PMC:1181811 / 5625-19047 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T7341	13421-13422	.	denotes	.
T7340	13417-13421	NN	denotes	QHCL
T7339	13414-13416	NN	denotes	mM
T7338	13412-13413	CD	denotes	1
T7337	13409-13411	IN	denotes	to
T7336	13399-13408	JJ	denotes	sensitive
T7335	13394-13398	RBS	denotes	most
T7334	13391-13393	IN	denotes	to
T7333	13385-13390	RBS	denotes	least
T7332	13380-13384	IN	denotes	from
T7331	13374-13379	NN	denotes	order
T7330	13371-13373	IN	denotes	in
T7329	13360-13363	VBP	denotes	are
T7328	13364-13370	VBN	denotes	listed
T7327	13348-13351	NN	denotes	BXD
T7326	13352-13359	NNS	denotes	strains
T7325	13344-13347	DT	denotes	The
T7324	13343-13422	sentence	denotes	The BXD strains are listed in order from least to most sensitive to 1 mM QHCL.
T7323	13342-13343	.	denotes	.
T7322	13341-13342	-RRB-	denotes	)
T7321	13330-13335	JJ	denotes	right
T7320	13328-13330	,	denotes	,
T7319	13323-13328	NNS	denotes	lines
T7318	13319-13322	JJ	denotes	red
T7317	13336-13341	NN	denotes	panel
T7316	13318-13319	-LRB-	denotes	(
T7315	13302-13307	NN	denotes	Tas2r
T7314	13299-13301	NN	denotes	D2
T7313	13308-13317	NN	denotes	haplotype
T7312	13295-13298	DT	denotes	the
T7311	13290-13294	IN	denotes	with
T7310	13282-13289	NNS	denotes	strains
T7309	13278-13281	NN	denotes	BXD
T7308	13274-13277	VBP	denotes	are
T7307	13269-13273	IN	denotes	than
T7306	13264-13268	NN	denotes	QHCl
T7305	13261-13263	IN	denotes	to
T7304	13251-13260	JJ	denotes	sensitive
T7303	13246-13250	RBR	denotes	more
T7302	13240-13241	-RRB-	denotes	)
T7301	13229-13234	JJ	denotes	right
T7300	13227-13229	,	denotes	,
T7299	13222-13227	NNS	denotes	lines
T7298	13217-13221	JJ	denotes	blue
T7297	13235-13240	NN	denotes	panel
T7296	13216-13217	-LRB-	denotes	(
T7295	13200-13205	NN	denotes	Tas2r
T7294	13197-13199	NN	denotes	B6
T7293	13206-13215	NN	denotes	haplotype
T7292	13193-13196	DT	denotes	the
T7291	13188-13192	IN	denotes	with
T7290	13180-13187	NNS	denotes	strains
T7289	13176-13179	NN	denotes	BXD
T7288	13174-13176	,	denotes	,
T7287	13242-13245	VBP	denotes	are
T7286	13165-13174	RB	denotes	Similarly
T7285	13164-13343	sentence	denotes	Similarly, BXD strains with the B6 Tas2r haplotype (blue lines, right panel) are more sensitive to QHCl than are BXD strains with the D2 Tas2r haplotype (red lines, right panel).
T7284	13163-13164	.	denotes	.
T7283	13152-13157	NN	denotes	taste
T7282	13158-13163	NNS	denotes	tests
T7281	13145-13151	NN	denotes	access
T7280	13139-13144	JJ	denotes	brief
T7279	13136-13138	IN	denotes	in
T7278	13134-13135	-RRB-	denotes	)
T7277	13129-13134	NN	denotes	panel
T7276	13124-13128	JJ	denotes	left
T7275	13121-13123	IN	denotes	on
T7274	13112-13115	JJ	denotes	red
T7273	13116-13120	NN	denotes	line
T7272	13111-13112	-LRB-	denotes	(
T7271	13106-13110	NNS	denotes	mice
T7270	13103-13105	NN	denotes	D2
T7262	13075-13076	CD	denotes	1
T7261	13072-13074	IN	denotes	to
T7260	13062-13071	JJ	denotes	sensitive
T7259	13057-13061	RBR	denotes	more
T7258	13051-13052	-RRB-	denotes	)
T7257	13046-13051	NN	denotes	panel
T7256	13041-13045	JJ	denotes	left
T7255	13038-13040	IN	denotes	on
T7254	13028-13032	JJ	denotes	blue
T7253	13033-13037	NN	denotes	line
T7252	13027-13028	-LRB-	denotes	(
T7251	13053-13056	VBP	denotes	are
T7250	13022-13026	NNS	denotes	mice
T7249	13019-13021	NN	denotes	B6
T7248	13018-13164	sentence	denotes	B6 mice (blue line on left panel) are more sensitive to 1 mM and 3 mM QHCl than are D2 mice (red line on left panel) in brief access taste tests.
T7247	13017-13018	.	denotes	.
T7246	13016-13017	-RRB-	denotes	)
T7245	13011-13012	SYM	denotes	=
T7244	13001-13010	NN	denotes	haplotype
T7243	12998-13000	NN	denotes	D2
T7242	12996-12998	,	denotes	,
T7241	12990-12991	SYM	denotes	=
T7240	12992-12996	JJ	denotes	blue
T7239	12980-12989	NN	denotes	haplotype
T7238	12977-12979	NN	denotes	B6
T7237	13013-13016	JJ	denotes	red
T7236	12976-12977	-LRB-	denotes	(
T7235	12966-12975	NN	denotes	haplotype
T7234	12960-12965	NN	denotes	Tas2r
T7233	12957-12959	IN	denotes	on
T7232	12951-12956	VBN	denotes	based
T7231	12939-12942	VBP	denotes	are
T7230	12937-12938	CD	denotes	1
T7229	12930-12936	NN	denotes	Figure
T7228	12927-12929	IN	denotes	in
T7227	12918-12926	VBN	denotes	reported
T7226	12906-12909	NN	denotes	BXD
T7225	12902-12905	CC	denotes	and
T7224	12899-12901	NN	denotes	D2
T7223	12897-12899	,	denotes	,
T7222	12910-12917	NNS	denotes	strains
T7221	12895-12897	NN	denotes	B6
T7220	12892-12894	IN	denotes	of
T7219	12943-12950	VBN	denotes	grouped
T7218	12880-12884	NN	denotes	lick
T7217	12885-12891	NNS	denotes	ratios
T7216	12875-12879	NN	denotes	Mean
T7215	12874-13018	sentence	denotes	Mean lick ratios of B6, D2 and BXD strains reported in Figure 1 are grouped based on Tas2r haplotype (B6 haplotype = blue, D2 haplotype = red).
T7214	12873-12874	.	denotes	.
T7213	12864-12873	NN	denotes	phenotype
T7212	12858-12863	NN	denotes	taste
T7211	12853-12857	NN	denotes	QHCl
T7210	12848-12852	IN	denotes	with
T7209	12837-12847	VBZ	denotes	correlates
T7208	12828-12836	NN	denotes	genotype
T7207	12822-12827	NN	denotes	Tas2r
T7179	12810-12811	.	denotes	.
T7178	12809-12810	-RRB-	denotes	)
T7177	12808-12809	SYM	denotes	*
T7176	12807-12808	-LRB-	denotes	(
T7175	12793-12796	VBP	denotes	are
T7174	12787-12792	NN	denotes	study
T7173	12782-12786	DT	denotes	this
T7172	12779-12781	IN	denotes	in
T7171	12759-12771	RB	denotes	behaviorally
T7170	12754-12758	VBD	denotes	were
T7169	12772-12778	VBN	denotes	tested
T7168	12749-12753	WDT	denotes	that
T7167	12797-12806	VBN	denotes	indicated
T7166	12737-12740	NN	denotes	BXD
T7165	12734-12736	CD	denotes	17
T7164	12741-12748	NNS	denotes	strains
T7163	12730-12733	DT	denotes	The
T7162	12729-12811	sentence	denotes	The 17 BXD strains that were behaviorally tested in this study are indicated (*).
T7161	12728-12729	.	denotes	.
T7160	12727-12728	-RRB-	denotes	)
T7159	12720-12721	SYM	denotes	=
T7158	12713-12719	NN	denotes	allele
T7157	12710-12712	NN	denotes	D2
T7156	12708-12710	,	denotes	,
T7155	12702-12703	SYM	denotes	=
T7154	12704-12708	NN	denotes	gray
T7153	12695-12701	NN	denotes	allele
T7152	12692-12694	NN	denotes	B6
T7151	12722-12727	JJ	denotes	white
T7150	12691-12692	-LRB-	denotes	(
T7149	12675-12683	JJ	denotes	parental
T7148	12670-12674	JJ	denotes	same
T7147	12684-12690	NN	denotes	strain
T7146	12666-12669	DT	denotes	the
T7145	12661-12665	IN	denotes	from
T7144	12639-12642	NN	denotes	BXD
T7143	12628-12638	JJ	denotes	individual
T7142	12643-12649	NN	denotes	strain
T7141	12625-12627	DT	denotes	an
T7140	12618-12624	IN	denotes	within
T7139	12650-12660	VBD	denotes	originated
T7138	12612-12617	NN	denotes	Tas2r
T7137	12607-12611	DT	denotes	Each
T7136	12606-12729	sentence	denotes	Each Tas2r within an individual BXD strain originated from the same parental strain (B6 allele = gray, D2 allele = white).
T7135	12605-12606	.	denotes	.
T7134	12595-12597	JJ	denotes	RI
T7133	12591-12592	HYPH	denotes	/
T7132	12592-12594	NN	denotes	Ty
T7131	12588-12591	NN	denotes	BXD
T7130	12598-12605	NNS	denotes	strains
T7129	12585-12587	CD	denotes	29
T7128	12580-12584	IN	denotes	from
T7127	12568-12575	JJ	denotes	genomic
T7126	12576-12579	NN	denotes	DNA
T7125	12558-12567	VBN	denotes	amplified
T7124	12544-12545	CD	denotes	6
T7123	12533-12543	NN	denotes	chromosome
T7122	12526-12532	JJ	denotes	distal
T7121	12546-12553	NN	denotes	cluster
T7120	12522-12525	DT	denotes	the
T7119	12519-12521	IN	denotes	in
T7118	12512-12518	NNS	denotes	Tas2rs
T7117	12509-12511	CD	denotes	21
T7116	12506-12508	IN	denotes	of
T7115	12501-12505	DT	denotes	each
T7114	12498-12500	IN	denotes	of
T7113	12554-12557	VBD	denotes	was
T7112	12486-12492	VBG	denotes	coding
T7111	12493-12497	NN	denotes	exon
T7110	12482-12485	DT	denotes	The
T7109	12481-12606	sentence	denotes	The coding exon of each of 21 Tas2rs in the distal chromosome 6 cluster was amplified genomic DNA from 29 BXD/Ty RI strains.
T7108	12480-12481	.	denotes	.
T7107	12473-12475	JJ	denotes	RI
T7106	12476-12480	NNS	denotes	mice
T7105	12469-12470	HYPH	denotes	/
T7104	12470-12472	NN	denotes	Ty
T7103	12466-12469	NN	denotes	BXD
T7102	12463-12465	IN	denotes	in
T7101	12446-12452	JJ	denotes	single
T7100	12453-12462	NN	denotes	haplotype
T7099	12444-12445	DT	denotes	a
T7098	12441-12443	VBZ	denotes	is
T7097	12427-12432	NN	denotes	Tas2r
T7096	12433-12440	NN	denotes	cluster
T7095	12423-12426	DT	denotes	The
T7073	11042-11043	.	denotes	.
T7072	11026-11042	NNS	denotes	oligonucleotides
T7071	11022-11025	CC	denotes	and
T7070	11014-11021	NNS	denotes	enzymes
T7069	11002-11013	NN	denotes	restriction
T7068	10998-11001	IN	denotes	for
T7067	10996-10997	CD	denotes	3
T7066	10990-10995	NN	denotes	Table
T7065	10988-10990	:	denotes	:
T7064	10987-10988	CD	denotes	1
T7063	10982-10986	NN	denotes	file
T7062	10971-10981	JJ	denotes	additional
T7061	10967-10970	VB	denotes	See
T7060	10966-11043	sentence	denotes	See additional file 1: Table 3 for restriction enzymes and oligonucleotides.
T7059	10965-10966	.	denotes	.
T7058	10964-10965	-RRB-	denotes	)
T7057	10948-10954	NN	denotes	taster
T7056	10945-10947	NN	denotes	D2
T7055	10943-10944	SYM	denotes	=
T7054	10939-10942	NN	denotes	red
T7053	10937-10939	,	denotes	,
T7052	10921-10927	NN	denotes	taster
T7051	10918-10920	NN	denotes	B6
T7050	10916-10917	SYM	denotes	=
T7049	10928-10937	NN	denotes	phenotype
T7048	10911-10915	NN	denotes	blue
T7047	10955-10964	NN	denotes	phenotype
T6949	8235-8236	.	denotes	.
T6948	8226-8228	NN	denotes	B6
T6947	8229-8235	NN	denotes	genome
T6946	8222-8225	DT	denotes	the
T6945	8219-8221	IN	denotes	of
T6944	8205-8209	CD	denotes	2004
T6943	8203-8205	,	denotes	,
T6942	8200-8203	NN	denotes	May
T6941	8210-8218	NN	denotes	assembly
T6940	8196-8199	DT	denotes	the
T6939	8193-8195	IN	denotes	in
T6938	8181-8182	CD	denotes	6
T6937	8183-8192	NNS	denotes	positions
T6936	8170-8180	NN	denotes	chromosome
T6935	8158-8160	,	denotes	,
T6934	8156-8158	NN	denotes	Mb
T6933	8153-8155	IN	denotes	in
T6932	8151-8153	,	denotes	,
T6931	8160-8169	VBP	denotes	represent
T6930	8142-8151	NNS	denotes	positions
T6929	8138-8141	NN	denotes	Map
T6928	8137-8236	sentence	denotes	Map positions, in Mb, represent chromosome 6 positions in the May, 2004 assembly of the B6 genome.
T6927	8136-8137	.	denotes	.
T6926	8135-8136	-RRB-	denotes	)
T6925	8132-8135	JJ	denotes	red
T6924	8130-8131	:	denotes	;
T6923	8126-8130	NN	denotes	Prh1
T6922	8122-8125	CC	denotes	and
T6921	8117-8121	NN	denotes	Prp2
T6920	8116-8117	-LRB-	denotes	(
T6919	8098-8106	JJ	denotes	salivary
T6918	8107-8115	NN	denotes	proteins
T6917	8092-8093	HYPH	denotes	-
T6916	8093-8097	JJ	denotes	rich
T6915	8085-8092	NN	denotes	proline
T6914	8076-8084	VBG	denotes	encoding
T6913	8070-8075	NNS	denotes	genes
T6912	8066-8069	CD	denotes	two
T6911	8062-8065	CC	denotes	and
T6910	8060-8061	-RRB-	denotes	)
T6909	8057-8060	JJ	denotes	red
T6908	8056-8057	-LRB-	denotes	(
T6907	8041-8047	NN	denotes	marker
T6906	8029-8040	JJ	denotes	polymorphic
T6905	8048-8055	NN	denotes	D6Mit13
T6904	8025-8028	DT	denotes	the
T6903	8022-8024	IN	denotes	of
T6902	8017-8021	NN	denotes	side
T6901	8010-8016	DT	denotes	either
T6900	8007-8009	IN	denotes	on
T6899	7995-8006	NNS	denotes	subclusters
T6898	7991-7994	CD	denotes	two
T6897	7988-7990	IN	denotes	in
T6896	7978-7981	VBP	denotes	are
T6895	7982-7987	VBN	denotes	found
T6894	7971-7977	NNS	denotes	Tas2rs
T6893	7967-7970	DT	denotes	The
T6892	7966-8137	sentence	denotes	The Tas2rs are found in two subclusters on either side of the polymorphic marker D6Mit13 (red) and two genes encoding proline-rich salivary proteins (Prp2 and Prh1; red).
T6891	7965-7966	.	denotes	.
T6890	7964-7965	-RRB-	denotes	)
T6889	7959-7964	JJ	denotes	black
T6888	7958-7959	-LRB-	denotes	(
T6887	7956-7957	CD	denotes	6
T6886	7945-7955	NN	denotes	chromosome
T6885	7938-7944	JJ	denotes	distal
T6884	7935-7937	IN	denotes	to
T6883	7931-7934	VBP	denotes	map
T6882	7919-7924	NN	denotes	Tas2r
T6881	7912-7918	JJ	denotes	intact
T6880	7925-7930	NNS	denotes	genes
T6879	7906-7907	HYPH	denotes	-
T6878	7907-7911	CD	denotes	four
T6877	7900-7906	CD	denotes	Twenty
T6876	7899-7966	sentence	denotes	Twenty-four intact Tas2r genes map to distal chromosome 6 (black).
T6875	7898-7899	.	denotes	.
T6874	7885-7890	NN	denotes	Tas2r
T6873	7883-7884	CD	denotes	6
T6872	7872-7882	NN	denotes	chromosome
T6871	7865-7871	JJ	denotes	distal
T6870	7891-7898	NN	denotes	cluster
T6869	7861-7864	DT	denotes	the
T6868	7858-7860	IN	denotes	of
T6867	7854-7857	NN	denotes	map
T6866	7852-7853	DT	denotes	A
T6836	7840-7841	.	denotes	.
T6835	7831-7840	JJ	denotes	tentative
T6834	7826-7827	-RRB-	denotes	)
T6833	7825-7826	SYM	denotes	*
T6832	7824-7825	-LRB-	denotes	(
T6831	7815-7823	NN	denotes	D6Mit194
T6830	7812-7814	IN	denotes	of
T6829	7828-7830	VBZ	denotes	is
T6828	7794-7802	JJ	denotes	physical
T6827	7803-7811	NN	denotes	position
T6826	7790-7793	DT	denotes	The
T6825	7789-7841	sentence	denotes	The physical position of D6Mit194 (*) is tentative.
T6824	7788-7789	.	denotes	.
T6823	7776-7781	NN	denotes	mouse
T6822	7773-7775	NN	denotes	B6
T6821	7782-7788	NN	denotes	genome
T6820	7769-7772	DT	denotes	the
T7269	13099-13102	VBP	denotes	are
T7268	13094-13098	IN	denotes	than
T7267	13086-13088	NN	denotes	mM
T7266	13084-13085	CD	denotes	3
T7265	13080-13083	CC	denotes	and
T7264	13089-13093	NN	denotes	QHCl
T7263	13077-13079	NN	denotes	mM
T6819	7766-7768	IN	denotes	of
T6818	7755-7759	CD	denotes	2004
T6817	7753-7755	,	denotes	,
T6816	7750-7753	NNP	denotes	May
T6815	7760-7765	NN	denotes	build
T6814	7746-7749	DT	denotes	the
T6813	7743-7745	IN	denotes	on
T6812	7737-7742	VBN	denotes	based
T6811	7733-7736	VBP	denotes	are
T6810	7729-7732	CC	denotes	and
T6809	7727-7729	,	denotes	,
T6808	7725-7727	NN	denotes	Mb
T6807	7722-7724	IN	denotes	in
T6806	7712-7715	VBP	denotes	are
T6805	7692-7703	JJ	denotes	polymorphic
T6804	7704-7711	NNS	denotes	markers
T6803	7688-7691	DT	denotes	the
T6802	7685-7687	IN	denotes	of
T6801	7716-7721	VBN	denotes	given
T6800	7675-7684	NNS	denotes	positions
T6799	7666-7674	JJ	denotes	Physical
T6798	7665-7789	sentence	denotes	Physical positions of the polymorphic markers are given in Mb, and are based on the May, 2004 build of the B6 mouse genome.
T6797	7664-7665	.	denotes	.
T6796	7663-7664	-RRB-	denotes	)
T6795	7655-7659	JJ	denotes	gray
T6794	7660-7663	NN	denotes	box
T6793	7654-7655	-LRB-	denotes	(
T6792	7647-7653	NNS	denotes	Tas2rs
T6791	7643-7646	DT	denotes	the
T6790	7641-7643	,	denotes	,
T6789	7627-7635	NN	denotes	receptor
T6788	7621-7626	NN	denotes	taste
T6787	7614-7620	JJ	denotes	bitter
T6786	7636-7641	NNS	denotes	genes
T6785	7605-7613	JJ	denotes	putative
T6784	7602-7604	IN	denotes	of
T6783	7594-7601	NN	denotes	cluster
T6782	7592-7593	DT	denotes	a
T6781	7581-7582	-RRB-	denotes	)
T6780	7578-7581	CD	denotes	374
T6779	7572-7577	NN	denotes	D6Mit
T6778	7568-7571	CC	denotes	and
T6777	7560-7567	NN	denotes	D6Mit61
T6776	7552-7559	NNS	denotes	markers
T6775	7543-7551	JJ	denotes	unlinked
T6774	7535-7542	IN	denotes	between
T6773	7530-7534	VBZ	denotes	lies
T6772	7524-7529	WDT	denotes	which
T6771	7523-7524	-LRB-	denotes	(
T6770	7514-7518	NN	denotes	QHCl
T6769	7519-7522	NN	denotes	QTL
T6768	7510-7513	DT	denotes	The
T6767	7508-7509	-RRB-	denotes	)
T6766	7583-7591	VBZ	denotes	contains
T6765	7507-7508	LS	denotes	B
T6764	7506-7507	-LRB-	denotes	(
T6763	7505-7665	sentence	denotes	(B) The QHCl QTL (which lies between unlinked markers D6Mit61 and D6Mit 374) contains a cluster of putative bitter taste receptor genes, the Tas2rs (gray box).
T6762	7504-7505	.	denotes	.
T6761	7492-7504	NN	denotes	significance
T6760	7486-7487	HYPH	denotes	-
T6759	7487-7491	JJ	denotes	wide
T6758	7480-7486	NN	denotes	genome
T6757	7470-7479	VBZ	denotes	indicates
T6756	7458-7464	JJ	denotes	dashed
T6755	7465-7469	NN	denotes	line
T6754	7454-7457	DT	denotes	The
T6753	7453-7505	sentence	denotes	The dashed line indicates genome-wide significance.
T6752	7452-7453	.	denotes	.
T6751	7451-7452	-RRB-	denotes	)
T6750	7447-7451	NN	denotes	bold
T6749	7446-7447	-LRB-	denotes	(
T6748	7438-7445	NN	denotes	D6Mit13
T6747	7419-7430	JJ	denotes	polymorphic
T6746	7431-7437	NN	denotes	marker
T6745	7415-7418	DT	denotes	the
T6744	7410-7414	IN	denotes	with
T6743	7399-7401	JJ	denotes	RI
T6742	7402-7409	NNS	denotes	strains
T6741	7395-7398	NN	denotes	BXD
T6740	7388-7394	IN	denotes	across
T6722	7303-7306	NN	denotes	map
T6721	7290-7293	DT	denotes	the
T6720	7287-7289	IN	denotes	in
T6719	7281-7286	VBN	denotes	shown
T6718	7278-7280	IN	denotes	As
T6717	7276-7277	-RRB-	denotes	)
T6716	7368-7378	VBZ	denotes	correlates
T6715	7275-7276	LS	denotes	A
T6714	7274-7275	-LRB-	denotes	(
T6713	7273-7453	sentence	denotes	(A) As shown in the interval map for chromosome 6, the trait value (lick ratio for 1 mM QHCl) correlates strongly across BXD RI strains with the polymorphic marker D6Mit13 (bold).
T6712	7272-7273	.	denotes	.
T6711	7271-7272	CD	denotes	6
T6710	7260-7270	NN	denotes	chromosome
T6709	7257-7259	IN	denotes	on
T6708	7243-7249	JJ	denotes	single
T6707	7250-7256	NN	denotes	marker
T6706	7241-7242	DT	denotes	a
T6705	7238-7240	IN	denotes	to
T6704	7228-7230	VBZ	denotes	is
T6703	7231-7237	VBN	denotes	linked
T6702	7219-7223	NN	denotes	QHCl
T6701	7224-7227	NN	denotes	QTL
T6700	7215-7218	DT	denotes	The
T6675	5328-5329	.	denotes	.
T6674	5316-5328	NN	denotes	significance
T6673	5310-5311	HYPH	denotes	-
T6672	5311-5315	JJ	denotes	wide
T6671	5304-5310	NN	denotes	genome
T6670	5294-5303	VBZ	denotes	indicates
T6669	5282-5288	JJ	denotes	dashed
T6668	5289-5293	NN	denotes	line
T6667	5278-5281	DT	denotes	The
T6666	5277-5329	sentence	denotes	The dashed line indicates genome-wide significance.
T6665	5276-5277	.	denotes	.
T6664	5275-5276	-RRB-	denotes	)
T6663	5269-5275	JJ	denotes	yellow
T6662	5268-5269	-LRB-	denotes	(
T6661	5257-5267	JJ	denotes	suggestive
T6660	5248-5251	NN	denotes	QTL
T6659	5243-5247	DT	denotes	both
T6658	5241-5243	,	denotes	,
T6657	5237-5241	NN	denotes	QHCl
T6656	5234-5236	NN	denotes	mM
T6655	5232-5233	CD	denotes	3
T6654	5228-5231	IN	denotes	For
T6653	5226-5227	-RRB-	denotes	)
T6652	5252-5256	VBD	denotes	were
T6651	5214-5220	JJ	denotes	Bottom
T6650	5221-5226	NN	denotes	panel
T6649	5213-5214	-LRB-	denotes	(
T6648	5212-5277	sentence	denotes	(Bottom panel) For 3 mM QHCl, both QTL were suggestive (yellow).
T6647	5211-5212	.	denotes	.
T6646	5207-5211	NN	denotes	QHCl
T6645	5204-5206	NN	denotes	mM
T6644	5202-5203	CD	denotes	1
T6643	5199-5201	IN	denotes	to
T6642	5189-5198	NNS	denotes	responses
T6641	5183-5188	NN	denotes	taste
T6640	5173-5182	VBG	denotes	affecting
T6639	5171-5172	-RRB-	denotes	)
T6638	5165-5171	JJ	denotes	yellow
T6637	5164-5165	-LRB-	denotes	(
T6636	5162-5163	CD	denotes	8
T6635	5151-5161	NN	denotes	chromosome
T6634	5148-5150	IN	denotes	on
T6633	5133-5143	JJ	denotes	suggestive
T6632	5144-5147	NN	denotes	QTL
T6631	5131-5132	DT	denotes	a
T6630	5127-5130	CC	denotes	and
T6629	5125-5126	-RRB-	denotes	)
T6628	5120-5125	JJ	denotes	green
T6627	5119-5120	-LRB-	denotes	(
T6626	5117-5118	CD	denotes	6
T6625	5106-5116	NN	denotes	chromosome
T6624	5103-5105	IN	denotes	on
T6623	5087-5098	JJ	denotes	significant
T6622	5099-5102	NN	denotes	QTL
T6621	5085-5086	DT	denotes	a
T6620	5077-5078	-RRB-	denotes	)
T6619	5070-5077	NNS	denotes	Methods
T6618	5066-5069	VB	denotes	see
T6617	5065-5066	-LRB-	denotes	(
T6616	5052-5060	NN	denotes	interval
T6615	5061-5064	NN	denotes	map
T6614	5048-5051	DT	denotes	The
T6613	5046-5047	-RRB-	denotes	)
T6612	5079-5084	VBZ	denotes	shows
T6611	5037-5040	JJ	denotes	Top
T6610	5041-5046	NN	denotes	panel
T6609	5036-5037	-LRB-	denotes	(
T6608	5035-5212	sentence	denotes	(Top panel) The interval map (see Methods) shows a significant QTL on chromosome 6 (green) and a suggestive QTL on chromosome 8 (yellow) affecting taste responses to 1 mM QHCl.
T6607	5034-5035	.	denotes	.
T6606	5033-5034	CD	denotes	6
T6605	5022-5032	NN	denotes	chromosome
T6604	5016-5021	NN	denotes	mouse
T6603	5013-5015	IN	denotes	on
T6602	5007-5012	NN	denotes	taste
T6601	5002-5006	NN	denotes	QHCl
T6600	4998-5001	IN	denotes	for
T6599	4988-4993	JJ	denotes	major
T6598	4994-4997	NN	denotes	QTL
T6597	4986-4987	DT	denotes	A
T7046	10910-10911	-LRB-	denotes	(
T7045	10900-10909	NN	denotes	phenotype
T7044	10893-10899	NN	denotes	taster
T7043	10888-10892	NN	denotes	QHCl
T7042	10883-10887	IN	denotes	with
T7041	10865-10871	RB	denotes	always
T7040	10861-10864	VBD	denotes	was
T7039	10852-10860	NN	denotes	genotype
T7038	10846-10851	NN	denotes	Tas2r
T7037	10844-10846	,	denotes	,
T7036	10838-10844	VBN	denotes	tested
T7035	10826-10829	NN	denotes	BXD
T7034	10823-10825	CD	denotes	17
T7033	10830-10837	NNS	denotes	strains
T7032	10819-10822	DT	denotes	the
T7031	10816-10818	IN	denotes	of
T7030	10811-10815	DT	denotes	each
T7029	10872-10882	VBN	denotes	correlated
T7028	10808-10810	IN	denotes	In
T7027	10807-10966	sentence	denotes	In each of the 17 BXD strains tested, Tas2r genotype was always correlated with QHCl taster phenotype (blue = B6 taster phenotype, red = D2 taster phenotype).
T7026	10806-10807	.	denotes	.
T7025	10805-10806	-RRB-	denotes	)
T7024	10797-10805	NN	denotes	Tas2r120
T7023	10796-10797	-LRB-	denotes	(
T7022	10784-10787	NN	denotes	PCR
T7021	10788-10795	NN	denotes	product
T7020	10782-10783	DT	denotes	a
T7019	10779-10781	IN	denotes	of
T7018	10771-10778	NN	denotes	absence
T7017	10768-10770	CC	denotes	or
T7016	10759-10767	NN	denotes	presence
T7015	10755-10758	DT	denotes	the
T7014	10752-10754	IN	denotes	on
T7013	10749-10751	CC	denotes	or
T7012	10747-10748	-RRB-	denotes	)
T7011	10739-10747	NN	denotes	Tas2r131
T7010	10735-10738	CC	denotes	and
T7009	10726-10734	NN	denotes	Tas2r116
T7008	10724-10726	,	denotes	,
T7007	10716-10724	NN	denotes	Tas2r105
T7006	10715-10716	-LRB-	denotes	(
T7005	10702-10705	NN	denotes	PCR
T7004	10706-10714	NNS	denotes	products
T7003	10692-10701	VBN	denotes	amplified
T7002	10689-10691	IN	denotes	of
T7001	10669-10680	NN	denotes	restriction
T7000	10681-10688	NNS	denotes	digests
T6999	10658-10668	JJ	denotes	diagnostic
T6998	10655-10657	IN	denotes	on
T6997	10649-10654	VBN	denotes	based
T6996	10631-10633	VB	denotes	be
T6995	10627-10630	MD	denotes	can
T6994	10620-10626	NNS	denotes	Tas2rs
T6993	10615-10619	CD	denotes	four
T6992	10612-10614	IN	denotes	of
T6991	10634-10648	VBN	denotes	differentiated
T6990	10601-10603	NN	denotes	D2
T6989	10597-10600	CC	denotes	and
T6988	10604-10611	NNS	denotes	alleles
T6987	10594-10596	NN	denotes	B6
T6986	10593-10807	sentence	denotes	B6 and D2 alleles of four Tas2rs can be differentiated based on diagnostic restriction digests of amplified PCR products (Tas2r105, Tas2r116 and Tas2r131) or on the presence or absence of a PCR product (Tas2r120).
T6985	10592-10593	.	denotes	.
T6984	10586-10592	NNS	denotes	Tas2rs
T6983	10581-10585	CD	denotes	four
T6982	10577-10580	IN	denotes	for
T6981	10569-10576	NNS	denotes	strains
T6980	10562-10568	IN	denotes	across
T6979	10552-10561	NN	denotes	variation
T6978	10544-10551	JJ	denotes	Allelic
T6576	4005-4006	.	denotes	.
T6575	3998-4005	NN	denotes	control
T6574	3988-3997	JJ	denotes	polygenic
T6573	3982-3987	IN	denotes	under
T6572	3974-3978	NN	denotes	QHCL
T6571	3971-3973	IN	denotes	to
T6570	3959-3970	NN	denotes	sensitivity
T6569	3979-3981	VBZ	denotes	is
T6568	3954-3958	IN	denotes	that
T6567	3926-3936	JJ	denotes	phenotypic
T6566	3917-3925	JJ	denotes	distinct
T6565	3937-3944	NNS	denotes	classes
T6564	3913-3916	CD	denotes	two
T6563	3910-3912	IN	denotes	of
T6562	3945-3953	VBZ	denotes	suggests
T6561	3902-3909	NN	denotes	absence
T6560	3898-3901	DT	denotes	The
T6559	3897-4006	sentence	denotes	The absence of two distinct phenotypic classes suggests that sensitivity to QHCL is under polygenic control.
T6558	3896-3897	.	denotes	.
T6557	3891-3892	SYM	denotes	>
T6556	3893-3896	CD	denotes	0.6
T6555	3883-3890	NNS	denotes	strains
T6554	3871-3882	JJ	denotes	insensitive
T6553	3867-3870	CC	denotes	and
T6552	3865-3867	,	denotes	,
T6551	3861-3862	SYM	denotes	-
T6550	3857-3861	CD	denotes	0.31
T6549	3852-3856	IN	denotes	from
T6548	3862-3865	CD	denotes	0.6
T6547	3844-3851	NNS	denotes	strains
T6546	3831-3843	JJ	denotes	intermediate
T6545	3829-3831	,	denotes	,
T6544	3826-3829	CD	denotes	0.3
T6543	3824-3825	SYM	denotes	≤
T6542	3821-3823	IN	denotes	of
T6541	3816-3820	NN	denotes	QHCl
T6540	3813-3815	NN	denotes	mM
T6539	3811-3812	CD	denotes	1
T6538	3807-3810	IN	denotes	for
T6537	3796-3800	NN	denotes	lick
T6536	3801-3806	NN	denotes	ratio
T6535	3794-3795	DT	denotes	a
T6534	3776-3783	NNS	denotes	strains
T6533	3766-3775	JJ	denotes	sensitive
T6532	3764-3766	:	denotes	:
T6531	3760-3764	NN	denotes	QHCl
T6530	3757-3759	NN	denotes	mM
T6529	3755-3756	CD	denotes	1
T6528	3752-3754	IN	denotes	at
T6527	3742-3751	NN	denotes	phenotype
T6526	3738-3741	DT	denotes	the
T6525	3735-3737	IN	denotes	of
T6524	3724-3734	NN	denotes	continuity
T6523	3722-3723	DT	denotes	a
T6522	3712-3717	EX	denotes	there
T6521	3718-3721	VBD	denotes	was
T6520	3709-3711	IN	denotes	as
T6519	3707-3709	,	denotes	,
T6518	3784-3793	VBD	denotes	exhibited
T6517	3692-3703	RB	denotes	arbitrarily
T6516	3687-3691	VBD	denotes	were
T6515	3673-3679	NN	denotes	taster
T6514	3668-3672	NN	denotes	QHCl
T6513	3662-3667	CD	denotes	three
T6512	3680-3686	NNS	denotes	groups
T6511	3658-3661	DT	denotes	the
T6510	3654-3657	IN	denotes	for
T6509	3704-3707	VBN	denotes	set
T6508	3646-3653	NNS	denotes	Cutoffs
T6507	3645-3897	sentence	denotes	Cutoffs for the three QHCl taster groups were arbitrarily set, as there was a continuity of the phenotype at 1 mM QHCl: sensitive strains exhibited a lick ratio for 1 mM QHCl of ≤ 0.3, intermediate strains from 0.31-0.6, and insensitive strains > 0.6.
