PMC:1140370 / 24661-26014 JSONTXT

{"project":"craft-sa-dev","denotations":[{"id":"T7743","span":{"begin":0,"end":3},"obj":"PRP$"},{"id":"T7744","span":{"begin":4,"end":11},"obj":"NNS"},{"id":"T7745","span":{"begin":12,"end":20},"obj":"VBP"},{"id":"T7746","span":{"begin":21,"end":25},"obj":"IN"},{"id":"T7747","span":{"begin":62,"end":70},"obj":"VBN"},{"id":"T7748","span":{"begin":26,"end":33},"obj":"NN"},{"id":"T7749","span":{"begin":34,"end":38},"obj":"JJ"},{"id":"T7750","span":{"begin":33,"end":34},"obj":"HYPH"},{"id":"T7751","span":{"begin":55,"end":58},"obj":"NN"},{"id":"T7752","span":{"begin":39,"end":45},"obj":"JJ"},{"id":"T7753","span":{"begin":46,"end":54},"obj":"VBN"},{"id":"T7754","span":{"begin":45,"end":46},"obj":"HYPH"},{"id":"T7755","span":{"begin":59,"end":61},"obj":"VBZ"},{"id":"T7756","span":{"begin":71,"end":74},"obj":"IN"},{"id":"T7757","span":{"begin":75,"end":82},"obj":"JJ"},{"id":"T7758","span":{"begin":83,"end":90},"obj":"NN"},{"id":"T7759","span":{"begin":91,"end":94},"obj":"CC"},{"id":"T7760","span":{"begin":95,"end":105},"obj":"NN"},{"id":"T7761","span":{"begin":106,"end":108},"obj":"IN"},{"id":"T7762","span":{"begin":109,"end":112},"obj":"DT"},{"id":"T7763","span":{"begin":117,"end":125},"obj":"NN"},{"id":"T7764","span":{"begin":113,"end":116},"obj":"NN"},{"id":"T7765","span":{"begin":125,"end":126},"obj":"."},{"id":"T7766","span":{"begin":126,"end":230},"obj":"sentence"},{"id":"T7767","span":{"begin":127,"end":134},"obj":"RB"},{"id":"T7768","span":{"begin":146,"end":151},"obj":"VBN"},{"id":"T7769","span":{"begin":134,"end":136},"obj":","},{"id":"T7770","span":{"begin":136,"end":138},"obj":"PRP"},{"id":"T7771","span":{"begin":139,"end":141},"obj":"VBZ"},{"id":"T7772","span":{"begin":142,"end":145},"obj":"RB"},{"id":"T7773","span":{"begin":152,"end":159},"obj":"IN"},{"id":"T7774","span":{"begin":182,"end":190},"obj":"VBN"},{"id":"T7775","span":{"begin":160,"end":167},"obj":"NN"},{"id":"T7776","span":{"begin":168,"end":177},"obj":"NNS"},{"id":"T7777","span":{"begin":178,"end":181},"obj":"VBP"},{"id":"T7778","span":{"begin":191,"end":194},"obj":"IN"},{"id":"T7779","span":{"begin":195,"end":205},"obj":"JJ"},{"id":"T7780","span":{"begin":206,"end":215},"obj":"NN"},{"id":"T7781","span":{"begin":216,"end":218},"obj":"IN"},{"id":"T7782","span":{"begin":219,"end":225},"obj":"NN"},{"id":"T7783","span":{"begin":226,"end":229},"obj":"NN"},{"id":"T7784","span":{"begin":229,"end":230},"obj":"."},{"id":"T7785","span":{"begin":230,"end":346},"obj":"sentence"},{"id":"T7786","span":{"begin":231,"end":240},"obj":"RB"},{"id":"T7787","span":{"begin":250,"end":258},"obj":"VBN"},{"id":"T7788","span":{"begin":240,"end":242},"obj":","},{"id":"T7789","span":{"begin":242,"end":244},"obj":"PRP"},{"id":"T7790","span":{"begin":245,"end":249},"obj":"VBP"},{"id":"T7791","span":{"begin":259,"end":266},"obj":"IN"},{"id":"T7792","span":{"begin":315,"end":322},"obj":"VBZ"},{"id":"T7793","span":{"begin":267,"end":270},"obj":"DT"},{"id":"T7794","span":{"begin":282,"end":293},"obj":"NN"},{"id":"T7795","span":{"begin":271,"end":281},"obj":"NN"},{"id":"T7796","span":{"begin":294,"end":296},"obj":"IN"},{"id":"T7797","span":{"begin":297,"end":300},"obj":"DT"},{"id":"T7798","span":{"begin":308,"end":314},"obj":"NN"},{"id":"T7799","span":{"begin":301,"end":307},"obj":"NN"},{"id":"T7800","span":{"begin":323,"end":326},"obj":"PRP$"},{"id":"T7801","span":{"begin":337,"end":345},"obj":"NN"},{"id":"T7802","span":{"begin":327,"end":336},"obj":"NN"},{"id":"T7803","span":{"begin":345,"end":346},"obj":"."},{"id":"T7804","span":{"begin":346,"end":484},"obj":"sentence"},{"id":"T7805","span":{"begin":347,"end":349},"obj":"TO"},{"id":"T7806","span":{"begin":350,"end":357},"obj":"VB"},{"id":"T7807","span":{"begin":373,"end":384},"obj":"VBD"},{"id":"T7808","span":{"begin":358,"end":362},"obj":"DT"},{"id":"T7809","span":{"begin":363,"end":368},"obj":"NN"},{"id":"T7810","span":{"begin":368,"end":370},"obj":","},{"id":"T7811","span":{"begin":370,"end":372},"obj":"PRP"},{"id":"T7812","span":{"begin":385,"end":386},"obj":"DT"},{"id":"T7813","span":{"begin":387,"end":393},"obj":"NN"},{"id":"T7814","span":{"begin":394,"end":396},"obj":"IN"},{"id":"T7815","span":{"begin":397,"end":398},"obj":"NN"},{"id":"T7816","span":{"begin":399,"end":405},"obj":"VBN"},{"id":"T7817","span":{"begin":398,"end":399},"obj":"HYPH"},{"id":"T7818","span":{"begin":413,"end":423},"obj":"NNS"},{"id":"T7819","span":{"begin":406,"end":407},"obj":"NN"},{"id":"T7820","span":{"begin":408,"end":412},"obj":"NN"},{"id":"T7821","span":{"begin":407,"end":408},"obj":"HYPH"},{"id":"T7822","span":{"begin":424,"end":425},"obj":"-LRB-"},{"id":"T7823","span":{"begin":425,"end":426},"obj":"NN"},{"id":"T7824","span":{"begin":427,"end":431},"obj":"NN"},{"id":"T7825","span":{"begin":426,"end":427},"obj":"HYPH"},{"id":"T7826","span":{"begin":431,"end":432},"obj":"-RRB-"},{"id":"T7827","span":{"begin":433,"end":443},"obj":"VBG"},{"id":"T7828","span":{"begin":444,"end":451},"obj":"JJ"},{"id":"T7829","span":{"begin":452,"end":461},"obj":"NNS"},{"id":"T7830","span":{"begin":462,"end":464},"obj":"IN"},{"id":"T7831","span":{"begin":465,"end":468},"obj":"DT"},{"id":"T7832","span":{"begin":476,"end":483},"obj":"NN"},{"id":"T7833","span":{"begin":469,"end":475},"obj":"NN"},{"id":"T7834","span":{"begin":483,"end":484},"obj":"."},{"id":"T7835","span":{"begin":484,"end":557},"obj":"sentence"},{"id":"T7836","span":{"begin":485,"end":489},"obj":"PRP"},{"id":"T7837","span":{"begin":490,"end":497},"obj":"VBD"},{"id":"T7838","span":{"begin":498,"end":504},"obj":"VBN"},{"id":"T7839","span":{"begin":505,"end":513},"obj":"NNS"},{"id":"T7840","span":{"begin":514,"end":516},"obj":"IN"},{"id":"T7841","span":{"begin":517,"end":525},"obj":"NN"},{"id":"T7842","span":{"begin":526,"end":534},"obj":"NNS"},{"id":"T7843","span":{"begin":535,"end":537},"obj":"IN"},{"id":"T7844","span":{"begin":538,"end":541},"obj":"DT"},{"id":"T7845","span":{"begin":550,"end":556},"obj":"NN"},{"id":"T7846","span":{"begin":542,"end":543},"obj":"CD"},{"id":"T7847","span":{"begin":545,"end":549},"obj":"NN"},{"id":"T7848","span":{"begin":543,"end":544},"obj":"SYM"},{"id":"T7849","span":{"begin":544,"end":545},"obj":"HYPH"},{"id":"T7850","span":{"begin":556,"end":557},"obj":"."