Id |
Subject |
Object |
Predicate |
Lexical cue |
T242 |
0-2 |
PRP |
denotes |
We |
T243 |
3-7 |
VBD |
denotes |
used |
T244 |
8-13 |
JJ |
denotes |
brief |
T245 |
14-20 |
NN |
denotes |
access |
T246 |
13-14 |
HYPH |
denotes |
- |
T247 |
38-45 |
NN |
denotes |
testing |
T248 |
21-31 |
JJ |
denotes |
behavioral |
T249 |
32-37 |
NN |
denotes |
taste |
T250 |
46-48 |
IN |
denotes |
of |
T251 |
49-52 |
NN |
denotes |
BXD |
T252 |
53-55 |
NN |
denotes |
Ty |
T253 |
52-53 |
HYPH |
denotes |
/ |
T254 |
86-93 |
NNS |
denotes |
strains |
T255 |
56-67 |
JJ |
denotes |
recombinant |
T256 |
68-74 |
JJ |
denotes |
inbred |
T257 |
75-76 |
-LRB- |
denotes |
( |
T258 |
76-78 |
JJ |
denotes |
RI |
T259 |
78-79 |
-RRB- |
denotes |
) |
T260 |
80-85 |
NN |
denotes |
mouse |
T261 |
94-96 |
TO |
denotes |
to |
T262 |
97-100 |
VB |
denotes |
map |
T263 |
101-104 |
DT |
denotes |
the |
T264 |
130-135 |
NN |
denotes |
locus |
T265 |
105-110 |
JJ |
denotes |
major |
T266 |
111-123 |
JJ |
denotes |
quantitative |
T267 |
124-129 |
NN |
denotes |
trait |
T268 |
136-137 |
-LRB- |
denotes |
( |
T269 |
137-140 |
NN |
denotes |
QTL |
T270 |
140-141 |
-RRB- |
denotes |
) |
T271 |
142-145 |
IN |
denotes |
for |
T272 |
146-151 |
NN |
denotes |
taste |
T273 |
152-163 |
NN |
denotes |
sensitivity |
T274 |
164-166 |
IN |
denotes |
to |
T275 |
167-171 |
NN |
denotes |
QHCl |
T276 |
171-172 |
. |
denotes |
. |
T277 |
172-278 |
sentence |
denotes |
This QTL is restricted to a ~5 Mb interval on chromosome 6 that includes 24 genes encoding T2Rs (Tas2rs). |
T278 |
173-177 |
DT |
denotes |
This |
T279 |
178-181 |
NN |
denotes |
QTL |
T280 |
185-195 |
VBN |
denotes |
restricted |
T281 |
182-184 |
VBZ |
denotes |
is |
T282 |
196-198 |
IN |
denotes |
to |
T283 |
199-200 |
DT |
denotes |
a |
T284 |
207-215 |
NN |
denotes |
interval |
T285 |
201-202 |
SYM |
denotes |
~ |
T286 |
202-203 |
CD |
denotes |
5 |
T287 |
204-206 |
NN |
denotes |
Mb |
T288 |
216-218 |
IN |
denotes |
on |
T289 |
219-229 |
NN |
denotes |
chromosome |
T290 |
230-231 |
CD |
denotes |
6 |
T291 |
232-236 |
WDT |
denotes |
that |
T292 |
237-245 |
VBZ |
denotes |
includes |
T293 |
246-248 |
CD |
denotes |
24 |
T294 |
249-254 |
NNS |
denotes |
genes |
T295 |
255-263 |
VBG |
denotes |
encoding |
T296 |
264-268 |
NNS |
denotes |
T2Rs |
T297 |
269-270 |
-LRB- |
denotes |
( |
T298 |
270-276 |
NNS |
denotes |
Tas2rs |
T299 |
276-277 |
-RRB- |
denotes |
) |
T300 |
277-278 |
. |
denotes |
. |
T301 |
278-529 |
sentence |
denotes |
Tas2rs at this locus display in total 307 coding region single nucleotide polymorphisms (SNPs) between the two BXD/Ty RI parental strains, C57BL/6J (quinine-sensitive) and DBA/2J (quinine insensitive); approximately 50% of these mutations are silent. |
T302 |
279-285 |
NNS |
denotes |
Tas2rs |
T303 |
300-307 |
VBP |
denotes |
display |
T304 |
286-288 |
IN |
denotes |
at |
T305 |
289-293 |
DT |
denotes |
this |
T306 |
294-299 |
NN |