T6403	3205-3211	NNS	denotes	panels
T6402	3244-3255	VBN	denotes	represented
T6401	3201-3204	IN	denotes	For
T6400	3200-3350	sentence	denotes	For panels B, C, and D, each BXD strain is represented by a different color, and listed in order from least sensitive to most sensitive to 1 mM QHCL.
T6399	3199-3200	.	denotes	.
T6398	3191-3199	NN	denotes	stimulus
T6397	3187-3190	DT	denotes	the
T6396	3184-3186	IN	denotes	to
T6395	3182-3184	,	denotes	,
T6394	3165-3170	NN	denotes	taste
T6393	3157-3164	JJR	denotes	greater
T6392	3171-3182	NN	denotes	sensitivity
T6391	3147-3156	RB	denotes	therefore
T6390	3143-3146	CC	denotes	and
T6389	3141-3143	,	denotes	,
T6388	3125-3132	JJR	denotes	greater
T6387	3133-3141	NN	denotes	aversion
T6386	3123-3124	DT	denotes	a
T6385	3102-3106	NN	denotes	lick
T6384	3097-3101	NN	denotes	mean
T6383	3091-3096	JJR	denotes	lower
T6382	3107-3112	NN	denotes	ratio
T6381	3089-3090	DT	denotes	a
T6380	3087-3089	,	denotes	,
T6379	3081-3087	NNS	denotes	panels
T6378	3077-3080	DT	denotes	all
T6377	3113-3122	VBZ	denotes	indicates
T6376	3074-3076	IN	denotes	In
T6375	3073-3200	sentence	denotes	In all panels, a lower mean lick ratio indicates a greater aversion, and therefore greater taste sensitivity, to the stimulus.
T6374	3072-3073	.	denotes	.
T6373	3070-3072	NN	denotes	DB
T6372	3066-3069	CC	denotes	and
T6371	3061-3065	NN	denotes	QHCl
T6370	3058-3060	IN	denotes	of
T6369	3043-3057	NNS	denotes	concentrations
T6368	3039-3042	CD	denotes	two
T6367	3036-3038	IN	denotes	at
T6366	3029-3030	-RRB-	denotes	)
T6365	3017-3021	JJ	denotes	open
T6364	3022-3029	NNS	denotes	circles
T6363	3016-3017	-LRB-	denotes	(
T6362	3013-3015	NN	denotes	D2
T6361	3009-3012	CC	denotes	and
T6360	3007-3008	-RRB-	denotes	)
T6359	2993-2999	VBN	denotes	filled
T6358	3000-3007	NNS	denotes	circles
T6357	2992-2993	-LRB-	denotes	(
T6356	3031-3035	NNS	denotes	mice
T6355	2989-2991	NN	denotes	B6
T6354	2985-2988	IN	denotes	for
T6353	2973-2977	NN	denotes	lick
T6352	2968-2972	NN	denotes	Mean
T6351	2966-2967	-RRB-	denotes	)
T6350	2978-2984	NNS	denotes	ratios
T6349	2965-2966	LS	denotes	A
T6348	2964-2965	-LRB-	denotes	(
T6347	2963-3073	sentence	denotes	(A) Mean lick ratios for B6 (filled circles) and D2 (open circles) mice at two concentrations of QHCl and DB.
T6346	2962-2963	.	denotes	.
T6345	2951-2954	NN	denotes	BXD
T6344	2947-2950	CC	denotes	and
T6343	2944-2946	NN	denotes	D2
T6342	2942-2944	,	denotes	,
T6341	2955-2962	NNS	denotes	strains
T6340	2940-2942	NN	denotes	B6
T6339	2936-2939	IN	denotes	for
T6338	2934-2935	-RRB-	denotes	)
T6337	2930-2931	SYM	denotes	±
T6336	2925-2929	NN	denotes	mean
T6335	2932-2934	NN	denotes	SE
T6334	2924-2925	-LRB-	denotes	(
T6333	2917-2923	NNS	denotes	ratios
T6332	2912-2916	NN	denotes	Lick
T6739	7379-7387	RB	denotes	strongly
T6738	7366-7367	-RRB-	denotes	)
T6737	7362-7366	NN	denotes	QHCl
T6736	7359-7361	NN	denotes	mM
T6735	7357-7358	CD	denotes	1
T6734	7353-7356	IN	denotes	for
T6733	7347-7352	NN	denotes	ratio
T6732	7342-7346	NN	denotes	lick
T6731	7341-7342	-LRB-	denotes	(
T6730	7329-7334	NN	denotes	trait
T6729	7335-7340	NN	denotes	value
T6728	7325-7328	DT	denotes	the
T6727	7323-7325	,	denotes	,
T6726	7322-7323	CD	denotes	6
T6725	7311-7321	NN	denotes	chromosome
T6724	7307-7310	IN	denotes	for
T6723	7294-7302	JJ	denotes	interval
T6506	3644-3645	.	denotes	.
T6505	3643-3644	-RRB-	denotes	)
T6504	3642-3643	NN	denotes	C
T6503	3641-3642	-LRB-	denotes	(
T6502	3637-3640	CC	denotes	and
T6501	3635-3636	-RRB-	denotes	)
T6500	3634-3635	NN	denotes	B
T6499	3633-3634	-LRB-	denotes	(
T6498	3630-3632	IN	denotes	in
T6497	3624-3629	DT	denotes	those
T6496	3621-3623	IN	denotes	to
T6495	3603-3608	NN	denotes	taste
T6494	3609-3620	NN	denotes	sensitivity
T6493	3598-3602	NN	denotes	QHCl
T6492	3595-3597	IN	denotes	in
T6491	3582-3594	JJ	denotes	intermediate
T6490	3570-3573	NN	denotes	BXD
T6489	3566-3569	CD	denotes	six
T6488	3574-3581	NNS	denotes	strains
T6487	3562-3565	DT	denotes	the
T6486	3558-3561	IN	denotes	for
T6485	3546-3550	NN	denotes	lick
T6484	3541-3545	NN	denotes	Mean
T6483	3539-3540	-RRB-	denotes	)
T6482	3551-3557	NNS	denotes	ratios
T6481	3538-3539	LS	denotes	D
T6480	3537-3538	-LRB-	denotes	(
T6479	3536-3645	sentence	denotes	(D) Mean lick ratios for the six BXD strains intermediate in QHCl taste sensitivity to those in (B) and (C).
T6478	3535-3536	.	denotes	.
T6477	3530-3535	NN	denotes	assay
T6476	3525-3529	DT	denotes	this
T6475	3522-3524	IN	denotes	in
T6474	3517-3521	NN	denotes	QHCl
T6473	3514-3516	IN	denotes	to
T6472	3504-3513	JJ	denotes	sensitive
T6471	3498-3503	RBS	denotes	least
T6470	3494-3497	VBP	denotes	are
T6469	3489-3493	WDT	denotes	that
T6468	3477-3480	NN	denotes	BXD
T6467	3472-3476	CD	denotes	five
T6466	3481-3488	NNS	denotes	strains
T6465	3468-3471	DT	denotes	the
T6464	3464-3467	IN	denotes	for
T6463	3452-3456	NN	denotes	lick
T6462	3447-3451	NN	denotes	Mean
T6461	3445-3446	-RRB-	denotes	)
T6460	3457-3463	NNS	denotes	ratios
T6459	3444-3445	LS	denotes	C
T6458	3443-3444	-LRB-	denotes	(
T6457	3442-3536	sentence	denotes	(C) Mean lick ratios for the five BXD strains that are least sensitive to QHCl in this assay.
T6456	3441-3442	.	denotes	.
T6455	3436-3441	NN	denotes	assay
T6454	3431-3435	DT	denotes	this
T6453	3428-3430	IN	denotes	in
T6452	3423-3427	NN	denotes	QHCl
T6451	3420-3422	IN	denotes	to
T6450	3410-3419	JJ	denotes	sensitive
T6449	3405-3409	RBS	denotes	most
T6448	3401-3404	VBP	denotes	are
T6447	3396-3400	WDT	denotes	that
T6446	3384-3387	NN	denotes	BXD
T6445	3380-3383	CD	denotes	six
T6444	3388-3395	NNS	denotes	strains
T6443	3376-3379	DT	denotes	the
T6442	3372-3375	IN	denotes	for
T6441	3360-3364	NN	denotes	lick
T6440	3355-3359	NN	denotes	Mean
T6439	3353-3354	-RRB-	denotes	)
T6438	3365-3371	NNS	denotes	ratios
T6437	3352-3353	LS	denotes	B
T6436	3351-3352	-LRB-	denotes	(
T6435	3350-3442	sentence	denotes	(B) Mean lick ratios for the six BXD strains that are most sensitive to QHCl in this assay.
T6434	3349-3350	.	denotes	.
T6433	3345-3349	NN	denotes	QHCL
T6432	3342-3344	NN	denotes	mM
T6431	3340-3341	CD	denotes	1
T6430	3337-3339	IN	denotes	to
T6429	3327-3336	JJ	denotes	sensitive
T6428	3322-3326	RBS	denotes	most
T6427	3319-3321	IN	denotes	to
T6426	3309-3318	JJ	denotes	sensitive
T6425	3303-3308	JJS	denotes	least
T6424	3298-3302	IN	denotes	from
T6423	3292-3297	NN	denotes	order
T6422	3289-3291	IN	denotes	in
T6421	3282-3288	VBN	denotes	listed
T6420	3278-3281	CC	denotes	and
T6419	3276-3278	,	denotes	,
T6418	3261-3270	JJ	denotes	different
T6417	3271-3276	NN	denotes	color
T6416	3259-3260	DT	denotes	a
T6415	3256-3258	IN	denotes	by
T6414	3241-3243	VBZ	denotes	is
T6413	3230-3233	NN	denotes	BXD
T6412	3234-3240	NN	denotes	strain
T6411	3225-3229	DT	denotes	each
T6410	3223-3225	,	denotes	,
T6409	3222-3223	NN	denotes	D
T6408	3218-3221	CC	denotes	and
T6407	3216-3218	,	denotes	,
T6406	3215-3216	NN	denotes	C
T6405	3213-3215	,	denotes	,
T6404	3212-3213	NN	denotes	B
T3406	12411-12412	.	denotes	.
T3405	12405-12411	NN	denotes	status
T3404	12398-12404	NN	denotes	taster
T3403	12393-12397	NN	denotes	QHCl
T3402	12388-12392	IN	denotes	with
T3401	12381-12387	VBZ	denotes	varies
T3400	12376-12380	WDT	denotes	that
T3399	12359-12365	JJ	denotes	single
T3398	12366-12375	NN	denotes	haplotype
T3397	12357-12358	DT	denotes	a
T3396	12340-12345	NN	denotes	Tas2r
T3395	12333-12339	JJ	denotes	entire
T3394	12346-12353	NN	denotes	cluster
T3393	12329-12332	DT	denotes	the
T3392	12354-12356	VBZ	denotes	is
T3391	12324-12328	IN	denotes	that
T3390	12313-12323	VBG	denotes	suggesting
T3389	12311-12313	,	denotes	,
T3388	12310-12311	-RRB-	denotes	)
T3387	12307-12309	,	denotes	,
T3386	12306-12307	CD	denotes	6
T3385	12298-12305	NNS	denotes	Figures
T3384	12309-12310	CD	denotes	7
T3383	12297-12298	-LRB-	denotes	(
T3382	12281-12286	NN	denotes	taste
T3381	12276-12280	NN	denotes	QHCl
T3380	12287-12296	NN	denotes	phenotype
T3379	12272-12275	DT	denotes	the
T3378	12267-12271	IN	denotes	with
T3377	12249-12255	RB	denotes	always
T3376	12238-12243	NN	denotes	Tas2r
T3375	12244-12248	NN	denotes	gene
T3374	12233-12237	DT	denotes	each
T3373	12230-12232	IN	denotes	of
T3372	12221-12229	NN	denotes	genotype
T3371	12217-12220	DT	denotes	the
T3370	12215-12217	,	denotes	,
T3369	12256-12266	VBD	denotes	correlated
T3368	12204-12215	RB	denotes	Furthermore
T3367	12203-12412	sentence	denotes	Furthermore, the genotype of each Tas2r gene always correlated with the QHCl taste phenotype (Figures 6, 7), suggesting that the entire Tas2r cluster is a single haplotype that varies with QHCl taster status.
T3366	12202-12203	.	denotes	.
T3365	12201-12202	-RRB-	denotes	)
T3364	12198-12200	,	denotes	,
T3363	12197-12198	CD	denotes	5
T3362	12189-12196	NNS	denotes	Figures
T3361	12200-12201	CD	denotes	6
T3360	12188-12189	-LRB-	denotes	(
T3359	12172-12180	JJ	denotes	parental
T3358	12167-12171	JJ	denotes	same
T3357	12181-12187	NN	denotes	strain
T3356	12163-12166	DT	denotes	the
T3355	12158-12162	IN	denotes	from
T3354	12139-12141	JJ	denotes	RI
T3353	12128-12138	JJ	denotes	individual
T3352	12142-12146	NN	denotes	line
T3351	12125-12127	DT	denotes	an
T3350	12118-12124	IN	denotes	within
T3349	12112-12117	NN	denotes	Tas2r
T3348	12106-12111	DT	denotes	every
T3347	12104-12106	,	denotes	,
T3346	12098-12104	VBN	denotes	tested
T3345	12089-12091	JJ	denotes	RI
T3344	12092-12097	NNS	denotes	lines
T3343	12085-12088	DT	denotes	all
T3342	12147-12157	VBD	denotes	originated
T3341	12081-12084	IN	denotes	For
T3340	12080-12203	sentence	denotes	For all RI lines tested, every Tas2r within an individual RI line originated from the same parental strain (Figures 5, 6).
T3339	12079-12080	.	denotes	.
T3338	12071-12073	JJ	denotes	RI
T3337	12067-12070	NN	denotes	BXD
T3336	12074-12079	NNS	denotes	lines
T3335	12063-12066	DT	denotes	the
T3334	12060-12062	IN	denotes	of
T3333	12049-12059	NN	denotes	generation
T3332	12045-12048	DT	denotes	the
T3331	12038-12044	IN	denotes	during
T3330	12028-12029	CD	denotes	6
T3329	12017-12027	NN	denotes	chromosome
T3328	12010-12016	JJ	denotes	distal
T3327	12030-12037	NN	denotes	cluster
T3326	12006-12009	DT	denotes	the
T3325	11999-12005	IN	denotes	within
T3324	11978-11991	NN	denotes	recombination
T3323	11969-11977	JJ	denotes	apparent
T3322	11992-11998	NNS	denotes	events
T3321	11966-11968	DT	denotes	no
T3320	11956-11960	VBP	denotes	have
T3319	11950-11955	EX	denotes	there
T3318	11961-11965	VBN	denotes	been
T3317	11945-11949	IN	denotes	that
T3316	11931-11933	PRP	denotes	we
T3315	11929-11931	,	denotes	,
T3314	11934-11944	VBD	denotes	discovered
T3313	11917-11929	RB	denotes	Surprisingly
T3312	11916-12080	sentence	denotes	Surprisingly, we discovered that there have been no apparent recombination events within the distal chromosome 6 cluster during the generation of the BXD RI lines.
T3311	11915-11916	.	denotes	.
T3310	11911-11915	NN	denotes	gene
T3309	11906-11910	DT	denotes	this
T3308	11902-11905	IN	denotes	for
T3307	11890-11892	NN	denotes	D2
T3306	11893-11901	NN	denotes	genotype
T3305	11886-11889	DT	denotes	the
T3304	11883-11885	IN	denotes	of
T3303	11872-11882	JJ	denotes	diagnostic
T3302	11856-11859	NN	denotes	PCR
T3301	11860-11867	NN	denotes	product
T3300	11854-11855	DT	denotes	a
T3299	11851-11853	IN	denotes	of
T3298	11843-11850	NN	denotes	absence
T3297	11839-11842	DT	denotes	the
T3296	11837-11839	,	denotes	,
T3295	11833-11837	NNS	denotes	mice
T3294	11830-11832	NN	denotes	D2
T3293	11827-11829	IN	denotes	in
T3292	11812-11818	RB	denotes	likely
T3291	11809-11811	VBZ	denotes	is
T3290	11819-11826	VBN	denotes	deleted
T3289	11803-11808	WDT	denotes	which
T3288	11801-11803	,	denotes	,
T3287	11793-11801	NN	denotes	Tas2r120
T3286	11868-11871	VBD	denotes	was
T3285	11789-11792	IN	denotes	For
T3284	11788-11916	sentence	denotes	For Tas2r120, which is likely deleted in D2 mice, the absence of a PCR product was diagnostic of the D2 genotype for this gene.
T3283	11787-11788	.	denotes	.
T3282	11774-11776	VB	denotes	be
T3281	11768-11773	MD	denotes	could
T3280	11743-11754	NN	denotes	restriction
T3260	11656-11657	.	denotes	.
T3259	11647-11649	NN	denotes	D2
T3258	11644-11646	CC	denotes	or
T3257	11641-11643	NN	denotes	B6
T3256	11650-11656	NN	denotes	allele
T3255	11639-11640	DT	denotes	a
T3254	11634-11638	IN	denotes	from
T3253	11620-11623	VBD	denotes	was
T3252	11608-11611	NN	denotes	PCR
T3251	11602-11607	NN	denotes	Tas2r
T3250	11591-11601	JJ	denotes	particular
T3249	11612-11619	NN	denotes	product
T3248	11589-11590	DT	denotes	a
T3247	11624-11633	VBN	denotes	amplified
T3246	11581-11588	IN	denotes	whether
T3245	11564-11571	RB	denotes	quickly
T3244	11561-11563	TO	denotes	to
T3243	11572-11580	VB	denotes	identify
T3242	11558-11560	PRP	denotes	us
T3241	11546-11551	MD	denotes	would
T3240	11552-11557	VB	denotes	allow
T3239	11541-11545	WDT	denotes	that
T3238	11520-11532	NN	denotes	endonuclease
T3237	11508-11519	NN	denotes	restriction
T3236	11533-11540	NNS	denotes	digests
T3235	11497-11507	JJ	denotes	diagnostic
T3234	11488-11496	VB	denotes	identify
T3233	11485-11487	TO	denotes	to
T3232	11480-11484	JJ	denotes	able
T3231	11472-11474	PRP	denotes	we
T3230	11470-11472	,	denotes	,
T3229	11465-11470	NNS	denotes	cases
T3228	11460-11464	JJS	denotes	most
T3227	11475-11479	VBD	denotes	were
T3226	11457-11459	IN	denotes	In
T3225	11456-11657	sentence	denotes	In most cases, we were able to identify diagnostic restriction endonuclease digests that would allow us to quickly identify whether a particular Tas2r PCR product was amplified from a B6 or D2 allele.
T3224	11455-11456	.	denotes	.
T3223	11446-11455	VBD	denotes	contained
T3222	11441-11445	PRP	denotes	they
T3221	11433-11440	VBZ	denotes	alleles
T3220	11427-11432	NN	denotes	Tas2r
T3219	11423-11426	DT	denotes	the
T3218	11419-11422	IN	denotes	for
T3217	11417-11419	,	denotes	,
T3216	11410-11417	NN	denotes	testing
T3215	11404-11409	NN	denotes	taste
T3214	11401-11403	IN	denotes	in
T3213	11392-11395	VBD	denotes	had
T3212	11389-11391	PRP	denotes	we
T3211	11396-11400	VBN	denotes	used
T3210	11384-11388	WDT	denotes	that
T3209	11381-11383	CD	denotes	17
T3208	11377-11380	DT	denotes	the
T3207	11367-11376	VBG	denotes	including
T3206	11365-11367	,	denotes	,
T3205	11357-11359	JJ	denotes	RI
T3204	11353-11356	NN	denotes	BXD
T3203	11343-11352	JJ	denotes	available
T3202	11360-11365	NNS	denotes	lines
T3201	11340-11342	CD	denotes	29
T3200	11335-11339	IN	denotes	from
T3199	11331-11334	NN	denotes	DNA
T3198	11323-11330	JJ	denotes	genomic
T3197	11316-11322	VB	denotes	screen
T3196	11313-11315	TO	denotes	to
T3195	11300-11302	PRP	denotes	we
T3194	11298-11300	,	denotes	,
T3193	11303-11312	VBD	denotes	proceeded
T3192	11289-11298	RB	denotes	Therefore
T3191	11288-11456	sentence	denotes	Therefore, we proceeded to screen genomic DNA from 29 available BXD RI lines, including the 17 that we had used in taste testing, for the Tas2r alleles they contained.
T3190	11287-11288	.	denotes	.
T3189	11276-11287	NN	denotes	sensitivity
T3188	11270-11275	NN	denotes	taste
T3187	11265-11269	NN	denotes	QHCl
T3186	11260-11264	IN	denotes	with
T3185	11245-11248	VBP	denotes	are
T3184	11249-11259	VBN	denotes	correlated
T3183	11231-11236	NN	denotes	Tas2r
T3182	11237-11244	NNS	denotes	alleles
T3181	11225-11230	WDT	denotes	which
T3180	11213-11224	VBG	denotes	determining
T3179	11210-11212	IN	denotes	by
T3178	11200-11205	NN	denotes	taste
T3177	11195-11199	NN	denotes	QHCl
T3176	11206-11209	NN	denotes	QTL
T3175	11191-11194	DT	denotes	the
T3174	11188-11190	IN	denotes	of
T3173	11168-11176	JJ	denotes	physical
T3172	11177-11187	NNS	denotes	boundaries
T3171	11164-11167	DT	denotes	the
T3170	11157-11163	VB	denotes	narrow
T3169	11154-11156	TO	denotes	to
T3168	11145-11153	JJ	denotes	possible
T3167	11136-11141	MD	denotes	might
T3166	11133-11135	PRP	denotes	it
T3165	11142-11144	VB	denotes	be
T3164	11128-11132	IN	denotes	that
T3163	11103-11109	JJ	denotes	inbred
T3162	11099-11102	CD	denotes	two
T3161	11110-11117	NNS	denotes	strains
T3160	11093-11098	DT	denotes	these
T3159	11090-11092	IN	denotes	in
T3158	11080-11089	NNS	denotes	receptors
T3157	11068-11079	JJ	denotes	orthologous
T3156	11060-11067	IN	denotes	between
T3155	11118-11127	VBD	denotes	suggested
T3144	10517-10521	NNS	denotes	data
T3143	10526-10531	VBN	denotes	shown
T3142	10516-10517	-LRB-	denotes	(
T3141	10511-10515	NNS	denotes	T2Rs
T3140	10507-10510	DT	denotes	the
T3139	10504-10506	IN	denotes	of
T3138	10484-10497	JJ	denotes	extracellular
T3137	10480-10483	CD	denotes	two
T3136	10474-10479	JJ	denotes	first
T3135	10498-10503	NNS	denotes	loops
T3134	10470-10473	DT	denotes	the
T3133	10463-10469	IN	denotes	within
T3132	10454-10458	VBN	denotes	seen
T3131	10441-10445	NN	denotes	acid
T3130	10435-10440	NN	denotes	amino
T3129	10446-10453	NNS	denotes	changes
T3128	10431-10434	DT	denotes	the
T3127	10428-10430	IN	denotes	of
T3126	10426-10427	NN	denotes	%
T3125	10424-10426	CD	denotes	23
T3124	10422-10424	,	denotes	,
T3123	10413-10422	NNS	denotes	receptors
T3122	10409-10412	DT	denotes	the
T3121	10406-10408	IN	denotes	of
T3120	10398-10405	NNS	denotes	regions
T3119	10394-10397	DT	denotes	all
T3118	10391-10393	IN	denotes	in
T3117	10459-10462	VBP	denotes	are
T3116	10381-10384	VBP	denotes	are
T3115	10371-10373	NN	denotes	D2
T3114	10367-10370	CC	denotes	and
T3113	10374-10380	NNS	denotes	Tas2rs
T3112	10364-10366	NN	denotes	B6
T3111	10356-10363	IN	denotes	between
T3110	10347-10355	NNS	denotes	residues
T3109	10335-10346	JJ	denotes	polymorphic
T3108	10385-10390	VBN	denotes	found
T3107	10326-10334	IN	denotes	Although
T3106	10325-10533	sentence	denotes	Although polymorphic residues between B6 and D2 Tas2rs are found in all regions of the receptors, 23% of the amino acid changes seen are within the first two extracellular loops of the T2Rs (data not shown).
T3105	10324-10325	.	denotes	.
T3104	10323-10324	-RRB-	denotes	)
T3103	10314-10317	RB	denotes	not
T3102	10309-10313	NNS	denotes	data
T3101	10318-10323	VBN	denotes	shown
T3100	10308-10309	-LRB-	denotes	(
T3099	10302-10307	NNS	denotes	exons
T3098	10295-10301	NN	denotes	coding
T3097	10288-10294	IN	denotes	within
T3096	10280-10287	JJ	denotes	present
T3095	10276-10279	VBP	denotes	are
T3094	10251-10261	NN	denotes	nucleotide
T3093	10244-10250	JJ	denotes	single
T3092	10262-10275	NNS	denotes	polymorphisms
T3091	10240-10243	CD	denotes	307
T3090	10236-10239	CC	denotes	and
T3089	10234-10236	,	denotes	,
T3088	10227-10229	NN	denotes	D2
T3087	10223-10226	CC	denotes	and
T3086	10230-10234	NNS	denotes	mice
T3085	10220-10222	NN	denotes	B6
T3084	10217-10219	IN	denotes	in
T3083	10209-10216	NNS	denotes	alleles
T3082	10199-10208	JJ	denotes	different
T3081	10185-10193	VBN	denotes	examined
T3080	10194-10198	VBP	denotes	have
T3079	10175-10177	CD	denotes	24
T3078	10178-10184	NNS	denotes	Tas2rs
T3077	10171-10174	DT	denotes	All
T3076	10170-10325	sentence	denotes	All 24 Tas2rs examined have different alleles in B6 and D2 mice, and 307 single nucleotide polymorphisms are present within coding exons (data not shown).
T3075	10169-10170	.	denotes	.
T3074	10151-10159	NN	denotes	missense
T3073	10148-10150	CD	denotes	16
T3072	10144-10147	CC	denotes	and
T3071	10160-10169	NNS	denotes	mutations
T3070	10140-10143	CD	denotes	one
T3069	10132-10139	IN	denotes	between
T3068	10122-10131	VBD	denotes	contained
T3067	10112-10114	CD	denotes	19
T3066	10102-10111	VBG	denotes	remaining
T3065	10115-10121	NNS	denotes	Tas2rs
T3064	10098-10101	DT	denotes	The
T3063	10097-10170	sentence	denotes	The remaining 19 Tas2rs contained between one and 16 missense mutations.
T3062	10096-10097	.	denotes	.
T3061	10090-10096	NN	denotes	strain
T3060	10085-10089	DT	denotes	this
T3059	10082-10084	IN	denotes	in
T3058	10070-10081	NNS	denotes	pseudogenes
T3057	10063-10066	MD	denotes	may
T3056	10053-10056	CD	denotes	two
T3055	10057-10062	NNS	denotes	genes
T3054	10047-10052	DT	denotes	these
T3053	10045-10046	:	denotes	;
T3052	10034-10045	NN	denotes	termination
T3051	10024-10033	JJ	denotes	premature
T3050	10020-10023	CC	denotes	and
T3049	10013-10019	NNS	denotes	shifts
T3048	10007-10012	NN	denotes	frame
T3047	10000-10006	VBP	denotes	create
T3046	9995-9999	WDT	denotes	that
T3045	9985-9994	NNS	denotes	deletions
T3042	9956-9964	NN	denotes	missense
T3041	9965-9974	NNS	denotes	mutations
T3040	9947-9955	JJ	denotes	numerous
T3039	10067-10069	VB	denotes	be
T3038	9935-9937	,	denotes	,
T3037	9927-9935	NN	denotes	Tas2r117
T3036	9923-9926	CC	denotes	and
T3035	9914-9922	NN	denotes	Tas2r103
T3034	9912-9914	,	denotes	,
T3033	9937-9946	VBD	denotes	contained
T3032	9902-9904	NN	denotes	D2
T3031	9905-9912	NNS	denotes	alleles
T3030	9898-9901	CD	denotes	Two
T3029	9897-10097	sentence	denotes	Two D2 alleles, Tas2r103 and Tas2r117, contained numerous missense mutations and small deletions that create frame shifts and premature termination; these two genes may be pseudogenes in this strain.
T3028	9896-9897	.	denotes	.
T3027	9892-9896	NNS	denotes	mice
T3026	9889-9891	NN	denotes	D2
T3025	9886-9888	IN	denotes	in
T3024	9875-9877	VBZ	denotes	is
T3023	9869-9874	NN	denotes	Tas2r
T3022	9864-9868	DT	denotes	this
T3021	9878-9885	VBN	denotes	deleted
T3020	9859-9863	IN	denotes	that
T3019	9848-9858	VBG	denotes	suggesting
T3018	9846-9848	,	denotes	,
T3017	9845-9846	-RRB-	denotes	)
T3016	9844-9845	CD	denotes	2
T3015	9828-9838	JJ	denotes	Additional
T3014	9839-9843	NN	denotes	file
T3013	9827-9828	-LRB-	denotes	(
T3012	9810-9826	NNS	denotes	oligonucleotides
T3011	9807-9809	IN	denotes	of
T3010	9801-9806	NNS	denotes	pairs
T3009	9797-9800	CD	denotes	two
T3008	9794-9796	IN	denotes	of
T3007	9787-9793	DT	denotes	either
T3006	9781-9786	VBG	denotes	using
T3005	9779-9780	-RRB-	denotes	)
T3004	9778-9779	CD	denotes	5
T3003	9771-9777	NN	denotes	Figure
T3002	9770-9771	-LRB-	denotes	(
T3001	9758-9765	JJ	denotes	genomic
T3000	9766-9769	NN	denotes	DNA
T2999	9755-9757	NN	denotes	D2
T2998	9750-9754	IN	denotes	from
T2997	9737-9739	VB	denotes	be
T2996	9733-9736	RB	denotes	not
T2995	9727-9732	MD	denotes	could
T2994	9725-9727	,	denotes	,
T2993	9717-9725	NN	denotes	Tas2r120
T2992	9715-9717	,	denotes	,
T2991	9740-9749	VBN	denotes	amplified
T2990	9710-9715	JJ	denotes	third
T2989	9708-9709	DT	denotes	A
T2988	9707-9897	sentence	denotes	A third, Tas2r120, could not be amplified from D2 genomic DNA (Figure 5) using either of two pairs of oligonucleotides (Additional file 2), suggesting that this Tas2r is deleted in D2 mice.
T2987	9706-9707	.	denotes	.
T2986	9705-9706	-RRB-	denotes	)
T2985	9696-9699	RB	denotes	not
T2984	9691-9695	NNS	denotes	data
T2983	9700-9705	VBN	denotes	shown
T2982	9690-9691	-LRB-	denotes	(
T2981	9679-9683	NN	denotes	acid
T2980	9673-9678	NN	denotes	amino
T2979	9684-9689	NN	denotes	level
T2978	9669-9672	DT	denotes	the
T2977	9666-9668	IN	denotes	at
T2976	9658-9665	NNS	denotes	strains
T2975	9651-9657	IN	denotes	across
T2974	9641-9650	JJ	denotes	identical
T2973	9634-9636	,	denotes	,
T2972	9626-9634	NN	denotes	Tas2r124
T2971	9622-9625	CC	denotes	and
T2970	9613-9621	NN	denotes	Tas2r106
T2969	9611-9613	,	denotes	,
T2968	9603-9611	VBN	denotes	examined
T2967	9589-9594	NN	denotes	Tas2r
T2966	9583-9584	HYPH	denotes	-
T2965	9584-9588	CD	denotes	four
T2964	9577-9583	CD	denotes	twenty
T2963	9595-9602	NNS	denotes	alleles
T2962	9573-9576	DT	denotes	the
T2961	9570-9572	IN	denotes	of
T2960	9566-9569	CD	denotes	two
T2959	9561-9565	RB	denotes	only
T2958	9636-9640	VBD	denotes	were
T2957	9556-9560	IN	denotes	that
T2956	9532-9534	NN	denotes	D2
T2955	9528-9531	CC	denotes	and
T2954	9535-9546	NNS	denotes	orthologues
T2953	9525-9527	NN	denotes	B6
T2952	9522-9524	IN	denotes	of
T2951	9512-9521	NNS	denotes	sequences
T2950	9508-9511	DT	denotes	the
T2949	9505-9507	IN	denotes	of
T2948	9547-9555	VBD	denotes	revealed
T2947	9493-9504	NNS	denotes	Comparisons
T2946	9492-9707	sentence	denotes	Comparisons of the sequences of B6 and D2 orthologues revealed that only two of the twenty-four Tas2r alleles examined, Tas2r106 and Tas2r124, were identical across strains at the amino acid level (data not shown).
T2945	9491-9492	.	denotes	.
T2944	9482-9491	VBN	denotes	sequenced
T2943	9478-9481	CC	denotes	and
T2942	9470-9477	NNS	denotes	vectors
T2941	9462-9469	NN	denotes	cloning
T2940	9457-9461	IN	denotes	into
T2939	9442-9446	VBD	denotes	were
T2938	9447-9456	VBN	denotes	subcloned
T2937	9433-9441	NNS	denotes	products
T2936	9429-9432	NN	denotes	PCR
T2935	9428-9492	sentence	denotes	PCR products were subcloned into cloning vectors and sequenced.
T2934	9427-9428	.	denotes	.
T2933	9416-9423	JJ	denotes	genomic
T2932	9424-9427	NN	denotes	DNA
T2931	9413-9415	NN	denotes	D2
T2930	9408-9412	IN	denotes	from
T2929	9392-9398	NN	denotes	coding
T2928	9386-9391	NN	denotes	Tas2r
T2927	9399-9407	NN	denotes	sequence
T2926	9381-9385	DT	denotes	each
T2925	9368-9370	PRP	denotes	we
T2924	9366-9368	,	denotes	,
T2923	9360-9366	NNS	denotes	oligos
T2922	9354-9359	DT	denotes	these
T2921	9371-9380	VBD	denotes	amplified
T2920	9348-9353	VBG	denotes	Using
T2919	9347-9428	sentence	denotes	Using these oligos, we amplified each Tas2r coding sequence from D2 genomic DNA.
T2918	9346-9347	.	denotes	.
T2917	9345-9346	-RRB-	denotes	]
T2916	9344-9345	CD	denotes	2
T2915	9339-9343	NN	denotes	file
T2914	9328-9338	JJ	denotes	Additional
T2913	9324-9327	VB	denotes	see
T2912	9323-9324	-LRB-	denotes	[
T2911	9310-9316	JJ	denotes	intact
T2910	9317-9322	NN	denotes	Tas2r
T2909	9305-9309	DT	denotes	each
T2908	9302-9304	IN	denotes	of
T2907	9286-9292	NN	denotes	coding
T3279	11732-11742	JJ	denotes	diagnostic
T3278	11755-11767	NN	denotes	endonuclease
T3277	11729-11731	DT	denotes	no
T3276	11777-11787	VBN	denotes	identified
T3275	11723-11728	WRB	denotes	where
T3274	11721-11722	-RRB-	denotes	)
T3273	11713-11721	NN	denotes	Tas2r110
T3272	11709-11712	CC	denotes	and
T3271	11700-11708	NN	denotes	Tas2r114
T3270	11698-11700	,	denotes	,
T3269	11690-11698	NN	denotes	Tas2r104
T3268	11689-11690	-LRB-	denotes	(
T3267	11683-11688	NNS	denotes	genes
T3266	11677-11682	CD	denotes	three
T3265	11665-11668	RB	denotes	not
T3264	11661-11664	VBD	denotes	did
T3263	11669-11676	VB	denotes	analyze
T3262	11658-11660	PRP	denotes	We
T3261	11657-11788	sentence	denotes	We did not analyze three genes (Tas2r104, Tas2r114 and Tas2r110) where no diagnostic restriction endonuclease could be identified.