},{"id":"T7851","span":{"begin":557,"end":734},"obj":"sentence"},{"id":"T7852","span":{"begin":558,"end":560},"obj":"IN"},{"id":"T7853","span":{"begin":588,"end":593},"obj":"VBD"},{"id":"T7854","span":{"begin":561,"end":564},"obj":"NN"},{"id":"T7855","span":{"begin":565,"end":570},"obj":"NN"},{"id":"T7856","span":{"begin":571,"end":577},"obj":"NNS"},{"id":"T7857","span":{"begin":577,"end":579},"obj":","},{"id":"T7858","span":{"begin":579,"end":583},"obj":"NN"},{"id":"T7859","span":{"begin":583,"end":584},"obj":"HYPH"},{"id":"T7860","span":{"begin":584,"end":585},"obj":"CD"},{"id":"T7861","span":{"begin":585,"end":586},"obj":"HYPH"},{"id":"T7862","span":{"begin":586,"end":587},"obj":"CD"},{"id":"T7863","span":{"begin":594,"end":596},"obj":"IN"},{"id":"T7864","span":{"begin":597,"end":602},"obj":"DT"},{"id":"T7865","span":{"begin":610,"end":620},"obj":"NNS"},{"id":"T7866","span":{"begin":603,"end":604},"obj":"NN"},{"id":"T7867","span":{"begin":605,"end":609},"obj":"NN"},{"id":"T7868","span":{"begin":604,"end":605},"obj":"HYPH"},{"id":"T7869","span":{"begin":621,"end":625},"obj":"IN"},{"id":"T7870","span":{"begin":626,"end":635},"obj":"JJ"},{"id":"T7871","span":{"begin":636,"end":644},"obj":"NN"},{"id":"T7872","span":{"begin":645,"end":646},"obj":"-LRB-"},{"id":"T7873","span":{"begin":653,"end":655},"obj":"NN"},{"id":"T7874","span":{"begin":646,"end":652},"obj":"NN"},{"id":"T7875","span":{"begin":655,"end":656},"obj":"-RRB-"},{"id":"T7876","span":{"begin":656,"end":658},"obj":","},{"id":"T7877","span":{"begin":658,"end":668},"obj":"JJ"},{"id":"T7878","span":{"begin":669,"end":673},"obj":"IN"},{"id":"T7879","span":{"begin":674,"end":677},"obj":"DT"},{"id":"T7880","span":{"begin":678,"end":684},"obj":"NN"},{"id":"T7881","span":{"begin":685,"end":689},"obj":"IN"},{"id":"T7882","span":{"begin":703,"end":708},"obj":"VBZ"},{"id":"T7883","span":{"begin":690,"end":693},"obj":"DT"},{"id":"T7884","span":{"begin":694,"end":698},"obj":"NN"},{"id":"T7885","span":{"begin":698,"end":699},"obj":"HYPH"},{"id":"T7886","span":{"begin":699,"end":700},"obj":"CD"},{"id":"T7887","span":{"begin":700,"end":701},"obj":"HYPH"},{"id":"T7888","span":{"begin":701,"end":702},"obj":"CD"},{"id":"T7889","span":{"begin":709,"end":711},"obj":"IN"},{"id":"T7890","span":{"begin":712,"end":718},"obj":"JJ"},{"id":"T7891","span":{"begin":719,"end":727},"obj":"VBN"},{"id":"T7892","span":{"begin":718,"end":719},"obj":"HYPH"},{"id":"T7893","span":{"begin":728,"end":733},"obj":"NNS"},{"id":"T7894","span":{"begin":733,"end":734},"obj":"."},{"id":"T7895","span":{"begin":734,"end":886},"obj":"sentence"},{"id":"T7896","span":{"begin":735,"end":742},"obj":"RB"},{"id":"T7897","span":{"begin":794,"end":803},"obj":"VBN"},{"id":"T7898","span":{"begin":742,"end":744},"obj":","},{"id":"T7899","span":{"begin":744,"end":746},"obj":"IN"},{"id":"T7900","span":{"begin":747,"end":750},"obj":"NN"},{"id":"T7901","span":{"begin":751,"end":759},"obj":"NN"},{"id":"T7902","span":{"begin":760,"end":766},"obj":"NNS"},{"id":"T7903","span":{"begin":766,"end":768},"obj":","},{"id":"T7904","span":{"begin":768,"end":769},"obj":"NN"},{"id":"T7905","span":{"begin":770,"end":774},"obj":"NN"},{"id":"T7906","span":{"begin":769,"end":770},"obj":"HYPH"},{"id":"T7907","span":{"begin":774,"end":775},"obj":"HYPH"},{"id":"T7908","span":{"begin":775,"end":776},"obj":"-LRB-"},{"id":"T7909","span":{"begin":778,"end":779},"obj":"NN"},{"id":"T7910","span":{"begin":776,"end":777},"obj":"NN"},{"id":"T7911","span":{"begin":777,"end":778},"obj":":"},{"id":"T7912","span":{"begin":779,"end":780},"obj":"-RRB-"},{"id":"T7913","span":{"begin":780,"end":782},"obj":"CD"},{"id":"T7914","span":{"begin":783,"end":786},"obj":"VBD"},{"id":"T7915","span":{"begin":787,"end":793},"obj":"RB"},{"id":"T7916","span":{"begin":804,"end":806},"obj":"IN"},{"id":"T7917","span":{"begin":807,"end":811},"obj":"NN"},{"id":"T7918","span":{"begin":811,"end":812},"obj":"HYPH"},{"id":"T7919","span":{"begin":812,"end":813},"obj":"CD"},{"id":"T7920","span":{"begin":813,"end":814},"obj":"HYPH"},{"id":"T7921","span":{"begin":814,"end":815},"obj":"CD"},{"id":"T7922","span":{"begin":815,"end":817},"obj":","},{"id":"T7923","span":{"begin":817,"end":820},"obj":"CC"},{"id":"T7924","span":{"begin":821,"end":824},"obj":"VBD"},{"id":"T7925","span":{"begin":833,"end":842},"obj":"VBN"},{"id":"T7926","span":{"begin":825,"end":832},"obj":"RB"},{"id":"T7927","span":{"begin":843,"end":845},"obj":"IN"},{"id":"T7928","span":{"begin":846,"end":850},"obj":"NN"},{"id":"T7929","span":{"begin":865,"end":873},"obj":"NN"},{"id":"T7930","span":{"begin":851,"end":852},"obj":"NN"},{"id":"T7931","span":{"begin":853,"end":860},"obj":"NN"},{"id":"T7932","span":{"begin":852,"end":853},"obj":"HYPH"},{"id":"T7933","span":{"begin":861,"end":864},"obj":"NN"},{"id":"T7934","span":{"begin":874,"end":875},"obj":"-LRB-"},{"id":"T7935","span":{"begin":882,"end":884},"obj":"NN"},{"id":"T7936","span":{"begin":875,"end":881},"obj":"NN"},{"id":"T7937","span":{"begin":884,"end":885},"obj":"-RRB-"},{"id":"T7938","span":{"begin":885,"end":886},"obj":"."