PMC:1166548 / 15104-16098 JSONTXT

{"project":"craft-sa-dev","denotations":[{"id":"T7419","span":{"begin":600,"end":605},"obj":"JJ"},{"id":"T7418","span":{"begin":596,"end":599},"obj":"CC"},{"id":"T7417","span":{"begin":593,"end":595},"obj":"NN"},{"id":"T7416","span":{"begin":606,"end":617},"obj":"NNS"},{"id":"T7415","span":{"begin":589,"end":592},"obj":"DT"},{"id":"T7414","span":{"begin":586,"end":588},"obj":"IN"},{"id":"T7413","span":{"begin":572,"end":585},"obj":"NNS"},{"id":"T7412","span":{"begin":567,"end":571},"obj":"NN"},{"id":"T7411","span":{"begin":558,"end":566},"obj":"VBG"},{"id":"T7410","span":{"begin":553,"end":557},"obj":"IN"},{"id":"T7409","span":{"begin":543,"end":552},"obj":"NN"},{"id":"T7408","span":{"begin":538,"end":542},"obj":"JJ"},{"id":"T7407","span":{"begin":535,"end":537},"obj":"IN"},{"id":"T7406","span":{"begin":525,"end":534},"obj":"NNS"},{"id":"T7405","span":{"begin":520,"end":524},"obj":"NN"},{"id":"T7404","span":{"begin":517,"end":519},"obj":"IN"},{"id":"T7403","span":{"begin":504,"end":516},"obj":"NN"},{"id":"T7375","span":{"begin":9,"end":21},"obj":"NN"},{"id":"T7376","span":{"begin":22,"end":24},"obj":"IN"},{"id":"T7377","span":{"begin":25,"end":29},"obj":"NN"},{"id":"T7378","span":{"begin":30,"end":39},"obj":"NNS"},{"id":"T7379","span":{"begin":40,"end":42},"obj":"IN"},{"id":"T7380","span":{"begin":43,"end":49},"obj":"JJ"},{"id":"T7381","span":{"begin":50,"end":59},"obj":"NN"},{"id":"T7382","span":{"begin":60,"end":64},"obj":"IN"},{"id":"T7383","span":{"begin":65,"end":73},"obj":"VBG"},{"id":"T7384","span":{"begin":74,"end":78},"obj":"NN"},{"id":"T7385","span":{"begin":79,"end":92},"obj":"NNS"},{"id":"T7386","span":{"begin":93,"end":95},"obj":"IN"},{"id":"T7387","span":{"begin":96,"end":99},"obj":"DT"},{"id":"T7388","span":{"begin":113,"end":124},"obj":"NNS"},{"id":"T7389","span":{"begin":100,"end":102},"obj":"NN"},{"id":"T7390","span":{"begin":103,"end":106},"obj":"CC"},{"id":"T7391","span":{"begin":107,"end":112},"obj":"JJ"},{"id":"T7392","span":{"begin":124,"end":125},"obj":"."},{"id":"T7420","span":{"begin":617,"end":618},"obj":"."},{"id":"T3569","span":{"begin":0,"end":994},"obj":"DT"}],"relations":[{"id":"R4990","pred":"prep","subj":"T7376","obj":"T7375"},{"id":"R4991","pred":"compound","subj":"T7377","obj":"T7378"},{"id":"R4992","pred":"pobj","subj":"T7378","obj":"T7376"},{"id":"R4993","pred":"prep","subj":"T7379","obj":"T7375"},{"id":"R4994","pred":"amod","subj":"T7380","obj":"T7381"},{"id":"R4995","pred":"pobj","subj":"T7381","obj":"T7379"},{"id":"R4996","pred":"prep","subj":"T7382","obj":"T7381"},{"id":"R4997","pred":"pcomp","subj":"T7383","obj":"T7382"},{"id":"R4998","pred":"compound","subj":"T7384","obj":"T7385"},{"id":"R4999","pred":"dobj","subj":"T7385","obj":"T7383"},{"id":"R5000","pred":"prep","subj":"T7386","obj":"T7383"},{"id":"R5001","pred":"det","subj":"T7387","obj":"T7388"},{"id":"R5002","pred":"pobj","subj":"T7388","obj":"T7386"},{"id":"R5003","pred":"nmod","subj":"T7389","obj":"T7388"},{"id":"R5004","pred":"cc","subj":"T7390","obj":"T7389"},{"id":"R5005","pred":"conj","subj":"T7391","obj":"T7389"},{"id":"R5006","pred":"punct","subj":"T7392","obj":"T7375"},{"id":"R5007","pred":"prep","subj":"T7404","obj":"T7403"},{"id":"R5008","pred":"compound","subj":"T7405","obj":"T7406"},{"id":"R5009","pred":"pobj","subj":"T7406","obj":"T7404"},{"id":"R5010","pred":"prep","subj":"T7407","obj":"T7403"},{"id":"R5011","pred":"amod","subj":"T7408","obj":"T7409"},{"id":"R5012","pred":"pobj","subj":"T7409","obj":"T7407"},{"id":"R5013","pred":"prep","subj":"T7410","obj":"T7409"},{"id":"R5014","pred":"pcomp","subj":"T7411","obj":"T7410"},{"id":"R5015","pred":"compound","subj":"T7412","obj":"T7413"},{"id":"R5016","pred":"dobj","subj":"T7413","obj":"T7411"},{"id":"R5017","pred":"prep","subj":"T7414","obj":"T7411"},{"id":"R5018","pred":"det","subj":"T7415","obj":"T7416"},{"id":"R5019","pred":"pobj","subj":"T7416","obj":"T7414"},{"id":"R5020","pred":"nmod","subj":"T7417","obj":"T7416"},{"id":"R5021","pred":"cc","subj":"T7418","obj":"T7417"},{"id":"R5022","pred":"conj","subj":"T7419","obj":"T7417"},{"id":"R5023","pred":"punct","subj":"T7420","obj":"T7403"}],"text":"Table 1 Distribution of Cftr genotypes in female offspring from breeding Cftr heterozygotes on the B6 and mixed backgrounds.