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PMC:1134658 / 11508-22156 JSONTXT

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pmc-enju-pas

Id Subject Object Predicate Lexical cue
T7965 11-17 JJ denotes Recent
T7966 18-25 NN denotes studies
T7967 26-30 VB denotes have
T7968 31-43 VB denotes demonstrated
T7969 44-46 DT denotes an
T7970 47-56 JJ denotes important
T7971 57-61 NN denotes role
T7972 62-65 IN denotes for
T7973 66-69 NN denotes BMP
T7974 70-81 NN denotes superfamily
T7975 82-89 NN denotes members
T7976 90-92 IN denotes in
T7977 93-106 JJ denotes hematopoietic
T7978 107-111 NN denotes stem
T7979 112-117 NN denotes cells
T7980 117-118 -COMMA- denotes ,
T7981 119-124 JJ denotes early
T7982 125-135 NN denotes thymocytes
T7983 136-137 -LRB- denotes [
T7984 137-140 CD denotes 6,7
T7985 140-141 -RRB- denotes ]
T7986 142-145 CC denotes and
T7987 146-152 NN denotes B-cell
T7988 153-165 NN denotes malignancies
T7989 166-167 -LRB- denotes [
T7990 167-174 CD denotes 8,11,12
T7991 174-175 -RRB- denotes ]
T7992 175-176 -COMMA- denotes ,
T7993 177-180 CC denotes but
T7994 181-182 DT denotes a
T7995 183-187 NN denotes role
T7996 188-191 IN denotes for
T7997 192-196 NN denotes BMPs
T7998 197-199 IN denotes in
T7999 200-206 JJ denotes normal
T8000 207-212 JJ denotes human
T8001 213-214 NN denotes B
T8002 215-220 NN denotes cells
T8003 221-224 VB denotes has
T8004 225-235 RB denotes previously
T8005 236-239 RB denotes not
T8006 240-244 VB denotes been
T8007 245-253 VB denotes reported
T8008 255-258 DT denotes The
T8009 259-266 JJ denotes present
T8010 267-272 NN denotes study
T8011 273-285 VB denotes demonstrated
T8012 286-287 DT denotes a
T8013 288-299 JJ denotes significant
T8014 300-317 JJ denotes antiproliferative
T8015 318-324 NN denotes effect
T8016 325-327 IN denotes of
T8017 328-333 NN denotes BMP-6
T8018 334-336 IN denotes in
T8019 337-347 JJ denotes peripheral
T8020 348-353 NN denotes blood
T8021 354-359 JJ denotes CD19+
T8022 360-361 NN denotes B
T8023 362-367 NN denotes cells
T8024 369-381 RB denotes Additionally
T8025 381-382 -COMMA- denotes ,
T8026 383-388 NN denotes BMP-6
T8027 389-396 VB denotes induced
T8028 397-401 NN denotes cell
T8029 402-407 NN denotes death
T8030 408-410 IN denotes in
T8031 411-416 JJ denotes CD27+
T8032 417-423 NN denotes memory
T8033 424-425 NN denotes B
T8034 426-431 NN denotes cells
T8035 432-434 RB denotes as
T8036 435-439 RB denotes well
T8037 440-442 IN denotes as
T8038 443-445 IN denotes in
T8039 446-447 DT denotes a
T8040 448-455 NN denotes Burkitt
T8041 456-464 NN denotes lymphoma
T8042 465-469 NN denotes cell
T8043 470-474 NN denotes line
T8044 475-476 -LRB- denotes (
T8045 476-481 NN denotes Ramos
T8046 481-482 -RRB- denotes )
T8047 484-495 RB denotes Importantly
T8048 495-496 -COMMA- denotes ,
T8049 497-502 NN denotes BMP-6
T8050 503-510 VB denotes induced
T8051 511-512 DT denotes a
T8052 513-518 JJ denotes rapid
T8053 519-522 CC denotes and
T8054 523-529 JJ denotes marked
T8055 530-538 NN denotes increase
T8056 539-541 IN denotes in
T8057 542-552 NN denotes Smad-1/5/8
T8058 553-568 NN denotes phosphorylation
T8059 570-581 RB denotes Furthermore
T8060 581-582 -COMMA- denotes ,
T8061 583-586 DT denotes the
T8062 587-592 NN denotes BMP-6
T8063 593-600 VB denotes induced
T8064 601-605 NN denotes Smad
T8065 606-621 NN denotes phosphorylation
T8066 622-625 VB denotes was
T8067 626-634 VB denotes followed
T8068 635-637 IN denotes by
T8069 638-639 DT denotes a
T8070 640-649 JJ denotes selective
T8071 650-662 NN denotes upregulation
T8072 663-665 IN denotes of
T8073 666-669 NN denotes Id1
T8074 670-674 NN denotes mRNA
T8075 675-678 CC denotes and
T8076 679-689 JJ denotes subsequent
T8077 690-693 NN denotes Id1
T8078 694-701 NN denotes protein
T8079 703-705 IN denotes In
T8080 706-709 DT denotes the
T8081 710-717 JJ denotes present
T8082 718-723 NN denotes study
T8083 723-724 -COMMA- denotes ,
T8084 725-728 DT denotes the
T8085 729-741 VB denotes demonstrated
T8086 742-759 JJ denotes antiproliferative
T8087 760-766 NN denotes effect
T8088 767-769 IN denotes of
T8089 770-775 NN denotes BMP-6
T8090 776-778 IN denotes in
T8091 779-787 JJ denotes anti-IgM
T8092 788-795 VB denotes treated
T8093 796-797 NN denotes B
T8094 798-803 NN denotes cells
T8095 804-807 VB denotes was
T8096 808-819 JJ denotes significant
T8097 820-823 CC denotes and
T8098 824-838 JJ denotes dose-dependent
T8099 840-851 RB denotes Importantly
T8100 851-852 -COMMA- denotes ,
T8101 853-856 DT denotes the
T8102 857-875 JJ denotes anti-proliferative
T8103 876-882 NN denotes effect
T8104 883-885 IN denotes of
T8105 886-891 NN denotes BMP-6
T8106 892-897 MD denotes could
T8107 898-900 VB denotes be
T8108 901-911 RB denotes completely
T8109 912-923 VB denotes neutralized
T8110 924-926 IN denotes by
T8111 927-930 DT denotes the
T8112 931-934 NN denotes use
T8113 935-937 IN denotes of
T8114 938-939 DT denotes a
T8115 940-947 JJ denotes natural
T8116 948-957 NN denotes inhibitor
T8117 957-958 -COMMA- denotes ,
T8118 959-966 NNP denotes Noggin.
T8119 967-971 DT denotes This
T8120 972-974 VB denotes is
T8121 975-977 IN denotes in
T8122 978-982 NN denotes line
T8123 983-987 IN denotes with
T8124 988-994 NN denotes others
T8125 994-995 -COMMA- denotes ,
T8126 996-1003 VB denotes showing
T8127 1004-1008 IN denotes that
T8128 1009-1015 NN denotes Noggin
T8129 1016-1019 MD denotes can
T8130 1020-1028 VB denotes function
T8131 1029-1031 IN denotes as
T8132 1032-1033 DT denotes a
T8133 1034-1039 JJ denotes BMP-6
T8134 1040-1050 NN denotes antagonist
T8135 1051-1052 -LRB- denotes [
T8136 1052-1057 CD denotes 21,22
T8137 1057-1058 -RRB- denotes ]
T8138 1060-1062 IN denotes In
T8139 1063-1071 NN denotes addition
T8140 1071-1072 -COMMA- denotes ,
T8141 1073-1076 DT denotes the
T8142 1077-1088 NN denotes combination
T8143 1089-1091 IN denotes of
T8144 1092-1099 JJ denotes soluble
T8145 1100-1110 NN denotes BMP-RIB-Fc
T8146 1111-1114 CC denotes and
T8147 1115-1125 NN denotes BMP-RII-Fc
T8148 1126-1132 NN denotes fusion
T8149 1133-1141 NN denotes proteins
T8150 1142-1146 RB denotes also
T8151 1147-1158 VB denotes neutralized
T8152 1159-1162 DT denotes the
T8153 1163-1181 JJ denotes anti-proliferative
T8154 1182-1188 NN denotes effect
T8155 1189-1191 IN denotes of
T8156 1192-1197 NN denotes BMP-6
T8157 1198-1200 IN denotes in
T8158 1201-1206 JJ denotes human
T8159 1207-1208 NN denotes B
T8160 1209-1214 NN denotes cells
T8161 1216-1229 RB denotes Interestingly
T8162 1229-1230 -COMMA- denotes ,
T8163 1231-1233 IN denotes as
T8164 1234-1237 IN denotes for
T8165 1238-1243 JJ denotes other
T8166 1244-1247 NN denotes TGF
T8167 1248-1254 NN denotes family
T8168 1255-1262 NN denotes members
T8169 1262-1263 -COMMA- denotes ,
T8170 1264-1276 JJ denotes bifunctional
T8171 1277-1284 NN denotes effects
T8172 1285-1289 VB denotes have
T8173 1290-1294 RB denotes also
T8174 1295-1299 VB denotes been
T8175 1300-1312 VB denotes demonstrated
T8176 1313-1316 IN denotes for
T8177 1317-1321 NN denotes BMPs
T8178 1323-1330 IN denotes Whereas
T8179 1331-1338 JJ denotes several
T8180 1339-1341 IN denotes of
T8181 1342-1345 DT denotes the
T8182 1346-1350 NN denotes BMPs
T8183 1351-1355 VB denotes have
T8184 1356-1360 VB denotes been
T8185 1361-1366 VB denotes shown
T8186 1367-1369 TO denotes to
T8187 1370-1377 VB denotes promote
T8188 1378-1391 NN denotes proliferation
T8189 1392-1394 IN denotes in
T8190 1395-1402 JJ denotes various
T8191 1403-1407 NN denotes cell
T8192 1408-1413 NN denotes types
T8193 1414-1423 VB denotes including
T8194 1424-1435 NN denotes condrocytes
T8195 1436-1437 -LRB- denotes [
T8196 1437-1439 CD denotes 23
T8197 1439-1440 -RRB- denotes ]
T8198 1440-1441 -COMMA- denotes ,
T8199 1442-1447 NN denotes liver
T8200 1448-1449 -LRB- denotes [
T8201 1449-1451 CD denotes 24
T8202 1451-1452 -RRB- denotes ]
T8203 1453-1456 CC denotes and
T8204 1457-1466 NN denotes granulosa
T8205 1467-1472 NN denotes cells
T8206 1473-1474 -LRB- denotes [
T8207 1474-1476 CD denotes 25
T8208 1476-1477 -RRB- denotes ]
T8209 1477-1478 -COMMA- denotes ,
T8210 1479-1496 JJ denotes antiproliferative
T8211 1497-1504 NN denotes effects
T8212 1505-1508 CC denotes and
T8213 1509-1518 NN denotes induction
T8214 1519-1521 IN denotes of
T8215 1522-1531 NN denotes apoptosis
T8216 1532-1535 VB denotes has
T8217 1536-1540 VB denotes been
T8218 1541-1549 VB denotes reported
T8219 1550-1553 IN denotes for
T8220 1554-1555 NN denotes B
T8221 1556-1559 CC denotes and
T8222 1560-1561 NN denotes T
T8223 1562-1569 NN denotes lineage
T8224 1570-1575 NN denotes cells
T8225 1577-1584 JJ denotes Similar
T8226 1585-1592 NN denotes effects
T8227 1593-1595 IN denotes as
T8228 1596-1608 VB denotes demonstrated
T8229 1609-1612 IN denotes for
T8230 1613-1618 NN denotes BMP-6
T8231 1619-1621 IN denotes on
T8232 1622-1627 JJ denotes human
T8233 1628-1629 NN denotes B
T8234 1630-1635 NN denotes cells
T8235 1636-1638 IN denotes in
T8236 1639-1642 DT denotes the
T8237 1643-1650 JJ denotes present
T8238 1651-1656 NN denotes study
T8239 1656-1657 -COMMA- denotes ,
T8240 1658-1662 VB denotes were
T8241 1663-1675 VB denotes demonstrated
T8242 1676-1679 IN denotes for
T8243 1680-1685 NN denotes BMP-2
T8244 1685-1686 -COMMA- denotes ,
T8245 1687-1688 CD denotes 4
T8246 1688-1689 -COMMA- denotes ,
T8247 1690-1691 CD denotes 6
T8248 1692-1695 CC denotes and
T8249 1696-1698 CD denotes -7
T8250 1699-1701 IN denotes in
T8251 1702-1707 JJ denotes human
T8252 1708-1715 NN denotes myeloma
T8253 1716-1721 NN denotes cells
T8254 1722-1723 -LRB- denotes [
T8255 1723-1727 CD denotes 9-11
T8256 1727-1728 -RRB- denotes ]
T8257 1730-1735 JJ denotes Other
T8258 1736-1743 NN denotes members
T8259 1744-1746 IN denotes of
T8260 1747-1750 DT denotes the
T8261 1751-1761 NN denotes BMP-family
T8262 1762-1766 VB denotes have
T8263 1767-1771 RB denotes also
T8264 1772-1776 VB denotes been
T8265 1777-1785 VB denotes reported
T8266 1786-1788 TO denotes to
T8267 1789-1795 VB denotes induce
T8268 1796-1805 NN denotes apoptosis
T8269 1805-1806 -COMMA- denotes ,
T8270 1807-1816 VB denotes including
T8271 1817-1819 IN denotes in
T8272 1820-1825 NN denotes mouse
T8273 1826-1827 NN denotes B
T8274 1828-1835 NN denotes lineage
T8275 1836-1841 NN denotes cells
T8276 1842-1843 -LRB- denotes [
T8277 1843-1845 CD denotes 26
T8278 1845-1846 -RRB- denotes ]
T8279 1848-1860 RB denotes Additionally
T8280 1860-1861 -COMMA- denotes ,
T8281 1862-1867 NN denotes BMP-4
T8282 1868-1876 VB denotes inhibits
T8283 1877-1886 NN denotes thymocyte
T8284 1887-1900 NN denotes proliferation
T8285 1901-1902 -LRB- denotes [
T8286 1902-1903 CD denotes 6
T8287 1903-1904 -RRB- denotes ]
T8288 1906-1911 VB denotes Taken
T8289 1912-1920 RB denotes together
T8290 1920-1921 -COMMA- denotes ,
T8291 1922-1927 DT denotes these
T8292 1928-1932 NN denotes data
T8293 1933-1940 VB denotes suggest
T8294 1941-1945 IN denotes that
T8295 1946-1949 DT denotes the
T8296 1950-1954 NN denotes role
T8297 1955-1957 IN denotes of
T8298 1958-1962 NN denotes BMPs
T8299 1963-1965 IN denotes in
T8300 1966-1969 DT denotes the
T8301 1970-1980 NN denotes regulation
T8302 1981-1983 IN denotes of
T8303 1984-1997 NN denotes proliferation
T8304 1998-2001 CC denotes and
T8305 2002-2011 NN denotes apoptosis
T8306 2012-2014 VB denotes is
T8307 2015-2021 RB denotes highly
T8308 2022-2026 NN denotes cell
T8309 2027-2031 NN denotes type
T8310 2032-2041 JJ denotes dependent
T8311 2043-2045 TO denotes To
T8312 2046-2053 VB denotes examine
T8313 2054-2057 WRB denotes how
T8314 2058-2063 NN denotes BMP-6
T8315 2064-2070 VB denotes exerts
T8316 2071-2074 PRP-DOLLAR- denotes its
T8317 2075-2085 JJ denotes functional
T8318 2086-2093 NN denotes effects
T8319 2094-2096 IN denotes in
T8320 2097-2098 NN denotes B
T8321 2099-2104 NN denotes cells
T8322 2104-2105 -COMMA- denotes ,
T8323 2106-2108 PRP denotes we
T8324 2109-2117 VB denotes analysed
T8325 2118-2121 NN denotes BMP
T8326 2122-2130 NN denotes receptor
T8327 2131-2141 NN denotes expression
T8328 2142-2144 IN denotes by
T8329 2145-2152 JJ denotes western
T8330 2153-2157 NN denotes blot
T8331 2158-2166 NN denotes analysis
T8332 2168-2173 JJ denotes Human
T8333 2174-2184 JJ denotes peripheral
T8334 2185-2186 NN denotes B
T8335 2187-2192 NN denotes cells
T8336 2193-2197 VB denotes were
T8337 2198-2203 VB denotes found
T8338 2204-2206 TO denotes to
T8339 2207-2214 VB denotes express
T8340 2215-2218 DT denotes the
T8341 2219-2222 NN denotes BMP
T8342 2223-2227 NN denotes type
T8343 2228-2229 CD denotes I
T8344 2230-2239 NN denotes receptors
T8345 2240-2247 NN denotes Act-RIA
T8346 2248-2251 CC denotes and
T8347 2252-2259 NN denotes BMP-RIB
T8348 2259-2260 -COMMA- denotes ,
T8349 2261-2264 CC denotes and
T8350 2265-2268 DT denotes the
T8351 2269-2273 NN denotes type
T8352 2274-2286 NN denotes II-receptors
T8353 2287-2294 NN denotes BMP-RII
T8354 2295-2298 CC denotes and
T8355 2299-2307 NN denotes Act-RIIb
T8356 2307-2308 -COMMA- denotes ,
T8357 2309-2314 WDT denotes which
T8358 2315-2321 VB denotes signal
T8359 2322-2327 IN denotes after
T8360 2328-2335 NN denotes binding
T8361 2336-2338 IN denotes of
T8362 2339-2346 JJ denotes several
T8363 2347-2351 NN denotes BMPs
T8364 2351-2352 -COMMA- denotes ,
T8365 2353-2362 VB denotes including
T8366 2363-2368 NN denotes BMP-6
T8367 2369-2370 -LRB- denotes [
T8368 2370-2375 CD denotes 16,13
T8369 2375-2376 -RRB- denotes ]
T8370 2378-2380 TO denotes To
T8371 2381-2388 RB denotes further
T8372 2389-2396 VB denotes explore
T8373 2397-2402 NN denotes BMP-6
T8374 2403-2410 VB denotes induced
T8375 2411-2421 NN denotes signalling
T8376 2421-2422 -COMMA- denotes ,
T8377 2423-2433 NN denotes activation
T8378 2434-2436 IN denotes of
T8379 2437-2444 JJ denotes several
T8380 2445-2453 NN denotes pathways
T8381 2454-2456 VB denotes is
T8382 2457-2465 JJ denotes possible
T8383 2467-2470 DT denotes The
T8384 2471-2476 JJ denotes major
T8385 2477-2487 NN denotes signalling
T8386 2488-2495 NN denotes pathway
T8387 2496-2501 VB denotes known
T8388 2502-2504 TO denotes to
T8389 2505-2509 NN denotes date
T8390 2509-2510 -COMMA- denotes ,
T8391 2511-2513 VB denotes is
T8392 2514-2524 NN denotes activation
T8393 2525-2527 IN denotes of
T8394 2528-2535 NN denotes R-Smads
T8395 2536-2537 -LRB- denotes [
T8396 2537-2542 CD denotes 13,27
T8397 2542-2543 -RRB- denotes ]
T8398 2545-2547 IN denotes In
T8399 2548-2552 DT denotes that
T8400 2553-2560 NN denotes respect
T8401 2560-2561 -COMMA- denotes ,
T8402 2562-2566 NN denotes BMPs
T8403 2567-2571 VB denotes have
T8404 2572-2576 VB denotes been
T8405 2577-2582 VB denotes shown
T8406 2583-2585 TO denotes to
T8407 2586-2591 VB denotes exert
T8408 2592-2609 JJ denotes antiproliferative
T8409 2610-2617 NN denotes effects
T8410 2618-2620 IN denotes in
T8411 2621-2622 NN denotes B
T8412 2623-2630 NN denotes lineage
T8413 2631-2636 NN denotes cells
T8414 2637-2640 IN denotes via
T8415 2641-2656 NN denotes phosphorylation
T8416 2657-2659 IN denotes of
T8417 2660-2666 NN denotes R-Smad
T8418 2667-2668 -LRB- denotes [
T8419 2668-2673 CD denotes 11,28
T8420 2673-2674 -RRB- denotes ]
T8421 2676-2687 RB denotes Furthermore
T8422 2687-2688 -COMMA- denotes ,
T8423 2689-2694 NN denotes BMP-2
T8424 2695-2698 VB denotes has
T8425 2699-2703 VB denotes been
T8426 2704-2709 VB denotes shown
T8427 2710-2712 TO denotes to
T8428 2713-2719 VB denotes induce
T8429 2720-2730 NN denotes activation
T8430 2731-2733 IN denotes of
T8431 2734-2739 NN denotes STAT3
T8432 2740-2742 IN denotes in
T8433 2743-2750 NN denotes myeloma
T8434 2751-2756 NN denotes cells
T8435 2757-2758 -LRB- denotes [
T8436 2758-2759 CD denotes 9
T8437 2759-2760 -RRB- denotes ]
T8438 2762-2769 RB denotes However
T8439 2769-2770 -COMMA- denotes ,
T8440 2771-2786 NN denotes phosphorylation
T8441 2787-2789 IN denotes of
T8442 2790-2796 NN denotes R-Smad
T8443 2797-2800 VB denotes was
T8444 2801-2804 RB denotes not
T8445 2805-2817 VB denotes investigated
T8446 2818-2820 IN denotes in
T8447 2821-2825 DT denotes that
T8448 2826-2831 NN denotes study
T8449 2833-2838 NN denotes BMP-2
T8450 2839-2842 VB denotes has
T8451 2843-2847 RB denotes also
T8452 2848-2852 VB denotes been
T8453 2853-2858 VB denotes shown
T8454 2859-2861 TO denotes to
T8455 2862-2868 VB denotes induce
T8456 2869-2884 NN denotes phosphorylation
T8457 2885-2887 IN denotes of
T8458 2888-2891 NN denotes p38
T8459 2892-2893 -LRB- denotes [
T8460 2893-2895 CD denotes 29
T8461 2895-2896 -RRB- denotes ]
T8462 2898-2902 RB denotes Thus
T8463 2902-2903 -COMMA- denotes ,
T8464 2904-2919 NN denotes phosphorylation
T8465 2920-2922 IN denotes of
T8466 2923-2926 NN denotes p38
T8467 2926-2927 -COMMA- denotes ,
T8468 2928-2933 NN denotes STAT3
T8469 2934-2937 CC denotes and
T8470 2938-2947 NN denotes Smad1/5/8
T8471 2948-2957 VB denotes represent
T8472 2958-2967 JJ denotes important
T8473 2968-2982 JJ denotes BMP-signalling
T8474 2983-2991 NN denotes pathways
T8475 2992-2996 WDT denotes that
T8476 2997-3005 VB denotes mediated
T8477 3006-3009 DT denotes the
T8478 3010-3017 NN denotes effects
T8479 3018-3020 IN denotes of
T8480 3021-3025 NN denotes BMPs
T8481 3026-3029 CC denotes and
T8482 3030-3034 RB denotes even
T8483 3035-3045 JJ denotes cross-talk
T8484 3046-3053 IN denotes between
T8485 3054-3059 DT denotes these
T8486 3060-3068 NN denotes pathways
T8487 3069-3072 VB denotes has
T8488 3073-3077 VB denotes been
T8489 3078-3086 VB denotes reported
T8490 3087-3088 -LRB- denotes [
T8491 3088-3093 CD denotes 29,30
T8492 3093-3094 -RRB- denotes ]
T8493 3096-3098 IN denotes In
T8494 3099-3102 DT denotes the
T8495 3103-3110 JJ denotes present
T8496 3111-3116 NN denotes study
T8497 3116-3117 -COMMA- denotes ,
T8498 3118-3120 PRP denotes we
T8499 3121-3125 VB denotes were
T8500 3126-3129 RB denotes not
T8501 3130-3134 JJ denotes able
T8502 3135-3137 TO denotes to
T8503 3138-3144 VB denotes detect
T8504 3145-3158 JJ denotes BMP-6-induced
T8505 3159-3166 NN denotes changes
T8506 3167-3169 IN denotes in
T8507 3170-3173 DT denotes the
T8508 3174-3189 NN denotes phosphorylation
T8509 3190-3196 NN denotes status
T8510 3197-3199 IN denotes of
T8511 3200-3205 NN denotes STAT3
T8512 3206-3208 CC denotes or
T8513 3209-3212 NN denotes p38
T8514 3213-3215 IN denotes in
T8515 3216-3221 JJ denotes human
T8516 3222-3232 JJ denotes peripheral
T8517 3233-3234 NN denotes B
T8518 3235-3240 NN denotes cells
T8519 3242-3249 RB denotes Instead
T8520 3249-3250 -COMMA- denotes ,
T8521 3251-3252 DT denotes a
T8522 3253-3258 JJ denotes rapid
T8523 3259-3262 CC denotes and
T8524 3263-3269 JJ denotes marked
T8525 3270-3285 NN denotes phosphorylation
T8526 3286-3288 IN denotes of
T8527 3289-3298 NN denotes Smad1/5/8
T8528 3299-3302 VB denotes was
T8529 3303-3311 VB denotes revealed
T8530 3313-3315 IN denotes In
T8531 3316-3317 DT denotes a
T8532 3318-3326 JJ denotes parallel
T8533 3327-3332 NN denotes study
T8534 3332-3333 -COMMA- denotes ,
T8535 3334-3336 PRP denotes we
T8536 3337-3341 VB denotes have
T8537 3342-3347 VB denotes found
T8538 3348-3352 IN denotes that
T8539 3353-3358 JJ denotes other
T8540 3359-3363 NN denotes BMPs
T8541 3364-3368 RB denotes also
T8542 3369-3376 VB denotes induced
T8543 3377-3392 NN denotes phosphorylation
T8544 3393-3395 IN denotes of
T8545 3396-3405 NN denotes Smad1/5/8
T8546 3406-3408 IN denotes in
T8547 3409-3419 JJ denotes peripheral
T8548 3420-3421 NN denotes B
T8549 3422-3427 NN denotes cells
T8550 3428-3429 -LRB- denotes (
T8551 3429-3433 NN denotes data
T8552 3434-3437 RB denotes not
T8553 3438-3443 VB denotes shown
T8554 3443-3444 -RRB- denotes )
T8555 3446-3448 PRP denotes We
T8556 3449-3452 VB denotes are
T8557 3453-3462 RB denotes currently
T8558 3463-3471 VB denotes pursuing
T8559 3472-3482 NN denotes microarray
T8560 3483-3490 NN denotes studies
T8561 3491-3493 TO denotes to
T8562 3494-3502 VB denotes identify
T8563 3503-3506 DT denotes the
T8564 3507-3517 NN denotes signalling
T8565 3518-3526 NN denotes pathways
T8566 3527-3530 CC denotes and
T8567 3531-3537 NN denotes target
T8568 3538-3543 NN denotes genes
T8569 3544-3548 WDT denotes that
T8570 3549-3552 VB denotes are
T8571 3553-3564 RB denotes differently
T8572 3565-3574 VB denotes regulated
T8573 3575-3577 IN denotes by
T8574 3578-3581 DT denotes the
T8575 3582-3589 JJ denotes various
T8576 3590-3594 NN denotes BMPs
T8577 3595-3597 IN denotes in
T8578 3598-3603 JJ denotes human
T8579 3604-3605 NN denotes B
T8580 3606-3611 NN denotes cells
T8581 3613-3625 NN denotes Upregulation
T8582 3626-3628 IN denotes of
T8583 3629-3632 NN denotes Id1
T8584 3633-3636 IN denotes via
T8585 3637-3646 NN denotes Smad1/5/8
T8586 3647-3662 NN denotes phosphorylation
T8587 3663-3665 VB denotes is
T8588 3666-3667 DT denotes a
T8589 3668-3673 JJ denotes known
T8590 3674-3683 NN denotes mechanism
T8591 3684-3687 IN denotes for
T8592 3688-3693 NN denotes BMP-6
T8593 3694-3704 NN denotes signalling
T8594 3705-3707 IN denotes in
T8595 3708-3713 JJ denotes other
T8596 3714-3718 NN denotes cell
T8597 3719-3726 NN denotes systems
T8598 3727-3728 -LRB- denotes [
T8599 3728-3733 CD denotes 31,32
T8600 3733-3734 -RRB- denotes ]
T8601 3735-3738 CC denotes and
T8602 3739-3749 NN denotes regulation
T8603 3750-3752 IN denotes of
T8604 3753-3764 NN denotes Id-proteins
T8605 3765-3767 VB denotes is
T8606 3768-3775 VB denotes thought
T8607 3776-3778 TO denotes to
T8608 3779-3781 VB denotes be
T8609 3782-3784 DT denotes an
T8610 3785-3794 JJ denotes important
T8611 3795-3804 NN denotes mechanism
T8612 3805-3808 IN denotes for
T8613 3809-3824 NN denotes Smad-signalling
T8614 3825-3826 -LRB- denotes [
T8615 3826-3828 CD denotes 17
T8616 3828-3829 -RRB- denotes ]
T8617 3831-3833 IN denotes In
T8618 3834-3837 DT denotes the
T8619 3838-3845 JJ denotes present
T8620 3846-3851 NN denotes study
T8621 3851-3852 -COMMA- denotes ,
T8622 3853-3862 JJ denotes real-time
T8623 3863-3869 NN denotes RT-PCR
T8624 3870-3881 NN denotes experiments
T8625 3882-3890 VB denotes revealed
T8626 3891-3892 DT denotes a
T8627 3893-3901 JJ denotes specific
T8628 3902-3911 JJ denotes four-fold
T8629 3912-3924 NN denotes upregulation
T8630 3925-3928 IN denotes for
T8631 3929-3932 NN denotes Id1
T8632 3933-3935 IN denotes in
T8633 3936-3949 JJ denotes BMP-6-treated
T8634 3950-3951 NN denotes B
T8635 3952-3957 NN denotes cells
T8636 3957-3958 -COMMA- denotes ,
T8637 3959-3964 IN denotes while
T8638 3965-3968 DT denotes the
T8639 3969-3975 NN denotes amount
T8640 3976-3978 IN denotes of
T8641 3979-3986 NN denotes Id2–Id4
T8642 3987-3995 VB denotes remained
T8643 3996-4005 JJ denotes unchanged
T8644 4007-4009 IN denotes In
T8645 4010-4019 NN denotes agreement
T8646 4020-4024 IN denotes with
T8647 4025-4029 DT denotes this
T8648 4029-4030 -COMMA- denotes ,
T8649 4031-4038 JJ denotes western
T8650 4039-4043 NN denotes blot
T8651 4044-4052 NN denotes analysis
T8652 4053-4065 VB denotes demonstrated
T8653 4066-4068 DT denotes an
T8654 4069-4081 NN denotes upregulation
T8655 4082-4084 IN denotes of
T8656 4085-4088 NN denotes Id1
T8657 4089-4096 NN denotes protein
T8658 4096-4097 -COMMA- denotes ,
T8659 4098-4103 IN denotes while
T8660 4104-4107 DT denotes the
T8661 4108-4114 NN denotes amount
T8662 4115-4117 IN denotes of
T8663 4118-4121 NN denotes Id2
T8664 4122-4125 CC denotes and
T8665 4126-4129 NN denotes Id3
T8666 4130-4137 NN denotes protein
T8667 4138-4144 NN denotes levels
T8668 4145-4153 VB denotes remained
T8669 4154-4163 JJ denotes unchanged
T8670 4165-4175 RB denotes Previously
T8671 4175-4176 -COMMA- denotes ,
T8672 4177-4180 NN denotes Id1
T8673 4181-4184 VB denotes has
T8674 4185-4189 VB denotes been
T8675 4190-4200 VB denotes considered
T8676 4201-4204 RB denotes not
T8677 4205-4207 TO denotes to
T8678 4208-4210 VB denotes be
T8679 4211-4220 VB denotes expressed
T8680 4221-4223 IN denotes in
T8681 4224-4229 JJ denotes later
T8682 4230-4243 JJ denotes developmental
T8683 4244-4250 NN denotes stages
T8684 4251-4255 IN denotes than
T8685 4256-4261 JJ denotes pro-B
T8686 4262-4267 NN denotes cells
T8687 4268-4269 -LRB- denotes [
T8688 4269-4274 CD denotes 33,34
T8689 4274-4275 -RRB- denotes ]
T8690 4275-4276 -COMMA- denotes ,
T8691 4277-4280 CC denotes and
T8692 4281-4284 PRP-DOLLAR- denotes its
T8693 4285-4297 JJ denotes constitutive
T8694 4298-4308 NN denotes expression
T8695 4309-4312 VB denotes has
T8696 4313-4317 VB denotes been
T8697 4318-4326 VB denotes reported
T8698 4327-4329 TO denotes to
T8699 4330-4336 VB denotes impair
T8700 4337-4342 NN denotes mouse
T8701 4343-4344 NN denotes B
T8702 4345-4349 NN denotes cell
T8703 4350-4361 NN denotes development
T8704 4362-4363 -LRB- denotes [
T8705 4363-4365 CD denotes 35
T8706 4365-4366 -RRB- denotes ]
T8707 4368-4377 RB denotes Therefore
T8708 4377-4378 -COMMA- denotes ,
T8709 4379-4382 PRP-DOLLAR- denotes our
T8710 4383-4396 NN denotes demonstration
T8711 4397-4399 IN denotes of
T8712 4400-4403 DT denotes the
T8713 4404-4418 JJ denotes time-dependent
T8714 4419-4431 NN denotes upregulation
T8715 4432-4434 IN denotes of
T8716 4435-4438 NN denotes Id1
T8717 4439-4443 NN denotes mRNA
T8718 4444-4447 CC denotes and
T8719 4448-4455 NN denotes protein
T8720 4456-4458 IN denotes in
T8721 4459-4465 JJ denotes mature
T8722 4466-4472 JJ denotes normal
T8723 4473-4478 JJ denotes human
T8724 4479-4480 NN denotes B
T8725 4481-4486 NN denotes cells
T8726 4487-4489 VB denotes is
T8727 4490-4492 IN denotes of
T8728 4493-4503 JJ denotes particular
T8729 4504-4512 NN denotes interest
T8730 4514-4516 IN denotes In
T8731 4517-4521 DT denotes that
T8732 4522-4529 NN denotes respect
T8733 4529-4530 -COMMA- denotes ,
T8734 4531-4533 PRP denotes it
T8735 4534-4536 VB denotes is
T8736 4537-4547 JJ denotes noteworthy
T8737 4548-4552 IN denotes that
T8738 4553-4558 NN denotes TGF-β
T8739 4559-4569 NN denotes signalling
T8740 4570-4572 IN denotes in
T8741 4573-4578 JJ denotes early
T8742 4579-4582 CC denotes and
T8743 4583-4589 JJ denotes mature
T8744 4590-4591 NN denotes B
T8745 4592-4597 NN denotes cells
T8746 4598-4605 VB denotes induces
T8747 4606-4610 CC denotes both
T8748 4611-4614 NN denotes Id2
T8749 4615-4618 CC denotes and
T8750 4619-4622 NN denotes Id3
T8751 4623-4633 NN denotes expression
T8752 4634-4635 -LRB- denotes [
T8753 4635-4640 CD denotes 36,37
T8754 4640-4641 -RRB- denotes ]
T8755 4641-4642 -COMMA- denotes ,
T8756 4643-4646 CC denotes but
T8757 4647-4650 RB denotes not
T8758 4651-4654 NN denotes Id1
T8759 4655-4656 -LRB- denotes (
T8760 4656-4660 NN denotes data
T8761 4661-4664 RB denotes not
T8762 4665-4670 VB denotes shown
T8763 4670-4671 -RRB- denotes )
T8764 4673-4686 RB denotes Interestingly
T8765 4686-4687 -COMMA- denotes ,
T8766 4688-4693 DT denotes these
T8767 4694-4701 NN denotes results
T8768 4702-4706 VB denotes show
T8769 4707-4711 IN denotes that
T8770 4712-4719 JJ denotes various
T8771 4720-4727 NN denotes members
T8772 4728-4730 IN denotes of
T8773 4731-4734 DT denotes the
T8774 4735-4740 NN denotes TGF-β
T8775 4741-4747 NN denotes family
T8776 4748-4756 VB denotes regulate
T8777 4757-4759 NN denotes Id
T8778 4760-4768 NN denotes proteins
T8779 4769-4780 RB denotes differently
T8780 4782-4785 NN denotes Id2
T8781 4786-4789 CC denotes and
T8782 4790-4793 NN denotes Id3
T8783 4794-4797 VB denotes are
T8784 4798-4808 VB denotes considered
T8785 4809-4811 TO denotes to
T8786 4812-4814 VB denotes be
T8787 4815-4818 DT denotes the
T8788 4819-4821 NN denotes Id
T8789 4822-4830 NN denotes proteins
T8790 4831-4837 RB denotes mainly
T8791 4838-4847 VB denotes expressed
T8792 4848-4850 IN denotes in
T8793 4851-4857 JJ denotes mature
T8794 4858-4859 NN denotes B
T8795 4860-4865 NN denotes cells
T8796 4866-4867 -LRB- denotes [
T8797 4867-4869 CD denotes 38
T8798 4869-4870 -RRB- denotes ]
T8799 4872-4875 DT denotes The
T8800 4876-4883 JJ denotes present
T8801 4884-4889 NN denotes study
T8802 4890-4894 RB denotes also
T8803 4895-4900 VB denotes found
T8804 4901-4904 NN denotes Id2
T8805 4905-4908 CC denotes and
T8806 4909-4912 NN denotes Id3
T8807 4913-4920 NN denotes protein
T8808 4921-4923 IN denotes in
T8809 4924-4925 NN denotes B
T8810 4926-4931 NN denotes cells
T8811 4932-4934 TO denotes to
T8812 4935-4937 VB denotes be
T8813 4938-4942 RB denotes more
T8814 4943-4949 RB denotes highly
T8815 4950-4959 VB denotes expressed
T8816 4960-4964 IN denotes than
T8817 4965-4968 NN denotes Id1
T8818 4969-4971 IN denotes in
T8819 4972-4979 VB denotes resting
T8820 4980-4981 NN denotes B
T8821 4982-4987 NN denotes cells
T8822 4989-4996 RB denotes However
T8823 4996-4997 -COMMA- denotes ,
T8824 4998-5003 NN denotes BMP-6
T8825 5004-5007 VB denotes did
T8826 5008-5011 RB denotes not
T8827 5012-5018 VB denotes induce
T8828 5019-5030 JJ denotes significant
T8829 5031-5038 NN denotes changes
T8830 5039-5041 IN denotes in
T8831 5042-5045 DT denotes the
T8832 5046-5053 NN denotes protein
T8833 5054-5064 NN denotes expression
T8834 5065-5067 IN denotes of
T8835 5068-5071 NN denotes Id2
T8836 5072-5075 CC denotes and
T8837 5076-5079 NN denotes Id3
T8838 5081-5083 PRP denotes It
T8839 5084-5086 VB denotes is
T8840 5087-5095 VB denotes believed
T8841 5096-5100 IN denotes that
T8842 5101-5103 NN denotes Id
T8843 5104-5112 NN denotes proteins
T8844 5113-5118 VB denotes block
T8845 5119-5134 NN denotes differentiation
T8846 5135-5138 CC denotes and
T8847 5139-5146 VB denotes promote
T8848 5147-5160 NN denotes proliferation
T8849 5161-5163 IN denotes in
T8850 5164-5171 JJ denotes various
T8851 5172-5176 NN denotes cell
T8852 5177-5182 NN denotes types
T8853 5183-5184 -LRB- denotes [
T8854 5184-5189 CD denotes 39,33
T8855 5189-5190 -RRB- denotes ]
T8856 5192-5194 NN denotes Id
T8857 5195-5203 NN denotes proteins
T8858 5204-5207 VB denotes act
T8859 5208-5210 IN denotes as
T8860 5211-5228 JJ denotes dominant-negative
T8861 5229-5239 NN denotes inhibitors
T8862 5240-5242 IN denotes of
T8863 5243-5253 NN denotes E-proteins
T8864 5254-5257 CC denotes and
T8865 5258-5262 NN denotes Pax5
T8866 5263-5271 NN denotes function
T8867 5272-5274 IN denotes by
T8868 5275-5282 VB denotes forming
T8869 5283-5289 NN denotes dimers
T8870 5290-5294 IN denotes with
T8871 5295-5300 DT denotes these
T8872 5301-5309 NN denotes proteins
T8873 5309-5310 -COMMA- denotes ,
T8874 5311-5317 VB denotes making
T8875 5318-5322 PRP denotes them
T8876 5323-5329 JJ denotes unable
T8877 5330-5332 TO denotes to
T8878 5333-5337 VB denotes bind
T8879 5338-5341 NN denotes DNA
T8880 5343-5345 PRP denotes It
T8881 5346-5349 VB denotes has
T8882 5350-5354 VB denotes been
T8883 5355-5363 VB denotes proposed
T8884 5364-5368 IN denotes that
T8885 5369-5372 DT denotes the
T8886 5373-5380 NN denotes balance
T8887 5381-5386 IN denotes among
T8888 5387-5397 NN denotes E-proteins
T8889 5397-5398 -COMMA- denotes ,
T8890 5399-5403 NN denotes Pax5
T8891 5404-5407 CC denotes and
T8892 5408-5410 NN denotes Id
T8893 5411-5419 NN denotes proteins
T8894 5420-5425 MD denotes might
T8895 5426-5430 VB denotes have
T8896 5431-5433 DT denotes an
T8897 5434-5443 JJ denotes important
T8898 5444-5448 NN denotes role
T8899 5449-5451 IN denotes in
T8900 5452-5461 VB denotes activated
T8901 5462-5463 NN denotes B
T8902 5464-5469 NN denotes cells
T8903 5470-5471 -LRB- denotes [
T8904 5471-5473 CD denotes 38
T8905 5473-5474 -RRB- denotes ]
T8906 5476-5478 IN denotes In
T8907 5479-5483 DT denotes that
T8908 5484-5491 NN denotes respect
T8909 5491-5492 -COMMA- denotes ,
T8910 5493-5503 NN denotes E-proteins
T8911 5504-5508 VB denotes have
T8912 5509-5513 VB denotes been
T8913 5514-5524 VB denotes implicated
T8914 5525-5527 IN denotes in
T8915 5528-5532 CC denotes both
T8916 5533-5536 DT denotes the
T8917 5537-5546 NN denotes promotion
T8918 5547-5550 CC denotes and
T8919 5551-5561 NN denotes inhibition
T8920 5562-5564 IN denotes of
T8921 5565-5569 NN denotes cell
T8922 5570-5578 NN denotes survival
T8923 5579-5582 CC denotes and
T8924 5583-5589 NN denotes growth
T8925 5590-5592 IN denotes at
T8926 5593-5602 JJ denotes different
T8927 5603-5609 NN denotes points
T8928 5610-5612 IN denotes in
T8929 5613-5623 NN denotes lymphocyte
T8930 5624-5635 NN denotes development
T8931 5636-5637 -LRB- denotes [
T8932 5637-5639 CD denotes 40
T8933 5639-5640 -RRB- denotes ]
T8934 5642-5645 DT denotes The
T8935 5646-5663 JJ denotes antiproliferative
T8936 5664-5667 CC denotes and
T8937 5668-5673 NN denotes death
T8938 5674-5682 VB denotes inducing
T8939 5683-5689 NN denotes effect
T8940 5690-5692 IN denotes of
T8941 5693-5698 NN denotes BMP-6
T8942 5699-5701 IN denotes in
T8943 5702-5703 NN denotes B
T8944 5704-5709 NN denotes cells
T8945 5710-5714 IN denotes with
T8946 5715-5726 JJ denotes concomitant
T8947 5727-5739 NN denotes upregulation
T8948 5740-5742 IN denotes of
T8949 5743-5746 NN denotes Id1
T8950 5747-5754 NN denotes protein
T8951 5755-5757 VB denotes is
T8952 5758-5767 RB denotes therefore
T8953 5768-5770 IN denotes in
T8954 5771-5775 NN denotes line
T8955 5776-5780 IN denotes with
T8956 5781-5784 DT denotes the
T8957 5785-5789 NN denotes view
T8958 5790-5794 IN denotes that
T8959 5795-5797 NN denotes Id
T8960 5798-5806 NN denotes proteins
T8961 5807-5810 VB denotes are
T8962 5811-5819 VB denotes required
T8963 5820-5823 IN denotes for
T8964 5824-5827 DT denotes the
T8965 5828-5837 NN denotes induction
T8966 5838-5840 IN denotes of
T8967 5841-5847 NN denotes growth
T8968 5848-5854 NN denotes arrest
T8969 5855-5858 CC denotes and
T8970 5859-5868 NN denotes apoptosis
T8971 5869-5871 IN denotes in
