PMC:1140370 / 30102-30344
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1140370","sourcedb":"PMC","sourceid":"1140370","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1140370","text":" At each fork, one Mcm4/6/7 complex is likely to encircle the single-stranded DNA strand and two hexamers may bind symmetrically to the bubble substrate, forming a double hexameric structure on the bubble (see schematic drawing of Figure 1A).","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T9387","span":{"begin":0,"end":242},"obj":"sentence"},{"id":"T9388","span":{"begin":1,"end":3},"obj":"IN"},{"id":"T9389","span":{"begin":36,"end":38},"obj":"VBZ"},{"id":"T9390","span":{"begin":4,"end":8},"obj":"DT"},{"id":"T9391","span":{"begin":9,"end":13},"obj":"NN"},{"id":"T9392","span":{"begin":13,"end":15},"obj":","},{"id":"T9393","span":{"begin":15,"end":18},"obj":"CD"},{"id":"T9394","span":{"begin":28,"end":35},"obj":"NN"},{"id":"T9395","span":{"begin":19,"end":23},"obj":"NN"},{"id":"T9396","span":{"begin":23,"end":24},"obj":"HYPH"},{"id":"T9397","span":{"begin":24,"end":25},"obj":"CD"},{"id":"T9398","span":{"begin":25,"end":26},"obj":"HYPH"},{"id":"T9399","span":{"begin":26,"end":27},"obj":"CD"},{"id":"T9400","span":{"begin":39,"end":45},"obj":"JJ"},{"id":"T9401","span":{"begin":46,"end":48},"obj":"TO"},{"id":"T9402","span":{"begin":49,"end":57},"obj":"VB"},{"id":"T9403","span":{"begin":58,"end":61},"obj":"DT"},{"id":"T9404","span":{"begin":82,"end":88},"obj":"NN"},{"id":"T9405","span":{"begin":62,"end":68},"obj":"JJ"},{"id":"T9406","span":{"begin":69,"end":77},"obj":"VBN"},{"id":"T9407","span":{"begin":68,"end":69},"obj":"HYPH"},{"id":"T9408","span":{"begin":78,"end":81},"obj":"NN"},{"id":"T9409","span":{"begin":89,"end":92},"obj":"CC"},{"id":"T9410","span":{"begin":93,"end":96},"obj":"CD"},{"id":"T9411","span":{"begin":97,"end":105},"obj":"NNS"},{"id":"T9412","span":{"begin":110,"end":114},"obj":"VB"},{"id":"T9413","span":{"begin":106,"end":109},"obj":"MD"},{"id":"T9414","span":{"begin":115,"end":128},"obj":"RB"},{"id":"T9415","span":{"begin":129,"end":131},"obj":"IN"},{"id":"T9416","span":{"begin":132,"end":135},"obj":"DT"},{"id":"T9417","span":{"begin":143,"end":152},"obj":"NN"},{"id":"T9418","span":{"begin":136,"end":142},"obj":"NN"},{"id":"T9419","span":{"begin":152,"end":154},"obj":","},{"id":"T9420","span":{"begin":154,"end":161},"obj":"VBG"},{"id":"T9421","span":{"begin":162,"end":163},"obj":"DT"},{"id":"T9422","span":{"begin":181,"end":190},"obj":"NN"},{"id":"T9423","span":{"begin":164,"end":170},"obj":"JJ"},{"id":"T9424","span":{"begin":171,"end":180},"obj":"JJ"},{"id":"T9425","span":{"begin":191,"end":193},"obj":"IN"},{"id":"T9426","span":{"begin":194,"end":197},"obj":"DT"},{"id":"T9427","span":{"begin":198,"end":204},"obj":"NN"},{"id":"T9428","span":{"begin":205,"end":206},"obj":"-LRB-"},{"id":"T9429","span":{"begin":206,"end":209},"obj":"VB"},{"id":"T9430","span":{"begin":210,"end":219},"obj":"JJ"},{"id":"T9431","span":{"begin":220,"end":227},"obj":"NN"},{"id":"T9432","span":{"begin":228,"end":230},"obj":"IN"},{"id":"T9433","span":{"begin":231,"end":237},"obj":"NN"},{"id":"T9434","span":{"begin":238,"end":240},"obj":"NN"},{"id":"T9435","span":{"begin":240,"end":241},"obj":"-RRB-"},{"id":"T9436","span":{"begin":241,"end":242},"obj":"."