denotes -
T15615 327-335 VBN denotes followed
T15616 324-326 VBZ denotes is
T15617 336-338 IN denotes by
T15618 339-341 DT denotes an
T15619 352-360 NN denotes cassette
T15620 342-346 NN denotes ires
T15621 347-351 NN denotes eGFP
T15622 346-347 HYPH denotes -
T15623 360-361 . denotes .
T15624 361-402 sentence denotes This creates a null allele of Fog2 gene.
T15625 362-366 DT denotes This
T15626 367-374 VBZ denotes creates
T15627 375-376 DT denotes a
T15628 382-388 NN denotes allele
T15629 377-381 JJ denotes null
T15630 389-391 IN denotes of
T15631 392-396 NN denotes Fog2
T15632 397-401 NN denotes gene
T15633 401-402 . denotes .
T15634 402-498 sentence denotes The Fog2-LacZ-eGFP construct was linearized with KspI and electroporated into the CJ7 ES cells.
T15635 403-406 DT denotes The
T15636 422-431 NN denotes construct
T15637 407-411 NN denotes Fog2
T15638 417-421 NN denotes eGFP
T15639 411-412 HYPH denotes -
T15640 412-416 NN denotes LacZ
T15641 416-417 HYPH denotes -
T15642 436-446 VBN denotes linearized
T15643 432-435 VBD denotes was
T15644 447-451 IN denotes with
T15645 452-456 NN denotes KspI
T15646 457-460 CC denotes and
T15647 461-475 VBN denotes electroporated
T15648 476-480 IN denotes into
T15649 481-484 DT denotes the
T15650 492-497 NNS denotes cells
T15651 485-488 NN denotes CJ7
T15652 489-491 NN denotes ES
T15653 497-498 . denotes .
T15654 498-610 sentence denotes The correctly targeted clone was selected by the Southern blot analysis and injected into C57BL/6J blastocysts.
T15655 499-502 DT denotes The
T15656 522-527 NN denotes clone
T15657 503-512 RB denotes correctly
T15658 513-521 VBN denotes targeted
T15659 532-540 VBN denotes selected
T15660 528-531 VBD denotes was
T15661 541-543 IN denotes by
T15662 544-547 DT denotes the
T15663 562-570 NN denotes analysis
T15664 548-556 NNP denotes Southern
T15665 557-561 NN denotes blot
T15666 571-574 CC denotes and
T15667 575-583 VBN denotes injected
T15668 584-588 IN denotes into
T15669 589-594 NN denotes C57BL
T15670 595-597 NN denotes 6J
T15671 594-595 HYPH denotes /
T15672 598-609 NNS denotes blastocysts
T15673 609-610 . denotes .
T15674 610-687 sentence denotes Fog2-lacZ-eGFP animals were maintained on the mixed C57BL/6J/129 background.
T15675 611-615 NN denotes Fog2
T15676 621-625 NN denotes eGFP
T15677 615-616 HYPH denotes -
T15678 616-620 NN denotes lacZ
T15679 620-621 HYPH denotes -
T15680 626-633 NNS denotes animals
T15681 639-649 VBN denotes maintained
T15682 634-638 VBD denotes were
T15683 650-652 IN denotes on
T15684 653-656 DT denotes the
T15685 676-686 NN denotes background
T15686 657-662 JJ denotes mixed
T15687 663-668 NN denotes C57BL
T15688 669-671 NN denotes 6J
T15689 668-669 HYPH denotes /
T15690 671-672 HYPH denotes /
T15691 672-675 CD denotes 129
T15692 686-687 . denotes .
T15693 687-830 sentence denotes lacZ Expression in whole dissected embryonic lungs was analyzed by staining for β-galactosidase activity with X-gal after fixation for 30 min.
T15694 688-692 NN denotes lacZ
T15695 693-703 NN denotes Expression
T15696 743-751 VBN denotes analyzed
T15697 704-706 IN denotes in
T15698 707-712 JJ denotes whole
T15699 733-738 NNS denotes lungs
T15700 713-722 VBN denotes dissected
T15701 723-732 JJ denotes embryonic
T15702 739-742 VBD denotes was
T15703 752-754 IN denotes by
T15704 755-763 VBG denotes staining
T15705 764-767 IN denotes for
T15706 768-769 NN denotes β
T15707 770-783 NN denotes galactosidase
T15708 769-770 HYPH denotes -
T15709 784-792 NN denotes activity
T15710 793-797 IN denotes with
T15711 798-799 NN denotes X
T15712 800-803 NN denotes gal
T15713 799-800 HYPH denotes -
T15714 804-809 IN denotes after
T15715 810-818 NN denotes fixation
T15716 819-822 IN denotes for
T15717 823-825 CD denotes 30
T15718 826-829 NN denotes min
T15719 829-830 . denotes .