\nB6 Background Mixed Background\nCftr Observed Expected Observed Expected\n+/+ 207 175 57 47\n+/- 371 350 88 94\n-/- 122 175 42 47\nP 0.00001 (0.04533)* 0.21724\nStatistical analysis was by Chi-square. (*) P-value if the sample size for the B6 mice is adjusted to be equal to that of the mixed background mice, assuming the same distribution of genotypes.\nTable 2 Distribution of Cftr genotypes in male offspring from breeding Cftr heterozygotes on the B6 and mixed backgrounds.\nB6 Background Mixed Background\nCftr Observed Expected Observed Expected\n+/+ 240 201 57 52\n+/- 431 403 115 104\n-/- 134 201 36 52\nP \u003c0.00001 (0.01612)* 0.03749\nStatistical analysis was by Chi-square. (*) P-value if the sample size for the B6 mice is adjusted to be equal to that of the mixed background mice, assuming the same distribution of genotypes. The"}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T7402","span":{"begin":567,"end":571},"obj":"PR_EXT:000001044"},{"id":"T7401","span":{"begin":558,"end":566},"obj":"GO_EXT:breeding"},{"id":"T7400","span":{"begin":538,"end":542},"obj":"PATO_UBERON_EXT:male_or_bearer_of_maleness"},{"id":"T7399","span":{"begin":525,"end":534},"obj":"SO_EXT:genotype_or_entity_with_genotype"},{"id":"T7398","span":{"begin":520,"end":524},"obj":"PR_EXT:000001044"},{"id":"T7370","span":{"begin":25,"end":29},"obj":"PR_EXT:000001044"},{"id":"T7371","span":{"begin":30,"end":39},"obj":"SO_EXT:genotype_or_entity_with_genotype"},{"id":"T7372","span":{"begin":43,"end":49},"obj":"PATO_UBERON_EXT:female_or_bearer_of_femaleness"},{"id":"T7373","span":{"begin":65,"end":73},"obj":"GO_EXT:breeding"},{"id":"T7374","span":{"begin":74,"end":78},"obj":"PR_EXT:000001044"}],"text":"Table 1 Distribution of Cftr genotypes in female offspring from breeding Cftr heterozygotes on the B6 and mixed backgrounds.\nB6 Background Mixed Background\nCftr Observed Expected Observed Expected\n+/+ 207 175 57 47\n+/- 371 350 88 94\n-/- 122 175 42 47\nP 0.00001 (0.04533)* 0.21724\nStatistical analysis was by Chi-square. (*) P-value if the sample size for the B6 mice is adjusted to be equal to that of the mixed background mice, assuming the same distribution of genotypes.\nTable 2 Distribution of Cftr genotypes in male offspring from breeding Cftr heterozygotes on the B6 and mixed backgrounds.\nB6 Background Mixed Background\nCftr Observed Expected Observed Expected\n+/+ 240 201 57 52\n+/- 431 403 115 104\n-/- 134 201 36 52\nP \u003c0.00001 (0.01612)* 0.03749\nStatistical analysis was by Chi-square. (*) P-value if the sample size for the B6 mice is adjusted to be equal to that of the mixed background mice, assuming the same distribution of genotypes. The"}

{"project":"craft-ca-core-dev","denotations":[{"id":"T7397","span":{"begin":567,"end":571},"obj":"PR:000001044"},{"id":"T7396","span":{"begin":520,"end":524},"obj":"PR:000001044"},{"id":"T7368","span":{"begin":25,"end":29},"obj":"PR:000001044"},{"id":"T7369","span":{"begin":74,"end":78},"obj":"PR:000001044"}],"text":"Table 1 Distribution of Cftr genotypes in female offspring from breeding Cftr heterozygotes on the B6 and mixed backgrounds.\nB6 Background Mixed Background\nCftr Observed Expected Observed Expected\n+/+ 207 175 57 47\n+/- 371 350 88 94\n-/- 122 175 42 47\nP 0.00001 (0.04533)* 0.21724\nStatistical analysis was by Chi-square. (*) P-value if the sample size for the B6 mice is adjusted to be equal to that of the mixed background mice, assuming the same distribution of genotypes.\nTable 2 Distribution of Cftr genotypes in male offspring from breeding Cftr heterozygotes on the B6 and mixed backgrounds.\nB6 Background Mixed Background\nCftr Observed Expected Observed Expected\n+/+ 240 201 57 52\n+/- 431 403 115 104\n-/- 134 201 36 52\nP \u003c0.00001 (0.01612)* 0.03749\nStatistical analysis was by Chi-square. (*) P-value if the sample size for the B6 mice is adjusted to be equal to that of the mixed background mice, assuming the same distribution of genotypes. The"}