},{"id":"T7939","span":{"begin":886,"end":1052},"obj":"sentence"},{"id":"T7940","span":{"begin":887,"end":891},"obj":"WRB"},{"id":"T7941","span":{"begin":914,"end":922},"obj":"VBN"},{"id":"T7942","span":{"begin":892,"end":899},"obj":"NN"},{"id":"T7943","span":{"begin":900,"end":902},"obj":"CC"},{"id":"T7944","span":{"begin":903,"end":910},"obj":"NN"},{"id":"T7945","span":{"begin":911,"end":913},"obj":"VBZ"},{"id":"T7946","span":{"begin":998,"end":1007},"obj":"VBD"},{"id":"T7947","span":{"begin":923,"end":925},"obj":"IN"},{"id":"T7948","span":{"begin":926,"end":931},"obj":"DT"},{"id":"T7949","span":{"begin":938,"end":948},"obj":"NN"},{"id":"T7950","span":{"begin":932,"end":937},"obj":"JJ"},{"id":"T7951","span":{"begin":949,"end":950},"obj":"-LRB-"},{"id":"T7952","span":{"begin":950,"end":957},"obj":"NNS"},{"id":"T7953","span":{"begin":958,"end":960},"obj":"IN"},{"id":"T7954","span":{"begin":961,"end":964},"obj":"NN"},{"id":"T7955","span":{"begin":965,"end":967},"obj":"CC"},{"id":"T7956","span":{"begin":968,"end":971},"obj":"NN"},{"id":"T7957","span":{"begin":971,"end":972},"obj":"-RRB-"},{"id":"T7958","span":{"begin":972,"end":974},"obj":","},{"id":"T7959","span":{"begin":974,"end":977},"obj":"DT"},{"id":"T7960","span":{"begin":978,"end":984},"obj":"NN"},{"id":"T7961","span":{"begin":985,"end":987},"obj":"IN"},{"id":"T7962","span":{"begin":988,"end":997},"obj":"NN"},{"id":"T7963","span":{"begin":1008,"end":1009},"obj":"-LRB-"},{"id":"T7964","span":{"begin":1021,"end":1024},"obj":"NN"},{"id":"T7965","span":{"begin":1009,"end":1010},"obj":"NN"},{"id":"T7966","span":{"begin":1011,"end":1015},"obj":"NN"},{"id":"T7967","span":{"begin":1010,"end":1011},"obj":"HYPH"},{"id":"T7968","span":{"begin":1015,"end":1016},"obj":"HYPH"},{"id":"T7969","span":{"begin":1016,"end":1017},"obj":"-LRB-"},{"id":"T7970","span":{"begin":1017,"end":1020},"obj":"NN"},{"id":"T7971","span":{"begin":1020,"end":1021},"obj":":"},{"id":"T7972","span":{"begin":1024,"end":1025},"obj":"-RRB-"},{"id":"T7973","span":{"begin":1025,"end":1027},"obj":"CD"},{"id":"T7974","span":{"begin":1028,"end":1031},"obj":"CC"},{"id":"T7975","span":{"begin":1032,"end":1033},"obj":"NN"},{"id":"T7976","span":{"begin":1034,"end":1038},"obj":"NN"},{"id":"T7977","span":{"begin":1033,"end":1034},"obj":"HYPH"},{"id":"T7978","span":{"begin":1044,"end":1047},"obj":"NN"},{"id":"T7979","span":{"begin":1038,"end":1039},"obj":"HYPH"},{"id":"T7980","span":{"begin":1039,"end":1040},"obj":"-LRB-"},{"id":"T7981","span":{"begin":1040,"end":1043},"obj":"NN"},{"id":"T7982","span":{"begin":1043,"end":1044},"obj":":"},{"id":"T7983","span":{"begin":1047,"end":1048},"obj":"-RRB-"},{"id":"T7984","span":{"begin":1048,"end":1050},"obj":"CD"},{"id":"T7985","span":{"begin":1050,"end":1051},"obj":"-RRB-"},{"id":"T7986","span":{"begin":1051,"end":1052},"obj":"."},{"id":"T7987","span":{"begin":1052,"end":1257},"obj":"sentence"},{"id":"T7988","span":{"begin":1053,"end":1056},"obj":"DT"},{"id":"T7989","span":{"begin":1057,"end":1067},"obj":"NN"},{"id":"T7990","span":{"begin":1092,"end":1102},"obj":"VBN"},{"id":"T7991","span":{"begin":1068,"end":1070},"obj":"IN"},{"id":"T7992","span":{"begin":1071,"end":1080},"obj":"NN"},{"id":"T7993","span":{"begin":1081,"end":1083},"obj":"VBZ"},{"id":"T7994","span":{"begin":1084,"end":1091},"obj":"RB"},{"id":"T7995","span":{"begin":1103,"end":1107},"obj":"IN"},{"id":"T7996","span":{"begin":1108,"end":1111},"obj":"DT"},{"id":"T7997","span":{"begin":1112,"end":1119},"obj":"NN"},{"id":"T7998","span":{"begin":1120,"end":1122},"obj":"IN"},{"id":"T7999","span":{"begin":1123,"end":1125},"obj":"NN"},{"id":"T8000","span":{"begin":1126,"end":1131},"obj":"NNS"},{"id":"T8001","span":{"begin":1132,"end":1134},"obj":"IN"},{"id":"T8002","span":{"begin":1135,"end":1138},"obj":"DT"},{"id":"T8003","span":{"begin":1146,"end":1153},"obj":"NN"},{"id":"T8004","span":{"begin":1139,"end":1145},"obj":"NN"},{"id":"T8005","span":{"begin":1154,"end":1155},"obj":"-LRB-"},{"id":"T8006","span":{"begin":1168,"end":1172},"obj":"NN"},{"id":"T8007","span":{"begin":1155,"end":1156},"obj":"NN"},{"id":"T8008","span":{"begin":1157,"end":1161},"obj":"NN"},{"id":"T8009","span":{"begin":1156,"end":1157},"obj":"HYPH"},{"id":"T8010","span":{"begin":1161,"end":1162},"obj":"HYPH"},{"id":"T8011","span":{"begin":1162,"end":1163},"obj":"-LRB-"},{"id":"T8012","span":{"begin":1163,"end":1167},"obj":"NN"},{"id":"T8013","span":{"begin":1167,"end":1168},"obj":":"},{"id":"T8014","span":{"begin":1172,"end":1173},"obj":"-RRB-"},{"id":"T8015","span":{"begin":1173,"end":1175},"obj":"CD"},{"id":"T8016","span":{"begin":1175,"end":1177},"obj":","},{"id":"T8017","span":{"begin":1177,"end":1178},"obj":"NN"},{"id":"T8018","span":{"begin":1179,"end":1183},"obj":"NN"},{"id":"T8019","span":{"begin":1178,"end":1179},"obj":"HYPH"},{"id":"T8020","span":{"begin":1190,"end":1194},"obj":"NN"},{"id":"T8021","span":{"begin":1183,"end":1184},"obj":"HYPH"},{"id":"T8022","span":{"begin":1184,"end":1185},"obj":"-LRB-"},{"id":"T8023","span":{"begin":1185,"end":1189},"obj":"NN"},{"id":"T8024","span":{"begin":1189,"end":1190},"obj":":"},{"id":"T8025","span":{"begin":1194,"end":1195},"obj":"-RRB-"},{"id":"T8026","span":{"begin":1195,"end":1197},"obj":"CD"},{"id":"T8027","span":{"begin":1197,"end":1199},"obj":","},{"id":"T8028","span":{"begin":1199,"end":1200},"obj":"NN"},{"id":"T8029","span":{"begin":1201,"end":1205},"obj":"NN"},{"id":"T8030","span":{"begin":1200,"end":1201},"obj":"HYPH"},{"id":"T8031","span":{"begin":1212,"end":1216},"obj":"NN"},{"id":"T8032","span":{"begin":1205,"end":1206},"obj":"HYPH"},{"id":"T8033","span":{"begin":1206,"end":1207},"obj":"-LRB-"},{"id":"T8034","span":{"begin":1207,"end":1211},"obj":"NN"},{"id":"T8035","span":{"begin":1211,"end":1212},"obj":":"},{"id":"T8036","span":{"begin":1216,"end":1217},"obj":"-RRB-"},{"id":"T8037","span":{"begin":1217,"end":1219},"obj":"CD"},{"id":"T8038","span":{"begin":1220,"end":1223},"obj":"CC"},{"id":"T8039","span":{"begin":1224,"end":1225},"obj":"NN"},{"id":"T8040","span":{"begin":1226,"end":1230},"obj":"NN"},{"id":"T8041","span":{"begin":1225,"end":1226},"obj":"HYPH"},{"id":"T8042","span":{"begin":1237,"end":1241},"obj":"NN"},{"id":"T8043","span":{"begin":1230,"end":1231},"obj":"HYPH"},{"id":"T8044","span":{"begin":1231,"end":1232},"obj":"-LRB-"},{"id":"T8045","span":{"begin":1232,"end":1236},"obj":"NN"},{"id":"T8046","span":{"begin":1236,"end":1237},"obj":":"},{"id":"T8047","span":{"begin":1241,"end":1242},"obj":"-RRB-"},{"id":"T8048","span":{"begin":1242,"end":1244},"obj":"CD"},{"id":"T8049","span":{"begin":1244,"end":1245},"obj":":"},{"id":"T8050","span":{"begin":1253,"end":1255},"obj":"NN"},{"id":"T8051","span":{"begin":1246,"end":1252},"obj":"NN"},{"id":"T8052","span":{"begin":1255,"end":1256},"obj":"-RRB-"},{"id":"T8053","span":{"begin":1256,"end":1257},"obj":"."