Id |
Subject |
Object |
Predicate |
Lexical cue |
T13230 |
0-8 |
JJ |
denotes |
Numerous |
T13231 |
20-33 |
NNS |
denotes |
abnormalities |
T13232 |
9-19 |
NN |
denotes |
chromosome |
T13233 |
44-49 |
VBN |
denotes |
found |
T13234 |
34-38 |
VBP |
denotes |
have |
T13235 |
39-43 |
VBN |
denotes |
been |
T13236 |
50-52 |
IN |
denotes |
in |
T13237 |
53-64 |
NN |
denotes |
association |
T13238 |
65-69 |
IN |
denotes |
with |
T13239 |
70-80 |
JJ |
denotes |
congenital |
T13240 |
91-104 |
NNS |
denotes |
abnormalities |
T13241 |
81-90 |
NN |
denotes |
diaphragm |
T13242 |
105-106 |
-LRB- |
denotes |
[ |
T13243 |
109-111 |
CD |
denotes |
35 |
T13244 |
106-108 |
CD |
denotes |
12 |
T13245 |
108-109 |
, |
denotes |
, |
T13246 |
111-112 |
-RRB- |
denotes |
] |
T13247 |
112-113 |
. |
denotes |
. |
T13248 |
113-269 |
sentence |
denotes |
Human FOG2 maps to Chromosome 8q23.1, and, importantly, several patients with diaphragm defects and rearrangements involving this locus have been reported. |
T13249 |
114-119 |
JJ |
denotes |
Human |
T13250 |
120-124 |
NN |
denotes |
FOG2 |
T13251 |
125-129 |
VBZ |
denotes |
maps |
T13252 |
130-132 |
IN |
denotes |
to |
T13253 |
133-143 |
NN |
denotes |
Chromosome |
T13254 |
144-150 |
CD |
denotes |
8q23.1 |
T13255 |
150-152 |
, |
denotes |
, |
T13256 |
152-155 |
CC |
denotes |
and |
T13257 |
155-157 |
, |
denotes |
, |
T13258 |
157-168 |
RB |
denotes |
importantly |
T13259 |
260-268 |
VBN |
denotes |
reported |
T13260 |
168-170 |
, |
denotes |
, |
T13261 |
170-177 |
JJ |
denotes |
several |
T13262 |
178-186 |
NNS |
denotes |
patients |
T13263 |
187-191 |
IN |
denotes |
with |
T13264 |
192-201 |
NN |
denotes |
diaphragm |
T13265 |
202-209 |
NNS |
denotes |
defects |
T13266 |
210-213 |
CC |
denotes |
and |
T13267 |
214-228 |
NNS |
denotes |
rearrangements |
T13268 |
229-238 |
VBG |
denotes |
involving |
T13269 |
239-243 |
DT |
denotes |
this |
T13270 |
244-249 |
NN |
denotes |
locus |
T13271 |
250-254 |
VBP |
denotes |
have |
T13272 |
255-259 |
VBN |
denotes |
been |
T13273 |
268-269 |
. |
denotes |
. |
T13274 |
269-402 |
sentence |
denotes |
Specifically, there are three unrelated CDH patients with cytogenetically balanced translocations at or near the FOG2 locus [36,37]. |
T13275 |
270-282 |
RB |
denotes |
Specifically |
T13276 |
290-293 |
VBP |
denotes |
are |
T13277 |
282-284 |
, |
denotes |
, |
T13278 |
284-289 |
EX |
denotes |
there |
T13279 |
294-299 |
CD |
denotes |
three |
T13280 |
314-322 |
NNS |
denotes |
patients |
T13281 |
300-309 |
JJ |
denotes |
unrelated |
T13282 |
310-313 |
NN |
denotes |
CDH |
T13283 |
323-327 |
IN |
denotes |
with |
T13284 |
328-343 |
RB |
denotes |
cytogenetically |
T13285 |
344-352 |
VBN |
denotes |
balanced |
T13286 |
353-367 |
NNS |
denotes |
translocations |
T13287 |
368-370 |
IN |
denotes |
at |
T13288 |
371-373 |
CC |
denotes |
or |
T13289 |
374-378 |
