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PMC:116589 / 7819-8663 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T2003 160-162 NN denotes ES
T2004 163-167 NN denotes cell
T2005 174-185 VBD denotes transmitted
T2006 186-193 IN denotes through
T2007 194-197 DT denotes the
T2008 198-206 NN denotes germline
T2009 206-208 , denotes ,
T2010 208-215 VBG denotes leading
T2011 216-218 IN denotes to
T2012 219-222 DT denotes the
T2013 223-236 NN denotes establishment
T2014 237-239 IN denotes of
T2015 239-241 , denotes ,
T2016 241-244 NN denotes CK4
T2017 245-249 NN denotes ECFP
T2018 244-245 HYPH denotes /
T2019 250-253 CC denotes and
T2020 254-257 NN denotes CK6
T2021 258-262 NN denotes ECFP
T2022 257-258 HYPH denotes /
T2023 262-264 , denotes ,
T2024 264-267 CD denotes two
T2025 268-275 NNS denotes strains
T2026 276-278 IN denotes of
T2027 279-283 NNS denotes mice
T2028 284-290 VBG denotes having
T2029 291-295 NN denotes cyan
T2030 308-315 NN denotes protein
T2031 296-307 JJ denotes fluorescent
T2032 316-326 NN denotes expression
T2033 327-330 CC denotes and
T2034 330-332 , denotes ,
T2035 332-335 NN denotes YC5
T2036 336-340 NN denotes EYFP
T2037 335-336 HYPH denotes /
T2038 341-344 CC denotes and
T2039 345-348 NN denotes 2A4
T2040 349-353 NN denotes EYFP
T2069 535-542 IN denotes through
T2070 543-559 NN denotes postimplantation
T2071 560-573 NN denotes embryogenesis
T2072 574-576 IN denotes to
T2073 577-586 NN denotes adulthood
T2074 587-588 -LRB- denotes (
T2075 588-592 NN denotes Fig.
T2076 593-594 CD denotes 2
T2077 594-595 -RRB- denotes )
T2078 595-596 . denotes .
T2079 596-689 sentence denotes One line expressing each color was chosen for further analysis and breeding to homozygosity.
T2080 597-600 CD denotes One
T2081 601-605 NN denotes line
T2082 632-638 VBN denotes chosen
T2083 606-616 VBG denotes expressing
T2084 617-621 DT denotes each
T2085 622-627 NN denotes color
T2086 628-631 VBD denotes was
T2087 639-642 IN denotes for
T2088 643-650 JJ denotes further
T2089 651-659 NN denotes analysis
T2090 660-663 CC denotes and
T2091 664-672 NN denotes breeding
T2092 673-675 IN denotes to
T2093 676-688 NN denotes homozygosity
T2094 688-689 . denotes .
T2095 689-844 sentence denotes The availability of homozygous animals demonstrated that both reporter gene expression and the site of transgene integration were developmentally neutral.
T2096 690-693 DT denotes The
T2097 694-706 NN denotes availability
T2098 729-741 VBD denotes demonstrated
T2099 707-709 IN denotes of
T2100 710-720 JJ denotes homozygous
T2101 721-728 NNS denotes animals
T2102 742-746 IN denotes that
T2103 815-819 VBD denotes were
T2104 747-751 CC denotes both
T2105 766-776 NN denotes expression
T2106 752-760 NN denotes reporter
T2107 761-765 NN denotes gene
T2108 777-780 CC denotes and
T2109 781-784 DT denotes the
T2110 785-789 NN denotes site
T2111 790-792 IN denotes of
T2112 793-802 NN denotes transgene
T2113 803-814 NN denotes integration
T2114 820-835 RB denotes developmentally
T2115 836-843 JJ denotes neutral
T2116 843-844 . denotes .
T1970 0-150 sentence denotes Two ECFP+ and two EYFP+ clones exhibiting robust fluorescence were used to generate chimeras through ES cell <-> morula stage embryo aggregation [13].
