| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T4079 |
0-7 |
DT |
denotes |
Another |
| T4080 |
20-29 |
NN |
denotes |
phenotype |
| T4081 |
8-19 |
JJ |
denotes |
interesting |
| T4082 |
64-67 |
VBD |
denotes |
was |
| T4083 |
30-38 |
VBN |
denotes |
observed |
| T4084 |
39-41 |
IN |
denotes |
in |
| T4085 |
42-48 |
NN |
denotes |
ADAM22 |
| T4086 |
49-58 |
JJ |
denotes |
deficient |
| T4087 |
48-49 |
HYPH |
denotes |
- |
| T4088 |
59-63 |
NNS |
denotes |
mice |
| T4089 |
68-86 |
NN |
denotes |
hypomyelinogenesis |
| T4090 |
86-87 |
. |
denotes |
. |
| T4091 |
87-184 |
sentence |
denotes |
Histopathological analysis revealed marked hypomyelination in the sciatic and trigeminal nerves. |
| T4092 |
88-105 |
JJ |
denotes |
Histopathological |
| T4093 |
106-114 |
NN |
denotes |
analysis |
| T4094 |
115-123 |
VBD |
denotes |
revealed |
| T4095 |
124-130 |
JJ |
denotes |
marked |
| T4096 |
131-146 |
NN |
denotes |
hypomyelination |
| T4097 |
147-149 |
IN |
denotes |
in |
| T4098 |
150-153 |
DT |
denotes |
the |
| T4099 |
177-183 |
NNS |
denotes |
nerves |
| T4100 |
154-161 |
JJ |
denotes |
sciatic |
| T4101 |
162-165 |
CC |
denotes |
and |
| T4102 |
166-176 |
JJ |
denotes |
trigeminal |
| T4103 |
183-184 |
. |
denotes |
. |
| T4104 |
184-255 |
sentence |
denotes |
However, myelin formation in the spinal cord and the brain was normal. |
| T4105 |
185-192 |
RB |
denotes |
However |
| T4106 |
244-247 |
VBD |
denotes |
was |
| T4107 |
192-194 |
, |
denotes |
, |
| T4108 |
194-200 |
NN |
denotes |
myelin |
| T4109 |
201-210 |
NN |
denotes |
formation |
| T4110 |
211-213 |
IN |
denotes |
in |
| T4111 |
214-217 |
DT |
denotes |
the |
| T4112 |
225-229 |
NN |
denotes |
cord |
| T4113 |
218-224 |
JJ |
denotes |
spinal |
| T4114 |
230-233 |
CC |
denotes |
and |
| T4115 |
234-237 |
DT |
denotes |
the |
| T4116 |
238-243 |
NN |
denotes |
brain |
| T4117 |
248-254 |
JJ |
denotes |
normal |
| T4118 |
254-255 |
. |
denotes |
. |
| T4119 |
255-410 |
sentence |
denotes |
It was therefore evident that hypomyelinogenesis occurred specifically in the peripheral nerves in the knockout mice, suggesting Schwann cell dysfunction. |
| T4120 |
256-258 |
PRP |
denotes |
It |
| T4121 |
259-262 |
VBD |
denotes |
was |
| T4122 |
263-272 |
RB |
denotes |
therefore |
| T4123 |
273-280 |
JJ |
denotes |
evident |
| T4124 |
281-285 |
IN |
denotes |
that |
| T4125 |
305-313 |
VBD |
denotes |
occurred |
| T4126 |
286-304 |
NN |
denotes |
hypomyelinogenesis |
| T4127 |
314-326 |
RB |
denotes |
specifically |
| T4128 |
327-329 |
IN |
denotes |
in |
| T4129 |
330-333 |
DT |
denotes |
the |
| T4130 |
345-351 |
NNS |
denotes |
nerves |
| T4131 |
334-344 |
JJ |
denotes |
peripheral |
| T4132 |
352-354 |
IN |
denotes |
in |
| T4133 |
355-358 |
DT |
denotes |
the |
| T4134 |
368-372 |
NNS |
denotes |
mice |
| T4135 |
359-367 |
NN |
denotes |
knockout |
| T4136 |
372-374 |
, |