T2906	9293-9301	NN	denotes	sequence
T2905	9282-9285	DT	denotes	the
T2904	9273-9281	VBG	denotes	flanking
T2903	9265-9272	NNS	denotes	regions
T2902	9254-9264	JJ	denotes	non-coding
T2901	9251-9253	IN	denotes	to
T2900	9234-9250	NNS	denotes	oligonucleotides
T2899	9225-9233	VBD	denotes	designed
T2898	9222-9224	PRP	denotes	We
T2897	9221-9347	sentence	denotes	We designed oligonucleotides to non-coding regions flanking the coding sequence of each intact Tas2r [see Additional file 2].
T2896	9220-9221	.	denotes	.
T2895	9219-9220	-RRB-	denotes	)
T2894	9218-9219	CD	denotes	4
T2893	9211-9217	NN	denotes	Figure
T2892	9210-9211	-LRB-	denotes	(
T2891	9208-9209	-RRB-	denotes	]
T2890	9206-9208	CD	denotes	19
T2889	9205-9206	-LRB-	denotes	[
T2888	9200-9204	NNS	denotes	mice
T2887	9197-9199	NN	denotes	B6
T2886	9194-9196	IN	denotes	of
T2885	9184-9185	CD	denotes	6
T2884	9173-9183	NN	denotes	chromosome
T2883	9166-9172	JJ	denotes	distal
T2882	9186-9193	NN	denotes	cluster
T2881	9162-9165	DT	denotes	the
T2880	9159-9161	IN	denotes	in
T2879	9143-9147	VBN	denotes	been
T2878	9138-9142	VBP	denotes	have
T2877	9136-9138	,	denotes	,
T2876	9119-9124	NN	denotes	Tas2r
T2875	9110-9118	JJ	denotes	apparent
T2874	9125-9136	NNS	denotes	pseudogenes
T2873	9104-9109	CD	denotes	three
T2872	9099-9103	IN	denotes	with
T2871	9093-9098	IN	denotes	along
T2870	9091-9093	,	denotes	,
T2869	9148-9158	VBN	denotes	identified
T2868	9078-9084	JJ	denotes	intact
T2867	9085-9091	NNS	denotes	Tas2rs
T2866	9072-9073	HYPH	denotes	-
T2865	9073-9077	CD	denotes	four
T2864	9066-9072	CD	denotes	Twenty
T2863	9065-9221	sentence	denotes	Twenty-four intact Tas2rs, along with three apparent Tas2r pseudogenes, have been identified in the distal chromosome 6 cluster of B6 mice [19] (Figure 4).
T2862	9064-9065	.	denotes	.
T2861	9041-9054	NN	denotes	insensitivity
T2860	9035-9040	NN	denotes	taste
T2859	9030-9034	NN	denotes	QHCl
T2858	9055-9064	NN	denotes	phenotype
T2857	9026-9029	DT	denotes	the
T2856	9021-9025	IN	denotes	with
T2855	9005-9010	MD	denotes	would
T2854	8996-8998	NN	denotes	D2
T2853	8989-8995	JJ	denotes	single
T2852	8999-9004	NN	denotes	Tas2r
T2851	8987-8988	DT	denotes	a
T2850	8984-8986	IN	denotes	of
T2849	8968-8974	VBG	denotes	coding
T2848	8975-8983	NN	denotes	sequence
T2847	8964-8967	DT	denotes	the
T2846	8957-8963	IN	denotes	within
T2845	8948-8956	NN	denotes	mutation
T2844	8945-8947	CC	denotes	or
T2843	8936-8944	NN	denotes	deletion
T2842	9011-9020	VB	denotes	correlate
T2841	8931-8935	IN	denotes	that
T2840	8920-8930	NN	denotes	likelihood
T2839	8916-8919	DT	denotes	the
T2838	8913-8915	IN	denotes	on
T2837	8895-8904	RB	denotes	initially
T2836	8892-8894	PRP	denotes	we
T2835	8890-8892	,	denotes	,
T2834	8877-8890	NNS	denotes	possibilities
T2833	8871-8876	JJ	denotes	valid
T2832	8865-8867	TO	denotes	to
T2831	8859-8864	DT	denotes	these
T2830	8856-8858	IN	denotes	of
T2829	8868-8870	VB	denotes	be
T2828	8850-8855	CD	denotes	three
T2827	8846-8849	DT	denotes	all
T2741	8446-8448	VBZ	denotes	is
T2740	8428-8429	LS	denotes	1
T2739	8427-8428	-LRB-	denotes	(
T2738	8425-8427	:	denotes	:
T2737	8403-8409	JJ	denotes	likely
T2736	8410-8425	NNS	denotes	characteristics
T2735	8397-8402	CD	denotes	three
T2734	8394-8396	IN	denotes	of
T2733	8390-8393	CD	denotes	one
T2732	8376-8381	MD	denotes	would
T2731	8364-8369	NN	denotes	Tas2r
T2730	8362-8363	-RRB-	denotes	)
T2729	8358-8362	JJR	denotes	more
T2728	8355-8357	CC	denotes	or
T2727	8354-8355	-LRB-	denotes	(
T2726	8370-8375	NNS	denotes	genes
T2725	8350-8353	CD	denotes	one
T2724	8382-8389	VB	denotes	exhibit
T2723	8345-8349	IN	denotes	that
T2722	8782-8789	VBZ	denotes	affects
T2721	8331-8336	MD	denotes	would
T2720	8328-8330	PRP	denotes	we
T2719	8326-8328	,	denotes	,
T2718	8311-8322	NN	denotes	sensitivity
T2717	8305-8310	NN	denotes	taste
T2716	8300-8304	NN	denotes	QHCl
T2715	8298-8299	CD	denotes	6
T2714	8287-8297	NN	denotes	chromosome
T2713	8323-8326	NN	denotes	QTL
T2712	8283-8286	DT	denotes	the
T2711	8337-8344	VB	denotes	predict
T2710	8265-8266	-RRB-	denotes	)
T2709	8261-8265	JJR	denotes	more
T2708	8258-8260	CC	denotes	or
T2707	8257-8258	-LRB-	denotes	(
T2706	8267-8273	NNS	denotes	Tas2rs
T2705	8253-8256	CD	denotes	one
T2704	8274-8282	VBP	denotes	underlie
T2703	8250-8252	IN	denotes	If
T2702	8249-8824	sentence	denotes	If one (or more) Tas2rs underlie the chromosome 6 QHCl taste sensitivity QTL, we would predict that one (or more) Tas2r genes would exhibit one of three likely characteristics: (1) A Tas2r allele is a pseudogene, or is deleted, in D2 (QHCL-insensitive), but not B6 (QHCl-sensitive), mice; (2) Missense mutations in the single coding exon of a D2 Tas2r allele impact protein functions such as ligand binding or receptor coupling to downstream signaling cascades; (3) Mutations in noncoding or regulatory regions of a D2 Tas2r allele affects expression of the protein product.
T2701	8242-8249	NNS	denotes	alleles
T2700	8238-8241	NN	denotes	T2R
T3044	9979-9984	JJ	denotes	small
T3043	9975-9978	CC	denotes	and
T2456	7045-7050	RBS	denotes	least
T2455	7042-7044	RB	denotes	at
T2454	7039-7041	IN	denotes	of
T2453	7029-7038	NN	denotes	detection
T2452	7025-7028	DT	denotes	the
T2451	7022-7024	IN	denotes	in
T2450	7017-7021	NN	denotes	role
T2449	7011-7016	PRP$	denotes	their
T2448	7007-7010	CC	denotes	and
T2447	7005-7007	,	denotes	,
T2446	6991-6999	NN	denotes	receptor
T2445	7000-7005	NNS	denotes	cells
T2444	6985-6990	NN	denotes	taste
T2443	6982-6984	IN	denotes	in
T2442	6958-6970	VBN	denotes	demonstrated
T2441	6971-6981	NN	denotes	expression
T2440	6952-6957	PRP$	denotes	their
T2439	6950-6952	,	denotes	,
T2438	6937-6943	VBN	denotes	linked
T2437	6944-6950	NN	denotes	marker
T2436	6933-6936	DT	denotes	the
T2435	6930-6932	IN	denotes	to
T2434	6920-6929	NN	denotes	proximity
T2433	6914-6919	PRP$	denotes	their
T2432	6911-6913	IN	denotes	of
T2431	7085-7097	VBD	denotes	hypothesized
T2430	6903-6910	IN	denotes	Because
T2429	6902-7204	sentence	denotes	Because of their proximity to the linked marker, their demonstrated expression in taste receptor cells, and their role in the detection of at least some bitter-tasting compounds, we hypothesized that one or more of the 24 Tas2rs at this locus were responsible for the major QHCl taste sensitivity QTL.
T2428	6901-6902	.	denotes	.
T2427	6900-6901	-RRB-	denotes	)
T2426	6899-6900	CD	denotes	4
T2425	6890-6892	,	denotes	,
T2424	6889-6890	CD	denotes	3
T2423	6882-6888	NN	denotes	Figure
T2422	6892-6898	NN	denotes	Figure
T2421	6881-6882	-LRB-	denotes	(
T2420	6873-6880	NN	denotes	D6Mit13
T2419	6870-6872	IN	denotes	of
T2418	6865-6869	NN	denotes	side
T2417	6858-6864	DT	denotes	either
T2416	6855-6857	IN	denotes	on
T2415	6843-6845	NN	denotes	Mb
T2414	6839-6842	CD	denotes	1.2
T2413	6846-6854	NN	denotes	interval
T2412	6837-6838	DT	denotes	a
T2411	6830-6836	IN	denotes	within
T2410	6820-6829	VBN	denotes	clustered
T2409	6810-6813	VBP	denotes	are
T2408	6808-6809	-RRB-	denotes	)
T2407	6804-6808	NNS	denotes	T2Rs
T2406	6800-6803	DT	denotes	the
T2405	6793-6799	VBP	denotes	encode
T2404	6787-6792	WDT	denotes	which
T2403	6786-6787	-LRB-	denotes	(
T2402	6814-6819	VBN	denotes	found
T2401	6774-6779	NN	denotes	Tas2r
T2400	6780-6785	NNS	denotes	genes
T2399	6770-6773	DT	denotes	The
T2398	6769-6902	sentence	denotes	The Tas2r genes (which encode the T2Rs) are found clustered within a 1.2 Mb interval on either side of D6Mit13 (Figure 3, Figure 4).
T2397	6768-6769	.	denotes	.
T2396	6753-6758	NN	denotes	taste
T2395	6759-6768	NNS	denotes	receptors
T2394	6747-6748	HYPH	denotes	-
T2393	6748-6752	NN	denotes	type
T2392	6744-6747	NN	denotes	T2R
T2391	6740-6743	CC	denotes	and
T2390	6738-6740	,	denotes	,
T2389	6723-6724	HYPH	denotes	-
T2388	6724-6728	JJ	denotes	like
T2387	6717-6723	NN	denotes	lectin
T2386	6729-6738	NNS	denotes	receptors
T2385	6705-6711	NN	denotes	killer
T2384	6712-6716	NN	denotes	cell
T2383	6697-6704	JJ	denotes	natural
T2382	6695-6697	:	denotes	:
T2381	6678-6686	NN	denotes	receptor
T2380	6672-6677	JJ	denotes	large
T2379	6687-6695	NNS	denotes	families
T2378	6668-6671	CD	denotes	two
T2377	6665-6667	IN	denotes	of
T2376	6657-6664	NNS	denotes	members
T2375	6644-6649	WDT	denotes	which
T2374	6641-6643	IN	denotes	of
T2373	6634-6640	CD	denotes	eleven
T2372	6630-6633	IN	denotes	but
T2371	6650-6656	VBP	denotes	encode
T2370	6626-6629	DT	denotes	all
T2369	6624-6626	,	denotes	,
T2368	6619-6624	NNS	denotes	genes
T2367	6613-6618	JJ	denotes	known
T2366	6610-6612	IN	denotes	of
T2365	6603-6609	NN	denotes	number
T2364	6601-6602	DT	denotes	a
T2363	6592-6600	VBZ	denotes	contains
T2362	6585-6591	NN	denotes	region
T2361	6580-6584	DT	denotes	This
T2360	6579-6769	sentence	denotes	This region contains a number of known genes, all but eleven of which encode members of two large receptor families: natural killer cell lectin-like receptors, and T2R-type taste receptors.
T2359	6578-6579	.	denotes	.
T2358	6577-6578	-RRB-	denotes	)
T2357	6576-6577	CD	denotes	3
T2356	6569-6575	NN	denotes	Figure
T2355	6568-6569	-LRB-	denotes	(
T2354	6565-6567	NN	denotes	Mb
T2353	6556-6560	IN	denotes	than
T2352	6561-6564	CD	denotes	5.0
T2351	6551-6555	JJR	denotes	less
T2350	6542-6543	CD	denotes	6
T2349	6531-6541	NN	denotes	chromosome
T2348	6526-6530	NN	denotes	QHCl
T2347	6544-6547	NN	denotes	QTL
T2346	6522-6525	DT	denotes	the
T2345	6519-6521	IN	denotes	of
T2344	6514-6518	NN	denotes	size
T2343	6510-6513	DT	denotes	the
T2342	6508-6510	,	denotes	,
T2341	6492-6498	NN	denotes	marker
T2340	6499-6508	NNS	denotes	positions
T2339	6486-6491	DT	denotes	these
T2338	6483-6485	IN	denotes	on
T2337	6548-6550	VBZ	denotes	is
T2336	6477-6482	VBN	denotes	Based
T2335	6476-6579	sentence	denotes	Based on these marker positions, the size of the QHCl chromosome 6 QTL is less than 5.0 Mb (Figure 3).
T2334	6475-6476	.	denotes	.
T2333	6466-6468	NN	denotes	B6
T2332	6459-6465	JJ	denotes	public
T2331	6469-6475	NN	denotes	genome
T2330	6455-6458	DT	denotes	the
T2329	6452-6454	IN	denotes	of
T2328	6441-6445	CD	denotes	2004
T2327	6439-6441	,	denotes	,
T2326	6436-6439	NNP	denotes	May
T2325	6446-6451	NN	denotes	build
T2324	6432-6435	DT	denotes	the
T2323	6429-6431	IN	denotes	on
T2322	6423-6428	VBN	denotes	based
T2321	6416-6422	FW	denotes	silico
T2826	8905-8912	VBD	denotes	focused
T2825	8832-8834	PRP	denotes	we
T2824	8835-8845	VBD	denotes	considered
T2823	8825-8831	IN	denotes	Though
T2822	8824-9065	sentence	denotes	Though we considered all three of these to be valid possibilities, we initially focused on the likelihood that deletion or mutation within the coding sequence of a single D2 Tas2r would correlate with the QHCl taste insensitivity phenotype.
T2821	8823-8824	.	denotes	.
T2820	8808-8815	NN	denotes	protein
T2819	8816-8823	NN	denotes	product
T2818	8804-8807	DT	denotes	the
T2817	8801-8803	IN	denotes	of
T2816	8790-8800	NN	denotes	expression
T2815	8769-8774	NN	denotes	Tas2r
T2814	8766-8768	NN	denotes	D2
T2813	8775-8781	NN	denotes	allele
T2812	8764-8765	DT	denotes	a
T2811	8761-8763	IN	denotes	of
T2810	8742-8752	JJ	denotes	regulatory
T2809	8739-8741	CC	denotes	or
T2808	8753-8760	NNS	denotes	regions
T2807	8729-8738	JJ	denotes	noncoding
T2806	8726-8728	IN	denotes	in
T2805	8716-8725	NNS	denotes	Mutations
T2804	8714-8715	-RRB-	denotes	)
T2803	8713-8714	LS	denotes	3
T2802	8712-8713	-LRB-	denotes	(
T2801	8710-8711	:	denotes	;
T2800	8692-8701	NN	denotes	signaling
T2799	8702-8710	NNS	denotes	cascades
T2798	8681-8691	JJ	denotes	downstream
T2797	8678-8680	IN	denotes	to
T2796	8669-8677	NN	denotes	coupling
T2795	8660-8668	NN	denotes	receptor
T2794	8657-8659	CC	denotes	or
T2793	8649-8656	NN	denotes	binding
T2792	8642-8648	NN	denotes	ligand
T2791	8639-8641	IN	denotes	as
T2790	8634-8638	JJ	denotes	such
T2789	8624-8633	NNS	denotes	functions
T2788	8616-8623	NN	denotes	protein
T2787	8596-8601	NN	denotes	Tas2r
T2786	8593-8595	NN	denotes	D2
T2785	8602-8608	NN	denotes	allele
T2784	8591-8592	DT	denotes	a
T2783	8588-8590	IN	denotes	of
T2782	8576-8582	VBG	denotes	coding
T2781	8569-8575	JJ	denotes	single
T2780	8583-8587	NN	denotes	exon
T2779	8565-8568	DT	denotes	the
T2778	8562-8564	IN	denotes	in
T2777	8552-8561	NNS	denotes	mutations
T2776	8543-8551	NN	denotes	Missense
T2775	8541-8542	-RRB-	denotes	)
T2774	8609-8615	VBP	denotes	impact
T2773	8540-8541	LS	denotes	2
T2772	8539-8540	-LRB-	denotes	(
T2771	8537-8538	:	denotes	;
T2770	8531-8533	,	denotes	,
T2769	8530-8531	-RRB-	denotes	)
T2768	8520-8521	HYPH	denotes	-
T2767	8516-8520	NN	denotes	QHCl
T2766	8521-8530	JJ	denotes	sensitive
T2765	8515-8516	-LRB-	denotes	(
T2764	8512-8514	NN	denotes	B6
T2763	8508-8511	RB	denotes	not
T2762	8504-8507	CC	denotes	but
T2761	8502-8504	,	denotes	,
T2760	8501-8502	-RRB-	denotes	)
T2759	8489-8490	HYPH	denotes	-
T2758	8485-8489	NN	denotes	QHCL
T2757	8490-8501	JJ	denotes	insensitive
T2756	8484-8485	-LRB-	denotes	(
T2755	8533-8537	NNS	denotes	mice
T2754	8481-8483	NN	denotes	D2
T2753	8478-8480	IN	denotes	in
T2752	8476-8478	,	denotes	,
T2751	8469-8476	VBN	denotes	deleted
T2750	8466-8468	VBZ	denotes	is
T2749	8463-8465	CC	denotes	or
T2748	8461-8463	,	denotes	,
T2747	8451-8461	NN	denotes	pseudogene
T2746	8449-8450	DT	denotes	a
T2745	8433-8438	NN	denotes	Tas2r
T2744	8439-8445	NN	denotes	allele
T2743	8431-8432	NN	denotes	A
T2742	8429-8430	-RRB-	denotes	)
T2320	6413-6415	FW	denotes	in
T2319	6399-6402	VBD	denotes	was
T2318	6397-6399	,	denotes	,
T2317	6389-6397	NN	denotes	D6Mit374
T2316	6378-6388	NN	denotes	D6Mit61and
T2315	6376-6378	,	denotes	,
T2314	6360-6368	JJ	denotes	unlinked
T2313	6352-6359	JJS	denotes	closest
T2312	6348-6351	CD	denotes	two
T2311	6369-6376	NNS	denotes	markers
T2310	6344-6347	DT	denotes	the
T2309	6340-6343	CC	denotes	and
T2308	6338-6340	,	denotes	,
T2307	6331-6338	NN	denotes	D6Mit13
T2306	6329-6331	,	denotes	,
T2305	6316-6322	VBN	denotes	linked
T2304	6309-6315	JJ	denotes	single
T2303	6323-6329	NN	denotes	marker
T2302	6305-6308	DT	denotes	the
T2301	6302-6304	IN	denotes	of
T2300	6403-6412	VBN	denotes	performed
T2299	6294-6301	NN	denotes	mapping
T2298	6285-6293	JJ	denotes	Physical
T2297	6284-6476	sentence	denotes	Physical mapping of the single linked marker, D6Mit13, and the two closest unlinked markers, D6Mit61and D6Mit374, was performed in silico based on the May, 2004 build of the public B6 genome.
T2296	6283-6284	.	denotes	.
T2295	6275-6283	NN	denotes	D6Mit374
T2294	6271-6274	CC	denotes	and
T2293	6263-6270	NN	denotes	D6Mit61
T2292	6255-6262	IN	denotes	between
T2291	6248-6254	NN	denotes	region
T2290	6244-6247	DT	denotes	the
T2289	6241-6243	IN	denotes	to
T2288	6223-6229	RB	denotes	likely
T2287	6218-6222	RBS	denotes	most
T2286	6230-6240	VBN	denotes	restricted
T2285	6215-6217	VBZ	denotes	is
T2284	6211-6214	CC	denotes	but
T2283	6209-6211	,	denotes	,
T2282	6201-6209	NN	denotes	D6Mit374
T2281	6197-6200	CC	denotes	and
T2280	6188-6196	NN	denotes	D6Mit254
T2279	6180-6187	IN	denotes	between
T2278	6175-6179	VBZ	denotes	lies
T2277	6170-6174	WDT	denotes	that
T2276	6168-6169	CD	denotes	6
T2275	6157-6167	NN	denotes	chromosome
T2274	6151-6156	NN	denotes	mouse
T2273	6148-6150	IN	denotes	of
T2272	6140-6147	NN	denotes	portion
T2271	6135-6139	DT	denotes	that
T2270	6132-6134	IN	denotes	as
T2269	6109-6123	RB	denotes	conservatively
T2268	6106-6108	VB	denotes	be
T2267	6102-6105	MD	denotes	can
T2266	6089-6092	NN	denotes	QTL
T2265	6093-6101	NN	denotes	interval
T2264	6084-6088	DT	denotes	this
T2263	6082-6084	,	denotes	,
T2262	6124-6131	VBN	denotes	defined
T2261	6073-6082	RB	denotes	Therefore
T2260	6072-6284	sentence	denotes	Therefore, this QTL interval can be conservatively defined as that portion of mouse chromosome 6 that lies between D6Mit254 and D6Mit374, but is most likely restricted to the region between D6Mit61 and D6Mit374.
T2259	6071-6072	.	denotes	.
T2258	6063-6067	NN	denotes	QHCl
T2257	6068-6071	NN	denotes	QTL
T2256	6059-6062	DT	denotes	the
T2255	6056-6058	IN	denotes	to
T2254	6047-6055	JJ	denotes	unlinked
T2253	6036-6043	NN	denotes	D6Mit61
T2252	6044-6046	VBZ	denotes	is
T2251	6031-6035	IN	denotes	that
T2250	6020-6030	VBG	denotes	indicating
T2249	6018-6020	,	denotes	,
T2248	6017-6018	-RRB-	denotes	]
T2247	6014-6015	,	denotes	,
T2246	6012-6014	CD	denotes	39
T2245	6015-6017	CD	denotes	40
T2244	6011-6012	-LRB-	denotes	[
T2243	6003-6010	NN	denotes	D6Mit61
T2242	5999-6002	IN	denotes	for
T2241	5987-5989	NN	denotes	B6
T1968	4448-4459	JJ	denotes	significant
T1967	4460-4464	NNS	denotes	QTLs
T1966	4445-4447	DT	denotes	No
T1965	4444-4651	sentence	denotes	No significant QTLs were identified for DB taste sensitivity, although several associations with markers on chromosomes 2,8 and 12 were "suggestive" (LRS > 9.4, genome-wide p = 0.65; see Additional File 1).
T1964	4443-4444	.	denotes	.
T1963	4442-4443	-RRB-	denotes	)
T1962	4441-4442	-RRB-	denotes	]
T1961	4438-4439	-LRB-	denotes	[
T1960	4434-4438	CD	denotes	0.30
T1959	4426-4433	NN	denotes	version
T1958	4439-4441	CD	denotes	38
T1957	4425-4426	-LRB-	denotes	(
T1956	4421-4424	NNP	denotes	QTX
T1955	4413-4420	NNP	denotes	Manager
T1954	4409-4412	NNP	denotes	Map
T1953	4403-4408	VBG	denotes	using
T1952	4389-4392	VBD	denotes	was
T1951	4393-4402	VBN	denotes	conducted
T1950	4380-4388	NN	denotes	analysis
T1949	4372-4379	NN	denotes	Linkage
T1948	4371-4444	sentence	denotes	Linkage analysis was conducted using Map Manager QTX (version 0.30[38]).
T1947	4364-4371	NN	denotes	mapping
T1946	4360-4363	NN	denotes	QTL
T1841	4357-4358	.	denotes	.
T1840	4356-4357	-RRB-	denotes	)
T1839	4354-4356	CD	denotes	1D
T1838	4353-4354	SYM	denotes	–
T1837	4343-4350	NNS	denotes	Figures
T1836	4351-4353	CD	denotes	1B
T1835	4342-4343	-LRB-	denotes	(
T1834	4336-4341	FW	denotes	versa
T1833	4331-4335	FW	denotes	vice
T2484	7203-7204	.	denotes	.
T2483	7188-7199	NN	denotes	sensitivity
T2482	7182-7187	NN	denotes	taste
T2481	7177-7181	NN	denotes	QHCl
T2480	7171-7176	JJ	denotes	major
T2479	7200-7203	NN	denotes	QTL
T2478	7167-7170	DT	denotes	the
T2477	7163-7166	IN	denotes	for
T2476	7151-7162	JJ	denotes	responsible
T2475	7140-7145	NN	denotes	locus
T2474	7135-7139	DT	denotes	this
T2473	7132-7134	IN	denotes	at
T2472	7122-7124	CD	denotes	24
T2471	7125-7131	NNS	denotes	Tas2rs
T2470	7118-7121	DT	denotes	the
T2469	7115-7117	IN	denotes	of
T2468	7110-7114	JJR	denotes	more
T2467	7107-7109	CC	denotes	or
T2466	7103-7106	CD	denotes	one
T2465	7146-7150	VBD	denotes	were
T2464	7098-7102	IN	denotes	that
T2463	7082-7084	PRP	denotes	we
T2462	7080-7082	,	denotes	,
T2461	7062-7063	HYPH	denotes	-
T2460	7063-7070	VBG	denotes	tasting
T2459	7056-7062	JJ	denotes	bitter
T2458	7051-7055	DT	denotes	some
T2457	7071-7080	NNS	denotes	compounds
T1832	4327-4330	CC	denotes	and
T1831	4325-4327	,	denotes	,
T1830	4323-4325	NN	denotes	DB
T1829	4320-4322	IN	denotes	to
T1828	4308-4319	JJ	denotes	insensitive
T1827	4297-4307	RB	denotes	relatively
T1826	4288-4292	NN	denotes	QHCl
T1825	4285-4287	IN	denotes	to
T1824	4275-4284	JJ	denotes	sensitive
T1823	4268-4274	RB	denotes	highly
T1822	4260-4267	NNS	denotes	strains
T1821	4255-4259	DT	denotes	some
T1820	4253-4255	:	denotes	:
T1819	4243-4245	JJ	denotes	RI
T1818	4246-4253	NNS	denotes	strains
T1817	4237-4242	DT	denotes	these
T1816	4230-4236	IN	denotes	across
T1815	4216-4229	RB	denotes	independently
T1814	4293-4296	VBP	denotes	are
T1813	4193-4198	NN	denotes	taste
T1812	4190-4192	NN	denotes	DB
T1811	4186-4189	CC	denotes	and
T1810	4199-4210	NN	denotes	sensitivity
T1809	4181-4185	NN	denotes	QHCl
T1808	4179-4181	,	denotes	,
T1807	4211-4215	VBP	denotes	vary
T1806	4172-4179	RB	denotes	However
T1805	4171-4358	sentence	denotes	However, QHCl and DB taste sensitivity vary independently across these RI strains: some strains highly sensitive to QHCl are relatively insensitive to DB, and vice versa (Figures 1B–1D).
T1804	4170-4171	.	denotes	.
T1803	4169-4170	-RRB-	denotes	)
T1802	4168-4169	CD	denotes	1
T1801	4160-4161	:	denotes	;
T1800	4158-4160	CD	denotes	1D
T1799	4157-4158	SYM	denotes	–
T1798	4155-4157	CD	denotes	1B
T1797	4147-4154	NNS	denotes	Figures
T1796	4162-4167	NN	denotes	Table
T1795	4146-4147	-LRB-	denotes	(
T1794	4129-4138	JJ	denotes	dependent
T1793	4115-4128	NN	denotes	concentration
T1792	4139-4145	NN	denotes	manner
T1791	4113-4114	DT	denotes	a
T1790	4110-4112	IN	denotes	in
T1789	4102-4109	NNS	denotes	stimuli
T1788	4097-4101	DT	denotes	both
T1787	4079-4088	RB	denotes	typically
T1786	4074-4078	RB	denotes	also
T1785	4089-4096	VBD	denotes	avoided
T1784	4069-4073	NNS	denotes	mice
T1783	4065-4068	NN	denotes	BXD
T1782	4064-4171	sentence	denotes	BXD mice also typically avoided both stimuli in a concentration dependent manner (Figures 1B–1D; Table 1).
T1781	4063-4064	.	denotes	.
T1780	4052-4056	JJ	denotes	same
T1779	4057-4063	NN	denotes	manner
T1778	4048-4051	DT	denotes	the
T1777	4045-4047	IN	denotes	in
T1776	4035-4038	NN	denotes	BXD
T1775	4039-4044	NNS	denotes	lines
T1774	4032-4034	CD	denotes	17
T1773	4027-4031	IN	denotes	from
T1772	4022-4026	NNS	denotes	mice
T1771	4010-4014	RB	denotes	next
T2158	5585-5590	NN	denotes	event
T2157	5561-5566	RBS	denotes	least
T2156	5567-5570	CD	denotes	one
T2155	5558-5560	RB	denotes	at
T2154	5549-5554	EX	denotes	there
T2153	5542-5548	VBN	denotes	tested
T2152	5533-5535	JJ	denotes	RI
T2151	5530-5532	CD	denotes	17
T2150	5536-5541	NNS	denotes	lines
T2149	5526-5529	DT	denotes	the
T2148	5555-5557	VBZ	denotes	is
T2147	5519-5525	IN	denotes	Across
T2146	5518-5706	sentence	denotes	Across the 17 RI lines tested there is at least one recombination event between D6Mit13 and either D6Mit254 (and D6Mit194, the physical position of which is not well defined) or D6Mit374.
T2145	5517-5518	.	denotes	.
T2144	5509-5517	NN	denotes	D6Mit374
T2143	5502-5508	NN	denotes	marker
T2142	5495-5501	JJ	denotes	distal
T2141	5492-5494	VBZ	denotes	is
T2140	5489-5491	IN	denotes	as
T2139	5487-5489	,	denotes	,
T2138	5479-5483	NN	denotes	QHCl
T2137	5484-5487	NN	denotes	QTL
T2136	5475-5478	DT	denotes	the
T2135	5472-5474	IN	denotes	to
T2134	5463-5471	JJ	denotes	unlinked
T2133	5450-5458	NN	denotes	D6Mit194
T2132	5446-5449	CC	denotes	and
T2131	5459-5462	VBP	denotes	are
T2130	5429-5436	NNS	denotes	markers
T2129	5420-5428	JJ	denotes	proximal
T2128	5437-5445	NN	denotes	D6Mit254
T2127	5411-5419	JJ	denotes	Adjacent
T2126	5410-5518	sentence	denotes	Adjacent proximal markers D6Mit254 and D6Mit194 are unlinked to the QHCl QTL, as is distal marker D6Mit374.
T2125	5409-5410	.	denotes	.
T2124	5408-5409	-RRB-	denotes	)
T2123	5407-5408	CD	denotes	3
T2122	5398-5400	,	denotes	,
T2121	5397-5398	CD	denotes	2
T2120	5391-5396	NN	denotes	Table
T2118	5390-5391	-LRB-	denotes	(
T2066	4862-4863	CD	denotes	3
T2065	4859-4861	IN	denotes	at
T2064	4857-4858	:	denotes	;
T2063	4856-4857	-RRB-	denotes	)
T2062	4854-4856	CD	denotes	2A
T2061	4847-4853	NN	denotes	Figure
T2060	4846-4847	-LRB-	denotes	(
T2059	4844-4845	CD	denotes	8
T2058	4833-4843	NN	denotes	chromosome
T2057	4830-4832	IN	denotes	on
T2056	4824-4825	-RRB-	denotes	)
T2055	4818-4819	SYM	denotes	=
T2054	4816-4817	NN	denotes	p
T2053	4810-4811	HYPH	denotes	-
T2052	4811-4815	JJ	denotes	wide
T2051	4804-4810	NN	denotes	genome
T2050	4802-4803	:	denotes	;
T2049	4796-4797	SYM	denotes	>
T2048	4798-4802	CD	denotes	11.4
T2047	4792-4795	NN	denotes	LRS
T2046	4820-4824	CD	denotes	0.65
T2045	4791-4792	-LRB-	denotes	(
T2044	4780-4790	JJ	denotes	suggestive
T2043	4778-4780	,	denotes	,
T2042	4772-4778	JJ	denotes	second
T2041	4770-4771	DT	denotes	a
T2040	4826-4829	NN	denotes	QTL
T2039	4765-4769	IN	denotes	with
T2038	4763-4765	,	denotes	,
T2037	4762-4763	CD	denotes	6
T2036	4751-4761	NN	denotes	chromosome
T2035	4748-4750	IN	denotes	on
T2034	4891-4895	VBD	denotes	were
T2033	4734-4737	VBD	denotes	was
T2032	4729-4733	NN	denotes	QHCl
T2031	4726-4728	NN	denotes	mM
T2030	4724-4725	CD	denotes	1
T2029	4721-4723	IN	denotes	to
T2028	4709-4720	NN	denotes	sensitivity
T2027	4705-4708	IN	denotes	for
T2026	4738-4747	VBN	denotes	indicated
T2025	4699-4700	-RRB-	denotes	)
T2024	4693-4694	SYM	denotes	=
T2023	4691-4692	NN	denotes	p
T2022	4685-4686	HYPH	denotes	-
T2021	4686-4690	JJ	denotes	wide
T2020	4679-4685	NN	denotes	genome
T2019	4677-4678	:	denotes	;
T2018	4671-4672	SYM	denotes	>
T2017	4673-4677	CD	denotes	20.5
T2016	4667-4670	NN	denotes	LRS
T2015	4695-4699	CD	denotes	0.05
T2014	4666-4667	-LRB-	denotes	(
T2013	4654-4665	JJ	denotes	significant
T2012	4701-4704	NN	denotes	QTL
T2011	4652-4653	DT	denotes	A
T2010	4651-4975	sentence	denotes	A significant (LRS > 20.5; genome-wide p = 0.05) QTL for sensitivity to 1 mM QHCl was indicated on chromosome 6, with a second, suggestive (LRS > 11.4; genome-wide p = 0.65) QTL on chromosome 8 (Figure 2A); at 3 mM QHCl, both of these QTL were suggestive (LRS > 10.9) but did not reach genome-wide significance (Figure 2B).
T2009	4650-4651	.	denotes	.