denotes |
locus |
T307 |
518-521 |
VBP |
denotes |
are |
T308 |
308-310 |
IN |
denotes |
in |
T309 |
311-316 |
JJ |
denotes |
total |
T310 |
317-320 |
CD |
denotes |
307 |
T311 |
353-366 |
NNS |
denotes |
polymorphisms |
T312 |
321-327 |
NN |
denotes |
coding |
T313 |
328-334 |
NN |
denotes |
region |
T314 |
335-341 |
JJ |
denotes |
single |
T315 |
342-352 |
NN |
denotes |
nucleotide |
T316 |
367-368 |
-LRB- |
denotes |
( |
T317 |
368-372 |
NNS |
denotes |
SNPs |
T318 |
372-373 |
-RRB- |
denotes |
) |
T319 |
374-381 |
IN |
denotes |
between |
T320 |
382-385 |
DT |
denotes |
the |
T321 |
409-416 |
NNS |
denotes |
strains |
T322 |
386-389 |
CD |
denotes |
two |
T323 |
390-393 |
NN |
denotes |
BXD |
T324 |
394-396 |
NN |
denotes |
Ty |
T325 |
393-394 |
HYPH |
denotes |
/ |
T326 |
397-399 |
JJ |
denotes |
RI |
T327 |
400-408 |
JJ |
denotes |
parental |
T328 |
416-418 |
, |
denotes |
, |
T329 |
418-423 |
NN |
denotes |
C57BL |
T330 |
424-426 |
NN |
denotes |
6J |
T331 |
423-424 |
HYPH |
denotes |
/ |
T332 |
427-428 |
-LRB- |
denotes |
( |
T333 |
436-445 |
JJ |
denotes |
sensitive |
T334 |
428-435 |
NN |
denotes |
quinine |
T335 |
435-436 |
HYPH |
denotes |
- |
T336 |
445-446 |
-RRB- |
denotes |
) |
T337 |
447-450 |
CC |
denotes |
and |
T338 |
451-454 |
NN |
denotes |
DBA |
T339 |
455-457 |
NN |
denotes |
2J |
T340 |
454-455 |
HYPH |
denotes |
/ |
T341 |
458-459 |
-LRB- |
denotes |
( |
T342 |
467-478 |
JJ |
denotes |
insensitive |
T343 |
459-466 |
NN |
denotes |
quinine |
T344 |
478-479 |
-RRB- |
denotes |
) |
T345 |
479-480 |
: |
denotes |
; |
T346 |
481-494 |
RB |
denotes |
approximately |
T347 |
495-497 |
CD |
denotes |
50 |
T348 |
497-498 |
NN |
denotes |
% |
T349 |
499-501 |
IN |
denotes |
of |
T350 |
502-507 |
DT |
denotes |
these |
T351 |
508-517 |
NNS |
denotes |
mutations |
T352 |
522-528 |
JJ |
denotes |
silent |
T353 |
528-529 |
. |
denotes |
. |
T354 |
529-740 |
sentence |
denotes |
Individual RI lines contain exclusively either C57BL/6J or DBA/2J Tas2r alleles at this locus, and RI lines containing C57BL/6J Tas2r alleles are more sensitive to QHCl than are lines containing DBA/2J alleles. |
T355 |
530-540 |
JJ |
denotes |
Individual |
T356 |
544-549 |
NNS |
denotes |
lines |
T357 |
541-543 |
JJ |
denotes |
RI |
T358 |
550-557 |
VBP |
denotes |
contain |
T359 |
558-569 |
RB |
denotes |
exclusively |
T360 |
570-576 |
CC |
denotes |
either |
T361 |
583-585 |
NN |
denotes |
6J |
T362 |
577-582 |
NN |
denotes |
C57BL |
T363 |
582-583 |
HYPH |
denotes |
/ |
T364 |
602-609 |
NNS |
denotes |
alleles |
T365 |
586-588 |
CC |
denotes |
or |
T366 |
589-592 |
NN |
denotes |
DBA |
T367 |
593-595 |
NN |
denotes |
2J |
T368 |
592-593 |
HYPH |
denotes |
/ |
T369 |
596-601 |
NN |
denotes |
Tas2r |
T370 |
610-612 |
IN |
denotes |
at |
T371 |
613-617 |
DT |
denotes |
this |
T372 |
618-623 |
NN |
denotes |
locus |
T373 |
623-625 |
, |
denotes |
, |
T374 |
625-628 |
CC |
denotes |
and |