denotes |
, |
| T4137 |
374-384 |
VBG |
denotes |
suggesting |
| T4138 |
385-392 |
NNP |
denotes |
Schwann |
| T4139 |
393-397 |
NN |
denotes |
cell |
| T4140 |
398-409 |
NN |
denotes |
dysfunction |
| T4141 |
409-410 |
. |
denotes |
. |
| T4142 |
410-567 |
sentence |
denotes |
In the mutant sciatic nerve, the density of pro-myelinating Schwann cells (S100-positive, MBP-negative) was markedly higher than that seen in heterozygotes. |
| T4143 |
411-413 |
IN |
denotes |
In |
| T4144 |
515-518 |
VBD |
denotes |
was |
| T4145 |
414-417 |
DT |
denotes |
the |
| T4146 |
433-438 |
NN |
denotes |
nerve |
| T4147 |
418-424 |
NN |
denotes |
mutant |
| T4148 |
425-432 |
JJ |
denotes |
sciatic |
| T4149 |
438-440 |
, |
denotes |
, |
| T4150 |
440-443 |
DT |
denotes |
the |
| T4151 |
444-451 |
NN |
denotes |
density |
| T4152 |
452-454 |
IN |
denotes |
of |
| T4153 |
455-470 |
VBG |
denotes |
pro-myelinating |
| T4154 |
479-484 |
NNS |
denotes |
cells |
| T4155 |
471-478 |
NNP |
denotes |
Schwann |
| T4156 |
485-486 |
-LRB- |
denotes |
( |
| T4157 |
505-513 |
JJ |
denotes |
negative |
| T4158 |
486-490 |
NN |
denotes |
S100 |
| T4159 |
491-499 |
JJ |
denotes |
positive |
| T4160 |
490-491 |
HYPH |
denotes |
- |
| T4161 |
499-501 |
, |
denotes |
, |
| T4162 |
501-504 |
NN |
denotes |
MBP |
| T4163 |
504-505 |
HYPH |
denotes |
- |
| T4164 |
513-514 |
-RRB- |
denotes |
) |
| T4165 |
519-527 |
RB |
denotes |
markedly |
| T4166 |
528-534 |
JJR |
denotes |
higher |
| T4167 |
535-539 |
IN |
denotes |
than |
| T4168 |
540-544 |
DT |
denotes |
that |
| T4169 |
545-549 |
VBN |
denotes |
seen |
| T4170 |
550-552 |
IN |
denotes |
in |
| T4171 |
553-566 |
NNS |
denotes |
heterozygotes |
| T4172 |
566-567 |
. |
denotes |
. |
| T4173 |
567-752 |
sentence |
denotes |
Higher pro-myelinating Schwann cell density and marked delay in myelin formation indicate that ADAM22 plays an important role in Schwann cell differentiation, but not in proliferation. |
| T4174 |
568-574 |
JJR |
denotes |
Higher |
| T4175 |
604-611 |
NN |
denotes |
density |
| T4176 |
575-590 |
VBG |
denotes |
pro-myelinating |
| T4177 |
599-603 |
NN |
denotes |
cell |
| T4178 |
591-598 |
NNP |
denotes |
Schwann |
| T4179 |
649-657 |
VBP |
denotes |
indicate |
| T4180 |
612-615 |
CC |
denotes |
and |
| T4181 |
616-622 |
JJ |
denotes |
marked |
| T4182 |
623-628 |
NN |
denotes |
delay |
| T4183 |
629-631 |
IN |
denotes |
in |
| T4184 |
632-638 |
NN |
denotes |
myelin |
| T4185 |
639-648 |
NN |
denotes |
formation |
| T4186 |
658-662 |
IN |
denotes |
that |
| T4187 |
670-675 |
VBZ |
denotes |
plays |
| T4188 |
663-669 |
NN |
denotes |
ADAM22 |
| T4189 |
676-678 |
DT |
denotes |
an |
| T4190 |
689-693 |
NN |
denotes |
role |
| T4191 |
679-688 |
JJ |
denotes |
important |
| T4192 |
694-696 |
IN |
denotes |
in |
| T4193 |
697-704 |
NNP |
denotes |
Schwann |
| T4194 |
705-709 |
NN |
denotes |
cell |