}],"relations":[{"id":"R6279","pred":"prep","subj":"T9388","obj":"T9389"},{"id":"R6280","pred":"det","subj":"T9390","obj":"T9391"},{"id":"R6281","pred":"pobj","subj":"T9391","obj":"T9388"},{"id":"R6282","pred":"punct","subj":"T9392","obj":"T9389"},{"id":"R6283","pred":"nummod","subj":"T9393","obj":"T9394"},{"id":"R6284","pred":"nsubj","subj":"T9394","obj":"T9389"},{"id":"R6285","pred":"nmod","subj":"T9395","obj":"T9394"},{"id":"R6286","pred":"punct","subj":"T9396","obj":"T9395"},{"id":"R6287","pred":"nummod","subj":"T9397","obj":"T9395"},{"id":"R6288","pred":"punct","subj":"T9398","obj":"T9395"},{"id":"R6289","pred":"nummod","subj":"T9399","obj":"T9395"},{"id":"R6290","pred":"acomp","subj":"T9400","obj":"T9389"},{"id":"R6291","pred":"aux","subj":"T9401","obj":"T9402"},{"id":"R6292","pred":"xcomp","subj":"T9402","obj":"T9400"},{"id":"R6293","pred":"det","subj":"T9403","obj":"T9404"},{"id":"R6294","pred":"dobj","subj":"T9404","obj":"T9402"},{"id":"R6295","pred":"amod","subj":"T9405","obj":"T9406"},{"id":"R6296","pred":"amod","subj":"T9406","obj":"T9404"},{"id":"R6297","pred":"punct","subj":"T9407","obj":"T9406"},{"id":"R6298","pred":"compound","subj":"T9408","obj":"T9404"},{"id":"R6299","pred":"cc","subj":"T9409","obj":"T9389"},{"id":"R6300","pred":"nummod","subj":"T9410","obj":"T9411"},{"id":"R6301","pred":"nsubj","subj":"T9411","obj":"T9412"},{"id":"R6302","pred":"conj","subj":"T9412","obj":"T9389"},{"id":"R6303","pred":"aux","subj":"T9413","obj":"T9412"},{"id":"R6304","pred":"advmod","subj":"T9414","obj":"T9412"},{"id":"R6305","pred":"prep","subj":"T9415","obj":"T9412"},{"id":"R6306","pred":"det","subj":"T9416","obj":"T9417"},{"id":"R6307","pred":"pobj","subj":"T9417","obj":"T9415"},{"id":"R6308","pred":"compound","subj":"T9418","obj":"T9417"},{"id":"R6309","pred":"punct","subj":"T9419","obj":"T9412"},{"id":"R6310","pred":"advcl","subj":"T9420","obj":"T9412"},{"id":"R6311","pred":"det","subj":"T9421","obj":"T9422"},{"id":"R6312","pred":"dobj","subj":"T9422","obj":"T9420"},{"id":"R6313","pred":"amod","subj":"T9423","obj":"T9424"},{"id":"R6314","pred":"amod","subj":"T9424","obj":"T9422"},{"id":"R6315","pred":"prep","subj":"T9425","obj":"T9420"},{"id":"R6316","pred":"det","subj":"T9426","obj":"T9427"},{"id":"R6317","pred":"pobj","subj":"T9427","obj":"T9425"},{"id":"R6318","pred":"punct","subj":"T9428","obj":"T9429"},{"id":"R6319","pred":"parataxis","subj":"T9429","obj":"T9420"},{"id":"R6320","pred":"amod","subj":"T9430","obj":"T9431"},{"id":"R6321","pred":"dobj","subj":"T9431","obj":"T9429"},{"id":"R6322","pred":"prep","subj":"T9432","obj":"T9431"},{"id":"R6323","pred":"compound","subj":"T9433","obj":"T9434"},{"id":"R6324","pred":"pobj","subj":"T9434","obj":"T9432"},{"id":"R6325","pred":"punct","subj":"T9435","obj":"T9429"},{"id":"R6326","pred":"punct","subj":"T9436","obj":"T9412"}],"attributes":[{"subj":"T9387","pred":"source","obj":"craft-sa-dev"},{"subj":"T9388","pred":"source","obj":"craft-sa-dev"},{"subj":"T9389","pred":"source","obj":"craft-sa-dev"},{"subj":"T9390","pred":"source","obj":"craft-sa-dev"},{"subj":"T9391","pred":"source","obj":"craft-sa-dev"},{"subj":"T9392","pred":"source","obj":"craft-sa-dev"},{"subj":"T9393","pred":"source","obj":"craft-sa-dev"},{"subj":"T9394","pred":"source","obj":"craft-sa-dev"},{"subj":"T9395","pred":"source","obj":"craft-sa-dev"},{"subj":"T9396","pred":"source","obj":"craft-sa-dev"},{"subj":"T9397","pred":"source","obj":"craft-sa-dev"},{"subj":"T9398","pred":"source","obj":"craft-sa-dev"},{"subj":"T9399","pred":"source","obj":"craft-sa-dev"},{"subj":"T9400","pred":"source","obj":"craft-sa-dev"},{"subj":"T9401","pred":"source","obj":"craft-sa-dev"},{"subj":"T9402","pred":"source","obj":"craft-sa-dev"},{"subj":"T9403","pred":"source