T8972 5872-5884 NN denotes B-lymphocyte
T8973 5885-5896 NN denotes progenitors
T8974 5897-5899 IN denotes by
T8975 5900-5905 NN denotes TGF-β
T8976 5906-5907 -LRB- denotes [
T8977 5907-5909 CD denotes 40
T8978 5909-5910 -RRB- denotes ]
T8979 5912-5923 RB denotes Furthermore
T8980 5923-5924 -COMMA- denotes ,
T8981 5925-5927 NN denotes Id
T8982 5928-5936 NN denotes proteins
T8983 5937-5940 VB denotes are
T8984 5941-5946 VB denotes known
T8985 5947-5949 IN denotes as
T8986 5950-5959 JJ denotes important
T8987 5960-5965 NN denotes parts
T8988 5966-5968 IN denotes of
T8989 5969-5979 NN denotes signalling
T8990 5980-5988 NN denotes pathways
T8991 5989-5997 VB denotes involved
T8992 5998-6000 IN denotes in
T8993 6001-6012 NN denotes development
T8994 6012-6013 -COMMA- denotes ,
T8995 6014-6018 NN denotes cell
T8996 6019-6024 NN denotes cycle
T8997 6025-6028 CC denotes and
T8998 6029-6042 NN denotes tumorigenesis
T8999 6043-6044 -LRB- denotes [
T9000 6044-6046 CD denotes 32
T9001 6046-6047 -RRB- denotes ]
T9002 6049-6051 PRP denotes It
T9003 6052-6054 VB denotes is
T9004 6055-6059 RB denotes well
T9005 6060-6071 VB denotes established
T9006 6072-6076 IN denotes that
T9007 6077-6084 JJ denotes various
T9008 6085-6092 NN denotes members
T9009 6093-6095 IN denotes of
T9010 6096-6099 DT denotes the
T9011 6100-6102 NN denotes Id
T9012 6103-6109 NN denotes family
T9013 6110-6113 VB denotes are
T9014 6114-6127 VB denotes overexpressed
T9015 6128-6130 IN denotes in
T9016 6131-6132 DT denotes a
T9017 6133-6138 NN denotes range
T9018 6139-6141 IN denotes of
T9019 6142-6147 JJ denotes human
T9020 6148-6155 NN denotes tumours
T9021 6156-6159 CC denotes and
T9022 6160-6169 RB denotes generally
T9023 6169-6170 -COMMA- denotes ,
T9024 6171-6174 NN denotes Id1
T9025 6175-6182 VB denotes appears
T9026 6183-6185 TO denotes to
T9027 6186-6188 VB denotes be
T9028 6189-6192 DT denotes the
T9029 6193-6199 NN denotes family
T9030 6200-6206 NN denotes member
T9031 6207-6211 RB denotes most
T9032 6212-6218 RB denotes widely
T9033 6219-6232 VB denotes overexpressed
T9034 6233-6235 IN denotes in
T9035 6236-6237 DT denotes a
T9036 6238-6245 NN denotes variety
T9037 6246-6248 IN denotes of
T9038 6249-6254 JJ denotes human
T9039 6255-6267 NN denotes malignancies
T9040 6268-6269 -LRB- denotes [
T9041 6269-6271 CD denotes 41
T9042 6271-6272 -RRB- denotes ]
T9043 6272-6273 -COMMA- denotes ,
T9044 6274-6283 VB denotes including
T9045 6284-6292 JJ denotes multiple
T9046 6293-6300 NN denotes myeloma
T9047 6301-6302 -LRB- denotes [
T9048 6302-6307 CD denotes 42,32
T9049 6307-6308 -RRB- denotes ]
T9050 6310-6322 RB denotes Additionally
T9051 6322-6323 -COMMA- denotes ,
T9052 6324-6327 PRP-DOLLAR- denotes our
T9053 6328-6336 NN denotes findings
T9054 6337-6341 IN denotes that
T9055 6342-6347 NN denotes BMP-6
T9056 6348-6357 VB denotes activates
T9057 6358-6371 JJ denotes intracellular
T9058 6372-6382 NN denotes signalling
T9059 6383-6391 NN denotes pathways
T9060 6392-6394 IN denotes in
T9061 6395-6400 JJ denotes human
T9062 6401-6402 NN denotes B
T9063 6403-6408 NN denotes cells
T9064 6409-6414 MD denotes might
T9065 6415-6417 VB denotes be
T9066 6418-6420 IN denotes of
T9067 6421-6430 JJ denotes potential
T9068 6431-6449 JJ denotes pathophysiological
T9069 6450-6462 NN denotes significance
T9070 6463-6465 IN denotes in
T9071 6466-6474 NN denotes lymphoma
T9072 6475-6478 CC denotes and
T9073 6479-6491 NN denotes inflammation
T9074 6493-6497 JJ denotes High
T9075 6498-6503 NN denotes BMP-6
T9076 6504-6508 NN denotes mRNA
T9077 6509-6519 NN denotes expression
T9078 6520-6522 IN denotes in
T9079 6523-6528 NN denotes DLBCL
T9080 6529-6532 VB denotes has
T9081 6533-6537 VB denotes been
T9082 6538-6543 VB denotes shown
T9083 6544-6546 TO denotes to
T9084 6547-6556 VB denotes correlate
T9085 6557-6559 TO denotes to
T9086 6560-6572 JJ denotes unfavourable
T9087 6573-6580 NN denotes outcome
T9088 6581-6582 -LRB- denotes [
T9089 6582-6584 CD denotes 12
T9090 6584-6585 -RRB- denotes ]
T9091 6587-6589 IN denotes In
T9092 6590-6594 DT denotes this
T9093 6595-6602 NN denotes respect
T9094 6602-6603 -COMMA- denotes ,
T9095 6604-6606 PRP denotes it
T9096 6607-6609 VB denotes is
T9097 6610-6612 IN denotes of
T9098 6613-6621 NN denotes interest
T9099 6622-6626 WDT denotes that
T9100 6627-6635 VB denotes targeted
T9101 6636-6646 NN denotes expression
T9102 6647-6649 IN denotes of
T9103 6650-6653 NN denotes Id1
T9104 6654-6656 TO denotes to
T9105 6657-6670 NN denotes B-lymphocytes
T9106 6671-6679 VB denotes resulted
T9107 6680-6682 IN denotes in
T9108 6683-6691 JJ denotes aberrant
T9109 6692-6693 NN denotes B
T9110 6694-6698 NN denotes cell
T9111 6699-6710 NN denotes development
T9112 6710-6711 -COMMA- denotes ,
T9113 6712-6719 JJ denotes massive
T9114 6720-6729 NN denotes apoptosis
T9115 6729-6730 -COMMA- denotes ,
T9116 6731-6734 CC denotes and
T9117 6735-6745 JJ denotes subsequent
T9118 6746-6757 NN denotes development
T9119 6758-6760 IN denotes of
T9120 6761-6762 NN denotes B
T9121 6763-6767 NN denotes cell
T9122 6768-6777 NN denotes lymphomas
T9123 6778-6779 -LRB- denotes [
T9124 6779-6781 CD denotes 35
T9125 6781-6782 -RRB- denotes ]
T9126 6784-6792 RB denotes Moreover
T9127 6792-6793 -COMMA- denotes ,
T9128 6794-6799 NN denotes BMP-6
T9129 6800-6803 VB denotes has
T9130 6804-6808 VB denotes been
T9131 6809-6818 VB denotes suggested
T9132 6819-6821 TO denotes to
T9133 6822-6826 VB denotes play
T9134 6827-6828 DT denotes a
T9135 6829-6833 NN denotes role
T9136 6834-6836 IN denotes in
T9137 6837-6847 JJ denotes rheumatoid
T9138 6848-6857 NN denotes arthritis
T9139 6858-6859 -LRB- denotes (
T9140 6859-6861 NN denotes RA
T9141 6861-6862 -RRB- denotes )
T9142 6863-6864 -LRB- denotes [
T9143 6864-6869 CD denotes 43,44
T9144 6869-6870 -RRB- denotes ]
T9145 6871-6874 CC denotes and
T9146 6875-6883 JJ denotes elevated
T9147 6884-6890 NN denotes levels
T9148 6891-6893 IN denotes of
T9149 6894-6897 NN denotes Id1
T9150 6898-6901 CC denotes and
T9151 6902-6905 NN denotes Id3
T9152 6906-6910 VB denotes have
T9153 6911-6915 VB denotes been
T9154 6916-6921 VB denotes found
T9155 6922-6924 IN denotes in
T9156 6925-6928 DT denotes the
T9157 6929-6936 NN denotes synovia
T9158 6937-6939 IN denotes of
T9159 6940-6951 NN denotes RA-patients
T9160 6952-6953 -LRB- denotes [
T9161 6953-6955 CD denotes 45
T9162 6955-6956 -RRB- denotes ]
T9163 6958-6968 RB denotes Altogether
T9164 6968-6969 -COMMA- denotes ,
T9165 6970-6975 DT denotes these
T9166 6976-6983 NN denotes results
T9167 6984-6989 VB denotes point
T9168 6990-6992 TO denotes to
T9169 6993-6995 DT denotes an
T9170 6996-7005 JJ denotes important
T9171 7006-7010 NN denotes role
T9172 7011-7014 IN denotes for
T9173 7015-7017 NN denotes Id
T9174 7018-7026 NN denotes proteins
T9175 7027-7029 IN denotes in
T9176 7030-7033 DT denotes the
T9177 7034-7044 NN denotes regulation
T9178 7045-7047 IN denotes of
T9179 7048-7054 JJ denotes normal
T9180 7055-7056 NN denotes B
T9181 7057-7061 NN denotes cell
T9182 7062-7073 NN denotes homeostasis
T9183 7074-7077 CC denotes and
T9184 7078-7080 IN denotes in
T9185 7081-7089 NN denotes diseases
T9186 7089-7090 -COMMA- denotes ,
T9187 7091-7096 WRB denotes where
T9188 7097-7098 NN denotes B
T9189 7099-7104 NN denotes cells
T9190 7105-7108 VB denotes are
T9191 7109-7117 VB denotes involved
T9192 7119-7121 PRP denotes It
T9193 7122-7126 MD denotes will
T9194 7127-7136 RB denotes therefore
T9195 7137-7139 VB denotes be
T9196 7140-7149 JJ denotes important
T9197 7150-7152 TO denotes to
T9198 7153-7160 RB denotes further
T9199 7161-7170 VB denotes elucidate
T9200 7171-7174 DT denotes the
T9201 7175-7179 NN denotes role
T9202 7180-7182 IN denotes of
T9203 7183-7187 NN denotes Id-1
T9204 7188-7190 IN denotes in
T9205 7191-7196 JJ denotes human
T9206 7197-7198 NN denotes B
T9207 7199-7204 NN denotes cells
T9208 7205-7207 IN denotes by
T9209 7208-7217 JJ denotes selective
T9210 7218-7222 IN denotes over
T9211 7223-7233 NN denotes expression
T9212 7234-7236 CC denotes or
T9213 7237-7247 NN denotes inhibition
T9214 7248-7250 IN denotes of
T9215 7251-7255 NN denotes Id-1
T9216 7256-7260 NN denotes gene
T9217 7261-7271 NN denotes expression
T9218 7273-7278 VB denotes Given
T9219 7279-7282 DT denotes the
T9220 7283-7287 NN denotes role
T9221 7288-7290 IN denotes of
T9222 7291-7296 NN denotes BMP-6
T9223 7297-7299 IN denotes in
T9224 7300-7306 JJ denotes mature
T9225 7307-7312 JJ denotes human
T9226 7313-7314 NN denotes B
T9227 7315-7320 NN denotes cells
T9228 7321-7333 VB denotes demonstrated
T9229 7334-7338 RB denotes here
T9230 7338-7339 -COMMA- denotes ,
T9231 7340-7354 NN denotes identification
T9232 7355-7357 IN denotes of
T9233 7358-7363 NN denotes BMP-6
T9234 7364-7373 VB denotes producing
T9235 7374-7379 NN denotes cells
T9236 7380-7382 FW denotes in
T9237 7383-7387 FW denotes vivo
T9238 7388-7392 IN denotes with
T9239 7393-7404 NN denotes possibility
T9240 7405-7407 IN denotes of
T9241 7408-7419 NN denotes interaction
T9242 7420-7424 IN denotes with
T9243 7425-7430 NN denotes naïve
T9244 7431-7434 CC denotes and
T9245 7435-7441 NN denotes memory
T9246 7442-7443 NN denotes B
T9247 7444-7449 NN denotes cells
T9248 7450-7455 MD denotes might
T9249 7456-7466 VB denotes contribute
T9250 7467-7469 TO denotes to
T9251 7470-7473 DT denotes the
T9252 7474-7487 NN denotes understanding
T9253 7488-7490 IN denotes of
T9254 7491-7497 JJ denotes mature
T9255 7498-7499 NN denotes B
T9256 7500-7504 NN denotes cell
T9257 7505-7512 NN denotes biology
T9258 7514-7518 JJ denotes High
T9259 7519-7524 NN denotes BMP-6
T9260 7525-7529 NN denotes mRNA
T9261 7530-7540 NN denotes expression
T9262 7541-7543 IN denotes in
T9263 7544-7549 NN denotes DLBCL
T9264 7550-7553 VB denotes has
T9265 7554-7558 VB denotes been
T9266 7559-7567 VB denotes detected
T9267 7568-7570 IN denotes by
T9268 7571-7575 NN denotes gene
T9269 7576-7586 NN denotes expression
T9270 7587-7596 NN denotes profiling
T9271 7597-7598 -LRB- denotes [
T9272 7598-7600 CD denotes 12
T9273 7600-7601 -RRB- denotes ]
T9274 7603-7614 RB denotes Furthermore
T9275 7614-7615 -COMMA- denotes ,
T9276 7616-7626 NN denotes production
T9277 7627-7629 IN denotes of
T9278 7630-7635 NN denotes BMP-6
T9279 7636-7647 NN denotes transcripts
T9280 7648-7650 IN denotes in
T9281 7651-7657 JJ denotes normal
T9282 7658-7667 VB denotes activated
T9283 7668-7669 NN denotes B
T9284 7670-7675 NN denotes cells
T9285 7676-7679 VB denotes was
T9286 7680-7688 VB denotes detected
T9287 7689-7691 IN denotes in
T9288 7692-7695 DT denotes the
T9289 7696-7700 JJ denotes same
T9290 7701-7706 NN denotes study
T9291 7708-7710 IN denotes Of
T9292 7711-7715 NN denotes note
T9293 7715-7716 -COMMA- denotes ,
T9294 7717-7719 DT denotes an
T9295 7720-7729 JJ denotes autocrine
T9296 7730-7735 NN denotes BMP-6
T9297 7736-7740 NN denotes loop
T9298 7741-7744 VB denotes has
T9299 7745-7749 VB denotes been
T9300 7750-7758 VB denotes reported
T9301 7759-7761 IN denotes by
T9302 7762-7768 NN denotes others
T9303 7769-7771 IN denotes in
T9304 7772-7784 NN denotes chondrocytes
T9305 7785-7788 CC denotes and
T9306 7789-7791 IN denotes in
T9307 7792-7795 DT denotes the
T9308 7796-7803 NN denotes ovarium
T9309 7804-7805 -LRB- denotes [
T9310 7805-7813 CD denotes 46,19,18
T9311 7813-7814 -RRB- denotes ]
T9312 7816-7825 RB denotes Therefore
T9313 7825-7826 -COMMA- denotes ,
T9314 7827-7829 PRP denotes we
T9315 7830-7836 VB denotes wanted
T9316 7837-7839 TO denotes to
T9317 7840-7847 VB denotes explore
T9318 7848-7851 DT denotes the
T9319 7852-7863 NN denotes possibility
T9320 7864-7867 IN denotes for
T9321 7868-7870 DT denotes an
T9322 7871-7880 JJ denotes autocrine
T9323 7881-7886 NN denotes BMP-6
T9324 7887-7891 NN denotes loop
T9325 7892-7894 IN denotes in
T9326 7895-7900 JJ denotes human
T9327 7901-7902 NN denotes B
T9328 7903-7908 NN denotes cells
T9329 7910-7912 PRP denotes We
T9330 7913-7921 VB denotes analysed
T9331 7922-7925 DT denotes the
T9332 7926-7936 NN denotes expression
T9333 7937-7942 NN denotes BMP-6
T9334 7943-7947 NN denotes mRNA
T9335 7948-7950 IN denotes in
T9336 7951-7961 JJ denotes peripheral
T9337 7962-7967 NN denotes blood
T9338 7968-7969 NN denotes B
T9339 7970-7975 NN denotes cells
T9340 7976-7978 IN denotes by
T9341 7979-7988 JJ denotes real-time
T9342 7989-7992 NN denotes PCR
T9343 7992-7993 -COMMA- denotes ,
T9344 7994-7997 CC denotes and
T9345 7998-8004 NN denotes report
T9346 8005-8009 RB denotes here
T9347 8010-8013 DT denotes the
T9348 8014-8026 NN denotes upregulation
T9349 8027-8029 IN denotes of
T9350 8030-8040 JJ denotes endogenous
T9351 8041-8046 NN denotes BMP-6
T9352 8047-8058 NN denotes transcripts
T9353 8059-8064 IN denotes after
T9354 8065-8076 NN denotes stimulation
T9355 8077-8081 IN denotes with
T9356 8082-8085 NN denotes FCS
T9357 8085-8086 -COMMA- denotes ,
T9358 8087-8092 JJ denotes human
T9359 8093-8101 NN denotes AB-serum
T9360 8102-8105 CC denotes and
T9361 8105-8106 -COMMA- denotes ,
T9362 8107-8111 RB denotes most
T9363 8112-8123 RB denotes importantly
T9364 8123-8124 -COMMA- denotes ,
T9365 8125-8133 JJ denotes anti-IgM
T9366 8135-8142 RB denotes However
T9367 8142-8143 -COMMA- denotes ,
T9368 8144-8147 PRP-DOLLAR- denotes our
T9369 8148-8156 NN denotes attempts
T9370 8157-8159 TO denotes to
T9371 8160-8165 VB denotes study
T9372 8166-8171 NN denotes BMP-6
T9373 8172-8179 NN denotes protein
T9374 8180-8186 NN denotes levels
T9375 8187-8191 VB denotes were
T9376 8192-8204 JJ denotes unsuccessful
T9377 8205-8208 JJ denotes due
T9378 8209-8211 TO denotes to
T9379 8212-8220 NN denotes problems
T9380 8221-8225 IN denotes with
T9381 8226-8236 JJ denotes unspecific
T9382 8237-8244 NN denotes binding
T9383 8245-8247 IN denotes of
T9384 8248-8251 DT denotes the
T9385 8252-8262 JJ denotes anti-BMP-6
T9386 8263-8273 NN denotes antibodies
T9387 8274-8280 VB denotes tested
T9388 8280-8281 -COMMA- denotes ,
T9389 8282-8285 CC denotes and
T9390 8286-8290 NN denotes lack
T9391 8291-8293 IN denotes of
T9392 8294-8302 JJ denotes specific
T9393 8303-8311 NN denotes staining
T9394 8312-8314 IN denotes in
T9395 8315-8322 NN denotes control
T9396 8323-8328 NN denotes cells
T9397 8329-8334 VB denotes known
T9398 8335-8337 TO denotes to
T9399 8338-8345 VB denotes express
T9400 8346-8351 NN denotes BMP-6
T9401 8352-8356 NN denotes mRNA
T9402 8358-8360 IN denotes In
T9403 8361-8369 NN denotes contrast
T9404 8369-8370 -COMMA- denotes ,
T9405 8371-8374 DT denotes the
T9406 8375-8386 JJ denotes recombinant
T9407 8387-8394 NN denotes protein
T9408 8395-8398 VB denotes was
T9409 8399-8406 RB denotes readily
T9410 8407-8415 VB denotes detected
T9411 8417-8419 IN denotes In
T9412 8420-8424 DT denotes that
T9413 8425-8432 NN denotes respect
T9414 8432-8433 -COMMA- denotes ,
T9415 8434-8437 JJ denotes few
T9416 8438-8451 NN denotes investigators
T9417 8452-8456 VB denotes have
T9418 8457-8465 VB denotes detected
T9419 8466-8471 NN denotes BMP-6
T9420 8472-8479 NN denotes protein
T9421 8480-8482 IN denotes in
T9422 8483-8489 NN denotes humans
T9423 8489-8490 -COMMA- denotes ,
T9424 8491-8501 RB denotes especially
T9425 8502-8504 IN denotes in
T9426 8505-8519 JJ denotes non-pathogenic
T9427 8520-8526 NN denotes tissue
T9428 8528-8531 DT denotes The
T9429 8532-8543 NN denotes possibility
T9430 8544-8546 IN denotes of
T9431 8547-8552 NN denotes BMP-6
T9432 8553-8563 NN denotes production
T9433 8564-8566 IN denotes in
T9434 8567-8572 JJ denotes human
T9435 8573-8580 NN denotes B-cells
T9436 8581-8583 VB denotes is
T9437 8584-8586 IN denotes in
T9438 8587-8591 NN denotes line
T9439 8592-8596 IN denotes with
T9440 8597-8598 DT denotes a
T9441 8599-8605 JJ denotes recent
T9442 8606-8610 NN denotes work
T9443 8611-8615 WDT denotes that
T9444 8616-8624 VB denotes reported
T9445 8625-8628 DT denotes the
T9446 8629-8639 NN denotes production
T9447 8640-8642 IN denotes of
T9448 8643-8648 NN denotes BMP-6
T9449 8649-8651 IN denotes in
T9450 8652-8657 NN denotes mouse
T9451 8658-8659 NN denotes B
T9452 8660-8665 NN denotes cells
T9453 8665-8666 -COMMA- denotes ,
T9454 8667-8679 VB denotes infiltrating
T9455 8680-8683 DT denotes the
T9456 8684-8688 NN denotes bone
T9457 8689-8695 NN denotes marrow
T9458 8696-8698 IN denotes of
T9459 8699-8703 NN denotes mice
T9460 8704-8708 IN denotes with
T9461 8709-8721 JJ denotes inflammatory
T9462 8722-8731 NN denotes arthritis
T9463 8732-8733 -LRB- denotes [
T9464 8733-8735 CD denotes 43
T9465 8735-8736 -RRB- denotes ]
T9466 8738-8740 IN denotes In
T9467 8741-8745 DT denotes this
T9468 8746-8751 NN denotes study
T9469 8751-8752 -COMMA- denotes ,
T9470 8753-8754 DT denotes a
T9471 8755-8759 NN denotes role
T9472 8760-8763 IN denotes for
T9473 8764-8768 NN denotes BMPs
T9474 8769-8771 IN denotes in
T9475 8772-8775 DT denotes the
T9476 8776-8789 JJ denotes inflammatoric
T9477 8790-8797 NN denotes process
T9478 8798-8800 IN denotes of
T9479 8801-8810 NN denotes arthritis
T9480 8811-8814 VB denotes was
T9481 8815-8824 VB denotes suggested
T9482 8826-8829 DT denotes The
T9483 8830-8842 NN denotes upregulation
T9484 8843-8845 IN denotes of
T9485 8846-8849 DT denotes the
T9486 8850-8867 NN denotes BMP-6-transcripts
T9487 8868-8873 IN denotes after
T9488 8874-8890 NN denotes IgM-crosslinking
T9489 8891-8893 VB denotes is
T9490 8894-8896 IN denotes of
T9491 8897-8913 JJ denotes pathophysiologic
T9492 8914-8922 NN denotes interest
T9493 8923-8924 -LRB- denotes [
T9494 8924-8926 CD denotes 12
T9495 8926-8927 -RRB- denotes ]
T9496 8929-8930 DT denotes A
T9497 8931-8935 NN denotes loss
T9498 8936-8938 IN denotes of
T9499 8939-8959 NN denotes TGF-β-responsiveness
T9500 8960-8963 VB denotes has
T9501 8964-8968 VB denotes been
T9502 8969-8978 VB denotes suggested
T9503 8979-8981 TO denotes to
T9504 8982-8984 VB denotes be
T9505 8985-8986 DT denotes a
T9506 8987-8995 JJ denotes critical
T9507 8996-9008 NN denotes contribution
T9508 9009-9011 TO denotes to
T9509 9012-9021 JJ denotes malignant
T9510 9022-9036 NN denotes transformation
T9511 9037-9038 -LRB- denotes [
T9512 9038-9043 CD denotes 47,48
T9513 9043-9044 -RRB- denotes ]
T9514 9045-9048 CC denotes and
T9515 9049-9056 JJ denotes similar
T9516 9057-9066 JJ denotes oncogenic
T9517 9067-9077 NN denotes mechanisms
T9518 9078-9082 VB denotes have
T9519 9083-9087 VB denotes been
T9520 9088-9098 VB denotes postulated
T9521 9099-9102 IN denotes for
T9522 9103-9107 NN denotes BMPs
T9523 9109-9114 NN denotes Lines
T9524 9115-9117 IN denotes of
T9525 9118-9126 NN denotes evidence
T9526 9127-9134 VB denotes suggest
T9527 9135-9136 -LRB- denotes [
T9528 9136-9138 CD denotes 49
T9529 9138-9139 -RRB- denotes ]
T9530 9140-9144 IN denotes that
T9531 9145-9147 IN denotes at
T9532 9148-9153 JJ denotes early
T9533 9154-9160 NN denotes stages
T9534 9161-9163 IN denotes of
T9535 9164-9178 NN denotes carcinogenesis
T9536 9178-9179 -COMMA- denotes ,
T9537 9180-9185 NN denotes BMP-6
T9538 9186-9188 VB denotes is
T9539 9189-9192 RB denotes not
T9540 9193-9194 DT denotes a
T9541 9195-9201 NN denotes tumour
T9542 9202-9210 NN denotes promoter
T9543 9210-9211 -COMMA- denotes ,
T9544 9212-9215 CC denotes but
T9545 9216-9226 VB denotes suppresses
T9546 9227-9233 JJ denotes benign
T9547 9234-9237 CC denotes and
T9548 9238-9247 JJ denotes malignant
T9549 9248-9254 NN denotes tumour
T9550 9255-9264 NN denotes outgrowth
T9551 9266-9271 DT denotes These
T9552 9272-9280 NN denotes findings
T9553 9281-9284 VB denotes are
T9554 9285-9287 IN denotes in
T9555 9288-9292 JJ denotes good
T9556 9293-9302 NN denotes agreement
T9557 9303-9307 IN denotes with
T9558 9308-9316 JJ denotes previous
T9559 9317-9325 NN denotes findings
T9560 9326-9329 IN denotes for
T9561 9330-9335 JJ denotes other
T9562 9336-9341 NN denotes TGF-β
T9563 9342-9348 NN denotes family
T9564 9349-9356 NN denotes members
T9565 9356-9357 -COMMA- denotes ,
T9566 9358-9367 VB denotes including
T9567 9368-9374 NN denotes TGF-β1
T9568 9375-9378 CC denotes and
T9569 9379-9384 NN denotes BMP-4
T9570 9385-9386 -LRB- denotes [
T9571 9386-9388 CD denotes 50
T9572 9388-9389 -RRB- denotes ]
T9573 9389-9390 -COMMA- denotes ,
T9574 9391-9401 VB denotes indicating
T9575 9402-9406 IN denotes that
T9576 9407-9415 JJ denotes cellular
T9577 9416-9423 NN denotes context
T9578 9424-9426 IN denotes of
T9579 9427-9430 DT denotes the
T9580 9431-9434 NN denotes BMP
T9581 9435-9441 NN denotes target
T9582 9442-9446 NN denotes cell
T9583 9447-9452 MD denotes might
T9584 9453-9459 VB denotes define
T9585 9460-9463 DT denotes the
T9586 9464-9471 JJ denotes various
T9587 9472-9480 VB denotes observed
T9588 9481-9488 NN denotes effects
T9589 9490-9492 IN denotes In
T9590 9493-9501 NN denotes contrast
T9591 9502-9504 TO denotes to
T9592 9505-9508 DT denotes the
T9593 9509-9521 NN denotes upregulation
T9594 9522-9524 IN denotes of
T9595 9525-9530 NN denotes BMP-6
T9596 9531-9541 NN denotes transcript
T9597 9542-9544 IN denotes in
T9598 9545-9546 NN denotes B
T9599 9547-9552 NN denotes cells
T9600 9552-9553 -COMMA- denotes ,
T9601 9554-9556 PRP denotes we
T9602 9557-9561 VB denotes were
T9603 9562-9565 RB denotes not
T9604 9566-9570 JJ denotes able
T9605 9571-9573 TO denotes to
T9606 9574-9580 VB denotes detect
T9607 9581-9586 NN denotes BMP-6
T9608 9587-9598 NN denotes transcripts
T9609 9599-9601 IN denotes in
T9610 9602-9607 JJ denotes human
T9611 9608-9618 JJ denotes peripheral
T9612 9619-9624 NN denotes blood
T9613 9625-9629 JJ denotes CD4+
T9614 9630-9632 CC denotes or
T9615 9633-9637 JJ denotes CD8+
T9616 9638-9639 NN denotes T
T9617 9640-9645 NN denotes cells
T9618 9646-9647 -LRB- denotes (
T9619 9647-9654 VB denotes resting
T9620 9655-9657 CC denotes or
T9621 9658-9668 VB denotes stimulated
T9622 9669-9673 IN denotes with
T9623 9674-9682 JJ denotes anti-CD3
T9624 9683-9686 CC denotes and
T9625 9687-9696 JJ denotes anti-CD28
T9626 9696-9697 -COLON- denotes ;
T9627 9698-9702 NN denotes data
T9628 9703-9706 RB denotes not
T9629 9707-9712 VB denotes shown
T9630 9712-9713 -RRB- denotes )
T9631 9713-9714 -COMMA- denotes ,
T9632 9715-9725 JJ denotes consistent
T9633 9726-9730 IN denotes with
T9634 9731-9734 DT denotes the
T9635 9735-9743 NN denotes findings
T9636 9744-9746 IN denotes in
T9637 9747-9748 NN denotes T
T9638 9749-9753 NN denotes cell
T9639 9754-9759 NN denotes lines
T9640 9760-9761 -LRB- denotes [
T9641 9761-9763 CD denotes 20
T9642 9763-9764 -RRB- denotes ]
T9643 9765-9768 CC denotes and
T9644 9769-9770 NN denotes T
T9645 9771-9776 NN denotes cells
T9646 9777-9779 IN denotes in
T9647 9780-9784 NN denotes mice
T9648 9785-9786 -LRB- denotes [
T9649 9786-9788 CD denotes 43
T9650 9788-9789 -RRB- denotes ]
T9651 9791-9796 JJ denotes Other
T9652 9797-9806 JJ denotes potential
T9653 9807-9812 NN denotes BMP-6
T9654 9813-9820 NN denotes sources
T9655 9821-9824 IN denotes for
T9656 9825-9831 JJ denotes mature
T9657 9832-9833 NN denotes B
T9658 9834-9839 NN denotes cells
T9659 9840-9842 FW denotes in
T9660 9843-9847 FW denotes vivo
T9661 9848-9853 MD denotes might
T9662 9854-9856 VB denotes be
T9663 9857-9862 JJ denotes other
T9664 9863-9868 NN denotes cells
T9665 9869-9871 IN denotes of
T9666 9872-9875 DT denotes the
T9667 9876-9882 JJ denotes immune
T9668 9883-9889 NN denotes system
T9669 9890-9892 CC denotes or
T9670 9893-9899 NN denotes tissue
T9671 9900-9904 IN denotes with
T9672 9905-9912 NN denotes contact
T9673 9913-9915 TO denotes to
T9674 9916-9919 DT denotes the
T9675 9920-9933 JJ denotes hematopoietic
T9676 9934-9940 NN denotes system
T9677 9942-9945 CD denotes One
T9678 9946-9950 RB denotes well
T9679 9951-9961 VB denotes recognized
T9680 9962-9968 NN denotes source
T9681 9969-9972 IN denotes for
T9682 9973-9978 NN denotes BMP-6
T9683 9979-9989 NN denotes production
T9684 9990-9992 VB denotes is
T9685 9993-9996 DT denotes the
T9686 9997-10002 JJ denotes human
T9687 10003-10007 NN denotes bone
T9688 10008-10011 CC denotes and
T9689 10012-10016 NN denotes bone
T9690 10017-10023 NN denotes marrow
T9691 10024-10030 NN denotes stroma
T9692 10031-10032 -LRB- denotes [
T9693 10032-10036 CD denotes 51,8
T9694 10036-10037 -RRB- denotes ]
T9695 10039-10050 RB denotes Furthermore
T9696 10050-10051 -COMMA- denotes ,
T9697 10052-10054 PRP denotes it
T9698 10055-10057 VB denotes is
T9699 10058-10068 JJ denotes noteworthy
T9700 10069-10073 IN denotes that
T9701 10074-10079 JJ denotes human
T9702 10080-10089 JJ denotes umbilical
T9703 10090-10094 NN denotes vein
T9704 10095-10106 JJ denotes endothelial
T9705 10107-10112 NN denotes cells
T9706 10113-10114 -LRB- denotes (
T9707 10114-10119 NN denotes HUVEC
T9708 10119-10120 -RRB- denotes )
T9709 10121-10127 RB denotes highly
T9710 10128-10135 VB denotes express
T9711 10136-10141 NN denotes BMP-6
T9712 10142-10146 NN denotes mRNA
T9713 10147-10148 -LRB- denotes [
T9714 10148-10150 CD denotes 52
T9715 10150-10151 -RRB- denotes ]
T9716 10151-10152 -COMMA- denotes ,
T9717 10153-10156 CC denotes and
T9718 10157-10165 JJ denotes vascular
T9719 10166-10177 NN denotes endothelium
T9720 10178-10181 VB denotes has
T9721 10182-10186 VB denotes been
T9722 10187-10195 VB denotes reported
T9723 10196-10198 TO denotes to
T9724 10199-10206 VB denotes produce
T9725 10207-10212 NN denotes BMP-6
T9726 10213-10214 -LRB- denotes [
T9727 10214-10216 CD denotes 53
T9728 10216-10217 -RRB- denotes ]
T9729 10219-10224 DT denotes These
T9730 10225-10232 NN denotes studies
T9731 10233-10238 MD denotes might
T9732 10239-10244 VB denotes imply
T9733 10245-10246 DT denotes a
T9734 10247-10251 NN denotes role
T9735 10252-10255 IN denotes for
T9736 10256-10261 NN denotes BMP-6
T9737 10262-10264 IN denotes in
T9738 10265-10281 JJ denotes transendothelial
T9739 10282-10291 NN denotes migration
T9740 10292-10294 IN denotes of
T9741 10295-10296 NN denotes B
T9742 10297-10302 NN denotes cells
T9743 10304-10309 NN denotes BMP-6
T9744 10310-10314 NN denotes mRNA
T9745 10315-10318 VB denotes has
T9746 10319-10323 VB denotes been
T9747 10324-10336 VB denotes demonstrated
T9748 10337-10339 IN denotes in
T9749 10340-10346 JJ denotes murine
T9750 10347-10357 NN denotes macrophage
T9751 10358-10362 NN denotes cell
T9752 10363-10368 NN denotes lines
T9753 10368-10369 -COMMA- denotes ,
T9754 10370-10373 CC denotes but
T9755 10374-10377 RB denotes not
T9756 10378-10380 IN denotes in
T9757 10381-10387 NN denotes humans
T9758 10388-10389 -LRB- denotes [
T9759 10389-10391 CD denotes 54
T9760 10391-10392 -RRB- denotes ]
T9761 10394-10396 IN denotes In
T9762 10397-10407 NN denotes accordance
T9763 10408-10412 IN denotes with
T9764 10413-10418 DT denotes these
T9765 10419-10427 NN denotes findings
T9766 10427-10428 -COMMA- denotes ,
T9767 10429-10434 JJ denotes other
T9768 10435-10440 JJ denotes human
T9769 10441-10445 NN denotes cell
T9770 10446-10451 NN denotes lines
T9772 10455-10465 NN denotes neutrophil
T9773 10466-10469 CC denotes and
T9774 10470-10479 JJ denotes monocytic
T9775 10480-10486 NN denotes origin
T9776 10487-10491 VB denotes have
T9777 10492-10496 VB denotes been
T9778 10497-10506 VB denotes described
T9779 10507-10509 TO denotes to
T9780 10510-10512 VB denotes be
T9781 10513-10521 JJ denotes negative
T9782 10522-10525 IN denotes for
T9783 10526-10529 DT denotes the
T9784 10530-10535 NN denotes BMP-6
T9785 10536-10546 NN denotes transcript
T9786 10547-10548 -LRB- denotes [
T9787 10548-10550 CD denotes 20
T9788 10550-10551 -RRB- denotes ]
T9789 10553-10555 TO denotes To
T9790 10556-10559 PRP-DOLLAR- denotes our
T9791 10560-10569 NN denotes knowledge
T9792 10569-10570 -COMMA- denotes ,
T9793 10571-10576 EX denotes there
T9794 10577-10579 VB denotes is
T9795 10580-10589 RB denotes currently
T9796 10590-10592 DT denotes no
T9797 10593-10599 NN denotes report
T9798 10600-10605 IN denotes about
T9799 10606-10611 NN denotes BMP-6
T9800 10612-10622 NN denotes production
T9801 10623-10625 IN denotes of
T9802 10626-10631 JJ denotes human
T9803 10632-10641 JJ denotes dendritic
T9804 10642-10647 NN denotes cells
T9771 10452-10454 IN denotes of
R5970 T7966 T7965 arg1Of studies,Recent
R5971 T7966 T7967 arg1Of studies,have
R5972 T7966 T7968 arg1Of studies,demonstrated
R5973 T7968 T7967 arg2Of demonstrated,have
R5974 T7968 T7993 arg1Of demonstrated,but
R5975 T7971 T7970 arg1Of role,important
R5976 T7971 T7972 arg1Of role,for
R5977 T7971 T7976 arg1Of role,in
R5978 T7971 T7986 arg1Of role,and
R5979 T7975 T7972 arg2Of members,for
R5980 T7975 T7973 arg1Of members,BMP
R5981 T7975 T7974 arg1Of members,superfamily
R5982 T7979 T7977 arg1Of cells,hematopoietic
R5983 T7979 T7978 arg1Of cells,stem
R5984 T7979 T7980 arg1Of cells,","
R5985 T7980 T7976 arg2Of ",",in
R5986 T7982 T7980 arg2Of thymocytes,","
R5987 T7982 T7981 arg1Of thymocytes,early
R5988 T7982 T7983 arg1Of thymocytes,[
R5989 T7984 T7983 arg2Of "6,7",[
R5990 T7985 T7983 arg3Of ],[
R5991 T7986 T7968 arg2Of and,demonstrated
R5992 T7986 T7969 arg1Of and,an
R5993 T7988 T7986 arg2Of malignancies,and
R5994 T7988 T7987 arg1Of malignancies,B-cell
R5995 T7988 T7989 arg1Of malignancies,[
R5996 T7990 T7989 arg2Of "8,11,12",[
R5997 T7991 T7989 arg3Of ],[
R5998 T7993 T7992 arg1Of but,","
R5999 T7995 T7994 arg1Of role,a
R6000 T7995 T7996 arg1Of role,for
R6001 T7995 T8003 arg1Of role,has
R6002 T7995 T8006 arg1Of role,been
R6003 T7995 T8007 arg2Of role,reported
R6004 T7997 T7996 arg2Of BMPs,for
R6005 T7997 T7998 arg1Of BMPs,in
R6006 T8002 T7998 arg2Of cells,in
R6007 T8002 T7999 arg1Of cells,normal
R6008 T8002 T8000 arg1Of cells,human
R6009 T8002 T8001 arg1Of cells,B
R6010 T8007 T7993 arg2Of reported,but
R6011 T8007 T8003 arg2Of reported,has
R6012 T8007 T8004 arg1Of reported,previously
R6013 T8007 T8005 arg1Of reported,not
R6014 T8007 T8006 arg2Of reported,been
R6015 T8010 T8008 arg1Of study,The
R6016 T8010 T8009 arg1Of study,present
R6017 T8010 T8011 arg1Of study,demonstrated
R6018 T8014 T8013 arg1Of antiproliferative,significant
R6019 T8015 T8011 arg2Of effect,demonstrated
R6020 T8015 T8012 arg1Of effect,a
R6021 T8015 T8014 arg1Of effect,antiproliferative
R6022 T8015 T8016 arg1Of effect,of
R6023 T8015 T8018 arg1Of effect,in
R6024 T8017 T8016 arg2Of BMP-6,of
R6025 T8023 T8018 arg2Of cells,in
R6026 T8023 T8019 arg1Of cells,peripheral
R6027 T8023 T8020 arg1Of cells,blood
R6028 T8023 T8021 arg1Of cells,CD19+
R6029 T8023 T8022 arg1Of cells,B
R6030 T8026 T8027 arg1Of BMP-6,induced
R6031 T8027 T8024 arg1Of induced,Additionally
R6032 T8027 T8025 arg1Of induced,","
R6033 T8027 T8030 arg1Of induced,in
R6034 T8027 T8038 arg1Of induced,in
R6035 T8029 T8027 arg2Of death,induced
R6036 T8029 T8028 arg1Of death,cell
R6037 T8030 T8037 arg1Of in,as
R6038 T8034 T8030 arg2Of cells,in
R6039 T8034 T8031 arg1Of cells,CD27+
R6040 T8034 T8032 arg1Of cells,memory
R6041 T8034 T8033 arg1Of cells,B
R6042 T8037 T8035 arg1Of as,as
R6043 T8037 T8036 arg1Of as,well
R6044 T8038 T8037 arg2Of in,as
R6045 T8043 T8038 arg2Of line,in
R6046 T8043 T8039 arg1Of line,a
R6047 T8043 T8040 arg1Of line,Burkitt
R6048 T8043 T8041 arg1Of line,lymphoma
R6049 T8043 T8042 arg1Of line,cell
R6050 T8043 T8044 arg1Of line,(
R6051 T8045 T8044 arg2Of Ramos,(
R6052 T8046 T8044 arg3Of ),(
R6053 T8049 T8050 arg1Of BMP-6,induced
R6054 T8050 T8047 arg1Of induced,Importantly
R6055 T8050 T8048 arg1Of induced,","
R6056 T8052 T8053 arg1Of rapid,and
R6057 T8054 T8053 arg2Of marked,and
R6058 T8055 T8050 arg2Of increase,induced
R6059 T8055 T8051 arg1Of increase,a
R6060 T8055 T8052 arg1Of increase,rapid
R6061 T8055 T8054 arg1Of increase,marked
R6062 T8055 T8056 arg1Of increase,in
R6063 T8058 T8056 arg2Of phosphorylation,in
R6064 T8058 T8057 arg1Of phosphorylation,Smad-1/5/8
R6065 T8063 T8062 arg1Of induced,BMP-6
R6066 T8065 T8061 arg1Of phosphorylation,the
R6067 T8065 T8063 arg1Of phosphorylation,induced
R6068 T8065 T8064 arg1Of phosphorylation,Smad
R6069 T8065 T8066 arg1Of phosphorylation,was
R6070 T8065 T8067 arg2Of phosphorylation,followed
R6071 T8067 T8059 arg1Of followed,Furthermore
R6072 T8067 T8060 arg1Of followed,","
R6073 T8067 T8066 arg2Of followed,was
R6074 T8071 T8067 arg1Of upregulation,followed
R6075 T8071 T8068 arg2Of upregulation,by
R6076 T8071 T8069 arg1Of upregulation,a
R6077 T8071 T8070 arg1Of upregulation,selective
R6078 T8071 T8072 arg1Of upregulation,of
R6079 T8074 T8073 arg1Of mRNA,Id1
R6080 T8074 T8075 arg1Of mRNA,and
R6081 T8075 T8072 arg2Of and,of
R6082 T8078 T8075 arg2Of protein,and
R6083 T8078 T8076 arg1Of protein,subsequent
R6084 T8078 T8077 arg1Of protein,Id1
R6085 T8082 T8079 arg2Of study,In
R6086 T8082 T8080 arg1Of study,the
R6087 T8082 T8081 arg1Of study,present
R6088 T8087 T8084 arg1Of effect,the
R6089 T8087 T8085 arg2Of effect,demonstrated
R6090 T8087 T8086 arg1Of effect,antiproliferative
R6091 T8087 T8088 arg1Of effect,of
R6092 T8087 T8090 arg1Of effect,in
R6093 T8087 T8095 arg1Of effect,was
R6094 T8087 T8096 arg1Of effect,significant
R6095 T8087 T8098 arg1Of effect,dose-dependent
R6096 T8089 T8088 arg2Of BMP-6,of
R6097 T8094 T8090 arg2Of cells,in
R6098 T8094 T8091 arg1Of cells,anti-IgM
R6099 T8094 T8092 arg2Of cells,treated
R6100 T8094 T8093 arg1Of cells,B
R6101 T8095 T8079 arg1Of was,In
R6102 T8095 T8083 arg1Of was,","
R6103 T8096 T8097 arg1Of significant,and
R6104 T8097 T8095 arg2Of and,was
R6105 T8098 T8097 arg2Of dose-dependent,and
R6106 T8103 T8101 arg1Of effect,the
R6107 T8103 T8102 arg1Of effect,anti-proliferative
R6108 T8103 T8104 arg1Of effect,of
R6109 T8103 T8106 arg1Of effect,could
R6110 T8103 T8107 arg1Of effect,be
R6111 T8103 T8109 arg2Of effect,neutralized
R6112 T8103 T8118 arg1Of effect,Noggin.
