PMC:1166548 / 4084-4906 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1166548","sourcedb":"PMC","sourceid":"1166548","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1166548","text":"Previous work using human patients and genetically altered mice has identified some modifier genes and have advanced our understanding of CF pathophysiology [4]. In one study using CF mice on different genetic backgrounds, a region on mouse chromosome 7 was shown to ameliorate intestinal blockage and the effect was in part due to a calcium-regulated Cl-channel which compensated for loss of CFTR function [16,17]. Marker haplotypes of the syntenic region of human chromosome 19q13 were also shown to be associated with the risk of MI in CF patients [18]. In other work, a region on mouse chr. 6 was strongly associated with lung inflammation, consisting of mononuclear cell interstitial infiltration and fibrosis in CF mouse airways; and other loci on chr. 1, 2, 10, and 17 were also linked to the airway phenotype [19].","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T1147","span":{"begin":0,"end":8},"obj":"JJ"},{"id":"T1148","span":{"begin":9,"end":13},"obj":"NN"},{"id":"T1149","span":{"begin":68,"end":78},"obj":"VBN"},{"id":"T1150","span":{"begin":14,"end":19},"obj":"VBG"},{"id":"T1151","span":{"begin":20,"end":25},"obj":"JJ"},{"id":"T1152","span":{"begin":26,"end":34},"obj":"NNS"},{"id":"T1153","span":{"begin":35,"end":38},"obj":"CC"},{"id":"T1154","span":{"begin":39,"end":50},"obj":"RB"},{"id":"T1155","span":{"begin":51,"end":58},"obj":"VBN"},{"id":"T1156","span":{"begin":59,"end":63},"obj":"NNS"},{"id":"T1157","span":{"begin":64,"end":67},"obj":"VBZ"},{"id":"T1158","span":{"begin":79,"end":83},"obj":"DT"},{"id":"T1159","span":{"begin":93,"end":98},"obj":"NNS"},{"id":"T1160","span":{"begin":84,"end":92},"obj":"NN"},{"id":"T1161","span":{"begin":99,"end":102},"obj":"CC"},{"id":"T1162","span":{"begin":103,"end":107},"obj":"VBP"},{"id":"T1163","span":{"begin":108,"end":116},"obj":"VBN"},{"id":"T1164","span":{"begin":117,"end":120},"obj":"PRP$"},{"id":"T1165","span":{"begin":121,"end":134},"obj":"NN"},{"id":"T1166","span":{"begin":135,"end":137},"obj":"IN"},{"id":"T1167","span":{"begin":138,"end":140},"obj":"NN"},{"id":"T1168","span":{"begin":141,"end":156},"obj":"NN"},{"id":"T1169","span":{"begin":157,"end":158},"obj":"-LRB-"},{"id":"T1170","span":{"begin":158,"end":159},"obj":"CD"},{"id":"T1171","span":{"begin":159,"end":160},"obj":"-RRB-"},{"id":"T1172","span":{"begin":160,"end":161},"obj":"."},{"id":"T1173","span":{"begin":161,"end":415},"obj":"sentence"},{"id":"T1174","span":{"begin":162,"end":164},"obj":"IN"},{"id":"T1175","span":{"begin":258,"end":263},"obj":"VBN"},{"id":"T1176","span":{"begin":165,"end":168},"obj":"CD"},{"id":"T1177","span":{"begin":169,"end":174},"obj":"NN"},{"id":"T1178","span":{"begin":175,"end":180},"obj":"VBG"},{"id":"T1179","span":{"begin":181,"end":183},"obj":"NN"},{"id":"T1180","span":{"begin":184,"end":188},"obj":"NNS"},{"id":"T1181","span":{"begin":189,"end":191},"obj":"IN"},{"id":"T1182","span":{"begin":192,"end":201},"obj":"JJ"},{"id":"T1183","span":{"begin":210,"end":221},"obj":"NNS"},{"id":"T1184","span":{"begin":202,"end":209},"obj":"JJ"},{"id":"T1185","span":{"begin":221,"end":223},"obj":","},{"id":"T1186","span":{"begin":223,"end":224},"obj":"DT"},{"id":"T1187","span":{"begin":225,"end":231},"obj":"NN"},{"id":"T1188","span":{"begin":232,"end":234},"obj":"IN"},{"id":"T1189","span":{"begin":235,"end":240},"obj":"NN"},{"id":"T1190","span":{"begin":241,"end":251},"obj":"NN"},{"id":"T1191","span":{"begin":252,"end":253},"obj":"CD"},{"id":"T1192","span":{"begin":254,"end":257},"obj":"VBD"},{"id":"T1193","span":{"begin":264,"end":266},"obj":"TO"},{"id":"T1194","span":{"begin":267,"end":277},"obj":"VB"},{"id":"T1195","span":{"begin":278,"end":288},"obj":"JJ"},{"id":"T1196","span":{"begin":289,"end":297},"obj":"NN"},{"id":"T1197","span":{"begin":298,"end":301},"obj":"CC"},{"id":"T1198","span":{"begin":302,"end":305},"obj":"DT"},{"id":"T1199","span":{"begin":306,"end":312},"obj":"NN"},{"id":"T1200","span":{"begin":313,"end":316},"obj":"VBD"},{"id":"T1201","span":{"begin":317,"end":319},"obj":"IN"},{"id":"T1202","span":{"begin":320,"end":324},"obj":"JJ"},{"id":"T1203","span":{"begin":325,"end":328},"obj":"IN"},{"id":"T1204","span":{"begin":329,"end":331},"obj":"IN"},{"id":"T1205","span":{"begin":332,"end":333},"obj":"DT"},{"id":"T1206","span":{"begin":355,"end":362},"obj":"NN"},{"id