R4421 T15547 T15548 amod Transgenic,mice
R4422 T15548 T15549 nsubjpass mice,developed
R4423 T15550 T15548 acl carrying,mice
R4424 T15551 T15552 det the,gene
R4425 T15552 T15550 dobj gene,carrying
R4426 T15553 T15552 compound lacZ,gene
R4427 T15554 T15552 acl driven,gene
R4428 T15555 T15554 agent by,driven
R4429 T15556 T15557 det the,promoter
R4430 T15557 T15555 pobj promoter,by
R4431 T15558 T15557 compound Fog2,promoter
R4432 T15559 T15549 aux have,developed
R4433 T15560 T15549 auxpass been,developed
R4434 T15561 T15549 agent by,developed
R4435 T15562 T15563 compound S.,Tevosian
R4436 T15563 T15561 pobj Tevosian,by
R4437 T15564 T15549 punct .,developed
R4438 T15566 T15567 prep In,incorporated
R4439 T15568 T15569 det these,animals
R4440 T15569 T15566 pobj animals,In
R4441 T15570 T15567 punct ", ",incorporated
R4442 T15571 T15572 det the,gene
R4443 T15572 T15567 nsubjpass gene,incorporated
R4444 T15573 T15572 compound lacZ,gene
R4445 T15574 T15567 auxpass is,incorporated
R4446 T15575 T15576 punct (,knocked
R4447 T15576 T15567 parataxis knocked,incorporated
R4448 T15577 T15576 punct “,knocked
R4449 T15578 T15576 punct -,knocked
R4450 T15579 T15576 prt in,knocked
R4451 T15580 T15576 punct ”,knocked
R4452 T15581 T15576 punct ),knocked
R4453 T15582 T15567 prep into,incorporated
R4454 T15583 T15584 det the,locus
R4455 T15584 T15582 pobj locus,into
R4456 T15585 T15584 compound Fog2,locus
R4457 T15586 T15587 aux to,allow
R4458 T15587 T15567 advcl allow,incorporated
R4459 T15588 T15589 compound β,galactosidase
R4460 T15589 T15591 compound galactosidase,expression
R4461 T15590 T15589 punct -,galactosidase
R4462 T15591 T15587 dobj expression,allow
R4463 T15592 T15587 prep as,allow
R4464 T15593 T15594 det a,protein
R4465 T15594 T15592 pobj protein,as
R4466 T15595 T15594 compound fusion,protein
R4467 T15596 T15594 prep in,protein
R4468 T15597 T15596 pobj frame,in
R4469 T15598 T15597 prep with,frame
R4470 T15599 T15600 det the,acids
R4471 T15600 T15598 pobj acids,with
R4472 T15601 T15600 amod first,acids
R4473 T15602 T15600 nummod 235,acids
R4474 T15603 T15600 compound amino,acids
R4475 T15604 T15600 prep of,acids
R4476 T15605 T15606 det the,protein
R4477 T15606 T15604 pobj protein,of
R4478 T15607 T15606 compound FOG2,protein
R4479 T15608 T15567 punct .,incorporated
R4480 T15610 T15611 det The,module
R4481 T15611 T15615 nsubjpass module,followed
R4482 T15612 T15613 compound Fog2,lacZ
R4483 T15613 T15611 compound lacZ,module
R4484 T15614 T15613 punct -,lacZ
R4485 T15616 T15615 auxpass is,followed
R4486 T15617 T15615 agent by,followed
R4487 T15618 T15619 det an,cassette
R4488 T15619 T15617 pobj cassette,by
R4489 T15620 T15621 compound ires,eGFP
R4490 T15621 T15619 compound eGFP,cassette
R4491 T15622 T15621 punct -,eGFP
R4492 T15623 T15615 punct .,followed
R4493 T15625 T15626 nsubj This,creates
R4494 T15627 T15628 det a,allele
R4495 T15628 T15626 dobj allele,creates
R4496 T15629 T15628 amod null,allele
R4497 T15630 T15628 prep of,allele
R4498 T15631 T15632 compound Fog2,gene
R4499 T15632 T15630 pobj gene,of
R4500 T15633 T15626 punct .,creates