R6113 T8105 T8104 arg2Of BMP-6,of
R6114 T8109 T8106 arg2Of neutralized,could
R6115 T8109 T8107 arg2Of neutralized,be
R6116 T8109 T8108 arg1Of neutralized,completely
R6117 T8109 T8117 arg1Of neutralized,","
R6118 T8112 T8109 arg1Of use,neutralized
R6119 T8112 T8110 arg2Of use,by
R6120 T8112 T8111 arg1Of use,the
R6121 T8112 T8113 arg1Of use,of
R6122 T8116 T8113 arg2Of inhibitor,of
R6123 T8116 T8114 arg1Of inhibitor,a
R6124 T8116 T8115 arg1Of inhibitor,natural
R6125 T8117 T8099 arg1Of ",",Importantly
R6126 T8117 T8100 arg1Of ",",","
R6127 T8117 T8125 arg1Of ",",","
R6128 T8117 T8126 modOf ",",showing
R6129 T8118 T8117 arg2Of Noggin.,","
R6130 T8119 T8120 arg1Of This,is
R6131 T8119 T8121 arg1Of This,in
R6132 T8120 T8118 arg2Of is,Noggin.
R6133 T8121 T8120 arg2Of in,is
R6134 T8122 T8121 arg2Of line,in
R6135 T8122 T8123 arg1Of line,with
R6136 T8124 T8123 arg2Of others,with
R6137 T8128 T8129 arg1Of Noggin,can
R6138 T8128 T8130 arg1Of Noggin,function
R6139 T8130 T8126 arg2Of function,showing
R6140 T8130 T8127 arg1Of function,that
R6141 T8130 T8129 arg2Of function,can
R6142 T8130 T8131 arg1Of function,as
R6143 T8130 T8135 arg1Of function,[
R6144 T8134 T8131 arg2Of antagonist,as
R6145 T8134 T8132 arg1Of antagonist,a
R6146 T8134 T8133 arg1Of antagonist,BMP-6
R6147 T8136 T8135 arg2Of "21,22",[
R6148 T8137 T8135 arg3Of ],[
R6149 T8139 T8138 arg2Of addition,In
R6150 T8142 T8141 arg1Of combination,the
R6151 T8142 T8143 arg1Of combination,of
R6152 T8142 T8151 arg1Of combination,neutralized
R6153 T8145 T8144 arg1Of BMP-RIB-Fc,soluble
R6154 T8145 T8146 arg1Of BMP-RIB-Fc,and
R6155 T8146 T8143 arg2Of and,of
R6156 T8149 T8146 arg2Of proteins,and
R6157 T8149 T8147 arg1Of proteins,BMP-RII-Fc
R6158 T8149 T8148 arg1Of proteins,fusion
R6159 T8151 T8138 arg1Of neutralized,In
R6160 T8151 T8140 arg1Of neutralized,","
R6161 T8151 T8150 arg1Of neutralized,also
R6162 T8154 T8151 arg2Of effect,neutralized
R6163 T8154 T8152 arg1Of effect,the
R6164 T8154 T8153 arg1Of effect,anti-proliferative
R6165 T8154 T8155 arg1Of effect,of
R6166 T8154 T8157 arg1Of effect,in
R6167 T8156 T8155 arg2Of BMP-6,of
R6168 T8160 T8157 arg2Of cells,in
R6169 T8160 T8158 arg1Of cells,human
R6170 T8160 T8159 arg1Of cells,B
R6171 T8164 T8163 arg1Of for,as
R6172 T8168 T8164 arg2Of members,for
R6173 T8168 T8165 arg1Of members,other
R6174 T8168 T8166 arg1Of members,TGF
R6175 T8168 T8167 arg1Of members,family
R6176 T8171 T8170 arg1Of effects,bifunctional
R6177 T8171 T8172 arg1Of effects,have
R6178 T8171 T8174 arg1Of effects,been
R6179 T8171 T8175 arg2Of effects,demonstrated
R6180 T8175 T8161 arg1Of demonstrated,Interestingly
R6181 T8175 T8162 arg1Of demonstrated,","
R6182 T8175 T8164 arg1Of demonstrated,for
R6183 T8175 T8169 arg1Of demonstrated,","
R6184 T8175 T8172 arg2Of demonstrated,have
R6185 T8175 T8173 arg1Of demonstrated,also
R6186 T8175 T8174 arg2Of demonstrated,been
R6187 T8175 T8176 arg1Of demonstrated,for
R6188 T8177 T8176 arg2Of BMPs,for
R6189 T8179 T8180 arg1Of several,of
R6190 T8179 T8183 arg1Of several,have
R6191 T8179 T8184 arg1Of several,been
R6192 T8179 T8185 arg2Of several,shown
R6193 T8179 T8187 arg1Of several,promote
R6194 T8182 T8180 arg2Of BMPs,of
R6195 T8182 T8181 arg1Of BMPs,the
R6196 T8185 T8178 arg2Of shown,Whereas
R6197 T8185 T8183 arg2Of shown,have
R6198 T8185 T8184 arg2Of shown,been
R6199 T8187 T8185 arg3Of promote,shown
R6200 T8187 T8186 arg1Of promote,to
R6201 T8187 T8189 arg1Of promote,in
R6202 T8188 T8187 arg2Of proliferation,promote
R6203 T8192 T8189 arg2Of types,in
R6204 T8192 T8190 arg1Of types,various
R6205 T8192 T8191 arg1Of types,cell
R6206 T8192 T8193 arg1Of types,including
R6207 T8194 T8193 arg2Of condrocytes,including
R6208 T8194 T8195 arg1Of condrocytes,[
R6209 T8196 T8195 arg2Of 23,[
R6210 T8197 T8195 arg3Of ],[
R6211 T8199 T8200 arg1Of liver,[
R6212 T8199 T8203 arg1Of liver,and
R6213 T8201 T8200 arg2Of 24,[
R6214 T8202 T8200 arg3Of ],[
R6215 T8203 T8216 arg1Of and,has
R6216 T8203 T8217 arg1Of and,been
R6217 T8203 T8218 arg2Of and,reported
R6218 T8205 T8204 arg1Of cells,granulosa
R6219 T8205 T8206 arg1Of cells,[
R6220 T8205 T8209 arg1Of cells,","
R6221 T8207 T8206 arg2Of 25,[
R6222 T8208 T8206 arg3Of ],[
R6223 T8209 T8203 arg2Of ",",and
R6224 T8211 T8210 arg1Of effects,antiproliferative
R6225 T8211 T8212 arg1Of effects,and
R6226 T8212 T8209 arg2Of and,","
R6227 T8213 T8212 arg2Of induction,and
R6228 T8213 T8214 arg1Of induction,of
R6229 T8215 T8214 arg2Of apoptosis,of
R6230 T8218 T8178 arg1Of reported,Whereas
R6231 T8218 T8198 arg1Of reported,","
R6232 T8218 T8216 arg2Of reported,has
R6233 T8218 T8217 arg2Of reported,been
R6234 T8218 T8219 arg1Of reported,for
R6235 T8220 T8221 arg1Of B,and
R6236 T8222 T8221 arg2Of T,and
R6237 T8224 T8219 arg2Of cells,for
R6238 T8224 T8220 arg1Of cells,B
R6239 T8224 T8222 arg1Of cells,T
R6240 T8224 T8223 arg1Of cells,lineage
R6241 T8226 T8225 arg1Of effects,Similar
R6242 T8226 T8227 arg1Of effects,as
R6243 T8226 T8240 arg1Of effects,were
R6244 T8226 T8241 arg2Of effects,demonstrated
R6245 T8228 T8227 arg2Of demonstrated,as
R6246 T8228 T8229 arg1Of demonstrated,for
R6247 T8230 T8229 arg2Of BMP-6,for
R6248 T8230 T8231 arg1Of BMP-6,on
R6249 T8234 T8231 arg2Of cells,on
R6250 T8234 T8232 arg1Of cells,human
R6251 T8234 T8233 arg1Of cells,B
R6252 T8234 T8235 arg1Of cells,in
R6253 T8238 T8235 arg2Of study,in
R6254 T8238 T8236 arg1Of study,the
R6255 T8238 T8237 arg1Of study,present
R6256 T8241 T8239 arg1Of demonstrated,","
R6257 T8241 T8240 arg2Of demonstrated,were
R6258 T8241 T8242 arg1Of demonstrated,for
R6259 T8243 T8244 arg1Of BMP-2,","
R6260 T8244 T8246 arg1Of ",",","
R6261 T8245 T8244 arg2Of 4,","
R6262 T8246 T8248 arg1Of ",",and
R6263 T8247 T8246 arg2Of 6,","
R6264 T8248 T8242 arg2Of and,for
R6265 T8248 T8250 arg1Of and,in
R6266 T8249 T8248 arg2Of -7,and
R6267 T8253 T8250 arg2Of cells,in
R6268 T8253 T8251 arg1Of cells,human
R6269 T8253 T8252 arg1Of cells,myeloma
R6270 T8253 T8254 arg1Of cells,[
R6271 T8255 T8254 arg2Of 9-11,[
R6272 T8256 T8254 arg3Of ],[
R6273 T8258 T8257 arg1Of members,Other
R6274 T8258 T8259 arg1Of members,of
R6275 T8258 T8262 arg1Of members,have
R6276 T8258 T8264 arg1Of members,been
R6277 T8258 T8265 arg2Of members,reported
R6278 T8258 T8267 arg1Of members,induce
R6279 T8258 T8270 arg1Of members,including
R6280 T8261 T8259 arg2Of BMP-family,of
R6281 T8261 T8260 arg1Of BMP-family,the
R6282 T8265 T8262 arg2Of reported,have
R6283 T8265 T8263 arg1Of reported,also
R6284 T8265 T8264 arg2Of reported,been
R6285 T8265 T8269 arg1Of reported,","
R6286 T8265 T8270 modOf reported,including
R6287 T8267 T8265 arg3Of induce,reported
R6288 T8267 T8266 arg1Of induce,to
R6289 T8268 T8267 arg2Of apoptosis,induce
R6290 T8270 T8271 arg1Of including,in
R6291 T8275 T8271 arg2Of cells,in
R6292 T8275 T8272 arg1Of cells,mouse
R6293 T8275 T8273 arg1Of cells,B
R6294 T8275 T8274 arg1Of cells,lineage
R6295 T8275 T8276 arg1Of cells,[
R6296 T8277 T8276 arg2Of 26,[
R6297 T8278 T8276 arg3Of ],[
R6298 T8281 T8282 arg1Of BMP-4,inhibits
R6299 T8282 T8279 arg1Of inhibits,Additionally
R6300 T8282 T8280 arg1Of inhibits,","
R6301 T8282 T8285 arg1Of inhibits,[
R6302 T8284 T8282 arg2Of proliferation,inhibits
R6303 T8284 T8283 arg1Of proliferation,thymocyte
R6304 T8286 T8285 arg2Of 6,[
R6305 T8287 T8285 arg3Of ],[
R6306 T8288 T8289 arg1Of Taken,together
R6307 T8292 T8291 arg1Of data,these
R6308 T8292 T8293 arg1Of data,suggest
R6309 T8293 T8288 modOf suggest,Taken
R6310 T8293 T8290 arg1Of suggest,","
R6311 T8296 T8295 arg1Of role,the
R6312 T8296 T8297 arg1Of role,of
R6313 T8296 T8299 arg1Of role,in
R6314 T8296 T8306 arg1Of role,is
R6315 T8296 T8310 arg1Of role,dependent
R6316 T8298 T8297 arg2Of BMPs,of
R6317 T8301 T8299 arg2Of regulation,in
R6318 T8301 T8300 arg1Of regulation,the
R6319 T8301 T8302 arg1Of regulation,of
R6320 T8303 T8304 arg1Of proliferation,and
R6321 T8304 T8302 arg2Of and,of
R6322 T8305 T8304 arg2Of apoptosis,and
R6323 T8306 T8293 arg2Of is,suggest
R6324 T8306 T8294 arg1Of is,that
R6325 T8310 T8306 arg2Of dependent,is
R6326 T8310 T8307 arg1Of dependent,highly
R6327 T8310 T8308 arg1Of dependent,cell
R6328 T8310 T8309 arg1Of dependent,type
R6329 T8312 T8311 arg1Of examine,To
R6330 T8313 T8312 arg2Of how,examine
R6331 T8314 T8315 arg1Of BMP-6,exerts
R6332 T8315 T8313 arg1Of exerts,how
R6333 T8315 T8319 arg1Of exerts,in
R6334 T8318 T8315 arg2Of effects,exerts
R6335 T8318 T8316 arg1Of effects,its
R6336 T8318 T8317 arg1Of effects,functional
R6337 T8321 T8319 arg2Of cells,in
R6338 T8321 T8320 arg1Of cells,B
R6339 T8323 T8312 arg1Of we,examine
R6340 T8323 T8324 arg1Of we,analysed
R6341 T8324 T8311 modOf analysed,To
R6342 T8324 T8322 arg1Of analysed,","
R6343 T8324 T8328 arg1Of analysed,by
R6344 T8327 T8324 arg2Of expression,analysed
R6345 T8327 T8325 arg1Of expression,BMP
R6346 T8327 T8326 arg1Of expression,receptor
R6347 T8331 T8328 arg2Of analysis,by
R6348 T8331 T8329 arg1Of analysis,western
R6349 T8331 T8330 arg1Of analysis,blot
R6350 T8335 T8332 arg1Of cells,Human
R6351 T8335 T8333 arg1Of cells,peripheral
R6352 T8335 T8334 arg1Of cells,B
R6353 T8335 T8336 arg1Of cells,were
R6354 T8335 T8337 arg2Of cells,found
R6355 T8335 T8339 arg1Of cells,express
R6356 T8337 T8336 arg2Of found,were
R6357 T8339 T8337 arg3Of express,found
R6358 T8339 T8338 arg1Of express,to
R6359 T8345 T8346 arg1Of Act-RIA,and
R6360 T8346 T8340 arg1Of and,the
R6361 T8346 T8341 arg1Of and,BMP
R6362 T8346 T8342 arg1Of and,type
R6363 T8346 T8343 arg1Of and,I
R6364 T8346 T8344 arg1Of and,receptors
R6365 T8346 T8349 arg1Of and,and
R6366 T8347 T8346 arg2Of BMP-RIB,and
R6367 T8349 T8339 arg2Of and,express
R6368 T8349 T8348 arg1Of and,","
R6369 T8352 T8350 arg1Of II-receptors,the
R6370 T8352 T8351 arg1Of II-receptors,type
R6371 T8353 T8354 arg1Of BMP-RII,and
R6372 T8354 T8349 arg2Of and,and
R6373 T8354 T8352 arg1Of and,II-receptors
R6374 T8354 T8356 arg1Of and,","
R6375 T8354 T8357 arg1Of and,which
R6376 T8354 T8358 arg1Of and,signal
R6377 T8355 T8354 arg2Of Act-RIIb,and
R6378 T8358 T8359 arg1Of signal,after
R6379 T8360 T8359 arg2Of binding,after
R6380 T8360 T8361 arg1Of binding,of
R6381 T8363 T8361 arg2Of BMPs,of
R6382 T8363 T8362 arg1Of BMPs,several
R6383 T8363 T8364 arg1Of BMPs,","
R6384 T8363 T8365 arg1Of BMPs,including
R6385 T8366 T8365 arg2Of BMP-6,including
R6386 T8366 T8367 arg1Of BMP-6,[
R6387 T8368 T8367 arg2Of "16,13",[
R6388 T8369 T8367 arg3Of ],[
R6389 T8372 T8370 arg1Of explore,To
R6390 T8372 T8371 arg1Of explore,further
R6391 T8372 T8374 arg1Of explore,induced
R6392 T8373 T8372 arg2Of BMP-6,explore
R6393 T8374 T8376 arg1Of induced,","
R6394 T8375 T8374 arg2Of signalling,induced
R6395 T8377 T8378 arg1Of activation,of
R6396 T8377 T8381 arg1Of activation,is
R6397 T8377 T8382 arg1Of activation,possible
R6398 T8380 T8378 arg2Of pathways,of
R6399 T8380 T8379 arg1Of pathways,several
R6400 T8381 T8376 arg2Of is,","
R6401 T8382 T8381 arg2Of possible,is
R6402 T8386 T8383 arg1Of pathway,The
R6403 T8386 T8384 arg1Of pathway,major
R6404 T8386 T8385 arg1Of pathway,signalling
R6405 T8386 T8387 arg2Of pathway,known
R6406 T8386 T8391 arg1Of pathway,is
R6407 T8387 T8388 arg1Of known,to
R6408 T8389 T8388 arg2Of date,to
R6409 T8391 T8390 arg1Of is,","
R6410 T8392 T8391 arg2Of activation,is
R6411 T8392 T8393 arg1Of activation,of
R6412 T8394 T8393 arg2Of R-Smads,of
R6413 T8394 T8395 arg1Of R-Smads,[
R6414 T8396 T8395 arg2Of "13,27",[
R6415 T8397 T8395 arg3Of ],[
R6416 T8400 T8398 arg2Of respect,In
R6417 T8400 T8399 arg1Of respect,that
R6418 T8402 T8403 arg1Of BMPs,have
R6419 T8402 T8404 arg1Of BMPs,been
R6420 T8402 T8405 arg2Of BMPs,shown
R6421 T8402 T8407 arg1Of BMPs,exert
R6422 T8405 T8398 arg1Of shown,In
R6423 T8405 T8401 arg1Of shown,","
R6424 T8405 T8403 arg2Of shown,have
R6425 T8405 T8404 arg2Of shown,been
R6426 T8407 T8405 arg3Of exert,shown
R6427 T8407 T8406 arg1Of exert,to
R6428 T8407 T8410 arg1Of exert,in
R6429 T8407 T8414 arg1Of exert,via
R6430 T8409 T8407 arg2Of effects,exert
R6431 T8409 T8408 arg1Of effects,antiproliferative
R6432 T8413 T8410 arg2Of cells,in
R6433 T8413 T8411 arg1Of cells,B
R6434 T8413 T8412 arg1Of cells,lineage
R6435 T8415 T8414 arg2Of phosphorylation,via
R6436 T8415 T8416 arg1Of phosphorylation,of
R6437 T8417 T8416 arg2Of R-Smad,of
R6438 T8417 T8418 arg1Of R-Smad,[
R6439 T8419 T8418 arg2Of "11,28",[
R6440 T8420 T8418 arg3Of ],[
R6441 T8423 T8424 arg1Of BMP-2,has
R6442 T8423 T8425 arg1Of BMP-2,been
R6443 T8423 T8426 arg2Of BMP-2,shown
R6444 T8423 T8428 arg1Of BMP-2,induce
R6445 T8426 T8421 arg1Of shown,Furthermore
R6446 T8426 T8422 arg1Of shown,","
R6447 T8426 T8424 arg2Of shown,has
R6448 T8426 T8425 arg2Of shown,been
R6449 T8428 T8426 arg3Of induce,shown
R6450 T8428 T8427 arg1Of induce,to
R6451 T8428 T8435 arg1Of induce,[
R6452 T8429 T8428 arg2Of activation,induce
R6453 T8429 T8430 arg1Of activation,of
R6454 T8429 T8432 arg1Of activation,in
R6455 T8431 T8430 arg2Of STAT3,of
R6456 T8434 T8432 arg2Of cells,in
R6457 T8434 T8433 arg1Of cells,myeloma
R6458 T8436 T8435 arg2Of 9,[
R6459 T8437 T8435 arg3Of ],[
R6460 T8440 T8441 arg1Of phosphorylation,of
R6461 T8440 T8443 arg1Of phosphorylation,was
R6462 T8440 T8445 arg2Of phosphorylation,investigated
R6463 T8442 T8441 arg2Of R-Smad,of
R6464 T8445 T8438 arg1Of investigated,However
R6465 T8445 T8439 arg1Of investigated,","
R6466 T8445 T8443 arg2Of investigated,was
R6467 T8445 T8444 arg1Of investigated,not
R6468 T8445 T8446 arg1Of investigated,in
R6469 T8448 T8446 arg2Of study,in
R6470 T8448 T8447 arg1Of study,that
R6471 T8449 T8450 arg1Of BMP-2,has
R6472 T8449 T8452 arg1Of BMP-2,been
R6473 T8449 T8453 arg2Of BMP-2,shown
R6474 T8449 T8455 arg1Of BMP-2,induce
R6475 T8453 T8450 arg2Of shown,has
R6476 T8453 T8451 arg1Of shown,also
R6477 T8453 T8452 arg2Of shown,been
R6478 T8455 T8453 arg3Of induce,shown
R6479 T8455 T8454 arg1Of induce,to
R6480 T8455 T8459 arg1Of induce,[
R6481 T8456 T8455 arg2Of phosphorylation,induce
R6482 T8456 T8457 arg1Of phosphorylation,of
R6483 T8458 T8457 arg2Of p38,of
R6484 T8460 T8459 arg2Of 29,[
R6485 T8461 T8459 arg3Of ],[
R6486 T8464 T8465 arg1Of phosphorylation,of
R6487 T8464 T8471 arg1Of phosphorylation,represent
R6488 T8466 T8467 arg1Of p38,","
R6489 T8467 T8469 arg1Of ",",and
R6490 T8468 T8467 arg2Of STAT3,","
R6491 T8469 T8465 arg2Of and,of
R6492 T8470 T8469 arg2Of Smad1/5/8,and
R6493 T8471 T8462 arg1Of represent,Thus
R6494 T8471 T8463 arg1Of represent,","
R6495 T8474 T8471 arg2Of pathways,represent
R6496 T8474 T8472 arg1Of pathways,important
R6497 T8474 T8473 arg1Of pathways,BMP-signalling
R6498 T8474 T8475 arg1Of pathways,that
R6499 T8474 T8476 arg1Of pathways,mediated
R6500 T8474 T8487 arg1Of pathways,has
R6501 T8474 T8488 arg1Of pathways,been
R6502 T8474 T8489 arg2Of pathways,reported
R6503 T8476 T8481 arg1Of mediated,and
R6504 T8478 T8476 arg2Of effects,mediated
R6505 T8478 T8477 arg1Of effects,the
R6506 T8478 T8479 arg1Of effects,of
R6507 T8480 T8479 arg2Of BMPs,of
R6508 T8482 T8483 arg1Of even,cross-talk
R6509 T8483 T8484 arg1Of cross-talk,between
R6510 T8486 T8484 arg2Of pathways,between
R6511 T8486 T8485 arg1Of pathways,these
R6512 T8489 T8481 arg2Of reported,and
R6513 T8489 T8482 arg1Of reported,even
R6514 T8489 T8487 arg2Of reported,has
R6515 T8489 T8488 arg2Of reported,been
R6516 T8489 T8490 arg1Of reported,[
R6517 T8491 T8490 arg2Of "29,30",[
R6518 T8492 T8490 arg3Of ],[
R6519 T8496 T8493 arg2Of study,In
R6520 T8496 T8494 arg1Of study,the
R6521 T8496 T8495 arg1Of study,present
R6522 T8498 T8499 arg1Of we,were
R6523 T8498 T8501 arg1Of we,able
R6524 T8498 T8503 arg1Of we,detect
R6525 T8499 T8493 arg1Of were,In
R6526 T8499 T8497 arg1Of were,","
R6527 T8499 T8500 arg1Of were,not
R6528 T8501 T8499 arg2Of able,were
R6529 T8503 T8501 arg2Of detect,able
R6530 T8503 T8502 arg1Of detect,to
R6531 T8505 T8503 arg2Of changes,detect
R6532 T8505 T8504 arg1Of changes,BMP-6-induced
R6533 T8505 T8506 arg1Of changes,in
R6534 T8509 T8506 arg2Of status,in
R6535 T8509 T8507 arg1Of status,the
R6536 T8509 T8508 arg1Of status,phosphorylation
R6537 T8509 T8510 arg1Of status,of
R6538 T8509 T8514 arg1Of status,in
R6539 T8511 T8512 arg1Of STAT3,or
R6540 T8512 T8510 arg2Of or,of
R6541 T8513 T8512 arg2Of p38,or
R6542 T8518 T8514 arg2Of cells,in
R6543 T8518 T8515 arg1Of cells,human
R6544 T8518 T8516 arg1Of cells,peripheral
R6545 T8518 T8517 arg1Of cells,B
R6546 T8522 T8523 arg1Of rapid,and
R6547 T8524 T8523 arg2Of marked,and
R6548 T8525 T8521 arg1Of phosphorylation,a
R6549 T8525 T8522 arg1Of phosphorylation,rapid
R6550 T8525 T8524 arg1Of phosphorylation,marked
R6551 T8525 T8526 arg1Of phosphorylation,of
R6552 T8525 T8528 arg1Of phosphorylation,was
R6553 T8525 T8529 arg2Of phosphorylation,revealed
R6554 T8527 T8526 arg2Of Smad1/5/8,of
R6555 T8529 T8519 arg1Of revealed,Instead
R6556 T8529 T8520 arg1Of revealed,","
R6557 T8529 T8528 arg2Of revealed,was
R6558 T8533 T8530 arg2Of study,In
R6559 T8533 T8531 arg1Of study,a
R6560 T8533 T8532 arg1Of study,parallel
R6561 T8535 T8536 arg1Of we,have
R6562 T8535 T8537 arg1Of we,found
R6563 T8537 T8530 arg1Of found,In
R6564 T8537 T8534 arg1Of found,","
R6565 T8537 T8536 arg2Of found,have
R6566 T8540 T8539 arg1Of BMPs,other
R6567 T8540 T8542 arg1Of BMPs,induced
R6568 T8542 T8537 arg2Of induced,found
R6569 T8542 T8538 arg1Of induced,that
R6570 T8542 T8541 arg1Of induced,also
R6571 T8542 T8546 arg1Of induced,in
R6572 T8543 T8542 arg2Of phosphorylation,induced
R6573 T8543 T8544 arg1Of phosphorylation,of
R6574 T8545 T8544 arg2Of Smad1/5/8,of
R6575 T8549 T8546 arg2Of cells,in
R6576 T8549 T8547 arg1Of cells,peripheral
R6577 T8549 T8548 arg1Of cells,B
R6578 T8549 T8550 arg1Of cells,(
R6579 T8551 T8550 arg2Of data,(
R6580 T8551 T8553 arg2Of data,shown
R6581 T8553 T8552 arg1Of shown,not
R6582 T8554 T8550 arg3Of ),(
R6583 T8555 T8556 arg1Of We,are
R6584 T8555 T8558 arg1Of We,pursuing
R6585 T8555 T8562 arg1Of We,identify
R6586 T8558 T8556 arg2Of pursuing,are
R6587 T8558 T8557 arg1Of pursuing,currently
R6588 T8558 T8561 modOf pursuing,to
R6589 T8560 T8558 arg2Of studies,pursuing
R6590 T8560 T8559 arg1Of studies,microarray
R6591 T8562 T8561 arg1Of identify,to
R6592 T8565 T8564 arg1Of pathways,signalling
R6593 T8565 T8566 arg1Of pathways,and
R6594 T8566 T8562 arg2Of and,identify
R6595 T8566 T8563 arg1Of and,the
R6596 T8566 T8569 arg1Of and,that
R6597 T8566 T8570 arg1Of and,are
R6598 T8566 T8572 arg2Of and,regulated
R6599 T8568 T8566 arg2Of genes,and
R6600 T8568 T8567 arg1Of genes,target
R6601 T8572 T8570 arg2Of regulated,are
R6602 T8572 T8571 arg1Of regulated,differently
R6603 T8576 T8572 arg1Of BMPs,regulated
R6604 T8576 T8573 arg2Of BMPs,by
R6605 T8576 T8574 arg1Of BMPs,the
R6606 T8576 T8575 arg1Of BMPs,various
R6607 T8576 T8577 arg1Of BMPs,in
R6608 T8580 T8577 arg2Of cells,in
R6609 T8580 T8578 arg1Of cells,human
R6610 T8580 T8579 arg1Of cells,B
R6611 T8581 T8582 arg1Of Upregulation,of
R6612 T8581 T8584 arg1Of Upregulation,via
R6613 T8581 T8587 arg1Of Upregulation,is
R6614 T8583 T8582 arg2Of Id1,of
R6615 T8586 T8584 arg2Of phosphorylation,via
R6616 T8586 T8585 arg1Of phosphorylation,Smad1/5/8
R6617 T8587 T8601 arg1Of is,and
R6618 T8590 T8587 arg2Of mechanism,is
R6619 T8590 T8588 arg1Of mechanism,a
R6620 T8590 T8589 arg1Of mechanism,known
R6621 T8590 T8591 arg1Of mechanism,for
R6622 T8593 T8591 arg2Of signalling,for
R6623 T8593 T8592 arg1Of signalling,BMP-6
R6624 T8593 T8594 arg1Of signalling,in
R6625 T8597 T8594 arg2Of systems,in
R6626 T8597 T8595 arg1Of systems,other
R6627 T8597 T8596 arg1Of systems,cell
R6628 T8597 T8598 arg1Of systems,[
R6629 T8599 T8598 arg2Of "31,32",[
R6630 T8600 T8598 arg3Of ],[
R6631 T8602 T8603 arg1Of regulation,of
R6632 T8602 T8605 arg1Of regulation,is
R6633 T8602 T8606 arg2Of regulation,thought
R6634 T8602 T8608 arg1Of regulation,be
R6635 T8604 T8603 arg2Of Id-proteins,of
R6636 T8606 T8601 arg2Of thought,and
R6637 T8606 T8605 arg2Of thought,is
R6638 T8608 T8606 arg3Of be,thought
R6639 T8608 T8607 arg1Of be,to
R6640 T8608 T8614 arg1Of be,[
R6641 T8611 T8608 arg2Of mechanism,be
R6642 T8611 T8609 arg1Of mechanism,an
R6643 T8611 T8610 arg1Of mechanism,important
R6644 T8611 T8612 arg1Of mechanism,for
R6645 T8613 T8612 arg2Of Smad-signalling,for
R6646 T8615 T8614 arg2Of 17,[
R6647 T8616 T8614 arg3Of ],[
R6648 T8620 T8617 arg2Of study,In
R6649 T8620 T8618 arg1Of study,the
R6650 T8620 T8619 arg1Of study,present
R6651 T8624 T8622 arg1Of experiments,real-time
R6652 T8624 T8623 arg1Of experiments,RT-PCR
R6653 T8624 T8625 arg1Of experiments,revealed
R6654 T8625 T8617 arg1Of revealed,In
R6655 T8625 T8621 arg1Of revealed,","
R6656 T8625 T8632 arg1Of revealed,in
R6657 T8625 T8636 arg1Of revealed,","
R6658 T8625 T8637 arg1Of revealed,while
R6659 T8629 T8625 arg2Of upregulation,revealed
R6660 T8629 T8626 arg1Of upregulation,a
R6661 T8629 T8627 arg1Of upregulation,specific
R6662 T8629 T8628 arg1Of upregulation,four-fold
R6663 T8629 T8630 arg1Of upregulation,for
R6664 T8631 T8630 arg2Of Id1,for
R6665 T8635 T8632 arg2Of cells,in
R6666 T8635 T8633 arg1Of cells,BMP-6-treated
R6667 T8635 T8634 arg1Of cells,B
R6668 T8639 T8638 arg1Of amount,the
R6669 T8639 T8640 arg1Of amount,of
R6670 T8639 T8642 arg1Of amount,remained
R6671 T8639 T8643 arg1Of amount,unchanged
R6672 T8641 T8640 arg2Of Id2–Id4,of
R6673 T8642 T8637 arg2Of remained,while
R6674 T8643 T8642 arg2Of unchanged,remained
R6675 T8644 T8646 arg1Of In,with
R6676 T8645 T8644 arg2Of agreement,In
R6677 T8647 T8644 arg3Of this,In
R6678 T8651 T8649 arg1Of analysis,western
R6679 T8651 T8650 arg1Of analysis,blot
R6680 T8651 T8652 arg1Of analysis,demonstrated
R6681 T8652 T8644 arg1Of demonstrated,In
R6682 T8652 T8648 arg1Of demonstrated,","
R6683 T8652 T8658 arg1Of demonstrated,","
R6684 T8652 T8659 arg1Of demonstrated,while
R6685 T8654 T8652 arg2Of upregulation,demonstrated
R6686 T8654 T8653 arg1Of upregulation,an
R6687 T8654 T8655 arg1Of upregulation,of
R6688 T8657 T8655 arg2Of protein,of
R6689 T8657 T8656 arg1Of protein,Id1
R6690 T8661 T8660 arg1Of amount,the
R6691 T8661 T8662 arg1Of amount,of
R6692 T8661 T8668 arg1Of amount,remained
R6693 T8661 T8669 arg1Of amount,unchanged
R6694 T8663 T8664 arg1Of Id2,and
R6695 T8665 T8664 arg2Of Id3,and
R6696 T8667 T8662 arg2Of levels,of
R6697 T8667 T8663 arg1Of levels,Id2
R6698 T8667 T8665 arg1Of levels,Id3
R6699 T8667 T8666 arg1Of levels,protein
R6700 T8668 T8659 arg2Of remained,while
R6701 T8669 T8668 arg2Of unchanged,remained
R6702 T8672 T8673 arg1Of Id1,has
R6703 T8672 T8674 arg1Of Id1,been
R6704 T8672 T8675 arg2Of Id1,considered
R6705 T8672 T8678 arg1Of Id1,be
R6706 T8672 T8679 arg2Of Id1,expressed
R6707 T8675 T8673 arg2Of considered,has
R6708 T8675 T8674 arg2Of considered,been
R6709 T8675 T8691 arg1Of considered,and
R6710 T8679 T8675 arg3Of expressed,considered
R6711 T8679 T8676 arg1Of expressed,not
R6712 T8679 T8677 arg1Of expressed,to
R6713 T8679 T8678 arg2Of expressed,be
R6714 T8679 T8680 arg1Of expressed,in
R6715 T8683 T8680 arg2Of stages,in
R6716 T8683 T8681 arg1Of stages,later
R6717 T8683 T8682 arg1Of stages,developmental
R6718 T8683 T8684 arg1Of stages,than
R6719 T8686 T8684 arg2Of cells,than
R6720 T8686 T8685 arg1Of cells,pro-B
R6721 T8686 T8687 arg1Of cells,[
R6722 T8688 T8687 arg2Of "33,34",[
R6723 T8689 T8687 arg3Of ],[
R6724 T8691 T8670 arg1Of and,Previously
R6725 T8691 T8671 arg1Of and,","
R6726 T8691 T8690 arg1Of and,","
R6727 T8694 T8692 arg1Of expression,its
R6728 T8694 T8693 arg1Of expression,constitutive
R6729 T8694 T8695 arg1Of expression,has
R6730 T8694 T8696 arg1Of expression,been
R6731 T8694 T8697 arg2Of expression,reported
R6732 T8694 T8699 arg1Of expression,impair
R6733 T8697 T8691 arg2Of reported,and
R6734 T8697 T8695 arg2Of reported,has
R6735 T8697 T8696 arg2Of reported,been
R6736 T8699 T8697 arg3Of impair,reported
R6737 T8699 T8698 arg1Of impair,to
R6738 T8699 T8704 arg1Of impair,[
R6739 T8703 T8699 arg2Of development,impair
R6740 T8703 T8700 arg1Of development,mouse
R6741 T8703 T8701 arg1Of development,B
R6742 T8703 T8702 arg1Of development,cell
R6743 T8705 T8704 arg2Of 35,[
R6744 T8706 T8704 arg3Of ],[
R6745 T8710 T8709 arg1Of demonstration,our
R6746 T8710 T8711 arg1Of demonstration,of
R6747 T8710 T8726 arg1Of demonstration,is
R6748 T8710 T8727 arg1Of demonstration,of
R6749 T8714 T8711 arg2Of upregulation,of
R6750 T8714 T8712 arg1Of upregulation,the
R6751 T8714 T8713 arg1Of upregulation,time-dependent
R6752 T8714 T8715 arg1Of upregulation,of
R6753 T8714 T8720 arg1Of upregulation,in
R6754 T8717 T8716 arg1Of mRNA,Id1
R6755 T8717 T8718 arg1Of mRNA,and
R6756 T8718 T8715 arg2Of and,of
R6757 T8719 T8718 arg2Of protein,and
R6758 T8725 T8720 arg2Of cells,in
R6759 T8725 T8721 arg1Of cells,mature
R6760 T8725 T8722 arg1Of cells,normal
R6761 T8725 T8723 arg1Of cells,human
R6762 T8725 T8724 arg1Of cells,B
R6763 T8726 T8707 arg1Of is,Therefore
R6764 T8726 T8708 arg1Of is,","
R6765 T8727 T8726 arg2Of of,is
R6766 T8729 T8727 arg2Of interest,of
R6767 T8729 T8728 arg1Of interest,particular
R6768 T8732 T8730 arg2Of respect,In
R6769 T8732 T8731 arg1Of respect,that
R6770 T8735 T8730 arg1Of is,In
R6771 T8735 T8733 arg1Of is,","
R6772 T8736 T8735 arg2Of noteworthy,is
R6773 T8739 T8738 arg1Of signalling,TGF-β
R6774 T8739 T8740 arg1Of signalling,in
R6775 T8739 T8746 arg1Of signalling,induces
R6776 T8741 T8742 arg1Of early,and
R6777 T8743 T8742 arg2Of mature,and
R6778 T8745 T8740 arg2Of cells,in
R6779 T8745 T8741 arg1Of cells,early
R6780 T8745 T8743 arg1Of cells,mature
R6781 T8745 T8744 arg1Of cells,B
R6782 T8746 T8734 arg1Of induces,it
R6783 T8746 T8735 arg1Of induces,is
R6784 T8746 T8736 arg1Of induces,noteworthy
R6785 T8746 T8737 arg1Of induces,that
R6786 T8748 T8749 arg1Of Id2,and
R6787 T8750 T8749 arg2Of Id3,and
R6788 T8751 T8747 arg1Of expression,both
R6789 T8751 T8748 arg1Of expression,Id2
R6790 T8751 T8750 arg1Of expression,Id3
R6791 T8751 T8752 arg1Of expression,[
R6792 T8751 T8756 arg1Of expression,but
R6793 T8753 T8752 arg2Of "36,37",[
R6794 T8754 T8752 arg3Of ],[
R6795 T8756 T8746 arg2Of but,induces
R6796 T8756 T8755 arg1Of but,","
R6797 T8758 T8756 arg2Of Id1,but
R6798 T8758 T8757 arg1Of Id1,not
R6799 T8758 T8759 arg1Of Id1,(
R6800 T8760 T8759 arg2Of data,(
R6801 T8760 T8762 arg2Of data,shown
R6802 T8762 T8761 arg1Of shown,not
R6803 T8763 T8759 arg3Of ),(
R6804 T8767 T8766 arg1Of results,these
R6805 T8767 T8768 arg1Of results,show
R6806 T8768 T8764 arg1Of show,Interestingly
R6807 T8768 T8765 arg1Of show,","
R6808 T8771 T8770 arg1Of members,various
R6809 T8771 T8772 arg1Of members,of
R6810 T8771 T8776 arg1Of members,regulate
R6811 T8775 T8772 arg2Of family,of
R6812 T8775 T8773 arg1Of family,the
R6813 T8775 T8774 arg1Of family,TGF-β
R6814 T8776 T8768 arg2Of regulate,show
R6815 T8776 T8769 arg1Of regulate,that
R6816 T8776 T8779 arg1Of regulate,differently
R6817 T8778 T8776 arg2Of proteins,regulate
R6818 T8778 T8777 arg1Of proteins,Id
R6819 T8780 T8781 arg1Of Id2,and
R6820 T8781 T8783 arg1Of and,are
R6821 T8781 T8784 arg2Of and,considered
R6822 T8781 T8786 arg1Of and,be
R6823 T8782 T8781 arg2Of Id3,and
R6824 T8784 T8783 arg2Of considered,are
R6825 T8786 T8784 arg3Of be,considered
R6826 T8786 T8785 arg1Of be,to
R6827 T8789 T8786 arg2Of proteins,be
R6828 T8789 T8787 arg1Of proteins,the
R6829 T8789 T8788 arg1Of proteins,Id
R6830 T8789 T8791 arg2Of proteins,expressed
R6831 T8791 T8790 arg1Of expressed,mainly
R6832 T8791 T8792 arg1Of expressed,in
R6833 T8795 T8792 arg2Of cells,in
R6834 T8795 T8793 arg1Of cells,mature
R6835 T8795 T8794 arg1Of cells,B
R6836 T8795 T8796 arg1Of cells,[
R6837 T8797 T8796 arg2Of 38,[
R6838 T8798 T8796 arg3Of ],[
R6839 T8801 T8799 arg1Of study,The
R6840 T8801 T8800 arg1Of study,present
R6841 T8801 T8803 arg1Of study,found
R6842 T8803 T8802 arg1Of found,also
R6843 T8804 T8805 arg1Of Id2,and
R6844 T8805 T8803 arg2Of and,found
R6845 T8805 T8808 arg1Of and,in
R6846 T8805 T8812 arg1Of and,be
R6847 T8805 T8815 arg2Of and,expressed
R6848 T8807 T8805 arg2Of protein,and
R6849 T8807 T8806 arg1Of protein,Id3
R6850 T8810 T8808 arg2Of cells,in