":"T1207","span":{"begin":334,"end":341},"obj":"NN"},{"id":"T1208","span":{"begin":342,"end":351},"obj":"VBN"},{"id":"T1209","span":{"begin":341,"end":342},"obj":"HYPH"},{"id":"T1210","span":{"begin":352,"end":354},"obj":"NN"},{"id":"T1211","span":{"begin":354,"end":355},"obj":"SYM"},{"id":"T1212","span":{"begin":363,"end":368},"obj":"WDT"},{"id":"T1213","span":{"begin":369,"end":380},"obj":"VBD"},{"id":"T1214","span":{"begin":381,"end":384},"obj":"IN"},{"id":"T1215","span":{"begin":385,"end":389},"obj":"NN"},{"id":"T1216","span":{"begin":390,"end":392},"obj":"IN"},{"id":"T1217","span":{"begin":393,"end":397},"obj":"NN"},{"id":"T1218","span":{"begin":398,"end":406},"obj":"NN"},{"id":"T1219","span":{"begin":407,"end":408},"obj":"-LRB-"},{"id":"T1220","span":{"begin":411,"end":413},"obj":"CD"},{"id":"T1221","span":{"begin":408,"end":410},"obj":"CD"},{"id":"T1222","span":{"begin":410,"end":411},"obj":","},{"id":"T1223","span":{"begin":413,"end":414},"obj":"-RRB-"},{"id":"T1224","span":{"begin":414,"end":415},"obj":"."},{"id":"T1225","span":{"begin":415,"end":556},"obj":"sentence"},{"id":"T1226","span":{"begin":416,"end":422},"obj":"NN"},{"id":"T1227","span":{"begin":423,"end":433},"obj":"NNS"},{"id":"T1228","span":{"begin":493,"end":498},"obj":"VBN"},{"id":"T1229","span":{"begin":434,"end":436},"obj":"IN"},{"id":"T1230","span":{"begin":437,"end":440},"obj":"DT"},{"id":"T1231","span":{"begin":450,"end":456},"obj":"NN"},{"id":"T1232","span":{"begin":441,"end":449},"obj":"JJ"},{"id":"T1233","span":{"begin":457,"end":459},"obj":"IN"},{"id":"T1234","span":{"begin":460,"end":465},"obj":"JJ"},{"id":"T1235","span":{"begin":466,"end":476},"obj":"NN"},{"id":"T1236","span":{"begin":477,"end":482},"obj":"CD"},{"id":"T1237","span":{"begin":483,"end":487},"obj":"VBD"},{"id":"T1238","span":{"begin":488,"end":492},"obj":"RB"},{"id":"T1239","span":{"begin":499,"end":501},"obj":"TO"},{"id":"T1240","span":{"begin":505,"end":515},"obj":"VBN"},{"id":"T1241","span":{"begin":502,"end":504},"obj":"VB"},{"id":"T1242","span":{"begin":516,"end":520},"obj":"IN"},{"id":"T1243","span":{"begin":521,"end":524},"obj":"DT"},{"id":"T1244","span":{"begin":525,"end":529},"obj":"NN"},{"id":"T1245","span":{"begin":530,"end":532},"obj":"IN"},{"id":"T1246","span":{"begin":533,"end":535},"obj":"NN"},{"id":"T1247","span":{"begin":536,"end":538},"obj":"IN"},{"id":"T1248","span":{"begin":539,"end":541},"obj":"NN"},{"id":"T1249","span":{"begin":542,"end":550},"obj":"NNS"},{"id":"T1250","span":{"begin":551,"end":552},"obj":"-LRB-"},{"id":"T1251","span":{"begin":552,"end":554},"obj":"CD"},{"id":"T1252","span":{"begin":554,"end":555},"obj":"-RRB-"},{"id":"T1253","span":{"begin":555,"end":556},"obj":"."},{"id":"T1254","span":{"begin":556,"end":822},"obj":"sentence"},{"id":"T1255","span":{"begin":557,"end":559},"obj":"IN"},{"id":"T1256","span":{"begin":610,"end":620},"obj":"VBN"},{"id":"T1257","span":{"begin":560,"end":565},"obj":"JJ"},{"id":"T1258","span":{"begin":566,"end":570},"obj":"NN"},{"id":"T1259","span":{"begin":570,"end":572},"obj":","},{"id":"T1260","span":{"begin":572,"end":573},"obj":"DT"},{"id":"T1261","span":{"begin":574,"end":580},"obj":"NN"},{"id":"T1262","span":{"begin":581,"end":583},"obj":"IN"},{"id":"T1263","span":{"begin":584,"end":589},"obj":"NN"},{"id":"T1264","span":{"begin":590,"end":594},"obj":"NN"},{"id":"T1265","span":{"begin":595,"end":596},"obj":"CD"},{"id":"T1266","span":{"begin":597,"end":600},"obj":"VBD"},{"id":"T1267","span":{"begin":601,"end":609},"obj":"RB"},{"id":"T1268","span":{"begin":621,"end":625},"obj":"IN"},{"id":"T1269","span":{"begin":626,"end":630},"obj":"NN"},{"id":"T1270","span":{"begin":631,"end":643},"obj":"NN"},{"id":"T1271","span":{"begin":643,"end":645},"obj":","},{"id":"T1272","span":{"begin":645,"end":655},"obj":"VBG"},{"id":"T1273","span":{"begin":656,"end":658},"obj":"IN"},{"id":"T1274","span":{"begin":659,"end":670},"obj":"JJ"},{"id":"T1275","span":{"begin":671,"end":675},"obj":"NN"},{"id":"T1276","span":{"begin":689,"end":701},"obj":"NN"},{"id":"T1277","span":{"begin":676,"end":688},"obj":"JJ"},{"id":"T1278","span":{"begin":702,"end":705},"obj":"CC"},{"id":"T1279","span":{"begin":706,"end":714},"obj":"NN"},{"id":"T1280","span":{"begin":715,"end":717},"obj":"IN"},{"id":"T1281","span":{"begin":718,"end":720},"obj":"NN"},{"id":"T1282","span":{"begin":727,"end":734},"obj":"NNS"},{"id":"T1283","span":{"begin":721,"end":726},"obj":"NN"},{"id":"T1284","span":{"begin":734,"end":735},"obj":":"},{"id":"