T2008	4649-4650	-RRB-	denotes	)
T2007	4648-4649	CD	denotes	1
T2006	4643-4647	NN	denotes	File
T2005	4632-4642	JJ	denotes	Additional
T2004	4626-4627	:	denotes	;
T2003	4620-4621	SYM	denotes	=
T2002	4622-4626	CD	denotes	0.65
T2001	4618-4619	NN	denotes	p
T2000	4612-4613	HYPH	denotes	-
T1999	4613-4617	JJ	denotes	wide
T1998	4606-4612	NN	denotes	genome
T1997	4604-4606	,	denotes	,
T1996	4599-4600	SYM	denotes	>
T1995	4601-4604	CD	denotes	9.4
T1994	4595-4598	NN	denotes	LRS
T1993	4628-4631	VB	denotes	see
T1992	4594-4595	-LRB-	denotes	(
T1991	4592-4593	''	denotes	"
T1990	4582-4592	JJ	denotes	suggestive
T1989	4581-4582	``	denotes	"
T1988	4573-4575	CD	denotes	12
T1987	4569-4572	CC	denotes	and
T1986	4567-4568	CD	denotes	8
T1985	4566-4567	,	denotes	,
T1984	4565-4566	CD	denotes	2
T1983	4553-4564	NNS	denotes	chromosomes
T1982	4550-4552	IN	denotes	on
T1981	4542-4549	NNS	denotes	markers
T1980	4537-4541	IN	denotes	with
T1979	4524-4536	NNS	denotes	associations
T1978	4516-4523	JJ	denotes	several
T1977	4576-4580	VBD	denotes	were
T1976	4507-4515	IN	denotes	although
T1975	4505-4507	,	denotes	,
T1974	4488-4493	NN	denotes	taste
T1973	4494-4505	NN	denotes	sensitivity
T1972	4485-4487	NN	denotes	DB
T1971	4481-4484	IN	denotes	for
T1970	4465-4469	VBD	denotes	were
T1969	4470-4480	VBN	denotes	identified
T2240	5990-5998	NN	denotes	genotype
T2239	5985-5986	DT	denotes	a
T2238	5980-5984	VBP	denotes	have
T2237	5976-5979	CC	denotes	but
T2236	5974-5976	,	denotes	,
T2235	5967-5974	NN	denotes	D6Mit13
T2234	5963-5966	IN	denotes	for
T2233	5954-5962	NN	denotes	genotype
T2232	5951-5953	NN	denotes	D2
T2231	5947-5950	CC	denotes	and
T2230	5945-5946	-RRB-	denotes	)
T2229	5943-5945	CD	denotes	1C
T2228	5936-5942	NN	denotes	Figure
T2227	5935-5936	-LRB-	denotes	(
T2226	5929-5934	NN	denotes	taste
T2225	5924-5928	NN	denotes	QHCl
T2224	5920-5923	IN	denotes	for
T2223	5907-5909	NN	denotes	D2
T2222	5901-5906	JJ	denotes	clear
T2221	5910-5919	NN	denotes	phenotype
T2220	5899-5900	DT	denotes	a
T2219	5891-5898	VBP	denotes	display
T2218	5883-5885	JJ	denotes	RI
T2217	5880-5882	CD	denotes	34
T2216	5879-5880	HYPH	denotes	-
T2215	5877-5879	NN	denotes	Ty
T2214	5876-5877	HYPH	denotes	/
T2213	5886-5890	NNS	denotes	mice
T2212	5873-5876	NN	denotes	BXD
T2211	5872-6072	sentence	denotes	BXD/Ty-34 RI mice display a clear D2 phenotype for QHCl taste (Figure 1C) and D2 genotype for D6Mit13, but have a B6 genotype for D6Mit61 [39,40], indicating that D6Mit61 is unlinked to the QHCl QTL.
T2210	5871-5872	.	denotes	.
T2209	5851-5858	NNP	denotes	Jackson
T2208	5859-5871	NNP	denotes	Laboratories
T2207	5847-5850	DT	denotes	the
T2206	5844-5846	IN	denotes	by
T2205	5835-5843	VBN	denotes	reported
T2204	5825-5828	NN	denotes	BXD
T2203	5829-5834	NNS	denotes	lines
T2202	5821-5824	DT	denotes	the
T2201	5818-5820	IN	denotes	of
T2200	5808-5817	NNS	denotes	genotypes
T2199	5803-5807	IN	denotes	from
T2198	5788-5791	VBD	denotes	was
T2197	5786-5788	,	denotes	,
T2196	5779-5786	NN	denotes	D6Mit13
T2195	5775-5778	CC	denotes	and
T2194	5766-5774	NN	denotes	D6Mit194
T2193	5758-5765	IN	denotes	between
T2192	5753-5757	VBZ	denotes	lies
T2191	5747-5752	WDT	denotes	which
T2190	5745-5747	,	denotes	,
T2189	5738-5745	NN	denotes	D6Mit61
T2188	5736-5738	,	denotes	,
T2187	5792-5802	VBN	denotes	identified
T2186	5721-5729	JJ	denotes	proximal
T2185	5710-5720	JJ	denotes	additional
T2184	5730-5736	NN	denotes	marker
T2183	5707-5709	DT	denotes	An
T2182	5706-5872	sentence	denotes	An additional proximal marker, D6Mit61, which lies between D6Mit194 and D6Mit13, was identified from genotypes of the BXD lines reported by the Jackson Laboratories.
T2181	5705-5706	.	denotes	.
T2180	5697-5705	NN	denotes	D6Mit374
T2179	5694-5696	CC	denotes	or
T2178	5692-5693	-RRB-	denotes	)
T2177	5685-5692	JJ	denotes	defined
T2176	5680-5684	RB	denotes	well
T2175	5676-5679	RB	denotes	not
T2174	5667-5672	WDT	denotes	which
T2173	5664-5666	IN	denotes	of
T2172	5673-5675	VBZ	denotes	is
T2171	5646-5654	JJ	denotes	physical
T2170	5655-5663	NN	denotes	position
T2169	5642-5645	DT	denotes	the
T2168	5640-5642	,	denotes	,
T2167	5632-5640	NN	denotes	D6Mit194
T2166	5628-5631	CC	denotes	and
T2165	5627-5628	-LRB-	denotes	(
T2164	5618-5626	NN	denotes	D6Mit254
T2163	5611-5617	CC	denotes	either
T2162	5607-5610	CC	denotes	and
T2161	5599-5606	NN	denotes	D6Mit13
T2160	5591-5598	IN	denotes	between
T2159	5571-5584	NN	denotes	recombination
T1522	9-14	NN	denotes	Taste
T1523	15-22	NN	denotes	testing
T1524	22-175	sentence	denotes	Previous efforts to map QTL for bitter taste have utilized consumption tests that may be confounded by the contributions of post-ingestive effects [29].
T1525	23-31	JJ	denotes	Previous
T1526	32-39	NNS	denotes	efforts
T1527	73-81	VBN	denotes	utilized
T1528	40-42	TO	denotes	to
T1529	43-46	VB	denotes	map
T1530	47-50	NN	denotes	QTL
T1531	51-54	IN	denotes	for
T1532	55-61	JJ	denotes	bitter
T1533	62-67	NN	denotes	taste
T1534	68-72	VBP	denotes	have
T1535	82-93	NN	denotes	consumption
T1536	94-99	NNS	denotes	tests
T1537	100-104	WDT	denotes	that
T1538	112-122	VBN	denotes	confounded
T1539	105-108	MD	denotes	may
T1540	109-111	VB	denotes	be
T1541	123-125	IN	denotes	by
T1542	126-129	DT	denotes	the
T1543	130-143	NNS	denotes	contributions
T1544	144-146	IN	denotes	of
T1545	147-161	JJ	denotes	post-ingestive
T1546	162-169	NNS	denotes	effects
T1547	170-171	-LRB-	denotes	[
T1548	171-173	CD	denotes	29
T1549	173-174	-RRB-	denotes	]
T1550	174-175	.	denotes	.
T1551	175-386	sentence	denotes	We used a modified brief-access lick test, which minimizes the contribution of such effects [29,37] to determine whether B6 and D2 mice display differences in taste sensitivity to the taste stimuli QHCl and DB.
T1552	176-178	PRP	denotes	We
T1553	179-183	VBD	denotes	used
T1554	184-185	DT	denotes	a
T1555	213-217	NN	denotes	test
T1556	186-194	VBN	denotes	modified
T1557	195-200	JJ	denotes	brief
T1558	201-207	NN	denotes	access
T1559	200-201	HYPH	denotes	-
T1560	208-212	NN	denotes	lick
T1561	217-219	,	denotes	,
T1562	219-224	WDT	denotes	which
T1563	225-234	VBZ	denotes	minimizes
T1564	235-238	DT	denotes	the
T1565	239-251	NN	denotes	contribution
T1566	252-254	IN	denotes	of
T1567	255-259	JJ	denotes	such
T1568	260-267	NNS	denotes	effects
T1569	268-269	-LRB-	denotes	[
T1570	272-274	CD	denotes	37
T1571	269-271	CD	denotes	29
T1572	271-272	,	denotes	,
T1573	274-275	-RRB-	denotes	]
T1574	276-278	TO	denotes	to
T1575	279-288	VB	denotes	determine
T1576	289-296	IN	denotes	whether
T1577	312-319	VBP	denotes	display
T1578	297-299	NN	denotes	B6
T1579	307-311	NNS	denotes	mice
T1580	300-303	CC	denotes	and
T1581	304-306	NN	denotes	D2
T1582	320-331	NNS	denotes	differences
T1583	332-334	IN	denotes	in
T1584	335-340	NN	denotes	taste
T1585	341-352	NN	denotes	sensitivity
T1586	353-355	IN	denotes	to
T1587	356-359	DT	denotes	the
T1588	366-373	NNS	denotes	stimuli
T1589	360-365	NN	denotes	taste
T1590	374-378	NN	denotes	QHCl
T1591	379-382	CC	denotes	and
T1592	383-385	NN	denotes	DB
T1593	385-386	.	denotes	.
T1594	386-606	sentence	denotes	After initially screening B6 and D2 mice to determine stimulus concentrations that were aversive but not saturating [47], we selected two ligand concentrations for each compound that best differentiated the two strains.
T1595	387-392	IN	denotes	After
T1596	512-520	VBD	denotes	selected
T1597	393-402	RB	denotes	initially
T1598	403-412	VBG	denotes	screening
T1599	413-415	NN	denotes	B6
T1600	423-427	NNS	denotes	mice
T1601	416-419	CC	denotes	and
T1602	420-422	NN	denotes	D2
T1603	428-430	TO	denotes	to
T1604	431-440	VB	denotes	determine
T1605	441-449	NN	denotes	stimulus
T1606	450-464	NNS	denotes	concentrations
T1607	465-469	WDT	denotes	that
T1608	470-474	VBD	denotes	were
T1609	475-483	JJ	denotes	aversive
T1610	484-487	CC	denotes	but
T1611	488-491	RB	denotes	not
T1612	492-502	VBG	denotes	saturating
T1613	503-504	-LRB-	denotes	[
T1614	504-506	CD	denotes	47
T1615	506-507	-RRB-	denotes	]
T1616	507-509	,	denotes	,
T1617	509-511	PRP	denotes	we
T1618	521-524	CD	denotes	two
T1619	532-546	NNS	denotes	concentrations
T1620	525-531	NN	denotes	ligand
T1621	547-550	IN	denotes	for
T1622	551-555	DT	denotes	each
T1623	556-564	NN	denotes	compound
T1624	565-569	WDT	denotes	that
T1625	575-589	VBD	denotes	differentiated
T1626	570-574	RBS	denotes	best
T1627	590-593	DT	denotes	the
T1628	598-605	NNS	denotes	strains
T1629	594-597	CD	denotes	two
T1630	605-606	.	denotes	.
T1631	606-725	sentence	denotes	Subsequent taste testing of BXD RI lines was restricted to these two concentrations (1 and 3 mM for both QHCl and DB).
T1632	607-617	JJ	denotes	Subsequent
T1633	624-631	NN	denotes	testing
T1634	618-623	NN	denotes	taste
T1635	652-662	VBN	denotes	restricted
T1636	632-634	IN	denotes	of
T1637	635-638	NN	denotes	BXD
T1638	642-647	NNS	denotes	lines
T1639	639-641	JJ	denotes	RI
T1640	648-651	VBD	denotes	was
T1641	663-665	IN	denotes	to
T1642	666-671	DT	denotes	these
T1643	676-690	NNS	denotes	concentrations
T1644	672-675	CD	denotes	two
T1645	691-692	-LRB-	denotes	(
T1646	700-702	NN	denotes	mM
T1647	692-693	CD	denotes	1
T1648	694-697	CC	denotes	and
T1649	698-699	CD	denotes	3
T1650	703-706	IN	denotes	for
T1651	707-711	CC	denotes	both
T1652	712-716	NN	denotes	QHCl
T1653	717-720	CC	denotes	and
T1654	721-723	NN	denotes	DB
T1655	723-724	-RRB-	denotes	)
T1656	724-725	.	denotes	.
T1657	725-899	sentence	denotes	Avoidance by male and female B6 and D2 mice increased (as indicated by the decreased lick ratio) in a concentration-dependent manner for both compounds (Figure 1A; Table 1).
T1658	726-735	NN	denotes	Avoidance
T1659	770-779	VBD	denotes	increased
T1660	736-738	IN	denotes	by
T1661	739-743	JJ	denotes	male
T1662	765-769	NNS	denotes	mice
T1663	744-747	CC	denotes	and
T1664	748-754	JJ	denotes	female
T1665	755-757	NN	denotes	B6
T1666	758-761	CC	denotes	and
T1667	762-764	NN	denotes	D2
T1668	780-781	-LRB-	denotes	(
T1669	781-783	IN	denotes	as
T1670	784-793	VBN	denotes	indicated
T1671	794-796	IN	denotes	by
T1672	797-800	DT	denotes	the
T1673	816-821	NN	denotes	ratio
T1674	801-810	VBN	denotes	decreased
T1675	811-815	NN	denotes	lick
T1676	821-822	-RRB-	denotes	)
T1677	823-825	IN	denotes	in
T1678	826-827	DT	denotes	a
T1679	852-858	NN	denotes	manner
T1680	828-841	NN	denotes	concentration
T1681	842-851	JJ	denotes	dependent
T1682	841-842	HYPH	denotes	-
T1683	859-862	IN	denotes	for
T1684	863-867	DT	denotes	both
T1685	868-877	NNS	denotes	compounds
T1686	878-879	-LRB-	denotes	(
T1687	890-895	NN	denotes	Table
T1688	879-885	NN	denotes	Figure
T1714	971-972	,	denotes	,
T1715	978-982	CD	denotes	24.6
T1716	974-975	-RRB-	denotes	]
T1717	976-977	SYM	denotes	>
T1718	982-983	:	denotes	;
T1719	984-985	NN	denotes	p
T1720	986-987	SYM	denotes	<
T1721	994-995	-RRB-	denotes	)
T1722	995-996	.	denotes	.
T1723	996-1077	sentence	denotes	D2 mice displayed decreased aversion relative to B6 mice at both concentrations.
T1724	997-999	NN	denotes	D2
T1725	1000-1004	NNS	denotes	mice
T1726	1005-1014	VBD	denotes	displayed
T1727	1015-1024	VBN	denotes	decreased
T1728	1025-1033	NN	denotes	aversion
T1729	1034-1042	JJ	denotes	relative
T1730	1043-1045	IN	denotes	to
T1731	1046-1048	NN	denotes	B6
T1732	1049-1053	NNS	denotes	mice
T1733	1054-1056	IN	denotes	at
T1734	1057-1061	DT	denotes	both
T1735	1062-1076	NNS	denotes	concentrations
T1736	1076-1077	.	denotes	.
T1737	1077-1177	sentence	denotes	On the other hand, the strains did not significantly differ in taste sensitivity to DB (Figure 1A).
T1738	1078-1080	IN	denotes	On
T1739	1131-1137	VB	denotes	differ
T1740	1081-1084	DT	denotes	the
T1741	1091-1095	NN	denotes	hand
T1742	1085-1090	JJ	denotes	other
T1743	1095-1097	,	denotes	,
T1744	1097-1100	DT	denotes	the
T1745	1101-1108	NNS	denotes	strains
T1746	1109-1112	VBD	denotes	did
T1747	1113-1116	RB	denotes	not
T1748	1117-1130	RB	denotes	significantly
T1749	1138-1140	IN	denotes	in
T1750	1141-1146	NN	denotes	taste
T1751	1147-1158	NN	denotes	sensitivity
T1752	1159-1161	IN	denotes	to
T1753	1162-1164	NN	denotes	DB
T1754	1165-1166	-LRB-	denotes	(
T1755	1166-1172	NN	denotes	Figure
T1756	1173-1175	CD	denotes	1A
T1757	1175-1176	-RRB-	denotes	)
T1758	1176-1177	.	denotes	.
T1759	1177-1222	sentence	denotes	There were no significant effects of gender.
T1760	1178-1183	EX	denotes	There
T1761	1184-1188	VBD	denotes	were
T1762	1189-1191	DT	denotes	no
T1763	1204-1211	NNS	denotes	effects
T1764	1192-1203	JJ	denotes	significant
T1765	1212-1214	IN	denotes	of
T1766	1215-1221	NN	denotes	gender
T1767	1221-1222	.	denotes	.
T7344	1232-1236	NN	denotes	Mean
T7345	1242-1248	NNS	denotes	ratios
T7346	1237-1241	NN	denotes	lick
T7347	1249-1252	IN	denotes	for
T7348	1253-1255	NN	denotes	B6
T7349	1268-1272	NNS	denotes	mice
T7350	1255-1257	,	denotes	,
T7351	1257-1259	NN	denotes	D2
T7352	1260-1263	CC	denotes	and
T7353	1264-1267	NN	denotes	BXD
T7354	1272-1273	.	denotes	.
T2067	4864-4866	NN	denotes	mM
T1689	886-888	CD	denotes	1A
T1690	888-889	:	denotes	;
T1691	896-897	CD	denotes	1
T1692	897-898	-RRB-	denotes	)
T1693	898-899	.	denotes	.
T1694	899-996	sentence	denotes	There was a significant strain difference for both 1 and 3 mM QHCl (F[1,25] > 24.6; p < 0.0001).
T1695	900-905	EX	denotes	There
T1696	906-909	VBD	denotes	was
T1697	910-911	DT	denotes	a
T1698	931-941	NN	denotes	difference
T1699	912-923	JJ	denotes	significant
T1700	924-930	NN	denotes	strain
T1701	942-945	IN	denotes	for
T1702	946-950	DT	denotes	both
T1703	962-966	NN	denotes	QHCl
T1704	951-952	CD	denotes	1
T1705	959-961	NN	denotes	mM
T1706	953-956	CC	denotes	and
T1707	957-958	CD	denotes	3
T1708	967-968	-LRB-	denotes	(
T1709	988-994	CD	denotes	0.0001
T1710	968-969	NN	denotes	F
T1711	972-974	CD	denotes	25
T1712	969-970	-LRB-	denotes	[
T1713	970-971	CD	denotes	1
T1770	4015-4021	VBD	denotes	tested
T1769	4007-4009	PRP	denotes	We
T1768	1222-4064	sentence	denotes	Table 1 Mean lick ratios for B6, D2 and BXD mice. Strain n Water licks/5s 1 mM DB 3 mM DB 3 mM PR 10 mM PR 1 mM QH 3 mM QH B6 16 29.02 ± 1.4 0.606 0.318 0.311 0.164 0.241 0.144 D2 12 33.91 ± 2.4 0.465 0.286 0.616 0.429 0.758 0.305 BXD1 5 32.48 ± 1.5 0.372 0.202 0.314 0.252 0.746 0.422 BXD2 4 36.50 ± 0.9 1.025 0.605 0.208 0.230 0.320 0.215 BXD5 5 37.23 ± 2.7 0.628 0.354 0.502 0.636 0.836 0.452 BXD6 5 22.43 ± 3.5 0.442 0.132 0.200 0.124 0.130 0.080 BXD11 7 34.48 ± 3.9 0.310 0.223 0.387 0.260 0.479 0.260 BXD13 5 27.74 ± 3.4 0.360 0.290 0.472 0.168 0.692 0.330 BXD14 7 31.09 ± 3.5 0.741 0.304 0.293 0.174 0.206 0.126 BXD15 5 37.36 ± 1.5 0.178 0.120 0.468 0.198 0.362 0.222 BXD20 5 31.26 ± 2.7 0.252 0.200 0.162 0.128 0.150 0.116 BXD21 6 19.77 ± 1.5 0.390 0.262 0.313 0.133 0.192 0.217 BXD24 5 33.03 ± 2.4 0.318 0.148 0.490 0.238 0.518 0.370 BXD27 5 33.46 ± 2.5 0.364 0.434 0.216 0.126 0.146 0.142 BXD29 3 40.19 ± 1.5 0.257 0.187 0.657 0.173 0.633 0.333 BXD31 5 19.45 ± 0.8 0.302 0.238 0.152 0.158 0.218 0.194 BXD32 6 27.22 ± 2.3 0.105 0.107 0.385 0.203 0.405 0.245 BXD33 6 29.03 ± 2.2 0.757 0.387 0.377 0.237 0.342 0.188 BXD34 6 23.01 ± 3.4 0.310 0.217 0.843 0.257 0.693 0.355 The number of individual mice tested for each strain (n) is listed in the second column. Subsequent columns show the mean lick rate to water during testing (± SEM), mean lick ratio for denatonium benzoate (DB), PROP (6-n-propylthiouracil; PR) and quinine hydrochloride (QH) at each of two concentrations (see Methods for details). Figure 1 Lick ratios (mean ± SE) for B6, D2 and BXD strains. (A) Mean lick ratios for B6 (filled circles) and D2 (open circles) mice at two concentrations of QHCl and DB. In all panels, a lower mean lick ratio indicates a greater aversion, and therefore greater taste sensitivity, to the stimulus. For panels B, C, and D, each BXD strain is represented by a different color, and listed in order from least sensitive to most sensitive to 1 mM QHCL. (B) Mean lick ratios for the six BXD strains that are most sensitive to QHCl in this assay. (C) Mean lick ratios for the five BXD strains that are least sensitive to QHCl in this assay. (D) Mean lick ratios for the six BXD strains intermediate in QHCl taste sensitivity to those in (B) and (C). Cutoffs for the three QHCl taster groups were arbitrarily set, as there was a continuity of the phenotype at 1 mM QHCl: sensitive strains exhibited a lick ratio for 1 mM QHCl of ≤ 0.3, intermediate strains from 0.31-0.6, and insensitive strains > 0.6. The absence of two distinct phenotypic classes suggests that sensitivity to QHCL is under polygenic control. We next tested mice from 17 BXD lines in the same manner.
T2109	5357-5358	NN	denotes	n
T2108	5357-5358	sentence	denotes	n
T2107	5356-5357	JJ	denotes	i
T2106	5356-5357	sentence	denotes	i
T2105	5355-5356	NN	denotes	l
T2104	5353-5354	NN	denotes	s
T2103	5352-5353	VBG	denotes	a
T2102	5351-5352	JJ	denotes	w
T2101	5347-5350	NN	denotes	QTL
T2100	5345-5346	CD	denotes	6
T2099	5335-5344	NN	denotes	hromosome
T2098	5334-5335	JJ	denotes	c
T2097	5334-5356	sentence	denotes	chromosome 6 QTL was l
T2096	5331-5333	NN	denotes	he
T2095	5330-5331	NN	denotes	T
T2094	5330-5334	sentence	denotes	The
T2093	4975-4976	sentence	denotes
T2092	4974-4975	.	denotes	.
T2091	4973-4974	-RRB-	denotes	)
T2090	4971-4973	CD	denotes	2B
T2089	4964-4970	NN	denotes	Figure
T2088	4963-4964	-LRB-	denotes	(
T2087	4950-4962	NN	denotes	significance
T2086	4944-4945	HYPH	denotes	-
T2085	4945-4949	JJ	denotes	wide
T2084	4938-4944	NN	denotes	genome
T2083	4928-4931	RB	denotes	not
T2082	4932-4937	VB	denotes	reach
T2081	4924-4927	VBD	denotes	did
T2080	4920-4923	CC	denotes	but
T2079	4918-4919	-RRB-	denotes	)
T2078	4912-4913	SYM	denotes	>
T2077	4908-4911	NN	denotes	LRS
T2076	4914-4918	CD	denotes	10.9
T2075	4907-4908	-LRB-	denotes	(
T2074	4896-4906	JJ	denotes	suggestive
T2073	4887-4890	NN	denotes	QTL
T2072	4881-4886	DT	denotes	these
T2071	4878-4880	IN	denotes	of
T2070	4873-4877	DT	denotes	both
T2069	4871-4873	,	denotes	,
T2068	4867-4871	NN	denotes	QHCl
T2119	5400-5406	NN	denotes	Figure
T2117	5382-5389	NN	denotes	D6Mit13
T2116	5380-5382	,	denotes	,
T2115	5367-5373	JJ	denotes	single
T2114	5374-5380	NN	denotes	marker
T2113	5365-5366	DT	denotes	a
T2112	5362-5364	IN	denotes	to
T2111	5358-5361	VBN	denotes	ked
T2110	5358-5410	sentence	denotes	ked to a single marker, D6Mit13 (Table 2, Figure 3).
T3154	11048-11059	NN	denotes	variability
T3153	11048-11288	sentence	denotes	variability between orthologous receptors in these two inbred strains suggested that it might be possible to narrow the physical boundaries of the QHCl taste QTL by determining which Tas2r alleles are correlated with QHCl taste sensitivity.
T3152	11045-11047	DT	denotes	he
T3151	11045-11048	sentence	denotes	he
T3150	11044-11045	NNS	denotes	T
T3149	11044-11045	sentence	denotes	T
T3148	10533-10534	sentence	denotes
T3147	10532-10533	.	denotes	.
T3146	10531-10532	-RRB-	denotes	)
T3145	10522-10525	RB	denotes	not
R4955	T6597	T6598	det	A,QTL
R4956	T6599	T6598	amod	major,QTL
R4957	T6600	T6598	prep	for,QTL
R4958	T6601	T6602	compound	QHCl,taste
R4959	T6602	T6600	pobj	taste,for
R4960	T6603	T6598	prep	on,QTL
R4961	T6604	T6605	compound	mouse,chromosome
R4962	T6605	T6603	pobj	chromosome,on
R4963	T6606	T6605	nummod	6,chromosome
R4964	T6607	T6598	punct	.,QTL
R4965	T6609	T6610	punct	(,panel
R4966	T6610	T6612	parataxis	panel,shows
R4967	T6611	T6610	amod	Top,panel
R4968	T6613	T6610	punct	),panel
R4969	T6614	T6615	det	The,map
R4970	T6615	T6612	nsubj	map,shows
R4971	T6616	T6615	compound	interval,map
R4972	T6617	T6618	punct	(,see
R4973	T6618	T6615	parataxis	see,map
R4974	T6619	T6618	dobj	Methods,see
R4975	T6620	T6618	punct	),see
R4976	T6621	T6622	det	a,QTL
R4977	T6622	T6612	dobj	QTL,shows
R4978	T6623	T6622	amod	significant,QTL
R4979	T6624	T6622	prep	on,QTL
R4980	T6625	T6624	pobj	chromosome,on
R4981	T6626	T6625	nummod	6,chromosome
R4982	T6627	T6628	punct	(,green
R4983	T6628	T6625	parataxis	green,chromosome
R4984	T6629	T6628	punct	),green
R4985	T6630	T6622	cc	and,QTL
R4986	T6631	T6632	det	a,QTL
R4987	T6632	T6622	conj	QTL,QTL
R4988	T6633	T6632	amod	suggestive,QTL
R4989	T6634	T6632	prep	on,QTL
R4990	T6635	T6634	pobj	chromosome,on
R4991	T6636	T6635	nummod	8,chromosome
R4992	T6637	T6638	punct	(,yellow
R4993	T6638	T6635	parataxis	yellow,chromosome
R4994	T6639	T6638	punct	),yellow
R4995	T6640	T6622	acl	affecting,QTL
R4996	T6641	T6642	compound	taste,responses
R4997	T6642	T6640	dobj	responses,affecting
R4998	T6643	T6642	prep	to,responses
R4999	T6644	T6645	nummod	1,mM
R5000	T6645	T6646	compound	mM,QHCl
R5001	T6646	T6643	pobj	QHCl,to
R5002	T6647	T6612	punct	.,shows
R5003	T6649	T6650	punct	(,panel
R5004	T6650	T6652	parataxis	panel,were
R5005	T6651	T6650	amod	Bottom,panel
R5006	T6653	T6650	punct	),panel
R5007	T6654	T6652	prep	For,were
R5008	T6655	T6656	nummod	3,mM
R5009	T6656	T6657	compound	mM,QHCl
R5010	T6657	T6654	pobj	QHCl,For
R5011	T6658	T6652	punct	", ",were
R5012	T6659	T6660	det	both,QTL
R5013	T6660	T6652	nsubj	QTL,were
R5014	T6661	T6652	acomp	suggestive,were
R5015	T6662	T6663	punct	(,yellow
R5016	T6663	T6661	parataxis	yellow,suggestive
R5017	T6664	T6663	punct	),yellow
R5018	T6665	T6652	punct	.,were
R5019	T6667	T6668	det	The,line
R5020	T6668	T6670	nsubj	line,indicates
R5021	T6669	T6668	amod	dashed,line
R5022	T6671	T6672	npadvmod	genome,wide
R5023	T6672	T6674	amod	wide,significance
R5024	T6673	T6672	punct	-,wide
R5025	T6674	T6670	dobj	significance,indicates
R5026	T6675	T6670	punct	.,indicates
R5027	T6700	T6701	det	The,QTL
R5028	T6701	T6703	nsubjpass	QTL,linked
R5029	T6702	T6701	compound	QHCl,QTL
R5030	T6704	T6703	auxpass	is,linked
R5031	T6705	T6703	prep	to,linked
R5032	T6706	T6707	det	a,marker
R5033	T6707	T6705	pobj	marker,to
R5034	T6708	T6707	amod	single,marker
R5035	T6709	T6707	prep	on,marker
R5036	T6710	T6709	pobj	chromosome,on
R5037	T6711	T6710	nummod	6,chromosome
R5038	T6712	T6703	punct	.,linked
R5039	T6714	T6715	punct	(,A
R5040	T6715	T6716	meta	A,correlates
R5041	T6717	T6715	punct	),A
R5042	T6718	T6719	mark	As,shown
R5043	T6719	T6716	advcl	shown,correlates
R5044	T6720	T6719	prep	in,shown
R5045	T6721	T6722	det	the,map
R5046	T6722	T6720	pobj	map,in
R5047	T6723	T6722	amod	interval,map
R5048	T6724	T6722	prep	for,map
R5049	T6725	T6724	pobj	chromosome,for
R5050	T6726	T6725	nummod	6,chromosome
R5051	T6727	T6716	punct	", ",correlates
R5052	T6728	T6729	det	the,value
R5053	T6729	T6716	nsubj	value,correlates
R5054	T6730	T6729	compound	trait,value
R5055	T6731	T6729	punct	(,value
R5056	T6732	T6733	compound	lick,ratio
R5057	T6733	T6729	appos	ratio,value
R5058	T6734	T6733	prep	for,ratio
R5059	T6735	T6736	nummod	1,mM
R5060	T6736	T6737	compound	mM,QHCl
R5061	T6737	T6734	pobj	QHCl,for
R5062	T6738	T6716	punct	),correlates
R5063	T6739	T6716	advmod	strongly,correlates
R5064	T6740	T6716	prep	across,correlates
R5065	T6741	T6742	nmod	BXD,strains
R5066	T6742	T6740	pobj	strains,across
R5067	T6743	T6742	amod	RI,strains
R5068	T6744	T6716	prep	with,correlates
R5069	T6745	T6746	det	the,marker
R5070	T6746	T6744	pobj	marker,with
R5071	T6747	T6746	amod	polymorphic,marker
R5072	T6748	T6746	appos	D6Mit13,marker
R5073	T6749	T6750	punct	(,bold
R5074	T6750	T6746	parataxis	bold,marker
R5075	T6751	T6750	punct	),bold
R5076	T6752	T6716	punct	.,correlates
R5077	T6754	T6755	det	The,line
R5078	T6755	T6757	nsubj	line,indicates
R5079	T6756	T6755	amod	dashed,line
R5080	T6758	T6759	npadvmod	genome,wide
R5081	T6759	T6761	amod	wide,significance
R5082	T6760	T6759	punct	-,wide
R5083	T6761	T6757	dobj	significance,indicates
R5084	T6762	T6757	punct	.,indicates
R5085	T6764	T6765	punct	(,B
R5086	T6765	T6766	meta	B,contains
R5087	T6767	T6765	punct	),B
R5088	T6768	T6769	det	The,QTL
R5089	T6769	T6766	nsubj	QTL,contains
R5090	T6770	T6769	compound	QHCl,QTL
R5091	T6771	T6769	punct	(,QTL
R5092	T6772	T6773	dep	which,lies
R5093	T6773	T6769	relcl	lies,QTL
R5094	T6774	T6773	prep	between,lies
R5095	T6775	T6776	amod	unlinked,markers
R5096	T6776	T6774	pobj	markers,between
R5097	T6777	T6776	appos	D6Mit61,markers
R5098	T6778	T6777	cc	and,D6Mit61
R5099	T6779	T6777	conj	D6Mit,D6Mit61
R5100	T6780	T6779	nummod	374,D6Mit
R5101	T6781	T6769	punct	),QTL
R5102	T6782	T6783	det	a,cluster
R5103	T6783	T6766	dobj	cluster,contains
R5104	T6784	T6783	prep	of,cluster
R5105	T6785	T6786	amod	putative,genes
R5106	T6786	T6784	pobj	genes,of
R5107	T6787	T6788	amod	bitter,taste
R5108	T6788	T6786	compound	taste,genes
R5109	T6789	T6786	compound	receptor,genes
R5110	T6790	T6783	punct	", ",cluster
R5111	T6791	T6792	det	the,Tas2rs
R5112	T6792	T6783	appos	Tas2rs,cluster
R5113	T6793	T6794	punct	(,box
R5114	T6794	T6783	parataxis	box,cluster
R5115	T6795	T6794	amod	gray,box
R5116	T6796	T6794	punct	),box
R5117	T6797	T6766	punct	.,contains
R5118	T6799	T6800	amod	Physical,positions
R5119	T6800	T6801	nsubjpass	positions,given
R5120	T6802	T6800	prep	of,positions
R5121	T6803	T6804	det	the,markers
R5122	T6804	T6802	pobj	markers,of
R5123	T6805	T6804	amod	polymorphic,markers
R5124	T6806	T6801	auxpass	are,given
R5125	T6807	T6801	prep	in,given
R5126	T6808	T6807	pobj	Mb,in
R5127	T6809	T6801	punct	", ",given
R5128	T6810	T6801	cc	and,given
R5129	T6811	T6812	auxpass	are,based
R5130	T6812	T6801	conj	based,given
R5131	T6813	T6812	prep	on,based
R5132	T6814	T6815	det	the,build
R5133	T6815	T6813	pobj	build,on
R5134	T6816	T6815	nmod	May,build
R5135	T6817	T6816	punct	", ",May
R5136	T6818	T6816	npadvmod	2004,May
R5137	T6819	T6815	prep	of,build
R5138	T6820	T6821	det	the,genome
R5139	T6821	T6819	pobj	genome,of
R5140	T6822	T6821	compound	B6,genome
R5141	T6823	T6821	compound	mouse,genome