},{"id":"T8054","span":{"begin":1257,"end":1353},"obj":"sentence"},{"id":"T8055","span":{"begin":1258,"end":1260},"obj":"PRP"},{"id":"T8056","span":{"begin":1261,"end":1268},"obj":"VBZ"},{"id":"T8057","span":{"begin":1269,"end":1273},"obj":"IN"},{"id":"T8058","span":{"begin":1333,"end":1340},"obj":"VBN"},{"id":"T8059","span":{"begin":1274,"end":1277},"obj":"DT"},{"id":"T8060","span":{"begin":1285,"end":1292},"obj":"NN"},{"id":"T8061","span":{"begin":1278,"end":1284},"obj":"NN"},{"id":"T8062","span":{"begin":1293,"end":1303},"obj":"VBG"},{"id":"T8063","span":{"begin":1304,"end":1305},"obj":"SYM"},{"id":"T8064","span":{"begin":1305,"end":1307},"obj":"CD"},{"id":"T8065","span":{"begin":1307,"end":1308},"obj":"NN"},{"id":"T8066","span":{"begin":1312,"end":1317},"obj":"NNS"},{"id":"T8067","span":{"begin":1309,"end":1311},"obj":"NN"},{"id":"T8068","span":{"begin":1318,"end":1320},"obj":"VBZ"},{"id":"T8069","span":{"begin":1321,"end":1332},"obj":"RB"},{"id":"T8070","span":{"begin":1341,"end":1342},"obj":"-LRB-"},{"id":"T8071","span":{"begin":1349,"end":1351},"obj":"NN"},{"id":"T8072","span":{"begin":1342,"end":1348},"obj":"NN"},{"id":"T8073","span":{"begin":1351,"end":1352},"obj":"-RRB-"},{"id":"T8074","span":{"begin":1352,"end":1353},"obj":"."}],"relations":[{"id":"R5143","pred":"poss","subj":"T7743","obj":"T7744"},{"id":"R5144","pred":"nsubj","subj":"T7744","obj":"T7745"},{"id":"R5145","pred":"mark","subj":"T7746","obj":"T7747"},{"id":"R5146","pred":"ccomp","subj":"T7747","obj":"T7745"},{"id":"R5147","pred":"npadvmod","subj":"T7748","obj":"T7749"},{"id":"R5148","pred":"amod","subj":"T7749","obj":"T7751"},{"id":"R5149","pred":"punct","subj":"T7750","obj":"T7749"},{"id":"R5150","pred":"nsubjpass","subj":"T7751","obj":"T7747"},{"id":"R5151","pred":"amod","subj":"T7752","obj":"T7753"},{"id":"R5152","pred":"amod","subj":"T7753","obj":"T7751"},{"id":"R5153","pred":"punct","subj":"T7754","obj":"T7753"},{"id":"R5154","pred":"auxpass","subj":"T7755","obj":"T7747"},{"id":"R5155","pred":"prep","subj":"T7756","obj":"T7747"},{"id":"R5156","pred":"amod","subj":"T7757","obj":"T7758"},{"id":"R5157","pred":"pobj","subj":"T7758","obj":"T7756"},{"id":"R5158","pred":"cc","subj":"T7759","obj":"T7758"},{"id":"R5159","pred":"conj","subj":"T7760","obj":"T7758"},{"id":"R5160","pred":"prep","subj":"T7761","obj":"T7758"},{"id":"R5161","pred":"det","subj":"T7762","obj":"T7763"},{"id":"R5162","pred":"pobj","subj":"T7763","obj":"T7761"},{"id":"R5163","pred":"compound","subj":"T7764","obj":"T7763"},{"id":"R5164","pred":"punct","subj":"T7765","obj":"T7745"},{"id":"R5165","pred":"advmod","subj":"T7767","obj":"T7768"},{"id":"R5166","pred":"punct","subj":"T7769","obj":"T7768"},{"id":"R5167","pred":"nsubjpass","subj":"T7770","obj":"T7768"},{"id":"R5168","pred":"auxpass","subj":"T7771","obj":"T7768"},{"id":"R5169","pred":"neg","subj":"T7772","obj":"T7768"},{"id":"R5170","pred":"mark","subj":"T7773","obj":"T7774"},{"id":"R5171","pred":"ccomp","subj":"T7774","obj":"T7768"},{"id":"R5172","pred":"compound","subj":"T7775","obj":"T7776"},{"id":"R5173","pred":"nsubjpass","subj":"T7776","obj":"T7774"},{"id":"R5174","pred":"auxpass","subj":"T7777","obj":"T7774"},{"id":"R5175","pred":"prep","subj":"T7778","obj":"T7774"},{"id":"R5176","pred":"amod","subj":"T7779","obj":"T7780"},{"id":"R5177","pred":"pobj","subj":"T7780","obj":"T7778"},{"id":"R5178","pred":"prep","subj":"T7781","obj":"T7780"},{"id":"R5179","pred":"compound","subj":"T7782","obj":"T7783"},{"id":"R5180","pred":"pobj","subj":"T7783","obj":"T7781"},{"id":"R5181","pred":"punct","subj":"T7784","obj":"T7768"},{"id":"R5182","pred":"advmod","subj":"T7786","obj":"T7787"},{"id":"R5183","pred":"punct","subj":"T7788","obj":"T7787"},{"id":"R5184","pred":"nsubj","subj":"T7789","obj":"T7787"},{"id":"R5185","pred":"aux","subj":"T7790","obj":"T7787"},{"id":"R5186","pred":"mark","subj":"T7791","obj":"T7792"},{"id":"R5187","pred":"ccomp","subj":"T7792","obj":"T7787"},{"id":"R5188","pred":"det","subj":"T7793","obj":"T7794"},{"id":"R5189","pred":"nsubj","subj":"T7794","obj":"T7792"},{"id":"R5190","pred":"compound","subj":"T7795","obj":"T7794"},{"id":"R5191","pred":"prep","subj":"T7796","obj":"T7794"},{"id":"R5192","pred":"det","subj":"T7797","obj":"T7798"},{"id":"R5193","pred":"pobj","subj":"T7798","obj":"T7796"},{"id":"R5194","pred":"compound","subj":"T7799","obj":"T7798"},{"id":"R5195","pred":"poss","subj":"T7800","obj":"T7801"},{"id":"R5196","pred":"dobj","subj":"T7801","obj":"T7792"},{"id":"R5197","pred":"compound","subj":"T7802","obj":"T7801"},{"id":"R5198","pred":"punct","subj":"T7803","obj":"T7787"},{"id":"R5199","pred":"aux","subj":"T7805","obj":"T7806"},{"id":"R5200","pred":"advcl","subj":"T7806","obj":"T7807"},{"id":"R5201","pred":"det","subj":"T7808","obj":"T7809"},{"id":"R5202","pred":"dobj","subj":"T7809","obj":"T7806"},{"id":"R5203","pred":"punct","subj":"T7810","obj":"T7807"},{"id":"R5204","pred":"nsubj","subj":"T7811","obj":"T7807"},{"id":"R5205","pred":"det","subj":"T7812","obj":"T7813"},{"id":"R5206","pred":"dobj","subj":"T7813","obj":"T7807"},{"id":"R5207","pred":"prep","subj":"T7814","obj":"T7813"},{"id":"R5208","pred":"npadvmod","subj":"T7815","obj":"T7816"},{"id":"R5209","pred":"amod","subj":"T7816","obj":"T7818"},{"id":"R5210","pred":"punct","subj":"T7817","obj":"T7816"},{"id":"R5211","pred":"pobj","subj":"T7818","obj":"T7814"},{"id":"R5212","pred":"compound","subj":"T7819","obj":"T7820"},{"id":"R5213","pred":"compound","subj":"T7820","obj":"T7818"},{"id":"R5214","pred":"punct","subj":"T7821","obj":"T7820"},{"id":"R5215","pred":"punct","subj":"T7822","obj":"T7818"},{"id":"R5216