T1971 0-3 CD denotes Two
T1972 4-9 JJ denotes ECFP+
T1973 24-30 NNS denotes clones
T1974 10-13 CC denotes and
T1975 14-17 CD denotes two
T1976 18-23 JJ denotes EYFP+
T1977 67-71 VBN denotes used
T1978 31-41 VBG denotes exhibiting
T1979 42-48 JJ denotes robust
T1980 49-61 NN denotes fluorescence
T1981 62-66 VBD denotes were
T1982 72-74 TO denotes to
T1983 75-83 VB denotes generate
T1984 84-92 NNS denotes chimeras
T1985 93-100 IN denotes through
T1986 101-103 NN denotes ES
T1987 104-108 NN denotes cell
T1988 109-110 SYM denotes <
T1989 133-144 NN denotes aggregation
T1990 110-111 HYPH denotes -
T1991 111-112 SYM denotes >
T1992 113-119 NN denotes morula
T1993 120-125 NN denotes stage
T1994 126-132 NN denotes embryo
T1995 145-146 -LRB- denotes [
T1996 146-148 CD denotes 13
T1997 148-149 -RRB- denotes ]
T1998 149-150 . denotes .
T1999 150-423 sentence denotes All four ES cell lines transmitted through the germline, leading to the establishment of, CK4/ECFP and CK6/ECFP, two strains of mice having cyan fluorescent protein expression and, YC5/EYFP and 2A4/EYFP, two strains having widespread yellow fluorescent protein expression.
T2000 151-154 DT denotes All
T2001 168-173 NNS denotes lines
T2002 155-159 CD denotes four
T2041 348-349 HYPH denotes /
T2042 353-355 , denotes ,
T2043 355-358 CD denotes two
T2044 359-366 NNS denotes strains
T2045 367-373 VBG denotes having
T2046 374-384 JJ denotes widespread
T2047 412-422 NN denotes expression
T2048 385-391 JJ denotes yellow
T2049 404-411 NN denotes protein
T2050 392-403 JJ denotes fluorescent
T2051 422-423 . denotes .
T2052 423-596 sentence denotes In these mice the respective FP expression is constituitive, starting at preimplantation stages and continuing through postimplantation embryogenesis to adulthood (Fig. 2).
T2053 424-426 IN denotes In
T2054 467-469 VBZ denotes is
T2055 427-432 DT denotes these
T2056 433-437 NNS denotes mice
T2057 438-441 DT denotes the
T2058 456-466 NN denotes expression
T2059 442-452 JJ denotes respective
T2060 453-455 NN denotes FP
T2061 470-483 JJ denotes constituitive
T2062 483-485 , denotes ,
T2063 485-493 VBG denotes starting
T2064 494-496 IN denotes at
T2065 497-512 NN denotes preimplantation
T2066 513-519 NNS denotes stages
T2067 520-523 CC denotes and
T2068 524-534 VBG denotes continuing
R1280 T2014 T2013 prep of,establishment
R1281 T2015 T2014 punct ", ",of
R1282 T2016 T2017 compound CK4,ECFP
R1283 T2017 T2014 pobj ECFP,of
R1284 T2018 T2017 punct /,ECFP
R1285 T2019 T2017 cc and,ECFP
R1286 T2020 T2021 compound CK6,ECFP
R1287 T2021 T2017 conj ECFP,ECFP
R1288 T2022 T2021 punct /,ECFP
R1289 T2023 T2017 punct ", ",ECFP
R1290 T2024 T2025 nummod two,strains
R1291 T2025 T2017 appos strains,ECFP
R1292 T2026 T2025 prep of,strains
R1293 T2027 T2026 pobj mice,of
R1294 T2028 T2025 acl having,strains
R1295 T2029 T2030 nmod cyan,protein
R1296 T2030 T2032 compound protein,expression
R1297 T2031 T2030 amod fluorescent,protein
R1298 T2032 T2028 dobj expression,having
R1299 T2033 T2017 cc and,ECFP
R1300 T2034 T2017 punct ", ",ECFP
R1301 T2035 T2036 compound YC5,EYFP
R1302 T2036 T2017 conj EYFP,ECFP
R1303 T2037 T2036 punct /,EYFP
R1304 T2038 T2036 cc and,EYFP
R1305 T2039 T2040 compound 2A4,EYFP
R1306 T2040 T2036 conj EYFP,EYFP
R1307 T2041 T2040 punct /,EYFP