R5142	T6824	T6801	punct	.,given
R5143	T6826	T6827	det	The,position
R5144	T6827	T6829	nsubj	position,is
R5145	T6828	T6827	amod	physical,position
R5146	T6830	T6827	prep	of,position
R5147	T6831	T6830	pobj	D6Mit194,of
R5148	T6832	T6833	punct	(,*
R5149	T6833	T6827	punct	*,position
R5150	T6834	T6833	punct	),*
R5151	T6835	T6829	acomp	tentative,is
R5152	T6836	T6829	punct	.,is
R5154	T6866	T6867	det	A,map
R5155	T6868	T6867	prep	of,map
R5156	T6869	T6870	det	the,cluster
R5157	T6870	T6868	pobj	cluster,of
R5158	T6871	T6870	amod	distal,cluster
R5159	T6872	T6870	nmod	chromosome,cluster
R5160	T6873	T6872	nummod	6,chromosome
R5161	T6874	T6870	compound	Tas2r,cluster
R5162	T6875	T6867	punct	.,map
R5163	T6877	T6878	compound	Twenty,four
R5164	T6878	T6880	nummod	four,genes
R5165	T6879	T6878	punct	-,four
R5166	T6880	T6883	nsubj	genes,map
R5167	T6881	T6880	amod	intact,genes
R5168	T6882	T6880	compound	Tas2r,genes
R5169	T6884	T6883	prep	to,map
R5170	T6885	T6886	amod	distal,chromosome
R5171	T6886	T6884	pobj	chromosome,to
R5172	T6887	T6886	nummod	6,chromosome
R5173	T6888	T6889	punct	(,black
R5174	T6889	T6886	parataxis	black,chromosome
R5175	T6890	T6889	punct	),black
R5176	T6891	T6883	punct	.,map
R5177	T6893	T6894	det	The,Tas2rs
R5178	T6894	T6895	nsubjpass	Tas2rs,found
R5179	T6896	T6895	auxpass	are,found
R5180	T6897	T6895	prep	in,found
R5181	T6898	T6899	nummod	two,subclusters
R5182	T6899	T6897	pobj	subclusters,in
R5183	T6900	T6899	prep	on,subclusters
R5184	T6901	T6902	det	either,side
R5185	T6902	T6900	pobj	side,on
R5186	T6903	T6902	prep	of,side
R5187	T6904	T6905	det	the,D6Mit13
R5188	T6905	T6903	pobj	D6Mit13,of
R5189	T6906	T6905	amod	polymorphic,D6Mit13
R5190	T6907	T6905	compound	marker,D6Mit13
R5191	T6908	T6909	punct	(,red
R5192	T6909	T6905	parataxis	red,D6Mit13
R5193	T6910	T6909	punct	),red
R5194	T6911	T6899	cc	and,subclusters
R5195	T6912	T6913	nummod	two,genes
R5196	T6913	T6899	conj	genes,subclusters
R5197	T6914	T6913	acl	encoding,genes
R5198	T6915	T6916	npadvmod	proline,rich
R5199	T6916	T6918	amod	rich,proteins
R5200	T6917	T6916	punct	-,rich
R5201	T6918	T6914	dobj	proteins,encoding
R5202	T6919	T6918	amod	salivary,proteins
R5203	T6920	T6918	punct	(,proteins
R5204	T6921	T6918	appos	Prp2,proteins
R5205	T6922	T6921	cc	and,Prp2
R5206	T6923	T6921	conj	Prh1,Prp2
R5207	T6924	T6925	punct	;,red
R5208	T6925	T6918	parataxis	red,proteins
R5209	T6926	T6925	punct	),red
R5210	T6927	T6895	punct	.,found
R5211	T6929	T6930	compound	Map,positions
R5212	T6930	T6931	nsubj	positions,represent
R5213	T6932	T6930	punct	", ",positions
R5214	T6933	T6930	prep	in,positions
R5215	T6934	T6933	pobj	Mb,in
R5216	T6935	T6931	punct	", ",represent
R5217	T6936	T6937	nmod	chromosome,positions
R5218	T6937	T6931	dobj	positions,represent
R5219	T6938	T6936	nummod	6,chromosome
R5220	T6939	T6937	prep	in,positions
R5221	T6940	T6941	det	the,assembly
R5222	T6941	T6939	pobj	assembly,in
R5223	T6942	T6941	nmod	May,assembly
R5224	T6943	T6942	punct	", ",May
R5225	T6944	T6942	npadvmod	2004,May
R5226	T6945	T6941	prep	of,assembly
R5227	T6946	T6947	det	the,genome
R5228	T6947	T6945	pobj	genome,of
R5229	T6948	T6947	compound	B6,genome
R5230	T6949	T6931	punct	.,represent
R5231	T6978	T6979	amod	Allelic,variation
R5232	T6980	T6979	prep	across,variation
R5233	T6981	T6980	pobj	strains,across
R5234	T6982	T6979	prep	for,variation
R5235	T6983	T6984	nummod	four,Tas2rs
R5236	T6984	T6982	pobj	Tas2rs,for
R5237	T6985	T6979	punct	.,variation
R5238	T6987	T6988	nmod	B6,alleles
R5239	T6988	T6991	nsubjpass	alleles,differentiated
R5240	T6989	T6987	cc	and,B6
R5241	T6990	T6987	conj	D2,B6
R5242	T6992	T6988	prep	of,alleles
R5243	T6993	T6994	nummod	four,Tas2rs
R5244	T6994	T6992	pobj	Tas2rs,of
R5245	T6995	T6991	aux	can,differentiated
R5246	T6996	T6991	auxpass	be,differentiated
R5247	T6997	T6991	prep	based,differentiated
R5248	T6998	T6997	prep	on,based
R5249	T6999	T7000	amod	diagnostic,digests
R5250	T7000	T6998	pobj	digests,on
R5251	T7001	T7000	compound	restriction,digests
R5252	T7002	T7000	prep	of,digests
R5253	T7003	T7004	amod	amplified,products
R5254	T7004	T7002	pobj	products,of
R5255	T7005	T7004	compound	PCR,products
R5256	T7006	T7004	punct	(,products
R5257	T7007	T7004	appos	Tas2r105,products
R5258	T7008	T7007	punct	", ",Tas2r105
R5259	T7009	T7007	conj	Tas2r116,Tas2r105
R5260	T7010	T7009	cc	and,Tas2r116
R5261	T7011	T7009	conj	Tas2r131,Tas2r116
R5262	T7012	T6998	punct	),on
R5263	T7013	T6998	cc	or,on
R5264	T7014	T6998	conj	on,on
R5265	T7015	T7016	det	the,presence
R5266	T7016	T7014	pobj	presence,on
R5267	T7017	T7016	cc	or,presence
R5268	T7018	T7016	conj	absence,presence
R5269	T7019	T7016	prep	of,presence
R5270	T7020	T7021	det	a,product
R5271	T7021	T7019	pobj	product,of
R5272	T7022	T7021	compound	PCR,product
R5273	T7023	T7021	punct	(,product
R5274	T7024	T7021	appos	Tas2r120,product
R5275	T7025	T6991	punct	),differentiated
R5276	T7026	T6991	punct	.,differentiated
R5277	T7028	T7029	prep	In,correlated
R5278	T7030	T7028	pobj	each,In
R5279	T7031	T7030	prep	of,each
R5280	T7032	T7033	det	the,strains
R5281	T7033	T7031	pobj	strains,of
R5282	T7034	T7033	nummod	17,strains
R5283	T7035	T7033	compound	BXD,strains
R5284	T7036	T7033	acl	tested,strains
R5285	T7037	T7029	punct	", ",correlated
R5286	T7038	T7039	compound	Tas2r,genotype
R5287	T7039	T7029	nsubjpass	genotype,correlated
R5288	T7040	T7029	auxpass	was,correlated
R5289	T7041	T7029	advmod	always,correlated
R5290	T7042	T7029	prep	with,correlated
R5291	T7043	T7044	compound	QHCl,taster
R5292	T7044	T7045	compound	taster,phenotype
R5293	T7045	T7042	pobj	phenotype,with
R5294	T7046	T7047	punct	(,phenotype
R5295	T7047	T7045	parataxis	phenotype,phenotype
R5296	T7048	T7049	nsubj	blue,phenotype
R5297	T7049	T7047	ccomp	phenotype,phenotype
R5298	T7050	T7049	punct	=,phenotype
R5299	T7051	T7052	compound	B6,taster
R5300	T7052	T7049	compound	taster,phenotype
R5301	T7053	T7047	punct	", ",phenotype
R5302	T7054	T7047	nsubj	red,phenotype
R5303	T7055	T7047	punct	=,phenotype
R5304	T7056	T7057	compound	D2,taster
R5305	T7057	T7047	compound	taster,phenotype
R5306	T7058	T7047	punct	),phenotype
R5307	T7059	T7029	punct	.,correlated
R5308	T7062	T7063	amod	additional,file
R5309	T7063	T7061	dobj	file,See
R5310	T7064	T7063	nummod	1,file
R5311	T7065	T7063	punct	: ,file
R5312	T7066	T7063	npadvmod	Table,file
R5313	T7067	T7066	nummod	3,Table
R5314	T7068	T7061	prep	for,See
R5315	T7069	T7070	compound	restriction,enzymes
R5316	T7070	T7068	pobj	enzymes,for
R5317	T7071	T7070	cc	and,enzymes
R5318	T7072	T7070	conj	oligonucleotides,enzymes
R5319	T7073	T7061	punct	.,See
R5320	T7095	T7096	det	The,cluster
R5321	T7096	T7098	nsubj	cluster,is
R5322	T7097	T7096	compound	Tas2r,cluster
R5323	T7099	T7100	det	a,haplotype
R5324	T7100	T7098	attr	haplotype,is
R5325	T7101	T7100	amod	single,haplotype
R5326	T7102	T7098	prep	in,is
R5327	T7103	T7104	nmod	BXD,Ty
R5328	T7104	T7106	nmod	Ty,mice
R5329	T7105	T7104	punct	/,Ty
R5330	T7106	T7102	pobj	mice,in
R5331	T7107	T7106	amod	RI,mice
R5332	T7108	T7098	punct	.,is
R5333	T7110	T7111	det	The,exon
R5334	T7111	T7113	nsubj	exon,was
R5335	T7112	T7111	amod	coding,exon
R5336	T7114	T7111	prep	of,exon
R5337	T7115	T7114	pobj	each,of
R5338	T7116	T7115	prep	of,each
R5339	T7117	T7118	nummod	21,Tas2rs
R5340	T7118	T7116	pobj	Tas2rs,of
R5341	T7119	T7118	prep	in,Tas2rs
R5342	T7120	T7121	det	the,cluster
R5343	T7121	T7119	pobj	cluster,in
R5344	T7122	T7121	amod	distal,cluster
R5345	T7123	T7121	nmod	chromosome,cluster
R5346	T7124	T7123	nummod	6,chromosome
R5347	T7125	T7126	amod	amplified,DNA
R5348	T7126	T7113	attr	DNA,was
R5349	T7127	T7126	amod	genomic,DNA
R5350	T7128	T7126	prep	from,DNA
R5351	T7129	T7130	nummod	29,strains
R5352	T7130	T7128	pobj	strains,from
R5353	T7131	T7132	nmod	BXD,Ty
R5354	T7132	T7130	nmod	Ty,strains
R5355	T7133	T7132	punct	/,Ty
R5356	T7134	T7130	amod	RI,strains
R5357	T7135	T7113	punct	.,was
R5358	T7137	T7138	det	Each,Tas2r
R5359	T7138	T7139	nsubj	Tas2r,originated
R5360	T7140	T7138	prep	within,Tas2r
R5361	T7141	T7142	det	an,strain
R5362	T7142	T7140	pobj	strain,within
R5363	T7143	T7142	amod	individual,strain
R5364	T7144	T7142	compound	BXD,strain
R5365	T7145	T7139	prep	from,originated
R5366	T7146	T7147	det	the,strain
R5367	T7147	T7145	pobj	strain,from
R5368	T7148	T7147	amod	same,strain
R5369	T7149	T7147	amod	parental,strain
R5370	T7150	T7151	punct	(,white
R5371	T7151	T7139	parataxis	white,originated
R5372	T7152	T7153	compound	B6,allele
R5373	T7153	T7154	nsubj	allele,gray
R5374	T7154	T7151	ccomp	gray,white
R5375	T7155	T7154	punct	=,gray
R5376	T7156	T7151	punct	", ",white
R5377	T7157	T7158	compound	D2,allele
R5378	T7158	T7151	nsubj	allele,white
R5379	T7159	T7151	punct	=,white
R5380	T7160	T7151	punct	),white
R5381	T7161	T7139	punct	.,originated
R5382	T7163	T7164	det	The,strains
R5383	T7164	T7167	nsubjpass	strains,indicated
R5384	T7165	T7164	nummod	17,strains
R5385	T7166	T7164	compound	BXD,strains
R5386	T7168	T7169	dep	that,tested
R5387	T7169	T7164	relcl	tested,strains
R5388	T7170	T7169	auxpass	were,tested
R5389	T7171	T7169	advmod	behaviorally,tested
R5390	T7172	T7169	prep	in,tested
R5391	T7173	T7174	det	this,study
R5392	T7174	T7172	pobj	study,in
R5393	T7175	T7167	auxpass	are,indicated
R5394	T7176	T7177	punct	(,*
R5395	T7177	T7167	punct	*,indicated
R5396	T7178	T7177	punct	),*
R5397	T7179	T7167	punct	.,indicated
R5398	T7207	T7208	compound	Tas2r,genotype
R5399	T7208	T7209	nsubj	genotype,correlates
R5400	T7210	T7209	prep	with,correlates
R5401	T7211	T7212	compound	QHCl,taste
R5402	T7212	T7213	compound	taste,phenotype
R5403	T7213	T7210	pobj	phenotype,with
R5404	T7214	T7209	punct	.,correlates
R5405	T7216	T7217	compound	Mean,ratios
R5406	T7217	T7219	nsubjpass	ratios,grouped
R5407	T7218	T7217	compound	lick,ratios
R5408	T7220	T7217	prep	of,ratios
R5409	T7221	T7222	nmod	B6,strains
R5410	T7222	T7220	pobj	strains,of
R5411	T7223	T7221	punct	", ",B6
R5412	T7224	T7221	conj	D2,B6
R5413	T7225	T7224	cc	and,D2
R5414	T7226	T7224	conj	BXD,D2
R5415	T7227	T7222	acl	reported,strains
R5416	T7228	T7227	prep	in,reported
R5417	T7229	T7228	pobj	Figure,in
R5418	T7230	T7229	nummod	1,Figure
R5419	T7231	T7219	auxpass	are,grouped
R5420	T7232	T7219	prep	based,grouped
R5421	T7233	T7232	prep	on,based
R5422	T7234	T7235	compound	Tas2r,haplotype
R5423	T7235	T7233	pobj	haplotype,on
R5424	T7236	T7237	punct	(,red
R5425	T7237	T7219	parataxis	red,grouped
R5426	T7238	T7239	compound	B6,haplotype
R5427	T7239	T7240	nsubj	haplotype,blue
R5428	T7240	T7237	ccomp	blue,red
R5429	T7241	T7240	punct	=,blue
R5430	T7242	T7237	punct	", ",red
R5431	T7243	T7244	compound	D2,haplotype
R5432	T7244	T7237	nsubj	haplotype,red
R5433	T7245	T7237	punct	=,red
R5434	T7246	T7237	punct	),red
R5435	T7247	T7219	punct	.,grouped
R5436	T7249	T7250	compound	B6,mice
R5437	T7250	T7251	nsubj	mice,are
R5438	T7252	T7253	punct	(,line
R5439	T7253	T7250	parataxis	line,mice
R5440	T7254	T7253	amod	blue,line
R5441	T7255	T7253	prep	on,line
R5442	T7256	T7257	amod	left,panel
R5443	T7257	T7255	pobj	panel,on
R5444	T7258	T7253	punct	),line
R5445	T7259	T7260	advmod	more,sensitive
R5446	T7260	T7251	acomp	sensitive,are
R5447	T7261	T7260	prep	to,sensitive
R5448	T7262	T7263	nummod	1,mM
R5449	T7263	T7264	nmod	mM,QHCl
R5450	T7264	T7261	pobj	QHCl,to
R5451	T7265	T7263	cc	and,mM
R5452	T7266	T7267	nummod	3,mM
R5453	T7267	T7263	conj	mM,mM
R5454	T7268	T7269	mark	than,are
R5455	T7269	T7260	advcl	are,sensitive
R5456	T7270	T7271	compound	D2,mice
R5457	T7271	T7269	nsubj	mice,are
R5458	T7272	T7273	punct	(,line
R5459	T7273	T7271	parataxis	line,mice
R5460	T7274	T7273	amod	red,line
R5461	T7275	T7273	prep	on,line
R5462	T7276	T7277	amod	left,panel
R5463	T7277	T7275	pobj	panel,on
R5464	T7278	T7273	punct	),line
R5465	T7279	T7269	prep	in,are
R5466	T7280	T7281	amod	brief,access
R5467	T7281	T7282	compound	access,tests
R5468	T7282	T7279	pobj	tests,in
R5469	T7283	T7282	compound	taste,tests
R5470	T7284	T7251	punct	.,are
R5471	T7286	T7287	advmod	Similarly,are
R5472	T7288	T7287	punct	", ",are
R5473	T7289	T7290	compound	BXD,strains
R5474	T7290	T7287	nsubj	strains,are
R5475	T7291	T7290	prep	with,strains
R5476	T7292	T7293	det	the,haplotype
R5477	T7293	T7291	pobj	haplotype,with
R5478	T7294	T7295	compound	B6,Tas2r
R5479	T7295	T7293	compound	Tas2r,haplotype
R5480	T7296	T7297	punct	(,panel
R5481	T7297	T7293	parataxis	panel,haplotype
R5482	T7298	T7299	amod	blue,lines
R5483	T7299	T7297	dep	lines,panel
R5484	T7300	T7297	punct	", ",panel
R5485	T7301	T7297	amod	right,panel
R5486	T7302	T7297	punct	),panel
R5487	T7303	T7304	advmod	more,sensitive
R5488	T7304	T7287	acomp	sensitive,are
R5489	T7305	T7304	prep	to,sensitive
R5490	T7306	T7305	pobj	QHCl,to
R5491	T7307	T7308	mark	than,are
R5492	T7308	T7304	advcl	are,sensitive
R5493	T7309	T7310	compound	BXD,strains
R5494	T7310	T7308	nsubj	strains,are
R5495	T7311	T7310	prep	with,strains
R5496	T7312	T7313	det	the,haplotype
R5497	T7313	T7311	pobj	haplotype,with
R5498	T7314	T7315	compound	D2,Tas2r
R5499	T7315	T7313	compound	Tas2r,haplotype
R5500	T7316	T7317	punct	(,panel
R5501	T7317	T7308	parataxis	panel,are
R5502	T7318	T7319	amod	red,lines
R5503	T7319	T7317	dep	lines,panel
R5504	T7320	T7317	punct	", ",panel
R5505	T7321	T7317	amod	right,panel
R5506	T7322	T7317	punct	),panel
R5507	T7323	T7287	punct	.,are
R5508	T7325	T7326	det	The,strains
R5509	T7326	T7328	nsubjpass	strains,listed
R5510	T7327	T7326	compound	BXD,strains
R5511	T7329	T7328	auxpass	are,listed
R5512	T7330	T7328	prep	in,listed
R5513	T7331	T7330	pobj	order,in
R5514	T7332	T7328	prep	from,listed
R5515	T7333	T7332	amod	least,from
R5516	T7334	T7332	prep	to,from
R5517	T7335	T7334	amod	most,to
R5518	T7336	T7332	amod	sensitive,from
R5519	T7337	T7336	prep	to,sensitive
R5520	T7338	T7339	nummod	1,mM
R5521	T7339	T7340	compound	mM,QHCL
R5522	T7340	T7337	pobj	QHCL,to
R5523	T7341	T7328	punct	.,listed
R5524	T7344	T7345	compound	Mean,ratios
R5525	T7346	T7345	compound	lick,ratios
R5526	T7347	T7345	prep	for,ratios
R5527	T7348	T7349	nmod	B6,mice
R5528	T7349	T7347	pobj	mice,for
R5529	T7350	T7348	punct	", ",B6
R5530	T7351	T7348	conj	D2,B6
R5531	T7352	T7351	cc	and,D2
R5532	T7353	T7351	conj	BXD,D2
R5533	T7354	T7345	punct	.,ratios
R1075	T1522	T1523	compound	Taste,testing
R1076	T1525	T1526	amod	Previous,efforts
R1077	T1526	T1527	nsubj	efforts,utilized
R1078	T1528	T1529	aux	to,map
R1079	T1529	T1526	acl	map,efforts
R1080	T1530	T1529	dobj	QTL,map
R1081	T1531	T1530	prep	for,QTL
R1082	T1532	T1533	amod	bitter,taste
R1083	T1533	T1531	pobj	taste,for
R1084	T1534	T1527	aux	have,utilized
R1085	T1535	T1536	compound	consumption,tests
R1086	T1536	T1527	dobj	tests,utilized
R1087	T1537	T1538	dep	that,confounded
R1088	T1538	T1536	relcl	confounded,tests
R1089	T1539	T1538	aux	may,confounded
R1090	T1540	T1538	auxpass	be,confounded
R1091	T1541	T1538	agent	by,confounded
R1092	T1542	T1543	det	the,contributions
R1093	T1543	T1541	pobj	contributions,by
R1094	T1544	T1543	prep	of,contributions
R1095	T1545	T1546	amod	post-ingestive,effects
R1096	T1546	T1544	pobj	effects,of
R1097	T1547	T1548	punct	[,29
R1098	T1548	T1538	parataxis	29,confounded
R1099	T1549	T1548	punct	],29
R1100	T1550	T1527	punct	.,utilized
R1101	T1552	T1553	nsubj	We,used
R1102	T1554	T1555	det	a,test
R1103	T1555	T1553	dobj	test,used
R1104	T1556	T1555	amod	modified,test
R1105	T1557	T1558	amod	brief,access
R1106	T1558	T1555	compound	access,test
R1107	T1559	T1558	punct	-,access
R1108	T1560	T1555	compound	lick,test
R1109	T1561	T1555	punct	", ",test
R1110	T1562	T1563	dep	which,minimizes
R1111	T1563	T1555	relcl	minimizes,test
R1112	T1564	T1565	det	the,contribution
R1113	T1565	T1563	dobj	contribution,minimizes
R1114	T1566	T1565	prep	of,contribution
R1115	T1567	T1568	amod	such,effects
R1116	T1568	T1566	pobj	effects,of
R1117	T1569	T1570	punct	[,37
R1118	T1570	T1563	parataxis	37,minimizes
R1119	T1571	T1570	nummod	29,37
R1120	T1572	T1570	punct	",",37
R1121	T1573	T1570	punct	],37
R1122	T1574	T1575	aux	to,determine
R1123	T1575	T1553	advcl	determine,used
R1124	T1576	T1577	mark	whether,display
R1125	T1577	T1575	ccomp	display,determine
R1126	T1578	T1579	nmod	B6,mice
R1127	T1579	T1577	nsubj	mice,display
R1128	T1580	T1578	cc	and,B6
R1129	T1581	T1578	conj	D2,B6
R1130	T1582	T1577	dobj	differences,display
R1131	T1583	T1582	prep	in,differences
R1132	T1584	T1585	compound	taste,sensitivity
R1133	T1585	T1583	pobj	sensitivity,in
R1134	T1586	T1585	prep	to,sensitivity
R1135	T1587	T1588	det	the,stimuli
R1136	T1588	T1586	pobj	stimuli,to
R1137	T1589	T1588	compound	taste,stimuli
R1138	T1590	T1588	appos	QHCl,stimuli
R1139	T1591	T1590	cc	and,QHCl
R1140	T1592	T1590	conj	DB,QHCl
R1141	T1593	T1553	punct	.,used
R1142	T1595	T1596	prep	After,selected
R1143	T1597	T1598	advmod	initially,screening
R1144	T1598	T1595	pcomp	screening,After
R1145	T1599	T1600	nmod	B6,mice
R1146	T1600	T1598	dobj	mice,screening
R1147	T1601	T1599	cc	and,B6
R1148	T1602	T1599	conj	D2,B6
R1149	T1603	T1604	aux	to,determine
R1150	T1604	T1598	advcl	determine,screening
R1151	T1605	T1606	compound	stimulus,concentrations
R1152	T1606	T1604	dobj	concentrations,determine
R1153	T1607	T1608	dep	that,were
R1154	T1608	T1606	relcl	were,concentrations
R1155	T1609	T1608	acomp	aversive,were
R1156	T1610	T1609	cc	but,aversive
R1157	T1611	T1610	neg	not,but
R1158	T1612	T1609	conj	saturating,aversive
R1159	T1613	T1614	punct	[,47
R1160	T1614	T1604	parataxis	47,determine
R1161	T1615	T1614	punct	],47
R1162	T1616	T1596	punct	", ",selected
R1163	T1617	T1596	nsubj	we,selected
R1164	T1618	T1619	nummod	two,concentrations
R1165	T1619	T1596	dobj	concentrations,selected
R1166	T1620	T1619	compound	ligand,concentrations
R1167	T1621	T1619	prep	for,concentrations
R1168	T1622	T1623	det	each,compound
R1169	T1623	T1621	pobj	compound,for
R1170	T1624	T1625	dep	that,differentiated
R1171	T1625	T1619	relcl	differentiated,concentrations
R1172	T1626	T1625	advmod	best,differentiated
R1173	T1627	T1628	det	the,strains
R1174	T1628	T1625	dobj	strains,differentiated
R1175	T1629	T1628	nummod	two,strains
R1176	T1630	T1596	punct	.,selected
R1177	T1632	T1633	amod	Subsequent,testing
R1178	T1633	T1635	nsubjpass	testing,restricted
R1179	T1634	T1633	compound	taste,testing
R1180	T1636	T1633	prep	of,testing
R1181	T1637	T1638	nmod	BXD,lines
R1182	T1638	T1636	pobj	lines,of
R1183	T1639	T1638	amod	RI,lines
R1184	T1640	T1635	auxpass	was,restricted
R1185	T1641	T1635	prep	to,restricted
R1186	T1642	T1643	det	these,concentrations
R1187	T1643	T1641	pobj	concentrations,to
R1188	T1644	T1643	nummod	two,concentrations
R1189	T1645	T1646	punct	(,mM
R1190	T1646	T1635	parataxis	mM,restricted
R1191	T1647	T1646	nummod	1,mM
R1192	T1648	T1647	cc	and,1
R1193	T1649	T1647	conj	3,1
R1194	T1650	T1646	prep	for,mM
R1195	T1651	T1652	preconj	both,QHCl
R1196	T1652	T1650	pobj	QHCl,for
R1197	T1653	T1652	cc	and,QHCl
R1198	T1654	T1652	conj	DB,QHCl
R1199	T1655	T1646	punct	),mM
R1200	T1656	T1635	punct	.,restricted
R1201	T1658	T1659	nsubj	Avoidance,increased
R1202	T1660	T1658	prep	by,Avoidance
R1203	T1661	T1662	amod	male,mice
R1204	T1662	T1660	pobj	mice,by
R1205	T1663	T1661	cc	and,male
R1206	T1664	T1661	conj	female,male
R1207	T1665	T1662	nmod	B6,mice
R1208	T1666	T1665	cc	and,B6
R1209	T1667	T1665	conj	D2,B6
R1210	T1668	T1659	punct	(,increased
R1211	T1669	T1670	mark	as,indicated
R1212	T1670	T1659	advcl	indicated,increased
R1213	T1671	T1670	agent	by,indicated
R1214	T1672	T1673	det	the,ratio
R1215	T1673	T1671	pobj	ratio,by
R1216	T1674	T1673	amod	decreased,ratio
R1217	T1675	T1673	compound	lick,ratio
R1218	T1676	T1659	punct	),increased
R1219	T1677	T1659	prep	in,increased
R1220	T1678	T1679	det	a,manner
R1221	T1679	T1677	pobj	manner,in
R1222	T1680	T1681	npadvmod	concentration,dependent
R1223	T1681	T1679	amod	dependent,manner
R1224	T1682	T1681	punct	-,dependent
R1225	T1683	T1679	prep	for,manner
R1226	T1684	T1685	det	both,compounds
R1227	T1685	T1683	pobj	compounds,for
R1228	T1686	T1687	punct	(,Table
R1229	T1687	T1679	parataxis	Table,manner
R1230	T1688	T1687	dep	Figure,Table
R1231	T1689	T1688	nummod	1A,Figure
R1232	T1690	T1687	punct	;,Table
R1233	T1691	T1687	nummod	1,Table
R1234	T1692	T1687	punct	),Table
R1235	T1693	T1659	punct	.,increased
R1236	T1695	T1696	expl	There,was
R1237	T1697	T1698	det	a,difference
R1239	T1699	T1698	amod	significant,difference
R1257	T1717	T1715	punct	>,24.6
R1258	T1718	T1709	punct	;,0.0001
R1259	T1719	T1709	nsubj	p,0.0001
R1260	T1720	T1709	punct	<,0.0001
R1261	T1721	T1709	punct	),0.0001
R1262	T1722	T1696	punct	.,was
R1263	T1724	T1725	compound	D2,mice
R1264	T1725	T1726	nsubj	mice,displayed
R1265	T1727	T1728	amod	decreased,aversion
R1266	T1728	T1726	dobj	aversion,displayed
R1267	T1729	T1728	amod	relative,aversion
R1268	T1730	T1729	prep	to,relative
R1269	T1731	T1732	compound	B6,mice
R1270	T1732	T1730	pobj	mice,to
R1271	T1733	T1726	prep	at,displayed
R1272	T1734	T1735	det	both,concentrations
R1273	T1735	T1733	pobj	concentrations,at
R1274	T1736	T1726	punct	.,displayed
R1275	T1738	T1739	prep	On,differ
R1276	T1740	T1741	det	the,hand
R1277	T1741	T1738	pobj	hand,On
R1278	T1742	T1741	amod	other,hand
R1279	T1743	T1739	punct	", ",differ
R1280	T1744	T1745	det	the,strains
R1281	T1745	T1739	nsubj	strains,differ
R1282	T1746	T1739	aux	did,differ
R1283	T1747	T1739	neg	not,differ
R1284	T1748	T1739	advmod	significantly,differ
R1285	T1749	T1739	prep	in,differ
R1286	T1750	T1751	compound	taste,sensitivity
R1287	T1751	T1749	pobj	sensitivity,in
R1288	T1752	T1751	prep	to,sensitivity
R1289	T1753	T1752	pobj	DB,to
R1290	T1754	T1755	punct	(,Figure
R1291	T1755	T1739	parataxis	Figure,differ
R1292	T1756	T1755	nummod	1A,Figure
R1293	T1757	T1755	punct	),Figure
R1294	T1758	T1739	punct	.,differ
R1295	T1760	T1761	expl	There,were
R1296	T1762	T1763	det	no,effects
R1297	T1763	T1761	attr	effects,were
R1298	T1764	T1763	amod	significant,effects
R1299	T1765	T1763	prep	of,effects
R1300	T1766	T1765	pobj	gender,of
R1301	T1767	T1761	punct	.,were
R1333	T1803	T1796	punct	),Table
R1334	T1804	T1785	punct	.,avoided
R1335	T1806	T1807	advmod	However,vary
R1336	T1807	T1814	ccomp	vary,are
R1337	T1808	T1807	punct	", ",vary
R1338	T1809	T1810	nmod	QHCl,sensitivity
R1339	T1810	T1807	nsubj	sensitivity,vary
R1340	T1811	T1809	cc	and,QHCl
R1341	T1812	T1809	conj	DB,QHCl
R1342	T1813	T1810	compound	taste,sensitivity
R1343	T1815	T1807	advmod	independently,vary
R1344	T1816	T1807	prep	across,vary
R1345	T1817	T1818	det	these,strains
R1346	T1818	T1816	pobj	strains,across
R1347	T1819	T1818	amod	RI,strains
R1348	T1820	T1814	punct	: ,are
R1349	T1821	T1822	det	some,strains
R1350	T1822	T1814	nsubj	strains,are
R1351	T1823	T1824	advmod	highly,sensitive
R1352	T1824	T1822	amod	sensitive,strains
R1353	T1825	T1824	prep	to,sensitive
R1354	T1826	T1825	pobj	QHCl,to
R1355	T1827	T1828	advmod	relatively,insensitive
R1356	T1828	T1814	acomp	insensitive,are
R1357	T1829	T1828	prep	to,insensitive
R1358	T1830	T1829	pobj	DB,to
R1359	T1831	T1828	punct	", ",insensitive
R1360	T1832	T1828	cc	and,insensitive
R1361	T1833	T1834	advmod	vice,versa
R1362	T1834	T1828	conj	versa,insensitive
R1363	T1835	T1836	punct	(,1B
R1364	T1836	T1814	parataxis	1B,are
R1365	T1837	T1836	nmod	Figures,1B
R1366	T1838	T1839	punct	–,1D
R1367	T1839	T1836	prep	1D,1B
R1368	T1840	T1836	punct	),1B
R1369	T1841	T1814	punct	.,are
R1371	T1946	T1947	compound	QTL,mapping
R1372	T1949	T1950	compound	Linkage,analysis
R1373	T1950	T1951	nsubjpass	analysis,conducted
R1374	T1952	T1951	auxpass	was,conducted
R1375	T1953	T1951	advcl	using,conducted
R1376	T1954	T1955	compound	Map,Manager
R1377	T1955	T1956	compound	Manager,QTX
R1378	T1956	T1953	dobj	QTX,using
R1379	T1957	T1958	punct	(,38
R1380	T1958	T1956	parataxis	38,QTX
R1381	T1959	T1958	dep	version,38
R1382	T1960	T1959	nummod	0.30,version
R1383	T1961	T1958	punct	[,38
R1384	T1962	T1958	punct	],38
R1385	T1963	T1958	punct	),38
R1386	T1964	T1951	punct	.,conducted
R1387	T1966	T1967	det	No,QTLs
R1388	T1967	T1969	nsubjpass	QTLs,identified
R1389	T1968	T1967	amod	significant,QTLs
R1390	T1970	T1969	auxpass	were,identified
R1391	T1971	T1969	prep	for,identified
R1392	T1972	T1973	compound	DB,sensitivity
R1393	T1973	T1971	pobj	sensitivity,for
R1394	T1974	T1973	compound	taste,sensitivity
R1395	T1975	T1969	punct	", ",identified
R1396	T1976	T1977	mark	although,were
R1397	T1977	T1969	advcl	were,identified
R1398	T1978	T1979	amod	several,associations
R1399	T1979	T1977	nsubj	associations,were
R1400	T1980	T1979	prep	with,associations
R1401	T1981	T1980	pobj	markers,with
R1402	T1982	T1981	prep	on,markers
R1403	T1983	T1984	nmod	chromosomes,2
R1404	T1984	T1982	pobj	2,on
R1405	T1985	T1984	punct	",",2
R1406	T1986	T1984	conj	8,2
R1407	T1987	T1986	cc	and,8
R1408	T1988	T1986	conj	12,8
R1409	T1989	T1977	punct	"""",were
R1410	T1990	T1977	acomp	suggestive,were
R1411	T1991	T1977	punct	"""",were
R1412	T1992	T1993	punct	(,see
R1413	T1993	T1977	parataxis	see,were
R1414	T1994	T1995	nsubj	LRS,9.4
R1415	T1995	T1993	ccomp	9.4,see
R1416	T1996	T1995	punct	>,9.4
R1417	T1997	T1993	punct	", ",see
R1418	T1998	T1999	npadvmod	genome,wide
R1419	T1999	T2001	amod	wide,p
R1420	T2000	T1999	punct	-,wide
R1421	T2001	T2002	nsubj	p,0.65
R1422	T2002	T1993	ccomp	0.65,see
R1423	T2003	T2002	punct	=,0.65
R1424	T2004	T1993	punct	;,see
R1425	T2005	T2006	amod	Additional,File
R1426	T2006	T1993	dobj	File,see
R1427	T2007	T2006	nummod	1,File
R1428	T2008	T1993	punct	),see
R1429	T2009	T1969	punct	.,identified
R1430	T2011	T2012	det	A,QTL
R1431	T2012	T2026	nsubjpass	QTL,indicated
R1432	T2013	T2012	amod	significant,QTL
R1433	T2014	T2015	punct	(,0.05
R1434	T2015	T2013	parataxis	0.05,significant