","pred":"compound","subj":"T7823","obj":"T7824"},{"id":"R5217","pred":"appos","subj":"T7824","obj":"T7818"},{"id":"R5218","pred":"punct","subj":"T7825","obj":"T7824"},{"id":"R5219","pred":"punct","subj":"T7826","obj":"T7818"},{"id":"R5220","pred":"acl","subj":"T7827","obj":"T7818"},{"id":"R5221","pred":"amod","subj":"T7828","obj":"T7829"},{"id":"R5222","pred":"dobj","subj":"T7829","obj":"T7827"},{"id":"R5223","pred":"prep","subj":"T7830","obj":"T7807"},{"id":"R5224","pred":"det","subj":"T7831","obj":"T7832"},{"id":"R5225","pred":"pobj","subj":"T7832","obj":"T7830"},{"id":"R5226","pred":"compound","subj":"T7833","obj":"T7832"},{"id":"R5227","pred":"punct","subj":"T7834","obj":"T7807"},{"id":"R5228","pred":"nsubj","subj":"T7836","obj":"T7837"},{"id":"R5229","pred":"amod","subj":"T7838","obj":"T7839"},{"id":"R5230","pred":"dobj","subj":"T7839","obj":"T7837"},{"id":"R5231","pred":"prep","subj":"T7840","obj":"T7839"},{"id":"R5232","pred":"compound","subj":"T7841","obj":"T7842"},{"id":"R5233","pred":"pobj","subj":"T7842","obj":"T7840"},{"id":"R5234","pred":"prep","subj":"T7843","obj":"T7837"},{"id":"R5235","pred":"det","subj":"T7844","obj":"T7845"},{"id":"R5236","pred":"pobj","subj":"T7845","obj":"T7843"},{"id":"R5237","pred":"nummod","subj":"T7846","obj":"T7847"},{"id":"R5238","pred":"compound","subj":"T7847","obj":"T7845"},{"id":"R5239","pred":"punct","subj":"T7848","obj":"T7846"},{"id":"R5240","pred":"punct","subj":"T7849","obj":"T7847"},{"id":"R5241","pred":"punct","subj":"T7850","obj":"T7837"},{"id":"R5242","pred":"prep","subj":"T7852","obj":"T7853"},{"id":"R5243","pred":"compound","subj":"T7854","obj":"T7855"},{"id":"R5244","pred":"compound","subj":"T7855","obj":"T7856"},{"id":"R5245","pred":"pobj","subj":"T7856","obj":"T7852"},{"id":"R5246","pred":"punct","subj":"T7857","obj":"T7853"},{"id":"R5247","pred":"nsubj","subj":"T7858","obj":"T7853"},{"id":"R5248","pred":"punct","subj":"T7859","obj":"T7858"},{"id":"R5249","pred":"nummod","subj":"T7860","obj":"T7858"},{"id":"R5250","pred":"punct","subj":"T7861","obj":"T7858"},{"id":"R5251","pred":"nummod","subj":"T7862","obj":"T7858"},{"id":"R5252","pred":"prep","subj":"T7863","obj":"T7853"},{"id":"R5253","pred":"det","subj":"T7864","obj":"T7865"},{"id":"R5254","pred":"pobj","subj":"T7865","obj":"T7863"},{"id":"R5255","pred":"compound","subj":"T7866","obj":"T7867"},{"id":"R5256","pred":"compound","subj":"T7867","obj":"T7865"},{"id":"R5257","pred":"punct","subj":"T7868","obj":"T7867"},{"id":"R5258","pred":"prep","subj":"T7869","obj":"T7853"},{"id":"R5259","pred":"amod","subj":"T7870","obj":"T7871"},{"id":"R5260","pred":"pobj","subj":"T7871","obj":"T7869"},{"id":"R5261","pred":"punct","subj":"T7872","obj":"T7873"},{"id":"R5262","pred":"parataxis","subj":"T7873","obj":"T7871"},{"id":"R5263","pred":"compound","subj":"T7874","obj":"T7873"},{"id":"R5264","pred":"punct","subj":"T7875","obj":"T7873"},{"id":"R5265","pred":"punct","subj":"T7876","obj":"T7853"},{"id":"R5266","pred":"advcl","subj":"T7877","obj":"T7853"},{"id":"R5267","pred":"prep","subj":"T7878","obj":"T7877"},{"id":"R5268","pred":"det","subj":"T7879","obj":"T7880"},{"id":"R5269","pred":"pobj","subj":"T7880","obj":"T7878"},{"id":"R5270","pred":"mark","subj":"T7881","obj":"T7882"},{"id":"R5271","pred":"acl","subj":"T7882","obj":"T7880"},{"id":"R5272","pred":"det","subj":"T7883","obj":"T7884"},{"id":"R5273","pred":"nsubj","subj":"T7884","obj":"T7882"},{"id":"R5274","pred":"punct","subj":"T7885","obj":"T7884"},{"id":"R5275","pred":"nummod","subj":"T7886","obj":"T7884"},{"id":"R5276","pred":"punct","subj":"T7887","obj":"T7884"},{"id":"R5277","pred":"nummod","subj":"T7888","obj":"T7884"},{"id":"R5278","pred":"prep","subj":"T7889","obj":"T7882"},{"id":"R5279","pred":"amod","subj":"T7890","obj":"T7891"},{"id":"R5280","pred":"amod","subj":"T7891","obj":"T7893"},{"id":"R5281","pred":"punct","subj":"T7892","obj":"T7891"},{"id":"R5282","pred":"pobj","subj":"T7893","obj":"T7889"},{"id":"R5283","pred":"punct","subj":"T7894","obj":"T7853"},{"id":"R5284","pred":"advmod","subj":"T7896","obj":"T7897"},{"id":"R5285","pred":"punct","subj":"T7898","obj":"T7897"},{"id":"R5286","pred":"prep","subj":"T7899","obj":"T7897"},{"id":"R5287","pred":"compound","subj":"T7900","obj":"T7901"},{"id":"R5288","pred":"compound","subj":"T7901","obj":"T7902"},{"id":"R5289","pred":"pobj","subj":"T7902","obj":"T7899"},{"id":"R5290","pred":"punct","subj":"T7903","obj":"T7897"},{"id":"R5291","pred":"compound","subj":"T7904","obj":"T7905"},{"id":"R5292","pred":"nsubjpass","subj":"T7905","obj":"T7897"},{"id":"R5293","pred":"punct","subj":"T7906","obj":"T7905"},{"id":"R5294","pred":"punct","subj":"T7907","obj":"T7905"},{"id":"R5295","pred":"punct","subj":"T7908","obj":"T7909"},{"id":"R5296","pred":"appos","subj":"T7909","obj":"T7905"},{"id":"R5297","pred":"nmod","subj":"T7910","obj":"T7909"},{"id":"R5298","pred":"punct","subj":"T7911","obj":"T7909"},{"id":"R5299","pred":"punct","subj":"T7912","obj":"T7909"},{"id":"R5300","pred":"nummod","subj":"T7913","obj":"T7909"},{"id":"R5301","pred":"auxpass","subj":"T7914","obj":"T7897"},{"id":"R5302","pred":"advmod","subj":"T7915","obj":"T7897"},{"id":"R5303","pred":"agent","subj":"T7916","obj":"T7897"},{"id":"R5304","pred":"pobj","subj":"T7917","obj":"T7916"},{"id":"R5305","pred":"punct","subj":"T7918","obj":"T7917"},{"id":"R5306","pred":"nummod","subj":"T7919","obj":"T7917"},{"id":"R5307","pred":"punct","subj":"T7920","obj":"T7917"},{"id":"R5308","pred":"nummod","subj":"T7921","obj":"T7917"},{"id":"R5309","pred":"punct","subj":"T7922","obj":"T7897"},{"id":"R5310","pred":"cc","subj":"T7923","obj":"T7897"},{"id":"R5311","pred":"auxpass","subj":"T7924","obj":"T7925"},{"id":"R5312","pred":"conj","subj":"T7925","obj":"T7897"},{"id":"R5313","pred":"advmod","subj":"T7926","obj":"T7925"},{"id":"R5314","pred":"agent","subj":"T7927","obj":"T7925"},{"id":"R5315","pred":"compound","subj":"T7928","obj":"T7929"},{"id":"R5316","pred":"pobj","subj":"T7929","obj":"T7927"},{"id":"R5317","pred":"compound","subj":"T7930","obj":"T7931"},{"id":"R5318","pred":"compound","subj":"T7931","obj":"T7929"},{"id":"R5319","pred":"punct","subj":"T7932","obj":"T7931"},{"id":"R5320","pred":"compound","subj":"T7933","obj":"T7929"},{"id":"R5321","pred":"punct","subj":"T7934","obj":"T7935"},{"id":"R5322","pred":"parataxis","subj":"T7935","obj":"T7925"},{"id":"R5323","pred":"compound","subj":"T7936","obj":"T7935"},{"id":"R5324","pred":"punct","subj":"T7937","obj":"T7935"},{"id":"R5325","pred":"punct","subj":"T7938","obj":"T7897"},{"id":"R5326","pred":"advmod","subj":"T7940","obj":"T7941"},{"id":"R5327","pred":"advcl","subj":"T7941","obj":"T7946"},{"id":"R5328","pred":"nsubjpass","subj":"T7942","obj":"T7941"},{"id":"R5329","pred":"cc","subj":"T7943","obj":"T7942"},{"id":"R5330","pred":"conj","subj":"T7944","obj":"T7942"},{"id":"R5331","pred":"auxpass","subj":"T7945","obj":"T7941"},{"id":"R5332","pred":"prep","subj":"T7947","obj":"T7941"},{"id":"R5333","pred":"det","subj":"T7948","obj":"T7949"},{"id":"R5334","pred":"pobj","subj":"T7949","obj":"T7947"},{"id":"R5335","pred":"amod","subj":"T7950","obj":"T7949"},{"id":"R5336","pred":"punct","subj":"T7951","obj":"T7952"},{"id":"R5337","pred":"parataxis","subj":"T7952","obj":"T7949"},{"id":"R5338","pred":"prep","subj":"T7953","obj":"T7952"},{"id":"R5339","pred":"pobj","subj":"T7954","obj":"T7953"},{"id":"R5340","pred":"cc","subj":"T7955","obj":"T7954"},{"id":"R5341","pred":"conj","subj":"T7956","obj":"T7954"},{"id":"R5342","pred":"punct","subj":"T7957","obj":"T7952"},{"id":"R5343","pred":"punct","subj":"T7958","obj":"T7946"},{"id":"R5344","pred":"det","subj":"T7959","obj":"T7960"},{"id":"R5345","pred":"nsubj","subj":"T7960","obj":"T7946"},{"id":"R5346","pred":"prep","subj":"T7961","obj":"T7960"},{"id":"R5347","pred":"pobj","subj":"T7962","obj":"T7961"},{"id":"R5348","pred":"punct","subj":"T7963","obj":"T7964"},{"id":"R5349","pred":"dobj","subj":"T7964","obj":"T7946"},{"id":"R5350","pred":"nmod","subj":"T7965","obj":"T7966"},{"id":"R5351","pred":"nmod","subj":"T7966","obj":"T7964"},{"id":"R5352","pred":"punct","subj":"T7967","obj":"T7966"},{"id":"R5353","pred":"punct","subj":"T7968","obj":"T7964"},{"id":"R5354","pred":"punct","subj":"T7969","obj":"T7964"},{"id":"R5355","pred":"nmod","subj":"T7970","obj":"T7964"},{"id":"R5356","pred":"punct","subj":"T7971","obj":"T7964"},{"id":"R5357","pred":"punct","subj":"T7972","obj":"T7964"},{"id":"R5358","pred":"nummod","subj":"T7973","obj":"T7964"},{"id":"R5359","pred":"cc","subj":"T7974","obj":"T7964"},{"id":"R5360","pred":"nmod","subj":"T7975","obj":"T7976"},{"id":"R5361","pred":"nmod","subj":"T7976","obj":"T7978"},{"id":"R5362","pred":"punct","subj":"T7977","obj":"T7976"},{"id":"R5363","pred":"conj","subj":"T7978","obj":"T7964"},{"id":"R5364","pred":"punct","subj":"T7979","obj":"T7978"},{"id":"R5365","pred":"punct","subj":"T7980","obj":"T7978"},{"id":"R5366","pred":"nmod","subj":"T7981","obj":"T7978"},{"id":"R5367","pred":"punct","subj":"T7982","obj":"T7978"},{"id":"R5368","pred":"punct","subj":"T7983","obj":"T7978"},{"id":"R5369","pred":"nummod","subj":"T7984","obj":"T7978"},{"id":"R5370","pred":"punct","subj":"T7985","obj":"T7946"},{"id":"R5371","pred":"punct","subj":"T7986","obj":"T7946"},{"id":"R5372","pred":"det","subj":"T7988","obj":"T7989"},{"id":"R5373","pred":"nsubjpass","subj":"T7989","obj":"T7990"},{"id":"R5374","pred":"prep","subj":"T7991","obj":"T7989"},{"id":"R5375","pred":"pobj","subj":"T7992","obj":"T7991"},{"id":"R5376","pred":"auxpass","subj":"T7993","obj":"T7990"},{"id":"R5377","pred":"advmod","subj":"T7994","obj":"T7990"},{"id":"R5378","pred":"prep","subj":"T7995","obj":"T7990"},{"id":"R5379","pred":"det","subj":"T7996","obj":"T7997"},{"id":"R5380","pred":"pobj","subj":"T7997","obj":"T7995"},{"id":"R5381","pred":"prep","subj":"T7998","obj":"T7997"},{"id":"R5382","pred":"compound","subj":"T7999","obj":"T8000"},{"id":"R5383","pred":"pobj","subj":"T8000","obj":"T7998"},{"id":"R5384","pred":"prep","subj":"T8001","obj":"T8000"},{"id":"R5385","pred":"det","subj":"T8002","obj":"T8003"},{"id":"R5386","pred":"pobj","subj":"T8003","obj":"T8001"},{"id":"R5387","pred":"compound","subj":"T8004","obj":"T8003"},{"id":"R5388","pred":"punct","subj":"T8005","obj":"T8006"},{"id":"R5389","pred":"appos","subj":"T8006","obj":"T8000"},{"id":"R5390","pred":"nmod","subj":"T8007","obj":"T8008"},{"id":"R5391","pred":"nmod","subj":"T8008","obj":"T8006"},{"id":"R5392","pred":"punct","subj":"T8009","obj":"T8008"},{"id":"R5393","pred":"punct","subj":"T8010","obj":"T8006"},{"id":"R5394","pred":"punct","subj":"T8011","obj":"T8006"},{"id":"R5395","pred":"nmod","subj":"T8012","obj":"T8006"},{"id":"R5396","pred":"punct","subj":"T8013","obj":"T8006"},{"id":"R5397","pred":"punct","subj":"T8014","obj":"T8006"},{"id":"R5398","pred":"nummod","subj":"T8015","obj":"T8006"},{"id":"R5399","pred":"punct","subj":"T8016","obj":"T8006"},{"id":"R5400","pred":"nmod","subj":"T8017","obj":"T8018"},{"id":"R5401","pred":"nmod","subj":"T8018","obj":"T8020"},{"id":"R5402","pred":"punct","subj":"T8019","obj":"T8018"},{"id":"R5403","pred":"conj","subj":"T8020","obj":"T8006"},{"id":"R5404","pred":"punct","subj":"T8021","obj":"T8020"},{"id":"R5405","pred":"punct","subj":"T8022","obj":"T8020"},{"id":"R5406","pred":"nmod","subj":"T8023","obj":"T8020"},{"id":"R5407","pred":"punct","subj":"T8024","obj":"T8020"},{"id":"R5408","pred":"punct","subj":"T8025","obj":"T8020"},{"id":"R5409","pred":"nummod","subj":"T8026","obj":"T8020"},{"id":"R5410","pred":"punct","subj":"T8027","obj":"T8020"},{"id":"R5411","pred":"nmod","subj":"T8028","obj":"T8029"},{"id":"R5412","pred":"nmod","subj":"T8029","obj":"T8031"},{"id":"R5413","pred":"punct","subj":"T8030","obj":"T8029"},{"id":"R5414","pred":"conj","subj":"T8031","obj":"T8020"},{"id":"R5415","pred":"punct","subj":"T8032","obj":"T8031"},{"id":"R5416","pred":"punct","subj":"T8033","obj":"T8031"},{"id":"R5417","pred":