T1285","span":{"begin":736,"end":739},"obj":"CC"},{"id":"T1286","span":{"begin":740,"end":745},"obj":"JJ"},{"id":"T1287","span":{"begin":746,"end":750},"obj":"NNS"},{"id":"T1288","span":{"begin":786,"end":792},"obj":"VBN"},{"id":"T1289","span":{"begin":751,"end":753},"obj":"IN"},{"id":"T1290","span":{"begin":754,"end":758},"obj":"NN"},{"id":"T1291","span":{"begin":759,"end":760},"obj":"CD"},{"id":"T1292","span":{"begin":760,"end":762},"obj":","},{"id":"T1293","span":{"begin":762,"end":763},"obj":"CD"},{"id":"T1294","span":{"begin":763,"end":765},"obj":","},{"id":"T1295","span":{"begin":765,"end":767},"obj":"CD"},{"id":"T1296","span":{"begin":767,"end":769},"obj":","},{"id":"T1297","span":{"begin":769,"end":772},"obj":"CC"},{"id":"T1298","span":{"begin":773,"end":775},"obj":"CD"},{"id":"T1299","span":{"begin":776,"end":780},"obj":"VBD"},{"id":"T1300","span":{"begin":781,"end":785},"obj":"RB"},{"id":"T1301","span":{"begin":793,"end":795},"obj":"IN"},{"id":"T1302","span":{"begin":796,"end":799},"obj":"DT"},{"id":"T1303","span":{"begin":807,"end":816},"obj":"NN"},{"id":"T1304","span":{"begin":800,"end":806},"obj":"NN"},{"id":"T1305","span":{"begin":817,"end":818},"obj":"-LRB-"},{"id":"T1306","span":{"begin":818,"end":820},"obj":"CD"},{"id":"T1307","span":{"begin":820,"end":821},"obj":"-RRB-"},{"id":"T1308","span":{"begin":821,"end":822},"obj":"."}],"relations":[{"id":"R714","pred":"amod","subj":"T1147","obj":"T1148"},{"id":"R715","pred":"nsubj","subj":"T1148","obj":"T1149"},{"id":"R716","pred":"acl","subj":"T1150","obj":"T1148"},{"id":"R717","pred":"amod","subj":"T1151","obj":"T1152"},{"id":"R718","pred":"dobj","subj":"T1152","obj":"T1150"},{"id":"R719","pred":"cc","subj":"T1153","obj":"T1152"},{"id":"R720","pred":"advmod","subj":"T1154","obj":"T1155"},{"id":"R721","pred":"amod","subj":"T1155","obj":"T1156"},{"id":"R722","pred":"conj","subj":"T1156","obj":"T1152"},{"id":"R723","pred":"aux","subj":"T1157","obj":"T1149"},{"id":"R724","pred":"det","subj":"T1158","obj":"T1159"},{"id":"R725","pred":"dobj","subj":"T1159","obj":"T1149"},{"id":"R726","pred":"compound","subj":"T1160","obj":"T1159"},{"id":"R727","pred":"cc","subj":"T1161","obj":"T1149"},{"id":"R728","pred":"aux","subj":"T1162","obj":"T1163"},{"id":"R729","pred":"conj","subj":"T1163","obj":"T1149"},{"id":"R730","pred":"poss","subj":"T1164","obj":"T1165"},{"id":"R731","pred":"dobj","subj":"T1165","obj":"T1163"},{"id":"R732","pred":"prep","subj":"T1166","obj":"T1165"},{"id":"R733","pred":"compound","subj":"T1167","obj":"T1168"},{"id":"R734","pred":"pobj","subj":"T1168","obj":"T1166"},{"id":"R735","pred":"punct","subj":"T1169","obj":"T1170"},{"id":"R736","pred":"parataxis","subj":"T1170","obj":"T1163"},{"id":"R737","pred":"punct","subj":"T1171","obj":"T1170"},{"id":"R738","pred":"punct","subj":"T1172","obj":"T1149"},{"id":"R739","pred":"prep","subj":"T1174","obj":"T1175"},{"id":"R740","pred":"nummod","subj":"T1176","obj":"T1177"},{"id":"R741","pred":"pobj","subj":"T1177","obj":"T1174"},{"id":"R742","pred":"acl","subj":"T1178","obj":"T1177"},{"id":"R743","pred":"compound","subj":"T1179","obj":"T1180"},{"id":"R744","pred":"dobj","subj":"T1180","obj":"T1178"},{"id":"R745","pred":"prep","subj":"T1181","obj":"T1180"},{"id":"R746","pred":"amod","subj":"T1182","obj":"T1183"},{"id":"R747","pred":"pobj","subj":"T1183","obj":"T1181"},{"id":"R748","pred":"amod","subj":"T1184","obj":"T1183"},{"id":"R749","pred":"punct","subj":"T1185","obj":"T1175"},{"id":"R750","pred":"det","subj":"T1186","obj":"T1187"},{"id":"R751","pred":"nsubjpass","subj":"T1187","obj":"T1175"},{"id":"R752","pred":"prep","subj":"T1188","obj":"T1187"},{"id":"R753","pred":"compound","subj":"T1189","obj":"T1190"},{"id":"R754","pred":"pobj","subj":"T1190","obj":"T1188"},{"id":"R755","pred":"nummod","subj":"T1191","obj":"T1190"},{"id":"R756","pred":"auxpass","subj":"T1192","obj":"T1175"},{"id":"R757","pred":"aux","subj":"T1193","obj":"T1194"},{"id":"R758","pred":"xcomp","subj":"T1194","obj":"T1175"},{"id":"R759","pred":"amod","subj":"T1195","obj":"T1196"},{"id":"R760","pred":"dobj","subj":"T1196","obj":"T1194"},{"id":"R761","pred":"cc","subj":"T1197","obj":"T1175"},{"id":"R762","pred":"det","subj":"T1198","obj":"T1199"},{"id":"R763","pred":"nsubj","subj":"T1199","obj":"T1200"},{"id":"R764","pred":"conj","subj":"T1200","obj":"T1175"},{"id":"R765","pred":"prep","subj":"T1201","obj":"T1200"},{"id":"R766","pred":"amod","subj":"T1202","obj":"T1201"},{"id":"R767","pred":"prep","subj":"T1203","obj":"T1200"