R4501 T15635 T15636 det The,construct
R4502 T15636 T15642 nsubjpass construct,linearized
R4503 T15637 T15638 compound Fog2,eGFP
R4504 T15638 T15636 compound eGFP,construct
R4505 T15639 T15638 punct -,eGFP
R4506 T15640 T15638 compound LacZ,eGFP
R4507 T15641 T15638 punct -,eGFP
R4508 T15643 T15642 auxpass was,linearized
R4509 T15644 T15642 prep with,linearized
R4510 T15645 T15644 pobj KspI,with
R4511 T15646 T15642 cc and,linearized
R4512 T15647 T15642 conj electroporated,linearized
R4513 T15648 T15647 prep into,electroporated
R4514 T15649 T15650 det the,cells
R4515 T15650 T15648 pobj cells,into
R4516 T15651 T15650 compound CJ7,cells
R4517 T15652 T15650 compound ES,cells
R4518 T15653 T15642 punct .,linearized
R4519 T15655 T15656 det The,clone
R4520 T15656 T15659 nsubjpass clone,selected
R4521 T15657 T15658 advmod correctly,targeted
R4522 T15658 T15656 amod targeted,clone
R4523 T15660 T15659 auxpass was,selected
R4524 T15661 T15659 prep by,selected
R4525 T15662 T15663 det the,analysis
R4526 T15663 T15661 pobj analysis,by
R4527 T15664 T15665 compound Southern,blot
R4528 T15665 T15663 compound blot,analysis
R4529 T15666 T15659 cc and,selected
R4530 T15667 T15659 conj injected,selected
R4531 T15668 T15667 prep into,injected
R4532 T15669 T15670 compound C57BL,6J
R4533 T15670 T15672 compound 6J,blastocysts
R4534 T15671 T15670 punct /,6J
R4535 T15672 T15668 pobj blastocysts,into
R4536 T15673 T15659 punct .,selected
R4537 T15675 T15676 compound Fog2,eGFP
R4538 T15676 T15680 compound eGFP,animals
R4539 T15677 T15676 punct -,eGFP
R4540 T15678 T15676 compound lacZ,eGFP
R4541 T15679 T15676 punct -,eGFP
R4542 T15680 T15681 nsubjpass animals,maintained
R4543 T15682 T15681 auxpass were,maintained
R4544 T15683 T15681 prep on,maintained
R4545 T15684 T15685 det the,background
R4546 T15685 T15683 pobj background,on
R4547 T15686 T15685 amod mixed,background
R4548 T15687 T15688 nmod C57BL,6J
R4549 T15688 T15685 nmod 6J,background
R4550 T15689 T15688 punct /,6J
R4551 T15690 T15688 punct /,6J
R4552 T15691 T15688 nummod 129,6J
R4553 T15692 T15681 punct .,maintained
R4554 T15694 T15695 compound lacZ,Expression
R4555 T15695 T15696 nsubjpass Expression,analyzed
R4556 T15697 T15695 prep in,Expression
R4557 T15698 T15699 amod whole,lungs
R4558 T15699 T15697 pobj lungs,in
R4559 T15700 T15699 amod dissected,lungs
R4560 T15701 T15699 amod embryonic,lungs
R4561 T15702 T15696 auxpass was,analyzed
R4562 T15703 T15696 prep by,analyzed
R4563 T15704 T15703 pcomp staining,by
R4564 T15705 T15704 prep for,staining
R4565 T15706 T15707 compound β,galactosidase
R4566 T15707 T15709 compound galactosidase,activity
R4567 T15708 T15707 punct -,galactosidase
R4568 T15709 T15705 pobj activity,for
R4569 T15710 T15704 prep with,staining
R4570 T15711 T15712 compound X,gal
R4571 T15712 T15710 pobj gal,with
R4572 T15713 T15712 punct -,gal
R4573 T15714 T15704 prep after,staining
R4574 T15715 T15714 pobj fixation,after
R4575 T15716 T15715 prep for,fixation
R4576 T15717 T15718 nummod 30,min
R4577 T15718 T15716 pobj min,for
R4578 T15719 T15696 punct .,analyzed