IN |
denotes |
near |
T13290 |
379-382 |
DT |
denotes |
the |
T13291 |
388-393 |
NN |
denotes |
locus |
T13292 |
383-387 |
NN |
denotes |
FOG2 |
T13293 |
394-395 |
-LRB- |
denotes |
[ |
T13294 |
398-400 |
CD |
denotes |
37 |
T13295 |
395-397 |
CD |
denotes |
36 |
T13296 |
397-398 |
, |
denotes |
, |
T13297 |
400-401 |
-RRB- |
denotes |
] |
T13298 |
401-402 |
. |
denotes |
. |
T13299 |
402-551 |
sentence |
denotes |
Additionally, two patients with deletions apparently encompassing the FOG2 locus have died from multiple congenital anomalies including CDH [38–40]. |
T13300 |
403-415 |
RB |
denotes |
Additionally |
T13301 |
489-493 |
VBN |
denotes |
died |
T13302 |
415-417 |
, |
denotes |
, |
T13303 |
417-420 |
CD |
denotes |
two |
T13304 |
421-429 |
NNS |
denotes |
patients |
T13305 |
430-434 |
IN |
denotes |
with |
T13306 |
435-444 |
NNS |
denotes |
deletions |
T13307 |
445-455 |
RB |
denotes |
apparently |
T13308 |
456-468 |
VBG |
denotes |
encompassing |
T13309 |
469-472 |
DT |
denotes |
the |
T13310 |
478-483 |
NN |
denotes |
locus |
T13311 |
473-477 |
NN |
denotes |
FOG2 |
T13312 |
484-488 |
VBP |
denotes |
have |
T13313 |
494-498 |
IN |
denotes |
from |
T13314 |
499-507 |
JJ |
denotes |
multiple |
T13315 |
519-528 |
NNS |
denotes |
anomalies |
T13316 |
508-518 |
JJ |
denotes |
congenital |
T13317 |
529-538 |
VBG |
denotes |
including |
T13318 |
539-542 |
NN |
denotes |
CDH |
T13319 |
543-544 |
-LRB- |
denotes |
[ |
T13320 |
544-546 |
CD |
denotes |
38 |
T13321 |
546-547 |
SYM |
denotes |
– |
T13322 |
547-549 |
CD |
denotes |
40 |
T13323 |
549-550 |
-RRB- |
denotes |
] |
T13324 |
550-551 |
. |
denotes |
. |
T13325 |
551-715 |
sentence |
denotes |
Inactivation of this gene due to chromosomal rearrangement or deletion would result in a heterozygous null mutation similar to that found in the patient we report. |
T13326 |
552-564 |
NN |
denotes |
Inactivation |
T13327 |
629-635 |
VB |
denotes |
result |
T13328 |
565-567 |
IN |
denotes |
of |
T13329 |
568-572 |
DT |
denotes |
this |
T13330 |
573-577 |
NN |
denotes |
gene |
T13331 |
578-581 |
IN |
denotes |
due |
T13332 |
582-584 |
IN |
denotes |
to |
T13333 |
585-596 |
JJ |
denotes |
chromosomal |
T13334 |
597-610 |
NN |
denotes |
rearrangement |
T13335 |
611-613 |
CC |
denotes |
or |
T13336 |
614-622 |
NN |
denotes |
deletion |
T13337 |
623-628 |
MD |
denotes |
would |
T13338 |
636-638 |
IN |
denotes |
in |
T13339 |
639-640 |
DT |
denotes |
a |
T13340 |
659-667 |
NN |
denotes |
mutation |
T13341 |
641-653 |
JJ |
denotes |
heterozygous |
T13342 |
654-658 |
JJ |
denotes |
null |
T13343 |
668-675 |
JJ |
denotes |
similar |
T13344 |
676-678 |
IN |
denotes |
to |
T13345 |
679-683 |
DT |
denotes |
that |
T13346 |
684-689 |
VBN |
denotes |
found |
T13347 |
690-692 |
IN |
denotes |
in |
T13348 |
693-696 |
DT |
denotes |
the |
T13349 |
697-704 |
NN |
denotes |
patient |