R1435	T2016	T2017	nsubj	LRS,20.5
R1436	T2017	T2015	ccomp	20.5,0.05
R1437	T2018	T2017	punct	>,20.5
R1438	T2019	T2015	punct	;,0.05
R1439	T2020	T2021	npadvmod	genome,wide
R1440	T2021	T2023	amod	wide,p
R1441	T2022	T2021	punct	-,wide
R1442	T2023	T2015	nsubj	p,0.05
R1443	T2024	T2015	punct	=,0.05
R1444	T2025	T2015	punct	),0.05
R1445	T2026	T2034	ccomp	indicated,were
R1446	T2027	T2012	prep	for,QTL
R1447	T2028	T2027	pobj	sensitivity,for
R1448	T2029	T2028	prep	to,sensitivity
R1449	T2030	T2031	nummod	1,mM
R1450	T2031	T2032	compound	mM,QHCl
R1451	T2032	T2029	pobj	QHCl,to
R1452	T2033	T2026	auxpass	was,indicated
R1453	T2035	T2026	prep	on,indicated
R1454	T2036	T2035	pobj	chromosome,on
R1455	T2037	T2036	nummod	6,chromosome
R1456	T2038	T2026	punct	", ",indicated
R1457	T2039	T2040	mark	with,QTL
R1458	T2040	T2026	advcl	QTL,indicated
R1459	T2041	T2040	det	a,QTL
R1460	T2042	T2040	amod	second,QTL
R1461	T2043	T2040	punct	", ",QTL
R1462	T2044	T2040	amod	suggestive,QTL
R1463	T2045	T2046	punct	(,0.65
R1464	T2046	T2040	parataxis	0.65,QTL
R1465	T2047	T2048	nsubj	LRS,11.4
R1466	T2048	T2046	ccomp	11.4,0.65
R1467	T2049	T2048	punct	>,11.4
R1468	T2050	T2046	punct	;,0.65
R1469	T2051	T2052	npadvmod	genome,wide
R1470	T2052	T2054	amod	wide,p
R1471	T2053	T2052	punct	-,wide
R1472	T2054	T2046	nsubj	p,0.65
R1473	T2055	T2046	punct	=,0.65
R1474	T2056	T2046	punct	),0.65
R1475	T2057	T2040	prep	on,QTL
R1476	T2058	T2057	pobj	chromosome,on
R1477	T2059	T2058	nummod	8,chromosome
R1478	T2060	T2061	punct	(,Figure
R1479	T2061	T2058	parataxis	Figure,chromosome
R1480	T2062	T2061	nummod	2A,Figure
R1481	T2063	T2061	punct	),Figure
R1482	T2064	T2034	punct	;,were
R1483	T2065	T2034	prep	at,were
R1484	T2066	T2067	nummod	3,mM
R1485	T2067	T2068	compound	mM,QHCl
R1486	T2068	T2065	pobj	QHCl,at
R1487	T2069	T2034	punct	", ",were
R1488	T2070	T2034	nsubj	both,were
R1489	T2071	T2070	prep	of,both
R1490	T2072	T2073	det	these,QTL
R1491	T2073	T2071	pobj	QTL,of
R1492	T2074	T2034	acomp	suggestive,were
R1493	T2075	T2076	punct	(,10.9
R1494	T2076	T2074	parataxis	10.9,suggestive
R1495	T2077	T2076	nsubj	LRS,10.9
R1496	T2078	T2076	punct	>,10.9
R1497	T2079	T2076	punct	),10.9
R1498	T2080	T2034	cc	but,were
R1499	T2081	T2082	aux	did,reach
R1500	T2082	T2034	conj	reach,were
R1501	T2083	T2082	neg	not,reach
R1502	T2084	T2085	npadvmod	genome,wide
R1503	T2085	T2087	amod	wide,significance
R1504	T2086	T2085	punct	-,wide
R1505	T2087	T2082	dobj	significance,reach
R1506	T2088	T2089	punct	(,Figure
R1507	T2089	T2082	parataxis	Figure,reach
R1508	T2090	T2089	nummod	2B,Figure
R1513	T2113	T2114	det	a,marker
R1514	T2114	T2112	pobj	marker,to
R1515	T2115	T2114	amod	single,marker
R1516	T2116	T2114	punct	", ",marker
R1517	T2117	T2114	appos	D6Mit13,marker
R1518	T2118	T2119	punct	(,Figure
R1519	T2119	T2111	parataxis	Figure,ked
R1520	T2120	T2119	dep	Table,Figure
R1521	T2121	T2120	nummod	2,Table
R1522	T2122	T2119	punct	", ",Figure
R1523	T2123	T2119	nummod	3,Figure
R1524	T2124	T2119	punct	),Figure
R1525	T2125	T2111	punct	.,ked
R1526	T2127	T2128	amod	Adjacent,D6Mit254
R1527	T2128	T2131	nsubj	D6Mit254,are
R1528	T2129	T2128	amod	proximal,D6Mit254
R1529	T2130	T2128	compound	markers,D6Mit254
R1530	T2132	T2128	cc	and,D6Mit254
R1531	T2133	T2128	conj	D6Mit194,D6Mit254
R1532	T2134	T2131	acomp	unlinked,are
R1533	T2135	T2134	prep	to,unlinked
R1534	T2136	T2137	det	the,QTL
R1535	T2137	T2135	pobj	QTL,to
R1536	T2138	T2137	compound	QHCl,QTL
R1537	T2139	T2131	punct	", ",are
R1538	T2140	T2141	mark	as,is
R1539	T2141	T2131	advcl	is,are
R1540	T2142	T2143	amod	distal,marker
R1541	T2143	T2144	compound	marker,D6Mit374
R1542	T2144	T2141	nsubj	D6Mit374,is
R1543	T2145	T2131	punct	.,are
R1544	T2147	T2148	prep	Across,is
R1545	T2149	T2150	det	the,lines
R1546	T2150	T2147	pobj	lines,Across
R1547	T2151	T2150	nummod	17,lines
R1548	T2152	T2150	amod	RI,lines
R1549	T2153	T2150	acl	tested,lines
R1550	T2154	T2148	expl	there,is
R1551	T2155	T2156	advmod	at,one
R1552	T2156	T2158	nummod	one,event
R1553	T2157	T2156	advmod	least,one
R1554	T2158	T2148	attr	event,is
R1555	T2159	T2158	compound	recombination,event
R1556	T2160	T2158	prep	between,event
R1557	T2161	T2160	pobj	D6Mit13,between
R1558	T2162	T2161	cc	and,D6Mit13
R1559	T2163	T2164	preconj	either,D6Mit254
R1560	T2164	T2161	conj	D6Mit254,D6Mit13
R1561	T2165	T2164	punct	(,D6Mit254
R1562	T2166	T2164	cc	and,D6Mit254
R1563	T2167	T2164	conj	D6Mit194,D6Mit254
R1564	T2168	T2167	punct	", ",D6Mit194
R1565	T2169	T2170	det	the,position
R1566	T2170	T2172	dep	position,is
R1567	T2171	T2170	amod	physical,position
R1568	T2172	T2167	relcl	is,D6Mit194
R1569	T2173	T2170	prep	of,position
R1570	T2174	T2173	pobj	which,of
R1571	T2175	T2172	neg	not,is
R1572	T2176	T2177	advmod	well,defined
R1573	T2177	T2172	acomp	defined,is
R1574	T2178	T2164	punct	),D6Mit254
R1575	T2179	T2164	cc	or,D6Mit254
R1576	T2180	T2164	conj	D6Mit374,D6Mit254
R1577	T2181	T2148	punct	.,is
R1578	T2183	T2184	det	An,marker
R1579	T2184	T2187	nsubjpass	marker,identified
R1580	T2185	T2184	amod	additional,marker
R1581	T2186	T2184	amod	proximal,marker
R1582	T2188	T2184	punct	", ",marker
R1583	T2189	T2184	appos	D6Mit61,marker
R1584	T2190	T2184	punct	", ",marker
R1585	T2191	T2192	dep	which,lies
R1586	T2192	T2184	relcl	lies,marker
R1587	T2193	T2192	prep	between,lies
R1588	T2194	T2193	pobj	D6Mit194,between
R1589	T2195	T2194	cc	and,D6Mit194
R1590	T2196	T2194	conj	D6Mit13,D6Mit194
R1591	T2197	T2187	punct	", ",identified
R1592	T2198	T2187	auxpass	was,identified
R1593	T2199	T2187	prep	from,identified
R1594	T2200	T2199	pobj	genotypes,from
R1595	T2201	T2200	prep	of,genotypes
R1596	T2202	T2203	det	the,lines
R1597	T2203	T2201	pobj	lines,of
R1598	T2204	T2203	compound	BXD,lines
R1599	T2205	T2200	acl	reported,genotypes
R1600	T2206	T2205	agent	by,reported
R1601	T2207	T2208	det	the,Laboratories
R1602	T2208	T2206	pobj	Laboratories,by
R1603	T2209	T2208	compound	Jackson,Laboratories
R1604	T2210	T2187	punct	.,identified
R1605	T2212	T2213	nmod	BXD,mice
R1606	T2213	T2219	nsubj	mice,display
R1607	T2214	T2212	punct	/,BXD
R1608	T2215	T2212	appos	Ty,BXD
R1609	T2216	T2215	punct	-,Ty
R1610	T2217	T2215	nummod	34,Ty
R1611	T2218	T2213	amod	RI,mice
R1612	T2220	T2221	det	a,phenotype
R1613	T2221	T2219	dobj	phenotype,display
R1614	T2222	T2221	amod	clear,phenotype
R1615	T2223	T2221	compound	D2,phenotype
R1616	T2224	T2221	prep	for,phenotype
R1617	T2225	T2226	compound	QHCl,taste
R1618	T2226	T2224	pobj	taste,for
R1619	T2227	T2228	punct	(,Figure
R1620	T2228	T2221	parataxis	Figure,phenotype
R1621	T2229	T2228	nummod	1C,Figure
R1622	T2230	T2228	punct	),Figure
R1623	T2231	T2221	cc	and,phenotype
R1624	T2232	T2233	compound	D2,genotype
R1625	T2233	T2221	conj	genotype,phenotype
R1626	T2234	T2233	prep	for,genotype
R1627	T2235	T2234	pobj	D6Mit13,for
R1628	T2236	T2219	punct	", ",display
R1629	T2237	T2219	cc	but,display
R1630	T2238	T2219	conj	have,display
R1631	T2239	T2240	det	a,genotype
R1632	T2240	T2238	dobj	genotype,have
R1633	T2241	T2240	compound	B6,genotype
R1634	T2242	T2240	prep	for,genotype
R1635	T2243	T2242	pobj	D6Mit61,for
R1636	T2244	T2245	punct	[,40
R1637	T2245	T2240	parataxis	40,genotype
R1638	T2246	T2245	nummod	39,40
R1639	T2247	T2245	punct	",",40
R1640	T2248	T2245	punct	],40
R1641	T2249	T2238	punct	", ",have
R1642	T2250	T2238	advcl	indicating,have
R1643	T2251	T2252	mark	that,is
R1644	T2252	T2250	ccomp	is,indicating
R1645	T2253	T2252	nsubj	D6Mit61,is
R1646	T2254	T2252	acomp	unlinked,is
R1647	T2255	T2254	prep	to,unlinked
R1648	T2256	T2257	det	the,QTL
R1649	T2257	T2255	pobj	QTL,to
R1650	T2258	T2257	compound	QHCl,QTL
R1651	T2259	T2219	punct	.,display
R1652	T2261	T2262	advmod	Therefore,defined
R1653	T2263	T2262	punct	", ",defined
R1654	T2264	T2265	det	this,interval
R1655	T2265	T2262	nsubjpass	interval,defined
R1656	T2266	T2265	compound	QTL,interval
R1657	T2267	T2262	aux	can,defined
R1658	T2268	T2262	auxpass	be,defined
R1659	T2269	T2262	advmod	conservatively,defined
R1660	T2270	T2262	prep	as,defined
R1661	T2271	T2272	det	that,portion
R1662	T2272	T2270	pobj	portion,as
R1663	T2273	T2272	prep	of,portion
R1664	T2274	T2275	compound	mouse,chromosome
R1665	T2275	T2273	pobj	chromosome,of
R1666	T2276	T2275	nummod	6,chromosome
R1667	T2277	T2278	dep	that,lies
R1668	T2278	T2272	relcl	lies,portion
R1669	T2279	T2278	prep	between,lies
R1670	T2280	T2279	pobj	D6Mit254,between
R1671	T2281	T2280	cc	and,D6Mit254
R1672	T2282	T2280	conj	D6Mit374,D6Mit254
R1673	T2283	T2262	punct	", ",defined
R1674	T2284	T2262	cc	but,defined
R1675	T2285	T2286	auxpass	is,restricted
R1676	T2286	T2262	conj	restricted,defined
R1677	T2287	T2288	advmod	most,likely
R1678	T2288	T2286	advmod	likely,restricted
R1679	T2289	T2286	prep	to,restricted
R1680	T2290	T2291	det	the,region
R1681	T2291	T2289	pobj	region,to
R1682	T2292	T2291	prep	between,region
R1683	T2293	T2292	pobj	D6Mit61,between
R1684	T2294	T2293	cc	and,D6Mit61
R1685	T2295	T2293	conj	D6Mit374,D6Mit61
R1686	T2296	T2262	punct	.,defined
R1687	T2298	T2299	amod	Physical,mapping
R1688	T2299	T2300	nsubjpass	mapping,performed
R1689	T2301	T2299	prep	of,mapping
R1690	T2302	T2303	det	the,marker
R1691	T2303	T2301	pobj	marker,of
R1692	T2304	T2303	amod	single,marker
R1693	T2305	T2303	amod	linked,marker
R1694	T2306	T2303	punct	", ",marker
R1695	T2307	T2303	appos	D6Mit13,marker
R1696	T2308	T2299	punct	", ",mapping
R1697	T2309	T2299	cc	and,mapping
R1698	T2310	T2311	det	the,markers
R1699	T2311	T2299	conj	markers,mapping
R1700	T2312	T2311	nummod	two,markers
R1701	T2313	T2311	amod	closest,markers
R1702	T2314	T2311	amod	unlinked,markers
R1703	T2315	T2311	punct	", ",markers
R1704	T2316	T2317	dep	D6Mit61and,D6Mit374
R1705	T2317	T2311	nmod	D6Mit374,markers
R1706	T2318	T2300	punct	", ",performed
R1707	T2319	T2300	auxpass	was,performed
R1708	T2320	T2321	advmod	in,silico
R1709	T2321	T2300	advmod	silico,performed
R1710	T2322	T2300	prep	based,performed
R1711	T2323	T2322	prep	on,based
R1712	T2324	T2325	det	the,build
R1713	T2325	T2323	pobj	build,on
R1714	T2326	T2325	nmod	May,build
R1715	T2327	T2326	punct	", ",May
R1716	T2328	T2326	npadvmod	2004,May
R1717	T2329	T2325	prep	of,build
R1718	T2330	T2331	det	the,genome
R1719	T2331	T2329	pobj	genome,of
R1720	T2332	T2331	amod	public,genome
R1721	T2333	T2331	compound	B6,genome
R1722	T2334	T2300	punct	.,performed
R1723	T2336	T2337	prep	Based,is
R1724	T2338	T2336	prep	on,Based
R1725	T2339	T2340	det	these,positions
R1726	T2340	T2338	pobj	positions,on
R1727	T2341	T2340	compound	marker,positions
R1728	T2342	T2337	punct	", ",is
R1729	T2343	T2344	det	the,size
R1730	T2344	T2337	nsubj	size,is
R1731	T2345	T2344	prep	of,size
R1732	T2346	T2347	det	the,QTL
R1733	T2347	T2345	pobj	QTL,of
R1734	T2348	T2347	nmod	QHCl,QTL
R1735	T2349	T2347	nmod	chromosome,QTL
R1736	T2350	T2349	nummod	6,chromosome
R1737	T2351	T2352	amod	less,5.0
R1738	T2352	T2354	nummod	5.0,Mb
R1739	T2353	T2352	quantmod	than,5.0
R1740	T2354	T2337	attr	Mb,is
R1741	T2355	T2356	punct	(,Figure
R1742	T2356	T2337	parataxis	Figure,is
R1743	T2357	T2356	nummod	3,Figure
R1744	T2358	T2356	punct	),Figure
R1745	T2359	T2337	punct	.,is
R1746	T2361	T2362	det	This,region
R1747	T2362	T2363	nsubj	region,contains
R1748	T2364	T2365	det	a,number
R1749	T2365	T2363	dobj	number,contains
R1750	T2366	T2365	prep	of,number
R1751	T2367	T2368	amod	known,genes
R1752	T2368	T2366	pobj	genes,of
R1753	T2369	T2365	punct	", ",number
R1754	T2370	T2371	dep	all,encode
R1755	T2371	T2365	relcl	encode,number
R1756	T2372	T2370	prep	but,all
R1757	T2373	T2372	pobj	eleven,but
R1758	T2374	T2370	prep	of,all
R1759	T2375	T2374	pobj	which,of
R1760	T2376	T2371	dobj	members,encode
R1761	T2377	T2376	prep	of,members
R1762	T2378	T2379	nummod	two,families
R1763	T2379	T2377	pobj	families,of
R1764	T2380	T2379	amod	large,families
R1765	T2381	T2379	compound	receptor,families
R1766	T2382	T2379	punct	: ,families
R1767	T2383	T2384	amod	natural,cell
R1768	T2384	T2386	nmod	cell,receptors
R1769	T2385	T2384	nmod	killer,cell
R1770	T2386	T2379	appos	receptors,families
R1771	T2387	T2388	npadvmod	lectin,like
R1772	T2388	T2386	amod	like,receptors
R1773	T2389	T2388	punct	-,like
R1774	T2390	T2386	punct	", ",receptors
R1775	T2391	T2386	cc	and,receptors
R1776	T2392	T2393	compound	T2R,type
R1777	T2393	T2395	compound	type,receptors
R1778	T2394	T2393	punct	-,type
R1779	T2395	T2386	conj	receptors,receptors
R1780	T2396	T2395	compound	taste,receptors
R1781	T2397	T2363	punct	.,contains
R1782	T2399	T2400	det	The,genes
R1783	T2400	T2402	nsubjpass	genes,found
R1784	T2401	T2400	compound	Tas2r,genes
R1785	T2403	T2400	punct	(,genes
R1786	T2404	T2405	dep	which,encode
R1787	T2405	T2400	relcl	encode,genes
R1788	T2406	T2407	det	the,T2Rs
R1789	T2407	T2405	dobj	T2Rs,encode
R1790	T2408	T2402	punct	),found
R1791	T2409	T2402	auxpass	are,found
R1792	T2410	T2402	xcomp	clustered,found
R1793	T2411	T2410	prep	within,clustered
R1794	T2412	T2413	det	a,interval
R1795	T2413	T2411	pobj	interval,within
R1796	T2414	T2415	nummod	1.2,Mb
R1797	T2415	T2413	compound	Mb,interval
R1798	T2416	T2413	prep	on,interval
R1799	T2417	T2418	det	either,side
R1800	T2418	T2416	pobj	side,on
R1801	T2419	T2418	prep	of,side
R1802	T2420	T2419	pobj	D6Mit13,of
R1803	T2421	T2422	punct	(,Figure
R1804	T2422	T2410	parataxis	Figure,clustered
R1805	T2423	T2422	dep	Figure,Figure
R1806	T2424	T2423	nummod	3,Figure
R1807	T2425	T2422	punct	", ",Figure
R1808	T2426	T2422	nummod	4,Figure
R1809	T2427	T2422	punct	),Figure
R1810	T2428	T2402	punct	.,found
R1811	T2430	T2431	prep	Because,hypothesized
R1812	T2432	T2430	pcomp	of,Because
R1813	T2433	T2434	poss	their,proximity
R1814	T2434	T2430	pobj	proximity,Because
R1815	T2435	T2434	prep	to,proximity
R1816	T2436	T2437	det	the,marker
R1817	T2437	T2435	pobj	marker,to
R1818	T2438	T2437	amod	linked,marker
R1819	T2439	T2434	punct	", ",proximity
R1820	T2440	T2441	poss	their,expression
R1821	T2441	T2434	conj	expression,proximity
R1822	T2442	T2441	amod	demonstrated,expression
R1823	T2443	T2441	prep	in,expression
R1824	T2444	T2445	compound	taste,cells
R1825	T2445	T2443	pobj	cells,in
R1826	T2446	T2445	compound	receptor,cells
R1827	T2447	T2441	punct	", ",expression
R1828	T2448	T2441	cc	and,expression
R1829	T2449	T2450	poss	their,role
R1830	T2450	T2441	conj	role,expression
R1831	T2451	T2450	prep	in,role
R1832	T2452	T2453	det	the,detection
R1833	T2453	T2451	pobj	detection,in
R1834	T2454	T2453	prep	of,detection
R1835	T2455	T2456	advmod	at,least
R1836	T2456	T2457	advmod	least,compounds
R1837	T2457	T2454	pobj	compounds,of
R1838	T2458	T2457	det	some,compounds
R1839	T2459	T2460	amod	bitter,tasting
R1840	T2460	T2457	amod	tasting,compounds
R1841	T2461	T2460	punct	-,tasting
R1842	T2462	T2431	punct	", ",hypothesized
R1843	T2463	T2431	nsubj	we,hypothesized
R1844	T2464	T2465	mark	that,were
R1845	T2465	T2431	ccomp	were,hypothesized
R1846	T2466	T2465	nsubj	one,were
R1847	T2467	T2466	cc	or,one
R1848	T2468	T2466	conj	more,one
R1849	T2469	T2466	prep	of,one
R1850	T2470	T2471	det	the,Tas2rs
R1851	T2471	T2469	pobj	Tas2rs,of
R1852	T2472	T2471	nummod	24,Tas2rs
R1853	T2473	T2466	prep	at,one
R1854	T2474	T2475	det	this,locus
R1855	T2475	T2473	pobj	locus,at
R1856	T2476	T2465	acomp	responsible,were
R1857	T2477	T2476	prep	for,responsible
R1858	T2478	T2479	det	the,QTL
R1859	T2479	T2477	pobj	QTL,for
R1860	T2480	T2479	amod	major,QTL
R1861	T2481	T2479	compound	QHCl,QTL
R1862	T2482	T2483	compound	taste,sensitivity
R1863	T2483	T2479	compound	sensitivity,QTL
R1864	T2484	T2431	punct	.,hypothesized
R1865	T2700	T2701	compound	T2R,alleles
R1866	T2703	T2704	mark	If,underlie
R1867	T2704	T2711	advcl	underlie,predict
R1868	T2705	T2706	nummod	one,Tas2rs
R1869	T2706	T2704	nsubj	Tas2rs,underlie
R1870	T2707	T2705	punct	(,one
R1871	T2708	T2705	cc	or,one
R1872	T2709	T2705	conj	more,one
R1873	T2710	T2706	punct	),Tas2rs
R1874	T2711	T2722	ccomp	predict,affects
R1875	T2712	T2713	det	the,QTL
R1876	T2713	T2704	dobj	QTL,underlie
R1877	T2714	T2713	nmod	chromosome,QTL
R1878	T2715	T2714	nummod	6,chromosome
R1879	T2716	T2713	compound	QHCl,QTL
R1880	T2717	T2718	compound	taste,sensitivity
R1881	T2718	T2713	compound	sensitivity,QTL
R1882	T2719	T2711	punct	", ",predict
R1883	T2720	T2711	nsubj	we,predict
R1884	T2721	T2711	aux	would,predict
R1885	T2723	T2724	mark	that,exhibit
R1886	T2724	T2711	ccomp	exhibit,predict
R1887	T2725	T2726	nummod	one,genes
R1888	T2726	T2724	nsubj	genes,exhibit
R1889	T2727	T2725	punct	(,one
R1890	T2728	T2725	cc	or,one
R1891	T2729	T2725	conj	more,one
R1892	T2730	T2726	punct	),genes
R1893	T2731	T2726	compound	Tas2r,genes
R1894	T2732	T2724	aux	would,exhibit
R1895	T2733	T2724	dobj	one,exhibit
R1896	T2734	T2733	prep	of,one
R1897	T2735	T2736	nummod	three,characteristics
R1898	T2736	T2734	pobj	characteristics,of
R1899	T2737	T2736	amod	likely,characteristics
R1900	T2738	T2722	punct	: ,affects
R1901	T2739	T2740	punct	(,1
R1902	T2740	T2741	meta	1,is
R1903	T2741	T2722	ccomp	is,affects
R1904	T2742	T2740	punct	),1
R1905	T2743	T2744	compound	A,allele
R1906	T2744	T2741	nsubj	allele,is
R1907	T2745	T2744	compound	Tas2r,allele
R1908	T2746	T2747	det	a,pseudogene
R1909	T2747	T2741	attr	pseudogene,is
R1910	T2748	T2741	punct	", ",is
R1911	T2749	T2741	cc	or,is
R1912	T2750	T2751	auxpass	is,deleted
R1913	T2751	T2741	conj	deleted,is
R1914	T2752	T2751	punct	", ",deleted
R1915	T2753	T2751	prep	in,deleted
R1916	T2754	T2755	nmod	D2,mice
R1917	T2755	T2753	pobj	mice,in
R1918	T2756	T2757	punct	(,insensitive
R1919	T2757	T2754	parataxis	insensitive,D2
R1920	T2758	T2757	npadvmod	QHCL,insensitive
R1921	T2759	T2757	punct	-,insensitive
R1922	T2760	T2757	punct	),insensitive
R1923	T2761	T2754	punct	", ",D2
R1924	T2762	T2754	cc	but,D2
R1925	T2763	T2762	neg	not,but
R1926	T2764	T2754	conj	B6,D2
R1927	T2765	T2766	punct	(,sensitive
R1928	T2766	T2764	parataxis	sensitive,B6
R1929	T2767	T2766	npadvmod	QHCl,sensitive
R1930	T2768	T2766	punct	-,sensitive
R1931	T2769	T2766	punct	),sensitive
R1932	T2770	T2755	punct	", ",mice
R1933	T2771	T2722	punct	;,affects
R1934	T2772	T2773	punct	(,2
R1935	T2773	T2774	meta	2,impact
R1936	T2774	T2722	ccomp	impact,affects
R1937	T2775	T2773	punct	),2
R1938	T2776	T2777	compound	Missense,mutations
R1939	T2777	T2774	nsubj	mutations,impact
R1940	T2778	T2777	prep	in,mutations
R1941	T2779	T2780	det	the,exon
R1942	T2780	T2778	pobj	exon,in
R1943	T2781	T2780	amod	single,exon
R1944	T2782	T2780	amod	coding,exon
R1945	T2783	T2780	prep	of,exon
R1946	T2784	T2785	det	a,allele
R1947	T2785	T2783	pobj	allele,of
R1948	T2786	T2785	compound	D2,allele
R1949	T2787	T2785	compound	Tas2r,allele
R1950	T2788	T2789	compound	protein,functions
R1951	T2789	T2774	dobj	functions,impact
R1952	T2790	T2791	amod	such,as
R1953	T2791	T2789	prep	as,functions
R1954	T2792	T2793	compound	ligand,binding
R1955	T2793	T2791	pobj	binding,as
R1956	T2794	T2793	cc	or,binding
R1957	T2795	T2796	compound	receptor,coupling
R1958	T2796	T2793	conj	coupling,binding
R1959	T2797	T2796	prep	to,coupling
R1960	T2798	T2799	amod	downstream,cascades
R1961	T2799	T2797	pobj	cascades,to
R1962	T2800	T2799	compound	signaling,cascades
R1963	T2801	T2722	punct	;,affects
R1964	T2802	T2803	punct	(,3
R1965	T2803	T2722	meta	3,affects
R1966	T2804	T2803	punct	),3
R1967	T2805	T2722	nsubj	Mutations,affects
R1968	T2806	T2805	prep	in,Mutations
R1969	T2807	T2808	amod	noncoding,regions
R1970	T2808	T2806	pobj	regions,in
R1971	T2809	T2807	cc	or,noncoding
R1972	T2810	T2807	conj	regulatory,noncoding
R1973	T2811	T2808	prep	of,regions
R1974	T2812	T2813	det	a,allele
R1975	T2813	T2811	pobj	allele,of
R1976	T2814	T2813	compound	D2,allele
R1977	T2815	T2813	compound	Tas2r,allele
R1978	T2816	T2722	dobj	expression,affects
R1979	T2817	T2816	prep	of,expression
R1980	T2818	T2819	det	the,product
R1981	T2819	T2817	pobj	product,of
R1982	T2820	T2819	compound	protein,product
R1983	T2821	T2722	punct	.,affects
R1984	T2823	T2824	mark	Though,considered
R1985	T2824	T2826	advcl	considered,focused
R1986	T2825	T2824	nsubj	we,considered
R1987	T2827	T2828	det	all,three
R1988	T2828	T2829	nsubj	three,be
R1989	T2829	T2824	ccomp	be,considered
R1990	T2830	T2828	prep	of,three
R1991	T2831	T2830	pobj	these,of
R1992	T2832	T2829	aux	to,be
R1993	T2833	T2834	amod	valid,possibilities
R1994	T2834	T2829	attr	possibilities,be
R1995	T2835	T2826	punct	", ",focused
R1996	T2836	T2826	nsubj	we,focused
R1997	T2837	T2826	advmod	initially,focused
R1998	T2838	T2826	prep	on,focused
R1999	T2839	T2840	det	the,likelihood
R2000	T2840	T2838	pobj	likelihood,on
R2001	T2841	T2842	mark	that,correlate
R2002	T2842	T2840	acl	correlate,likelihood
R2003	T2843	T2842	nsubj	deletion,correlate
R2004	T2844	T2843	cc	or,deletion
R2005	T2845	T2843	conj	mutation,deletion
R2006	T2846	T2843	prep	within,deletion
R2007	T2847	T2848	det	the,sequence
R2008	T2848	T2846	pobj	sequence,within
R2009	T2849	T2848	amod	coding,sequence
R2010	T2850	T2848	prep	of,sequence
R2011	T2851	T2852	det	a,Tas2r
R2012	T2852	T2850	pobj	Tas2r,of
R2013	T2853	T2852	amod	single,Tas2r
R2014	T2854	T2852	compound	D2,Tas2r
R2015	T2855	T2842	aux	would,correlate
R2016	T2856	T2842	prep	with,correlate
R2017	T2857	T2858	det	the,phenotype
R2018	T2858	T2856	pobj	phenotype,with
R2019	T2859	T2860	compound	QHCl,taste
R2020	T2860	T2861	compound	taste,insensitivity
R2021	T2861	T2858	compound	insensitivity,phenotype
R2022	T2862	T2826	punct	.,focused
R2023	T2864	T2865	compound	Twenty,four
R2024	T2865	T2867	nummod	four,Tas2rs
R2025	T2866	T2865	punct	-,four
R2026	T2867	T2869	nsubjpass	Tas2rs,identified
R2027	T2868	T2867	amod	intact,Tas2rs
R2028	T2870	T2867	punct	", ",Tas2rs
R2029	T2871	T2867	prep	along,Tas2rs
R2030	T2872	T2871	prep	with,along
R2031	T2873	T2874	nummod	three,pseudogenes
R2032	T2874	T2872	pobj	pseudogenes,with
R2033	T2875	T2874	amod	apparent,pseudogenes
R2034	T2876	T2874	compound	Tas2r,pseudogenes
R2035	T2877	T2869	punct	", ",identified
R2036	T2878	T2869	aux	have,identified
R2037	T2879	T2869	auxpass	been,identified
R2038	T2880	T2869	prep	in,identified
R2039	T2881	T2882	det	the,cluster
R2040	T2882	T2880	pobj	cluster,in
R2041	T2883	T2882	amod	distal,cluster
R2042	T2884	T2882	nmod	chromosome,cluster
R2043	T2885	T2884	nummod	6,chromosome
R2044	T2886	T2882	prep	of,cluster
R2045	T2887	T2888	compound	B6,mice
R2046	T2888	T2886	pobj	mice,of
R2047	T2889	T2890	punct	[,19
R2048	T2890	T2869	parataxis	19,identified
R2049	T2891	T2890	punct	],19
R2050	T2892	T2893	punct	(,Figure
R2051	T2893	T2869	parataxis	Figure,identified
R2052	T2894	T2893	nummod	4,Figure
R2053	T2895	T2893	punct	),Figure
R2054	T2896	T2869	punct	.,identified
R2055	T2898	T2899	nsubj	We,designed
R2056	T2900	T2899	dobj	oligonucleotides,designed
R2057	T2901	T2900	prep	to,oligonucleotides
R2058	T2902	T2903	amod	non-coding,regions
R2059	T2903	T2901	pobj	regions,to
R2060	T2904	T2903	acl	flanking,regions
R2061	T2905	T2906	det	the,sequence
R2062	T2906	T2904	dobj	sequence,flanking
R2063	T2907	T2906	compound	coding,sequence
R2064	T2908	T2906	prep	of,sequence
R2065	T2909	T2910	det	each,Tas2r
R2066	T2910	T2908	pobj	Tas2r,of
R2067	T2911	T2910	amod	intact,Tas2r
R2068	T2912	T2913	punct	[,see
R2069	T2913	T2899	parataxis	see,designed
R2070	T2914	T2915	amod	Additional,file
R2071	T2915	T2913	dobj	file,see
R2072	T2916	T2915	nummod	2,file
R2073	T2917	T2913	punct	],see
R2074	T2918	T2899	punct	.,designed
R2075	T2920	T2921	advcl	Using,amplified
R2076	T2922	T2923	det	these,oligos
R2077	T2923	T2920	dobj	oligos,Using
R2078	T2924	T2921	punct	", ",amplified
R2079	T2925	T2921	nsubj	we,amplified
R2080	T2926	T2927	det	each,sequence
R2081	T2927	T2921	dobj	sequence,amplified
R2082	T2928	T2927	compound	Tas2r,sequence
R2083	T2929	T2927	compound	coding,sequence
R2084	T2930	T2921	prep	from,amplified
R2085	T2931	T2932	nmod	D2,DNA
R2086	T2932	T2930	pobj	DNA,from
R2087	T2933	T2932	amod	genomic,DNA
R2088	T2934	T2921	punct	.,amplified
R2089	T2936	T2937	compound	PCR,products
R2090	T2937	T2938	nsubjpass	products,subcloned
R2091	T2939	T2938	auxpass	were,subcloned
R2092	T2940	T2938	prep	into,subcloned
R2093	T2941	T2942	compound	cloning,vectors
R2094	T2942	T2940	pobj	vectors,into
R2095	T2943	T2938	cc	and,subcloned
R2096	T2944	T2938	conj	sequenced,subcloned
R2097	T2945	T2938	punct	.,subcloned
R2098	T2947	T2948	nsubj	Comparisons,revealed
R2099	T2949	T2947	prep	of,Comparisons
R2100	T2950	T2951	det	the,sequences
R2101	T2951	T2949	pobj	sequences,of
R2102	T2952	T2951	prep	of,sequences
R2103	T2953	T2954	nmod	B6,orthologues
R2104	T2954	T2952	pobj	orthologues,of
R2105	T2955	T2953	cc	and,B6
R2106	T2956	T2953	conj	D2,B6
R2107	T2957	T2958	mark	that,were
R2108	T2958	T2948	ccomp	were,revealed
R2109	T2959	T2960	advmod	only,two
R2110	T2960	T2958	nsubj	two,were
R2111	T2961	T2960	prep	of,two
R2112	T2962	T2963	det	the,alleles
R2113	T2963	T2961	pobj	alleles,of
R2114	T2964	T2965	compound	twenty,four
R2115	T2965	T2963	nummod	four,alleles
R2116	T2966	T2965	punct	-,four
R2117	T2967	T2963	compound	Tas2r,alleles
R2118	T2968	T2963	acl	examined,alleles
R2119	T2969	T2960	punct	", ",two
R2120	T2970	T2960	appos	Tas2r106,two
R2121	T2971	T2970	cc	and,Tas2r106
R2122	T2972	T2970	conj	Tas2r124,Tas2r106
R2123	T2973	T2958	punct	", ",were
R2124	T2974	T2958	acomp	identical,were
R2125	T2975	T2958	prep	across,were
R2126	T2976	T2975	pobj	strains,across
R2127	T2977	T2958	prep	at,were
R2128	T2978	T2979	det	the,level
R2129	T2979	T2977	pobj	level,at
R2130	T2980	T2981	compound	amino,acid
R2131	T2981	T2979	compound	acid,level
R2132	T2982	T2983	punct	(,shown
R2133	T2983	T2958	parataxis	shown,were
R2134	T2984	T2983	nsubj	data,shown
R2135	T2985	T2983	neg	not,shown
R2136	T2986	T2983	punct	),shown