| T4195 |
710-725 |
NN |
denotes |
differentiation |
| T4196 |
725-727 |
, |
denotes |
, |
| T4197 |
727-730 |
CC |
denotes |
but |
| T4198 |
731-734 |
RB |
denotes |
not |
| T4199 |
735-737 |
IN |
denotes |
in |
| T4200 |
738-751 |
NN |
denotes |
proliferation |
| T4201 |
751-752 |
. |
denotes |
. |
| R2463 |
T4079 |
T4080 |
det |
Another,phenotype |
| R2464 |
T4080 |
T4082 |
nsubj |
phenotype,was |
| R2465 |
T4081 |
T4080 |
amod |
interesting,phenotype |
| R2466 |
T4083 |
T4080 |
acl |
observed,phenotype |
| R2467 |
T4084 |
T4083 |
prep |
in,observed |
| R2468 |
T4085 |
T4086 |
npadvmod |
ADAM22,deficient |
| R2469 |
T4086 |
T4088 |
amod |
deficient,mice |
| R2470 |
T4087 |
T4086 |
punct |
-,deficient |
| R2471 |
T4088 |
T4084 |
pobj |
mice,in |
| R2472 |
T4089 |
T4082 |
attr |
hypomyelinogenesis,was |
| R2473 |
T4090 |
T4082 |
punct |
.,was |
| R2474 |
T4092 |
T4093 |
amod |
Histopathological,analysis |
| R2475 |
T4093 |
T4094 |
nsubj |
analysis,revealed |
| R2476 |
T4095 |
T4096 |
amod |
marked,hypomyelination |
| R2477 |
T4096 |
T4094 |
dobj |
hypomyelination,revealed |
| R2478 |
T4097 |
T4094 |
prep |
in,revealed |
| R2479 |
T4098 |
T4099 |
det |
the,nerves |
| R2480 |
T4099 |
T4097 |
pobj |
nerves,in |
| R2481 |
T4100 |
T4099 |
amod |
sciatic,nerves |
| R2482 |
T4101 |
T4100 |
cc |
and,sciatic |
| R2483 |
T4102 |
T4100 |
conj |
trigeminal,sciatic |
| R2484 |
T4103 |
T4094 |
punct |
.,revealed |
| R2485 |
T4105 |
T4106 |
advmod |
However,was |
| R2486 |
T4107 |
T4106 |
punct |
", ",was |
| R2487 |
T4108 |
T4109 |
compound |
myelin,formation |
| R2488 |
T4109 |
T4106 |
nsubj |
formation,was |
| R2489 |
T4110 |
T4109 |
prep |
in,formation |
| R2490 |
T4111 |
T4112 |
det |
the,cord |
| R2491 |
T4112 |
T4110 |
pobj |
cord,in |
| R2492 |
T4113 |
T4112 |
amod |
spinal,cord |
| R2493 |
T4114 |
T4112 |
cc |
and,cord |
| R2494 |
T4115 |
T4116 |
det |
the,brain |
| R2495 |
T4116 |
T4112 |
conj |
brain,cord |
| R2496 |
T4117 |
T4106 |
acomp |
normal,was |
| R2497 |
T4118 |
T4106 |
punct |
.,was |
| R2498 |
T4120 |
T4121 |
nsubj |
It,was |
| R2499 |
T4122 |
T4121 |
advmod |
therefore,was |
| R2500 |
T4123 |
T4121 |
acomp |
evident,was |
| R2501 |
T4124 |
T4125 |
mark |
that,occurred |
| R2502 |
T4125 |
T4121 |
ccomp |
occurred,was |
| R2503 |
T4126 |
T4125 |
nsubj |
hypomyelinogenesis,occurred |
| R2504 |
T4127 |
T4128 |
advmod |
specifically,in |
| R2505 |
T4128 |
T4125 |
prep |
in,occurred |
| R2506 |
T4129 |
T4130 |
det |
the,nerves |
| R2507 |
T4130 |
T4128 |
pobj |
nerves,in |
| R2508 |
T4131 |
T4130 |
amod |
peripheral,nerves |
| R2509 |
T4132 |
T4125 |
prep |
in,occurred |
| R2510 |
T4133 |
T4134 |
det |
the,mice |
| R2511 |
T4134 |
T4132 |
pobj |
mice,in |
| R2512 |
T4135 |
T4134 |
compound |
knockout,mice |
| R2513 |
T4136 |
T4125 |
punct |
", ",occurred |
| R2514 |
T4137 |
T4125 |
advcl |
suggesting,occurred |
| R2515 |
T4138 |
T4139 |