},{"id":"R768","pred":"pcomp","subj":"T1204","obj":"T1203"},{"id":"R769","pred":"det","subj":"T1205","obj":"T1206"},{"id":"R770","pred":"pobj","subj":"T1206","obj":"T1203"},{"id":"R771","pred":"npadvmod","subj":"T1207","obj":"T1208"},{"id":"R772","pred":"amod","subj":"T1208","obj":"T1206"},{"id":"R773","pred":"punct","subj":"T1209","obj":"T1208"},{"id":"R774","pred":"nmod","subj":"T1210","obj":"T1206"},{"id":"R775","pred":"punct","subj":"T1211","obj":"T1206"},{"id":"R776","pred":"dep","subj":"T1212","obj":"T1213"},{"id":"R777","pred":"relcl","subj":"T1213","obj":"T1206"},{"id":"R778","pred":"prep","subj":"T1214","obj":"T1213"},{"id":"R779","pred":"pobj","subj":"T1215","obj":"T1214"},{"id":"R780","pred":"prep","subj":"T1216","obj":"T1215"},{"id":"R781","pred":"compound","subj":"T1217","obj":"T1218"},{"id":"R782","pred":"pobj","subj":"T1218","obj":"T1216"},{"id":"R783","pred":"punct","subj":"T1219","obj":"T1220"},{"id":"R784","pred":"parataxis","subj":"T1220","obj":"T1200"},{"id":"R785","pred":"nummod","subj":"T1221","obj":"T1220"},{"id":"R786","pred":"punct","subj":"T1222","obj":"T1220"},{"id":"R787","pred":"punct","subj":"T1223","obj":"T1220"},{"id":"R788","pred":"punct","subj":"T1224","obj":"T1200"},{"id":"R789","pred":"compound","subj":"T1226","obj":"T1227"},{"id":"R790","pred":"nsubjpass","subj":"T1227","obj":"T1228"},{"id":"R791","pred":"prep","subj":"T1229","obj":"T1227"},{"id":"R792","pred":"det","subj":"T1230","obj":"T1231"},{"id":"R793","pred":"pobj","subj":"T1231","obj":"T1229"},{"id":"R794","pred":"amod","subj":"T1232","obj":"T1231"},{"id":"R795","pred":"prep","subj":"T1233","obj":"T1231"},{"id":"R796","pred":"amod","subj":"T1234","obj":"T1235"},{"id":"R797","pred":"pobj","subj":"T1235","obj":"T1233"},{"id":"R798","pred":"nummod","subj":"T1236","obj":"T1235"},{"id":"R799","pred":"auxpass","subj":"T1237","obj":"T1228"},{"id":"R800","pred":"advmod","subj":"T1238","obj":"T1228"},{"id":"R801","pred":"aux","subj":"T1239","obj":"T1240"},{"id":"R802","pred":"xcomp","subj":"T1240","obj":"T1228"},{"id":"R803","pred":"auxpass","subj":"T1241","obj":"T1240"},{"id":"R804","pred":"prep","subj":"T1242","obj":"T1240"},{"id":"R805","pred":"det","subj":"T1243","obj":"T1244"},{"id":"R806","pred":"pobj","subj":"T1244","obj":"T1242"},{"id":"R807","pred":"prep","subj":"T1245","obj":"T1244"},{"id":"R808","pred":"pobj","subj":"T1246","obj":"T1245"},{"id":"R809","pred":"prep","subj":"T1247","obj":"T1240"},{"id":"R810","pred":"compound","subj":"T1248","obj":"T1249"},{"id":"R811","pred":"pobj","subj":"T1249","obj":"T1247"},{"id":"R812","pred":"punct","subj":"T1250","obj":"T1251"},{"id":"R813","pred":"parataxis","subj":"T1251","obj":"T1228"},{"id":"R814","pred":"punct","subj":"T1252","obj":"T1251"},{"id":"R815","pred":"punct","subj":"T1253","obj":"T1228"},{"id":"R816","pred":"prep","subj":"T1255","obj":"T1256"},{"id":"R817","pred":"amod","subj":"T1257","obj":"T1258"},{"id":"R818","pred":"pobj","subj":"T1258","obj":"T1255"},{"id":"R819","pred":"punct","subj":"T1259","obj":"T1256"},{"id":"R820","pred":"det","subj":"T1260","obj":"T1261"},{"id":"R821","pred":"nsubjpass","subj":"T1261","obj":"T1256"},{"id":"R822","pred":"prep","subj":"T1262","obj":"T1261"},{"id":"R823","pred":"compound","subj":"T1263","obj":"T1264"},{"id":"R824","pred":"pobj","subj":"T1264","obj":"T1262"},{"id":"R825","pred":"nummod","subj":"T1265","obj":"T1264"},{"id":"R826","pred":"auxpass","subj":"T1266","obj":"T1256"},{"id":"R827","pred":"advmod","subj":"T1267","obj":"T1256"},{"id":"R828","pred":"prep","subj":"T1268","obj":"T1256"},{"id":"R829","pred":"compound","subj":"T1269","obj":"T1270"},{"id":"R830","pred":"pobj","subj":"T1270","obj":"T1268"},{"id":"R831","pred":"punct","subj":"T1271","obj":"T1270"},{"id":"R832","pred":"acl","subj":"T1272","obj":"T1270"},{"id":"R833","pred":"prep","subj":"T1273","obj":"T1272"},{"id":"R834","pred":"amod","subj":"T1274","obj":"T1275"},{"id":"R835","pred":"nmod","subj":"T1275","obj":"T1276"},{"id":"R836","pred":"pobj","subj":"T1276","obj":"T1273"},{"id":"R837","pred":"amod","subj":"T1277","obj":"T1276"},{"id":"R838","pred":"cc","subj":"T1278","obj":"T1276"},{"id":"R839","pred":"conj","subj":"T1279","obj":"T1276"},{"id":"R840","pred":"prep","subj":"T1280","obj":"T1272"},{"id":"R841","pred":"compound","subj":"T1281","obj":"T1282"},{"id":"R842","pred":"pobj","subj":"T1282","obj":"T1280"},{"id":"R843","pred":"compound","subj":"T1283","obj":"T1282"},{"id":"R844","pred":"punct","subj":"T1284","obj":"T1256"},{"id":"R845","pred":"cc","subj":"T1285","obj":"T1256"},{"id":"R846","pred":"amod","subj":"T1286","obj":"T1287"},{"id":"R847","pred":"nsubjpass","subj":"T1287","obj":"T1288"},{"id":"R848","pred":"conj","subj":"T1288","obj":"T1256"},{"id":"R849","pred":"prep","subj":"T1289","obj":"T1287"},{"id":"R850","pred":"nmod","subj":"T1290","obj":"T1291"},{"id":"R851","pred":"pobj","subj":"T1291","obj":"T1289"},{"id":"R852","pred":"punct","subj":"T1292","obj":"T1291"},{"id":"R853","pred":"conj","subj":"T1293","obj":"T1291"},{"id":"R854","pred":"punct","subj":"T1294","obj":"T1293"},{"id":"R855","pred":"conj","subj":"T1295","obj":"T1293"},{"id":"R856","pred":"punct","subj":"T1296","obj":"T1295"},{"id":"R857","pred":"cc","subj":"T1297","obj":"T1295"},{"id":"R858","pred":"conj","subj":"T1298","obj":"T1295"},{"id":"R859","pred":"auxpass","subj":"T1299","obj":"T1288"},{"id":"R860","pred":"advmod","subj":"T1300","obj":"T1288"},{"id":"R861","pred":"prep","subj":"T1301","obj":"T1288"},{"id":"R862","pred":"det","subj":"T1302","obj":"T1303"},{"id":"R863","pred":"pobj","subj":"T1303","obj":"T1301"},{"id":"R864","pred":"compound","subj":"T1304","obj":"T1303"},{"id":"R865","pred":"punct","subj":"T1305","obj":"T1306"},{"id":"R866","pred":"parataxis","subj":"T1306","obj":"T1288"},{"id":"R867","pred":"punct","subj":"T1307","obj":"T1306"},{"id":"R868","pred":"punct","subj":"T1308","obj":"T1256"}],"attributes":[{"subj":"T1147","pred":"source","obj":"craft-sa-dev"},{"subj":"T1148","pred":"source","obj":"craft-sa-dev"},{"subj":"T1149","pred":"source","obj":"craft-sa-dev"},{"subj":"T1150","pred":"source","obj":"craft-sa-dev"},{"subj":"T1151","pred":"source","obj":"craft-sa-dev"},{"subj":"T1152","pred":"source","obj":"craft-sa-dev"},{"subj":"T1153","pred":"source","obj":"craft-sa-dev"},{"subj":"T1154","pred":"source","obj":"craft-sa-dev"},{"subj":"T1155","pred":"source","obj":"craft-sa-dev"},{"subj":"T1156","pred":"source","obj":"craft-sa-dev"},{"subj":"T1157","pred":"source","obj":"craft-sa-dev"},{"subj":"T1158","pred":"source","obj":"craft-sa-dev"},{"subj":"T1159","pred":"source","obj":"craft-sa-dev"},{"subj":"T1160","pred":"source","obj":"craft-sa-dev"},{"subj":"T1161","pred":"source","obj":"craft-sa-dev"},{"subj":"T1162","pred":"source","obj":"craft-sa-dev"},{"subj":"T1163","pred":"source","obj":"craft-sa-dev"},{"subj":"T1164","pred":"source","obj":"craft-sa-dev"},{"subj":"T1165","pred":"source","obj":"craft-sa-dev"},{"subj":"T1166","pred":"source","obj":"craft-sa-dev"},{"subj":"T1167","pred":"source","obj":"craft-sa-dev"},{"subj":"T1168","pred":"source","obj":"craft-sa-dev"},{"subj":"T1169","pred":"source","obj":"craft-sa-dev"},{"subj":"T1170","pred":"source","obj":"craft-sa-dev"},{"subj":"T1171","pred":"source","obj":"craft-sa-dev"},{"subj":"T1172","pred":"source","obj":"craft-sa-dev"},{"subj":"T1173","pred":"source","obj":"craft-sa-dev"},{"subj":"T1174","pred":"source","obj":"craft-sa-dev"},{"subj":"T1175","pred":"source","obj":"craft-sa-dev"},{"subj":"T1176","pred":"source","obj":"craft-sa-dev"},{"subj":"T1177","pred":"source","obj":"craft-sa-dev"},{"subj":"T1178","pred":"source","obj":"craft-sa-dev"},{"subj":"T1179","pred":"source","obj":"craft-sa-dev"},{"subj":"T1180","pred":"source","obj":"craft-sa-dev"},{"subj":"T1181","pred":"source","obj":"craft-sa-dev"},{"subj":"T1182","pred":"source","obj":"craft-sa-dev"},{"subj":"T1183","pred":"source","obj":"craft-sa-dev"},{"subj":"T1184","pred":"source","obj":"craft-sa-dev"},{"subj":"T1185","pred":"source","obj":"craft-sa-dev"},{"subj":"T1186","pred":"source","obj":"craft-sa-dev"},{"subj":"T1187","pred":"source","obj":"craft-sa-dev"},{"subj":"T1188","pred":"source","obj":"craft-sa-dev"},{"subj":"T1189","pred":"source","obj":"craft-sa-dev"},{"subj":"T1190","pred":"source","obj":"craft-sa-dev"},{"subj":"T1191","pred":"source","obj":"craft-sa-dev"},{"subj":"T1192","pred":"source","obj":"craft-sa-dev"},{"subj":"T1193","pred":"source","obj":"craft-sa-dev"},{"subj":"T1194","pred":"source","obj":"craft-sa-dev"},{"subj":"T1195","pred":"source","obj":"craft-sa-dev"},{"subj":"T1196","pred":"source","obj":"craft-sa-dev"},{"subj":"T1197","pred":"source","obj":"craft-sa-dev"},{"subj":"T1198","pred":"source","obj":"craft-sa-dev"},{"subj":"T1199","pred":"source","obj":"craft-sa-dev"},{"subj":"T1200","pred":"source","obj":"craft-sa-dev"},{"subj":"T1201","pred":"source","obj":"craft-sa-dev"},{"subj":"T1202","pred":"source","obj":"craft-sa-dev"},{"subj":"T1203","pred":"source","obj":"craft-sa-dev"},{"subj":"T1204","pred":"source","obj":"craft-sa-dev"},{"subj":"T1205","pred":"source","obj":"craft-sa-dev"},{"subj":"T1206","pred":"source","obj":"craft-sa-dev"},{"subj":"T1207","pred":"source","obj":"craft-sa-dev"},{"subj":"T1208","pred":"source","obj":"craft-sa-dev"},{"subj":"T1209","pred":"source","obj":"craft-sa-dev"},{"subj":"T1210","pred":"source","obj":"craft-sa-dev"},{"subj":"T1211","pred":"source","obj":"craft-sa-dev"},{"subj":"T1212","pred":"source","obj":"craft-sa-dev"},{"subj":"T1213","pred":"source","obj":"craft-sa-dev"},{"subj":"T1214","pred":"source","obj":"craft-sa-dev"},{"subj":"T1215","pred":"source","obj":"craft-sa-dev"},{"subj":"T1216","pred":"source","obj":"craft-sa-dev"},{"subj":"T1217","pred":"source","obj":"craft-sa-dev"},{"subj":"T1218","pred":"source","obj":"craft-sa-dev"},{"subj":"T1219","pred":"source","obj":"craft-sa-dev"},{"subj":"T1220","pred":"source","obj":"craft-sa-dev"},{"subj":"T1221","pred":"source","obj":"craft-sa-dev"},{"subj":"T1222","pred":"source","obj":"craft-sa-dev"},{"subj":"T1223","pred":"source","obj":"craft-sa-dev"},{"subj":"T1224","pred":"source","obj":"craft-sa-dev"},{"subj":"T1225","pred":"source","obj":"craft-sa-dev"},{"subj":"T1226","pred":"source","obj":"craft-sa-dev"},{"subj":"T1227","pred":"source","obj":"craft-sa-dev"},{"subj":"T1228","pred":"source","obj":"craft-sa-dev"},{"subj":"T1229","pred":"source","obj":"craft-sa-dev"},{"subj":"T1230","pred":"source","obj":"craft-sa-dev"},{"subj":"T1231","pred":"source","obj":"craft-sa-dev"},{"subj":"T1232","pred":"source","obj":"craft-sa-dev"},{"subj":"T1233","pred":"source","obj":"craft-sa-dev"},{"subj":"T1234","pred":"source","obj":"craft-sa-dev"},{"subj":"T1235","pred":"source","obj":"craft-sa-dev"},{"subj":"T1236","pred":"source","obj":"craft-sa-dev"},{"subj":"T1237","pred":"source","obj":"craft-sa-dev"},{"subj":"T1238","pred":"source","obj":"craft-sa-dev"},{"subj":"T1239","pred":"source","obj":"craft-sa-dev"},{"subj":"T1240","pred":"source","obj":"craft-sa-dev"},{"subj":"T1241","pred":"source","obj":"craft-sa-dev"},{"subj":"T1242","pred":"source","obj":"craft-sa-dev"},{"subj":"T1243","pred":"source","obj":"craft-sa-dev"},{"subj":"T1244","pred":"source","obj":"craft-sa-dev"},{"subj":"T1245","pred":"source","obj":"craft-sa-dev"},{"subj":"T1246","pred":"source","obj":"craft-sa-dev"},{"subj":"T1247","pred":"source","obj":"craft-sa-dev"},{"subj":"T1248","pred":"source","obj":"craft-sa-dev"},{"subj":"T1249","pred":"source","obj":"craft-sa-dev"},{"subj":"T1250","pred":"source","obj":"craft-sa-dev"},{"subj":"T1251","pred":"source","obj":"craft-sa-dev"},{"subj":"T1252","pred":"source","obj":"craft-sa-dev"},{"subj":"T1253","pred":"source","obj":"craft-sa-dev"},{"subj":"T1254","pred":"source","obj":"craft-sa-dev"},{"subj":"T1255","pred":"source","obj":"craft-sa-dev"},{"subj":"T1256","pred":"source","obj":"craft-sa-dev"},{"subj":"T1257","pred":"source","obj":"craft-sa-dev"},{"subj":"T1258","pred":"source","obj":"craft-sa-dev"},{"subj":"T1259","pred":"source","obj":"craft-sa-dev"},{"subj":"T1260","pred":"source","obj":"craft-sa-dev"},{"subj":"T1261","pred":"source","obj":"craft-sa-dev"},{"subj":"T1262","pred":"source","obj":"craft-sa-dev"},{"subj":"T1263","pred":"source","obj":"craft-sa-dev"},{"subj":"T1264","pred":"source","obj":"craft-sa-dev"},{"subj":"T1265","pred":"source","obj":"craft-sa-dev"},{"subj":"T1266","pred":"source","obj":"craft-sa-dev"},{"subj":"T1267","pred":"source","obj":"craft-sa-dev"},{"subj":"T1268","pred":"source","obj":"craft-sa-dev"},{"subj":"T1269","pred":"source","obj":"craft-sa-dev"},{"subj":"T1270","pred":"source","obj":"craft-sa-dev"},{"subj":"T1271","pred":"source","obj":"craft-sa-dev"},{"subj":"T1272","pred":"source","obj":"craft-sa-dev"},{"subj":"T1273","pred":"source","obj":"craft-sa-dev"},{"subj":"T1274","pred":"source","obj":"craft-sa-dev"},{"subj":"T1275","pred":"source","obj":"craft-sa-dev"},{"subj":"T1276","pred":"source","obj":"craft-sa-dev"},{"subj":"T1277","pred":"source","obj":"craft-sa-dev"},{"subj":"T1278","pred":"source","obj":"craft-sa-dev"},{"subj":"T1279","pred":"source","obj":"craft-sa-dev"},{"subj":"T1280","pred":"source","obj":"craft-sa-dev"},{"subj":"T1281","pred":"source","obj":"craft-sa-dev"},{"subj":"T1282","pred":"source","obj":"craft-sa-dev"},{"subj":"T1283","pred":"source","obj":"craft-sa-dev"},{"subj":"T1284","pred":"source","obj":"craft-sa-dev"},{"subj":"T1285","pred":"source","obj":"craft-sa-dev"},{"subj":"T1286","pred":"source","obj":"craft-sa-dev"},{"subj":"T1287","pred