T375 |
629-631 |
JJ |
denotes |
RI |
T376 |
632-637 |
NNS |
denotes |
lines |
T377 |
672-675 |
VBP |
denotes |
are |
T378 |
638-648 |
VBG |
denotes |
containing |
T379 |
649-654 |
NN |
denotes |
C57BL |
T380 |
655-657 |
NN |
denotes |
6J |
T381 |
654-655 |
HYPH |
denotes |
/ |
T382 |
664-671 |
NNS |
denotes |
alleles |
T383 |
658-663 |
NN |
denotes |
Tas2r |
T384 |
676-680 |
RBR |
denotes |
more |
T385 |
681-690 |
JJ |
denotes |
sensitive |
T386 |
691-693 |
IN |
denotes |
to |
T387 |
694-698 |
NN |
denotes |
QHCl |
T388 |
699-703 |
IN |
denotes |
than |
T389 |
704-707 |
VBP |
denotes |
are |
T390 |
708-713 |
NNS |
denotes |
lines |
T391 |
714-724 |
VBG |
denotes |
containing |
T392 |
725-728 |
NN |
denotes |
DBA |
T393 |
729-731 |
NN |
denotes |
2J |
T394 |
728-729 |
HYPH |
denotes |
/ |
T395 |
732-739 |
NNS |
denotes |
alleles |
T396 |
739-740 |
. |
denotes |
. |
T397 |
740-843 |
sentence |
denotes |
Thus, the entire Tas2r cluster comprises a large haplotype that correlates with quinine taster status. |
T398 |
741-745 |
RB |
denotes |
Thus |
T399 |
772-781 |
VBZ |
denotes |
comprises |
T400 |
745-747 |
, |
denotes |
, |
T401 |
747-750 |
DT |
denotes |
the |
T402 |
764-771 |
NN |
denotes |
cluster |
T403 |
751-757 |
JJ |
denotes |
entire |
T404 |
758-763 |
NN |
denotes |
Tas2r |
T405 |
782-783 |
DT |
denotes |
a |
T406 |
790-799 |
NN |
denotes |
haplotype |
T407 |
784-789 |
JJ |
denotes |
large |
T408 |
800-804 |
WDT |
denotes |
that |
T409 |
805-815 |
VBZ |
denotes |
correlates |
T410 |
816-820 |
IN |
denotes |
with |
T411 |
821-828 |
NN |
denotes |
quinine |
T412 |
829-835 |
NN |
denotes |
taster |
T413 |
836-842 |
NN |
denotes |
status |
T414 |
842-843 |
. |
denotes |
. |
R103 |
T242 |
T243 |
nsubj |
We,used |
R104 |
T244 |
T245 |
amod |
brief,access |
R105 |
T245 |
T247 |
nmod |
access,testing |
R107 |
T247 |
T243 |
dobj |
testing,used |
R110 |
T250 |
T247 |
prep |
of,testing |
R111 |
T251 |
T252 |
nmod |
BXD,Ty |
R112 |
T252 |
T254 |
nmod |
Ty,strains |
R114 |
T254 |
T250 |
pobj |
strains,of |
R121 |
T261 |
T262 |
aux |
to,map |
R122 |
T262 |
T243 |
advcl |
map,used |
R123 |
T263 |
T264 |
det |
the,locus |
R124 |
T264 |
T262 |
dobj |
locus,map |
R128 |
T268 |
T264 |
punct |
(,locus |
R129 |
T269 |
T264 |
appos |
QTL,locus |
R130 |
T270 |
T262 |
punct |
),map |
R131 |
T271 |
T262 |
prep |
for,map |
R132 |
T272 |
T273 |
compound |
taste,sensitivity |
R133 |
T273 |
T271 |
pobj |
sensitivity,for |
R134 |
T274 |
T273 |
prep |
to,sensitivity |
R135 |
T275 |
T274 |
pobj |
QHCl,to |
R136 |
T276 |
T243 |
punct |
.,used |
R137 |
T278 |
T279 |
det |
This,QTL |
R138 |
T279 |
T280 |
nsubjpass |
QTL,restricted |
R139 |
T281 |
T280 |
auxpass |
is,restricted |
R140 |
T282 |
T280 |
prep |
to,restricted |
R141 |
T283 |
T284 |
det |
a,interval |
R142 |
T284 |
T282 |
pobj |
interval,to |
R146 |
T288 |
T284 |
prep |
on,interval |
R147 |
T289 |
T288 |
pobj |
chromosome,on |
R148 |
T290 |
