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PMC:116589 / 10822-11749 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T2224 0-4 RB denotes Even
T2225 45-51 VBD denotes failed
T2226 5-11 IN denotes though
T2227 12-15 PRP$ denotes our
T2228 39-44 NNS denotes lines
T2229 16-19 NN denotes RFP
T2230 20-30 JJ denotes transgenic
T2231 31-33 NN denotes ES
T2232 34-38 NN denotes cell
T2233 116-124 VBD denotes selected
T2234 52-54 TO denotes to
T2235 55-63 VB denotes maintain
T2236 64-70 JJ denotes strong
T2237 79-89 NN denotes expression
T2238 71-78 JJ denotes uniform
T2239 90-94 IN denotes with
T2240 95-97 FW denotes in
T2241 98-103 FW denotes vitro
T2242 104-111 NN denotes passage
T2243 111-113 , denotes ,
T2244 113-115 PRP denotes we
T2245 125-130 CD denotes three
T2246 131-136 NNS denotes lines
T2247 137-147 VBG denotes exhibiting
T2248 148-151 DT denotes the
T2249 164-174 NN denotes expression
T2250 152-156 RBS denotes most
T2251 157-163 JJ denotes robust
T2252 175-178 IN denotes for
T2253 179-185 VBG denotes making
T2254 186-194 NNS denotes chimeras
T2255 194-196 , denotes ,
T2256 196-198 IN denotes in
T2257 199-204 NN denotes order
T2258 205-207 TO denotes to
T2259 208-217 VB denotes ascertain
T2260 218-225 IN denotes whether
T2261 235-242 VB denotes achieve
T2262 226-228 PRP denotes we
T2263 229-234 MD denotes could
T2264 242-244 , denotes ,
T2265 244-246 CC denotes or
T2266 247-255 RB denotes possibly
T2267 256-263 VB denotes recover
T2268 263-265 , denotes ,
T2269 265-268 NN denotes RFP
T2270 269-279 NN denotes expression
T2271 280-282 IN denotes in
T2272 283-290 NNS denotes animals
T2273 290-291 . denotes .
T2274 291-371 sentence denotes Cells were flow sorted prior to aggregation so as to enrich for RFP expression.
T2275 292-297 NNS denotes Cells
T2276 308-314 VBN denotes sorted
T2277 298-302 VBD denotes were
T2278 303-307 NN denotes flow
T2279 315-320 RB denotes prior
T2280 321-323 IN denotes to
T2281 324-335 NN denotes aggregation
T2282 336-338 RB denotes so
T2283 345-351 VB denotes enrich
T2284 339-341 IN denotes as
T2285 342-344 TO denotes to
T2286 352-355 IN denotes for
T2287 356-359 NN denotes RFP
T2288 360-370 NN denotes expression
T2289 370-371 . denotes .
T2290 371-556 sentence denotes Even though they had lost their characteristic ES cell morphology all three RFP+ ES cell lines went gemline as detected by coat color and PCR for the DsRed1 transgene (data not shown).
T2291 372-376 RB denotes Even
T2292 393-397 VBN denotes lost
T2293 377-383 IN denotes though
T2294 384-388 PRP denotes they
T2295 389-392 VBD denotes had
T2296 467-471 VBD denotes went
T2297 398-403 PRP$ denotes their
T2298 427-437 NN denotes morphology
T2299 404-418 JJ denotes characteristic
T2300 419-421 NN denotes ES
T2301 422-426 NN denotes cell
T2302 438-441 DT denotes all
T2303 461-466 NNS denotes lines
T2304 442-447 CD denotes three
T2305 448-452 JJ denotes RFP+
T2306 453-455 NN denotes ES
T2307 456-460 NN denotes cell
T2308 472-479 RB denotes gemline
T2309 480-482 IN denotes as
T2310 483-491 VBN denotes detected
T2311 492-494 IN denotes by
T2312 495-499 NN denotes coat
T2313 500-505 NN denotes color
T2314 506-509 CC denotes and
T2315 510-513 NN denotes PCR
T2316 514-517 IN denotes for
T2317 518-521 DT denotes the
T2318 529-538 NN denotes transgene
T2319 522-528 NN denotes DsRed1
T2320 539-540 -LRB- denotes (
T2321 549-554 VBN denotes shown
T2322 540-544 NNS denotes data
T2323 545-548 RB denotes not
T2324 554-555 -RRB- denotes )
T2325 555-556 . denotes .
T2326 556-677 sentence denotes However expression of the RFP reporter could not be detected in any organ of adult mice nor in embryos (data not shown).
