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PMC:1142324 / 13637-14389 JSONTXT

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Id Subject Object Predicate Lexical cue
T4079 0-7 DT denotes Another
T4080 20-29 NN denotes phenotype
T4081 8-19 JJ denotes interesting
T4082 64-67 VBD denotes was
T4083 30-38 VBN denotes observed
T4084 39-41 IN denotes in
T4085 42-48 NN denotes ADAM22
T4086 49-58 JJ denotes deficient
T4087 48-49 HYPH denotes -
T4088 59-63 NNS denotes mice
T4089 68-86 NN denotes hypomyelinogenesis
T4090 86-87 . denotes .
T4091 87-184 sentence denotes Histopathological analysis revealed marked hypomyelination in the sciatic and trigeminal nerves.
T4092 88-105 JJ denotes Histopathological
T4093 106-114 NN denotes analysis
T4094 115-123 VBD denotes revealed
T4095 124-130 JJ denotes marked
T4096 131-146 NN denotes hypomyelination
T4097 147-149 IN denotes in
T4098 150-153 DT denotes the
T4099 177-183 NNS denotes nerves
T4100 154-161 JJ denotes sciatic
T4101 162-165 CC denotes and
T4102 166-176 JJ denotes trigeminal
T4103 183-184 . denotes .
T4104 184-255 sentence denotes However, myelin formation in the spinal cord and the brain was normal.
T4105 185-192 RB denotes However
T4106 244-247 VBD denotes was
T4107 192-194 , denotes ,
T4108 194-200 NN denotes myelin
T4109 201-210 NN denotes formation
T4110 211-213 IN denotes in
T4111 214-217 DT denotes the
T4112 225-229 NN denotes cord
T4113 218-224 JJ denotes spinal
T4114 230-233 CC denotes and
T4115 234-237 DT denotes the
T4116 238-243 NN denotes brain
T4117 248-254 JJ denotes normal
T4118 254-255 . denotes .
T4119 255-410 sentence denotes It was therefore evident that hypomyelinogenesis occurred specifically in the peripheral nerves in the knockout mice, suggesting Schwann cell dysfunction.
T4120 256-258 PRP denotes It
T4121 259-262 VBD denotes was
T4122 263-272 RB denotes therefore
T4123 273-280 JJ denotes evident
T4124 281-285 IN denotes that
T4125 305-313 VBD denotes occurred
T4126 286-304 NN denotes hypomyelinogenesis
T4127 314-326 RB denotes specifically
T4128 327-329 IN denotes in
T4129 330-333 DT denotes the
T4130 345-351 NNS denotes nerves
T4131 334-344 JJ denotes peripheral
T4132 352-354 IN denotes in
T4133 355-358 DT denotes the
T4134 368-372 NNS denotes mice
T4135 359-367 NN denotes knockout
T4136 372-374 , denotes ,
T4137 374-384 VBG denotes suggesting
T4138 385-392 NNP denotes Schwann
T4139 393-397 NN denotes cell
T4140 398-409 NN denotes dysfunction
T4141 409-410 . denotes .
T4142 410-567 sentence denotes In the mutant sciatic nerve, the density of pro-myelinating Schwann cells (S100-positive, MBP-negative) was markedly higher than that seen in heterozygotes.
T4143 411-413 IN denotes In
T4144 515-518 VBD denotes was
T4145 414-417 DT denotes the
T4146 433-438 NN denotes nerve
T4147 418-424 NN denotes mutant
T4148 425-432 JJ denotes sciatic
T4149 438-440 , denotes ,
T4150 440-443 DT denotes the
T4151 444-451 NN denotes density
T4152 452-454 IN denotes of
T4153 455-470 VBG denotes pro-myelinating
T4154 479-484 NNS denotes cells
T4155 471-478 NNP denotes Schwann
T4156 485-486 -LRB- denotes (
T4157 505-513 JJ denotes negative
T4158 486-490 NN denotes S100
T4159 491-499 JJ denotes positive
T4160 490-491 HYPH denotes -
T4161 499-501 , denotes ,
T4162 501-504 NN denotes MBP
T4163 504-505 HYPH denotes -
T4164 513-514 -RRB- denotes )
T4165 519-527 RB denotes markedly
T4166 528-534 JJR denotes higher
T4167 535-539 IN denotes than
T4168 540-544 DT denotes that
T4169 545-549 VBN denotes seen
T4170 550-552 IN denotes in
T4171 553-566 NNS denotes heterozygotes
T4172 566-567 . denotes .
T4173 567-752 sentence denotes Higher pro-myelinating Schwann cell density and marked delay in myelin formation indicate that ADAM22 plays an important role in Schwann cell differentiation, but not in proliferation.