"nmod","subj":"T8034","obj":"T8031"},{"id":"R5418","pred":"punct","subj":"T8035","obj":"T8031"},{"id":"R5419","pred":"punct","subj":"T8036","obj":"T8031"},{"id":"R5420","pred":"nummod","subj":"T8037","obj":"T8031"},{"id":"R5421","pred":"cc","subj":"T8038","obj":"T8031"},{"id":"R5422","pred":"nmod","subj":"T8039","obj":"T8040"},{"id":"R5423","pred":"nmod","subj":"T8040","obj":"T8042"},{"id":"R5424","pred":"punct","subj":"T8041","obj":"T8040"},{"id":"R5425","pred":"conj","subj":"T8042","obj":"T8031"},{"id":"R5426","pred":"punct","subj":"T8043","obj":"T8042"},{"id":"R5427","pred":"punct","subj":"T8044","obj":"T8042"},{"id":"R5428","pred":"nmod","subj":"T8045","obj":"T8042"},{"id":"R5429","pred":"punct","subj":"T8046","obj":"T8042"},{"id":"R5430","pred":"punct","subj":"T8047","obj":"T8042"},{"id":"R5431","pred":"nummod","subj":"T8048","obj":"T8042"},{"id":"R5432","pred":"punct","subj":"T8049","obj":"T8050"},{"id":"R5433","pred":"parataxis","subj":"T8050","obj":"T7990"},{"id":"R5434","pred":"compound","subj":"T8051","obj":"T8050"},{"id":"R5435","pred":"punct","subj":"T8052","obj":"T8050"},{"id":"R5436","pred":"punct","subj":"T8053","obj":"T7990"},{"id":"R5437","pred":"nsubj","subj":"T8055","obj":"T8056"},{"id":"R5438","pred":"mark","subj":"T8057","obj":"T8058"},{"id":"R5439","pred":"ccomp","subj":"T8058","obj":"T8056"},{"id":"R5440","pred":"det","subj":"T8059","obj":"T8060"},{"id":"R5441","pred":"nsubjpass","subj":"T8060","obj":"T8058"},{"id":"R5442","pred":"compound","subj":"T8061","obj":"T8060"},{"id":"R5443","pred":"acl","subj":"T8062","obj":"T8060"},{"id":"R5444","pred":"punct","subj":"T8063","obj":"T8064"},{"id":"R5445","pred":"nummod","subj":"T8064","obj":"T8065"},{"id":"R5446","pred":"compound","subj":"T8065","obj":"T8066"},{"id":"R5447","pred":"dobj","subj":"T8066","obj":"T8062"},{"id":"R5448","pred":"compound","subj":"T8067","obj":"T8066"},{"id":"R5449","pred":"auxpass","subj":"T8068","obj":"T8058"},{"id":"R5450","pred":"advmod","subj":"T8069","obj":"T8058"},{"id":"R5451","pred":"punct","subj":"T8070","obj":"T8071"},{"id":"R5452","pred":"parataxis","subj":"T8071","obj":"T8058"},{"id":"R5453","pred":"compound","subj":"T8072","obj":"T8071"},{"id":"R5454","pred":"punct","subj":"T8073","obj":"T8071"},{"id":"R5455","pred":"punct","subj":"T8074","obj":"T8056"}],"text":"Our results indicate that thymine-rich single-stranded DNA is required for initial loading and activation of the Mcm helicase. However, it is not known whether thymine sequences are required for processive unwinding of duplex DNA. Therefore, we have examined whether the nucleotide composition of the duplex region affects its unwinding activity. To address this issue, we constructed a series of T-tailed Y-fork structures (T-fork) containing various sequences in the duplex segment. They carried varied contents of cytosine residues on the 3′-tail strand. In gel shift assays, Mcm4/6/7 bound to these Y-fork substrates with identical affinity (Figure 8A), consistent with the notion that the Mcm4/6/7 binds to single-stranded tails. However, in DNA helicase assays, T-fork/(C:G)49 was hardly displaced by Mcm4/6/7, but was readily displaced by SV40 T-antigen DNA helicase (Figure 8B). When thymine or adenine is inserted as every third nucleotide (repeats of CCT or CCA), the extent of unwinding increased (T-fork/(CCT:GGA)16 and T-fork/(CCA:GGT)16). The efficiency of unwinding is roughly correlated with the content of GC pairs in the duplex segment [T-fork/(CCAA:GGTT)12, T-fork/(CCTT:GGAA)12, T-fork/(CAAA:GTTT)12 and T-fork/(CTTT:GAAA)12; Figure 8B]. It appears that the duplex segment containing \u003c50% GC pairs is efficiently unwound (Figure 8C)."}

{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T7604","span":{"begin":26,"end":33},"obj":"CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group"},{"id":"T7605","span":{"begin":39,"end":58},"obj":"CHEBI_SO_EXT:single_stranded_DNA"},{"id":"T7606","span":{"begin":113,"end":116},"obj":"GO:0042555"},{"id":"T7607","span":{"begin":117,"end":125},"obj":"GO_EXT:0004386"},{"id":"T7608","span":{"begin":160,"end":167},"obj":"CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group"},{"id":"T7609","span":{"begin":168,"end":177},"obj":"SO_EXT:biological_sequence"},{"id":"T7610","span":{"begin":206,"end":229},"obj":"GO:0032508"},{"id":"T7611","span":{"begin":219,"end":229},"obj":"CHEBI_SO_EXT:double_stranded_DNA"},{"id":"T7612","span":{"begin":271,"end":281},"obj":"CHEBI_SO_EXT:nucleotide"},{"id":"T7613","span":{"begin":301,"end":307},"obj":"SO:0000985"},{"id":"T7614","span":{"begin":408,"end":412},"obj":"GO:0005657"},{"id":"T7615","span":{"begin":427,"end":431},"obj":"GO:0005657"},{"id":"T7616","span":{"begin":452,"end":461},"obj":"SO_EXT:biological_sequence"},{"id":"T7617","span":{"begin":469,"end":475},"obj":"SO:0000985"},{"id":"T7618","span":{"begin":517,"end":525},"obj":"CHEBI_EXT:cytosine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group"},{"id":"T7619","span":{"begin":526,"end":534},"obj":"CHEBI_EXT:residue"},{"id":"T7620","span":{"begin":579,"end":583},"obj":"PR_EXT:000010246"},{"id":"T7621","span":{"begin":579,"end":587},"obj":"GO:0097373"},{"id":"T7622","span":{"begin":588,"end":593},"obj":"CHEMINF_GO_EXT:chemical_binding_or_bond_formation"},{"id":"T7623","span":{"begin":605,"end":609},"obj":"GO:0005657"},{"id":"T7624","span":{"begin":694,"end":698},"obj":"PR_EXT:000010246"},{"id":"T7625","span":{"begin":694,"end":702},"obj":"GO:0097373"},{"id":"T7626","span":{"begin":703,"end":708},"obj":"CHEMINF_GO_EXT:chemical_binding_or_bond_formation"},{"id":"T7627","span":{"begin":712,"end":727},"obj":"SO:0000984"},{"id":"T7628","span":{"begin":747,"end":750},"obj":"CHEBI_SO_EXT:DNA"},{"id":"T7629","span":{"begin":747,"end":759},"obj":"GO_EXT:0003678"},{"id":"T7630","span":{"begin":770,"end":774},"obj":"GO:0005657"},{"id":"T7631","span":{"begin":807,"end":811},"obj":"PR_EXT:000010246"},{"id":"T7632","span":{"begin":807