T289 |
nummod |
6,chromosome |
R149 |
T291 |
T292 |
dep |
that,includes |
R150 |
T292 |
T284 |
relcl |
includes,interval |
R151 |
T293 |
T294 |
nummod |
24,genes |
R152 |
T294 |
T292 |
dobj |
genes,includes |
R153 |
T295 |
T294 |
acl |
encoding,genes |
R154 |
T296 |
T295 |
dobj |
T2Rs,encoding |
R155 |
T297 |
T296 |
punct |
(,T2Rs |
R156 |
T298 |
T296 |
appos |
Tas2rs,T2Rs |
R157 |
T299 |
T280 |
punct |
),restricted |
R158 |
T300 |
T280 |
punct |
.,restricted |
R159 |
T302 |
T303 |
nsubj |
Tas2rs,display |
R160 |
T303 |
T307 |
ccomp |
display,are |
R164 |
T308 |
T303 |
prep |
in,display |
R165 |
T309 |
T308 |
amod |
total,in |
R166 |
T310 |
T311 |
nummod |
307,polymorphisms |
R167 |
T311 |
T303 |
dobj |
polymorphisms,display |
R172 |
T316 |
T311 |
punct |
(,polymorphisms |
R173 |
T317 |
T311 |
appos |
SNPs,polymorphisms |
R174 |
T318 |
T311 |
punct |
),polymorphisms |
R175 |
T319 |
T311 |
prep |
between,polymorphisms |
R176 |
T320 |
T321 |
det |
the,strains |
R177 |
T321 |
T319 |
pobj |
strains,between |
R180 |
T324 |
T321 |
nmod |
Ty,strains |
R181 |
T325 |
T324 |
punct |
/,Ty |
R184 |
T328 |
T321 |
punct |
", ",strains |
R185 |
T329 |
T330 |
compound |
C57BL,6J |
R186 |
T330 |
T321 |
conj |
6J,strains |
R188 |
T332 |
T333 |
punct |
(,sensitive |
R189 |
T333 |
T330 |
parataxis |
sensitive,6J |
R192 |
T336 |
T333 |
punct |
),sensitive |
R193 |
T337 |
T330 |
cc |
and,6J |
R194 |
T338 |
T339 |
compound |
DBA,2J |
R195 |
T339 |
T330 |
conj |
2J,6J |
R197 |
T341 |
T342 |
punct |
(,insensitive |
R198 |
T342 |
T339 |
parataxis |
insensitive,2J |
R200 |
T344 |
T342 |
punct |
),insensitive |
R201 |
T345 |
T307 |
punct |
;,are |
R202 |
T346 |
T347 |
advmod |
approximately,50 |
R203 |
T347 |
T348 |
nummod |
50,% |
R204 |
T348 |
T307 |
nsubj |
%,are |
R205 |
T349 |
T348 |
prep |
of,% |
R206 |
T350 |
T351 |
det |
these,mutations |
R207 |
T351 |
T349 |
pobj |
mutations,of |
R208 |
T352 |
T307 |
acomp |
silent,are |
R209 |
T353 |
T307 |
punct |
.,are |
R210 |
T355 |
T356 |
amod |
Individual,lines |
R211 |
T356 |
T358 |
nsubj |
lines,contain |
R213 |
T359 |
T358 |
advmod |
exclusively,contain |
R214 |
T360 |
T361 |
preconj |
either,6J |
R215 |
T361 |
T364 |
nmod |
6J,alleles |
R218 |
T364 |
T358 |
dobj |
alleles,contain |
R221 |
T367 |
T361 |
conj |
2J,6J |
R222 |
T368 |
T367 |
punct |
/,2J |
R224 |
T370 |
T358 |
prep |
at,contain |
R225 |
T371 |
T372 |
det |
this,locus |
R226 |
T372 |
T370 |
pobj |
locus,at |
R227 |
T373 |
T358 |
punct |
", ",contain |
R228 |
T374 |
T358 |
cc |
and,contain |
R229 |
T375 |
T376 |
amod |
RI,lines |
R230 |
T376 |
T377 |
nsubj |
lines,are |
R231 |
T377 |
T358 |
conj |
are,contain |
R234 |
T380 |
T382 |
compound |
6J,alleles |
R235 |
T381 |
T380 |
punct |
/,6J |
R236 |
T382 |
T378 |
dobj |
alleles,containing |
R237 |
T383 |
T382 |
compound |
Tas2r,alleles |
R238 |
T384 |
T385 |
advmod |
more,sensitive |
R239 |
T385 |
T377 |
acomp |
sensitive,are |
R240 |