T4174 568-574 JJR denotes Higher
T4175 604-611 NN denotes density
T4176 575-590 VBG denotes pro-myelinating
T4177 599-603 NN denotes cell
T4178 591-598 NNP denotes Schwann
T4179 649-657 VBP denotes indicate
T4180 612-615 CC denotes and
T4181 616-622 JJ denotes marked
T4182 623-628 NN denotes delay
T4183 629-631 IN denotes in
T4184 632-638 NN denotes myelin
T4185 639-648 NN denotes formation
T4186 658-662 IN denotes that
T4187 670-675 VBZ denotes plays
T4188 663-669 NN denotes ADAM22
T4189 676-678 DT denotes an
T4190 689-693 NN denotes role
T4191 679-688 JJ denotes important
T4192 694-696 IN denotes in
T4193 697-704 NNP denotes Schwann
T4194 705-709 NN denotes cell
T4195 710-725 NN denotes differentiation
T4196 725-727 , denotes ,
T4197 727-730 CC denotes but
T4198 731-734 RB denotes not
T4199 735-737 IN denotes in
T4200 738-751 NN denotes proliferation
T4201 751-752 . denotes .
R2463 T4079 T4080 det Another,phenotype
R2464 T4080 T4082 nsubj phenotype,was
R2465 T4081 T4080 amod interesting,phenotype
R2466 T4083 T4080 acl observed,phenotype
R2467 T4084 T4083 prep in,observed
R2468 T4085 T4086 npadvmod ADAM22,deficient
R2469 T4086 T4088 amod deficient,mice
R2470 T4087 T4086 punct -,deficient
R2471 T4088 T4084 pobj mice,in
R2472 T4089 T4082 attr hypomyelinogenesis,was
R2473 T4090 T4082 punct .,was
R2474 T4092 T4093 amod Histopathological,analysis
R2475 T4093 T4094 nsubj analysis,revealed
R2476 T4095 T4096 amod marked,hypomyelination
R2477 T4096 T4094 dobj hypomyelination,revealed
R2478 T4097 T4094 prep in,revealed
R2479 T4098 T4099 det the,nerves
R2480 T4099 T4097 pobj nerves,in
R2481 T4100 T4099 amod sciatic,nerves
R2482 T4101 T4100 cc and,sciatic
R2483 T4102 T4100 conj trigeminal,sciatic
R2484 T4103 T4094 punct .,revealed
R2485 T4105 T4106 advmod However,was
R2486 T4107 T4106 punct ", ",was
R2487 T4108 T4109 compound myelin,formation
R2488 T4109 T4106 nsubj formation,was
R2489 T4110 T4109 prep in,formation
R2490 T4111 T4112 det the,cord
R2491 T4112 T4110 pobj cord,in
R2492 T4113 T4112 amod spinal,cord
R2493 T4114 T4112 cc and,cord
R2494 T4115 T4116 det the,brain
R2495 T4116 T4112 conj brain,cord
R2496 T4117 T4106 acomp normal,was
R2497 T4118 T4106 punct .,was
R2498 T4120 T4121 nsubj It,was
R2499 T4122 T4121 advmod therefore,was
R2500 T4123 T4121 acomp evident,was
R2501 T4124 T4125 mark that,occurred
R2502 T4125 T4121 ccomp occurred,was
R2503 T4126 T4125 nsubj hypomyelinogenesis,occurred
R2504 T4127 T4128 advmod specifically,in
R2505 T4128 T4125 prep in,occurred
R2506 T4129 T4130 det the,nerves
R2507 T4130 T4128 pobj nerves,in
R2508 T4131 T4130 amod peripheral,nerves
R2509 T4132 T4125 prep in,occurred
R2510 T4133 T4134 det the,mice
R2511 T4134 T4132 pobj mice,in
R2512 T4135 T4134 compound knockout,mice
R2513 T4136 T4125 punct ", ",occurred
R2514 T4137 T4125 advcl suggesting,occurred
R2515 T4138 T4139 compound Schwann,cell
R2516 T4139 T4140 compound cell,dysfunction
R2517 T4140 T4137 dobj dysfunction,suggesting
R2518 T4141 T4121 punct .,was
R2519 T4143 T4144 prep In,was
R2520 T4145 T4146 det the,nerve
R2521 T4146 T4143 pobj nerve,In
R2522 T4147 T4146 nmod mutant,nerve
R2523 T4148 T4146 amod sciatic,nerve
R2524 T4149 T4144 punct ", ",was
R2525 T4150 T4151 det the,density
R2526 T4151 T4144 nsubj density,was
R2527 T4152 T4151 prep of,density
R2528 T4153 T4154 amod pro-myelinating,cells
R2529 T4154 T4152 pobj cells,of
R2530 T4155 T4154 compound Schwann,cells
R2531 T4156 T4157 punct (,negative
R2532 T4157 T4154 parataxis negative,cells
R2533 T4158 T4159 npadvmod S100,positive
R2534 T4159 T4157 amod positive,negative
R2535 T4160 T4159 punct -,positive
R2536 T4161 T4157 punct ", ",negative
R2537 T4162 T4157 npadvmod MBP,negative
R2538 T4163 T4157 punct -,negative
R2539 T4164 T4157 punct ),negative
R2540 T4165 T4166 advmod markedly,higher
R2541 T4166 T4144 acomp higher,was
R2542 T4167 T4166 prep than,higher
R2543 T4168 T4167 pobj that,than