":"source","obj":"craft-sa-dev"},{"subj":"T1288","pred":"source","obj":"craft-sa-dev"},{"subj":"T1289","pred":"source","obj":"craft-sa-dev"},{"subj":"T1290","pred":"source","obj":"craft-sa-dev"},{"subj":"T1291","pred":"source","obj":"craft-sa-dev"},{"subj":"T1292","pred":"source","obj":"craft-sa-dev"},{"subj":"T1293","pred":"source","obj":"craft-sa-dev"},{"subj":"T1294","pred":"source","obj":"craft-sa-dev"},{"subj":"T1295","pred":"source","obj":"craft-sa-dev"},{"subj":"T1296","pred":"source","obj":"craft-sa-dev"},{"subj":"T1297","pred":"source","obj":"craft-sa-dev"},{"subj":"T1298","pred":"source","obj":"craft-sa-dev"},{"subj":"T1299","pred":"source","obj":"craft-sa-dev"},{"subj":"T1300","pred":"source","obj":"craft-sa-dev"},{"subj":"T1301","pred":"source","obj":"craft-sa-dev"},{"subj":"T1302","pred":"source","obj":"craft-sa-dev"},{"subj":"T1303","pred":"source","obj":"craft-sa-dev"},{"subj":"T1304","pred":"source","obj":"craft-sa-dev"},{"subj":"T1305","pred":"source","obj":"craft-sa-dev"},{"subj":"T1306","pred":"source","obj":"craft-sa-dev"},{"subj":"T1307","pred":"source","obj":"craft-sa-dev"},{"subj":"T1308","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T740","span":{"begin":20,"end":25},"obj":"NCBITaxon:9606"},{"id":"T741","span":{"begin":39,"end":50},"obj":"SO_EXT:0000704"},{"id":"T742","span":{"begin":51,"end":58},"obj":"SO_EXT:sequence_alteration_process"},{"id":"T743","span":{"begin":59,"end":63},"obj":"NCBITaxon:10088"},{"id":"T744","span":{"begin":93,"end":98},"obj":"SO_EXT:0000704"},{"id":"T745","span":{"begin":184,"end":188},"obj":"NCBITaxon:10088"},{"id":"T746","span":{"begin":202,"end":209},"obj":"SO_EXT:0000704"},{"id":"T747","span":{"begin":225,"end":234},"obj":"_FRAGMENT"},{"id":"T748","span":{"begin":241,"end":251},"obj":"GO_SO_EXT:chromosomal_part_or_position_or_region_or_site"},{"id":"T749","span":{"begin":235,"end":240},"obj":"NCBITaxon:10088"},{"id":"T750","span":{"begin":278,"end":288},"obj":"UBERON:0000160"},{"id":"T751","span":{"begin":334,"end":341},"obj":"CHEBI_EXT:calcium"},{"id":"T752","span":{"begin":342,"end":351},"obj":"GO:0065007"},{"id":"T753","span":{"begin":352,"end":354},"obj":"CHEBI_EXT:chlorine"},{"id":"T754","span":{"begin":352,"end":362},"obj":"GO_EXT:0005254"},{"id":"T755","span":{"begin":393,"end":397},"obj":"PR_EXT:000001044"},{"id":"T756","span":{"begin":416,"end":422},"obj":"CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag"},{"id":"T757","span":{"begin":423,"end":433},"obj":"SO_EXT:0001024"},{"id":"T758","span":{"begin":441,"end":456},"obj":"SO_EXT:0005858"},{"id":"T759","span":{"begin":450,"end":459},"obj":"_FRAGMENT"},{"id":"T760","span":{"begin":466,"end":476},"obj":"GO_SO_EXT:chromosomal_part_or_position_or_region_or_site"},{"id":"T761","span":{"begin":460,"end":465},"obj":"NCBITaxon:9606"},{"id":"T762","span":{"begin":574,"end":583},"obj":"_FRAGMENT"},{"id":"T763","span":{"begin":590,"end":594},"obj":"GO_SO_EXT:chromosomal_part_or_position_or_region_or_site"},{"id":"T764","span":{"begin":584,"end":589},"obj":"NCBITaxon:10088"},{"id":"T765","span":{"begin":626,"end":630},"obj":"UBERON:0002048"},{"id":"T766","span":{"begin":631,"end":643},"obj":"GO_PATO_EXT:inflammatory_process_or_quality"},{"id":"T767","span":{"begin":659,"end":675},"obj":"CL:0000842"},{"id":"T768","span":{"begin":663,"end":670},"obj":"GO:0005634"},{"id":"T769","span":{"begin":671,"end":675},"obj":"CL_GO_EXT:cell"},{"id":"T770","span":{"begin":676,"end":688},"obj":"UBERON:0005169"},{"id":"T771","span":{"begin":721,"end":726},"obj":"NCBITaxon:10088"},{"id":"T772","span":{"begin":727,"end":734},"obj":"UBERON:0001005"},{"id":"T773","span":{"begin":746,"end":758},"obj":"GO_SO_EXT:chromosomal_part_or_position_or_region_or_site"},{"id":"T774","span":{"begin":800,"end":806},"obj":"UBERON:0001005"}],"relations":[{"id":"R376","pred":"_lexicallyChainedTo","subj":"T748","obj":"T747"},{"id":"R377","pred":"_lexicallyChainedTo","subj":"T760","obj":"T759"},{"id":"R378","pred":"_lexicallyChainedTo","subj":"T763","obj":"T762"}],"attributes":[{"subj":"T740","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T741","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T742","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T743","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T744","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T745","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T746","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T747","