T2327 557-564 RB denotes However
T2328 609-617 VBN denotes detected
T2329 565-575 NN denotes expression
T2330 576-578 IN denotes of
T2331 579-582 DT denotes the
T2332 587-595 NN denotes reporter
T2333 583-586 NN denotes RFP
T2334 596-601 MD denotes could
T2335 602-605 RB denotes not
T2336 606-608 VB denotes be
T2337 618-620 IN denotes in
T2338 621-624 DT denotes any
T2339 625-630 NN denotes organ
T2340 631-633 IN denotes of
T2341 634-639 JJ denotes adult
T2342 640-644 NNS denotes mice
T2343 645-648 CC denotes nor
T2344 649-651 IN denotes in
T2345 652-659 NNS denotes embryos
T2346 660-661 -LRB- denotes (
T2347 670-675 VBN denotes shown
T2348 661-665 NNS denotes data
T2349 666-669 RB denotes not
T2350 675-676 -RRB- denotes )
T2351 676-677 . denotes .
T2352 677-817 sentence denotes This suggests that the DsRed1 RFP reporter was unable to recapitulate the expression profile of the promoter/enhancer combination employed.
T2353 678-682 DT denotes This
T2354 683-691 VBZ denotes suggests
T2355 692-696 IN denotes that
T2356 721-724 VBD denotes was
T2357 697-700 DT denotes the
T2358 712-720 NN denotes reporter
T2359 701-707 NN denotes DsRed1
T2360 708-711 NN denotes RFP
T2361 725-731 JJ denotes unable
T2362 732-734 TO denotes to
T2363 735-747 VB denotes recapitulate
T2364 748-751 DT denotes the
T2365 763-770 NN denotes profile
T2366 752-762 NN denotes expression
T2367 771-773 IN denotes of
T2368 774-777 DT denotes the
T2369 796-807 NN denotes combination
T2370 778-786 NN denotes promoter
T2371 787-795 NN denotes enhancer
T2372 786-787 HYPH denotes /
T2373 808-816 VBN denotes employed
T2374 816-817 . denotes .
T2375 817-927 sentence denotes Therefore it appears that GFP variant reporters are more versatile with respect to their application in mice.
T2376 818-827 RB denotes Therefore
T2377 831-838 VBZ denotes appears
T2378 828-830 PRP denotes it
T2379 839-843 IN denotes that
T2380 866-869 VBP denotes are
T2381 844-847 NN denotes GFP
T2382 856-865 NNS denotes reporters
T2383 848-855 JJ denotes variant
T2384 870-874 RBR denotes more
T2385 875-884 JJ denotes versatile
T2386 885-889 IN denotes with
T2387 890-897 NN denotes respect
T2388 898-900 IN denotes to
T2389 901-906 PRP$ denotes their
T2390 907-918 NN denotes application
T2391 919-921 IN denotes in
T2392 922-926 NNS denotes mice
T2393 926-927 . denotes .
R1476 T2224 T2225 advmod Even,failed
R1477 T2225 T2233 advcl failed,selected
R1478 T2226 T2225 mark though,failed
R1479 T2227 T2228 poss our,lines
R1480 T2291 T2292 advmod Even,lost
R1481 T2228 T2225 nsubj lines,failed
R1482 T2292 T2296 advcl lost,went
R1483 T2293 T2292 mark though,lost
R1484 T2229 T2228 nmod RFP,lines
R1485 T2294 T2292 nsubj they,lost
R1486 T2295 T2292 aux had,lost
R1487 T2297 T2298 poss their,morphology
R1488 T2230 T2228 amod transgenic,lines
R1489 T2298 T2292 dobj morphology,lost
R1490 T2299 T2298 amod characteristic,morphology
R1491 T2300 T2301 compound ES,cell
R1492 T2301 T2298 compound cell,morphology
R1493 T2231 T2232 compound ES,cell
R1494 T2302 T2303 det all,lines
R1495 T2303 T2296 nsubj lines,went
R1496 T2304 T2303 nummod three,lines
R1497 T2232 T2228 compound cell,lines
R1498 T2305 T2303 amod RFP+,lines
R1499 T2306 T2307 compound ES,cell
R1500 T2234 T2235 aux to,maintain
R1501 T2307 T2303 compound cell,lines
R1502 T2308 T2296 advmod gemline,went
R1503 T2309 T2310 mark as,detected
R1504 T2310 T2296 advcl detected,went