,"end":815},"obj":"GO:0097373"},{"id":"T7633","span":{"begin":846,"end":850},"obj":"NCBITaxon:10633"},{"id":"T7634","span":{"begin":853,"end":860},"obj":"CHEBI_EXT:59132"},{"id":"T7635","span":{"begin":861,"end":864},"obj":"CHEBI_SO_EXT:DNA"},{"id":"T7636","span":{"begin":861,"end":873},"obj":"GO_EXT:0003678"},{"id":"T7637","span":{"begin":892,"end":899},"obj":"CHEBI_EXT:thymine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group"},{"id":"T7638","span":{"begin":903,"end":910},"obj":"CHEBI_EXT:adenine_nucleobase_or_nucleoside_or_nucleotide_molecular_entity_or_group"},{"id":"T7639","span":{"begin":914,"end":922},"obj":"SO_EXT:sequence_insertion_process"},{"id":"T7640","span":{"begin":938,"end":948},"obj":"CHEBI_SO_EXT:nucleotide"},{"id":"T7641","span":{"begin":950,"end":957},"obj":"SO_EXT:sequence_repeat_unit_or_region"},{"id":"T7642","span":{"begin":1011,"end":1015},"obj":"GO:0005657"},{"id":"T7643","span":{"begin":1034,"end":1038},"obj":"GO:0005657"},{"id":"T7644","span":{"begin":1139,"end":1145},"obj":"SO:0000985"},{"id":"T7645","span":{"begin":1157,"end":1161},"obj":"GO:0005657"},{"id":"T7646","span":{"begin":1179,"end":1183},"obj":"GO:0005657"},{"id":"T7647","span":{"begin":1201,"end":1205},"obj":"GO:0005657"},{"id":"T7648","span":{"begin":1226,"end":1230},"obj":"GO:0005657"},{"id":"T7649","span":{"begin":1278,"end":1284},"obj":"SO:0000985"}],"text":"Our results indicate that thymine-rich single-stranded DNA is required for initial loading and activation of the Mcm helicase. However, it is not known whether thymine sequences are required for processive unwinding of duplex DNA. Therefore, we have examined whether the nucleotide composition of the duplex region affects its unwinding activity. To address this issue, we constructed a series of T-tailed Y-fork structures (T-fork) containing various sequences in the duplex segment. They carried varied contents of cytosine residues on the 3′-tail strand. In gel shift assays, Mcm4/6/7 bound to these Y-fork substrates with identical affinity (Figure 8A), consistent with the notion that the Mcm4/6/7 binds to single-stranded tails. However, in DNA helicase assays, T-fork/(C:G)49 was hardly displaced by Mcm4/6/7, but was readily displaced by SV40 T-antigen DNA helicase (Figure 8B). When thymine or adenine is inserted as every third nucleotide (repeats of CCT or CCA), the extent of unwinding increased (T-fork/(CCT:GGA)16 and T-fork/(CCA:GGT)16). The efficiency of unwinding is roughly correlated with the content of GC pairs in the duplex segment [T-fork/(CCAA:GGTT)12, T-fork/(CCTT:GGAA)12, T-fork/(CAAA:GTTT)12 and T-fork/(CTTT:GAAA)12; Figure 8B]. It appears that the duplex segment containing \u003c50% GC pairs is efficiently unwound (Figure 8C)."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T7533","span":{"begin":39,"end":54},"obj":"SO:0000984"},{"id":"T7534","span":{"begin":113,"end":116},"obj":"GO:0042555"},{"id":"T7535","span":{"begin":206,"end":229},"obj":"GO:0032508"},{"id":"T7536","span":{"begin":219,"end":225},"obj":"SO:0000985"},{"id":"T7537","span":{"begin":301,"end":307},"obj":"SO:0000985"},{"id":"T7538","span":{"begin":408,"end":412},"obj":"GO:0005657"},{"id":"T7539","span":{"begin":427,"end":431},"obj":"GO:0005657"},{"id":"T7540","span":{"begin":469,"end":475},"obj":"SO:0000985"},{"id":"T7541","span":{"begin":579,"end":583},"obj":"PR:000010246"},{"id":"T7542","span":{"begin":579,"end":587},"obj":"GO:0097373"},{"id":"T7543","span":{"begin":605,"end":609},"obj":"GO:0005657"},{"id":"T7544","span":{"begin":694,"end":698},"obj":"PR:000010246"},{"id":"T7545","span":{"begin":694,"end":702},"obj":"GO:0097373"},{"id":"T7546","span":{"begin":712,"end":727},"obj":"SO:0000984"},{"id":"T7547","span":{"begin":770,"end":774},"obj":"GO:0005657"},{"id":"T7548","span":{"begin":807,"end":811},"obj":"PR:000010246"},{"id":"T7549","span":{"begin":807,"end":815},"obj":"GO:0097373"},{"id":"T7550","span":{"begin":846,"end":850},"obj":"NCBITaxon:10633"},{"id":"T7551","span":{"begin":853,"end":860},"obj":"CHEBI:59132"},{"id":"T7552","span":{"begin":1011,"end":1015},"obj":"GO:0005657"},{"id":"T7553","span":{"begin":1034,"end":1038},"obj":"GO:0005657"},{"id":"T7554","span":{"begin":1139,"end":1145},"obj":"SO:0000985"},{"id":"T7555","span":{"begin":1157,"end":1161},"obj":"GO:0005657"},{"id":"T7556","span":{"begin":1179,"end":1183},"obj":"GO:0005657"},{"id":"T7557","span":{"begin":1201,"end":1205},"obj":"GO:0005657"},{"id":"T7558","span":{"begin":1226,"end":1230},"obj":"GO:0005657"},{"id":"T7559","span":{"begin":1278,"end":1284},"obj":"SO:0000985"}],"text":"Our results indicate that thymine-rich single-stranded DNA is required for initial loading and activation of the Mcm helicase. However, it is not known whether thymine sequences are required for processive unwinding of duplex DNA. Therefore, we have examined whether the nucleotide composition of the duplex region affects its unwinding activity. To address this issue, we constructed a series of T-tailed Y-fork structures (T-fork) containing various sequences in the duplex segment. They carried varied contents of cytosine residues on the 3′-tail strand. In gel shift assays, Mcm4/6/7 bound to these Y-fork substrates with identical affinity (Figure 8A), consistent with the notion that the Mcm4/6/7 binds to single-stranded tails. However, in DNA helicase assays, T-fork/(C:G)49 was hardly displaced by Mcm4/6/7, but was readily displaced by SV40 T-antigen DNA helicase (Figure 8B). When thymine or adenine is inserted as every third nucleotide (repeats of CCT or CCA), the extent of unwinding increased (T-fork/(CCT:GGA)16 and T-fork/(CCA:GGT)16). The efficiency of unwinding is roughly correlated with the content of GC pairs in the duplex segment [T-fork/(CCAA:GGTT)12, T-fork/(CCTT:GGAA)12, T-fork/(CAAA:GTTT)12 and T-fork/(CTTT:GAAA)12; Figure 8B]. It appears that the duplex segment containing \u003c50% GC pairs is efficiently unwound (Figure 8C)."}