R2137	T2987	T2948	punct	.,revealed
R2138	T2989	T2990	det	A,third
R2139	T2990	T2991	nsubjpass	third,amplified
R2140	T2992	T2990	punct	", ",third
R2141	T2993	T2990	appos	Tas2r120,third
R2142	T2994	T2991	punct	", ",amplified
R2143	T2995	T2991	aux	could,amplified
R2144	T2996	T2991	neg	not,amplified
R2145	T2997	T2991	auxpass	be,amplified
R2146	T2998	T2991	prep	from,amplified
R2147	T2999	T3000	nmod	D2,DNA
R2148	T3000	T2998	pobj	DNA,from
R2149	T3001	T3000	amod	genomic,DNA
R2150	T3002	T3003	punct	(,Figure
R2151	T3003	T3000	parataxis	Figure,DNA
R2152	T3004	T3003	nummod	5,Figure
R2153	T3005	T3003	punct	),Figure
R2154	T3006	T2991	advcl	using,amplified
R2155	T3007	T3006	dobj	either,using
R2156	T3008	T3007	prep	of,either
R2157	T3009	T3010	nummod	two,pairs
R2158	T3010	T3008	pobj	pairs,of
R2159	T3011	T3010	prep	of,pairs
R2160	T3012	T3011	pobj	oligonucleotides,of
R2161	T3013	T3014	punct	(,file
R2162	T3014	T3006	parataxis	file,using
R2163	T3015	T3014	amod	Additional,file
R2164	T3016	T3014	nummod	2,file
R2165	T3017	T3014	punct	),file
R2166	T3018	T2991	punct	", ",amplified
R2167	T3019	T2991	advcl	suggesting,amplified
R2168	T3020	T3021	mark	that,deleted
R2169	T3021	T3019	ccomp	deleted,suggesting
R2170	T3022	T3023	det	this,Tas2r
R2171	T3023	T3021	nsubjpass	Tas2r,deleted
R2172	T3024	T3021	auxpass	is,deleted
R2173	T3025	T3021	prep	in,deleted
R2174	T3026	T3027	compound	D2,mice
R2175	T3027	T3025	pobj	mice,in
R2176	T3028	T2991	punct	.,amplified
R2177	T3030	T3031	nummod	Two,alleles
R2178	T3031	T3033	nsubj	alleles,contained
R2179	T3032	T3031	compound	D2,alleles
R2180	T3033	T3039	ccomp	contained,be
R2181	T3034	T3031	punct	", ",alleles
R2182	T3035	T3031	appos	Tas2r103,alleles
R2183	T3036	T3035	cc	and,Tas2r103
R2184	T3037	T3035	conj	Tas2r117,Tas2r103
R2185	T3038	T3033	punct	", ",contained
R2186	T3040	T3041	amod	numerous,mutations
R2187	T3041	T3033	dobj	mutations,contained
R2188	T3042	T3041	compound	missense,mutations
R2189	T3043	T3041	cc	and,mutations
R2190	T3044	T3045	amod	small,deletions
R2191	T3045	T3041	conj	deletions,mutations
R2192	T3046	T3047	dep	that,create
R2193	T3047	T3045	relcl	create,deletions
R2194	T3048	T3049	compound	frame,shifts
R2195	T3049	T3047	dobj	shifts,create
R2196	T3050	T3049	cc	and,shifts
R2197	T3051	T3052	amod	premature,termination
R2198	T3052	T3049	conj	termination,shifts
R2199	T3053	T3039	punct	;,be
R2200	T3054	T3055	det	these,genes
R2201	T3055	T3039	nsubj	genes,be
R2202	T3056	T3055	nummod	two,genes
R2203	T3057	T3039	aux	may,be
R2204	T3058	T3039	attr	pseudogenes,be
R2205	T3059	T3039	prep	in,be
R2206	T3060	T3061	det	this,strain
R2207	T3061	T3059	pobj	strain,in
R2208	T3062	T3039	punct	.,be
R2209	T3064	T3065	det	The,Tas2rs
R2210	T3065	T3068	nsubj	Tas2rs,contained
R2211	T3066	T3065	amod	remaining,Tas2rs
R2212	T3067	T3065	nummod	19,Tas2rs
R2213	T3069	T3070	quantmod	between,one
R2214	T3070	T3071	nummod	one,mutations
R2215	T3071	T3068	dobj	mutations,contained
R2216	T3072	T3070	cc	and,one
R2217	T3073	T3070	conj	16,one
R2218	T3074	T3071	compound	missense,mutations
R2219	T3075	T3068	punct	.,contained
R2220	T3077	T3078	det	All,Tas2rs
R2221	T3078	T3080	nsubj	Tas2rs,have
R2222	T3079	T3078	nummod	24,Tas2rs
R2223	T3081	T3078	acl	examined,Tas2rs
R2224	T3082	T3083	amod	different,alleles
R2225	T3083	T3080	dobj	alleles,have
R2226	T3084	T3080	prep	in,have
R2227	T3085	T3086	nmod	B6,mice
R2228	T3086	T3084	pobj	mice,in
R2229	T3087	T3085	cc	and,B6
R2230	T3088	T3085	conj	D2,B6
R2231	T3089	T3080	punct	", ",have
R2232	T3090	T3080	cc	and,have
R2233	T3091	T3092	nummod	307,polymorphisms
R2234	T3092	T3095	nsubj	polymorphisms,are
R2235	T3093	T3092	amod	single,polymorphisms
R2236	T3094	T3092	compound	nucleotide,polymorphisms
R2237	T3095	T3080	conj	are,have
R2238	T3096	T3095	acomp	present,are
R2239	T3097	T3095	prep	within,are
R2240	T3098	T3099	compound	coding,exons
R2241	T3099	T3097	pobj	exons,within
R2242	T3100	T3101	punct	(,shown
R2243	T3101	T3095	parataxis	shown,are
R2244	T3102	T3101	nsubj	data,shown
R2245	T3103	T3101	neg	not,shown
R2246	T3104	T3101	punct	),shown
R2247	T3105	T3095	punct	.,are
R2248	T3107	T3108	mark	Although,found
R2250	T3109	T3110	amod	polymorphic,residues
R2251	T3110	T3108	nsubjpass	residues,found
R2252	T3111	T3110	prep	between,residues
R2253	T3112	T3113	nmod	B6,Tas2rs
R2255	T3114	T3112	cc	and,B6
R2256	T3115	T3112	conj	D2,B6
R2326	T3195	T3193	nsubj	we,proceeded
R2327	T3196	T3197	aux	to,screen
R2328	T3197	T3193	xcomp	screen,proceeded
R2329	T3198	T3199	amod	genomic,DNA
R2330	T3199	T3197	dobj	DNA,screen
R2331	T3200	T3199	prep	from,DNA
R2332	T3201	T3202	nummod	29,lines
R2333	T3202	T3200	pobj	lines,from
R2334	T3203	T3202	amod	available,lines
R2335	T3204	T3202	nmod	BXD,lines
R2336	T3205	T3202	amod	RI,lines
R2337	T3206	T3202	punct	", ",lines
R2338	T3207	T3202	prep	including,lines
R2339	T3208	T3209	det	the,17
R2340	T3209	T3207	pobj	17,including
R2341	T3210	T3211	dep	that,used
R2342	T3211	T3209	relcl	used,17
R2343	T3212	T3211	nsubj	we,used
R2344	T3213	T3211	aux	had,used
R2345	T3214	T3211	prep	in,used
R2346	T3215	T3216	compound	taste,testing
R2347	T3216	T3214	pobj	testing,in
R2348	T3217	T3197	punct	", ",screen
R2349	T3218	T3197	prep	for,screen
R2350	T3219	T3220	det	the,Tas2r
R2351	T3220	T3218	pobj	Tas2r,for
R2352	T3221	T3220	nmod	alleles,Tas2r
R2353	T3222	T3223	nsubj	they,contained
R2354	T3223	T3220	advcl	contained,Tas2r
R2355	T3224	T3193	punct	.,proceeded
R2356	T3226	T3227	prep	In,were
R2357	T3228	T3229	amod	most,cases
R2358	T3229	T3226	pobj	cases,In
R2359	T3230	T3227	punct	", ",were
R2360	T3231	T3227	nsubj	we,were
R2361	T3232	T3227	acomp	able,were
R2362	T3233	T3234	aux	to,identify
R2363	T3234	T3232	xcomp	identify,able
R2364	T3235	T3236	amod	diagnostic,digests
R2365	T3236	T3234	dobj	digests,identify
R2366	T3237	T3236	compound	restriction,digests
R2367	T3238	T3236	compound	endonuclease,digests
R2368	T3239	T3240	dep	that,allow
R2369	T3240	T3236	relcl	allow,digests
R2370	T3241	T3240	aux	would,allow
R2371	T3242	T3243	nsubj	us,identify
R2372	T3243	T3240	ccomp	identify,allow
R2373	T3244	T3243	aux	to,identify
R2374	T3245	T3243	advmod	quickly,identify
R2375	T3246	T3247	mark	whether,amplified
R2376	T3247	T3243	ccomp	amplified,identify
R2377	T3248	T3249	det	a,product
R2378	T3249	T3247	nsubjpass	product,amplified
R2379	T3250	T3249	amod	particular,product
R2380	T3251	T3249	compound	Tas2r,product
R2381	T3252	T3249	compound	PCR,product
R2382	T3253	T3247	auxpass	was,amplified
R2383	T3254	T3247	prep	from,amplified
R2384	T3255	T3256	det	a,allele
R2385	T3256	T3254	pobj	allele,from
R2386	T3257	T3256	nmod	B6,allele
R2387	T3258	T3257	cc	or,B6
R2388	T3259	T3257	conj	D2,B6
R2389	T3260	T3227	punct	.,were
R2390	T3262	T3263	nsubj	We,analyze
R2391	T3264	T3263	aux	did,analyze
R2392	T3265	T3263	neg	not,analyze
R2393	T3266	T3267	nummod	three,genes
R2394	T3267	T3263	dobj	genes,analyze
R2395	T3268	T3267	punct	(,genes
R2396	T3269	T3267	appos	Tas2r104,genes
R2397	T3270	T3269	punct	", ",Tas2r104
R2398	T3271	T3269	conj	Tas2r114,Tas2r104
R2399	T3272	T3271	cc	and,Tas2r114
R2400	T3273	T3271	conj	Tas2r110,Tas2r114
R2401	T3274	T3267	punct	),genes
R2402	T3275	T3276	advmod	where,identified
R2403	T3276	T3267	relcl	identified,genes
R2404	T3277	T3278	det	no,endonuclease
R2405	T3278	T3276	nsubjpass	endonuclease,identified
R2406	T3279	T3278	amod	diagnostic,endonuclease
R2407	T3280	T3278	compound	restriction,endonuclease
R2408	T3281	T3276	aux	could,identified
R2409	T3282	T3276	auxpass	be,identified
R2410	T3283	T3263	punct	.,analyze
R2411	T3285	T3286	prep	For,was
R2412	T3287	T3285	pobj	Tas2r120,For
R2413	T3288	T3287	punct	", ",Tas2r120
R2414	T3289	T3290	dep	which,deleted
R2415	T3290	T3287	relcl	deleted,Tas2r120
R2416	T3291	T3290	auxpass	is,deleted
R2417	T3292	T3290	advmod	likely,deleted
R2418	T3293	T3290	prep	in,deleted
R2419	T3294	T3295	compound	D2,mice
R2420	T3295	T3293	pobj	mice,in
R2421	T3296	T3286	punct	", ",was
R2422	T3297	T3298	det	the,absence
R2423	T3298	T3286	nsubj	absence,was
R2424	T3299	T3298	prep	of,absence
R2425	T3300	T3301	det	a,product
R2426	T3301	T3299	pobj	product,of
R2427	T3302	T3301	compound	PCR,product
R2428	T3303	T3286	acomp	diagnostic,was
R2429	T3304	T3303	prep	of,diagnostic
R2430	T3305	T3306	det	the,genotype
R2431	T3306	T3304	pobj	genotype,of
R2432	T3307	T3306	compound	D2,genotype
R2433	T3308	T3306	prep	for,genotype
R2434	T3309	T3310	det	this,gene
R2435	T3310	T3308	pobj	gene,for
R2436	T3311	T3286	punct	.,was
R2437	T3313	T3314	advmod	Surprisingly,discovered
R2438	T3315	T3314	punct	", ",discovered
R2439	T3316	T3314	nsubj	we,discovered
R2440	T3317	T3318	mark	that,been
R2441	T3318	T3314	ccomp	been,discovered
R2442	T3319	T3318	expl	there,been
R2443	T3320	T3318	aux	have,been
R2444	T3321	T3322	det	no,events
R2445	T3322	T3318	attr	events,been
R2446	T3323	T3322	amod	apparent,events
R2447	T3324	T3322	compound	recombination,events
R2448	T3325	T3322	prep	within,events
R2449	T3326	T3327	det	the,cluster
R2450	T3327	T3325	pobj	cluster,within
R2451	T3328	T3327	amod	distal,cluster
R2452	T3329	T3327	nmod	chromosome,cluster
R2453	T3330	T3329	nummod	6,chromosome
R2454	T3331	T3318	prep	during,been
R2455	T3332	T3333	det	the,generation
R2456	T3333	T3331	pobj	generation,during
R2457	T3334	T3333	prep	of,generation
R2458	T3335	T3336	det	the,lines
R2459	T3336	T3334	pobj	lines,of
R2460	T3337	T3336	nmod	BXD,lines
R2461	T3338	T3336	amod	RI,lines
R2462	T3339	T3314	punct	.,discovered
R2463	T3341	T3342	prep	For,originated
R2464	T3343	T3344	det	all,lines
R2465	T3344	T3341	pobj	lines,For
R2466	T3345	T3344	amod	RI,lines
R2467	T3346	T3344	acl	tested,lines
R2468	T3347	T3342	punct	", ",originated
R2469	T3348	T3349	det	every,Tas2r
R2470	T3349	T3342	nsubj	Tas2r,originated
R2471	T3350	T3349	prep	within,Tas2r
R2472	T3351	T3352	det	an,line
R2473	T3352	T3350	pobj	line,within
R2474	T3353	T3352	amod	individual,line
R2475	T3354	T3352	amod	RI,line
R2476	T3355	T3342	prep	from,originated
R2477	T3356	T3357	det	the,strain
R2478	T3357	T3355	pobj	strain,from
R2479	T3358	T3357	amod	same,strain
R2480	T3359	T3357	amod	parental,strain
R2481	T3360	T3361	punct	(,6
R2482	T3361	T3342	parataxis	6,originated
R2483	T3362	T3361	nmod	Figures,6
R2484	T3363	T3361	nummod	5,6
R2485	T3364	T3361	punct	", ",6
R2486	T3365	T3361	punct	),6
R2487	T3366	T3342	punct	.,originated
R2488	T3368	T3369	advmod	Furthermore,correlated
R2489	T3370	T3369	punct	", ",correlated
R2490	T3371	T3372	det	the,genotype
R2491	T3372	T3369	nsubj	genotype,correlated
R2492	T3373	T3372	prep	of,genotype
R2493	T3374	T3375	det	each,gene
R2494	T3375	T3373	pobj	gene,of
R2495	T3376	T3375	compound	Tas2r,gene
R2496	T3377	T3369	advmod	always,correlated
R2497	T3378	T3369	prep	with,correlated
R2498	T3379	T3380	det	the,phenotype
R2499	T3380	T3378	pobj	phenotype,with
R2500	T3381	T3380	compound	QHCl,phenotype
R2501	T3382	T3380	compound	taste,phenotype
R2502	T3383	T3384	punct	(,7
R2503	T3384	T3369	parataxis	7,correlated
R2504	T3385	T3384	nmod	Figures,7
R2505	T3386	T3384	nummod	6,7
R2506	T3387	T3384	punct	", ",7
R2507	T3388	T3384	punct	),7
R2508	T3389	T3369	punct	", ",correlated
R2509	T3390	T3369	advcl	suggesting,correlated
R2510	T3391	T3392	mark	that,is
R2511	T3392	T3390	ccomp	is,suggesting
R2512	T3393	T3394	det	the,cluster
R2513	T3394	T3392	nsubj	cluster,is
R2514	T3395	T3394	amod	entire,cluster
R2515	T3396	T3394	compound	Tas2r,cluster
R2516	T3397	T3398	det	a,haplotype
R2517	T3398	T3392	attr	haplotype,is
R2518	T3399	T3398	amod	single,haplotype
R2519	T3400	T3401	dep	that,varies
R2520	T3401	T3398	relcl	varies,haplotype
R2521	T3402	T3401	prep	with,varies
R2522	T3403	T3404	compound	QHCl,taster
R2523	T3404	T3405	compound	taster,status
R2524	T3405	T3402	pobj	status,with
R2525	T3406	T3369	punct	.,correlated
R4727	T6332	T6333	compound	Lick,ratios
R4728	T6334	T6335	punct	(,SE
R4729	T6335	T6333	parataxis	SE,ratios
R4730	T6336	T6335	nmod	mean,SE
R4731	T6337	T6335	punct	±,SE
R4732	T6338	T6335	punct	),SE
R4733	T6339	T6333	prep	for,ratios
R4734	T6340	T6341	nmod	B6,strains
R4735	T6341	T6339	pobj	strains,for
R4736	T6342	T6340	punct	", ",B6
R4737	T6343	T6340	conj	D2,B6
R4738	T6344	T6343	cc	and,D2
R4739	T6345	T6343	conj	BXD,D2
R4740	T6346	T6333	punct	.,ratios
R4741	T6348	T6349	punct	(,A
R4742	T6349	T6350	meta	A,ratios
R4743	T6351	T6349	punct	),A
R4744	T6352	T6350	compound	Mean,ratios
R4745	T6353	T6350	compound	lick,ratios
R4746	T6354	T6350	prep	for,ratios
R4747	T6355	T6356	nmod	B6,mice
R4748	T6356	T6354	pobj	mice,for
R4749	T6357	T6358	punct	(,circles
R4750	T6358	T6355	parataxis	circles,B6
R4751	T6359	T6358	amod	filled,circles
R4752	T6360	T6358	punct	),circles
R4753	T6361	T6355	cc	and,B6
R4754	T6362	T6355	conj	D2,B6
R4755	T6363	T6364	punct	(,circles
R4756	T6364	T6362	parataxis	circles,D2
R4757	T6365	T6364	amod	open,circles
R4758	T6366	T6364	punct	),circles
R4759	T6367	T6350	prep	at,ratios
R4760	T6368	T6369	nummod	two,concentrations
R4761	T6369	T6367	pobj	concentrations,at
R4762	T6370	T6369	prep	of,concentrations
R4763	T6371	T6370	pobj	QHCl,of
R4764	T6372	T6371	cc	and,QHCl
R4765	T6373	T6371	conj	DB,QHCl
R4766	T6374	T6350	punct	.,ratios
R4767	T6376	T6377	prep	In,indicates
R4768	T6378	T6379	det	all,panels
R4769	T6379	T6376	pobj	panels,In
R4770	T6380	T6377	punct	", ",indicates
R4771	T6381	T6382	det	a,ratio
R4772	T6382	T6377	nsubj	ratio,indicates
R4773	T6383	T6382	amod	lower,ratio
R4774	T6384	T6382	compound	mean,ratio
R4775	T6385	T6382	compound	lick,ratio
R4776	T6386	T6387	det	a,aversion
R4777	T6387	T6377	dobj	aversion,indicates
R4778	T6388	T6387	amod	greater,aversion
R4779	T6389	T6387	punct	", ",aversion
R4780	T6390	T6387	cc	and,aversion
R4781	T6391	T6392	advmod	therefore,sensitivity
R4782	T6392	T6387	conj	sensitivity,aversion
R4783	T6393	T6392	amod	greater,sensitivity
R4784	T6394	T6392	compound	taste,sensitivity
R4785	T6395	T6387	punct	", ",aversion
R4786	T6396	T6387	prep	to,aversion
R4787	T6397	T6398	det	the,stimulus
R4788	T6398	T6396	pobj	stimulus,to
R4789	T6399	T6377	punct	.,indicates
R4790	T6401	T6402	prep	For,represented
R4791	T6403	T6404	compound	panels,B
R4792	T6404	T6401	pobj	B,For
R4793	T6405	T6404	punct	", ",B
R4794	T6406	T6404	conj	C,B
R4795	T6407	T6406	punct	", ",C
R4796	T6408	T6406	cc	and,C
R4797	T6409	T6406	conj	D,C
R4798	T6410	T6402	punct	", ",represented
R4799	T6411	T6412	det	each,strain
R4800	T6412	T6402	nsubjpass	strain,represented
R4801	T6413	T6412	compound	BXD,strain
R4802	T6414	T6402	auxpass	is,represented
R4803	T6415	T6402	agent	by,represented
R4804	T6416	T6417	det	a,color
R4805	T6417	T6415	pobj	color,by
R4806	T6418	T6417	amod	different,color
R4807	T6419	T6402	punct	", ",represented
R4808	T6420	T6402	cc	and,represented
R4809	T6421	T6402	conj	listed,represented
R4810	T6422	T6421	prep	in,listed
R4811	T6423	T6422	pobj	order,in
R4812	T6424	T6421	prep	from,listed
R4813	T6425	T6426	amod	least,sensitive
R4814	T6426	T6424	amod	sensitive,from
R4815	T6427	T6424	prep	to,from
R4816	T6428	T6429	advmod	most,sensitive
R4817	T6429	T6427	amod	sensitive,to
R4818	T6430	T6424	prep	to,from
R4819	T6431	T6432	nummod	1,mM
R4820	T6432	T6433	compound	mM,QHCL
R4821	T6433	T6430	pobj	QHCL,to
R4822	T6434	T6402	punct	.,represented
R4823	T6436	T6437	punct	(,B
R4824	T6437	T6438	meta	B,ratios
R4825	T6439	T6437	punct	),B
R4826	T6440	T6438	compound	Mean,ratios
R4827	T6441	T6438	compound	lick,ratios
R4828	T6442	T6438	prep	for,ratios
R4829	T6443	T6444	det	the,strains
R4830	T6444	T6442	pobj	strains,for
R4831	T6445	T6444	nummod	six,strains
R4832	T6446	T6444	compound	BXD,strains
R4833	T6447	T6448	dep	that,are
R4834	T6448	T6444	relcl	are,strains
R4835	T6449	T6450	advmod	most,sensitive
R4836	T6450	T6448	acomp	sensitive,are
R4837	T6451	T6450	prep	to,sensitive
R4838	T6452	T6451	pobj	QHCl,to
R4839	T6453	T6448	prep	in,are
R4840	T6454	T6455	det	this,assay
R4841	T6455	T6453	pobj	assay,in
R4842	T6456	T6438	punct	.,ratios
R4843	T6458	T6459	punct	(,C
R4844	T6459	T6460	meta	C,ratios
R4845	T6461	T6459	punct	),C
R4846	T6462	T6460	compound	Mean,ratios
R4847	T6463	T6460	compound	lick,ratios
R4848	T6464	T6460	prep	for,ratios
R4849	T6465	T6466	det	the,strains
R4850	T6466	T6464	pobj	strains,for
R4851	T6467	T6466	nummod	five,strains
R4852	T6468	T6466	compound	BXD,strains
R4853	T6469	T6470	dep	that,are
R4854	T6470	T6466	relcl	are,strains
R4855	T6471	T6472	advmod	least,sensitive
R4856	T6472	T6470	acomp	sensitive,are
R4857	T6473	T6472	prep	to,sensitive
R4858	T6474	T6473	pobj	QHCl,to
R4859	T6475	T6470	prep	in,are
R4860	T6476	T6477	det	this,assay
R4861	T6477	T6475	pobj	assay,in
R4862	T6478	T6460	punct	.,ratios
R4863	T6480	T6481	punct	(,D
R4864	T6481	T6482	meta	D,ratios
R4865	T6483	T6481	punct	),D
R4866	T6484	T6482	compound	Mean,ratios
R4867	T6485	T6482	compound	lick,ratios
R4868	T6486	T6482	prep	for,ratios
R4869	T6487	T6488	det	the,strains
R4870	T6488	T6486	pobj	strains,for
R4871	T6489	T6488	nummod	six,strains
R4872	T6490	T6488	compound	BXD,strains
R4873	T6491	T6488	amod	intermediate,strains
R4874	T6492	T6491	prep	in,intermediate
R4875	T6493	T6494	compound	QHCl,sensitivity
R4876	T6494	T6492	pobj	sensitivity,in
R4877	T6495	T6494	compound	taste,sensitivity
R4878	T6496	T6494	prep	to,sensitivity
R4879	T6497	T6496	pobj	those,to
R4880	T6498	T6497	prep	in,those
R4881	T6499	T6500	punct	(,B
R4882	T6500	T6498	pobj	B,in
R4883	T6501	T6500	punct	),B
R4884	T6502	T6500	cc	and,B
R4885	T6503	T6504	punct	(,C
R4886	T6504	T6500	conj	C,B
R4887	T6505	T6482	punct	),ratios
R4888	T6506	T6482	punct	.,ratios
R4889	T6508	T6509	nsubjpass	Cutoffs,set
R4890	T6509	T6518	ccomp	set,exhibited
R4891	T6510	T6508	prep	for,Cutoffs
R4892	T6511	T6512	det	the,groups
R4893	T6512	T6510	pobj	groups,for
R4894	T6513	T6512	nummod	three,groups
R4895	T6514	T6512	compound	QHCl,groups
R4896	T6515	T6512	compound	taster,groups
R4897	T6516	T6509	auxpass	were,set
R4898	T6517	T6509	advmod	arbitrarily,set
R4899	T6519	T6509	punct	", ",set
R4900	T6520	T6521	mark	as,was
R4901	T6521	T6509	advcl	was,set
R4902	T6522	T6521	expl	there,was
R4903	T6523	T6524	det	a,continuity
R4904	T6524	T6521	attr	continuity,was
R4905	T6525	T6524	prep	of,continuity
R4906	T6526	T6527	det	the,phenotype
R4907	T6527	T6525	pobj	phenotype,of
R4908	T6528	T6524	prep	at,continuity
R4909	T6529	T6530	nummod	1,mM
R4910	T6530	T6531	compound	mM,QHCl
R4911	T6531	T6528	pobj	QHCl,at
R4912	T6532	T6518	punct	: ,exhibited
R4913	T6533	T6534	amod	sensitive,strains
R4914	T6534	T6518	nsubj	strains,exhibited
R4915	T6535	T6536	det	a,ratio
R4916	T6536	T6518	dobj	ratio,exhibited
R4917	T6537	T6536	compound	lick,ratio
R4918	T6538	T6536	prep	for,ratio
R4919	T6539	T6540	nummod	1,mM
R4920	T6540	T6541	compound	mM,QHCl
R4921	T6541	T6538	pobj	QHCl,for
R4922	T6542	T6536	prep	of,ratio
R4923	T6543	T6544	punct	≤,0.3
R4924	T6544	T6542	pobj	0.3,of
R4925	T6545	T6518	punct	", ",exhibited
R4926	T6546	T6547	amod	intermediate,strains
R4927	T6547	T6548	nsubj	strains,0.6
R4928	T6548	T6518	conj	0.6,exhibited
R4929	T6549	T6548	quantmod	from,0.6
R4930	T6550	T6548	quantmod	0.31,0.6
R4931	T6551	T6548	punct	-,0.6
R4932	T6552	T6548	punct	", ",0.6
R4933	T6553	T6548	cc	and,0.6
R4934	T6554	T6555	amod	insensitive,strains
R4935	T6555	T6556	nsubj	strains,0.6
R4936	T6556	T6548	conj	0.6,0.6
R4937	T6557	T6556	punct	>,0.6
R4938	T6558	T6518	punct	.,exhibited
R4939	T6560	T6561	det	The,absence
R4940	T6561	T6562	nsubj	absence,suggests
R4941	T6563	T6561	prep	of,absence
R4942	T6564	T6565	nummod	two,classes
R4943	T6565	T6563	pobj	classes,of
R4944	T6566	T6565	amod	distinct,classes
R4945	T6567	T6565	amod	phenotypic,classes
R4946	T6568	T6569	mark	that,is
R4947	T6569	T6562	ccomp	is,suggests
R4948	T6570	T6569	nsubj	sensitivity,is
R4949	T6571	T6570	prep	to,sensitivity
R4950	T6572	T6571	pobj	QHCL,to
R4951	T6573	T6569	prep	under,is
R4952	T6574	T6575	amod	polygenic,control
R4953	T6575	T6573	pobj	control,under
R4954	T6576	T6562	punct	.,suggests
R1238	T1698	T1696	attr	difference,was
R1240	T1700	T1698	compound	strain,difference
R1241	T1701	T1696	prep	for,was
R1242	T1702	T1703	det	both,QHCl
R1243	T1703	T1701	pobj	QHCl,for
R1244	T1704	T1705	nummod	1,mM
R1245	T1705	T1703	compound	mM,QHCl
R1246	T1706	T1704	cc	and,1
R1247	T1707	T1704	conj	3,1
R1248	T1708	T1709	punct	(,0.0001
R1249	T1709	T1703	parataxis	0.0001,QHCl
R1250	T1710	T1711	nmod	F,25
R1251	T1711	T1715	nsubj	25,24.6
R1252	T1712	T1711	punct	[,25
R1253	T1713	T1711	nummod	1,25
R1254	T1714	T1711	punct	",",25
R1255	T1715	T1709	ccomp	24.6,0.0001
R1256	T1716	T1711	punct	],25
R1302	T1769	T1770	nsubj	We,tested
R1303	T1771	T1770	advmod	next,tested
R1304	T1772	T1770	dobj	mice,tested
R1305	T1773	T1772	prep	from,mice
R1306	T1774	T1775	nummod	17,lines
R1307	T1775	T1773	pobj	lines,from
R1308	T1776	T1775	compound	BXD,lines
R1309	T1777	T1770	prep	in,tested
R1310	T1778	T1779	det	the,manner
R1311	T1779	T1777	pobj	manner,in
R1312	T1780	T1779	amod	same,manner
R1313	T1781	T1770	punct	.,tested
R1314	T1783	T1784	compound	BXD,mice
R1315	T1784	T1785	nsubj	mice,avoided
R1316	T1786	T1785	advmod	also,avoided
R1317	T1787	T1785	advmod	typically,avoided
R1318	T1788	T1789	det	both,stimuli
R1319	T1789	T1785	dobj	stimuli,avoided
R1320	T1790	T1785	prep	in,avoided
R1321	T1791	T1792	det	a,manner
R1322	T1792	T1790	pobj	manner,in
R1323	T1793	T1794	npadvmod	concentration,dependent
R1324	T1794	T1792	amod	dependent,manner
R1325	T1795	T1796	punct	(,Table
R1326	T1796	T1785	parataxis	Table,avoided
R1327	T1797	T1798	nmod	Figures,1B
R1328	T1798	T1796	dep	1B,Table
R1329	T1799	T1800	punct	–,1D
R1330	T1800	T1798	prep	1D,1B
R1331	T1801	T1796	punct	;,Table
R1332	T1802	T1796	nummod	1,Table
R1509	T2091	T2089	punct	),Figure
R1510	T2092	T2034	punct	.,were
R1511	T2100	T2099	nummod	6,hromosome
R1512	T2112	T2111	prep	to,ked
R2249	T3108	T3117	advcl	found,are
R2254	T3113	T3111	pobj	Tas2rs,between
R2257	T3116	T3108	auxpass	are,found
R2258	T3118	T3108	prep	in,found
R2259	T3119	T3120	det	all,regions
R2260	T3120	T3118	pobj	regions,in
R2261	T3121	T3120	prep	of,regions
R2262	T3122	T3123	det	the,receptors
R2263	T3123	T3121	pobj	receptors,of
R2264	T3124	T3117	punct	", ",are
R2265	T3125	T3126	nummod	23,%
R2266	T3126	T3117	nsubj	%,are
R2267	T3127	T3126	prep	of,%
R2268	T3128	T3129	det	the,changes
R2269	T3129	T3127	pobj	changes,of
R2270	T3130	T3131	compound	amino,acid
R2271	T3131	T3129	compound	acid,changes
R2272	T3132	T3129	acl	seen,changes
R2273	T3133	T3117	prep	within,are
R2274	T3134	T3135	det	the,loops
R2275	T3135	T3133	pobj	loops,within
R2276	T3136	T3135	amod	first,loops
R2277	T3137	T3135	nummod	two,loops
R2278	T3138	T3135	amod	extracellular,loops
R2279	T3139	T3135	prep	of,loops
R2280	T3140	T3141	det	the,T2Rs
R2281	T3141	T3139	pobj	T2Rs,of
R2282	T3142	T3143	punct	(,shown
R2283	T3143	T3117	parataxis	shown,are
R2284	T3144	T3143	nsubj	data,shown
R2285	T3145	T3143	neg	not,shown
R2286	T3146	T3143	punct	),shown
R2287	T3147	T3117	punct	.,are
R2288	T3154	T3155	nsubj	variability,suggested
R2289	T3156	T3154	prep	between,variability
R2290	T3157	T3158	amod	orthologous,receptors
R2291	T3158	T3156	pobj	receptors,between
R2292	T3159	T3154	prep	in,variability
R2293	T3160	T3161	det	these,strains
R2294	T3161	T3159	pobj	strains,in
R2295	T3162	T3161	nummod	two,strains
R2296	T3163	T3161	amod	inbred,strains
R2297	T3164	T3165	mark	that,be
R2298	T3165	T3155	ccomp	be,suggested
R2299	T3166	T3165	nsubj	it,be
R2300	T3167	T3165	aux	might,be
R2301	T3168	T3165	acomp	possible,be
R2302	T3169	T3170	aux	to,narrow
R2303	T3170	T3165	xcomp	narrow,be
R2304	T3171	T3172	det	the,boundaries
R2305	T3172	T3170	dobj	boundaries,narrow
R2306	T3173	T3172	amod	physical,boundaries
R2307	T3174	T3172	prep	of,boundaries
R2308	T3175	T3176	det	the,QTL
R2309	T3176	T3174	pobj	QTL,of
R2310	T3177	T3178	compound	QHCl,taste
R2311	T3178	T3176	compound	taste,QTL
R2312	T3179	T3170	prep	by,narrow
R2313	T3180	T3179	pcomp	determining,by
R2314	T3181	T3182	det	which,alleles
R2315	T3182	T3184	dep	alleles,correlated
R2316	T3183	T3182	compound	Tas2r,alleles
R2317	T3184	T3180	ccomp	correlated,determining
R2318	T3185	T3184	auxpass	are,correlated
R2319	T3186	T3184	prep	with,correlated
R2320	T3187	T3188	compound	QHCl,taste
R2321	T3188	T3189	compound	taste,sensitivity
R2322	T3189	T3186	pobj	sensitivity,with
R2323	T3190	T3155	punct	.,suggested
R2324	T3192	T3193	advmod	Therefore,proceeded
R2325	T3194	T3193	punct	", ",proceeded

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id	Subject	Object	Predicate	Lexical cue
T7206	13308-13317	SO_EXT:0001024	denotes	haplotype
T7205	13302-13307	PR_EXT:000036337	denotes	Tas2r
T7204	13206-13215	SO_EXT:0001024	denotes	haplotype
T7203	13200-13205	PR_EXT:000036337	denotes	Tas2r
T7202	13152-13157	GO:0050909	denotes	taste
T7201	13106-13110	NCBITaxon:10088	denotes	mice
T7200	13022-13026	NCBITaxon:10088	denotes	mice
T7199	13001-13010	SO_EXT:0001024	denotes	haplotype
T7198	12980-12989	SO_EXT:0001024	denotes	haplotype
T7197	12966-12975	SO_EXT:0001024	denotes	haplotype
T7196	12960-12965	PR_EXT:000036337	denotes	Tas2r
T7195	12858-12863	GO:0050909	denotes	taste
T7194	12828-12836	SO_EXT:genotype_or_entity_with_genotype	denotes	genotype
T7193	12822-12827	PR_EXT:000036337	denotes	Tas2r
T7094	12759-12771	GO_PATO_EXT:biological_behavior	denotes	behaviorally
T7093	12713-12719	SO_EXT:0001023	denotes	allele
T7092	12695-12701	SO_EXT:0001023	denotes	allele
T7091	12612-12617	PR_EXT:000036337	denotes	Tas2r
T7090	12576-12579	CHEBI_SO_EXT:DNA	denotes	DNA
T7089	12568-12579	SO_EXT:genomic_DNA	denotes	genomic DNA
T7088	12533-12543	GO_SO_EXT:chromosome	denotes	chromosome
T7087	12512-12518	PR_EXT:000036337	denotes	Tas2rs