R1308 T2042 T2036 punct ", ",EYFP
R1309 T2043 T2044 nummod two,strains
R1310 T2044 T2036 appos strains,EYFP
R1311 T2045 T2044 acl having,strains
R1312 T2046 T2047 amod widespread,expression
R1313 T2047 T2045 dobj expression,having
R1314 T2048 T2049 amod yellow,protein
R1315 T2049 T2047 compound protein,expression
R1316 T2050 T2049 amod fluorescent,protein
R1317 T2051 T2005 punct .,transmitted
R1318 T2053 T2054 prep In,is
R1319 T2055 T2056 det these,mice
R1320 T2056 T2053 pobj mice,In
R1321 T2057 T2058 det the,expression
R1322 T2058 T2054 nsubj expression,is
R1323 T2059 T2058 amod respective,expression
R1324 T2060 T2058 compound FP,expression
R1325 T2061 T2054 acomp constituitive,is
R1326 T2062 T2054 punct ", ",is
R1327 T2063 T2054 advcl starting,is
R1328 T2064 T2063 prep at,starting
R1329 T2065 T2066 compound preimplantation,stages
R1330 T2066 T2064 pobj stages,at
R1331 T2067 T2063 cc and,starting
R1332 T2068 T2063 conj continuing,starting
R1333 T2069 T2068 prep through,continuing
R1334 T2070 T2071 compound postimplantation,embryogenesis
R1335 T2071 T2069 pobj embryogenesis,through
R1336 T2072 T2068 prep to,continuing
R1337 T2073 T2072 pobj adulthood,to
R1338 T2074 T2075 punct (,Fig.
R1339 T2075 T2054 parataxis Fig.,is
R1340 T2076 T2075 nummod 2,Fig.
R1341 T2077 T2075 punct ),Fig.
R1342 T2078 T2054 punct .,is
R1343 T2080 T2081 nummod One,line
R1344 T2081 T2082 nsubjpass line,chosen
R1345 T2083 T2081 acl expressing,line
R1346 T2084 T2085 det each,color
R1347 T2085 T2083 dobj color,expressing
R1348 T2086 T2082 auxpass was,chosen
R1349 T2087 T2082 prep for,chosen
R1350 T2088 T2089 amod further,analysis
R1351 T2089 T2087 pobj analysis,for
R1352 T2090 T2089 cc and,analysis
R1353 T2091 T2089 conj breeding,analysis
R1354 T2092 T2091 prep to,breeding
R1355 T2093 T2092 pobj homozygosity,to
R1356 T2094 T2082 punct .,chosen
R1357 T2096 T2097 det The,availability
R1358 T2097 T2098 nsubj availability,demonstrated
R1359 T2099 T2097 prep of,availability
R1360 T2100 T2101 amod homozygous,animals
R1361 T2101 T2099 pobj animals,of
R1263 T1995 T1996 punct [,13
R1240 T1971 T1972 advmod Two,ECFP+
R1241 T1972 T1973 amod ECFP+,clones
R1242 T1973 T1977 nsubjpass clones,used
R1243 T1974 T1972 cc and,ECFP+
R1244 T1975 T1976 advmod two,EYFP+
R1245 T1976 T1972 conj EYFP+,ECFP+
R1246 T1978 T1973 acl exhibiting,clones
R1247 T1979 T1980 amod robust,fluorescence
R1248 T1980 T1978 dobj fluorescence,exhibiting
R1249 T1981 T1977 auxpass were,used
R1250 T1982 T1983 aux to,generate
R1251 T1983 T1977 advcl generate,used
R1252 T1984 T1983 dobj chimeras,generate
R1253 T1985 T1983 prep through,generate
R1254 T1986 T1987 compound ES,cell
R1255 T1987 T1985 pobj cell,through
R1256 T1988 T1989 punct <,aggregation
R1257 T1989 T1987 prep aggregation,cell
R1258 T1990 T1989 punct -,aggregation
R1259 T1991 T1989 punct >,aggregation
R1260 T1992 T1993 compound morula,stage
R1261 T1993 T1989 compound stage,aggregation
R1262 T1994 T1989 compound embryo,aggregation
R1264 T1996 T1977 parataxis 13,used
R1265 T1997 T1996 punct ],13
R1266 T1998 T1977 punct .,used
R1267 T2000 T2001 det All,lines
R1268 T2001 T2005 nsubj lines,transmitted
R1269 T2002 T2001 nummod four,lines
R1270 T2003 T2001 compound ES,lines
R1271 T2004 T2001 compound cell,lines