R1505 T2235 T2225 xcomp maintain,failed
R1506 T2311 T2310 prep by,detected
R1507 T2312 T2313 compound coat,color
R1508 T2236 T2237 amod strong,expression
R1509 T2313 T2311 pobj color,by
R1510 T2314 T2313 cc and,color
R1511 T2315 T2313 conj PCR,color
R1512 T2237 T2235 dobj expression,maintain
R1513 T2316 T2315 prep for,PCR
R1514 T2317 T2318 det the,transgene
R1515 T2318 T2316 pobj transgene,for
R1516 T2238 T2237 amod uniform,expression
R1517 T2319 T2318 compound DsRed1,transgene
R1518 T2320 T2321 punct (,shown
R1519 T2321 T2296 parataxis shown,went
R1520 T2239 T2235 prep with,maintain
R1521 T2322 T2321 nsubj data,shown
R1522 T2323 T2321 neg not,shown
R1523 T2324 T2321 punct ),shown
R1524 T2240 T2241 advmod in,vitro
R1525 T2325 T2296 punct .,went
R1526 T2327 T2328 advmod However,detected
R1527 T2241 T2242 amod vitro,passage
R1528 T2329 T2328 nsubjpass expression,detected
R1529 T2242 T2239 pobj passage,with
R1530 T2330 T2329 prep of,expression
R1531 T2331 T2332 det the,reporter
R1532 T2332 T2330 pobj reporter,of
R1533 T2243 T2233 punct ", ",selected
R1534 T2333 T2332 compound RFP,reporter
R1535 T2334 T2328 aux could,detected
R1536 T2335 T2328 neg not,detected
R1537 T2244 T2233 nsubj we,selected
R1538 T2336 T2328 auxpass be,detected
R1539 T2337 T2328 prep in,detected
R1540 T2338 T2339 det any,organ
R1541 T2339 T2337 pobj organ,in
R1542 T2340 T2339 prep of,organ
R1543 T2245 T2246 nummod three,lines
R1544 T2341 T2342 amod adult,mice
R1545 T2246 T2233 dobj lines,selected
R1546 T2342 T2340 pobj mice,of
R1547 T2343 T2337 cc nor,in
R1548 T2247 T2246 acl exhibiting,lines
R1549 T2344 T2337 conj in,in
R1550 T2345 T2344 pobj embryos,in
R1551 T2248 T2249 det the,expression
R1552 T2346 T2347 punct (,shown
R1553 T2347 T2328 parataxis shown,detected
R1554 T2249 T2247 dobj expression,exhibiting
R1555 T2348 T2347 nsubj data,shown
R1556 T2349 T2347 neg not,shown
R1557 T2350 T2347 punct ),shown
R1558 T2250 T2251 advmod most,robust
R1559 T2351 T2328 punct .,detected
R1560 T2251 T2249 amod robust,expression
R1561 T2353 T2354 nsubj This,suggests
R1562 T2252 T2249 prep for,expression
R1563 T2355 T2356 mark that,was
R1564 T2356 T2354 ccomp was,suggests
R1565 T2253 T2252 pcomp making,for
R1566 T2357 T2358 det the,reporter
R1567 T2358 T2356 nsubj reporter,was
R1568 T2359 T2358 compound DsRed1,reporter
R1569 T2254 T2253 dobj chimeras,making
R1570 T2360 T2358 compound RFP,reporter
R1571 T2361 T2356 acomp unable,was
R1572 T2362 T2363 aux to,recapitulate
R1573 T2255 T2233 punct ", ",selected
R1574 T2363 T2361 xcomp recapitulate,unable
R1575 T2364 T2365 det the,profile
R1576 T2365 T2363 dobj profile,recapitulate
R1577 T2256 T2233 prep in,selected
R1578 T2366 T2365 compound expression,profile
R1579 T2367 T2365 prep of,profile
R1580 T2368 T2369 det the,combination
R1581 T2257 T2256 pobj order,in
R1582 T2369 T2367 pobj combination,of
R1583 T2370 T2371 compound promoter,enhancer
R1584 T2371 T2369 compound enhancer,combination
R1585 T2258 T2259 aux to,ascertain
R1586 T2372 T2371 punct /,enhancer
R1587 T2373 T2369 acl employed,combination
R1588 T2259 T2257 acl ascertain,order
R1589 T2374 T2354 punct .,suggests
R1590 T2376 T2377 advmod Therefore,appears
R1591 T2378 T2377 nsubj it,appears
R1592 T2379 T2380 mark that,are
R1593 T2380 T2377 ccomp are,appears
R1594 T2260 T2261 mark whether,achieve
R1595 T2381 T2382 nmod GFP,reporters
R1596 T2382 T2380 nsubj reporters,are
R1597 T2261 T2259 ccomp achieve,ascertain