R2544 T4169 T4168 acl seen,that
R2545 T4170 T4169 prep in,seen
R2546 T4171 T4170 pobj heterozygotes,in
R2547 T4172 T4144 punct .,was
R2548 T4174 T4175 amod Higher,density
R2549 T4175 T4179 nsubj density,indicate
R2550 T4176 T4177 amod pro-myelinating,cell
R2551 T4177 T4175 compound cell,density
R2552 T4178 T4177 compound Schwann,cell
R2553 T4180 T4175 cc and,density
R2554 T4181 T4182 amod marked,delay
R2555 T4182 T4175 conj delay,density
R2556 T4183 T4182 prep in,delay
R2557 T4184 T4185 compound myelin,formation
R2558 T4185 T4183 pobj formation,in
R2559 T4186 T4187 mark that,plays
R2560 T4187 T4179 ccomp plays,indicate
R2561 T4188 T4187 nsubj ADAM22,plays
R2562 T4189 T4190 det an,role
R2563 T4190 T4187 dobj role,plays
R2564 T4191 T4190 amod important,role
R2565 T4192 T4187 prep in,plays
R2566 T4193 T4194 compound Schwann,cell
R2567 T4194 T4195 compound cell,differentiation
R2568 T4195 T4192 pobj differentiation,in
R2569 T4196 T4192 punct ", ",in
R2570 T4197 T4192 cc but,in
R2571 T4198 T4197 neg not,but
R2572 T4199 T4192 conj in,in
R2573 T4200 T4199 pobj proliferation,in
R2574 T4201 T4179 punct .,indicate

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T3624 42-48 PR_EXT:000003718 denotes ADAM22
T3625 59-63 NCBITaxon:10088 denotes mice
T3626 72-86 GO_EXT:myelin_assembly_or_myelination denotes myelinogenesis
T3627 135-146 GO_EXT:myelin_assembly_or_myelination denotes myelination
T3629 154-161,177-183 UBERON:0001322 denotes sciatic nerves
T3630 166-183 UBERON:0001645 denotes trigeminal nerves
T3631 194-200 UBERON:0000345 denotes myelin
T3632 194-210 GO_EXT:myelin_assembly_or_myelination denotes myelin formation
T3633 218-229 UBERON:0002240 denotes spinal cord
T3634 238-243 UBERON:0000955 denotes brain
T3635 290-304 GO_EXT:myelin_assembly_or_myelination denotes myelinogenesis
T3636 334-351 UBERON:0001021 denotes peripheral nerves
T3637 368-372 NCBITaxon:10088 denotes mice
T3638 385-397 CL:0002573 denotes Schwann cell
T3639 393-397 CL_GO_EXT:cell denotes cell
T3640 418-424 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T3641 425-438 UBERON:0001322 denotes sciatic nerve
T3642 455-484 CL:0000218 denotes pro-myelinating Schwann cells
T3643 459-470 GO_EXT:myelin_assembly_or_myelination denotes myelinating
T3644 479-484 CL_GO_EXT:cell denotes cells
T3645 501-504 PR_EXT:000010228 denotes MBP
T3646 575-603 CL:0000218 denotes pro-myelinating Schwann cell
T3647 579-590 GO_EXT:myelin_assembly_or_myelination denotes myelinating
T3648 599-603 CL_GO_EXT:cell denotes cell
T3649 632-638 UBERON:0000345 denotes myelin
T3650 632-648 GO_EXT:myelin_assembly_or_myelination denotes myelin formation
T3651 663-669 PR_EXT:000003718 denotes ADAM22
T3652 697-709 CL:0002573 denotes Schwann cell
T3654 697-709,738-751 GO:0014010 denotes Schwann cell proliferation
T3655 705-709 CL_GO_EXT:cell denotes cell
T3656 705-725 GO:0030154 denotes cell differentiation

craft-ca-core-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T3505 42-48 PR:000003718 denotes ADAM22
T3506 59-63 NCBITaxon:10088 denotes mice
T3508 154-161,177-183 UBERON:0001322 denotes sciatic nerves
T3509 166-183 UBERON:0001645 denotes trigeminal nerves
T3510 194-200 UBERON:0000345 denotes myelin
T3511 218-229 UBERON:0002240 denotes spinal cord
T3512 238-243 UBERON:0000955 denotes brain
T3513 334-351 UBERON:0001021 denotes peripheral nerves
T3514 368-372 NCBITaxon:10088 denotes mice
T3515 385-397 CL:0002573 denotes Schwann cell
T3516 425-438 UBERON:0001322 denotes sciatic nerve
T3517 455-484 CL:0000218 denotes pro-myelinating Schwann cells
T3518 501-504 PR:000010228 denotes MBP
T3519 575-603 CL:0000218 denotes pro-myelinating Schwann cell
T3520 632-638 UBERON:0000345 denotes myelin
T3521 663-669 PR:000003718 denotes ADAM22
T3522 697-709 CL:0002573 denotes Schwann cell
T3524 697-709,738-751 GO:0014010 denotes Schwann cell proliferation
T3525 705-725 GO:0030154 denotes cell differentiation