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PMC:1140370
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PMC:1140370
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The
ability
of
Mcm4
/
6
/
7
to
unwind
the
bubble
substrate
but
not
the
conventional
duplex
DNA
(
Figures
2
and
13
)
indicates
that
Mcm
can
be
loaded
through
the
single
-
stranded
segment
of
the
bubble
.