T13350 |
705-707 |
PRP |
denotes |
we |
T13351 |
708-714 |
VBP |
denotes |
report |
T13352 |
714-715 |
. |
denotes |
. |
R3189 |
T13230 |
T13231 |
amod |
Numerous,abnormalities |
R3190 |
T13231 |
T13233 |
nsubjpass |
abnormalities,found |
R3191 |
T13232 |
T13231 |
compound |
chromosome,abnormalities |
R3192 |
T13234 |
T13233 |
aux |
have,found |
R3193 |
T13235 |
T13233 |
auxpass |
been,found |
R3194 |
T13236 |
T13233 |
prep |
in,found |
R3195 |
T13237 |
T13236 |
pobj |
association,in |
R3196 |
T13238 |
T13237 |
prep |
with,association |
R3197 |
T13239 |
T13240 |
amod |
congenital,abnormalities |
R3198 |
T13240 |
T13238 |
pobj |
abnormalities,with |
R3199 |
T13241 |
T13240 |
compound |
diaphragm,abnormalities |
R3200 |
T13242 |
T13243 |
punct |
[,35 |
R3201 |
T13243 |
T13233 |
parataxis |
35,found |
R3202 |
T13244 |
T13243 |
nummod |
12,35 |
R3203 |
T13245 |
T13243 |
punct |
",",35 |
R3204 |
T13246 |
T13243 |
punct |
],35 |
R3205 |
T13247 |
T13233 |
punct |
.,found |
R3206 |
T13249 |
T13250 |
amod |
Human,FOG2 |
R3207 |
T13250 |
T13251 |
nsubj |
FOG2,maps |
R3208 |
T13252 |
T13251 |
prep |
to,maps |
R3209 |
T13253 |
T13252 |
pobj |
Chromosome,to |
R3210 |
T13254 |
T13253 |
nummod |
8q23.1,Chromosome |
R3211 |
T13255 |
T13251 |
punct |
", ",maps |
R3212 |
T13256 |
T13251 |
cc |
and,maps |
R3213 |
T13257 |
T13251 |
punct |
", ",maps |
R3214 |
T13258 |
T13259 |
advmod |
importantly,reported |
R3215 |
T13259 |
T13251 |
conj |
reported,maps |
R3216 |
T13260 |
T13259 |
punct |
", ",reported |
R3217 |
T13261 |
T13262 |
amod |
several,patients |
R3218 |
T13262 |
T13259 |
nsubjpass |
patients,reported |
R3219 |
T13263 |
T13262 |
prep |
with,patients |
R3220 |
T13264 |
T13265 |
compound |
diaphragm,defects |
R3221 |
T13265 |
T13263 |
pobj |
defects,with |
R3222 |
T13266 |
T13265 |
cc |
and,defects |
R3223 |
T13267 |
T13265 |
conj |
rearrangements,defects |
R3224 |
T13268 |
T13267 |
acl |
involving,rearrangements |
R3225 |
T13269 |
T13270 |
det |
this,locus |
R3226 |
T13270 |
T13268 |
dobj |
locus,involving |
R3227 |
T13271 |
T13259 |
aux |
have,reported |
R3228 |
T13272 |
T13259 |
auxpass |
been,reported |
R3229 |
T13273 |
T13259 |
punct |
.,reported |
R3230 |
T13275 |
T13276 |
advmod |
Specifically,are |
R3231 |
T13277 |
T13276 |
punct |
", ",are |
R3232 |
T13278 |
T13276 |
expl |
there,are |
R3233 |
T13279 |
T13280 |
nummod |
three,patients |
R3234 |
T13280 |
T13276 |
attr |
patients,are |
R3235 |
T13281 |
T13280 |
amod |
unrelated,patients |
R3236 |
T13282 |
T13280 |
compound |
CDH,patients |
R3237 |
T13283 |
T13280 |
prep |
with,patients |
R3238 |
T13284 |
T13285 |
advmod |
cytogenetically,balanced |
R3239 |
T13285 |
T13286 |
amod |
balanced,translocations |
R3240 |
T13286 |
T13283 |
pobj |
translocations,with |
R3241 |
T13287 |
T13286 |
prep |
at,translocations |
R3242 |
T13288 |
T13287 |
cc |
or,at |
R3243 |
T13289 |