T7086	12486-12497	SO_EXT:0000195	denotes	coding exon
T7085	12476-12480	NCBITaxon:10088	denotes	mice
T7084	12453-12462	SO_EXT:0001024	denotes	haplotype
T7083	12427-12432	PR_EXT:000036337	denotes	Tas2r
T6865	8229-8235	SO_EXT:0001026	denotes	genome
T6864	8210-8218	SO_EXT:sequence_assembly_entity_or_process	denotes	assembly
T6863	8183-8192	GO_SO_EXT:chromosomal_part_or_position_or_region_or_site	denotes	positions
T6862	8170-8180	_FRAGMENT	denotes	chromosome
T6861	8157-8158	CHEBI_SO_EXT:base	denotes	b
T6860	8126-8130	PR_EXT:000013555	denotes	Prh1
T6859	8117-8121	PR_EXT:000013555	denotes	Prp2
T6858	8107-8115	CHEBI_PR_EXT:protein	denotes	proteins
T6857	8098-8106	UBERON:0001836	denotes	salivary
T6856	8085-8092	CHEBI_SO_EXT:proline	denotes	proline
T6855	8076-8084	SO_EXT:sequence_coding_function	denotes	encoding
T6854	8070-8075	SO_EXT:0000704	denotes	genes
T6853	8041-8047	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	marker
T6852	8029-8040	SO_EXT:polymorphism	denotes	polymorphic
T6851	7971-7977	PR_EXT:000036337	denotes	Tas2rs
T6850	7945-7955	GO_SO_EXT:chromosome	denotes	chromosome
T6849	7925-7930	SO_EXT:0000704	denotes	genes
T6848	7919-7924	PR_EXT:000036337	denotes	Tas2r
T6847	7885-7890	PR_EXT:000036337	denotes	Tas2r
T6846	7872-7882	GO_SO_EXT:chromosome	denotes	chromosome
T6699	7782-7788	SO_EXT:0001026	denotes	genome
T6698	7776-7781	NCBITaxon:10088	denotes	mouse
T6697	7726-7727	CHEBI_SO_EXT:base	denotes	b
T6696	7704-7711	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	markers
T6695	7692-7703	SO_EXT:polymorphism	denotes	polymorphic
T6694	7647-7653	PR_EXT:000036337	denotes	Tas2rs
T6693	7614-7635	GO_EXT:0033038	denotes	bitter taste receptor
T6692	7614-7626	GO:0050913	denotes	bitter taste
T6691	7552-7559	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	markers
T6690	7519-7522	SO_EXT:0000771	denotes	QTL
T6689	7480-7486	SO_EXT:0001026	denotes	genome
T6688	7431-7437	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	marker
T6687	7419-7430	SO_EXT:polymorphism	denotes	polymorphic
T6686	7311-7321	GO_SO_EXT:chromosome	denotes	chromosome
T6685	7260-7270	GO_SO_EXT:chromosome	denotes	chromosome
T6684	7250-7256	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	marker
T6683	7224-7227	SO_EXT:0000771	denotes	QTL
T6596	5304-5310	SO_EXT:0001026	denotes	genome
T6595	5248-5251	SO_EXT:0000771	denotes	QTL
T6594	5189-5198	GO_EXT:reaction_or_response	denotes	responses
T6593	5183-5188	GO:0050909	denotes	taste
T6592	5151-5161	GO_SO_EXT:chromosome	denotes	chromosome
T6591	5144-5147	SO_EXT:0000771	denotes	QTL
T6590	5106-5116	GO_SO_EXT:chromosome	denotes	chromosome
T6589	5099-5102	SO_EXT:0000771	denotes	QTL
T6588	5022-5032	GO_SO_EXT:chromosome	denotes	chromosome
T6587	5016-5021	NCBITaxon:10088	denotes	mouse
T6977	11026-11042	CHEBI_SO_EXT:oligonucleotide	denotes	oligonucleotides
T6976	11014-11021	CHEBI_GO_SO_EXT:enzyme	denotes	enzymes
T6975	11002-11021	GO_EXT:0015666	denotes	restriction enzymes
T6974	10948-10954	GO_EXT:taster	denotes	taster
T6973	10921-10927	GO_EXT:taster	denotes	taster
T6972	10893-10899	GO_EXT:taster	denotes	taster
T6971	10852-10860	SO_EXT:genotype_or_entity_with_genotype	denotes	genotype
T6970	10846-10851	PR_EXT:000036337	denotes	Tas2r
T6969	10797-10805	PR_EXT:000016902	denotes	Tas2r120
T6968	10784-10795	SO_EXT:0000006	denotes	PCR product
T6967	10726-10734	PR_EXT:000016899	denotes	Tas2r116
T6966	10716-10724	PR_EXT:000016892	denotes	Tas2r105
T6965	10702-10714	SO_EXT:0000006	denotes	PCR products
T6964	10620-10626	PR_EXT:000036337	denotes	Tas2rs
T6963	10604-10611	SO_EXT:0001023	denotes	alleles
T6962	10586-10592	PR_EXT:000036337	denotes	Tas2rs
T6961	10552-10561	SO_EXT:sequence_variation_entity_or_quality	denotes	variation
T6960	10544-10551	SO_EXT:0001023	denotes	Allelic
T6586	5007-5012	GO:0050909	denotes	taste
T6585	4994-4997	SO_EXT:0000771	denotes	QTL
T6331	3998-4005	GO:0065007	denotes	control
T6330	3992-3997	SO_EXT:0000704	denotes	genic
T6329	3673-3679	GO_EXT:taster	denotes	taster
T6328	3603-3608	GO:0050909	denotes	taste
T6327	3165-3170	GO:0050909	denotes	taste
T6326	3031-3035	NCBITaxon:10088	denotes	mice
T2699	12398-12404	GO_EXT:taster	denotes	taster
T2698	12366-12375	SO_EXT:0001024	denotes	haplotype
T2697	12340-12345	PR_EXT:000036337	denotes	Tas2r
T2696	12281-12286	GO:0050909	denotes	taste
T2695	12244-12248	SO_EXT:0000704	denotes	gene
T2694	12238-12243	PR_EXT:000036337	denotes	Tas2r
T2693	12221-12229	SO_EXT:genotype_or_entity_with_genotype	denotes	genotype
T2692	12112-12117	PR_EXT:000036337	denotes	Tas2r
T2691	12017-12027	GO_SO_EXT:chromosome	denotes	chromosome
T2690	11978-11991	GO_SO_EXT:sequence_rearrangement_process	denotes	recombination
T2689	11911-11915	SO_EXT:0000704	denotes	gene
T2688	11893-11901	SO_EXT:genotype_or_entity_with_genotype	denotes	genotype
T2687	11856-11867	SO_EXT:0000006	denotes	PCR product
T2686	11833-11837	NCBITaxon:10088	denotes	mice
T2685	11819-11826	SO_EXT:sequence_deletion_process	denotes	deleted
T2684	11793-11801	PR_EXT:000016902	denotes	Tas2r120
T2683	11743-11767	GO_EXT:0015666	denotes	restriction endonuclease
T2682	11713-11721	PR_EXT:000016896	denotes	Tas2r110
T2681	11700-11708	PR_EXT:000016898	denotes	Tas2r114
T2680	11690-11698	PR_EXT:000016891	denotes	Tas2r104
T2679	11683-11688	SO_EXT:0000704	denotes	genes
T2660	10489-10497	CL_GO_EXT:cell	denotes	cellular
T2659	10484-10497	GO:0005576	denotes	extracellular
T2658	10446-10453	SO_EXT:sequence_alteration_entity_or_process	denotes	changes
T2657	10435-10445	CHEBI_SO_EXT:amino_acid	denotes	amino acid
T2656	10413-10422	GO_EXT:0004872	denotes	receptors
T2655	10374-10380	PR_EXT:000036337	denotes	Tas2rs
T2654	10347-10355	CHEBI_EXT:residue	denotes	residues
T2653	10335-10346	SO_EXT:polymorphism	denotes	polymorphic
T2652	10295-10307	SO_EXT:0000195	denotes	coding exons
T2651	10251-10261	CHEBI_SO_EXT:nucleotide	denotes	nucleotide
T2650	10244-10275	SO_EXT:0000694	denotes	single nucleotide polymorphisms
T2649	10230-10234	NCBITaxon:10088	denotes	mice
T2648	10209-10216	SO_EXT:0001023	denotes	alleles
T2647	10178-10184	PR_EXT:000036337	denotes	Tas2rs
T2646	10160-10169	SO_EXT:sequence_alteration_entity_or_process	denotes	mutations
T2645	10151-10159	SO_EXT:missense_quality_or_entity	denotes	missense
T2644	10115-10121	PR_EXT:000036337	denotes	Tas2rs
T2643	10070-10081	SO_EXT:0000336	denotes	pseudogenes
T2642	10057-10062	SO_EXT:0000704	denotes	genes
T2641	10007-10019	GO_SO_EXT:frameshift_entity_or_process	denotes	frame shifts
T2640	9985-9994	SO_EXT:sequence_deletion_entity_or_process	denotes	deletions
T2639	9965-9974	SO_EXT:sequence_alteration_entity_or_process	denotes	mutations
T2638	9956-9964	SO_EXT:missense_quality_or_entity	denotes	missense
T2637	9927-9935	PR_EXT:000016900	denotes	Tas2r117
T2636	9914-9922	PR_EXT:000016890	denotes	Tas2r103
T2635	9905-9912	SO_EXT:0001023	denotes	alleles
T2634	9892-9896	NCBITaxon:10088	denotes	mice
T2633	9878-9885	SO_EXT:sequence_deletion_process	denotes	deleted
T2632	9869-9874	PR_EXT:000036337	denotes	Tas2r
T2631	9810-9826	CHEBI_SO_EXT:oligonucleotide	denotes	oligonucleotides
T2630	9766-9769	CHEBI_SO_EXT:DNA	denotes	DNA
T2629	9758-9769	SO_EXT:genomic_DNA	denotes	genomic DNA
T2628	9717-9725	PR_EXT:000016902	denotes	Tas2r120
T2627	9673-9683	CHEBI_SO_EXT:amino_acid	denotes	amino acid
T2626	9626-9634	PR_EXT:000016904	denotes	Tas2r124
T2625	9613-9621	PR_EXT:000016893	denotes	Tas2r106
T2624	9595-9602	SO_EXT:0001023	denotes	alleles
T2623	9589-9594	PR_EXT:000036337	denotes	Tas2r
T2622	9535-9546	SO_EXT:0000855	denotes	orthologues
T2621	9512-9521	SO_EXT:biological_sequence	denotes	sequences
T2620	9470-9477	SO_EXT:0000440	denotes	vectors
T2619	9462-9469	SO_EXT:sequence_cloning_process	denotes	cloning
T2618	9429-9441	SO_EXT:0000006	denotes	PCR products
T2617	9424-9427	CHEBI_SO_EXT:DNA	denotes	DNA
T2616	9416-9427	SO_EXT:genomic_DNA	denotes	genomic DNA
T2615	9392-9407	SO_EXT:coding_sequence	denotes	coding sequence
T2614	9386-9391	PR_EXT:000036337	denotes	Tas2r
T2613	9360-9366	CHEBI_SO_EXT:oligonucleotide	denotes	oligos
T2612	9317-9322	PR_EXT:000036337	denotes	Tas2r
T2611	9286-9301	SO_EXT:coding_sequence	denotes	coding sequence
T2610	9273-9281	SO:0000357	denotes	flanking
T2609	9258-9264	SO_EXT:sequence_coding_function	denotes	coding
T2608	9234-9250	CHEBI_SO_EXT:oligonucleotide	denotes	oligonucleotides
T2606	9173-9183	GO_SO_EXT:chromosome	denotes	chromosome
T2605	9125-9136	SO_EXT:0000336	denotes	pseudogenes
T2604	9119-9124	PR_EXT:000036337	denotes	Tas2r
T2603	9085-9091	PR_EXT:000036337	denotes	Tas2rs
T2602	9035-9040	GO:0050909	denotes	taste
T2601	8999-9004	PR_EXT:000036337	denotes	Tas2r
T2600	8968-8983	SO_EXT:coding_sequence	denotes	coding sequence
T2599	8948-8956	SO_EXT:sequence_alteration_entity_or_process	denotes	mutation
T2598	8936-8944	SO_EXT:sequence_deletion_entity_or_process	denotes	deletion
T2597	8808-8815	CHEBI_PR_EXT:protein	denotes	protein
T2596	8790-8800	GO:0010467	denotes	expression
T2595	8775-8781	SO_EXT:0001023	denotes	allele
T2594	8769-8774	PR_EXT:000036337	denotes	Tas2r
T2593	8742-8760	SO_EXT:0005836	denotes	regulatory regions
T2592	8742-8752	GO:0065007	denotes	regulatory
T2591	8732-8738	SO_EXT:sequence_coding_function	denotes	coding
T2590	8716-8725	SO_EXT:sequence_alteration_entity_or_process	denotes	Mutations
T2589	8692-8710	GO_EXT:cell_communication_or_signaling_or_signal_transduction	denotes	signaling cascades
T2588	8660-8668	GO_EXT:0004872	denotes	receptor
T2587	8649-8656	CHEMINF_GO_EXT:chemical_binding_or_bond_formation	denotes	binding
T2586	8642-8648	CHEBI_GO_EXT:ligand	denotes	ligand
T2585	8616-8623	CHEBI_PR_EXT:protein	denotes	protein
T2584	8602-8608	SO_EXT:0001023	denotes	allele
T2583	8596-8601	PR_EXT:000036337	denotes	Tas2r
T2582	8576-8587	SO_EXT:0000195	denotes	coding exon
T2581	8552-8561	SO_EXT:sequence_alteration_entity_or_process	denotes	mutations
T2580	8543-8551	SO_EXT:missense_quality_or_entity	denotes	Missense
T2579	8533-8537	NCBITaxon:10088	denotes	mice
T2578	8469-8476	SO_EXT:sequence_deletion_process	denotes	deleted
T2577	8451-8461	SO_EXT:0000336	denotes	pseudogene
T2576	8439-8445	SO_EXT:0001023	denotes	allele
T2575	8433-8438	PR_EXT:000036337	denotes	Tas2r
T2574	8370-8375	SO_EXT:0000704	denotes	genes
T2573	8364-8369	PR_EXT:000036337	denotes	Tas2r
T2572	8323-8326	SO_EXT:0000771	denotes	QTL
T2571	8305-8310	GO:0050909	denotes	taste
T2570	8287-8297	GO_SO_EXT:chromosome	denotes	chromosome
T2569	8267-8273	PR_EXT:000036337	denotes	Tas2rs
T2568	8242-8249	SO_EXT:0001023	denotes	alleles
T2567	8238-8241	PR_EXT:000036337	denotes	T2R
T1945	7200-7203	SO_EXT:0000771	denotes	QTL
T1944	7182-7187	GO:0050909	denotes	taste
T1943	7125-7131	PR_EXT:000036337	denotes	Tas2rs
T1942	7071-7080	CHEBI:36357	denotes	compounds
T1941	7056-7070	GO:0050913	denotes	bitter-tasting
T1940	7000-7005	CL_GO_EXT:cell	denotes	cells
T1939	6985-7005	CL:0000209	denotes	taste receptor cells
T1938	6985-6999	GO_EXT:0008527	denotes	taste receptor
T1937	6985-6990	GO:0050909	denotes	taste
T1936	6971-6981	GO:0010467	denotes	expression
T1935	6944-6950	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	marker
T1934	6844-6845	CHEBI_SO_EXT:base	denotes	b
T1933	6804-6808	PR_EXT:000036337	denotes	T2Rs
T1932	6793-6799	SO_EXT:sequence_coding_function	denotes	encode
T1931	6780-6785	SO_EXT:0000704	denotes	genes
T1930	6774-6779	PR_EXT:000036337	denotes	Tas2r
T1929	6753-6768	GO_EXT:0008527	denotes	taste receptors
T1928	6753-6758	GO:0050909	denotes	taste
T1927	6744-6768	PR_EXT:000036337	denotes	T2R-type taste receptors
T1926	6729-6738	GO_EXT:0004872	denotes	receptors
T1925	6712-6716	CL_GO_EXT:cell	denotes	cell
T1924	6697-6716	CL:0000623	denotes	natural killer cell
T1923	6678-6686	GO_EXT:0004872	denotes	receptor
T1922	6650-6656	SO_EXT:sequence_coding_function	denotes	encode
T1921	6619-6624	SO_EXT:0000704	denotes	genes
T1920	6566-6567	CHEBI_SO_EXT:base	denotes	b
T1919	6544-6547	SO_EXT:0000771	denotes	QTL
T1918	6531-6541	GO_SO_EXT:chromosome	denotes	chromosome
T1917	6492-6498	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	marker
T1916	6469-6475	SO_EXT:0001026	denotes	genome
T1915	6369-6376	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	markers
T1914	6323-6329	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	marker
T1913	6285-6301	SO_EXT:physical_mapping_process	denotes	Physical mapping
T1912	6151-6156	NCBITaxon:10088	denotes	mouse
T1911	6157-6167	GO_SO_EXT:chromosomal_part_or_position_or_region_or_site	denotes	chromosome
T1910	6140-6150	_FRAGMENT	denotes	portion of
T1909	6089-6092	SO_EXT:0000771	denotes	QTL
T1908	6068-6071	SO_EXT:0000771	denotes	QTL
T1907	5990-5998	SO_EXT:genotype_or_entity_with_genotype	denotes	genotype
T1906	5954-5962	SO_EXT:genotype_or_entity_with_genotype	denotes	genotype
T1905	5929-5934	GO:0050909	denotes	taste
T1904	5886-5890	NCBITaxon:10088	denotes	mice
T1903	5808-5817	SO_EXT:genotype_or_entity_with_genotype	denotes	genotypes
T1902	5730-5736	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	marker
T1901	5571-5584	GO_SO_EXT:sequence_rearrangement_process	denotes	recombination
T1900	5502-5508	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	marker
T1899	5484-5487	SO_EXT:0000771	denotes	QTL
T1898	5429-5436	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	markers
T1897	5374-5380	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	marker
T1896	5353-5354	GO:0050909	denotes	s
T1895	5347-5350	SO_EXT:0000771	denotes	QTL
T1894	5335-5344	GO_SO_EXT:chromosome	denotes	hromosome
T1893	5331-5333	GO_SO_EXT:chromosome	denotes	he
T1892	5330-5331	SO_EXT:0000771	denotes	T
T1891	4938-4944	SO_EXT:0001026	denotes	genome
T1890	4887-4890	SO_EXT:0000771	denotes	QTL
T1889	4833-4843	GO_SO_EXT:chromosome	denotes	chromosome
T1888	4826-4829	SO_EXT:0000771	denotes	QTL
T1887	4804-4810	SO_EXT:0001026	denotes	genome
T1886	4751-4761	GO_SO_EXT:chromosome	denotes	chromosome
T1885	4701-4704	SO_EXT:0000771	denotes	QTL
T1884	4679-4685	SO_EXT:0001026	denotes	genome
T1883	4606-4612	SO_EXT:0001026	denotes	genome
T1882	4553-4564	GO_SO_EXT:chromosome	denotes	chromosomes
T1881	4542-4549	CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag	denotes	markers
T1880	4488-4493	GO:0050909	denotes	taste
T1521	4193-4198	GO:0050909	denotes	taste
T1520	4069-4073	NCBITaxon:10088	denotes	mice
T1519	4022-4026	NCBITaxon:10088	denotes	mice
T1500	9-14	GO:0050909	denotes	Taste
T1501	47-50	SO_EXT:0000771	denotes	QTL
T1502	55-67	GO:0050913	denotes	bitter taste
T1503	82-93	GO:0007631	denotes	consumption
T1504	152-161	GO:0007631	denotes	ingestive
T1505	307-311	NCBITaxon:10088	denotes	mice
T1506	335-340	GO:0050909	denotes	taste
T1507	360-365	GO:0050909	denotes	taste
T1508	423-427	NCBITaxon:10088	denotes	mice
T1509	525-531	CHEBI_GO_EXT:ligand	denotes	ligand
T1510	556-564	CHEBI:36357	denotes	compound
T1511	618-623	GO:0050909	denotes	taste
T1512	739-743	PATO_UBERON_EXT:male_or_bearer_of_maleness	denotes	male
T1513	748-754	PATO_UBERON_EXT:female_or_bearer_of_femaleness	denotes	female
T1514	765-769	NCBITaxon:10088	denotes	mice
T1515	868-877	CHEBI:36357	denotes	compounds
T1516	1000-1004	NCBITaxon:10088	denotes	mice
T1517	1049-1053	NCBITaxon:10088	denotes	mice
T1518	1141-1146	GO:0050909	denotes	taste
T2607	9200-9204	NCBITaxon:10088	denotes	mice
T7343	1268-1272	NCBITaxon:10088	denotes	mice
T1879	4460-4464	SO_EXT:0000771	denotes	QTLs
T1878	4360-4363	SO_EXT:0000771	denotes	QTL
T2678	11650-11656	SO_EXT:0001023	denotes	allele
T2677	11608-11619	SO_EXT:0000006	denotes	PCR product
T2676	11602-11607	PR_EXT:000036337	denotes	Tas2r
T2675	11508-11532	GO_EXT:0015666	denotes	restriction endonuclease
T2674	11433-11440	SO_EXT:0001023	denotes	alleles
T2673	11427-11432	PR_EXT:000036337	denotes	Tas2r
T2672	11404-11409	GO:0050909	denotes	taste
T2671	11331-11334	CHEBI_SO_EXT:DNA	denotes	DNA
T2670	11323-11334	SO_EXT:genomic_DNA	denotes	genomic DNA
T2669	11270-11275	GO:0050909	denotes	taste
T2668	11237-11244	SO_EXT:0001023	denotes	alleles
T2667	11231-11236	PR_EXT:000036337	denotes	Tas2r
T2666	11206-11209	SO_EXT:0000771	denotes	QTL
T2665	11200-11205	GO:0050909	denotes	taste
T2664	11080-11089	GO_EXT:0004872	denotes	receptors
T2663	11068-11079	SO:0000858	denotes	orthologous
T2662	11044-11045	PR_EXT:000036337	denotes	T
T2661	10511-10515	PR_EXT:000036337	denotes	T2Rs
R5153	T6863	T6862	_lexicallyChainedTo	positions,chromosome
R1370	T1911	T1910	_lexicallyChainedTo	chromosome,portion of

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id	Subject	Object	Predicate	Lexical cue
T7192	13308-13317	SO:0001024	denotes	haplotype
T7191	13302-13307	PR:000036337	denotes	Tas2r
T7190	13206-13215	SO:0001024	denotes	haplotype
T7189	13200-13205	PR:000036337	denotes	Tas2r
T7188	13152-13157	GO:0050909	denotes	taste
T7187	13106-13110	NCBITaxon:10088	denotes	mice
T7186	13022-13026	NCBITaxon:10088	denotes	mice
T7185	13001-13010	SO:0001024	denotes	haplotype
T7184	12980-12989	SO:0001024	denotes	haplotype
T7183	12966-12975	SO:0001024	denotes	haplotype
T7182	12960-12965	PR:000036337	denotes	Tas2r
T7181	12858-12863	GO:0050909	denotes	taste
T7180	12822-12827	PR:000036337	denotes	Tas2r
T7082	12713-12719	SO:0001023	denotes	allele
T7081	12695-12701	SO:0001023	denotes	allele
T7080	12612-12617	PR:000036337	denotes	Tas2r
T7079	12568-12575	SO:0001026	denotes	genomic
T7078	12512-12518	PR:000036337	denotes	Tas2rs
T7077	12486-12497	SO:0000195	denotes	coding exon
T7076	12476-12480	NCBITaxon:10088	denotes	mice
T7075	12453-12462	SO:0001024	denotes	haplotype
T7074	12427-12432	PR:000036337	denotes	Tas2r
T6955	10716-10724	PR:000016892	denotes	Tas2r105
T6954	10702-10714	SO:0000006	denotes	PCR products
T6953	10620-10626	PR:000036337	denotes	Tas2rs
T6952	10604-10611	SO:0001023	denotes	alleles
T6951	10586-10592	PR:000036337	denotes	Tas2rs
T6950	10544-10551	SO:0001023	denotes	Allelic
T6845	8229-8235	SO:0001026	denotes	genome
T6844	8126-8130	PR:000013555	denotes	Prh1
T6843	8117-8121	PR:000013555	denotes	Prp2
T6842	8098-8106	UBERON:0001836	denotes	salivary
T6841	8070-8075	SO:0000704	denotes	genes
T6840	7971-7977	PR:000036337	denotes	Tas2rs
T6839	7925-7930	SO:0000704	denotes	genes
T6838	7919-7924	PR:000036337	denotes	Tas2r
T6837	7885-7890	PR:000036337	denotes	Tas2r
T6682	7782-7788	SO:0001026	denotes	genome
T6681	7776-7781	NCBITaxon:10088	denotes	mouse
T6680	7647-7653	PR:000036337	denotes	Tas2rs
T6679	7614-7626	GO:0050913	denotes	bitter taste
T6678	7519-7522	SO:0000771	denotes	QTL
T6677	7480-7486	SO:0001026	denotes	genome
T6676	7224-7227	SO:0000771	denotes	QTL
T6959	10846-10851	PR:000036337	denotes	Tas2r
T6958	10797-10805	PR:000016902	denotes	Tas2r120
T6957	10784-10795	SO:0000006	denotes	PCR product
T6956	10726-10734	PR:000016899	denotes	Tas2r116
T6584	5304-5310	SO:0001026	denotes	genome
T6583	5248-5251	SO:0000771	denotes	QTL
T6582	5183-5188	GO:0050909	denotes	taste
T6581	5144-5147	SO:0000771	denotes	QTL
T6580	5099-5102	SO:0000771	denotes	QTL
T6579	5016-5021	NCBITaxon:10088	denotes	mouse
T6578	5007-5012	GO:0050909	denotes	taste
T6577	4994-4997	SO:0000771	denotes	QTL
T6325	3998-4005	GO:0065007	denotes	control
T6324	3992-3997	SO:0000704	denotes	genic
T6323	3603-3608	GO:0050909	denotes	taste
T6322	3165-3170	GO:0050909	denotes	taste
T6321	3031-3035	NCBITaxon:10088	denotes	mice
T2566	12366-12375	SO:0001024	denotes	haplotype
T2565	12340-12345	PR:000036337	denotes	Tas2r
T2564	12281-12286	GO:0050909	denotes	taste
T2563	12244-12248	SO:0000704	denotes	gene
T2562	12238-12243	PR:000036337	denotes	Tas2r
T2561	12112-12117	PR:000036337	denotes	Tas2r
T2560	11911-11915	SO:0000704	denotes	gene
T2559	11856-11867	SO:0000006	denotes	PCR product
T2558	11833-11837	NCBITaxon:10088	denotes	mice
T2557	11793-11801	PR:000016902	denotes	Tas2r120
T2556	11713-11721	PR:000016896	denotes	Tas2r110
T2555	11700-11708	PR:000016898	denotes	Tas2r114
T2554	11690-11698	PR:000016891	denotes	Tas2r104
T2553	11683-11688	SO:0000704	denotes	genes
T2552	11650-11656	SO:0001023	denotes	allele
T2551	11608-11619	SO:0000006	denotes	PCR product
T2550	11602-11607	PR:000036337	denotes	Tas2r
T2549	11433-11440	SO:0001023	denotes	alleles
T2548	11427-11432	PR:000036337	denotes	Tas2r
T2547	11404-11409	GO:0050909	denotes	taste
T2546	11323-11330	SO:0001026	denotes	genomic
T2545	11270-11275	GO:0050909	denotes	taste
T2544	11237-11244	SO:0001023	denotes	alleles
T2543	11231-11236	PR:000036337	denotes	Tas2r
T2542	11206-11209	SO:0000771	denotes	QTL
T2541	11200-11205	GO:0050909	denotes	taste
T2540	11068-11079	SO:0000858	denotes	orthologous
T2539	11044-11045	PR:000036337	denotes	T
T2538	10511-10515	PR:000036337	denotes	T2Rs
T2537	10484-10497	GO:0005576	denotes	extracellular
T2536	10374-10380	PR:000036337	denotes	Tas2rs
T2535	10295-10307	SO:0000195	denotes	coding exons
T2534	10244-10275	SO:0000694	denotes	single nucleotide polymorphisms
T2533	10230-10234	NCBITaxon:10088	denotes	mice
T2532	10209-10216	SO:0001023	denotes	alleles
T2531	10178-10184	PR:000036337	denotes	Tas2rs
T2530	10115-10121	PR:000036337	denotes	Tas2rs
T1877	7200-7203	SO:0000771	denotes	QTL
T1876	7182-7187	GO:0050909	denotes	taste
T1875	7125-7131	PR:000036337	denotes	Tas2rs
T1874	7071-7080	CHEBI:36357	denotes	compounds
T1873	7056-7070	GO:0050913	denotes	bitter-tasting
T1872	6985-7005	CL:0000209	denotes	taste receptor cells
T1871	6985-6990	GO:0050909	denotes	taste
T1870	6971-6981	GO:0010467	denotes	expression
T1869	6804-6808	PR:000036337	denotes	T2Rs
T1868	6780-6785	SO:0000704	denotes	genes
T1867	6774-6779	PR:000036337	denotes	Tas2r
T1866	6753-6758	GO:0050909	denotes	taste
T1865	6744-6768	PR:000036337	denotes	T2R-type taste receptors
T1864	6697-6716	CL:0000623	denotes	natural killer cell
T1863	6619-6624	SO:0000704	denotes	genes
T1862	6544-6547	SO:0000771	denotes	QTL
T1861	6469-6475	SO:0001026	denotes	genome
T1860	6151-6156	NCBITaxon:10088	denotes	mouse
T1859	6089-6092	SO:0000771	denotes	QTL
T1858	6068-6071	SO:0000771	denotes	QTL
T1857	5929-5934	GO:0050909	denotes	taste
T1856	5886-5890	NCBITaxon:10088	denotes	mice
T1855	5484-5487	SO:0000771	denotes	QTL
T1854	5353-5354	GO:0050909	denotes	s
T1853	5347-5350	SO:0000771	denotes	QTL
T1852	5330-5331	SO:0000771	denotes	T
T1851	4938-4944	SO:0001026	denotes	genome
T1850	4887-4890	SO:0000771	denotes	QTL
T1849	4826-4829	SO:0000771	denotes	QTL
T1848	4804-4810	SO:0001026	denotes	genome
T1847	4701-4704	SO:0000771	denotes	QTL
T1846	4679-4685	SO:0001026	denotes	genome
T1845	4606-4612	SO:0001026	denotes	genome
T1844	4488-4493	GO:0050909	denotes	taste
T1843	4460-4464	SO:0000771	denotes	QTLs
T1842	4360-4363	SO:0000771	denotes	QTL
T2520	9626-9634	PR:000016904	denotes	Tas2r124
T2519	9613-9621	PR:000016893	denotes	Tas2r106
T2518	9595-9602	SO:0001023	denotes	alleles
T2517	9589-9594	PR:000036337	denotes	Tas2r
T2516	9535-9546	SO:0000855	denotes	orthologues
T2515	9470-9477	SO:0000440	denotes	vectors
T2514	9429-9441	SO:0000006	denotes	PCR products
T2513	9416-9423	SO:0001026	denotes	genomic
T2512	9386-9391	PR:000036337	denotes	Tas2r
T2511	9317-9322	PR:000036337	denotes	Tas2r
T2510	9273-9281	SO:0000357	denotes	flanking
T2509	9200-9204	NCBITaxon:10088	denotes	mice
T2508	9125-9136	SO:0000336	denotes	pseudogenes
T2507	9119-9124	PR:000036337	denotes	Tas2r
T2506	9085-9091	PR:000036337	denotes	Tas2rs
T2505	9035-9040	GO:0050909	denotes	taste
T2504	8999-9004	PR:000036337	denotes	Tas2r
T2503	8790-8800	GO:0010467	denotes	expression
T2502	8775-8781	SO:0001023	denotes	allele
T2501	8769-8774	PR:000036337	denotes	Tas2r
T2500	8742-8760	SO:0005836	denotes	regulatory regions
T2499	8742-8752	GO:0065007	denotes	regulatory
T2498	8602-8608	SO:0001023	denotes	allele
T2497	8596-8601	PR:000036337	denotes	Tas2r
T2496	8576-8587	SO:0000195	denotes	coding exon
T2495	8533-8537	NCBITaxon:10088	denotes	mice
T2494	8451-8461	SO:0000336	denotes	pseudogene
T2493	8439-8445	SO:0001023	denotes	allele
T2492	8433-8438	PR:000036337	denotes	Tas2r
T2491	8370-8375	SO:0000704	denotes	genes
T2490	8364-8369	PR:000036337	denotes	Tas2r
T2489	8323-8326	SO:0000771	denotes	QTL
T2488	8305-8310	GO:0050909	denotes	taste
T2487	8267-8273	PR:000036337	denotes	Tas2rs
T2486	8242-8249	SO:0001023	denotes	alleles
T2485	8238-8241	PR:000036337	denotes	T2R
T1499	4193-4198	GO:0050909	denotes	taste
T1498	4069-4073	NCBITaxon:10088	denotes	mice
T1497	4022-4026	NCBITaxon:10088	denotes	mice
T1481	9-14	GO:0050909	denotes	Taste
T1482	47-50	SO:0000771	denotes	QTL
T1483	55-67	GO:0050913	denotes	bitter taste
T1484	82-93	GO:0007631	denotes	consumption
T1485	152-161	GO:0007631	denotes	ingestive
T1486	307-311	NCBITaxon:10088	denotes	mice
T1487	335-340	GO:0050909	denotes	taste
T1488	360-365	GO:0050909	denotes	taste
T1489	423-427	NCBITaxon:10088	denotes	mice
T1490	556-564	CHEBI:36357	denotes	compound
T1491	618-623	GO:0050909	denotes	taste
T1492	765-769	NCBITaxon:10088	denotes	mice
T1493	868-877	CHEBI:36357	denotes	compounds
T1494	1000-1004	NCBITaxon:10088	denotes	mice
T1495	1049-1053	NCBITaxon:10088	denotes	mice
T1496	1141-1146	GO:0050909	denotes	taste
T7342	1268-1272	NCBITaxon:10088	denotes	mice
T2529	10070-10081	SO:0000336	denotes	pseudogenes
T2528	10057-10062	SO:0000704	denotes	genes
T2527	9927-9935	PR:000016900	denotes	Tas2r117
T2526	9914-9922	PR:000016890	denotes	Tas2r103
T2525	9905-9912	SO:0001023	denotes	alleles
T2524	9892-9896	NCBITaxon:10088	denotes	mice
T2523	9869-9874	PR:000036337	denotes	Tas2r
T2522	9758-9765	SO:0001026	denotes	genomic
T2521	9717-9725	PR:000016902	denotes	Tas2r120

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