T386 |
T385 |
prep |
to,sensitive |
R241 |
T387 |
T386 |
pobj |
QHCl,to |
R242 |
T388 |
T389 |
mark |
than,are |
R243 |
T389 |
T385 |
advcl |
are,sensitive |
R244 |
T390 |
T389 |
nsubj |
lines,are |
R245 |
T391 |
T390 |
acl |
containing,lines |
R246 |
T392 |
T393 |
compound |
DBA,2J |
R247 |
T393 |
T395 |
compound |
2J,alleles |
R249 |
T395 |
T391 |
dobj |
alleles,containing |
R250 |
T396 |
T377 |
punct |
.,are |
R251 |
T398 |
T399 |
advmod |
Thus,comprises |
R252 |
T400 |
T399 |
punct |
", ",comprises |
R253 |
T401 |
T402 |
det |
the,cluster |
R254 |
T402 |
T399 |
nsubj |
cluster,comprises |
R257 |
T405 |
T406 |
det |
a,haplotype |
R258 |
T406 |
T399 |
dobj |
haplotype,comprises |
R260 |
T408 |
T409 |
dep |
that,correlates |
R261 |
T409 |
T406 |
relcl |
correlates,haplotype |
R262 |
T410 |
T409 |
prep |
with,correlates |
R263 |
T411 |
T412 |
compound |
quinine,taster |
R264 |
T412 |
T413 |
compound |
taster,status |
R265 |
T413 |
T410 |
pobj |
status,with |
R266 |
T414 |
T399 |
punct |
.,comprises |
R106 |
T246 |
T245 |
punct |
-,access |
R108 |
T248 |
T247 |
amod |
behavioral,testing |
R109 |
T249 |
T247 |
compound |
taste,testing |
R113 |
T253 |
T252 |
punct |
/,Ty |
R115 |
T255 |
T256 |
amod |
recombinant,inbred |
R116 |
T256 |
T254 |
amod |
inbred,strains |
R117 |
T257 |
T258 |
punct |
(,RI |
R118 |
T258 |
T256 |
parataxis |
RI,inbred |
R119 |
T259 |
T258 |
punct |
),RI |
R120 |
T260 |
T254 |
compound |
mouse,strains |
R125 |
T265 |
T264 |
amod |
major,locus |
R126 |
T266 |
T264 |
amod |
quantitative,locus |
R127 |
T267 |
T264 |
compound |
trait,locus |
R143 |
T285 |
T286 |
punct |
~,5 |
R144 |
T286 |
T287 |
nummod |
5,Mb |
R145 |
T287 |
T284 |
compound |
Mb,interval |
R161 |
T304 |
T302 |
prep |
at,Tas2rs |
R162 |
T305 |
T306 |
det |
this,locus |
R163 |
T306 |
T304 |
pobj |
locus,at |
R168 |
T312 |
T311 |
nmod |
coding,polymorphisms |
R169 |
T313 |
T311 |
nmod |
region,polymorphisms |
R170 |
T314 |
T311 |
amod |
single,polymorphisms |
R171 |
T315 |
T311 |
compound |
nucleotide,polymorphisms |
R178 |
T322 |
T321 |
nummod |
two,strains |
R179 |
T323 |
T324 |
nmod |
BXD,Ty |
R182 |
T326 |
T321 |
amod |
RI,strains |
R183 |
T327 |
T321 |
amod |
parental,strains |
R187 |
T331 |
T330 |
punct |
/,6J |
R190 |
T334 |
T333 |
npadvmod |
quinine,sensitive |
R191 |
T335 |
T333 |
punct |
-,sensitive |
R196 |
T340 |
T339 |
punct |
/,2J |
R199 |
T343 |
T342 |
npadvmod |
quinine,insensitive |
R212 |
T357 |
T356 |
amod |
RI,lines |
R216 |
T362 |
T361 |
nmod |
C57BL,6J |
R217 |
T363 |
T361 |
punct |
/,6J |
R219 |
T365 |
T361 |
cc |
or,6J |
R220 |
T366 |
T367 |
compound |
DBA,2J |
R223 |
T369 |
T364 |
compound |
Tas2r,alleles |
R232 |
T378 |
T376 |
acl |
containing,lines |
R233 |
T379 |
T380 |
compound |
C57BL,6J |
R248 |
T394 |
T393 |
punct |
/,2J |
R255 |
T403 |
T402 |
amod |
entire,cluster |
R256 |
T404 |
T402 |
compound |
Tas2r,cluster |
R259 |
T407 |
T406 |
amod |
large,haplotype |