R6851 T8810 T8809 arg1Of cells,B
R6852 T8814 T8813 arg1Of highly,more
R6853 T8815 T8803 arg3Of expressed,found
R6854 T8815 T8811 arg1Of expressed,to
R6855 T8815 T8812 arg2Of expressed,be
R6856 T8815 T8814 arg1Of expressed,highly
R6857 T8815 T8816 arg1Of expressed,than
R6858 T8817 T8816 arg2Of Id1,than
R6859 T8817 T8818 arg1Of Id1,in
R6860 T8821 T8818 arg2Of cells,in
R6861 T8821 T8819 arg1Of cells,resting
R6862 T8821 T8820 arg1Of cells,B
R6863 T8824 T8825 arg1Of BMP-6,did
R6864 T8824 T8827 arg1Of BMP-6,induce
R6865 T8827 T8822 arg1Of induce,However
R6866 T8827 T8823 arg1Of induce,","
R6867 T8827 T8825 arg2Of induce,did
R6868 T8827 T8826 arg1Of induce,not
R6869 T8829 T8827 arg2Of changes,induce
R6870 T8829 T8828 arg1Of changes,significant
R6871 T8829 T8830 arg1Of changes,in
R6872 T8833 T8830 arg2Of expression,in
R6873 T8833 T8831 arg1Of expression,the
R6874 T8833 T8832 arg1Of expression,protein
R6875 T8833 T8834 arg1Of expression,of
R6876 T8835 T8836 arg1Of Id2,and
R6877 T8836 T8834 arg2Of and,of
R6878 T8837 T8836 arg2Of Id3,and
R6879 T8838 T8839 arg1Of It,is
R6880 T8838 T8840 arg2Of It,believed
R6881 T8840 T8839 arg2Of believed,is
R6882 T8843 T8842 arg1Of proteins,Id
R6883 T8843 T8844 arg1Of proteins,block
R6884 T8843 T8847 arg1Of proteins,promote
R6885 T8844 T8846 arg1Of block,and
R6886 T8845 T8844 arg2Of differentiation,block
R6887 T8846 T8840 arg3Of and,believed
R6888 T8846 T8841 arg1Of and,that
R6889 T8846 T8849 arg1Of and,in
R6890 T8847 T8846 arg2Of promote,and
R6891 T8848 T8847 arg2Of proliferation,promote
R6892 T8852 T8849 arg2Of types,in
R6893 T8852 T8850 arg1Of types,various
R6894 T8852 T8851 arg1Of types,cell
R6895 T8852 T8853 arg1Of types,[
R6896 T8854 T8853 arg2Of "39,33",[
R6897 T8855 T8853 arg3Of ],[
R6898 T8857 T8856 arg1Of proteins,Id
R6899 T8857 T8858 arg1Of proteins,act
R6900 T8857 T8868 arg1Of proteins,forming
R6901 T8858 T8859 arg1Of act,as
R6902 T8858 T8867 arg1Of act,by
R6903 T8861 T8860 arg1Of inhibitors,dominant-negative
R6904 T8861 T8862 arg1Of inhibitors,of
R6905 T8861 T8864 arg1Of inhibitors,and
R6906 T8863 T8862 arg2Of E-proteins,of
R6907 T8864 T8859 arg2Of and,as
R6908 T8866 T8864 arg2Of function,and
R6909 T8866 T8865 arg1Of function,Pax5
R6910 T8868 T8867 arg2Of forming,by
R6911 T8868 T8870 arg1Of forming,with
R6912 T8868 T8873 arg1Of forming,","
R6913 T8868 T8874 modOf forming,making
R6914 T8869 T8868 arg2Of dimers,forming
R6915 T8872 T8870 arg2Of proteins,with
R6916 T8872 T8871 arg1Of proteins,these
R6917 T8875 T8874 arg2Of them,making
R6918 T8875 T8876 arg1Of them,unable
R6919 T8875 T8878 arg1Of them,bind
R6920 T8876 T8874 arg3Of unable,making
R6921 T8878 T8876 arg2Of bind,unable
R6922 T8878 T8877 arg1Of bind,to
R6923 T8879 T8878 arg2Of DNA,bind
R6924 T8880 T8881 arg1Of It,has
R6925 T8880 T8882 arg1Of It,been
R6926 T8880 T8883 arg2Of It,proposed
R6927 T8883 T8881 arg2Of proposed,has
R6928 T8883 T8882 arg2Of proposed,been
R6929 T8886 T8885 arg1Of balance,the
R6930 T8886 T8887 arg1Of balance,among
R6931 T8886 T8894 arg1Of balance,might
R6932 T8886 T8895 arg1Of balance,have
R6933 T8888 T8889 arg1Of E-proteins,","
R6934 T8889 T8891 arg1Of ",",and
R6935 T8890 T8889 arg2Of Pax5,","
R6936 T8891 T8887 arg2Of and,among
R6937 T8893 T8891 arg2Of proteins,and
R6938 T8893 T8892 arg1Of proteins,Id
R6939 T8895 T8883 arg3Of have,proposed
R6940 T8895 T8884 arg1Of have,that
R6941 T8895 T8894 arg2Of have,might
R6942 T8895 T8899 arg1Of have,in
R6943 T8898 T8895 arg2Of role,have
R6944 T8898 T8896 arg1Of role,an
R6945 T8898 T8897 arg1Of role,important
R6946 T8902 T8899 arg2Of cells,in
R6947 T8902 T8900 arg2Of cells,activated
R6948 T8902 T8901 arg1Of cells,B
R6949 T8902 T8903 arg1Of cells,[
R6950 T8904 T8903 arg2Of 38,[
R6951 T8905 T8903 arg3Of ],[
R6952 T8908 T8906 arg2Of respect,In
R6953 T8908 T8907 arg1Of respect,that
R6954 T8910 T8911 arg1Of E-proteins,have
R6955 T8910 T8912 arg1Of E-proteins,been
R6956 T8910 T8913 arg2Of E-proteins,implicated
R6957 T8913 T8906 arg1Of implicated,In
R6958 T8913 T8909 arg1Of implicated,","
R6959 T8913 T8911 arg2Of implicated,have
R6960 T8913 T8912 arg2Of implicated,been
R6961 T8913 T8914 arg1Of implicated,in
R6962 T8913 T8925 arg1Of implicated,at
R6963 T8917 T8918 arg1Of promotion,and
R6964 T8918 T8914 arg2Of and,in
R6965 T8918 T8915 arg1Of and,both
R6966 T8918 T8916 arg1Of and,the
R6967 T8918 T8920 arg1Of and,of
R6968 T8919 T8918 arg2Of inhibition,and
R6969 T8922 T8923 arg1Of survival,and
R6970 T8923 T8920 arg2Of and,of
R6971 T8923 T8921 arg1Of and,cell
R6972 T8924 T8923 arg2Of growth,and
R6973 T8927 T8925 arg2Of points,at
R6974 T8927 T8926 arg1Of points,different
R6975 T8927 T8928 arg1Of points,in
R6976 T8930 T8928 arg2Of development,in
R6977 T8930 T8929 arg1Of development,lymphocyte
R6978 T8930 T8931 arg1Of development,[
R6979 T8932 T8931 arg2Of 40,[
R6980 T8933 T8931 arg3Of ],[
R6981 T8937 T8934 arg1Of death,The
R6982 T8937 T8935 arg1Of death,antiproliferative
R6983 T8937 T8936 arg1Of death,and
R6984 T8937 T8938 arg1Of death,inducing
R6985 T8937 T8951 arg1Of death,is
R6986 T8937 T8953 arg1Of death,in
R6987 T8939 T8938 arg2Of effect,inducing
R6988 T8939 T8940 arg1Of effect,of
R6989 T8939 T8942 arg1Of effect,in
R6990 T8939 T8945 arg1Of effect,with
R6991 T8941 T8940 arg2Of BMP-6,of
R6992 T8944 T8942 arg2Of cells,in
R6993 T8944 T8943 arg1Of cells,B
R6994 T8947 T8945 arg2Of upregulation,with
R6995 T8947 T8946 arg1Of upregulation,concomitant
R6996 T8947 T8948 arg1Of upregulation,of
R6997 T8950 T8948 arg2Of protein,of
R6998 T8950 T8949 arg1Of protein,Id1
R6999 T8951 T8952 arg1Of is,therefore
R7000 T8953 T8951 arg2Of in,is
R7001 T8954 T8953 arg2Of line,in
R7002 T8954 T8955 arg1Of line,with
R7003 T8957 T8955 arg2Of view,with
R7004 T8957 T8956 arg1Of view,the
R7005 T8960 T8959 arg1Of proteins,Id
R7006 T8960 T8961 arg1Of proteins,are
R7007 T8960 T8962 arg2Of proteins,required
R7008 T8962 T8957 arg2Of required,view
R7009 T8962 T8958 arg1Of required,that
R7010 T8962 T8961 arg2Of required,are
R7011 T8962 T8963 arg1Of required,for
R7012 T8962 T8976 arg1Of required,[
R7013 T8965 T8963 arg2Of induction,for
R7014 T8965 T8964 arg1Of induction,the
R7015 T8965 T8966 arg1Of induction,of
R7016 T8965 T8971 arg1Of induction,in
R7017 T8965 T8974 arg1Of induction,by
R7018 T8968 T8967 arg1Of arrest,growth
R7019 T8968 T8969 arg1Of arrest,and
R7020 T8969 T8966 arg2Of and,of
R7021 T8970 T8969 arg2Of apoptosis,and
R7022 T8973 T8971 arg2Of progenitors,in
R7023 T8973 T8972 arg1Of progenitors,B-lymphocyte
R7024 T8975 T8974 arg2Of TGF-β,by
R7025 T8977 T8976 arg2Of 40,[
R7026 T8978 T8976 arg3Of ],[
R7027 T8982 T8981 arg1Of proteins,Id
R7028 T8982 T8983 arg1Of proteins,are
R7029 T8982 T8984 arg2Of proteins,known
R7030 T8984 T8979 arg1Of known,Furthermore
R7031 T8984 T8980 arg1Of known,","
R7032 T8984 T8983 arg2Of known,are
R7033 T8984 T8985 arg1Of known,as
R7034 T8987 T8985 arg2Of parts,as
R7035 T8996 T8994 arg2Of cycle,","
R7036 T8996 T8995 arg1Of cycle,cell
R7037 T8997 T8992 arg2Of and,in
R7038 T8998 T8997 arg2Of tumorigenesis,and
R7039 T8998 T8999 arg1Of tumorigenesis,[
R7040 T8987 T8986 arg1Of parts,important
R7041 T8987 T8988 arg1Of parts,of
R7042 T9000 T8999 arg2Of 32,[
R7043 T8990 T8988 arg2Of pathways,of
R7044 T9001 T8999 arg3Of ],[
R7045 T9002 T9003 arg1Of It,is
R7046 T9002 T9005 arg2Of It,established
R7047 T9005 T9003 arg2Of established,is
R7048 T9005 T9004 arg1Of established,well
R7049 T8990 T8989 arg1Of pathways,signalling
R7050 T8990 T8991 arg2Of pathways,involved
R7051 T9008 T9007 arg1Of members,various
R7052 T9008 T9009 arg1Of members,of
R7053 T9008 T9013 arg1Of members,are
R7054 T9008 T9014 arg2Of members,overexpressed
R7055 T8991 T8992 arg1Of involved,in
R7056 T8993 T8994 arg1Of development,","
R7057 T9012 T9009 arg2Of family,of
R7058 T9012 T9010 arg1Of family,the
R7059 T9012 T9011 arg1Of family,Id
R7060 T9014 T9005 arg3Of overexpressed,established
R7061 T9014 T9006 arg1Of overexpressed,that
R7062 T9014 T9013 arg2Of overexpressed,are
R7063 T9014 T9015 arg1Of overexpressed,in
R7064 T9014 T9022 arg1Of overexpressed,generally
R7065 T9015 T9021 arg1Of in,and
R7066 T9017 T9015 arg2Of range,in
R7067 T9017 T9016 arg1Of range,a
R7068 T9017 T9018 arg1Of range,of
R7069 T9020 T9018 arg2Of tumours,of
R7070 T8994 T8997 arg1Of ",",and
R7071 T9020 T9019 arg1Of tumours,human
R7072 T9022 T9021 arg2Of generally,and
R7073 T9024 T9025 arg1Of Id1,appears
R7074 T9024 T9027 arg1Of Id1,be
R7075 T9093 T9091 arg2Of respect,In
R7076 T9025 T9003 modOf appears,is
R7077 T9025 T9023 arg1Of appears,","
R7078 T9027 T9025 arg2Of be,appears
R7079 T9027 T9026 arg1Of be,to
R7080 T9030 T9027 arg2Of member,be
R7081 T9030 T9028 arg1Of member,the
R7082 T9030 T9029 arg1Of member,family
R7083 T9030 T9033 arg2Of member,overexpressed
R7084 T9032 T9031 arg1Of widely,most
R7085 T9093 T9092 arg1Of respect,this
R7086 T9033 T9032 arg1Of overexpressed,widely
R7087 T9033 T9034 arg1Of overexpressed,in
R7088 T9095 T9096 arg1Of it,is
R7089 T9095 T9106 arg1Of it,resulted
R7090 T9098 T9097 arg2Of interest,of
R7091 T9036 T9034 arg2Of variety,in
R7092 T9036 T9035 arg1Of variety,a
R7093 T9036 T9037 arg1Of variety,of
R7094 T9039 T9037 arg2Of malignancies,of
R7095 T9039 T9038 arg1Of malignancies,human
R7096 T9039 T9040 arg1Of malignancies,[
R7097 T9039 T9043 arg1Of malignancies,","
R7098 T9039 T9044 arg1Of malignancies,including
R7099 T9098 T9099 arg1Of interest,that
R7100 T9041 T9040 arg2Of 41,[
R7101 T9042 T9040 arg3Of ],[
R7102 T9098 T9100 arg1Of interest,targeted
R7103 T9101 T9100 arg2Of expression,targeted
R7104 T9046 T9044 arg2Of myeloma,including
R7105 T9046 T9045 arg1Of myeloma,multiple
R7106 T9046 T9047 arg1Of myeloma,[
R7107 T9048 T9047 arg2Of "42,32",[
R7108 T9049 T9047 arg3Of ],[
R7109 T9101 T9102 arg1Of expression,of
R7110 T9053 T9052 arg1Of findings,our
R7111 T9053 T9064 arg1Of findings,might
R7112 T9053 T9065 arg1Of findings,be
R7113 T9053 T9066 arg1Of findings,of
R7114 T9103 T9102 arg2Of Id1,of
R7115 T9055 T9056 arg1Of BMP-6,activates
R7116 T9056 T9053 arg2Of activates,findings
R7117 T9056 T9054 arg1Of activates,that
R7118 T9103 T9104 arg1Of Id1,to
R7119 T9059 T9056 arg2Of pathways,activates
R7120 T9059 T9057 arg1Of pathways,intracellular
R7121 T9059 T9058 arg1Of pathways,signalling
R7122 T9059 T9060 arg1Of pathways,in
R7123 T9105 T9104 arg2Of B-lymphocytes,to
R7124 T9063 T9060 arg2Of cells,in
R7125 T9063 T9061 arg1Of cells,human
R7126 T9063 T9062 arg1Of cells,B
R7127 T9106 T9091 arg1Of resulted,In
R7128 T9065 T9050 arg1Of be,Additionally
R7129 T9065 T9051 arg1Of be,","
R7130 T9065 T9064 arg2Of be,might
R7131 T9065 T9070 arg1Of be,in
R7132 T9066 T9065 arg2Of of,be
R7133 T9106 T9094 arg1Of resulted,","
R7134 T9106 T9096 arg2Of resulted,is
R7135 T9106 T9097 arg1Of resulted,of
R7136 T9106 T9107 arg1Of resulted,in
R7137 T9069 T9066 arg2Of significance,of
R7138 T9069 T9067 arg1Of significance,potential
R7139 T9069 T9068 arg1Of significance,pathophysiological
R7140 T9106 T9123 arg1Of resulted,[
R7141 T9111 T9108 arg1Of development,aberrant
R7142 T9071 T9072 arg1Of lymphoma,and
R7143 T9072 T9070 arg2Of and,in
R7144 T9073 T9072 arg2Of inflammation,and
R7145 T9077 T9074 arg1Of expression,High
R7146 T9077 T9075 arg1Of expression,BMP-6
R7147 T9077 T9076 arg1Of expression,mRNA
R7148 T9077 T9078 arg1Of expression,in
R7149 T9077 T9080 arg1Of expression,has
R7150 T9077 T9081 arg1Of expression,been
R7151 T9077 T9082 arg2Of expression,shown
R7152 T9077 T9084 arg1Of expression,correlate
R7153 T9079 T9078 arg2Of DLBCL,in
R7154 T9111 T9109 arg1Of development,B
R7155 T9111 T9110 arg1Of development,cell
R7156 T9082 T9080 arg2Of shown,has
R7157 T9082 T9081 arg2Of shown,been
R7158 T9084 T9082 arg3Of correlate,shown
R7159 T9084 T9083 arg1Of correlate,to
R7160 T9084 T9085 arg1Of correlate,to
R7161 T9111 T9112 arg1Of development,","
R7162 T9087 T9085 arg2Of outcome,to
R7163 T9087 T9086 arg1Of outcome,unfavourable
R7164 T9087 T9088 arg1Of outcome,[
R7165 T9112 T9116 arg1Of ",",and
R7166 T9089 T9088 arg2Of 12,[
R7167 T9114 T9112 arg2Of apoptosis,","
R7168 T9090 T9088 arg3Of ],[
R7169 T9114 T9113 arg1Of apoptosis,massive
R7170 T9116 T9107 arg2Of and,in
R7171 T9116 T9115 arg1Of and,","
R7172 T9118 T9116 arg2Of development,and
R7173 T9189 T9188 arg1Of cells,B
R7174 T9189 T9190 arg1Of cells,are
R7175 T9189 T9191 arg2Of cells,involved
R7176 T9118 T9117 arg1Of development,subsequent
R7177 T9191 T9187 arg2Of involved,where
R7178 T9191 T9190 arg2Of involved,are
R7179 T9118 T9119 arg1Of development,of
R7180 T9192 T9193 arg1Of It,will
R7181 T9192 T9195 arg1Of It,be
R7182 T9192 T9196 arg1Of It,important
R7183 T9122 T9119 arg2Of lymphomas,of
R7184 T9195 T9193 arg2Of be,will
R7185 T9195 T9194 arg1Of be,therefore
R7186 T9195 T9197 modOf be,to
R7187 T9196 T9195 arg2Of important,be
R7188 T9199 T9197 arg1Of elucidate,to
R7189 T9199 T9198 arg1Of elucidate,further
R7190 T9122 T9120 arg1Of lymphomas,B
R7191 T9201 T9199 arg2Of role,elucidate
R7192 T9201 T9200 arg1Of role,the
R7193 T9201 T9202 arg1Of role,of
R7194 T9201 T9204 arg1Of role,in
R7195 T9201 T9208 arg1Of role,by
R7196 T9122 T9121 arg1Of lymphomas,cell
R7197 T9203 T9202 arg2Of Id-1,of
R7198 T9124 T9123 arg2Of 35,[
R7199 T9207 T9204 arg2Of cells,in
R7200 T9207 T9205 arg1Of cells,human
R7201 T9207 T9206 arg1Of cells,B
R7202 T9125 T9123 arg3Of ],[
R7203 T9209 T9208 arg2Of selective,by
R7204 T9209 T9210 arg1Of selective,over
R7205 T9128 T9129 arg1Of BMP-6,has
R7206 T9211 T9212 arg1Of expression,or
R7207 T9212 T9210 arg2Of or,over
R7208 T9213 T9212 arg2Of inhibition,or
R7209 T9217 T9208 arg3Of expression,by
R7210 T9217 T9214 arg1Of expression,of
R7211 T9217 T9215 arg1Of expression,Id-1
R7212 T9217 T9216 arg1Of expression,gene
R7213 T9128 T9130 arg1Of BMP-6,been
R7214 T9220 T9218 arg2Of role,Given
R7215 T9220 T9219 arg1Of role,the
R7216 T9220 T9221 arg1Of role,of
R7217 T9220 T9223 arg1Of role,in
R7218 T9220 T9228 arg1Of role,demonstrated
R7219 T9128 T9131 arg2Of BMP-6,suggested
R7220 T9222 T9221 arg2Of BMP-6,of
R7221 T9128 T9133 arg1Of BMP-6,play
R7222 T9131 T9129 arg2Of suggested,has
R7223 T9227 T9223 arg2Of cells,in
R7224 T9227 T9224 arg1Of cells,mature
R7225 T9227 T9225 arg1Of cells,human
R7226 T9227 T9226 arg1Of cells,B
R7227 T9228 T9218 modOf demonstrated,Given
R7228 T9229 T9228 arg2Of here,demonstrated
R7229 T9229 T9249 arg2Of here,contribute
R7230 T9131 T9130 arg2Of suggested,been
R7231 T9231 T9232 arg1Of identification,of
R7232 T9231 T9242 arg1Of identification,with
R7233 T9231 T9248 arg1Of identification,might
R7234 T9231 T9249 arg1Of identification,contribute
R7235 T9131 T9142 arg1Of suggested,[
R7236 T9233 T9234 arg1Of BMP-6,producing
R7237 T9131 T9145 arg1Of suggested,and
R7238 T9234 T9237 arg1Of producing,vivo
R7239 T9234 T9238 arg1Of producing,with
R7240 T9235 T9234 arg2Of cells,producing
R7241 T9133 T9131 arg3Of play,suggested
R7242 T9237 T9236 arg1Of vivo,in
R7243 T9133 T9132 arg1Of play,to
R7244 T9239 T9238 arg2Of possibility,with
R7245 T9133 T9136 arg1Of play,in
R7246 T9135 T9133 arg2Of role,play
R7247 T9241 T9232 arg2Of interaction,of
R7248 T9241 T9233 arg1Of interaction,BMP-6
R7249 T9241 T9240 arg1Of interaction,of
R7250 T9243 T9244 arg1Of naïve,and
R7251 T9244 T9242 arg2Of and,with
R7252 T9135 T9134 arg1Of role,a
R7253 T9138 T9136 arg2Of arthritis,in
R7254 T9247 T9244 arg2Of cells,and
R7255 T9247 T9245 arg1Of cells,memory
R7256 T9247 T9246 arg1Of cells,B
R7257 T9249 T9230 arg1Of contribute,","
R7258 T9249 T9248 arg2Of contribute,might
R7259 T9249 T9250 arg1Of contribute,to
R7260 T9138 T9137 arg1Of arthritis,rheumatoid
R7261 T9138 T9139 arg1Of arthritis,(
R7262 T9140 T9139 arg2Of RA,(
R7263 T9252 T9250 arg2Of understanding,to
R7264 T9252 T9251 arg1Of understanding,the
R7265 T9252 T9253 arg1Of understanding,of
R7266 T9141 T9139 arg3Of ),(
R7267 T9257 T9253 arg2Of biology,of
R7268 T9257 T9254 arg1Of biology,mature
R7269 T9257 T9255 arg1Of biology,B
R7270 T9257 T9256 arg1Of biology,cell
R7271 T9143 T9142 arg2Of "43,44",[
R7272 T9261 T9258 arg1Of expression,High
R7273 T9261 T9259 arg1Of expression,BMP-6
R7274 T9261 T9260 arg1Of expression,mRNA
R7275 T9261 T9262 arg1Of expression,in
R7276 T9261 T9264 arg1Of expression,has
R7277 T9261 T9265 arg1Of expression,been
R7278 T9261 T9266 arg2Of expression,detected
R7279 T9144 T9142 arg3Of ],[
R7280 T9263 T9262 arg2Of DLBCL,in
R7281 T9145 T9126 arg1Of and,Moreover
R7282 T9266 T9264 arg2Of detected,has
R7283 T9266 T9265 arg2Of detected,been
R7284 T9266 T9271 arg1Of detected,[
R7285 T9145 T9127 arg1Of and,","
R7286 T9147 T9146 arg1Of levels,elevated
R7287 T9270 T9266 arg1Of profiling,detected
R7288 T9270 T9267 arg2Of profiling,by
R7289 T9270 T9268 arg1Of profiling,gene
R7290 T9270 T9269 arg1Of profiling,expression
R7291 T9272 T9271 arg2Of 12,[
R7292 T9273 T9271 arg3Of ],[
R7293 T9147 T9148 arg1Of levels,of
R7294 T9147 T9152 arg1Of levels,have
R7295 T9276 T9277 arg1Of production,of
R7296 T9276 T9280 arg1Of production,in
R7297 T9276 T9285 arg1Of production,was
R7298 T9276 T9286 arg2Of production,detected
R7299 T9147 T9153 arg1Of levels,been
R7300 T9279 T9277 arg2Of transcripts,of
R7301 T9279 T9278 arg1Of transcripts,BMP-6
R7302 T9147 T9154 arg2Of levels,found
R7303 T9149 T9150 arg1Of Id1,and
R7304 T9284 T9280 arg2Of cells,in
R7305 T9284 T9281 arg1Of cells,normal
R7306 T9284 T9282 arg2Of cells,activated
R7307 T9284 T9283 arg1Of cells,B
R7308 T9150 T9148 arg2Of and,of
R7309 T9151 T9150 arg2Of Id3,and
R7310 T9154 T9145 arg2Of found,and
R7311 T9286 T9274 arg1Of detected,Furthermore
R7312 T9286 T9275 arg1Of detected,","
R7313 T9286 T9285 arg2Of detected,was
R7314 T9286 T9287 arg1Of detected,in
R7315 T9154 T9152 arg2Of found,have
R7316 T9290 T9287 arg2Of study,in
R7317 T9290 T9288 arg1Of study,the
R7318 T9290 T9289 arg1Of study,same
R7319 T9154 T9153 arg2Of found,been
R7320 T9292 T9291 arg2Of note,Of
R7321 T9154 T9155 arg1Of found,in
R7322 T9157 T9155 arg2Of synovia,in
R7323 T9297 T9294 arg1Of loop,an
R7324 T9297 T9295 arg1Of loop,autocrine
R7325 T9297 T9296 arg1Of loop,BMP-6
R7326 T9297 T9298 arg1Of loop,has
R7327 T9297 T9299 arg1Of loop,been
R7328 T9297 T9300 arg2Of loop,reported
R7329 T9157 T9156 arg1Of synovia,the
R7330 T9300 T9291 arg1Of reported,Of
R7331 T9300 T9293 arg1Of reported,","
R7332 T9300 T9298 arg2Of reported,has
R7333 T9300 T9299 arg2Of reported,been
R7334 T9300 T9301 arg1Of reported,by
R7335 T9300 T9306 arg1Of reported,in
R7336 T9300 T9309 arg1Of reported,[
R7337 T9301 T9305 arg1Of by,and
R7338 T9302 T9301 arg2Of others,by
R7339 T9302 T9303 arg1Of others,in
R7340 T9157 T9158 arg1Of synovia,of
R7341 T9304 T9303 arg2Of chondrocytes,in
R7342 T9157 T9160 arg1Of synovia,[
R7343 T9159 T9158 arg2Of RA-patients,of
R7344 T9306 T9305 arg2Of in,and
R7345 T9308 T9306 arg2Of ovarium,in
R7346 T9308 T9307 arg1Of ovarium,the
R7347 T9161 T9160 arg2Of 45,[
R7348 T9310 T9309 arg2Of "46,19,18",[
R7349 T9311 T9309 arg3Of ],[
R7350 T9162 T9160 arg3Of ],[
R7351 T9314 T9315 arg1Of we,wanted
R7352 T9314 T9317 arg1Of we,explore
R7353 T9315 T9312 arg1Of wanted,Therefore
R7354 T9315 T9313 arg1Of wanted,","
R7355 T9166 T9165 arg1Of results,these
R7356 T9317 T9315 arg2Of explore,wanted
R7357 T9317 T9316 arg1Of explore,to
R7358 T9317 T9320 arg1Of explore,for
R7359 T9319 T9317 arg2Of possibility,explore
R7360 T9319 T9318 arg1Of possibility,the
R7361 T9324 T9320 arg2Of loop,for
R7362 T9166 T9167 arg1Of results,point
R7363 T9167 T9163 arg1Of point,Altogether
R7364 T9324 T9321 arg1Of loop,an
R7365 T9324 T9322 arg1Of loop,autocrine
R7366 T9324 T9323 arg1Of loop,BMP-6
R7367 T9324 T9325 arg1Of loop,in
R7368 T9167 T9164 arg1Of point,","
R7369 T9167 T9168 arg1Of point,to
R7370 T9171 T9168 arg2Of role,to
R7371 T9328 T9325 arg2Of cells,in
R7372 T9328 T9326 arg1Of cells,human
R7373 T9328 T9327 arg1Of cells,B
R7374 T9329 T9330 arg1Of We,analysed
R7375 T9330 T9340 arg1Of analysed,by
R7376 T9330 T9364 arg1Of analysed,","
R7377 T9330 T9365 arg1Of analysed,anti-IgM
R7378 T9171 T9169 arg1Of role,an
R7379 T9334 T9330 arg2Of mRNA,analysed
R7380 T9334 T9331 arg1Of mRNA,the
R7381 T9334 T9332 arg1Of mRNA,expression
R7382 T9334 T9333 arg1Of mRNA,BMP-6
R7383 T9334 T9335 arg1Of mRNA,in
R7384 T9171 T9170 arg1Of role,important
R7385 T9171 T9172 arg1Of role,for
R7386 T9171 T9184 arg1Of role,in
R7387 T9339 T9335 arg2Of cells,in
R7388 T9339 T9336 arg1Of cells,peripheral
R7389 T9339 T9337 arg1Of cells,blood
R7390 T9339 T9338 arg1Of cells,B
R7391 T9172 T9183 arg1Of for,and
R7392 T9342 T9341 arg1Of PCR,real-time
R7393 T9342 T9344 arg1Of PCR,and
R7394 T9174 T9172 arg2Of proteins,for
R7395 T9344 T9340 arg2Of and,by
R7396 T9344 T9343 arg1Of and,","
R7397 T9345 T9344 arg2Of report,and
R7398 T9345 T9346 arg1Of report,here
R7399 T9174 T9173 arg1Of proteins,Id
R7400 T9348 T9340 arg3Of upregulation,by
R7401 T9348 T9347 arg1Of upregulation,the
R7402 T9348 T9349 arg1Of upregulation,of
R7403 T9348 T9353 arg1Of upregulation,after
R7404 T9348 T9355 arg1Of upregulation,with
R7405 T9174 T9175 arg1Of proteins,in
R7406 T9177 T9175 arg2Of regulation,in
R7407 T9352 T9349 arg2Of transcripts,of
R7408 T9352 T9350 arg1Of transcripts,endogenous
R7409 T9352 T9351 arg1Of transcripts,BMP-6
R7410 T9354 T9353 arg2Of stimulation,after
R7411 T9356 T9357 arg1Of FCS,","
R7412 T9357 T9355 arg2Of ",",with
R7413 T9357 T9360 arg1Of ",",and
R7414 T9357 T9361 arg1Of ",",","
R7415 T9357 T9363 arg1Of ",",importantly
R7416 T9359 T9357 arg2Of AB-serum,","
R7417 T9359 T9358 arg1Of AB-serum,human
R7418 T9177 T9176 arg1Of regulation,the
R7419 T9177 T9178 arg1Of regulation,of
R7420 T9182 T9178 arg2Of homeostasis,of
R7421 T9363 T9362 arg1Of importantly,most
R7422 T9369 T9368 arg1Of attempts,our
R7423 T9369 T9370 modOf attempts,to
R7424 T9369 T9375 arg1Of attempts,were
R7425 T9369 T9376 arg1Of attempts,unsuccessful
R7426 T9182 T9179 arg1Of homeostasis,normal
R7427 T9371 T9370 arg1Of study,to
R7428 T9182 T9180 arg1Of homeostasis,B
R7429 T9182 T9181 arg1Of homeostasis,cell
R7430 T9184 T9183 arg2Of in,and
R7431 T9374 T9371 arg2Of levels,study
R7432 T9374 T9372 arg1Of levels,BMP-6
R7433 T9374 T9373 arg1Of levels,protein
R7434 T9375 T9366 arg1Of were,However
R7435 T9375 T9367 arg1Of were,","
R7436 T9376 T9375 arg2Of unsuccessful,were
R7437 T9376 T9378 arg1Of unsuccessful,to
R7438 T9378 T9377 arg1Of to,due
R7439 T9379 T9378 arg2Of problems,to
R7440 T9379 T9380 arg1Of problems,with
R7441 T9185 T9184 arg2Of diseases,in
R7442 T9185 T9186 arg1Of diseases,","
R7443 T9382 T9381 arg1Of binding,unspecific
R7444 T9382 T9383 arg1Of binding,of
R7445 T9382 T9389 arg1Of binding,and
R7446 T9185 T9187 arg1Of diseases,where
R7447 T9481 T9466 arg1Of suggested,In
R7448 T9481 T9469 arg1Of suggested,","
R7449 T9481 T9480 arg2Of suggested,was
R7450 T9386 T9383 arg2Of antibodies,of
R7451 T9386 T9384 arg1Of antibodies,the
R7452 T9386 T9385 arg1Of antibodies,anti-BMP-6
R7453 T9386 T9387 arg2Of antibodies,tested
R7454 T9483 T9482 arg1Of upregulation,The
R7455 T9389 T9380 arg2Of and,with
R7456 T9389 T9388 arg1Of and,","
R7457 T9390 T9389 arg2Of lack,and
R7458 T9390 T9391 arg1Of lack,of
R7459 T9393 T9391 arg2Of staining,of
R7460 T9393 T9392 arg1Of staining,specific
R7461 T9393 T9394 arg1Of staining,in
R7462 T9483 T9484 arg1Of upregulation,of
R7463 T9396 T9394 arg2Of cells,in
R7464 T9396 T9395 arg1Of cells,control
R7465 T9396 T9397 arg2Of cells,known
R7466 T9483 T9487 arg1Of upregulation,after
R7467 T9396 T9399 arg1Of cells,express
R7468 T9483 T9489 arg1Of upregulation,is
R7469 T9483 T9490 arg1Of upregulation,of
R7470 T9486 T9484 arg2Of BMP-6-transcripts,of
R7471 T9399 T9397 arg3Of express,known
R7472 T9399 T9398 arg1Of express,to
R7473 T9401 T9399 arg2Of mRNA,express
R7474 T9401 T9400 arg1Of mRNA,BMP-6
R7475 T9486 T9485 arg1Of BMP-6-transcripts,the
R7476 T9403 T9402 arg2Of contrast,In
R7477 T9488 T9487 arg2Of IgM-crosslinking,after
R7478 T9489 T9493 arg1Of is,[
R7479 T9407 T9405 arg1Of protein,the
R7480 T9407 T9406 arg1Of protein,recombinant
R7481 T9407 T9408 arg1Of protein,was
R7482 T9407 T9410 arg2Of protein,detected
R7483 T9410 T9402 arg1Of detected,In
R7484 T9410 T9404 arg1Of detected,","
R7485 T9410 T9408 arg2Of detected,was
R7486 T9410 T9409 arg1Of detected,readily
R7487 T9490 T9489 arg2Of of,is
R7488 T9413 T9411 arg2Of respect,In
R7489 T9413 T9412 arg1Of respect,that
R7490 T9492 T9490 arg2Of interest,of
R7491 T9416 T9415 arg1Of investigators,few
R7492 T9416 T9417 arg1Of investigators,have
R7493 T9416 T9418 arg1Of investigators,detected
R7494 T9418 T9411 arg1Of detected,In
R7495 T9418 T9414 arg1Of detected,","
R7496 T9418 T9417 arg2Of detected,have
R7497 T9492 T9491 arg1Of interest,pathophysiologic
R7498 T9420 T9418 arg2Of protein,detected
R7499 T9420 T9419 arg1Of protein,BMP-6
R7500 T9420 T9421 arg1Of protein,in
R7501 T9494 T9493 arg2Of 12,[
R7502 T9420 T9425 arg1Of protein,in
R7503 T9495 T9493 arg3Of ],[
R7504 T9421 T9423 arg1Of in,","
R7505 T9422 T9421 arg2Of humans,in
R7506 T9497 T9496 arg1Of loss,A
R7507 T9425 T9423 arg2Of in,","
R7508 T9425 T9424 arg1Of in,especially
R7509 T9427 T9425 arg2Of tissue,in
R7510 T9427 T9426 arg1Of tissue,non-pathogenic
R7511 T9429 T9428 arg1Of possibility,The
R7512 T9429 T9430 arg1Of possibility,of
R7513 T9429 T9436 arg1Of possibility,is
R7514 T9429 T9437 arg1Of possibility,in
R7515 T9497 T9498 arg1Of loss,of
R7516 T9432 T9430 arg2Of production,of
R7517 T9432 T9431 arg1Of production,BMP-6
R7518 T9432 T9433 arg1Of production,in
R7519 T9497 T9500 arg1Of loss,has
R7520 T9497 T9501 arg1Of loss,been
R7521 T9435 T9433 arg2Of B-cells,in
R7522 T9497 T9502 arg2Of loss,suggested
R7523 T9435 T9434 arg1Of B-cells,human
R7524 T9497 T9504 arg1Of loss,be
R7525 T9437 T9436 arg2Of in,is
R7526 T9438 T9437 arg2Of line,in
R7527 T9438 T9439 arg1Of line,with
R7528 T9499 T9498 arg2Of TGF-β-responsiveness,of
R7529 T9442 T9439 arg2Of work,with
R7530 T9442 T9440 arg1Of work,a
R7531 T9442 T9441 arg1Of work,recent
R7532 T9442 T9443 arg1Of work,that
R7533 T9442 T9444 arg1Of work,reported
R7534 T9502 T9500 arg2Of suggested,has
R7535 T9444 T9453 arg1Of reported,","
R7536 T9444 T9454 modOf reported,infiltrating
R7537 T9446 T9444 arg2Of production,reported
R7538 T9446 T9445 arg1Of production,the
R7539 T9446 T9447 arg1Of production,of
R7540 T9446 T9449 arg1Of production,in
R7541 T9448 T9447 arg2Of BMP-6,of
R7542 T9502 T9501 arg2Of suggested,been
R7543 T9502 T9511 arg1Of suggested,[
R7544 T9452 T9449 arg2Of cells,in
R7545 T9452 T9450 arg1Of cells,mouse
R7546 T9452 T9451 arg1Of cells,B
R7547 T9502 T9514 arg1Of suggested,and
R7548 T9504 T9502 arg3Of be,suggested
R7549 T9457 T9454 arg2Of marrow,infiltrating
R7550 T9457 T9455 arg1Of marrow,the
R7551 T9457 T9456 arg1Of marrow,bone
R7552 T9457 T9458 arg1Of marrow,of
R7553 T9504 T9503 arg1Of be,to
R7554 T9459 T9458 arg2Of mice,of
R7555 T9459 T9460 arg1Of mice,with
R7556 T9507 T9504 arg2Of contribution,be
R7557 T9462 T9460 arg2Of arthritis,with
R7558 T9462 T9461 arg1Of arthritis,inflammatory
R7559 T9462 T9463 arg1Of arthritis,[
R7560 T9464 T9463 arg2Of 43,[
R7561 T9465 T9463 arg3Of ],[
R7562 T9468 T9466 arg2Of study,In
R7563 T9468 T9467 arg1Of study,this
R7564 T9507 T9505 arg1Of contribution,a
R7565 T9507 T9506 arg1Of contribution,critical
R7566 T9471 T9470 arg1Of role,a
R7567 T9507 T9508 arg1Of contribution,to
R7568 T9510 T9508 arg2Of transformation,to
R7569 T9471 T9472 arg1Of role,for
R7570 T9471 T9480 arg1Of role,was
R7571 T9471 T9481 arg2Of role,suggested
R7572 T9510 T9509 arg1Of transformation,malignant
R7573 T9473 T9472 arg2Of BMPs,for
R7574 T9512 T9511 arg2Of "47,48",[
R7575 T9473 T9474 arg1Of BMPs,in
R7576 T9513 T9511 arg3Of ],[
R7577 T9477 T9474 arg2Of process,in
R7578 T9477 T9475 arg1Of process,the
R7579 T9477 T9476 arg1Of process,inflammatoric
R7580 T9477 T9478 arg1Of process,of
R7581 T9479 T9478 arg2Of arthritis,of
R7582 T9517 T9515 arg1Of mechanisms,similar
R7583 T9517 T9516 arg1Of mechanisms,oncogenic
R7584 T9517 T9518 arg1Of mechanisms,have
R7585 T9517 T9519 arg1Of mechanisms,been
R7586 T9577 T9576 arg1Of context,cellular
R7587 T9577 T9578 arg1Of context,of