R1598 T2383 T2381 amod variant,GFP
R1599 T2384 T2385 advmod more,versatile
R1600 T2385 T2380 acomp versatile,are
R1601 T2262 T2261 nsubj we,achieve
R1602 T2386 T2380 prep with,are
R1603 T2387 T2386 pobj respect,with
R1604 T2388 T2387 prep to,respect
R1605 T2389 T2390 poss their,application
R1606 T2263 T2261 aux could,achieve
R1607 T2390 T2388 pobj application,to
R1608 T2391 T2390 prep in,application
R1609 T2392 T2391 pobj mice,in
R1610 T2264 T2261 punct ", ",achieve
R1611 T2393 T2377 punct .,appears
R1612 T2265 T2261 cc or,achieve
R1614 T2266 T2267 advmod possibly,recover
R1615 T2267 T2261 conj recover,achieve
R1616 T2268 T2261 punct ", ",achieve
R1618 T2269 T2270 compound RFP,expression
R1622 T2270 T2261 dobj expression,achieve
R1626 T2271 T2261 prep in,achieve
R1629 T2272 T2271 pobj animals,in
R1634 T2273 T2233 punct .,selected
R1637 T2275 T2276 nsubjpass Cells,sorted
R1641 T2277 T2276 auxpass were,sorted
R1644 T2278 T2276 dep flow,sorted
R1648 T2279 T2276 advmod prior,sorted
R1650 T2280 T2279 prep to,prior
R1653 T2281 T2280 pobj aggregation,to
R1656 T2282 T2283 advmod so,enrich
R1661 T2283 T2276 advcl enrich,sorted
R1662 T2284 T2283 mark as,enrich
R1665 T2285 T2283 aux to,enrich
R1668 T2286 T2283 prep for,enrich
R1672 T2287 T2288 compound RFP,expression
R1676 T2288 T2286 pobj expression,for
R1680 T2289 T2276 punct .,sorted

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T1368 634-639 UBERON:0007023 denotes adult
T1369 640-644 NCBITaxon:10088 denotes mice
T1370 652-659 UBERON:0000922 denotes embryos
T1371 752-762 GO:0010467 denotes expression
T1372 778-786 SO_EXT:0000167 denotes promoter
T1373 787-795 SO_EXT:0000165 denotes enhancer
T1374 848-855 SO_EXT:sequence_variant_or_variation denotes variant
T1375 922-926 NCBITaxon:10088 denotes mice
T1351 20-30 SO_EXT:transgenic_entity denotes transgenic
T1352 31-38 CL:0002322 denotes ES cell
T1353 34-38 CL_GO_EXT:cell denotes cell
T1354 79-89 GO:0010467 denotes expression
T1355 164-174 GO:0010467 denotes expression
T1356 269-279 GO:0010467 denotes expression
T1357 283-290 NCBITaxon:33208 denotes animals
T1358 292-297 CL_GO_EXT:cell denotes Cells
T1359 360-370 GO:0010467 denotes expression
T1360 419-426 CL:0002322 denotes ES cell
T1361 422-426 CL_GO_EXT:cell denotes cell
T1362 453-460 CL:0002322 denotes ES cell
T1363 456-460 CL_GO_EXT:cell denotes cell
T1364 495-499 UBERON:0010166 denotes coat
T1365 529-538 SO_EXT:0000902 denotes transgene
T1366 565-575 GO:0010467 denotes expression
T1367 625-630 UBERON:0000062 denotes organ

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T1197 31-38 CL:0002322 denotes ES cell
T1198 79-89 GO:0010467 denotes expression
T1199 164-174 GO:0010467 denotes expression
T1200 269-279 GO:0010467 denotes expression
T1201 283-290 NCBITaxon:33208 denotes animals
T1202 360-370 GO:0010467 denotes expression
T1203 419-426 CL:0002322 denotes ES cell
T1204 453-460 CL:0002322 denotes ES cell
T1205 495-499 UBERON:0010166 denotes coat
T1206 529-538 SO:0000902 denotes transgene
T1207 565-575 GO:0010467 denotes expression
T1208 625-630 UBERON:0000062 denotes organ
T1209 634-639 UBERON:0007023 denotes adult
T1210 640-644 NCBITaxon:10088 denotes mice
T1211 652-659 UBERON:0000922 denotes embryos
T1212 752-762 GO:0010467 denotes expression
T1213 778-786 SO:0000167 denotes promoter
T1214 787-795 SO:0000165 denotes enhancer
T1215 922-926 NCBITaxon:10088 denotes mice