T13287 |
conj |
near,at |
R3244 |
T13290 |
T13291 |
det |
the,locus |
R3245 |
T13291 |
T13289 |
pobj |
locus,near |
R3246 |
T13292 |
T13291 |
compound |
FOG2,locus |
R3247 |
T13293 |
T13294 |
punct |
[,37 |
R3248 |
T13294 |
T13276 |
parataxis |
37,are |
R3249 |
T13295 |
T13294 |
nummod |
36,37 |
R3250 |
T13296 |
T13294 |
punct |
",",37 |
R3251 |
T13297 |
T13294 |
punct |
],37 |
R3252 |
T13298 |
T13276 |
punct |
.,are |
R3253 |
T13300 |
T13301 |
advmod |
Additionally,died |
R3254 |
T13302 |
T13301 |
punct |
", ",died |
R3255 |
T13303 |
T13304 |
nummod |
two,patients |
R3256 |
T13304 |
T13301 |
nsubj |
patients,died |
R3257 |
T13305 |
T13304 |
prep |
with,patients |
R3258 |
T13306 |
T13305 |
pobj |
deletions,with |
R3259 |
T13307 |
T13308 |
advmod |
apparently,encompassing |
R3260 |
T13308 |
T13306 |
acl |
encompassing,deletions |
R3261 |
T13309 |
T13310 |
det |
the,locus |
R3262 |
T13310 |
T13308 |
dobj |
locus,encompassing |
R3263 |
T13311 |
T13310 |
compound |
FOG2,locus |
R3264 |
T13312 |
T13301 |
aux |
have,died |
R3265 |
T13313 |
T13301 |
prep |
from,died |
R3266 |
T13314 |
T13315 |
amod |
multiple,anomalies |
R3267 |
T13315 |
T13313 |
pobj |
anomalies,from |
R3268 |
T13316 |
T13315 |
amod |
congenital,anomalies |
R3269 |
T13317 |
T13315 |
prep |
including,anomalies |
R3270 |
T13318 |
T13317 |
pobj |
CDH,including |
R3271 |
T13319 |
T13320 |
punct |
[,38 |
R3272 |
T13320 |
T13301 |
parataxis |
38,died |
R3273 |
T13321 |
T13322 |
punct |
–,40 |
R3274 |
T13322 |
T13320 |
prep |
40,38 |
R3275 |
T13323 |
T13320 |
punct |
],38 |
R3276 |
T13324 |
T13301 |
punct |
.,died |
R3277 |
T13326 |
T13327 |
nsubj |
Inactivation,result |
R3278 |
T13328 |
T13326 |
prep |
of,Inactivation |
R3279 |
T13329 |
T13330 |
det |
this,gene |
R3280 |
T13330 |
T13328 |
pobj |
gene,of |
R3281 |
T13331 |
T13326 |
prep |
due,Inactivation |
R3282 |
T13332 |
T13331 |
pcomp |
to,due |
R3283 |
T13333 |
T13334 |
amod |
chromosomal,rearrangement |
R3284 |
T13334 |
T13331 |
pobj |
rearrangement,due |
R3285 |
T13335 |
T13334 |
cc |
or,rearrangement |
R3286 |
T13336 |
T13334 |
conj |
deletion,rearrangement |
R3287 |
T13337 |
T13327 |
aux |
would,result |
R3288 |
T13338 |
T13327 |
prep |
in,result |
R3289 |
T13339 |
T13340 |
det |
a,mutation |
R3290 |
T13340 |
T13338 |
pobj |
mutation,in |
R3291 |
T13341 |
T13340 |
amod |
heterozygous,mutation |
R3292 |
T13342 |
T13340 |
amod |
null,mutation |
R3293 |
T13343 |
T13340 |
amod |
similar,mutation |
R3294 |
T13344 |
T13343 |
prep |
to,similar |
R3295 |
T13345 |
T13344 |
pobj |
that,to |
R3296 |
T13346 |
T13345 |
acl |
found,that |
R3297 |
T13347 |
T13346 |
prep |
in,found |
R3298 |
T13348 |
T13349 |
det |
the,patient |
R3299 |
T13349 |
T13347 |
pobj |
patient,in |
R3300 |
T13350 |
T13351 |
nsubj |
we,report |
R3301 |
T13351 |
T13349 |
advcl |
report,patient |
R3302 |
T13352 |
T13327 |
punct |
.,result |