R7588 T9577 T9583 arg1Of context,might
R7589 T9577 T9584 arg1Of context,define
R7590 T9517 T9520 arg2Of mechanisms,postulated
R7591 T9520 T9514 arg2Of postulated,and
R7592 T9582 T9578 arg2Of cell,of
R7593 T9582 T9579 arg1Of cell,the
R7594 T9582 T9580 arg1Of cell,BMP
R7595 T9582 T9581 arg1Of cell,target
R7596 T9584 T9574 arg2Of define,indicating
R7597 T9584 T9575 arg1Of define,that
R7598 T9584 T9583 arg2Of define,might
R7599 T9520 T9518 arg2Of postulated,have
R7600 T9520 T9519 arg2Of postulated,been
R7601 T9520 T9521 arg1Of postulated,for
R7602 T9588 T9584 arg2Of effects,define
R7603 T9588 T9585 arg1Of effects,the
R7604 T9588 T9586 arg1Of effects,various
R7605 T9588 T9587 arg2Of effects,observed
R7606 T9589 T9591 arg1Of In,to
R7607 T9590 T9589 arg2Of contrast,In
R7608 T9522 T9521 arg2Of BMPs,for
R7609 T9593 T9589 arg3Of upregulation,In
R7610 T9593 T9592 arg1Of upregulation,the
R7611 T9593 T9594 arg1Of upregulation,of
R7612 T9596 T9594 arg2Of transcript,of
R7613 T9596 T9595 arg1Of transcript,BMP-6
R7614 T9596 T9597 arg1Of transcript,in
R7615 T9523 T9524 arg1Of Lines,of
R7616 T9599 T9597 arg2Of cells,in
R7617 T9599 T9598 arg1Of cells,B
R7618 T9523 T9526 arg1Of Lines,suggest
R7619 T9525 T9524 arg2Of evidence,of
R7620 T9601 T9602 arg1Of we,were
R7621 T9601 T9604 arg1Of we,able
R7622 T9601 T9606 arg1Of we,detect
R7623 T9526 T9527 arg1Of suggest,[
R7624 T9601 T9632 arg1Of we,consistent
R7625 T9602 T9589 arg1Of were,In
R7626 T9526 T9530 arg1Of suggest,that
R7627 T9602 T9600 arg1Of were,","
R7628 T9602 T9603 arg1Of were,not
R7629 T9602 T9631 arg1Of were,","
R7630 T9602 T9632 modOf were,consistent
R7631 T9602 T9648 arg1Of were,[
R7632 T9604 T9602 arg2Of able,were
R7633 T9528 T9527 arg2Of 49,[
R7634 T9606 T9604 arg2Of detect,able
R7635 T9606 T9605 arg1Of detect,to
R7636 T9608 T9606 arg2Of transcripts,detect
R7637 T9608 T9607 arg1Of transcripts,BMP-6
R7638 T9608 T9609 arg1Of transcripts,in
R7639 T9529 T9527 arg3Of ],[
R7640 T9533 T9531 arg2Of stages,at
R7641 T9613 T9614 arg1Of CD4+,or
R7642 T9615 T9614 arg2Of CD8+,or
R7643 T9617 T9609 arg2Of cells,in
R7644 T9617 T9610 arg1Of cells,human
R7645 T9617 T9611 arg1Of cells,peripheral
R7646 T9617 T9612 arg1Of cells,blood
R7647 T9617 T9613 arg1Of cells,CD4+
R7648 T9617 T9615 arg1Of cells,CD8+
R7649 T9617 T9616 arg1Of cells,T
R7650 T9617 T9618 arg1Of cells,(
R7651 T9619 T9620 arg1Of resting,or
R7652 T9533 T9532 arg1Of stages,early
R7653 T9533 T9534 arg1Of stages,of
R7654 T9621 T9620 arg2Of stimulated,or
R7655 T9621 T9622 arg1Of stimulated,with
R7656 T9621 T9626 arg1Of stimulated,;
R7657 T9623 T9624 arg1Of anti-CD3,and
R7658 T9624 T9622 arg2Of and,with
R7659 T9625 T9624 arg2Of anti-CD28,and
R7660 T9535 T9534 arg2Of carcinogenesis,of
R7661 T9627 T9618 arg2Of data,(
R7662 T9627 T9619 arg1Of data,resting
R7663 T9627 T9621 arg2Of data,stimulated
R7664 T9627 T9629 arg2Of data,shown
R7665 T9629 T9628 arg1Of shown,not
R7666 T9630 T9618 arg3Of ),(
R7667 T9537 T9538 arg1Of BMP-6,is
R7668 T9632 T9633 arg1Of consistent,with
R7669 T9537 T9545 arg1Of BMP-6,suppresses
R7670 T9635 T9633 arg2Of findings,with
R7671 T9635 T9634 arg1Of findings,the
R7672 T9635 T9636 arg1Of findings,in
R7673 T9635 T9646 arg1Of findings,in
R7674 T9538 T9539 arg1Of is,not
R7675 T9639 T9637 arg1Of lines,T
R7676 T9639 T9638 arg1Of lines,cell
R7677 T9639 T9640 arg1Of lines,[
R7678 T9639 T9643 arg1Of lines,and
R7679 T9538 T9544 arg1Of is,but
R7680 T9641 T9640 arg2Of 20,[
R7681 T9642 T9640 arg3Of ],[
R7682 T9542 T9538 arg2Of promoter,is
R7683 T9643 T9636 arg2Of and,in
R7684 T9645 T9643 arg2Of cells,and
R7685 T9645 T9644 arg1Of cells,T
R7686 T9647 T9646 arg2Of mice,in
R7687 T9649 T9648 arg2Of 43,[
R7688 T9542 T9540 arg1Of promoter,a
R7689 T9650 T9648 arg3Of ],[
R7690 T9542 T9541 arg1Of promoter,tumour
R7691 T9544 T9526 arg2Of but,suggest
R7692 T9654 T9651 arg1Of sources,Other
R7693 T9654 T9652 arg1Of sources,potential
R7694 T9654 T9653 arg1Of sources,BMP-6
R7695 T9654 T9655 arg1Of sources,for
R7696 T9654 T9661 arg1Of sources,might
R7697 T9654 T9662 arg1Of sources,be
R7698 T9544 T9531 arg1Of but,at
R7699 T9658 T9655 arg2Of cells,for
R7700 T9658 T9656 arg1Of cells,mature
R7701 T9658 T9657 arg1Of cells,B
R7702 T9658 T9660 arg1Of cells,vivo
R7703 T9544 T9536 arg1Of but,","
R7704 T9660 T9659 arg1Of vivo,in
R7705 T9544 T9543 arg1Of but,","
R7706 T9662 T9661 arg2Of be,might
R7707 T9662 T9671 arg1Of be,with
R7708 T9664 T9662 arg2Of cells,be
R7709 T9664 T9663 arg1Of cells,other
R7710 T9664 T9665 arg1Of cells,of
R7711 T9545 T9544 arg2Of suppresses,but
R7712 T9668 T9669 arg1Of system,or
R7713 T9669 T9665 arg2Of or,of
R7714 T9669 T9666 arg1Of or,the
R7715 T9669 T9667 arg1Of or,immune
R7716 T9546 T9547 arg1Of benign,and
R7717 T9670 T9669 arg2Of tissue,or
R7718 T9671 T9673 arg1Of with,to
R7719 T9672 T9671 arg2Of contact,with
R7720 T9548 T9547 arg2Of malignant,and
R7721 T9550 T9545 arg2Of outgrowth,suppresses
R7722 T9550 T9546 arg1Of outgrowth,benign
R7723 T9550 T9548 arg1Of outgrowth,malignant
R7724 T9550 T9549 arg1Of outgrowth,tumour
R7725 T9552 T9551 arg1Of findings,These
R7726 T9676 T9671 arg3Of system,with
R7727 T9676 T9674 arg1Of system,the
R7728 T9676 T9675 arg1Of system,hematopoietic
R7729 T9679 T9678 arg1Of recognized,well
R7730 T9680 T9677 arg1Of source,One
R7731 T9680 T9679 arg1Of source,recognized
R7732 T9680 T9681 arg1Of source,for
R7733 T9680 T9684 arg1Of source,is
R7734 T9552 T9553 arg1Of findings,are
R7735 T9552 T9554 arg1Of findings,in
R7736 T9683 T9681 arg2Of production,for
R7737 T9683 T9682 arg1Of production,BMP-6
R7738 T9553 T9573 arg1Of are,","
R7739 T9553 T9574 modOf are,indicating
R7740 T9684 T9692 arg1Of is,[
R7741 T9554 T9553 arg2Of in,are
R7742 T9556 T9554 arg2Of agreement,in
R7743 T9687 T9686 arg1Of bone,human
R7744 T9687 T9688 arg1Of bone,and
R7745 T9688 T9684 arg2Of and,is
R7746 T9688 T9685 arg1Of and,the
R7747 T9556 T9555 arg1Of agreement,good
R7748 T9691 T9688 arg2Of stroma,and
R7749 T9691 T9689 arg1Of stroma,bone
R7750 T9691 T9690 arg1Of stroma,marrow
R7751 T9556 T9557 arg1Of agreement,with
R7752 T9693 T9692 arg2Of "51,8",[
R7753 T9559 T9557 arg2Of findings,with
R7754 T9694 T9692 arg3Of ],[
R7755 T9559 T9558 arg1Of findings,previous
R7756 T9559 T9560 arg1Of findings,for
R7757 T9698 T9717 arg1Of is,and
R7758 T9699 T9698 arg2Of noteworthy,is
R7759 T9564 T9560 arg2Of members,for
R7760 T9705 T9701 arg1Of cells,human
R7761 T9705 T9702 arg1Of cells,umbilical
R7762 T9705 T9703 arg1Of cells,vein
R7763 T9705 T9704 arg1Of cells,endothelial
R7764 T9705 T9706 arg1Of cells,(
R7765 T9705 T9710 arg1Of cells,express
R7766 T9707 T9706 arg2Of HUVEC,(
R7767 T9708 T9706 arg3Of ),(
R7768 T9710 T9697 arg1Of express,it
R7769 T9710 T9698 arg1Of express,is
R7770 T9710 T9699 arg1Of express,noteworthy
R7771 T9710 T9700 arg1Of express,that
R7772 T9710 T9709 arg1Of express,highly
R7773 T9564 T9561 arg1Of members,other
R7774 T9712 T9710 arg2Of mRNA,express
R7775 T9564 T9562 arg1Of members,TGF-β
R7776 T9712 T9711 arg1Of mRNA,BMP-6
R7777 T9712 T9713 arg1Of mRNA,[
R7778 T9714 T9713 arg2Of 52,[
R7779 T9564 T9563 arg1Of members,family
R7780 T9715 T9713 arg3Of ],[
R7781 T9564 T9565 arg1Of members,","
R7782 T9564 T9566 arg1Of members,including
R7783 T9717 T9695 arg1Of and,Furthermore
R7784 T9717 T9696 arg1Of and,","
R7785 T9717 T9716 arg1Of and,","
R7786 T9567 T9568 arg1Of TGF-β1,and
R7787 T9719 T9718 arg1Of endothelium,vascular
R7788 T9719 T9720 arg1Of endothelium,has
R7789 T9719 T9721 arg1Of endothelium,been
R7790 T9719 T9722 arg2Of endothelium,reported
R7791 T9719 T9724 arg1Of endothelium,produce
R7792 T9722 T9717 arg2Of reported,and
R7793 T9722 T9720 arg2Of reported,has
R7794 T9722 T9721 arg2Of reported,been
R7795 T9724 T9722 arg3Of produce,reported
R7796 T9724 T9723 arg1Of produce,to
R7797 T9724 T9726 arg1Of produce,[
R7798 T9725 T9724 arg2Of BMP-6,produce
R7799 T9568 T9566 arg2Of and,including
R7800 T9727 T9726 arg2Of 53,[
R7801 T9568 T9570 arg1Of and,[
R7802 T9728 T9726 arg3Of ],[
R7803 T9569 T9568 arg2Of BMP-4,and
R7804 T9730 T9729 arg1Of studies,These
R7805 T9730 T9731 arg1Of studies,might
R7806 T9730 T9732 arg1Of studies,imply
R7807 T9732 T9731 arg2Of imply,might
R7808 T9734 T9732 arg2Of role,imply
R7809 T9734 T9733 arg1Of role,a
R7810 T9734 T9735 arg1Of role,for
R7811 T9734 T9737 arg1Of role,in
R7812 T9571 T9570 arg2Of 50,[
R7813 T9736 T9735 arg2Of BMP-6,for
R7814 T9739 T9737 arg2Of migration,in
R7815 T9739 T9738 arg1Of migration,transendothelial
R7816 T9739 T9740 arg1Of migration,of
R7817 T9572 T9570 arg3Of ],[
R7818 T9772 T9773 arg1Of neutrophil,and
R7819 T9742 T9740 arg2Of cells,of
R7820 T9742 T9741 arg1Of cells,B
R7821 T9744 T9743 arg1Of mRNA,BMP-6
R7822 T9744 T9745 arg1Of mRNA,has
R7823 T9744 T9746 arg1Of mRNA,been
R7824 T9744 T9747 arg2Of mRNA,demonstrated
R7825 T9747 T9745 arg2Of demonstrated,has
R7826 T9747 T9746 arg2Of demonstrated,been
R7827 T9747 T9748 arg1Of demonstrated,in
R7828 T9747 T9756 arg1Of demonstrated,in
R7829 T9748 T9754 arg1Of in,but
R7830 T9752 T9748 arg2Of lines,in
R7831 T9752 T9749 arg1Of lines,murine
R7832 T9752 T9750 arg1Of lines,macrophage
R7833 T9752 T9751 arg1Of lines,cell
R7834 T9754 T9753 arg1Of but,","
R7835 T9773 T9771 arg2Of and,of
R7836 T9756 T9754 arg2Of in,but
R7837 T9756 T9755 arg1Of in,not
R7838 T9775 T9773 arg2Of origin,and
R7839 T9757 T9756 arg2Of humans,in
R7840 T9757 T9758 arg1Of humans,[
R7841 T9775 T9774 arg1Of origin,monocytic
R7842 T9778 T9761 arg1Of described,In
R7843 T9759 T9758 arg2Of 54,[
R7844 T9760 T9758 arg3Of ],[
R7845 T9761 T9763 arg1Of In,with
R7846 T9762 T9761 arg2Of accordance,In
R7847 T9778 T9766 arg1Of described,","
R7848 T9778 T9776 arg2Of described,have
R7849 T9765 T9761 arg3Of findings,In
R7850 T9778 T9777 arg2Of described,been
R7851 T9765 T9764 arg1Of findings,these
R7852 T9780 T9778 arg3Of be,described
R7853 T9780 T9779 arg1Of be,to
R7854 T9770 T9767 arg1Of lines,other
R7855 T9770 T9768 arg1Of lines,human
R7856 T9770 T9769 arg1Of lines,cell
R7857 T9770 T9771 arg1Of lines,of
R7858 T9770 T9776 arg1Of lines,have
R7859 T9770 T9777 arg1Of lines,been
R7860 T9770 T9778 arg2Of lines,described
R7861 T9770 T9780 arg1Of lines,be
R7862 T9770 T9781 arg1Of lines,negative
R7863 T9780 T9786 arg1Of be,[
R7864 T9781 T9780 arg2Of negative,be
R7865 T9781 T9782 arg1Of negative,for
R7866 T9785 T9782 arg2Of transcript,for
R7867 T9785 T9783 arg1Of transcript,the
R7868 T9785 T9784 arg1Of transcript,BMP-6
R7869 T9787 T9786 arg2Of 20,[
R7872 T9788 T9786 arg3Of ],[
R7873 T9791 T9789 arg2Of knowledge,To
R7878 T9791 T9790 arg1Of knowledge,our
R7880 T9793 T9794 arg1Of there,is
R7882 T9794 T9789 arg1Of is,To
R7885 T9794 T9792 arg1Of is,","
R7887 T9794 T9795 arg1Of is,currently
R7888 T9797 T9794 arg2Of report,is
R7891 T9797 T9796 arg1Of report,no
R7892 T9797 T9798 arg1Of report,about
R7893 T9800 T9798 arg2Of production,about
R7894 T9800 T9799 arg1Of production,BMP-6
R7895 T9800 T9801 arg1Of production,of
R7896 T9804 T9801 arg2Of cells,of
R7897 T9804 T9802 arg1Of cells,human
R7898 T9804 T9803 arg1Of cells,dendritic

bionlp-st-ge-2016-coref

Id Subject Object Predicate Lexical cue
T9812 2215-2239 Antecedent denotes the BMP type I receptors
T9813 2265-2286 Antecedent denotes the type II-receptors
T9814 2339-2351 Anaphor denotes several BMPs
T9815 2363-2368 Antecedent denotes BMP-6
T9816 4281-4284 Anaphor denotes its
T9817 4177-4180 Antecedent denotes Id1
T9818 4815-4830 Anaphor denotes the Id proteins
T9819 4782-4785 Antecedent denotes Id2
T9820 4790-4793 Antecedent denotes Id3
T9821 5295-5309 Anaphor denotes these proteins
T9822 5258-5262 Antecedent denotes Pax5
T9823 5318-5322 Anaphor denotes them
T9824 6189-6206 Anaphor denotes the family member
T9825 6171-6174 Antecedent denotes Id1
T9805 2215-2239 Anaphor denotes the BMP type I receptors
T9806 2240-2247 Antecedent denotes Act-RIA
T9807 2252-2259 Antecedent denotes BMP-RIB
T9808 2265-2286 Anaphor denotes the type II-receptors
T9809 2287-2294 Antecedent denotes BMP-RII
T9810 2299-2307 Antecedent denotes Act-RIIb
T9811 2309-2314 Anaphor denotes which
R7879 T9814 T9815 boundBy several BMPs,BMP-6
R7881 T9816 T9817 boundBy its,Id1
R7883 T9818 T9819 boundBy the Id proteins,Id2
R7884 T9818 T9820 boundBy the Id proteins,Id3
R7886 T9821 T9822 boundBy these proteins,Pax5
R7889 T9823 T9822 boundBy them,Pax5
R7890 T9824 T9825 boundBy the family member,Id1
R7870 T9805 T9806 boundBy the BMP type I receptors,Act-RIA
R7871 T9805 T9807 boundBy the BMP type I receptors,BMP-RIB
R7874 T9808 T9809 boundBy the type II-receptors,BMP-RII
R7875 T9808 T9810 boundBy the type II-receptors,Act-RIIb
R7876 T9811 T9805 boundBy which,the BMP type I receptors
R7877 T9811 T9808 boundBy which,the type II-receptors

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T10324 11-17 JJ denotes Recent
T10325 18-25 NNS denotes studies
T10326 26-30 VBP denotes have
T10327 31-43 VBN denotes demonstrated
T10328 44-46 DT denotes an
T10329 47-56 JJ denotes important
T10330 57-61 NN denotes role
T10331 62-65 IN denotes for
T10332 66-69 NN denotes BMP
T10333 70-81 RB denotes superfamily
T10334 82-89 NNS denotes members
T10335 90-92 IN denotes in
T10336 93-106 JJ denotes hematopoietic
T10337 107-111 NN denotes stem
T10338 112-117 NNS denotes cells
T10339 117-118 , denotes ,
T10340 119-124 JJ denotes early
T10341 125-135 NNS denotes thymocytes
T10342 136-137 NNP denotes [
T10343 137-140 CD denotes 6,7
T10344 140-141 NNP denotes ]
T10345 142-145 CC denotes and
T10346 146-152 NNP denotes B-cell
T10347 153-165 NNS denotes malignancies
T10348 166-167 NNP denotes [
T10349 167-174 CD denotes 8,11,12
T10350 174-175 NNP denotes ]
T10351 175-176 , denotes ,
T10352 177-180 CC denotes but
T10353 181-182 DT denotes a
T10354 183-187 NN denotes role
T10355 188-191 IN denotes for
T10356 192-196 NNS denotes BMPs
T10357 197-199 IN denotes in
T10358 200-206 JJ denotes normal
T10359 207-212 JJ denotes human
T10360 213-214 NNP denotes B
T10361 215-220 NNS denotes cells
T10362 221-224 VBZ denotes has
T10363 225-235 RB denotes previously
T10364 236-239 RB denotes not
T10365 240-244 VBN denotes been
T10366 245-253 VBN denotes reported
T10367 253-254 . denotes .
T10368 255-258 DT denotes The
T10369 259-266 JJ denotes present
T10370 267-272 NN denotes study
T10371 273-285 VBD denotes demonstrated
T10372 286-287 DT denotes a
T10373 288-299 JJ denotes significant
T10374 300-317 JJ denotes antiproliferative
T10375 318-324 NN denotes effect
T10376 325-327 IN denotes of
T10377 328-333 NN denotes BMP-6
T10378 334-336 IN denotes in
T10379 337-347 JJ denotes peripheral
T10380 348-353 NN denotes blood
T10381 354-358 NNP denotes CD19
T10382 358-359 NNP denotes +
T10383 360-361 NNP denotes B
T10384 362-367 NNS denotes cells
T10385 367-368 . denotes .
T10386 369-381 RB denotes Additionally
T10387 381-382 , denotes ,
T10388 383-388 NNP denotes BMP-6
T10389 389-396 VBD denotes induced
T10390 397-401 NN denotes cell
T10391 402-407 NN denotes death
T10392 408-410 IN denotes in
T10393 411-415 NNP denotes CD27
T10394 415-416 NNP denotes +
T10395 417-423 NN denotes memory
T10396 424-425 NNP denotes B
T10397 426-431 NNS denotes cells
T10398 432-434 RB denotes as
T10399 435-439 RB denotes well
T10400 440-442 IN denotes as
T10401 443-445 IN denotes in
T10402 446-447 DT denotes a
T10403 448-455 NNP denotes Burkitt
T10404 456-464 NN denotes lymphoma
T10405 465-469 NN denotes cell
T10406 470-474 NN denotes line
T10407 475-476 -LRB- denotes (
T10408 476-481 NNP denotes Ramos
T10409 481-482 -RRB- denotes )
T10410 482-483 . denotes .
T10411 484-495 RB denotes Importantly
T10412 495-496 , denotes ,
T10413 497-502 NNP denotes BMP-6
T10414 503-510 VBD denotes induced
T10415 511-512 DT denotes a
T10416 513-518 JJ denotes rapid
T10417 519-522 CC denotes and
T10418 523-529 JJ denotes marked
T10419 530-538 NN denotes increase
T10420 539-541 IN denotes in
T10421 542-548 NNP denotes Smad-1
T10422 548-549 CD denotes /
T10423 549-552 CD denotes 5/8
T10424 553-568 NN denotes phosphorylation
T10425 568-569 . denotes .
T10426 570-581 RB denotes Furthermore
T10427 581-582 , denotes ,
T10428 583-586 DT denotes the
T10429 587-592 NNP denotes BMP-6
T10430 593-600 VBD denotes induced
T10431 601-605 NNP denotes Smad
T10432 606-621 NN denotes phosphorylation
T10433 622-625 VBD denotes was
T10434 626-634 VBN denotes followed
T10435 635-637 IN denotes by
T10436 638-639 DT denotes a
T10437 640-649 JJ denotes selective
T10438 650-662 NN denotes upregulation
T10439 663-665 IN denotes of
T10440 666-669 NNP denotes Id1
T10441 670-674 NNP denotes mRNA
T10442 675-678 CC denotes and
T10443 679-689 JJ denotes subsequent
T10444 690-693 JJ denotes Id1
T10445 694-701 NN denotes protein
T10446 701-702 . denotes .
T10447 703-705 IN denotes In
T10448 706-709 DT denotes the
T10449 710-717 JJ denotes present
T10450 718-723 NN denotes study
T10451 723-724 , denotes ,
T10452 725-728 DT denotes the
T10453 729-741 VBN denotes demonstrated
T10454 742-759 JJ denotes antiproliferative
T10455 760-766 NN denotes effect
T10456 767-769 IN denotes of
T10457 770-775 NN denotes BMP-6
T10458 776-778 IN denotes in
T10459 779-787 JJ denotes anti-IgM
T10460 788-795 VBN denotes treated
T10461 796-797 NNP denotes B
T10462 798-803 NNS denotes cells
T10463 804-807 VBD denotes was
T10464 808-819 JJ denotes significant
T10465 820-823 CC denotes and
T10466 824-838 JJ denotes dose-dependent
T10467 838-839 . denotes .
T10468 840-851 RB denotes Importantly
T10469 851-852 , denotes ,
T10470 853-856 DT denotes the
T10471 857-875 JJ denotes anti-proliferative
T10472 876-882 NN denotes effect
T10473 883-885 IN denotes of
T10474 886-891 NN denotes BMP-6
T10475 892-897 MD denotes could
T10476 898-900 VB denotes be
T10477 901-911 RB denotes completely
T10478 912-923 VBN denotes neutralized
T10479 924-926 IN denotes by
T10480 927-930 DT denotes the
T10481 931-934 NN denotes use
T10482 935-937 IN denotes of
T10483 938-939 DT denotes a
T10484 940-947 JJ denotes natural
T10485 948-957 NN denotes inhibitor
T10486 957-958 , denotes ,
T10487 959-965 NNP denotes Noggin
T10488 965-966 . denotes .
T10489 967-971 DT denotes This
T10490 972-974 VBZ denotes is
T10491 975-977 IN denotes in
T10492 978-982 NN denotes line
T10493 983-987 IN denotes with
T10494 988-994 NNS denotes others
T10495 994-995 , denotes ,
T10496 996-1003 VBG denotes showing
T10497 1004-1008 IN denotes that
T10498 1009-1015 NNP denotes Noggin
T10499 1016-1019 MD denotes can
T10500 1020-1028 VB denotes function
T10501 1029-1031 IN denotes as
T10502 1032-1033 DT denotes a
T10503 1034-1039 NN denotes BMP-6
T10504 1040-1050 NN denotes antagonist
T10505 1051-1052 NNP denotes [
T10506 1052-1057 CD denotes 21,22
T10507 1057-1058 NNP denotes ]
T10508 1058-1059 . denotes .
T10509 1060-1062 IN denotes In
T10510 1063-1071 NN denotes addition
T10511 1071-1072 , denotes ,
T10512 1073-1076 DT denotes the
T10513 1077-1088 NN denotes combination
T10514 1089-1091 IN denotes of
T10515 1092-1099 JJ denotes soluble
T10516 1100-1110 JJ denotes BMP-RIB-Fc
T10517 1111-1114 CC denotes and
T10518 1115-1125 JJ denotes BMP-RII-Fc
T10519 1126-1132 NN denotes fusion
T10520 1133-1141 NNS denotes proteins
T10521 1142-1146 RB denotes also
T10522 1147-1158 VBD denotes neutralized
T10523 1159-1162 DT denotes the
T10524 1163-1181 JJ denotes anti-proliferative
T10525 1182-1188 NN denotes effect
T10526 1189-1191 IN denotes of
T10527 1192-1197 NN denotes BMP-6
T10528 1198-1200 IN denotes in
T10529 1201-1206 JJ denotes human
T10530 1207-1208 NNP denotes B
T10531 1209-1214 NNS denotes cells
T10532 1214-1215 . denotes .
T10533 1216-1229 RB denotes Interestingly
T10534 1229-1230 , denotes ,
T10535 1231-1233 IN denotes as
T10536 1234-1237 IN denotes for
T10537 1238-1243 JJ denotes other
T10538 1244-1247 NNP denotes TGF
T10539 1248-1254 NN denotes family
T10540 1255-1262 NNS denotes members
T10541 1262-1263 , denotes ,
T10542 1264-1276 JJ denotes bifunctional
T10543 1277-1284 NNS denotes effects
T10544 1285-1289 VBP denotes have
T10545 1290-1294 RB denotes also
T10546 1295-1299 VBN denotes been
T10547 1300-1312 VBN denotes demonstrated
T10548 1313-1316 IN denotes for
T10549 1317-1321 NNS denotes BMPs
T10550 1321-1322 . denotes .
T10551 1323-1330 IN denotes Whereas
T10552 1331-1338 JJ denotes several
T10553 1339-1341 IN denotes of
T10554 1342-1345 DT denotes the
T10555 1346-1350 NNS denotes BMPs
T10556 1351-1355 VBP denotes have
T10557 1356-1360 VBN denotes been
T10558 1361-1366 VBN denotes shown
T10559 1367-1369 TO denotes to
T10560 1370-1377 VB denotes promote
T10561 1378-1391 NN denotes proliferation
T10562 1392-1394 IN denotes in
T10563 1395-1402 JJ denotes various
T10564 1403-1407 NN denotes cell
T10565 1408-1413 NNS denotes types
T10566 1414-1423 VBG denotes including
T10567 1424-1435 NNS denotes condrocytes
T10568 1436-1437 NNP denotes [
T10569 1437-1439 CD denotes 23
T10570 1439-1440 NNP denotes ]
T10571 1440-1441 , denotes ,
T10572 1442-1447 NN denotes liver
T10573 1448-1449 NNP denotes [
T10574 1449-1451 CD denotes 24
T10575 1451-1452 NNP denotes ]
T10576 1453-1456 CC denotes and
T10577 1457-1466 NN denotes granulosa
T10578 1467-1472 NNS denotes cells
T10579 1473-1474 NNP denotes [
T10580 1474-1476 CD denotes 25
T10581 1476-1477 NNP denotes ]
T10582 1477-1478 , denotes ,
T10583 1479-1496 JJ denotes antiproliferative
T10584 1497-1504 NNS denotes effects
T10585 1505-1508 CC denotes and
T10586 1509-1518 NN denotes induction
T10587 1519-1521 IN denotes of
T10588 1522-1531 NN denotes apoptosis
T10589 1532-1535 VBZ denotes has
T10590 1536-1540 VBN denotes been
T10591 1541-1549 VBN denotes reported
T10592 1550-1553 IN denotes for
T10593 1554-1555 NNP denotes B
T10594 1556-1559 CC denotes and
T10595 1560-1561 NNP denotes T
T10596 1562-1569 NN denotes lineage
T10597 1570-1575 NNS denotes cells
T10598 1575-1576 . denotes .
T10599 1577-1584 JJ denotes Similar
T10600 1585-1592 NNS denotes effects
T10601 1593-1595 IN denotes as
T10602 1596-1608 VBN denotes demonstrated
T10603 1609-1612 IN denotes for
T10604 1613-1618 NN denotes BMP-6
T10605 1619-1621 IN denotes on
T10606 1622-1627 JJ denotes human
T10607 1628-1629 NNP denotes B
T10608 1630-1635 NNS denotes cells
T10609 1636-1638 IN denotes in
T10610 1639-1642 DT denotes the
T10611 1643-1650 JJ denotes present
T10612 1651-1656 NN denotes study
T10613 1656-1657 , denotes ,
T10614 1658-1662 VBD denotes were
T10615 1663-1675 VBN denotes demonstrated
T10616 1676-1679 IN denotes for
T10617 1680-1685 NNP denotes BMP-2
T10618 1685-1686 , denotes ,
T10619 1687-1688 CD denotes 4
T10620 1688-1689 , denotes ,
T10621 1690-1691 CD denotes 6
T10622 1692-1695 CC denotes and
T10623 1696-1698 CD denotes -7
T10624 1699-1701 IN denotes in
T10625 1702-1707 JJ denotes human
T10626 1708-1715 NN denotes myeloma
T10627 1716-1721 NNS denotes cells
T10628 1722-1723 NNP denotes [
T10629 1723-1727 CD denotes 9-11
T10630 1727-1728 NNP denotes ]
T10631 1728-1729 . denotes .
T10632 1730-1735 JJ denotes Other
T10633 1736-1743 NNS denotes members
T10634 1744-1746 IN denotes of
T10635 1747-1750 DT denotes the
T10636 1751-1761 NNP denotes BMP-family
T10637 1762-1766 VBP denotes have
T10638 1767-1771 RB denotes also
T10639 1772-1776 VBN denotes been
T10640 1777-1785 VBN denotes reported
T10641 1786-1788 TO denotes to
T10642 1789-1795 VB denotes induce
T10643 1796-1805 NN denotes apoptosis
T10644 1805-1806 , denotes ,
T10645 1807-1816 VBG denotes including
T10646 1817-1819 IN denotes in
T10647 1820-1825 NN denotes mouse
T10648 1826-1827 NNP denotes B
T10649 1828-1835 NN denotes lineage
T10650 1836-1841 NNS denotes cells
T10651 1842-1843 NNP denotes [
T10652 1843-1845 CD denotes 26
T10653 1845-1846 NNP denotes ]
T10654 1846-1847 . denotes .
T10655 1848-1860 RB denotes Additionally
T10656 1860-1861 , denotes ,
T10657 1862-1867 JJ denotes BMP-4
T10658 1868-1876 NNS denotes inhibits
T10659 1877-1886 VBP denotes thymocyte
T10660 1887-1900 NN denotes proliferation
T10661 1901-1902 NN denotes [
T10662 1902-1903 CD denotes 6
T10663 1903-1904 NNP denotes ]
T10664 1904-1905 . denotes .
T10665 1906-1911 VBN denotes Taken
T10666 1912-1920 RB denotes together
T10667 1920-1921 , denotes ,
T10668 1922-1927 DT denotes these
T10669 1928-1932 NNS denotes data
T10670 1933-1940 VBP denotes suggest
T10671 1941-1945 IN denotes that
T10672 1946-1949 DT denotes the
T10673 1950-1954 NN denotes role
T10674 1955-1957 IN denotes of
T10675 1958-1962 NNS denotes BMPs
T10676 1963-1965 IN denotes in
T10677 1966-1969 DT denotes the
T10678 1970-1980 NN denotes regulation
T10679 1981-1983 IN denotes of
T10680 1984-1997 NN denotes proliferation
T10681 1998-2001 CC denotes and
T10682 2002-2011 NN denotes apoptosis
T10683 2012-2014 VBZ denotes is
T10684 2015-2021 RB denotes highly
T10685 2022-2026 NN denotes cell
T10686 2027-2031 NN denotes type
T10687 2032-2041 JJ denotes dependent
T10688 2041-2042 . denotes .
T10689 2043-2045 TO denotes To
T10690 2046-2053 VB denotes examine
T10691 2054-2057 WRB denotes how
T10692 2058-2063 JJ denotes BMP-6
T10693 2064-2070 VBZ denotes exerts
T10694 2071-2074 PRP$ denotes its
T10695 2075-2085 JJ denotes functional
T10696 2086-2093 NNS denotes effects
T10697 2094-2096 IN denotes in
T10698 2097-2098 NNP denotes B
T10699 2099-2104 NNS denotes cells
T10700 2104-2105 , denotes ,
T10701 2106-2108 PRP denotes we
T10702 2109-2117 VBD denotes analysed
T10703 2118-2121 NN denotes BMP
T10704 2122-2130 NN denotes receptor
T10705 2131-2141 NN denotes expression
T10706 2142-2144 IN denotes by
T10707 2145-2152 JJ denotes western
T10708 2153-2157 NN denotes blot
T10709 2158-2166 NN denotes analysis
T10710 2166-2167 . denotes .
T10711 2168-2173 NNP denotes Human
T10712 2174-2184 JJ denotes peripheral
T10713 2185-2186 NNP denotes B
T10714 2187-2192 NNS denotes cells
T10715 2193-2197 VBD denotes were
T10716 2198-2203 VBN denotes found
T10717 2204-2206 TO denotes to
T10718 2207-2214 VB denotes express
T10719 2215-2218 DT denotes the
T10720 2219-2222 NN denotes BMP
T10721 2223-2227 NN denotes type
T10722 2228-2229 PRP denotes I
T10723 2230-2239 NNS denotes receptors
T10724 2240-2247 NNP denotes Act-RIA
T10725 2248-2251 CC denotes and
T10726 2252-2259 NNP denotes BMP-RIB
T10727 2259-2260 , denotes ,
T10728 2261-2264 CC denotes and
T10729 2265-2268 DT denotes the
T10730 2269-2273 NN denotes type
T10731 2274-2286 NNS denotes II-receptors
T10732 2287-2294 NNP denotes BMP-RII
T10733 2295-2298 CC denotes and
T10734 2299-2307 NNP denotes Act-RIIb
T10735 2307-2308 , denotes ,
T10736 2309-2314 WDT denotes which
T10737 2315-2321 VBP denotes signal
T10738 2322-2327 IN denotes after
T10739 2328-2335 JJ denotes binding
T10740 2336-2338 IN denotes of
T10741 2339-2346 JJ denotes several
T10742 2347-2351 NNS denotes BMPs
T10743 2351-2352 , denotes ,
T10744 2353-2362 VBG denotes including
T10745 2363-2368 NNP denotes BMP-6
T10746 2369-2370 NNP denotes [
T10747 2370-2375 CD denotes 16,13
T10748 2375-2376 NNP denotes ]
T10749 2376-2377 . denotes .
T10750 2378-2380 TO denotes To
T10751 2381-2388 RBR denotes further
T10752 2389-2396 VB denotes explore
T10753 2397-2402 NNP denotes BMP-6
T10754 2403-2410 JJ denotes induced
T10755 2411-2421 NN denotes signalling
T10756 2421-2422 , denotes ,
T10757 2423-2433 NN denotes activation
T10758 2434-2436 IN denotes of
T10759 2437-2444 JJ denotes several
T10760 2445-2453 NNS denotes pathways
T10761 2454-2456 VBZ denotes is
T10762 2457-2465 JJ denotes possible
T10763 2465-2466 . denotes .
T10764 2467-2470 DT denotes The
T10765 2471-2476 JJ denotes major
T10766 2477-2487 JJ denotes signalling
T10767 2488-2495 NN denotes pathway
T10768 2496-2501 VBN denotes known
T10769 2502-2504 TO denotes to
T10770 2505-2509 NN denotes date
T10771 2509-2510 , denotes ,
T10772 2511-2513 VBZ denotes is
T10773 2514-2524 NN denotes activation
T10774 2525-2527 IN denotes of
T10775 2528-2535 NNS denotes R-Smads
T10776 2536-2537 NNP denotes [
T10777 2537-2542 CD denotes 13,27
T10778 2542-2543 NNP denotes ]
T10779 2543-2544 . denotes .