R1272 T2006 T2005 prep through,transmitted
R1273 T2007 T2008 det the,germline
R1274 T2008 T2006 pobj germline,through
R1275 T2009 T2005 punct ", ",transmitted
R1276 T2010 T2005 advcl leading,transmitted
R1277 T2011 T2010 prep to,leading
R1278 T2012 T2013 det the,establishment
R1279 T2013 T2011 pobj establishment,to
R1362 T2102 T2103 mark that,were
R1363 T2103 T2098 ccomp were,demonstrated
R1364 T2104 T2105 preconj both,expression
R1365 T2105 T2103 nsubj expression,were
R1366 T2106 T2107 compound reporter,gene
R1367 T2107 T2105 compound gene,expression
R1368 T2108 T2105 cc and,expression
R1369 T2109 T2110 det the,site
R1370 T2110 T2105 conj site,expression
R1371 T2111 T2110 prep of,site
R1372 T2112 T2113 compound transgene,integration
R1373 T2113 T2111 pobj integration,of
R1374 T2114 T2115 advmod developmentally,neutral
R1375 T2115 T2103 acomp neutral,were
R1376 T2116 T2098 punct .,demonstrated

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T1313 24-30 SO_EXT:sequence_cloned_entity denotes clones
T1314 101-108 CL:0002322 denotes ES cell
T1315 104-108 CL_GO_EXT:cell denotes cell
T1316 113-119 UBERON:0000085 denotes morula
T1317 126-132 UBERON:0000922 denotes embryo
T1318 160-167 CL:0002322 denotes ES cell
T1319 163-167 CL_GO_EXT:cell denotes cell
T1320 279-283 NCBITaxon:10088 denotes mice
T1321 308-315 CHEBI_PR_EXT:protein denotes protein
T1322 316-326 GO:0010467 denotes expression
T1323 404-411 CHEBI_PR_EXT:protein denotes protein
T1324 412-422 GO:0010467 denotes expression
T1325 433-437 NCBITaxon:10088 denotes mice
T1326 456-466 GO:0010467 denotes expression
T1327 500-512 GO:0007566 denotes implantation
T1328 547-559 GO:0007566 denotes implantation
T1329 560-573 GO:0009790 denotes embryogenesis
T1330 577-586 UBERON:0000113 denotes adulthood
T1331 606-616 GO:0010467 denotes expressing
T1332 664-672 GO_EXT:breeding denotes breeding
T1333 721-728 NCBITaxon:33208 denotes animals
T1334 761-765 SO_EXT:0000704 denotes gene
T1335 761-776 GO:0010467 denotes gene expression
T1336 785-792 _FRAGMENT denotes site of
T1337 803-814 SO_EXT:0000366 denotes integration
T1338 793-802 SO_EXT:0000902 denotes transgene
R704 T1337 T1336 _lexicallyChainedTo integration,site of

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T1166 101-108 CL:0002322 denotes ES cell
T1167 113-119 UBERON:0000085 denotes morula
T1168 126-132 UBERON:0000922 denotes embryo
T1169 160-167 CL:0002322 denotes ES cell
T1170 279-283 NCBITaxon:10088 denotes mice
T1171 316-326 GO:0010467 denotes expression
T1172 412-422 GO:0010467 denotes expression
T1173 433-437 NCBITaxon:10088 denotes mice
T1174 456-466 GO:0010467 denotes expression
T1175 500-512 GO:0007566 denotes implantation
T1176 547-559 GO:0007566 denotes implantation
T1177 560-573 GO:0009790 denotes embryogenesis
T1178 577-586 UBERON:0000113 denotes adulthood
T1179 606-616 GO:0010467 denotes expressing
T1180 721-728 NCBITaxon:33208 denotes animals
T1181 761-765 SO:0000704 denotes gene
T1182 761-776 GO:0010467 denotes gene expression
T1183 785-792 _FRAGMENT denotes site of
T1184 803-814 SO:0000366 denotes integration
T1185 793-802 SO:0000902 denotes transgene
R702 T1184 T1183 _lexicallyChainedTo integration,site of

2_test

Id Subject Object Predicate Lexical cue
12079497-8361547-8577608 146-148 8361547 denotes 13