compound |
Schwann,cell |
| R2516 |
T4139 |
T4140 |
compound |
cell,dysfunction |
| R2517 |
T4140 |
T4137 |
dobj |
dysfunction,suggesting |
| R2518 |
T4141 |
T4121 |
punct |
.,was |
| R2519 |
T4143 |
T4144 |
prep |
In,was |
| R2520 |
T4145 |
T4146 |
det |
the,nerve |
| R2521 |
T4146 |
T4143 |
pobj |
nerve,In |
| R2522 |
T4147 |
T4146 |
nmod |
mutant,nerve |
| R2523 |
T4148 |
T4146 |
amod |
sciatic,nerve |
| R2524 |
T4149 |
T4144 |
punct |
", ",was |
| R2525 |
T4150 |
T4151 |
det |
the,density |
| R2526 |
T4151 |
T4144 |
nsubj |
density,was |
| R2527 |
T4152 |
T4151 |
prep |
of,density |
| R2528 |
T4153 |
T4154 |
amod |
pro-myelinating,cells |
| R2529 |
T4154 |
T4152 |
pobj |
cells,of |
| R2530 |
T4155 |
T4154 |
compound |
Schwann,cells |
| R2531 |
T4156 |
T4157 |
punct |
(,negative |
| R2532 |
T4157 |
T4154 |
parataxis |
negative,cells |
| R2533 |
T4158 |
T4159 |
npadvmod |
S100,positive |
| R2534 |
T4159 |
T4157 |
amod |
positive,negative |
| R2535 |
T4160 |
T4159 |
punct |
-,positive |
| R2536 |
T4161 |
T4157 |
punct |
", ",negative |
| R2537 |
T4162 |
T4157 |
npadvmod |
MBP,negative |
| R2538 |
T4163 |
T4157 |
punct |
-,negative |
| R2539 |
T4164 |
T4157 |
punct |
),negative |
| R2540 |
T4165 |
T4166 |
advmod |
markedly,higher |
| R2541 |
T4166 |
T4144 |
acomp |
higher,was |
| R2542 |
T4167 |
T4166 |
prep |
than,higher |
| R2543 |
T4168 |
T4167 |
pobj |
that,than |
| R2544 |
T4169 |
T4168 |
acl |
seen,that |
| R2545 |
T4170 |
T4169 |
prep |
in,seen |
| R2546 |
T4171 |
T4170 |
pobj |
heterozygotes,in |
| R2547 |
T4172 |
T4144 |
punct |
.,was |
| R2548 |
T4174 |
T4175 |
amod |
Higher,density |
| R2549 |
T4175 |
T4179 |
nsubj |
density,indicate |
| R2550 |
T4176 |
T4177 |
amod |
pro-myelinating,cell |
| R2551 |
T4177 |
T4175 |
compound |
cell,density |
| R2552 |
T4178 |
T4177 |
compound |
Schwann,cell |
| R2553 |
T4180 |
T4175 |
cc |
and,density |
| R2554 |
T4181 |
T4182 |
amod |
marked,delay |
| R2555 |
T4182 |
T4175 |
conj |
delay,density |
| R2556 |
T4183 |
T4182 |
prep |
in,delay |
| R2557 |
T4184 |
T4185 |
compound |
myelin,formation |
| R2558 |
T4185 |
T4183 |
pobj |
formation,in |
| R2559 |
T4186 |
T4187 |
mark |
that,plays |
| R2560 |
T4187 |
T4179 |
ccomp |
plays,indicate |
| R2561 |
T4188 |
T4187 |
nsubj |
ADAM22,plays |
| R2562 |
T4189 |
T4190 |
det |
an,role |
| R2563 |
T4190 |
T4187 |
dobj |
role,plays |
| R2564 |
T4191 |
T4190 |
amod |
important,role |
| R2565 |
T4192 |
T4187 |
prep |
in,plays |
| R2566 |
T4193 |
T4194 |
compound |
Schwann,cell |
| R2567 |
T4194 |
T4195 |
compound |
cell,differentiation |
| R2568 |
T4195 |
T4192 |
pobj |
differentiation,in |
| R2569 |
T4196 |
T4192 |
punct |
", ",in |
| R2570 |
T4197 |
T4192 |
cc |
but,in |
| R2571 |
T4198 |
T4197 |
neg |
not,but |
| R2572 |
T4199 |
T4192 |
conj |
in,in |
| R2573 |
T4200 |
T4199 |
pobj |
proliferation,in |
| R2574 |
T4201 |
T4179 |
punct |
.,indicate |