T10780 2545-2547 IN denotes In
T10781 2548-2552 DT denotes that
T10782 2553-2560 NN denotes respect
T10783 2560-2561 , denotes ,
T10784 2562-2566 NNS denotes BMPs
T10785 2567-2571 VBP denotes have
T10786 2572-2576 VBN denotes been
T10787 2577-2582 VBN denotes shown
T10788 2583-2585 TO denotes to
T10789 2586-2591 VB denotes exert
T10790 2592-2609 JJ denotes antiproliferative
T10791 2610-2617 NNS denotes effects
T10792 2618-2620 IN denotes in
T10793 2621-2622 NNP denotes B
T10794 2623-2630 NN denotes lineage
T10795 2631-2636 NNS denotes cells
T10796 2637-2640 IN denotes via
T10797 2641-2656 NN denotes phosphorylation
T10798 2657-2659 IN denotes of
T10799 2660-2666 JJ denotes R-Smad
T10800 2667-2668 NNP denotes [
T10801 2668-2673 CD denotes 11,28
T10802 2673-2674 NNP denotes ]
T10803 2674-2675 . denotes .
T10804 2676-2687 RB denotes Furthermore
T10805 2687-2688 , denotes ,
T10806 2689-2694 NN denotes BMP-2
T10807 2695-2698 VBZ denotes has
T10808 2699-2703 VBN denotes been
T10809 2704-2709 VBN denotes shown
T10810 2710-2712 TO denotes to
T10811 2713-2719 VB denotes induce
T10812 2720-2730 NN denotes activation
T10813 2731-2733 IN denotes of
T10814 2734-2739 CD denotes STAT3
T10815 2740-2742 IN denotes in
T10816 2743-2750 NN denotes myeloma
T10817 2751-2756 NNS denotes cells
T10818 2757-2758 VBP denotes [
T10819 2758-2759 CD denotes 9
T10820 2759-2760 NNP denotes ]
T10821 2760-2761 . denotes .
T10822 2762-2769 RB denotes However
T10823 2769-2770 , denotes ,
T10824 2771-2786 NN denotes phosphorylation
T10825 2787-2789 IN denotes of
T10826 2790-2796 NN denotes R-Smad
T10827 2797-2800 VBD denotes was
T10828 2801-2804 RB denotes not
T10829 2805-2817 VBN denotes investigated
T10830 2818-2820 IN denotes in
T10831 2821-2825 DT denotes that
T10832 2826-2831 NN denotes study
T10833 2831-2832 . denotes .
T10834 2833-2838 NN denotes BMP-2
T10835 2839-2842 VBZ denotes has
T10836 2843-2847 RB denotes also
T10837 2848-2852 VBN denotes been
T10838 2853-2858 VBN denotes shown
T10839 2859-2861 TO denotes to
T10840 2862-2868 VB denotes induce
T10841 2869-2884 NN denotes phosphorylation
T10842 2885-2887 IN denotes of
T10843 2888-2891 CD denotes p38
T10844 2892-2893 NNP denotes [
T10845 2893-2895 CD denotes 29
T10846 2895-2896 NNP denotes ]
T10847 2896-2897 . denotes .
T10848 2898-2902 RB denotes Thus
T10849 2902-2903 , denotes ,
T10850 2904-2919 NN denotes phosphorylation
T10851 2920-2922 IN denotes of
T10852 2923-2926 CD denotes p38
T10853 2926-2927 , denotes ,
T10854 2928-2933 CD denotes STAT3
T10855 2934-2937 CC denotes and
T10856 2938-2947 CD denotes Smad1/5/8
T10857 2948-2957 VBP denotes represent
T10858 2958-2967 JJ denotes important
T10859 2968-2982 JJ denotes BMP-signalling
T10860 2983-2991 NNS denotes pathways
T10861 2992-2996 WDT denotes that
T10862 2997-3005 VBD denotes mediated
T10863 3006-3009 DT denotes the
T10864 3010-3017 NNS denotes effects
T10865 3018-3020 IN denotes of
T10866 3021-3025 NNS denotes BMPs
T10867 3026-3029 CC denotes and
T10868 3030-3034 RB denotes even
T10869 3035-3045 JJ denotes cross-talk
T10870 3046-3053 IN denotes between
T10871 3054-3059 DT denotes these
T10872 3060-3068 NNS denotes pathways
T10873 3069-3072 VBZ denotes has
T10874 3073-3077 VBN denotes been
T10875 3078-3086 VBN denotes reported
T10876 3087-3088 NNP denotes [
T10877 3088-3093 CD denotes 29,30
T10878 3093-3094 NNP denotes ]
T10879 3094-3095 . denotes .
T10880 3096-3098 IN denotes In
T10881 3099-3102 DT denotes the
T10882 3103-3110 JJ denotes present
T10883 3111-3116 NN denotes study
T10884 3116-3117 , denotes ,
T10885 3118-3120 PRP denotes we
T10886 3121-3125 VBD denotes were
T10887 3126-3129 RB denotes not
T10888 3130-3134 JJ denotes able
T10889 3135-3137 TO denotes to
T10890 3138-3144 VB denotes detect
T10891 3145-3158 JJ denotes BMP-6-induced
T10892 3159-3166 NNS denotes changes
T10893 3167-3169 IN denotes in
T10894 3170-3173 DT denotes the
T10895 3174-3189 NN denotes phosphorylation
T10896 3190-3196 NN denotes status
T10897 3197-3199 IN denotes of
T10898 3200-3205 CD denotes STAT3
T10899 3206-3208 CC denotes or
T10900 3209-3212 CD denotes p38
T10901 3213-3215 IN denotes in
T10902 3216-3221 JJ denotes human
T10903 3222-3232 JJ denotes peripheral
T10904 3233-3234 NNP denotes B
T10905 3235-3240 NNS denotes cells
T10906 3240-3241 . denotes .
T10907 3242-3249 RB denotes Instead
T10908 3249-3250 , denotes ,
T10909 3251-3252 DT denotes a
T10910 3253-3258 JJ denotes rapid
T10911 3259-3262 CC denotes and
T10912 3263-3269 JJ denotes marked
T10913 3270-3285 NN denotes phosphorylation
T10914 3286-3288 IN denotes of
T10915 3289-3298 NNP denotes Smad1/5/8
T10916 3299-3302 VBD denotes was
T10917 3303-3311 VBN denotes revealed
T10918 3311-3312 . denotes .
T10919 3313-3315 IN denotes In
T10920 3316-3317 DT denotes a
T10921 3318-3326 JJ denotes parallel
T10922 3327-3332 NN denotes study
T10923 3332-3333 , denotes ,
T10924 3334-3336 PRP denotes we
T10925 3337-3341 VBP denotes have
T10926 3342-3347 VBN denotes found
T10927 3348-3352 IN denotes that
T10928 3353-3358 JJ denotes other
T10929 3359-3363 NNS denotes BMPs
T10930 3364-3368 RB denotes also
T10931 3369-3376 VBD denotes induced
T10932 3377-3392 NN denotes phosphorylation
T10933 3393-3395 IN denotes of
T10934 3396-3405 NNP denotes Smad1/5/8
T10935 3406-3408 IN denotes in
T10936 3409-3419 JJ denotes peripheral
T10937 3420-3421 NNP denotes B
T10938 3422-3427 NNS denotes cells
T10939 3428-3429 -LRB- denotes (
T10940 3429-3433 NNS denotes data
T10941 3434-3437 RB denotes not
T10942 3438-3443 VBN denotes shown
T10943 3443-3444 -RRB- denotes )
T10944 3444-3445 . denotes .
T10945 3446-3448 PRP denotes We
T10946 3449-3452 VBP denotes are
T10947 3453-3462 RB denotes currently
T10948 3463-3471 VBG denotes pursuing
T10949 3472-3482 NN denotes microarray
T10950 3483-3490 NNS denotes studies
T10951 3491-3493 TO denotes to
T10952 3494-3502 VB denotes identify
T10953 3503-3506 DT denotes the
T10954 3507-3517 JJ denotes signalling
T10955 3518-3526 NNS denotes pathways
T10956 3527-3530 CC denotes and
T10957 3531-3537 NN denotes target
T10958 3538-3543 NNS denotes genes
T10959 3544-3548 WDT denotes that
T10960 3549-3552 VBP denotes are
T10961 3553-3564 RB denotes differently
T10962 3565-3574 VBN denotes regulated
T10963 3575-3577 IN denotes by
T10964 3578-3581 DT denotes the
T10965 3582-3589 JJ denotes various
T10966 3590-3594 NNS denotes BMPs
T10967 3595-3597 IN denotes in
T10968 3598-3603 JJ denotes human
T10969 3604-3605 NNP denotes B
T10970 3606-3611 NNS denotes cells
T10971 3611-3612 . denotes .
T10972 3613-3625 NNP denotes Upregulation
T10973 3626-3628 IN denotes of
T10974 3629-3632 NNP denotes Id1
T10975 3633-3636 IN denotes via
T10976 3637-3646 NNP denotes Smad1/5/8
T10977 3647-3662 NN denotes phosphorylation
T10978 3663-3665 VBZ denotes is
T10979 3666-3667 DT denotes a
T10980 3668-3673 JJ denotes known
T10981 3674-3683 NN denotes mechanism
T10982 3684-3687 IN denotes for
T10983 3688-3693 NNP denotes BMP-6
T10984 3694-3704 VBG denotes signalling
T10985 3705-3707 IN denotes in
T10986 3708-3713 JJ denotes other
T10987 3714-3718 NN denotes cell
T10988 3719-3726 NNS denotes systems
T10989 3727-3728 NNP denotes [
T10990 3728-3733 CD denotes 31,32
T10991 3733-3734 NNP denotes ]
T10992 3735-3738 CC denotes and
T10993 3739-3749 NN denotes regulation
T10994 3750-3752 IN denotes of
T10995 3753-3764 NNS denotes Id-proteins
T10996 3765-3767 VBZ denotes is
T10997 3768-3775 VBN denotes thought
T10998 3776-3778 TO denotes to
T10999 3779-3781 VB denotes be
T11000 3782-3784 DT denotes an
T11001 3785-3794 JJ denotes important
T11002 3795-3804 NN denotes mechanism
T11003 3805-3808 IN denotes for
T11004 3809-3824 JJ denotes Smad-signalling
T11005 3825-3826 NNP denotes [
T11006 3826-3828 CD denotes 17
T11007 3828-3829 NNP denotes ]
T11008 3829-3830 . denotes .
T11009 3831-3833 IN denotes In
T11010 3834-3837 DT denotes the
T11011 3838-3845 JJ denotes present
T11012 3846-3851 NN denotes study
T11013 3851-3852 , denotes ,
T11014 3853-3862 JJ denotes real-time
T11015 3863-3869 NN denotes RT-PCR
T11016 3870-3881 NNS denotes experiments
T11017 3882-3890 VBD denotes revealed
T11018 3891-3892 DT denotes a
T11019 3893-3901 JJ denotes specific
T11020 3902-3911 RB denotes four-fold
T11021 3912-3924 NN denotes upregulation
T11022 3925-3928 IN denotes for
T11023 3929-3932 NNP denotes Id1
T11024 3933-3935 IN denotes in
T11025 3936-3949 NNP denotes BMP-6-treated
T11026 3950-3951 NNP denotes B
T11027 3952-3957 NNS denotes cells
T11028 3957-3958 , denotes ,
T11029 3959-3964 IN denotes while
T11030 3965-3968 DT denotes the
T11031 3969-3975 NN denotes amount
T11032 3976-3978 IN denotes of
T11033 3979-3982 NNP denotes Id2
T11034 3983-3986 JJ denotes Id4
T11035 3987-3995 VBD denotes remained
T11036 3996-4005 JJ denotes unchanged
T11037 4005-4006 . denotes .
T11038 4007-4009 IN denotes In
T11039 4010-4019 NN denotes agreement
T11040 4020-4024 IN denotes with
T11041 4025-4029 DT denotes this
T11042 4029-4030 , denotes ,
T11043 4031-4038 JJ denotes western
T11044 4039-4043 NN denotes blot
T11045 4044-4052 NN denotes analysis
T11046 4053-4065 VBD denotes demonstrated
T11047 4066-4068 DT denotes an
T11048 4069-4081 NN denotes upregulation
T11049 4082-4084 IN denotes of
T11050 4085-4088 JJ denotes Id1
T11051 4089-4096 NN denotes protein
T11052 4096-4097 , denotes ,
T11053 4098-4103 IN denotes while
T11054 4104-4107 DT denotes the
T11055 4108-4114 NN denotes amount
T11056 4115-4117 IN denotes of
T11057 4118-4121 NNP denotes Id2
T11058 4122-4125 CC denotes and
T11059 4126-4129 NNP denotes Id3
T11060 4130-4137 NN denotes protein
T11061 4138-4144 NNS denotes levels
T11062 4145-4153 VBD denotes remained
T11063 4154-4163 JJ denotes unchanged
T11064 4163-4164 . denotes .
T11065 4165-4175 RB denotes Previously
T11066 4175-4176 , denotes ,
T11067 4177-4180 NNP denotes Id1
T11068 4181-4184 VBZ denotes has
T11069 4185-4189 VBN denotes been
T11070 4190-4200 VBN denotes considered
T11071 4201-4204 RB denotes not
T11072 4205-4207 TO denotes to
T11073 4208-4210 VB denotes be
T11074 4211-4220 VBN denotes expressed
T11075 4221-4223 IN denotes in
T11076 4224-4229 JJ denotes later
T11077 4230-4243 JJ denotes developmental
T11078 4244-4250 NNS denotes stages
T11079 4251-4255 IN denotes than
T11080 4256-4261 JJ denotes pro-B
T11081 4262-4267 NNS denotes cells
T11082 4268-4269 NNP denotes [
T11083 4269-4274 CD denotes 33,34
T11084 4274-4275 NNP denotes ]
T11085 4275-4276 , denotes ,
T11086 4277-4280 CC denotes and
T11087 4281-4284 PRP$ denotes its
T11088 4285-4297 JJ denotes constitutive
T11089 4298-4308 NN denotes expression
T11090 4309-4312 VBZ denotes has
T11091 4313-4317 VBN denotes been
T11092 4318-4326 VBN denotes reported
T11093 4327-4329 TO denotes to
T11094 4330-4336 VB denotes impair
T11095 4337-4342 NN denotes mouse
T11096 4343-4344 NNP denotes B
T11097 4345-4349 NN denotes cell
T11098 4350-4361 NN denotes development
T11099 4362-4363 NNP denotes [
T11100 4363-4365 CD denotes 35
T11101 4365-4366 NNP denotes ]
T11102 4366-4367 . denotes .
T11103 4368-4377 RB denotes Therefore
T11104 4377-4378 , denotes ,
T11105 4379-4382 PRP$ denotes our
T11106 4383-4396 NN denotes demonstration
T11107 4397-4399 IN denotes of
T11108 4400-4403 DT denotes the
T11109 4404-4418 JJ denotes time-dependent
T11110 4419-4431 NN denotes upregulation
T11111 4432-4434 IN denotes of
T11112 4435-4438 NNP denotes Id1
T11113 4439-4443 NNP denotes mRNA
T11114 4444-4447 CC denotes and
T11115 4448-4455 NN denotes protein
T11116 4456-4458 IN denotes in
T11117 4459-4465 JJ denotes mature
T11118 4466-4472 JJ denotes normal
T11119 4473-4478 JJ denotes human
T11120 4479-4480 NNP denotes B
T11121 4481-4486 NNS denotes cells
T11122 4487-4489 VBZ denotes is
T11123 4490-4492 IN denotes of
T11124 4493-4503 JJ denotes particular
T11125 4504-4512 NN denotes interest
T11126 4512-4513 . denotes .
T11127 4514-4516 IN denotes In
T11128 4517-4521 DT denotes that
T11129 4522-4529 NN denotes respect
T11130 4529-4530 , denotes ,
T11131 4531-4533 PRP denotes it
T11132 4534-4536 VBZ denotes is
T11133 4537-4547 JJ denotes noteworthy
T11134 4548-4552 IN denotes that
T11135 4553-4558 JJ denotes TGF-β
T11136 4559-4569 NN denotes signalling
T11137 4570-4572 IN denotes in
T11138 4573-4578 JJ denotes early
T11139 4579-4582 CC denotes and
T11140 4583-4589 JJ denotes mature
T11141 4590-4591 NNP denotes B
T11142 4592-4597 NNS denotes cells
T11143 4598-4605 VBZ denotes induces
T11144 4606-4610 DT denotes both
T11145 4611-4614 JJ denotes Id2
T11146 4615-4618 CC denotes and
T11147 4619-4622 JJ denotes Id3
T11148 4623-4633 NN denotes expression
T11149 4634-4635 NNP denotes [
T11150 4635-4640 CD denotes 36,37
T11151 4640-4641 NNP denotes ]
T11152 4641-4642 , denotes ,
T11153 4643-4646 CC denotes but
T11154 4647-4650 RB denotes not
T11155 4651-4654 JJ denotes Id1
T11156 4655-4656 -LRB- denotes (
T11157 4656-4660 NNS denotes data
T11158 4661-4664 RB denotes not
T11159 4665-4670 VBN denotes shown
T11160 4670-4671 -RRB- denotes )
T11161 4671-4672 . denotes .
T11162 4673-4686 RB denotes Interestingly
T11163 4686-4687 , denotes ,
T11164 4688-4693 DT denotes these
T11165 4694-4701 NNS denotes results
T11166 4702-4706 VBP denotes show
T11167 4707-4711 IN denotes that
T11168 4712-4719 JJ denotes various
T11169 4720-4727 NNS denotes members
T11170 4728-4730 IN denotes of
T11171 4731-4734 DT denotes the
T11172 4735-4740 NNP denotes TGF-β
T11173 4741-4747 NN denotes family
T11174 4748-4756 VB denotes regulate
T11175 4757-4759 NN denotes Id
T11176 4760-4768 NNS denotes proteins
T11177 4769-4780 RB denotes differently
T11178 4780-4781 . denotes .
T11179 4782-4785 NNP denotes Id2
T11180 4786-4789 CC denotes and
T11181 4790-4793 NNP denotes Id3
T11182 4794-4797 VBP denotes are
T11183 4798-4808 VBN denotes considered
T11184 4809-4811 TO denotes to
T11185 4812-4814 VB denotes be
T11186 4815-4818 DT denotes the
T11187 4819-4821 NN denotes Id
T11188 4822-4830 VBZ denotes proteins
T11189 4831-4837 RB denotes mainly
T11190 4838-4847 VBN denotes expressed
T11191 4848-4850 IN denotes in
T11192 4851-4857 JJ denotes mature
T11193 4858-4859 NNP denotes B
T11194 4860-4865 NNS denotes cells
T11195 4866-4867 NNP denotes [
T11196 4867-4869 CD denotes 38
T11197 4869-4870 NNP denotes ]
T11198 4870-4871 . denotes .
T11199 4872-4875 DT denotes The
T11200 4876-4883 JJ denotes present
T11201 4884-4889 NN denotes study
T11202 4890-4894 RB denotes also
T11203 4895-4900 VBD denotes found
T11204 4901-4904 NNP denotes Id2
T11205 4905-4908 CC denotes and
T11206 4909-4912 NNP denotes Id3
T11207 4913-4920 NN denotes protein
T11208 4921-4923 IN denotes in
T11209 4924-4925 NNP denotes B
T11210 4926-4931 NNS denotes cells
T11211 4932-4934 TO denotes to
T11212 4935-4937 VB denotes be
T11213 4938-4942 RBR denotes more
T11214 4943-4949 RB denotes highly
T11215 4950-4959 VBN denotes expressed
T11216 4960-4964 IN denotes than
T11217 4965-4968 JJ denotes Id1
T11218 4969-4971 IN denotes in
T11219 4972-4979 VBG denotes resting
T11220 4980-4981 NNP denotes B
T11221 4982-4987 NNS denotes cells
T11222 4987-4988 . denotes .
T11223 4989-4996 RB denotes However
T11224 4996-4997 , denotes ,
T11225 4998-5003 NNP denotes BMP-6
T11226 5004-5007 VBD denotes did
T11227 5008-5011 RB denotes not
T11228 5012-5018 VB denotes induce
T11229 5019-5030 JJ denotes significant
T11230 5031-5038 NNS denotes changes
T11231 5039-5041 IN denotes in
T11232 5042-5045 DT denotes the
T11233 5046-5053 NN denotes protein
T11234 5054-5064 NN denotes expression
T11235 5065-5067 IN denotes of
T11236 5068-5071 NNP denotes Id2
T11237 5072-5075 CC denotes and
T11238 5076-5079 NNP denotes Id3
T11239 5079-5080 . denotes .
T11240 5081-5083 PRP denotes It
T11241 5084-5086 VBZ denotes is
T11242 5087-5095 VBN denotes believed
T11243 5096-5100 IN denotes that
T11244 5101-5103 NN denotes Id
T11245 5104-5112 NNS denotes proteins
T11246 5113-5118 VBP denotes block
T11247 5119-5134 NN denotes differentiation
T11248 5135-5138 CC denotes and
T11249 5139-5146 VB denotes promote
T11250 5147-5160 NN denotes proliferation
T11251 5161-5163 IN denotes in
T11252 5164-5171 JJ denotes various
T11253 5172-5176 NN denotes cell
T11254 5177-5182 NNS denotes types
T11255 5183-5184 NNP denotes [
T11256 5184-5189 CD denotes 39,33
T11257 5189-5190 NNP denotes ]
T11258 5190-5191 . denotes .
T11259 5192-5194 NN denotes Id
T11260 5195-5203 NNS denotes proteins
T11261 5204-5207 VBP denotes act
T11262 5208-5210 IN denotes as
T11263 5211-5228 JJ denotes dominant-negative
T11264 5229-5239 NNS denotes inhibitors
T11265 5240-5242 IN denotes of
T11266 5243-5253 NNS denotes E-proteins
T11267 5254-5257 CC denotes and
T11268 5258-5262 NNS denotes Pax5
T11269 5263-5271 NN denotes function
T11270 5272-5274 IN denotes by
T11271 5275-5282 VBG denotes forming
T11272 5283-5289 NNS denotes dimers
T11273 5290-5294 IN denotes with
T11274 5295-5300 DT denotes these
T11275 5301-5309 NNS denotes proteins
T11276 5309-5310 , denotes ,
T11277 5311-5317 VBG denotes making
T11278 5318-5322 PRP denotes them
T11279 5323-5329 JJ denotes unable
T11280 5330-5332 TO denotes to
T11281 5333-5337 NN denotes bind
T11282 5338-5341 NN denotes DNA
T11283 5341-5342 . denotes .
T11284 5343-5345 PRP denotes It
T11285 5346-5349 VBZ denotes has
T11286 5350-5354 VBN denotes been
T11287 5355-5363 VBN denotes proposed
T11288 5364-5368 IN denotes that
T11289 5369-5372 DT denotes the
T11290 5373-5380 NN denotes balance
T11291 5381-5386 IN denotes among
T11292 5387-5397 NNS denotes E-proteins
T11293 5397-5398 , denotes ,
T11294 5399-5403 NNS denotes Pax5
T11295 5404-5407 CC denotes and
T11296 5408-5410 NN denotes Id
T11297 5411-5419 NNS denotes proteins
T11298 5420-5425 MD denotes might
T11299 5426-5430 VB denotes have
T11300 5431-5433 DT denotes an
T11301 5434-5443 JJ denotes important
T11302 5444-5448 NN denotes role
T11303 5449-5451 IN denotes in
T11304 5452-5461 VBN denotes activated
T11305 5462-5463 NNP denotes B
T11306 5464-5469 NNS denotes cells
T11307 5470-5471 NNP denotes [
T11308 5471-5473 CD denotes 38
T11309 5473-5474 NNP denotes ]
T11310 5474-5475 . denotes .
T11311 5476-5478 IN denotes In
T11312 5479-5483 DT denotes that
T11313 5484-5491 NN denotes respect
T11314 5491-5492 , denotes ,
T11315 5493-5503 NNS denotes E-proteins
T11316 5504-5508 VBP denotes have
T11317 5509-5513 VBN denotes been
T11318 5514-5524 VBN denotes implicated
T11319 5525-5527 IN denotes in
T11320 5528-5532 DT denotes both
T11321 5533-5536 DT denotes the
T11322 5537-5546 NN denotes promotion
T11323 5547-5550 CC denotes and
T11324 5551-5561 NN denotes inhibition
T11325 5562-5564 IN denotes of
T11326 5565-5569 NN denotes cell
T11327 5570-5578 NN denotes survival
T11328 5579-5582 CC denotes and
T11329 5583-5589 NN denotes growth
T11330 5590-5592 IN denotes at
T11331 5593-5602 JJ denotes different
T11332 5603-5609 NNS denotes points
T11333 5610-5612 IN denotes in
T11334 5613-5623 NN denotes lymphocyte
T11335 5624-5635 NN denotes development
T11336 5636-5637 NNP denotes [
T11337 5637-5639 CD denotes 40
T11338 5639-5640 NNP denotes ]
T11339 5640-5641 . denotes .
T11340 5642-5645 DT denotes The
T11341 5646-5663 JJ denotes antiproliferative
T11342 5664-5667 CC denotes and
T11343 5668-5673 NN denotes death
T11344 5674-5682 VBG denotes inducing
T11345 5683-5689 NN denotes effect
T11346 5690-5692 IN denotes of
T11347 5693-5698 NN denotes BMP-6
T11348 5699-5701 IN denotes in
T11349 5702-5703 NNP denotes B
T11350 5704-5709 NNS denotes cells
T11351 5710-5714 IN denotes with
T11352 5715-5726 JJ denotes concomitant
T11353 5727-5739 NN denotes upregulation
T11354 5740-5742 IN denotes of
T11355 5743-5746 JJ denotes Id1
T11356 5747-5754 NN denotes protein
T11357 5755-5757 VBZ denotes is
T11358 5758-5767 RB denotes therefore
T11359 5768-5770 IN denotes in
T11360 5771-5775 NN denotes line
T11361 5776-5780 IN denotes with
T11362 5781-5784 DT denotes the
T11363 5785-5789 NN denotes view
T11364 5790-5794 IN denotes that
T11365 5795-5797 NN denotes Id
T11366 5798-5806 NNS denotes proteins
T11367 5807-5810 VBP denotes are
T11368 5811-5819 VBN denotes required
T11369 5820-5823 IN denotes for
T11370 5824-5827 DT denotes the
T11371 5828-5837 NN denotes induction
T11372 5838-5840 IN denotes of
T11373 5841-5847 NN denotes growth
T11374 5848-5854 NN denotes arrest
T11375 5855-5858 CC denotes and
T11376 5859-5868 NN denotes apoptosis
T11377 5869-5871 IN denotes in
T11378 5872-5884 JJ denotes B-lymphocyte
T11379 5885-5896 NNS denotes progenitors
T11380 5897-5899 IN denotes by
T11381 5900-5905 NNP denotes TGF-β
T11382 5906-5907 NNP denotes [
T11383 5907-5909 CD denotes 40
T11384 5909-5910 NNP denotes ]
T11385 5910-5911 . denotes .
T11386 5912-5923 RB denotes Furthermore
T11387 5923-5924 , denotes ,
T11388 5925-5927 NN denotes Id
T11389 5928-5936 NNS denotes proteins
T11390 5937-5940 VBP denotes are
T11391 5941-5946 VBN denotes known
T11392 5947-5949 IN denotes as
T11393 5950-5959 JJ denotes important
T11394 5960-5965 NNS denotes parts
T11395 5966-5968 IN denotes of
T11396 5969-5979 VBG denotes signalling
T11397 5980-5988 NNS denotes pathways
T11398 5989-5997 VBN denotes involved
T11399 5998-6000 IN denotes in
T11400 6001-6012 NN denotes development
T11401 6012-6013 , denotes ,
T11402 6014-6018 NN denotes cell
T11403 6019-6024 NN denotes cycle
T11404 6025-6028 CC denotes and
T11405 6029-6042 NN denotes tumorigenesis
T11406 6043-6044 NNP denotes [
T11407 6044-6046 CD denotes 32
T11408 6046-6047 NNP denotes ]
T11409 6047-6048 . denotes .
T11410 6049-6051 PRP denotes It
T11411 6052-6054 VBZ denotes is
T11412 6055-6059 RB denotes well
T11413 6060-6071 VBN denotes established
T11414 6072-6076 IN denotes that
T11415 6077-6084 JJ denotes various
T11416 6085-6092 NNS denotes members
T11417 6093-6095 IN denotes of
T11418 6096-6099 DT denotes the
T11419 6100-6102 NN denotes Id
T11420 6103-6109 NN denotes family
T11421 6110-6113 VBP denotes are
T11422 6114-6127 VBN denotes overexpressed
T11423 6128-6130 IN denotes in
T11424 6131-6132 DT denotes a
T11425 6133-6138 NN denotes range
T11426 6139-6141 IN denotes of
T11427 6142-6147 JJ denotes human
T11428 6148-6155 NNS denotes tumours
T11429 6156-6159 CC denotes and
T11430 6160-6169 RB denotes generally
T11431 6169-6170 , denotes ,
T11432 6171-6174 JJ denotes Id1
T11433 6175-6182 VBZ denotes appears
T11434 6183-6185 TO denotes to
T11435 6186-6188 VB denotes be
T11436 6189-6192 DT denotes the
T11437 6193-6199 NN denotes family
T11438 6200-6206 NN denotes member
T11439 6207-6211 RBS denotes most
T11440 6212-6218 RB denotes widely
T11441 6219-6232 VBN denotes overexpressed
T11442 6233-6235 IN denotes in
T11443 6236-6237 DT denotes a
T11444 6238-6245 NN denotes variety
T11445 6246-6248 IN denotes of
T11446 6249-6254 JJ denotes human
T11447 6255-6267 NNS denotes malignancies
T11448 6268-6269 NNP denotes [
T11449 6269-6271 CD denotes 41
T11450 6271-6272 NNP denotes ]
T11451 6272-6273 , denotes ,
T11452 6274-6283 VBG denotes including
T11453 6284-6292 JJ denotes multiple
T11454 6293-6300 NN denotes myeloma
T11455 6301-6302 NNP denotes [
T11456 6302-6307 CD denotes 42,32
T11457 6307-6308 NNP denotes ]
T11458 6308-6309 . denotes .
T11459 6310-6322 RB denotes Additionally
T11460 6322-6323 , denotes ,
T11461 6324-6327 PRP$ denotes our
T11462 6328-6336 NNS denotes findings
T11463 6337-6341 WDT denotes that
T11464 6342-6347 NNP denotes BMP-6
T11465 6348-6357 VBZ denotes activates
T11466 6358-6371 JJ denotes intracellular
T11467 6372-6382 JJ denotes signalling
T11468 6383-6391 NNS denotes pathways
T11469 6392-6394 IN denotes in
T11470 6395-6400 JJ denotes human
T11471 6401-6402 NNP denotes B
T11472 6403-6408 NNS denotes cells
T11473 6409-6414 MD denotes might
T11474 6415-6417 VB denotes be
T11475 6418-6420 IN denotes of
T11476 6421-6430 JJ denotes potential
T11477 6431-6449 JJ denotes pathophysiological
T11478 6450-6462 NN denotes significance
T11479 6463-6465 IN denotes in
T11480 6466-6474 NN denotes lymphoma
T11481 6475-6478 CC denotes and
T11482 6479-6491 NN denotes inflammation
T11483 6491-6492 . denotes .
T11484 6493-6497 NNP denotes High
T11485 6498-6503 NNP denotes BMP-6
T11486 6504-6508 NNP denotes mRNA
T11487 6509-6519 NN denotes expression
T11488 6520-6522 IN denotes in
T11489 6523-6528 NNP denotes DLBCL
T11490 6529-6532 VBZ denotes has
T11491 6533-6537 VBN denotes been
T11492 6538-6543 VBN denotes shown
T11493 6544-6546 TO denotes to
T11494 6547-6556 VB denotes correlate
T11495 6557-6559 TO denotes to
T11496 6560-6572 JJ denotes unfavourable
T11497 6573-6580 NN denotes outcome
T11498 6581-6582 NNP denotes [
T11499 6582-6584 CD denotes 12
T11500 6584-6585 NNP denotes ]
T11501 6585-6586 . denotes .
T11502 6587-6589 IN denotes In
T11503 6590-6594 DT denotes this
T11504 6595-6602 NN denotes respect
T11505 6602-6603 , denotes ,
T11506 6604-6606 PRP denotes it
T11507 6607-6609 VBZ denotes is
T11508 6610-6612 IN denotes of
T11509 6613-6621 NN denotes interest
T11510 6622-6626 IN denotes that
T11511 6627-6635 JJ denotes targeted
T11512 6636-6646 NN denotes expression
T11513 6647-6649 IN denotes of
T11514 6650-6653 NNP denotes Id1
T11515 6654-6656 TO denotes to
T11516 6657-6670 NNS denotes B-lymphocytes
T11517 6671-6679 VBD denotes resulted
T11518 6680-6682 IN denotes in
T11519 6683-6691 JJ denotes aberrant
T11520 6692-6693 NNP denotes B
T11521 6694-6698 NN denotes cell
T11522 6699-6710 NN denotes development
T11523 6710-6711 , denotes ,
T11524 6712-6719 JJ denotes massive
T11525 6720-6729 NN denotes apoptosis
T11526 6729-6730 , denotes ,
T11527 6731-6734 CC denotes and
T11528 6735-6745 JJ denotes subsequent
T11529 6746-6757 NN denotes development
T11530 6758-6760 IN denotes of
T11531 6761-6762 NNP denotes B
T11532 6763-6767 NN denotes cell
T11533 6768-6777 NNS denotes lymphomas
T11534 6778-6779 NNP denotes [
T11555 6864-6869 CD denotes 43,44
T11556 6869-6870 NNP denotes ]
T11557 6871-6874 CC denotes and
T11558 6875-6883 JJ denotes elevated
T11559 6884-6890 NNS denotes levels
T11560 6891-6893 IN denotes of
T11561 6894-6897 NNP denotes Id1
T11562 6898-6901 CC denotes and
T11563 6902-6905 NNP denotes Id3
T11564 6906-6910 VBP denotes have
T11565 6911-6915 VBN denotes been
T11566 6916-6921 VBN denotes found
T11567 6922-6924 IN denotes in
T11568 6925-6928 DT denotes the
T11569 6929-6936 NN denotes synovia
T11570 6937-6939 IN denotes of
T11571 6940-6951 NNS denotes RA-patients
T11572 6952-6953 NNP denotes [
T11573 6953-6955 CD denotes 45
T11574 6955-6956 NNP denotes ]
T11575 6956-6957 . denotes .
T11576 6958-6968 RB denotes Altogether
T11577 6968-6969 , denotes ,
T11578 6970-6975 DT denotes these
T11579 6976-6983 NNS denotes results
T11580 6984-6989 NN denotes point
T11581 6990-6992 TO denotes to
T11582 6993-6995 DT denotes an
T11583 6996-7005 JJ denotes important
T11584 7006-7010 NN denotes role
T11585 7011-7014 IN denotes for
T11586 7015-7017 NN denotes Id
T11587 7018-7026 NNS denotes proteins
T11588 7027-7029 IN denotes in
T11589 7030-7033 DT denotes the
T11590 7034-7044 NN denotes regulation
T11591 7045-7047 IN denotes of
T11592 7048-7054 JJ denotes normal
T11593 7055-7056 NNP denotes B
T11594 7057-7061 NN denotes cell
T11595 7062-7073 NN denotes homeostasis
T11596 7074-7077 CC denotes and
T11597 7078-7080 IN denotes in
T11598 7081-7089 NNS denotes diseases
T11599 7089-7090 , denotes ,
T11600 7091-7096 WRB denotes where
T11601 7097-7098 NNP denotes B
T11602 7099-7104 NNS denotes cells
T11603 7105-7108 VBP denotes are
T11604 7109-7117 VBN denotes involved
T11605 7117-7118 . denotes .
T11606 7119-7121 PRP denotes It
T11607 7122-7126 MD denotes will
T11608 7127-7136 RB denotes therefore
T11609 7137-7139 VB denotes be
T11610 7140-7149 JJ denotes important
T11611 7150-7152 TO denotes to
T11612 7153-7160 RBR denotes further
T11613 7161-7170 VB denotes elucidate
T11614 7171-7174 DT denotes the
T11615 7175-7179 NN denotes role
T11616 7180-7182 IN denotes of
T11617 7183-7187 NN denotes Id-1
T11618 7188-7190 IN denotes in
T11619 7191-7196 JJ denotes human
T11620 7197-7198 NNP denotes B
T11621 7199-7204 NNS denotes cells
T11622 7205-7207 IN denotes by
T11623 7208-7217 JJ denotes selective
T11624 7218-7222 IN denotes over
T11625 7223-7233 NN denotes expression
T11626 7234-7236 CC denotes or
T11627 7237-7247 NN denotes inhibition
T11628 7248-7250 IN denotes of
T11629 7251-7255 JJ denotes Id-1
T11630 7256-7260 NN denotes gene
T11631 7261-7271 NN denotes expression
T11632 7271-7272 . denotes .
T11633 7273-7278 VBN denotes Given
T11634 7279-7282 DT denotes the
T11635 7283-7287 NN denotes role
T11636 7288-7290 IN denotes of
T11637 7291-7296 NNP denotes BMP-6
T11638 7297-7299 IN denotes in
T11639 7300-7306 NNP denotes mature
T11640 7307-7312 JJ denotes human
T11641 7313-7314 NNP denotes B
T11642 7315-7320 NNS denotes cells
T11643 7321-7333 VBD denotes demonstrated
T11644 7334-7338 RB denotes here
T11645 7338-7339 , denotes ,
T11646 7340-7354 NN denotes identification
T11647 7355-7357 IN denotes of
T11648 7358-7363 NNP denotes BMP-6
T11649 7364-7373 VBG denotes producing
T11650 7374-7379 NNS denotes cells
T11651 7380-7382 IN denotes in
T11652 7383-7387 NN denotes vivo
T11653 7388-7392 IN denotes with
T11654 7393-7404 NN denotes possibility
T11655 7405-7407 IN denotes of
T11656 7408-7419 NN denotes interaction
T11657 7420-7424 IN denotes with
T11658 7425-7430 NN denotes naïve
T11659 7431-7434 CC denotes and
T11660 7435-7441 NN denotes memory
T11661 7442-7443 NNP denotes B
T11662 7444-7449 NNS denotes cells
T11663 7450-7455 MD denotes might
T11664 7456-7466 VB denotes contribute
T11665 7467-7469 TO denotes to
T11666 7470-7473 DT denotes the
T11667 7474-7487 NN denotes understanding
T11668 7488-7490 IN denotes of
T11669 7491-7497 JJ denotes mature
T11670 7498-7499 NNP denotes B
T11671 7500-7504 NN denotes cell
T11672 7505-7512 NN denotes biology
T11673 7512-7513 . denotes .
T11674 7514-7518 NNP denotes High
T11675 7519-7524 NNP denotes BMP-6
T11676 7525-7529 NNP denotes mRNA
T11677 7530-7540 NN denotes expression
T11678 7541-7543 IN denotes in
T11679 7544-7549 NNP denotes DLBCL
T11680 7550-7553 VBZ denotes has
T11681 7554-7558 VBN denotes been
T11682 7559-7567 VBN denotes detected
T11683 7568-7570 IN denotes by
T11684 7571-7575 NN denotes gene
T11685 7576-7586 NN denotes expression
T11686 7587-7596 VBG denotes profiling
T11687 7597-7598 NNP denotes [
T11688 7598-7600 CD denotes 12
T11689 7600-7601 NNP denotes ]
T11690 7601-7602 . denotes .
T11691 7603-7614 RB denotes Furthermore
T11692 7614-7615 , denotes ,
T11693 7616-7626 NN denotes production
T11694 7627-7629 IN denotes of
T11695 7630-7635 NNP denotes BMP-6
T11696 7636-7647 NNS denotes transcripts
T11697 7648-7650 IN denotes in
T11698 7651-7657 JJ denotes normal
T11699 7658-7667 VBN denotes activated
T11700 7668-7669 NNP denotes B
T11701 7670-7675 NNS denotes cells
T11702 7676-7679 VBD denotes was
T11703 7680-7688 VBN denotes detected
T11704 7689-7691 IN denotes in
T11705 7692-7695 DT denotes the
T11706 7696-7700 JJ denotes same
T11707 7701-7706 NN denotes study
T11708 7706-7707 . denotes .
T11709 7708-7710 IN denotes Of
T11710 7711-7715 NN denotes note
T11742 7881-7886 NN denotes BMP-6
T11743 7887-7891 NN denotes loop
T11744 7892-7894 IN denotes in
T11745 7895-7900 JJ denotes human
T11746 7901-7902 NNP denotes B
T11747 7903-7908 NNS denotes cells
T11748 7908-7909 . denotes .
T11749 7910-7912 PRP denotes We
T11750 7913-7921 VBD denotes analysed
T11751 7922-7925 DT denotes the
T11752 7926-7936 NN denotes expression
T11753 7937-7942 NNP denotes BMP-6
T11754 7943-7947 NNP denotes mRNA
T11755 7948-7950 IN denotes in
T11756 7951-7961 JJ denotes peripheral
T11757 7962-7967 NN denotes blood
T11758 7968-7969 NNP denotes B
T11759 7970-7975 NNS denotes cells
T11760 7976-7978 IN denotes by
T11761 7979-7988 JJ denotes real-time
T11762 7989-7992 NNP denotes PCR
T11763 7992-7993 , denotes ,
T11764 7994-7997 CC denotes and
T11765 7998-8004 NN denotes report
T11766 8005-8009 RB denotes here
T11767 8010-8013 DT denotes the
T11768 8014-8026 NN denotes upregulation
T11769 8027-8029 IN denotes of
T11770 8030-8040 JJ denotes endogenous
T11771 8041-8046 NN denotes BMP-6
T11772 8047-8058 NNS denotes transcripts
T11773 8059-8064 IN denotes after
T11774 8065-8076 NN denotes stimulation
T11775 8077-8081 IN denotes with
T11776 8082-8085 NNP denotes FCS
T11777 8085-8086 , denotes ,
T11778 8087-8092 JJ denotes human
T11779 8093-8101 NNP denotes AB-serum
T11780 8102-8105 CC denotes and
T11781 8105-8106 , denotes ,
T11782 8107-8111 RBS denotes most
T11783 8112-8123 RB denotes importantly
T11784 8123-8124 , denotes ,
T11785 8125-8133 JJ denotes anti-IgM
T11786 8133-8134 . denotes .