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T748","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T749","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T750","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T751","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T752","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T753","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T754","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T755","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T756","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T757","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T758","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T759","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T760","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T761","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T762","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T763","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T764","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T765","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T766","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T767","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T768","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T769","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T770","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T771","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T772","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T773","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T774","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T646","span":{"begin":20,"end":25},"obj":"NCBITaxon:9606"},{"id":"T647","span":{"begin":39,"end":50},"obj":"SO:0000704"},{"id":"T648","span":{"begin":59,"end":63},"obj":"NCBITaxon:10088"},{"id":"T649","span":{"begin":93,"end":98},"obj":"SO:0000704"},{"id":"T650","span":{"begin":184,"end":188},"obj":"NCBITaxon:10088"},{"id":"T651","span":{"begin":202,"end":209},"obj":"SO:0000704"},{"id":"T652","span":{"begin":235,"end":240},"obj":"NCBITaxon:10088"},{"id":"T653","span":{"begin":278,"end":288},"obj":"UBERON:0000160"},{"id":"T654","span":{"begin":342,"end":351},"obj":"GO:0065007"},{"id":"T655","span":{"begin":393,"end":397},"obj":"PR:000001044"},{"id":"T656","span":{"begin":423,"end":433},"obj":"SO:0001024"},{"id":"T657","span":{"begin":441,"end":456},"obj":"SO:0005858"},{"id":"T658","span":{"begin":460,"end":465},"obj":"NCBITaxon:9606"},{"id":"T659","span":{"begin":584,"end":589},"obj":"NCBITaxon:10088"},{"id":"T660","span":{"begin":626,"end":630},"obj":"UBERON:0002048"},{"id":"T661","span":{"begin":659,"end":675},"obj":"CL:0000842"},{"id":"T662","span":{"begin":663,"end":670},"obj":"GO:0005634"},{"id":"T663","span":{"begin":676,"end":688},"obj":"UBERON:0005169"},{"id":"T664","span":{"begin":721,"end":726},"obj":"NCBITaxon:10088"},{"id":"T665","span":{"begin":727,"end":734},"obj":"UBERON:0001005"},{"id":"T666","span":{"begin":800,"end":806},"obj":"UBERON:0001005"}],"attributes":[{"subj":"T646","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T647","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T648","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T649","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T650","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T651","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T652","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T653","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T654","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T655","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T656","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T657","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T658","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T659","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T660","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T661","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T662","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T663","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T664","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T665","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T666","pred":"source","obj":"craft-ca-core-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#93ecc1","default":true},{"id":"craft-ca-core-ex-dev","color":"#eca793"},{"id":"craft-ca-core-dev","color":"#9398ec"}]}]}}