","obj":"craft-sa-dev"},{"subj":"T9404","pred":"source","obj":"craft-sa-dev"},{"subj":"T9405","pred":"source","obj":"craft-sa-dev"},{"subj":"T9406","pred":"source","obj":"craft-sa-dev"},{"subj":"T9407","pred":"source","obj":"craft-sa-dev"},{"subj":"T9408","pred":"source","obj":"craft-sa-dev"},{"subj":"T9409","pred":"source","obj":"craft-sa-dev"},{"subj":"T9410","pred":"source","obj":"craft-sa-dev"},{"subj":"T9411","pred":"source","obj":"craft-sa-dev"},{"subj":"T9412","pred":"source","obj":"craft-sa-dev"},{"subj":"T9413","pred":"source","obj":"craft-sa-dev"},{"subj":"T9414","pred":"source","obj":"craft-sa-dev"},{"subj":"T9415","pred":"source","obj":"craft-sa-dev"},{"subj":"T9416","pred":"source","obj":"craft-sa-dev"},{"subj":"T9417","pred":"source","obj":"craft-sa-dev"},{"subj":"T9418","pred":"source","obj":"craft-sa-dev"},{"subj":"T9419","pred":"source","obj":"craft-sa-dev"},{"subj":"T9420","pred":"source","obj":"craft-sa-dev"},{"subj":"T9421","pred":"source","obj":"craft-sa-dev"},{"subj":"T9422","pred":"source","obj":"craft-sa-dev"},{"subj":"T9423","pred":"source","obj":"craft-sa-dev"},{"subj":"T9424","pred":"source","obj":"craft-sa-dev"},{"subj":"T9425","pred":"source","obj":"craft-sa-dev"},{"subj":"T9426","pred":"source","obj":"craft-sa-dev"},{"subj":"T9427","pred":"source","obj":"craft-sa-dev"},{"subj":"T9428","pred":"source","obj":"craft-sa-dev"},{"subj":"T9429","pred":"source","obj":"craft-sa-dev"},{"subj":"T9430","pred":"source","obj":"craft-sa-dev"},{"subj":"T9431","pred":"source","obj":"craft-sa-dev"},{"subj":"T9432","pred":"source","obj":"craft-sa-dev"},{"subj":"T9433","pred":"source","obj":"craft-sa-dev"},{"subj":"T9434","pred":"source","obj":"craft-sa-dev"},{"subj":"T9435","pred":"source","obj":"craft-sa-dev"},{"subj":"T9436","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T9062","span":{"begin":9,"end":13},"obj":"GO:0005657"},{"id":"T9063","span":{"begin":19,"end":23},"obj":"PR_EXT:000010246"},{"id":"T9064","span":{"begin":19,"end":35},"obj":"GO:0097373"},{"id":"T9065","span":{"begin":62,"end":81},"obj":"CHEBI_SO_EXT:single_stranded_DNA"},{"id":"T9066","span":{"begin":97,"end":105},"obj":"GO_EXT:hexameric_macromolecular_complex"},{"id":"T9067","span":{"begin":110,"end":114},"obj":"CHEMINF_GO_EXT:chemical_binding_or_bond_formation"},{"id":"T9068","span":{"begin":164,"end":180},"obj":"GO_EXT:double_hexameric_macromolecular_complex"}],"attributes":[{"subj":"T9062","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T9063","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T9064","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T9065","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T9066","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T9067","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T9068","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T8991","span":{"begin":9,"end":13},"obj":"GO:0005657"},{"id":"T8992","span":{"begin":19,"end":23},"obj":"PR:000010246"},{"id":"T8993","span":{"begin":19,"end":35},"obj":"GO:0097373"},{"id":"T8994","span":{"begin":62,"end":77},"obj":"SO:0000984"}],"attributes":[{"subj":"T8991","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T8992","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T8993","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T8994","pred":"source","obj":"craft-ca-core-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#93ecc5","default":true},{"id":"craft-ca-core-ex-dev","color":"#ecab93"},{"id":"craft-ca-core-dev","color":"#9395ec"}]}]}}