T11787 8135-8142 RB denotes However
T11788 8142-8143 , denotes ,
T11789 8144-8147 PRP$ denotes our
T11790 8148-8156 NNS denotes attempts
T11791 8157-8159 TO denotes to
T11792 8160-8165 VB denotes study
T11793 8166-8171 NNP denotes BMP-6
T11794 8172-8179 NN denotes protein
T11795 8180-8186 NNS denotes levels
T11796 8187-8191 VBD denotes were
T11797 8192-8204 JJ denotes unsuccessful
T11798 8205-8208 JJ denotes due
T11799 8209-8211 TO denotes to
T11800 8212-8220 NNS denotes problems
T11801 8221-8225 IN denotes with
T11802 8226-8236 JJ denotes unspecific
T11803 8237-8244 JJ denotes binding
T11804 8245-8247 IN denotes of
T11805 8248-8251 DT denotes the
T11806 8252-8262 JJ denotes anti-BMP-6
T11807 8263-8273 NNS denotes antibodies
T11808 8274-8280 VBN denotes tested
T11809 8280-8281 , denotes ,
T11810 8282-8285 CC denotes and
T11811 8286-8290 NN denotes lack
T11812 8291-8293 IN denotes of
T11813 8294-8302 JJ denotes specific
T11814 8303-8311 VBG denotes staining
T11815 8312-8314 IN denotes in
T11816 8315-8322 NN denotes control
T11817 8323-8328 NNS denotes cells
T11818 8329-8334 VBN denotes known
T11819 8335-8337 TO denotes to
T11820 8338-8345 VB denotes express
T11821 8346-8351 NNP denotes BMP-6
T11822 8352-8356 NNP denotes mRNA
T11823 8356-8357 . denotes .
T11824 8358-8360 IN denotes In
T11825 8361-8369 NN denotes contrast
T11826 8369-8370 , denotes ,
T11827 8371-8374 DT denotes the
T11828 8375-8386 JJ denotes recombinant
T11829 8387-8394 NN denotes protein
T11830 8395-8398 VBD denotes was
T11831 8399-8406 RB denotes readily
T11832 8407-8415 VBN denotes detected
T11833 8415-8416 . denotes .
T11834 8417-8419 IN denotes In
T11835 8420-8424 DT denotes that
T11836 8425-8432 NN denotes respect
T11837 8432-8433 , denotes ,
T11838 8434-8437 JJ denotes few
T11839 8438-8451 NNS denotes investigators
T11840 8452-8456 VBP denotes have
T11841 8457-8465 VBN denotes detected
T11842 8466-8471 NNP denotes BMP-6
T11843 8472-8479 NN denotes protein
T11844 8480-8482 IN denotes in
T11845 8483-8489 NNS denotes humans
T11846 8489-8490 , denotes ,
T11847 8491-8501 RB denotes especially
T11848 8502-8504 IN denotes in
T11849 8505-8519 JJ denotes non-pathogenic
T11850 8520-8526 NN denotes tissue
T11851 8526-8527 . denotes .
T11852 8528-8531 DT denotes The
T11853 8532-8543 NN denotes possibility
T11854 8544-8546 IN denotes of
T11855 8547-8552 NN denotes BMP-6
T11856 8553-8563 NN denotes production
T11857 8564-8566 IN denotes in
T11858 8567-8572 JJ denotes human
T11859 8573-8580 NNPS denotes B-cells
T11860 8581-8583 VBZ denotes is
T11861 8584-8586 IN denotes in
T11862 8587-8591 NN denotes line
T11863 8592-8596 IN denotes with
T11864 8597-8598 DT denotes a
T11865 8599-8605 JJ denotes recent
T11866 8606-8610 NN denotes work
T11867 8611-8615 WDT denotes that
T11868 8616-8624 VBD denotes reported
T11869 8625-8628 DT denotes the
T11870 8629-8639 NN denotes production
T11871 8640-8642 IN denotes of
T11872 8643-8648 NN denotes BMP-6
T11873 8649-8651 IN denotes in
T11874 8652-8657 NN denotes mouse
T11875 8658-8659 NNP denotes B
T11876 8660-8665 NNS denotes cells
T11877 8665-8666 , denotes ,
T11878 8667-8679 VBG denotes infiltrating
T11879 8680-8683 DT denotes the
T11880 8684-8688 NN denotes bone
T11881 8689-8695 NN denotes marrow
T11882 8696-8698 IN denotes of
T11883 8699-8703 NNS denotes mice
T11884 8704-8708 IN denotes with
T11885 8709-8721 JJ denotes inflammatory
T11886 8722-8731 NNS denotes arthritis
T11887 8732-8733 NNP denotes [
T11888 8733-8735 CD denotes 43
T11889 8735-8736 NNP denotes ]
T11890 8736-8737 . denotes .
T11891 8738-8740 IN denotes In
T11892 8741-8745 DT denotes this
T11893 8746-8751 NN denotes study
T11894 8751-8752 , denotes ,
T11895 8753-8754 DT denotes a
T11896 8755-8759 NN denotes role
T11897 8760-8763 IN denotes for
T11898 8764-8768 NNS denotes BMPs
T11899 8769-8771 IN denotes in
T11900 8772-8775 DT denotes the
T11901 8776-8789 JJ denotes inflammatoric
T11902 8790-8797 NN denotes process
T11903 8798-8800 IN denotes of
T11904 8801-8810 NN denotes arthritis
T11905 8811-8814 VBD denotes was
T11906 8815-8824 VBN denotes suggested
T11907 8824-8825 . denotes .
T11908 8826-8829 DT denotes The
T11909 8830-8842 NN denotes upregulation
T11910 8843-8845 IN denotes of
T11911 8846-8849 DT denotes the
T11912 8850-8867 NNS denotes BMP-6-transcripts
T11913 8868-8873 IN denotes after
T11914 8874-8890 NNP denotes IgM-crosslinking
T11915 8891-8893 VBZ denotes is
T11916 8894-8896 IN denotes of
T11917 8897-8913 JJ denotes pathophysiologic
T11918 8914-8922 NN denotes interest
T11919 8923-8924 NNP denotes [
T11920 8924-8926 CD denotes 12
T11921 8926-8927 NNP denotes ]
T11922 8927-8928 . denotes .
T11923 8929-8930 DT denotes A
T11924 8931-8935 NN denotes loss
T11925 8936-8938 IN denotes of
T11926 8939-8959 NN denotes TGF-β-responsiveness
T11927 8960-8963 VBZ denotes has
T11928 8964-8968 VBN denotes been
T11929 8969-8978 VBN denotes suggested
T11930 8979-8981 TO denotes to
T11931 8982-8984 VB denotes be
T11932 8985-8986 DT denotes a
T11933 8987-8995 JJ denotes critical
T11934 8996-9008 NN denotes contribution
T11935 9009-9011 TO denotes to
T11936 9012-9021 JJ denotes malignant
T11937 9022-9036 NN denotes transformation
T11938 9037-9038 NNP denotes [
T11939 9038-9043 CD denotes 47,48
T11940 9043-9044 NNP denotes ]
T11941 9045-9048 CC denotes and
T11942 9049-9056 JJ denotes similar
T11943 9057-9066 JJ denotes oncogenic
T11944 9067-9077 NNS denotes mechanisms
T11945 9078-9082 VBP denotes have
T11946 9083-9087 VBN denotes been
T11947 9088-9098 VBN denotes postulated
T11948 9099-9102 IN denotes for
T11949 9103-9107 NNS denotes BMPs
T11950 9107-9108 . denotes .
T11951 9109-9114 NNS denotes Lines
T11952 9115-9117 IN denotes of
T11953 9118-9126 NN denotes evidence
T11954 9127-9134 VBP denotes suggest
T11955 9135-9136 NNP denotes [
T11956 9136-9138 CD denotes 49
T11957 9138-9139 NN denotes ]
T11958 9140-9144 WDT denotes that
T11959 9145-9147 IN denotes at
T11960 9148-9153 JJ denotes early
T11961 9154-9160 NNS denotes stages
T11962 9161-9163 IN denotes of
T11963 9164-9178 NN denotes carcinogenesis
T11964 9178-9179 , denotes ,
T11965 9180-9185 NNP denotes BMP-6
T11966 9186-9188 VBZ denotes is
T11967 9189-9192 RB denotes not
T11968 9193-9194 DT denotes a
T11969 9195-9201 NN denotes tumour
T11970 9202-9210 NN denotes promoter
T11971 9210-9211 , denotes ,
T11972 9212-9215 CC denotes but
T11973 9216-9226 VBZ denotes suppresses
T11974 9227-9233 JJ denotes benign
T11975 9234-9237 CC denotes and
T11976 9238-9247 JJ denotes malignant
T11977 9248-9254 NN denotes tumour
T11978 9255-9264 NN denotes outgrowth
T11979 9264-9265 . denotes .
T11980 9266-9271 DT denotes These
T11981 9272-9280 NNS denotes findings
T11982 9281-9284 VBP denotes are
T11983 9285-9287 IN denotes in
T11984 9288-9292 JJ denotes good
T11985 9293-9302 NN denotes agreement
T11986 9303-9307 IN denotes with
T11987 9308-9316 JJ denotes previous
T11988 9317-9325 NNS denotes findings
T11989 9326-9329 IN denotes for
T11990 9330-9335 JJ denotes other
T11991 9336-9341 NNP denotes TGF-β
T11992 9342-9348 NN denotes family
T11993 9349-9356 NNS denotes members
T11994 9356-9357 , denotes ,
T11995 9358-9367 VBG denotes including
T11996 9368-9374 NNP denotes TGF-β1
T11997 9375-9378 CC denotes and
T11998 9379-9384 NNP denotes BMP-4
T11999 9385-9386 NNP denotes [
T12000 9386-9388 CD denotes 50
T12001 9388-9389 NNP denotes ]
T12002 9389-9390 , denotes ,
T12003 9391-9401 VBG denotes indicating
T12004 9402-9406 IN denotes that
T12005 9407-9415 JJ denotes cellular
T12006 9416-9423 NN denotes context
T12007 9424-9426 IN denotes of
T12008 9427-9430 DT denotes the
T12009 9431-9434 NN denotes BMP
T12010 9435-9441 NN denotes target
T12011 9442-9446 NN denotes cell
T12012 9447-9452 MD denotes might
T12013 9453-9459 VB denotes define
T12014 9460-9463 DT denotes the
T12015 9464-9471 JJ denotes various
T12016 9472-9480 JJ denotes observed
T12017 9481-9488 NNS denotes effects
T12018 9488-9489 . denotes .
T12019 9490-9492 IN denotes In
T12020 9493-9501 NN denotes contrast
T12021 9502-9504 TO denotes to
T12022 9505-9508 DT denotes the
T12023 9509-9521 NN denotes upregulation
T12024 9522-9524 IN denotes of
T12025 9525-9530 NNP denotes BMP-6
T12026 9531-9541 NN denotes transcript
T12027 9542-9544 IN denotes in
T12028 9545-9546 NNP denotes B
T12029 9547-9552 NNS denotes cells
T12030 9552-9553 , denotes ,
T12031 9554-9556 PRP denotes we
T12032 9557-9561 VBD denotes were
T12033 9562-9565 RB denotes not
T12034 9566-9570 JJ denotes able
T12035 9571-9573 TO denotes to
T12036 9574-9580 VB denotes detect
T12037 9581-9586 NNP denotes BMP-6
T12038 9587-9598 NNS denotes transcripts
T12039 9599-9601 IN denotes in
T12040 9602-9607 JJ denotes human
T12041 9608-9618 JJ denotes peripheral
T12042 9619-9624 NN denotes blood
T12043 9625-9628 NNP denotes CD4
T12044 9628-9629 CD denotes +
T12045 9630-9632 CC denotes or
T12046 9633-9636 CD denotes CD8
T12047 9636-9637 CD denotes +
T12048 9638-9639 NNP denotes T
T12049 9640-9645 NNS denotes cells
T12050 9646-9647 -LRB- denotes (
T12051 9647-9654 VBG denotes resting
T12052 9655-9657 CC denotes or
T12053 9658-9668 VBN denotes stimulated
T12054 9669-9673 IN denotes with
T12055 9674-9682 JJ denotes anti-CD3
T12056 9683-9686 CC denotes and
T12057 9687-9696 JJ denotes anti-CD28
T12058 9696-9697 : denotes ;
T12059 9698-9702 NNS denotes data
T12060 9703-9706 RB denotes not
T12061 9707-9712 VBN denotes shown
T12062 9712-9713 -RRB- denotes )
T12063 9713-9714 , denotes ,
T12064 9715-9725 JJ denotes consistent
T12065 9726-9730 IN denotes with
T12066 9731-9734 DT denotes the
T12067 9735-9743 NNS denotes findings
T12068 9744-9746 IN denotes in
T12069 9747-9748 NNP denotes T
T12070 9749-9753 NN denotes cell
T12071 9754-9759 NNS denotes lines
T12072 9760-9761 NNP denotes [
T12073 9761-9763 CD denotes 20
T12074 9763-9764 NNP denotes ]
T12075 9765-9768 CC denotes and
T12076 9769-9770 NNP denotes T
T12077 9771-9776 NNS denotes cells
T12078 9777-9779 IN denotes in
T12079 9780-9784 NNS denotes mice
T12080 9785-9786 NNP denotes [
T12081 9786-9788 CD denotes 43
T12082 9788-9789 NNP denotes ]
T12083 9789-9790 . denotes .
T12084 9791-9796 JJ denotes Other
T12085 9797-9806 JJ denotes potential
T12086 9807-9812 NN denotes BMP-6
T12087 9813-9820 NNS denotes sources
T12088 9821-9824 IN denotes for
T12089 9825-9831 JJ denotes mature
T12090 9832-9833 NNP denotes B
T12091 9834-9839 NNS denotes cells
T12092 9840-9842 IN denotes in
T12093 9843-9847 NN denotes vivo
T12094 9848-9853 MD denotes might
T12095 9854-9856 VB denotes be
T12096 9857-9862 JJ denotes other
T12097 9863-9868 NNS denotes cells
T12098 9869-9871 IN denotes of
T12099 9872-9875 DT denotes the
T12100 9876-9882 JJ denotes immune
T12101 9883-9889 NN denotes system
T12119 9993-9996 DT denotes the
T12120 9997-10002 JJ denotes human
T12121 10003-10007 NN denotes bone
T12122 10008-10011 CC denotes and
T12123 10012-10016 NN denotes bone
T12124 10017-10023 NN denotes marrow
T12125 10024-10030 NN denotes stroma
T12126 10031-10032 NNP denotes [
T12127 10032-10036 CD denotes 51,8
T12128 10036-10037 NNP denotes ]
T12129 10037-10038 . denotes .
T12130 10039-10050 RB denotes Furthermore
T12131 10050-10051 , denotes ,
T12132 10052-10054 PRP denotes it
T12133 10055-10057 VBZ denotes is
T12134 10058-10068 JJ denotes noteworthy
T12135 10069-10073 IN denotes that
T12136 10074-10079 JJ denotes human
T12137 10080-10089 JJ denotes umbilical
T12138 10090-10094 NN denotes vein
T12139 10095-10106 JJ denotes endothelial
T12140 10107-10112 NNS denotes cells
T12141 10113-10114 -LRB- denotes (
T12142 10114-10119 NNP denotes HUVEC
T12143 10119-10120 -RRB- denotes )
T12144 10121-10127 RB denotes highly
T12145 10128-10135 JJ denotes express
T12146 10136-10141 NNP denotes BMP-6
T12147 10142-10146 NNP denotes mRNA
T12148 10147-10148 NNP denotes [
T12149 10148-10150 CD denotes 52
T12150 10150-10151 NNP denotes ]
T12151 10151-10152 , denotes ,
T12152 10153-10156 CC denotes and
T12153 10157-10165 JJ denotes vascular
T12154 10166-10177 NN denotes endothelium
T12155 10178-10181 VBZ denotes has
T12156 10182-10186 VBN denotes been
T12157 10187-10195 VBN denotes reported
T12158 10196-10198 TO denotes to
T12159 10199-10206 VB denotes produce
T12160 10207-10212 NNP denotes BMP-6
T12161 10213-10214 NNP denotes [
T12162 10214-10216 CD denotes 53
T12163 10216-10217 NNP denotes ]
T12164 10217-10218 . denotes .
T12165 10219-10224 DT denotes These
T12166 10225-10232 NNS denotes studies
T12167 10233-10238 MD denotes might
T12168 10239-10244 VB denotes imply
T12169 10245-10246 DT denotes a
T12170 10247-10251 NN denotes role
T12171 10252-10255 IN denotes for
T12172 10256-10261 NNP denotes BMP-6
T12173 10262-10264 IN denotes in
T12174 10265-10281 JJ denotes transendothelial
T12175 10282-10291 NN denotes migration
T12176 10292-10294 IN denotes of
T12177 10295-10296 NNP denotes B
T12178 10297-10302 NNS denotes cells
T12179 10302-10303 . denotes .
T12180 10304-10309 CD denotes BMP-6
T12181 10310-10314 NNP denotes mRNA
T12182 10315-10318 VBZ denotes has
T12183 10319-10323 VBN denotes been
T12184 10324-10336 VBN denotes demonstrated
T12185 10337-10339 IN denotes in
T12186 10340-10346 NN denotes murine
T12187 10347-10357 NN denotes macrophage
T12188 10358-10362 NN denotes cell
T12189 10363-10368 NNS denotes lines
T12190 10368-10369 , denotes ,
T12191 10370-10373 CC denotes but
T12192 10374-10377 RB denotes not
T12193 10378-10380 IN denotes in
T12194 10381-10387 NNS denotes humans
T12195 10388-10389 NNP denotes [
T12196 10389-10391 CD denotes 54
T12197 10391-10392 NNP denotes ]
T12198 10392-10393 . denotes .
T12199 10394-10396 IN denotes In
T12200 10397-10407 NN denotes accordance
T12201 10408-10412 IN denotes with
T12202 10413-10418 DT denotes these
T12203 10419-10427 NNS denotes findings
T12204 10427-10428 , denotes ,
T12205 10429-10434 JJ denotes other
T12206 10435-10440 JJ denotes human
T12207 10441-10445 NN denotes cell
T12208 10446-10451 NNS denotes lines
T12209 10452-10454 IN denotes of
T12210 10455-10465 NN denotes neutrophil
T12211 10466-10469 CC denotes and
T12212 10470-10479 JJ denotes monocytic
T12213 10480-10486 NN denotes origin
T12214 10487-10491 VBP denotes have
T12215 10492-10496 VBN denotes been
T12216 10497-10506 VBN denotes described
T12217 10507-10509 TO denotes to
T12218 10510-10512 VB denotes be
T12219 10513-10521 JJ denotes negative
T12220 10522-10525 IN denotes for
T12221 10526-10529 DT denotes the
T12222 10530-10535 NNP denotes BMP-6
T12223 10536-10546 NN denotes transcript
T12224 10547-10548 NNP denotes [
T12225 10548-10550 CD denotes 20
T12226 10550-10551 NNP denotes ]
T12227 10551-10552 . denotes .
T12228 10553-10555 TO denotes To
T12229 10556-10559 PRP$ denotes our
T12230 10560-10569 NN denotes knowledge
T12231 10569-10570 , denotes ,
T12232 10571-10576 EX denotes there
T12233 10577-10579 VBZ denotes is
T12234 10580-10589 RB denotes currently
T12235 10590-10592 DT denotes no
T12236 10593-10599 NN denotes report
T12237 10600-10605 IN denotes about
T12238 10606-10611 NN denotes BMP-6
T12239 10612-10622 NN denotes production
T12240 10623-10625 IN denotes of
T12241 10626-10631 JJ denotes human
T12242 10632-10641 JJ denotes dendritic
T12243 10642-10647 NNS denotes cells
T12244 10647-10648 . denotes .
T11547 6829-6833 NN denotes role
T11535 6779-6781 CD denotes 35
T11536 6781-6782 NNP denotes ]
T11537 6782-6783 . denotes .
T11538 6784-6792 RB denotes Moreover
T11539 6792-6793 , denotes ,
T11540 6794-6799 NNP denotes BMP-6
T11541 6800-6803 VBZ denotes has
T11542 6804-6808 VBN denotes been
T11543 6809-6818 VBN denotes suggested
T11544 6819-6821 TO denotes to
T11545 6822-6826 VB denotes play
T11546 6827-6828 DT denotes a
T11548 6834-6836 IN denotes in
T11549 6837-6847 JJ denotes rheumatoid
T11550 6848-6857 NNS denotes arthritis
T11551 6858-6859 -LRB- denotes (
T11552 6859-6861 NNP denotes RA
T11553 6861-6862 -RRB- denotes )
T11554 6863-6864 NNP denotes [
T11711 7715-7716 , denotes ,
T11712 7717-7719 DT denotes an
T11713 7720-7729 NN denotes autocrine
T11714 7730-7735 NN denotes BMP-6
T11715 7736-7740 NN denotes loop
T11716 7741-7744 VBZ denotes has
T11717 7745-7749 VBN denotes been
T11718 7750-7758 VBN denotes reported
T11719 7759-7761 IN denotes by
T11720 7762-7768 NNS denotes others
T11721 7769-7771 IN denotes in
T11722 7772-7784 NNS denotes chondrocytes
T11723 7785-7788 CC denotes and
T11724 7789-7791 IN denotes in
T11725 7792-7795 DT denotes the
T11726 7796-7803 NN denotes ovarium
T11727 7804-7805 NNP denotes [
T11728 7805-7813 CD denotes 46,19,18
T11729 7813-7814 NNP denotes ]
T11730 7814-7815 . denotes .
T11731 7816-7825 RB denotes Therefore
T11732 7825-7826 , denotes ,
T11733 7827-7829 PRP denotes we
T11734 7830-7836 VBD denotes wanted
T11735 7837-7839 TO denotes to
T11736 7840-7847 VB denotes explore
T11737 7848-7851 DT denotes the
T11738 7852-7863 NN denotes possibility
T11739 7864-7867 IN denotes for
T11740 7868-7870 DT denotes an
T11741 7871-7880 NN denotes autocrine
T12102 9890-9892 CC denotes or
T12103 9893-9899 NN denotes tissue
T12104 9900-9904 IN denotes with
T12105 9905-9912 NN denotes contact
T12106 9913-9915 TO denotes to
T12107 9916-9919 DT denotes the
T12108 9920-9933 JJ denotes hematopoietic
T12109 9934-9940 NN denotes system
T12110 9940-9941 . denotes .
T12111 9942-9945 CD denotes One
T12112 9946-9950 RB denotes well
T12113 9951-9961 VBN denotes recognized
T12114 9962-9968 NN denotes source
T12115 9969-9972 IN denotes for
T12116 9973-9978 NN denotes BMP-6
T12117 9979-9989 NN denotes production
T12118 9990-9992 VBZ denotes is
R7899 T10336 T10338 amod hematopoietic,cells
R7900 T10324 T10325 amod Recent,studies
R7901 T10325 T10327 nsubj studies,demonstrated
R7902 T10326 T10327 aux have,demonstrated
R7903 T10327 T10366 ccomp demonstrated,reported
R7904 T10328 T10330 det an,role
R7905 T10329 T10330 amod important,role
R7906 T10330 T10327 dobj role,demonstrated
R7907 T10331 T10330 prep for,role
R7908 T10332 T10334 compound BMP,members
R7909 T10333 T10334 compound superfamily,members
R7910 T10334 T10331 pobj members,for
R7911 T10335 T10330 prep in,role
R7912 T10337 T10338 compound stem,cells
R7913 T10338 T10335 pobj cells,in
R7914 T10383 T10384 compound B,cells
R7915 T10339 T10330 punct ",",role
R7916 T10384 T10378 pobj cells,in
R7917 T10385 T10371 punct .,demonstrated
R7918 T10386 T10389 advmod Additionally,induced
R7919 T10340 T10341 amod early,thymocytes
R7920 T10387 T10389 punct ",",induced
R7921 T10388 T10389 nsubj BMP-6,induced
R7922 T10389 T10389 ROOT induced,induced
R7923 T10341 T10344 nmod thymocytes,]
R7924 T10390 T10391 compound cell,death
R7925 T10391 T10389 dobj death,induced
R7926 T10392 T10389 prep in,induced
R7927 T10342 T10344 nmod [,]
R7928 T10393 T10396 compound CD27,B
R7929 T10394 T10396 compound +,B
R7930 T10395 T10396 compound memory,B
R7931 T10343 T10344 nummod "6,7",]
R7932 T10396 T10397 compound B,cells
R7933 T10397 T10392 pobj cells,in
R7934 T10398 T10400 advmod as,as
R7935 T10344 T10347 nmod ],malignancies
R7936 T10399 T10400 advmod well,as
R7937 T10400 T10392 cc as,in
R7938 T10401 T10392 conj in,in
R7939 T10345 T10344 cc and,]
R7940 T10402 T10406 det a,line
R7941 T10403 T10406 compound Burkitt,line
R7942 T10404 T10405 compound lymphoma,cell
R7943 T10346 T10344 conj B-cell,]
R7944 T10405 T10406 compound cell,line
R7945 T10406 T10401 pobj line,in
R7946 T10347 T10366 nsubj malignancies,reported
R7947 T10407 T10406 punct (,line
R7948 T10408 T10406 appos Ramos,line
R7949 T10409 T10406 punct ),line
R7950 T10348 T10350 compound [,]
R7951 T10410 T10389 punct .,induced
R7952 T10411 T10414 advmod Importantly,induced
R7953 T10349 T10350 compound "8,11,12",]
R7954 T10412 T10414 punct ",",induced
R7955 T10413 T10414 nsubj BMP-6,induced
R7956 T10414 T10414 ROOT induced,induced
R7957 T10415 T10419 det a,increase
R7958 T10416 T10419 amod rapid,increase
R7959 T10417 T10416 cc and,rapid
R7960 T10418 T10416 conj marked,rapid
R7961 T10350 T10347 dobj ],malignancies
R7962 T10419 T10414 dobj increase,induced
R7963 T10420 T10419 prep in,increase
R7964 T10421 T10424 quantmod Smad-1,phosphorylation
R7965 T10351 T10347 punct ",",malignancies
R7966 T10422 T10423 compound /,5/8
R7967 T10423 T10424 nummod 5/8,phosphorylation
R7968 T10352 T10347 cc but,malignancies
R7969 T10353 T10354 det a,role
R7970 T10424 T10420 pobj phosphorylation,in
R7971 T10354 T10347 conj role,malignancies
R7972 T10425 T10414 punct .,induced
R7973 T10426 T10430 advmod Furthermore,induced
R7974 T10427 T10430 punct ",",induced
R7975 T10355 T10354 prep for,role
R7976 T10428 T10429 det the,BMP-6
R7977 T10429 T10430 nsubj BMP-6,induced
R7978 T10356 T10355 pobj BMPs,for
R7979 T10430 T10430 ROOT induced,induced
R7980 T10431 T10432 compound Smad,phosphorylation
R7981 T10432 T10434 nsubjpass phosphorylation,followed
R7982 T10357 T10356 prep in,BMPs
R7983 T10433 T10434 auxpass was,followed
R7984 T10434 T10430 advcl followed,induced
R7985 T10435 T10434 agent by,followed
R7986 T10358 T10361 amod normal,cells
R7987 T10436 T10438 det a,upregulation
R7988 T10437 T10438 amod selective,upregulation
R7989 T10438 T10435 pobj upregulation,by
R7990 T10359 T10361 amod human,cells
R7991 T10439 T10438 prep of,upregulation
R7992 T10440 T10441 compound Id1,mRNA
R7993 T10441 T10439 pobj mRNA,of
R7994 T10442 T10441 cc and,mRNA
R7995 T10360 T10361 compound B,cells
R7996 T10361 T10357 pobj cells,in
R7997 T10443 T10445 amod subsequent,protein
R7998 T10444 T10445 amod Id1,protein
R7999 T10362 T10366 aux has,reported
R8000 T10445 T10438 conj protein,upregulation
R8001 T10446 T10434 punct .,followed
R8002 T10363 T10366 advmod previously,reported
R8003 T10447 T10463 prep In,was
R8004 T10448 T10450 det the,study
R8005 T10449 T10450 amod present,study
R8006 T10364 T10366 neg not,reported
R8007 T10450 T10447 pobj study,In
R8008 T10451 T10463 punct ",",was
R8009 T10452 T10455 det the,effect
R8010 T10453 T10455 amod demonstrated,effect
R8011 T10454 T10455 amod antiproliferative,effect
R8012 T10455 T10463 nsubj effect,was
R8013 T10365 T10366 auxpass been,reported
R8014 T10456 T10455 prep of,effect
R8015 T10457 T10456 pobj BMP-6,of
R8016 T10458 T10457 prep in,BMP-6
R8017 T10366 T10366 ROOT reported,reported
R8018 T10459 T10462 amod anti-IgM,cells
R8019 T10460 T10462 amod treated,cells
R8020 T10367 T10366 punct .,reported
R8021 T10461 T10462 compound B,cells
R8022 T10462 T10458 pobj cells,in
R8023 T10463 T10463 ROOT was,was
R8024 T10464 T10463 acomp significant,was
R8025 T10368 T10370 det The,study
R8026 T10465 T10464 cc and,significant
R8027 T10466 T10464 conj dose-dependent,significant
R8028 T10467 T10463 punct .,was
R8029 T10468 T10478 advmod Importantly,neutralized
R8030 T10369 T10370 amod present,study
R8031 T10469 T10478 punct ",",neutralized
R8032 T10470 T10472 det the,effect
R8033 T10471 T10472 amod anti-proliferative,effect
R8034 T10370 T10371 nsubj study,demonstrated
R8035 T10472 T10478 nsubjpass effect,neutralized
R8036 T10473 T10472 prep of,effect
R8037 T10371 T10371 ROOT demonstrated,demonstrated
R8038 T10474 T10473 pobj BMP-6,of
R8039 T10475 T10478 aux could,neutralized
R8040 T10476 T10478 auxpass be,neutralized
R8041 T10372 T10375 det a,effect
R8042 T10477 T10478 advmod completely,neutralized
R8043 T10478 T10478 ROOT neutralized,neutralized
R8044 T10373 T10375 amod significant,effect
R8045 T10374 T10375 amod antiproliferative,effect
R8046 T10375 T10371 dobj effect,demonstrated
R8047 T10479 T10478 agent by,neutralized
R8048 T10376 T10375 prep of,effect
R8049 T10480 T10481 det the,use
R8050 T10481 T10479 pobj use,by
R8051 T10377 T10376 pobj BMP-6,of
R8052 T10482 T10481 prep of,use
R8053 T10483 T10485 det a,inhibitor
R8054 T10484 T10485 amod natural,inhibitor
R8055 T10378 T10377 prep in,BMP-6
R8056 T10485 T10482 pobj inhibitor,of
R8057 T10486 T10481 punct ",",use
R8058 T10379 T10380 amod peripheral,blood
R8059 T10487 T10481 appos Noggin,use
R8060 T10488 T10478 punct .,neutralized
R8061 T10489 T10490 nsubj This,is
R8062 T10490 T10490 ROOT is,is
R8063 T10491 T10490 prep in,is
R8064 T10380 T10384 compound blood,cells
R8065 T10492 T10491 pobj line,in
R8066 T10493 T10492 prep with,line
R8067 T10494 T10493 pobj others,with
R8068 T10495 T10490 punct ",",is
R8069 T10381 T10383 compound CD19,B
R8070 T10496 T10490 advcl showing,is
R8071 T10497 T10500 mark that,function
R8072 T10382 T10383 compound +,B
R8073 T10498 T10500 nsubj Noggin,function
R8074 T10499 T10500 aux can,function
R8075 T10500 T10496 ccomp function,showing
R8076 T10541 T10547 punct ",",demonstrated
R8077 T10501 T10500 prep as,function
R8078 T10502 T10504 det a,antagonist
R8079 T10542 T10543 amod bifunctional,effects
R8080 T10543 T10547 nsubj effects,demonstrated
R8081 T10503 T10504 compound BMP-6,antagonist
R8082 T10504 T10501 pobj antagonist,as
R8083 T10505 T10507 compound [,]
R8084 T10544 T10547 aux have,demonstrated
R8085 T10506 T10507 compound "21,22",]
R8086 T10507 T10504 appos ],antagonist
R8087 T10545 T10547 advmod also,demonstrated
R8088 T10508 T10490 punct .,is
R8089 T10509 T10522 prep In,neutralized
R8090 T10546 T10547 auxpass been,demonstrated
R8091 T10510 T10509 pobj addition,In
R8092 T10511 T10522 punct ",",neutralized
R8093 T10512 T10513 det the,combination
R8094 T10547 T10547 ROOT demonstrated,demonstrated
R8095 T10513 T10522 nsubj combination,neutralized
R8096 T10514 T10513 prep of,combination
R8097 T10548 T10547 prep for,demonstrated
R8098 T10515 T10520 amod soluble,proteins
R8099 T10516 T10519 nmod BMP-RIB-Fc,fusion
R8100 T10517 T10516 cc and,BMP-RIB-Fc
R8101 T10549 T10548 pobj BMPs,for
R8102 T10518 T10516 conj BMP-RII-Fc,BMP-RIB-Fc
R8103 T10519 T10520 compound fusion,proteins
R8104 T10520 T10514 pobj proteins,of
R8105 T10550 T10547 punct .,demonstrated
R8106 T10521 T10522 advmod also,neutralized
R8107 T10522 T10522 ROOT neutralized,neutralized
R8108 T10523 T10525 det the,effect
R8109 T10551 T10558 mark Whereas,shown
R8110 T10524 T10525 amod anti-proliferative,effect
R8111 T10525 T10522 dobj effect,neutralized
R8112 T10526 T10525 prep of,effect
R8113 T10527 T10526 pobj BMP-6,of
R8114 T10528 T10522 prep in,neutralized
R8115 T10552 T10558 nsubjpass several,shown
R8116 T10529 T10531 amod human,cells
R8117 T10530 T10531 compound B,cells
R8118 T10553 T10552 prep of,several
R8119 T10554 T10555 det the,BMPs
R8120 T10531 T10528 pobj cells,in
R8121 T10555 T10553 pobj BMPs,of
R8122 T10532 T10522 punct .,neutralized
R8123 T10533 T10547 advmod Interestingly,demonstrated
R8124 T10556 T10558 aux have,shown
R8125 T10534 T10547 punct ",",demonstrated
R8126 T10535 T10547 prep as,demonstrated
R8127 T10536 T10535 prep for,as
R8128 T10537 T10540 amod other,members
R8129 T10557 T10558 auxpass been,shown
R8130 T10538 T10540 compound TGF,members
R8131 T10539 T10540 compound family,members
R8132 T10540 T10536 pobj members,for
R8133 T10558 T10591 advcl shown,reported
R8134 T10559 T10560 aux to,promote
R8135 T10560 T10558 xcomp promote,shown
R8136 T10575 T10578 nmod ],cells
R8137 T10576 T10575 cc and,]
R8138 T10561 T10560 dobj proliferation,promote
R8139 T10577 T10575 conj granulosa,]
R8140 T10578 T10591 nsubjpass cells,reported
R8141 T10562 T10560 prep in,promote
R8142 T10579 T10581 nmod [,]
R8143 T10580 T10581 nummod 25,]
R8144 T10563 T10565 amod various,types
R8145 T10581 T10578 dobj ],cells
R8146 T10564 T10565 compound cell,types
R8147 T10565 T10562 pobj types,in
R8148 T10582 T10581 punct ",",]
R8149 T10583 T10584 amod antiproliferative,effects
R8150 T10566 T10565 prep including,types
R8151 T10584 T10581 conj effects,]
R8152 T10585 T10584 cc and,effects
R8153 T10567 T10568 nmod condrocytes,[
R8154 T10586 T10584 conj induction,effects
R8155 T10587 T10586 prep of,induction
R8156 T10588 T10587 pobj apoptosis,of
R8157 T10568 T10570 nmod [,]
R8158 T10589 T10591 aux has,reported
R8159 T10590 T10591 auxpass been,reported
R8160 T10591 T10591 ROOT reported,reported
R8161 T10592 T10591 prep for,reported
R8162 T10593 T10597 nmod B,cells
R8163 T10569 T10570 nummod 23,]
R8164 T10594 T10593 cc and,B
R8165 T10595 T10593 conj T,B
R8166 T10596 T10597 compound lineage,cells
R8167 T10570 T10566 pobj ],including
R8168 T10597 T10592 pobj cells,for
R8169 T10598 T10591 punct .,reported
R8170 T10571 T10570 punct ",",]
R8171 T10599 T10600 amod Similar,effects
R8172 T10600 T10615 nsubjpass effects,demonstrated
R8173 T10601 T10602 mark as,demonstrated
R8174 T10572 T10578 nsubj liver,cells
R8175 T10602 T10600 advcl demonstrated,effects
R8176 T10573 T10575 nmod [,]
R8177 T10603 T10602 prep for,demonstrated
R8178 T10574 T10575 nummod 24,]
R8179 T10604 T10603 pobj BMP-6,for
R8180 T10605 T10604 prep on,BMP-6
R8181 T10639 T10640 auxpass been,reported
R8182 T10606 T10608 amod human,cells
R8183 T10607 T10608 compound B,cells
R8184 T10608 T10605 pobj cells,on
R8185 T10609 T10602 prep in,demonstrated
R8186 T10610 T10612 det the,study
R8187 T10611 T10612 amod present,study
R8188 T10640 T10640 ROOT reported,reported
R8189 T10612 T10609 pobj study,in
R8190 T10613 T10615 punct ",",demonstrated
R8191 T10614 T10615 auxpass were,demonstrated
R8192 T10641 T10642 aux to,induce
R8193 T10615 T10615 ROOT demonstrated,demonstrated
R8194 T10616 T10615 prep for,demonstrated
R8195 T10617 T10616 pobj BMP-2,for
R8196 T10642 T10640 xcomp induce,reported
R8197 T10618 T10617 punct ",",BMP-2
R8198 T10619 T10617 appos 4,BMP-2
R8199 T10643 T10642 dobj apoptosis,induce
R8200 T10620 T10617 punct ",",BMP-2
R8201 T10621 T10617 conj 6,BMP-2
R8202 T10622 T10621 cc and,6
R8203 T10644 T10643 punct ",",apoptosis
R8204 T10623 T10621 conj -7,6
R8205 T10624 T10623 prep in,-7
R8206 T10625 T10627 amod human,cells
R8207 T10645 T10643 prep including,apoptosis
R8208 T10626 T10627 compound myeloma,cells
R8209 T10627 T10624 pobj cells,in
R8210 T10646 T10645 prep in,including
R8211 T10628 T10630 compound [,]
R8212 T10629 T10630 compound 9-11,]
R8213 T10630 T10617 appos ],BMP-2
R8214 T10631 T10615 punct .,demonstrated
R8215 T10632 T10633 amod Other,members
R8216 T10633 T10640 nsubj members,reported
R8217 T10647 T10649 compound mouse,lineage
R8218 T10634 T10633 prep of,members
R8219 T10635 T10636 det the,BMP-family
R8220 T10636 T10634 pobj BMP-family,of
R8221 T10648 T10649 compound B,lineage
R8222 T10637 T10640 aux have,reported
R8223 T10638 T10640 advmod also,reported
R8224 T10649 T10650 compound lineage,cells
R8225 T10650 T10646 pobj cells,in
R8226 T10651 T10653 nmod [,]
R8227 T10652 T10653 nummod 26,]
R8228 T10653 T10645 pobj ],including
R8229 T10671 T10683 mark that,is
R8230 T10672 T10673 det the,role
R8231 T10654 T10640 punct .,reported
R8232 T10673 T10683 nsubj role,is
R8233 T10674 T10673 prep of,role
R8234 T10655 T10658 advmod Additionally,inhibits
R8235 T10675 T10674 pobj BMPs,of
R8236 T10676 T10675 prep in,BMPs
R8237 T10677 T10678 det the,regulation
R8238 T10656 T10658 punct ",",inhibits
R8239 T10678 T10676 pobj regulation,in
R8240 T10679 T10678 prep of,regulation
R8241 T10680 T10679 pobj proliferation,of
R8242 T10657 T10658 nsubj BMP-4,inhibits
R8243 T10658 T10658 ROOT inhibits,inhibits
R8244 T10659 T10661 nmod thymocyte,[
R8245 T10681 T10680 cc and,proliferation
R8246 T10682 T10680 conj apoptosis,proliferation
R8247 T10660 T10661 compound proliferation,[
R8248 T10683 T10670 ccomp is,suggest
R8249 T10684 T10685 advmod highly,cell
R8250 T10685 T10686 compound cell,type
R8251 T10661 T10658 dobj [,inhibits
R8252 T10686 T10687 npadvmod type,dependent
R8253 T10687 T10683 acomp dependent,is
R8254 T10688 T10670 punct .,suggest
R8255 T10689 T10690 aux To,examine
R8256 T10690 T10702 advcl examine,analysed
R8257 T10662 T10663 nummod 6,]
R8258 T10691 T10693 advmod how,exerts
R8259 T10692 T10693 nsubj BMP-6,exerts
R8260 T10693 T10690 ccomp exerts,examine
R8261 T10694 T10696 poss its,effects
R8262 T10695 T10696 amod functional,effects
R8263 T10663 T10661 appos ],[
R8264 T10696 T10693 dobj effects,exerts
R8265 T10697 T10696 prep in,effects
R8266 T10698 T10699 compound B,cells
R8267 T10664 T10658 punct .,inhibits
R8268 T10699 T10697 pobj cells,in
R8269 T10700 T10702 punct ",",analysed
R8270 T10701 T10702 nsubj we,analysed
R8271 T10665 T10670 advcl Taken,suggest
R8272 T10702 T10702 ROOT analysed,analysed
R8273 T10703 T10705 compound BMP,expression
R8274 T10666 T10665 advmod together,Taken
R8275 T10704 T10705 compound receptor,expression
R8276 T10705 T10702 dobj expression,analysed
R8277 T10706 T10705 prep by,expression
R8278 T10667 T10670 punct ",",suggest
R8279 T10707 T10709 amod western,analysis
R8280 T10708 T10709 compound blot,analysis
R8281 T10668 T10669 det these,data
R8282 T10709 T10706 pobj analysis,by
R8283 T10710 T10702 punct .,analysed
R8284 T10711 T10714 amod Human,cells
R8285 T10669 T10670 nsubj data,suggest
R8286 T10712 T10714 amod peripheral,cells
R8287 T10713 T10714 compound B,cells
R8288 T10714 T10716 nsubjpass cells,found
R8289 T10670 T10670 ROOT suggest,suggest
R8290 T10715 T10716 auxpass were,found
R8291 T10716 T10716 ROOT found,found
R8292 T10717 T10718 aux to,express
R8293 T10737 T10723 relcl signal,receptors
R8294 T10718 T10716 advcl express,found
R8295 T10719 T10721 det the,type
R8296 T10720 T10721 compound BMP,type
R8297 T10738 T10737 prep after,signal
R8298 T10721 T10718 dobj type,express
R8299 T10722 T10723 nsubj I,receptors
R8300 T10723 T10721 relcl receptors,type
R8301 T10739 T10738 pobj binding,after
R8302 T10724 T10723 dobj Act-RIA,receptors
R8303 T10725 T10724 cc and,Act-RIA
R8304 T10740 T10739 prep of,binding
R8305 T10726 T10724 conj BMP-RIB,Act-RIA
R8306 T10727 T10726 punct ",",BMP-RIB
R8307 T10728 T10726 cc and,BMP-RIB
R8308 T10729 T10730 det the,type
R8309 T10741 T10742 amod several,BMPs
R8310 T10730 T10726 conj type,BMP-RIB
R8311 T10731 T10732 compound II-receptors,BMP-RII
R8312 T10732 T10724 conj BMP-RII,Act-RIA
R8313 T10733 T10732 cc and,BMP-RII
R8314 T10734 T10732 conj Act-RIIb,BMP-RII
R8315 T10735 T10724 punct ",",Act-RIA
R8316 T10736 T10737 nsubj which,signal
R8317 T10742 T10740 pobj BMPs,of
R8318 T10743 T10742 punct ",",BMPs
R8319 T10744 T10742 prep including,BMPs
R8320 T10745 T10746 compound BMP-6,[
R8321 T10746 T10744 pobj [,including
R8322 T10747 T10748 nummod "16,13",]
R8323 T10748 T10746 appos ],[
R8324 T10834 T10838 nsubjpass BMP-2,shown
R8325 T10835 T10838 aux has,shown
R8326 T10749 T10716 punct .,found
R8327 T10836 T10838 advmod also,shown
R8328 T10837 T10838 auxpass been,shown
R8329 T10750 T10752 aux To,explore
R8330 T10838 T10838 ROOT shown,shown
R8331 T10839 T10840 aux to,induce
R8332 T10840 T10838 xcomp induce,shown
R8333 T10751 T10752 advmod further,explore
R8334 T10841 T10840 dobj phosphorylation,induce
R8335 T10842 T10841 prep of,phosphorylation
R8336 T10752 T10761 advcl explore,is
R8337 T10843 T10846 nummod p38,]
R8338 T10844 T10846 nmod [,]
R8339 T10845 T10846 nummod 29,]
R8340 T10846 T10842 pobj ],of
R8341 T10753 T10754 nsubj BMP-6,induced
R8342 T10847 T10838 punct .,shown
R8343 T10848 T10857 advmod Thus,represent
R8344 T10754 T10761 advcl induced,is
R8345 T10849 T10857 punct ",",represent
R8346 T10850 T10857 nsubj phosphorylation,represent
R8347 T10851 T10850 prep of,phosphorylation
R8348 T10755 T10754 prt signalling,induced
R8349 T10852 T10851 pobj p38,of
R8350 T10853 T10850 punct ",",phosphorylation
R8351 T10854 T10850 conj STAT3,phosphorylation
R8352 T10756 T10755 punct ",",signalling
R8353 T10855 T10854 cc and,STAT3
R8354 T10856 T10854 conj Smad1/5/8,STAT3
R8355 T10757 T10761 nsubj activation,is
R8356 T10857 T10857 ROOT represent,represent
R8357 T10858 T10860 amod important,pathways
R8358 T10859 T10860 amod BMP-signalling,pathways
R8359 T10758 T10757 prep of,activation
R8360 T10860 T10857 dobj pathways,represent
R8361 T10861 T10862 nsubj that,mediated
R8362 T10862 T10860 relcl mediated,pathways
R8363 T10863 T10864 det the,effects
R8364 T10864 T10862 dobj effects,mediated
R8365 T10865 T10864 prep of,effects
R8366 T10759 T10760 amod several,pathways
R8367 T10866 T10865 pobj BMPs,of
R8368 T10867 T10866 cc and,BMPs
R8369 T10868 T10869 advmod even,cross-talk
R8370 T10760 T10758 pobj pathways,of
R8371 T10869 T10862 npadvmod cross-talk,mediated
R8372 T10870 T10869 prep between,cross-talk
R8373 T10871 T10872 det these,pathways
R8374 T10761 T10761 ROOT is,is
R8375 T10872 T10870 pobj pathways,between
R8376 T10873 T10875 aux has,reported
R8377 T10874 T10875 auxpass been,reported
R8378 T10762 T10761 acomp possible,is
R8379 T10875 T10857 conj reported,represent
R8380 T10876 T10878 compound [,]
R8381 T10763 T10761 punct .,is
R8382 T10877 T10878 compound "29,30",]
R8383 T10878 T10875 oprd ],reported
R8384 T10879 T10857 punct .,represent
R8385 T10764 T10767 det The,pathway
R8386 T10880 T10886 prep In,were
R8387 T10881 T10883 det the,study
R8388 T10882 T10883 amod present,study
R8389 T10765 T10767 amod major,pathway
R8390 T10883 T10880 pobj study,In
R8391 T10884 T10886 punct ",",were
R8392 T10885 T10886 nsubj we,were
R8393 T10766 T10767 amod signalling,pathway
R8394 T10886 T10886 ROOT were,were
R8395 T10887 T10886 neg not,were
R8396 T10888 T10886 acomp able,were
R8397 T10767 T10772 nsubj pathway,is
R8398 T10889 T10890 aux to,detect
R8399 T10890 T10888 xcomp detect,able
R8400 T10891 T10892 amod BMP-6-induced,changes
R8401 T10768 T10767 acl known,pathway
R8402 T10892 T10890 dobj changes,detect
R8403 T10893 T10890 prep in,detect
R8404 T10894 T10896 det the,status
R8405 T10895 T10896 compound phosphorylation,status
R8406 T10769 T10768 prep to,known
R8407 T10896 T10893 pobj status,in
R8408 T10897 T10896 prep of,status
R8409 T10770 T10769 pobj date,to
R8410 T10898 T10897 pobj STAT3,of
R8411 T10899 T10898 cc or,STAT3
R8412 T10771 T10767 punct ",",pathway
R8413 T10900 T10898 conj p38,STAT3
R8414 T10901 T10896 prep in,status
R8415 T10902 T10905 amod human,cells
R8416 T10772 T10772 ROOT is,is
R8417 T10903 T10905 amod peripheral,cells
R8418 T10904 T10905 compound B,cells
R8419 T10773 T10772 attr activation,is
R8420 T10905 T10901 pobj cells,in
R8421 T10906 T10886 punct .,were
R8422 T10907 T10917 advmod Instead,revealed
R8423 T10774 T10773 prep of,activation
R8424 T10908 T10917 punct ",",revealed
R8425 T10909 T10913 det a,phosphorylation
R8426 T10775 T10774 pobj R-Smads,of
R8427 T10910 T10913 amod rapid,phosphorylation
R8428 T10911 T10910 cc and,rapid
R8429 T10912 T10910 conj marked,rapid
R8430 T10776 T10778 compound [,]
R8431 T10913 T10917 nsubjpass phosphorylation,revealed
R8432 T10914 T10913 prep of,phosphorylation
R8433 T10915 T10914 pobj Smad1/5/8,of
R8434 T10777 T10778 compound "13,27",]
R8435 T10778 T10773 appos ],activation
R8436 T10916 T10917 auxpass was,revealed
R8437 T10779 T10772 punct .,is
R8438 T10917 T10917 ROOT revealed,revealed
R8439 T10918 T10917 punct .,revealed
R8440 T10780 T10787 prep In,shown
R8441 T10919 T10926 prep In,found
R8442 T10920 T10922 det a,study
R8443 T10921 T10922 amod parallel,study
R8444 T10781 T10782 det that,respect
R8445 T10922 T10919 pobj study,In
R8446 T10923 T10926 punct ",",found
R8447 T10782 T10780 pobj respect,In
R8448 T10924 T10926 nsubj we,found
R8449 T10925 T10926 aux have,found
R8450 T10783 T10787 punct ",",shown
R8451 T10926 T10926 ROOT found,found
R8452 T10927 T10931 mark that,induced
R8453 T10784 T10787 nsubjpass BMPs,shown
R8454 T10928 T10929 amod other,BMPs
R8455 T10929 T10931 nsubj BMPs,induced
R8456 T10785 T10787 aux have,shown
R8457 T10930 T10931 advmod also,induced
R8458 T10786 T10787 auxpass been,shown
R8459 T10787 T10787 ROOT shown,shown
R8460 T10788 T10789 aux to,exert
R8461 T10931 T10926 ccomp induced,found
R8462 T10932 T10931 dobj phosphorylation,induced
R8463 T10933 T10932 prep of,phosphorylation
R8464 T10934 T10933 pobj Smad1/5/8,of
R8465 T10789 T10787 xcomp exert,shown
R8466 T10935 T10932 prep in,phosphorylation
R8467 T10936 T10938 amod peripheral,cells
R8468 T10790 T10791 amod antiproliferative,effects
R8469 T10937 T10938 compound B,cells
R8470 T10938 T10935 pobj cells,in
R8471 T10939 T10942 punct (,shown
R8472 T10791 T10789 dobj effects,exert
R8473 T10940 T10942 nsubjpass data,shown
R8474 T10941 T10942 neg not,shown
R8475 T10942 T10931 parataxis shown,induced
R8476 T10792 T10791 prep in,effects
R8477 T10943 T10942 punct ),shown
R8478 T10944 T10926 punct .,found
R8479 T10793 T10794 compound B,lineage
R8480 T10945 T10948 nsubj We,pursuing
R8481 T10946 T10948 aux are,pursuing
R8482 T10947 T10948 advmod currently,pursuing
R8483 T10794 T10795 compound lineage,cells
R8484 T10948 T10948 ROOT pursuing,pursuing
R8485 T10949 T10950 compound microarray,studies
R8486 T10795 T10792 pobj cells,in
R8487 T10950 T10948 dobj studies,pursuing
R8488 T10951 T10952 aux to,identify
R8489 T10952 T10948 advcl identify,pursuing
R8490 T10796 T10789 prep via,exert
R8491 T10953 T10955 det the,pathways
R8492 T10954 T10955 amod signalling,pathways
R8493 T10955 T10952 dobj pathways,identify
R8494 T10797 T10796 pobj phosphorylation,via
R8495 T10956 T10955 cc and,pathways
R8496 T10957 T10958 compound target,genes
R8497 T10958 T10955 conj genes,pathways
R8498 T10798 T10797 prep of,phosphorylation
R8499 T10959 T10962 nsubjpass that,regulated
R8500 T10960 T10962 auxpass are,regulated
R8501 T10961 T10962 advmod differently,regulated
R8502 T10962 T10955 relcl regulated,pathways
R8503 T10799 T10802 amod R-Smad,]
R8504 T10963 T10962 agent by,regulated
R8505 T10964 T10966 det the,BMPs
R8506 T10800 T10802 compound [,]
R8507 T10965 T10966 amod various,BMPs
R8508 T10966 T10963 pobj BMPs,by
R8509 T10967 T10966 prep in,BMPs
R8510 T10801 T10802 compound "11,28",]
R8511 T10968 T10970 amod human,cells
R8512 T10969 T10970 compound B,cells
R8513 T10970 T10967 pobj cells,in
R8514 T10971 T10948 punct .,pursuing
R8515 T10972 T10978 nsubj Upregulation,is
R8516 T10973 T10972 prep of,Upregulation
R8517 T10802 T10798 pobj ],of
R8518 T10974 T10973 pobj Id1,of
R8519 T10975 T10972 prep via,Upregulation
R8520 T10976 T10977 compound Smad1/5/8,phosphorylation
R8521 T10803 T10787 punct .,shown
R8522 T10977 T10975 pobj phosphorylation,via
R8523 T10978 T10978 ROOT is,is
R8524 T10804 T10809 advmod Furthermore,shown
R8525 T10805 T10809 punct ",",shown
R8526 T10979 T10981 det a,mechanism
R8527 T10980 T10981 amod known,mechanism
R8528 T10806 T10809 nsubjpass BMP-2,shown
R8529 T10981 T10978 attr mechanism,is
R8530 T10982 T10981 prep for,mechanism
R8531 T10807 T10809 aux has,shown
R8532 T10983 T10984 nsubj BMP-6,signalling
R8533 T10984 T10982 pcomp signalling,for
R8534 T10985 T10984 prep in,signalling
R8535 T10808 T10809 auxpass been,shown
R8536 T10986 T10988 amod other,systems
R8537 T10987 T10988 compound cell,systems
R8538 T10988 T10985 pobj systems,in
R8539 T10809 T10809 ROOT shown,shown
R8540 T10989 T10991 compound [,]
R8541 T10990 T10991 compound "31,32",]
R8542 T10991 T10984 dobj ],signalling
R8543 T10810 T10811 aux to,induce
R8544 T10992 T10991 cc and,]
R8545 T10993 T10991 conj regulation,]
R8546 T10811 T10809 xcomp induce,shown
R8547 T10812 T10811 dobj activation,induce
R8548 T10813 T10812 prep of,activation
R8549 T10994 T10993 prep of,regulation
R8550 T10995 T10994 pobj Id-proteins,of
R8551 T10814 T10813 pobj STAT3,of
R8552 T10996 T10997 auxpass is,thought
R8553 T10997 T10978 conj thought,is
R8554 T10815 T10812 prep in,activation
R8555 T10998 T10999 aux to,be
R8556 T10999 T10997 xcomp be,thought
R8557 T11000 T11002 det an,mechanism
R8558 T10816 T10817 compound myeloma,cells
R8559 T11001 T11002 amod important,mechanism
R8560 T11002 T10999 attr mechanism,be
R8561 T11003 T11002 prep for,mechanism
R8562 T10817 T10815 pobj cells,in
R8563 T11004 T11005 compound Smad-signalling,[
R8564 T11005 T11007 nmod [,]
R8565 T11006 T11007 nummod 17,]
R8566 T11007 T11003 pobj ],for
R8567 T11008 T10978 punct .,is
R8568 T11009 T11017 prep In,revealed
R8569 T10818 T10820 nmod [,]
R8570 T11010 T11012 det the,study
R8571 T11011 T11012 amod present,study
R8572 T11012 T11009 pobj study,In
R8573 T10819 T10820 nummod 9,]
R8574 T11013 T11017 punct ",",revealed
R8575 T11014 T11016 amod real-time,experiments
R8576 T10820 T10809 dobj ],shown
R8577 T11015 T11016 compound RT-PCR,experiments
R8578 T11016 T11017 nsubj experiments,revealed
R8579 T11017 T11017 ROOT revealed,revealed
R8580 T10821 T10809 punct .,shown
R8581 T11018 T11021 det a,upregulation
R8582 T11019 T11021 amod specific,upregulation
R8583 T11020 T11021 advmod four-fold,upregulation
R8584 T10822 T10829 advmod However,investigated
R8585 T11021 T11017 dobj upregulation,revealed
R8586 T11022 T11021 prep for,upregulation
R8587 T11023 T11022 pobj Id1,for
R8588 T10823 T10829 punct ",",investigated
R8589 T11024 T11021 prep in,upregulation
R8590 T11025 T11026 compound BMP-6-treated,B
R8591 T11026 T11027 compound B,cells
R8592 T10824 T10829 nsubjpass phosphorylation,investigated
R8593 T11027 T11024 pobj cells,in
R8594 T10825 T10824 prep of,phosphorylation
R8595 T10826 T10825 pobj R-Smad,of
R8596 T10827 T10829 auxpass was,investigated
R8597 T11028 T11017 punct ",",revealed
R8598 T11029 T11035 mark while,remained
R8599 T10828 T10829 neg not,investigated
R8600 T11030 T11031 det the,amount
R8601 T11031 T11035 nsubj amount,remained
R8602 T10829 T10829 ROOT investigated,investigated
R8603 T11032 T11031 prep of,amount
R8604 T11033 T11032 pobj Id2,of
R8605 T11034 T11035 nsubj Id4,remained
R8606 T10830 T10829 prep in,investigated
R8607 T11035 T11017 advcl remained,revealed
R8608 T11036 T11035 acomp unchanged,remained
R8609 T10831 T10832 det that,study
R8610 T11037 T11017 punct .,revealed
R8611 T11038 T11046 prep In,demonstrated
R8612 T11039 T11038 pobj agreement,In
R8613 T11040 T11039 prep with,agreement
R8614 T11041 T11040 pobj this,with
R8615 T11042 T11046 punct ",",demonstrated
R8616 T11043 T11045 amod western,analysis
R8617 T11044 T11045 compound blot,analysis
R8618 T10832 T10830 pobj study,in
R8619 T11045 T11046 nsubj analysis,demonstrated
R8620 T11046 T11046 ROOT demonstrated,demonstrated
R8621 T11047 T11048 det an,upregulation
R8622 T10833 T10829 punct .,investigated
R8623 T11048 T11046 dobj upregulation,demonstrated
R8624 T11049 T11048 prep of,upregulation
R8625 T11050 T11051 amod Id1,protein
R8626 T11051 T11049 pobj protein,of
R8627 T11125 T11123 pobj interest,of
R8628 T11052 T11046 punct ",",demonstrated
R8629 T11053 T11062 mark while,remained
R8630 T11054 T11055 det the,amount
R8631 T11055 T11062 nsubj amount,remained
R8632 T11056 T11055 prep of,amount
R8633 T11126 T11122 punct .,is
R8634 T11057 T11056 pobj Id2,of
R8635 T11127 T11132 prep In,is
R8636 T11058 T11057 cc and,Id2
R8637 T11128 T11129 det that,respect
R8638 T11059 T11057 conj Id3,Id2
R8639 T11060 T11061 compound protein,levels
R8640 T11061 T11062 nsubj levels,remained
R8641 T11129 T11127 pobj respect,In
R8642 T11062 T11046 advcl remained,demonstrated
R8643 T11063 T11062 acomp unchanged,remained
R8644 T11130 T11132 punct ",",is
R8645 T11064 T11046 punct .,demonstrated
R8646 T11065 T11070 advmod Previously,considered
R8647 T11131 T11132 nsubj it,is
R8648 T11066 T11070 punct ",",considered
R8649 T11067 T11070 nsubjpass Id1,considered
R8650 T11068 T11070 aux has,considered
R8651 T11132 T11132 ROOT is,is
R8652 T11069 T11070 auxpass been,considered
R8653 T11070 T11070 ROOT considered,considered
R8654 T11133 T11132 acomp noteworthy,is
R8655 T11071 T11074 neg not,expressed
R8656 T11072 T11074 aux to,expressed
R8657 T11134 T11143 mark that,induces
R8658 T11135 T11136 amod TGF-β,signalling
R8659 T11073 T11074 auxpass be,expressed
R8660 T11074 T11070 xcomp expressed,considered
R8661 T11075 T11074 prep in,expressed
R8662 T11136 T11143 nsubj signalling,induces
R8663 T11076 T11078 amod later,stages
R8664 T11077 T11078 amod developmental,stages
R8665 T11078 T11075 pobj stages,in
R8666 T11079 T11074 prep than,expressed
R8667 T11080 T11081 amod pro-B,cells
R8668 T11081 T11079 pobj cells,than
R8669 T11137 T11136 prep in,signalling
R8670 T11082 T11084 compound [,]
R8671 T11083 T11084 compound "33,34",]
R8672 T11084 T11081 appos ],cells
R8673 T11138 T11142 amod early,cells
R8674 T11085 T11084 punct ",",]
R8675 T11086 T11084 cc and,]
R8676 T11139 T11138 cc and,early
R8677 T11087 T11089 poss its,expression
R8678 T11088 T11089 amod constitutive,expression
R8679 T11089 T11092 nsubjpass expression,reported
R8680 T11140 T11138 conj mature,early
R8681 T11090 T11092 aux has,reported
R8682 T11091 T11092 auxpass been,reported
R8683 T11141 T11142 compound B,cells
R8684 T11092 T11070 conj reported,considered
R8685 T11093 T11094 aux to,impair
R8686 T11094 T11092 xcomp impair,reported
R8687 T11095 T11098 compound mouse,development
R8688 T11142 T11137 pobj cells,in
R8689 T11096 T11098 compound B,development
R8690 T11097 T11098 compound cell,development
R8691 T11098 T11094 dobj development,impair
R8692 T11143 T11132 ccomp induces,is
R8693 T11099 T11101 nmod [,]
R8694 T11100 T11101 nummod 35,]
R8695 T11144 T11145 preconj both,Id2
R8696 T11101 T11098 appos ],development
R8697 T11102 T11092 punct .,reported
R8698 T11103 T11122 advmod Therefore,is
R8699 T11145 T11148 amod Id2,expression
R8700 T11104 T11122 punct ",",is
R8701 T11105 T11106 poss our,demonstration
R8702 T11146 T11145 cc and,Id2
R8703 T11106 T11122 nsubj demonstration,is
R8704 T11107 T11106 prep of,demonstration
R8705 T11108 T11110 det the,upregulation
R8706 T11147 T11145 conj Id3,Id2
R8707 T11109 T11110 amod time-dependent,upregulation
R8708 T11110 T11107 pobj upregulation,of
R8709 T11111 T11110 prep of,upregulation
R8710 T11112 T11113 compound Id1,mRNA
R8711 T11148 T11151 compound expression,]
R8712 T11149 T11151 compound [,]
R8713 T11113 T11111 pobj mRNA,of
R8714 T11150 T11151 compound "36,37",]
R8715 T11114 T11110 cc and,upregulation
R8716 T11115 T11110 conj protein,upregulation
R8717 T11116 T11110 prep in,upregulation
R8718 T11117 T11121 amod mature,cells
R8719 T11118 T11121 amod normal,cells
R8720 T11151 T11143 dobj ],induces
R8721 T11119 T11121 amod human,cells
R8722 T11120 T11121 compound B,cells
R8723 T11121 T11116 pobj cells,in
R8724 T11122 T11122 ROOT is,is
R8725 T11152 T11143 punct ",",induces
R8726 T11123 T11122 prep of,is
R8727 T11124 T11125 amod particular,interest
R8728 T11153 T11143 cc but,induces
R8729 T11154 T11155 neg not,Id1
R8730 T11155 T11143 conj Id1,induces
R8731 T11156 T11159 punct (,shown
R8732 T11222 T11203 punct .,found
R8733 T11157 T11159 nsubjpass data,shown
R8734 T11223 T11228 advmod However,induce
R8735 T11224 T11228 punct ",",induce
R8736 T11158 T11159 neg not,shown
R8737 T11225 T11228 nsubj BMP-6,induce
R8738 T11159 T11155 parataxis shown,Id1
R8739 T11226 T11228 aux did,induce
R8740 T11227 T11228 neg not,induce
R8741 T11228 T11228 ROOT induce,induce
R8742 T11160 T11159 punct ),shown
R8743 T11229 T11230 amod significant,changes
R8744 T11230 T11228 dobj changes,induce
R8745 T11161 T11132 punct .,is
R8746 T11231 T11230 prep in,changes
R8747 T11232 T11234 det the,expression
R8748 T11162 T11166 advmod Interestingly,show
R8749 T11233 T11234 compound protein,expression
R8750 T11234 T11231 pobj expression,in
R8751 T11235 T11234 prep of,expression
R8752 T11163 T11166 punct ",",show
R8753 T11236 T11235 pobj Id2,of
R8754 T11237 T11236 cc and,Id2
R8755 T11238 T11236 conj Id3,Id2
R8756 T11164 T11165 det these,results
R8757 T11239 T11228 punct .,induce
R8758 T11240 T11242 nsubjpass It,believed
R8759 T11241 T11242 auxpass is,believed
R8760 T11165 T11166 nsubj results,show
R8761 T11242 T11242 ROOT believed,believed
R8762 T11243 T11246 mark that,block
R8763 T11244 T11246 advmod Id,block
R8764 T11166 T11166 ROOT show,show
R8765 T11245 T11246 nsubj proteins,block
R8766 T11246 T11242 ccomp block,believed
R8767 T11247 T11246 dobj differentiation,block
R8768 T11248 T11246 cc and,block
R8769 T11249 T11246 conj promote,block
R8770 T11250 T11249 dobj proliferation,promote
R8771 T11167 T11174 mark that,regulate
R8772 T11251 T11249 prep in,promote
R8773 T11252 T11254 amod various,types
R8774 T11168 T11169 amod various,members
R8775 T11253 T11254 compound cell,types
R8776 T11254 T11251 pobj types,in
R8777 T11255 T11257 compound [,]
R8778 T11169 T11174 nsubj members,regulate
R8779 T11256 T11257 compound "39,33",]
R8780 T11257 T11246 npadvmod ],block
R8781 T11258 T11242 punct .,believed
R8782 T11170 T11169 prep of,members
R8783 T11259 T11261 advmod Id,act
R8784 T11260 T11261 nsubj proteins,act
R8785 T11171 T11173 det the,family
R8786 T11261 T11261 ROOT act,act
R8787 T11262 T11261 prep as,act
R8788 T11263 T11264 amod dominant-negative,inhibitors
R8789 T11264 T11262 pobj inhibitors,as
R8790 T11172 T11173 compound TGF-β,family
R8791 T11265 T11264 prep of,inhibitors
R8792 T11266 T11265 pobj E-proteins,of
R8793 T11173 T11170 pobj family,of
R8794 T11267 T11266 cc and,E-proteins
R8795 T11268 T11266 conj Pax5,E-proteins
R8796 T11269 T11261 conj function,act
R8797 T11270 T11269 prep by,function
R8798 T11174 T11166 ccomp regulate,show
R8799 T11271 T11270 pcomp forming,by
R8800 T11272 T11271 dobj dimers,forming
R8801 T11175 T11176 compound Id,proteins
R8802 T11273 T11271 prep with,forming
R8803 T11274 T11275 det these,proteins
R8804 T11176 T11174 dobj proteins,regulate
R8805 T11275 T11273 pobj proteins,with
R8806 T11276 T11271 punct ",",forming
R8807 T11277 T11271 advcl making,forming
R8808 T11177 T11174 advmod differently,regulate
R8809 T11278 T11279 nsubj them,unable
R8810 T11279 T11277 ccomp unable,making
R8811 T11178 T11166 punct .,show
R8812 T11280 T11281 aux to,bind
R8813 T11281 T11279 xcomp bind,unable
R8814 T11282 T11281 dobj DNA,bind
R8815 T11179 T11183 nsubjpass Id2,considered
R8816 T11283 T11261 punct .,act
R8817 T11284 T11287 nsubjpass It,proposed
R8818 T11285 T11287 aux has,proposed
R8819 T11286 T11287 auxpass been,proposed
R8820 T11287 T11287 ROOT proposed,proposed
R8821 T11288 T11299 mark that,have
R8822 T11180 T11179 cc and,Id2
R8823 T11289 T11290 det the,balance
R8824 T11290 T11299 nsubj balance,have
R8825 T11291 T11290 prep among,balance
R8826 T11181 T11179 conj Id3,Id2
R8827 T11292 T11291 pobj E-proteins,among
R8828 T11293 T11292 punct ",",E-proteins
R8829 T11182 T11183 auxpass are,considered
R8830 T11294 T11292 conj Pax5,E-proteins
R8831 T11295 T11294 cc and,Pax5
R8832 T11183 T11183 ROOT considered,considered
R8833 T11296 T11297 compound Id,proteins
R8834 T11184 T11185 aux to,be
R8835 T11297 T11294 conj proteins,Pax5
R8836 T11298 T11299 aux might,have
R8837 T11185 T11183 xcomp be,considered
R8838 T11299 T11287 ccomp have,proposed
R8839 T11300 T11302 det an,role
R8840 T11186 T11188 det the,proteins
R8841 T11301 T11302 amod important,role
R8842 T11302 T11299 dobj role,have
R8843 T11303 T11302 prep in,role
R8844 T11187 T11188 compound Id,proteins
R8845 T11304 T11306 amod activated,cells
R8846 T11305 T11306 compound B,cells
R8847 T11188 T11185 attr proteins,be
R8848 T11306 T11303 pobj cells,in
R8849 T11307 T11309 nmod [,]
R8850 T11189 T11190 advmod mainly,expressed
R8851 T11190 T11188 acl expressed,proteins
R8852 T11308 T11309 nummod 38,]
R8853 T11191 T11190 prep in,expressed
R8854 T11309 T11306 appos ],cells
R8855 T11310 T11287 punct .,proposed
R8856 T11311 T11318 prep In,implicated
R8857 T11192 T11194 amod mature,cells
R8858 T11312 T11313 det that,respect
R8859 T11313 T11311 pobj respect,In
R8860 T11193 T11194 compound B,cells
R8861 T11314 T11318 punct ",",implicated
R8862 T11315 T11318 nsubjpass E-proteins,implicated
R8863 T11316 T11318 aux have,implicated
R8864 T11194 T11191 pobj cells,in
R8865 T11317 T11318 auxpass been,implicated
R8866 T11318 T11318 ROOT implicated,implicated
R8867 T11195 T11197 nmod [,]
R8868 T11196 T11197 nummod 38,]
R8869 T11319 T11318 prep in,implicated
R8870 T11320 T11322 preconj both,promotion
R8871 T11197 T11194 appos ],cells
R8872 T11321 T11322 det the,promotion
R8873 T11322 T11319 pobj promotion,in
R8874 T11323 T11322 cc and,promotion
R8875 T11198 T11183 punct .,considered
R8876 T11324 T11322 conj inhibition,promotion
R8877 T11325 T11324 prep of,inhibition
R8878 T11326 T11327 compound cell,survival
R8879 T11199 T11201 det The,study
R8880 T11327 T11325 pobj survival,of
R8881 T11328 T11327 cc and,survival
R8882 T11200 T11201 amod present,study
R8883 T11329 T11327 conj growth,survival
R8884 T11330 T11322 prep at,promotion
R8885 T11331 T11332 amod different,points
R8886 T11201 T11203 nsubj study,found
R8887 T11332 T11330 pobj points,at
R8888 T11333 T11322 prep in,promotion
R8889 T11202 T11203 advmod also,found
R8890 T11334 T11335 compound lymphocyte,development
R8891 T11335 T11333 pobj development,in
R8892 T11336 T11338 nmod [,]
R8893 T11203 T11203 ROOT found,found
R8894 T11337 T11338 nummod 40,]
R8895 T11338 T11322 appos ],promotion
R8896 T11339 T11318 punct .,implicated
R8897 T11204 T11203 dobj Id2,found
R8898 T11340 T11341 det The,antiproliferative
R8899 T11341 T11344 nsubj antiproliferative,inducing
R8900 T11205 T11204 cc and,Id2
R8901 T11342 T11341 cc and,antiproliferative
R8902 T11343 T11344 npadvmod death,inducing
R8903 T11344 T11357 csubj inducing,is
R8904 T11206 T11207 compound Id3,protein
R8905 T11345 T11344 dobj effect,inducing
R8906 T11346 T11345 prep of,effect
R8907 T11347 T11346 pobj BMP-6,of
R8908 T11207 T11204 conj protein,Id2
R8909 T11348 T11344 prep in,inducing
R8910 T11349 T11350 compound B,cells
R8911 T11350 T11348 pobj cells,in
R8912 T11208 T11203 prep in,found
R8913 T11351 T11344 prep with,inducing
R8914 T11352 T11353 amod concomitant,upregulation
R8915 T11353 T11351 pobj upregulation,with
R8916 T11354 T11353 prep of,upregulation
R8917 T11355 T11356 amod Id1,protein
R8918 T11209 T11210 compound B,cells
R8919 T11356 T11354 pobj protein,of
R8920 T11357 T11357 ROOT is,is
R8921 T11358 T11359 advmod therefore,in
R8922 T11210 T11208 pobj cells,in
R8923 T11359 T11357 prep in,is
R8924 T11360 T11359 pobj line,in
R8925 T11211 T11212 aux to,be
R8926 T11361 T11360 prep with,line
R8927 T11362 T11363 det the,view
R8928 T11363 T11361 pobj view,with
R8929 T11212 T11203 advcl be,found
R8930 T11364 T11368 mark that,required
R8931 T11365 T11368 prep Id,required
R8932 T11366 T11368 nsubjpass proteins,required
R8933 T11213 T11215 advmod more,expressed
R8934 T11367 T11368 auxpass are,required
R8935 T11368 T11363 acl required,view
R8936 T11369 T11368 prep for,required
R8937 T11214 T11215 advmod highly,expressed
R8938 T11370 T11371 det the,induction
R8939 T11371 T11369 pobj induction,for
R8940 T11372 T11371 prep of,induction
R8941 T11215 T11212 acomp expressed,be
R8942 T11373 T11374 compound growth,arrest
R8943 T11374 T11372 pobj arrest,of
R8944 T11216 T11215 prep than,expressed
R8945 T11375 T11374 cc and,arrest
R8946 T11376 T11374 conj apoptosis,arrest
R8947 T11217 T11216 pobj Id1,than
R8948 T11218 T11217 prep in,Id1
R8949 T11377 T11371 prep in,induction
R8950 T11219 T11218 pcomp resting,in
R8951 T11378 T11379 amod B-lymphocyte,progenitors
R8952 T11379 T11377 pobj progenitors,in
R8953 T11220 T11221 compound B,cells
R8954 T11380 T11371 prep by,induction
R8955 T11381 T11382 compound TGF-β,[
R8956 T11382 T11380 pobj [,by
R8957 T11221 T11219 dobj cells,resting
R8958 T11383 T11384 nummod 40,]
R8959 T11384 T11382 appos ],[
R8960 T11385 T11357 punct .,is
R8961 T11416 T11422 nsubjpass members,overexpressed
R8962 T11386 T11391 advmod Furthermore,known
R8963 T11417 T11416 prep of,members
R8964 T11387 T11391 punct ",",known
R8965 T11388 T11391 advmod Id,known
R8966 T11418 T11420 det the,family
R8967 T11389 T11391 nsubjpass proteins,known
R8968 T11390 T11391 auxpass are,known
R8969 T11391 T11391 ROOT known,known
R8970 T11392 T11391 prep as,known
R8971 T11393 T11394 amod important,parts
R8972 T11419 T11420 compound Id,family
R8973 T11394 T11392 pobj parts,as
R8974 T11395 T11394 prep of,parts
R8975 T11396 T11395 pcomp signalling,of
R8976 T11420 T11417 pobj family,of
R8977 T11397 T11396 dobj pathways,signalling
R8978 T11398 T11397 acl involved,pathways
R8979 T11399 T11398 prep in,involved
R8980 T11421 T11422 auxpass are,overexpressed
R8981 T11400 T11399 pobj development,in
R8982 T11401 T11400 punct ",",development
R8983 T11402 T11403 compound cell,cycle
R8984 T11422 T11413 ccomp overexpressed,established
R8985 T11403 T11400 conj cycle,development
R8986 T11404 T11403 cc and,cycle
R8987 T11405 T11406 compound tumorigenesis,[
R8988 T11423 T11422 prep in,overexpressed
R8989 T11406 T11406 ROOT [,[
R8990 T11407 T11408 nummod 32,]
R8991 T11408 T11391 dobj ],known
R8992 T11424 T11425 det a,range
R8993 T11409 T11391 punct .,known
R8994 T11410 T11413 nsubjpass It,established
R8995 T11425 T11423 pobj range,in
R8996 T11411 T11413 auxpass is,established
R8997 T11412 T11413 advmod well,established
R8998 T11413 T11413 ROOT established,established
R8999 T11426 T11425 prep of,range
R9000 T11414 T11422 mark that,overexpressed
R9001 T11415 T11416 amod various,members
R9002 T11427 T11428 amod human,tumours
R9003 T11428 T11426 pobj tumours,of
R9004 T11429 T11428 cc and,tumours
R9005 T11439 T11440 advmod most,widely
R9006 T11430 T11433 advmod generally,appears
R9007 T11440 T11441 advmod widely,overexpressed
R9008 T11441 T11435 attr overexpressed,be
R9009 T11442 T11441 prep in,overexpressed
R9010 T11443 T11444 det a,variety
R9011 T11431 T11433 punct ",",appears
R9012 T11444 T11442 pobj variety,in
R9013 T11432 T11433 nsubj Id1,appears
R9014 T11433 T11413 conj appears,established
R9015 T11445 T11444 prep of,variety
R9016 T11434 T11435 aux to,be
R9017 T11446 T11447 amod human,malignancies
R9018 T11447 T11445 pobj malignancies,of
R9019 T11448 T11450 nmod [,]
R9020 T11449 T11450 nummod 41,]
R9021 T11450 T11444 appos ],variety
R9022 T11435 T11433 xcomp be,appears
R9023 T11451 T11444 punct ",",variety
R9024 T11452 T11444 prep including,variety
R9025 T11453 T11455 amod multiple,[
R9026 T11436 T11438 det the,member
R9027 T11454 T11455 compound myeloma,[
R9028 T11455 T11452 pobj [,including
R9029 T11437 T11438 compound family,member
R9030 T11438 T11441 nsubj member,overexpressed
R9031 T11456 T11457 nummod "42,32",]
R9032 T11514 T11513 pobj Id1,of
R9033 T11457 T11455 acl ],[
R9034 T11458 T11433 punct .,appears
R9035 T11459 T11474 advmod Additionally,be
R9036 T11460 T11474 punct ",",be
R9037 T11515 T11512 prep to,expression
R9038 T11461 T11462 poss our,findings
R9039 T11462 T11474 nsubj findings,be
R9040 T11516 T11515 pobj B-lymphocytes,to
R9041 T11463 T11465 dobj that,activates
R9042 T11464 T11465 nsubj BMP-6,activates
R9043 T11517 T11507 ccomp resulted,is
R9044 T11465 T11462 relcl activates,findings
R9045 T11466 T11468 amod intracellular,pathways
R9046 T11467 T11468 amod signalling,pathways
R9047 T11518 T11517 prep in,resulted
R9048 T11468 T11465 dobj pathways,activates
R9049 T11469 T11468 prep in,pathways
R9050 T11470 T11472 amod human,cells
R9051 T11519 T11522 amod aberrant,development
R9052 T11471 T11472 compound B,cells
R9053 T11472 T11469 pobj cells,in
R9054 T11473 T11474 aux might,be
R9055 T11520 T11521 compound B,cell
R9056 T11474 T11474 ROOT be,be
R9057 T11475 T11474 prep of,be
R9058 T11476 T11478 amod potential,significance
R9059 T11521 T11522 compound cell,development
R9060 T11477 T11478 amod pathophysiological,significance
R9061 T11478 T11475 pobj significance,of
R9062 T11479 T11478 prep in,significance
R9063 T11522 T11518 pobj development,in
R9064 T11480 T11479 pobj lymphoma,in
R9065 T11481 T11480 cc and,lymphoma
R9066 T11523 T11522 punct ",",development
R9067 T11482 T11480 conj inflammation,lymphoma
R9068 T11483 T11474 punct .,be
R9069 T11484 T11486 compound High,mRNA
R9070 T11485 T11486 compound BMP-6,mRNA
R9071 T11486 T11487 compound mRNA,expression
R9072 T11487 T11492 nsubjpass expression,shown
R9073 T11524 T11525 amod massive,apoptosis
R9074 T11488 T11487 prep in,expression
R9075 T11489 T11488 pobj DLBCL,in
R9076 T11490 T11492 aux has,shown
R9077 T11491 T11492 auxpass been,shown
R9078 T11525 T11522 conj apoptosis,development
R9079 T11492 T11492 ROOT shown,shown
R9080 T11493 T11494 aux to,correlate
R9081 T11494 T11492 xcomp correlate,shown
R9082 T11526 T11517 punct ",",resulted
R9083 T11495 T11494 prep to,correlate
R9084 T11496 T11497 amod unfavourable,outcome
R9085 T11497 T11495 pobj outcome,to
R9086 T11527 T11517 cc and,resulted
R9087 T11498 T11500 nmod [,]
R9088 T11499 T11500 nummod 12,]
R9089 T11500 T11495 pobj ],to
R9090 T11528 T11529 amod subsequent,development
R9091 T11501 T11492 punct .,shown
R9092 T11502 T11507 prep In,is
R9093 T11503 T11504 det this,respect
R9094 T11529 T11536 nmod development,]
R9095 T11504 T11502 pobj respect,In
R9096 T11505 T11507 punct ",",is
R9097 T11506 T11507 nsubj it,is
R9098 T11530 T11529 prep of,development
R9099 T11507 T11507 ROOT is,is
R9100 T11508 T11507 prep of,is
R9101 T11509 T11508 pobj interest,of
R9102 T11531 T11532 compound B,cell
R9103 T11510 T11517 dobj that,resulted
R9104 T11511 T11512 amod targeted,expression
R9105 T11512 T11517 nsubj expression,resulted
R9106 T11532 T11533 compound cell,lymphomas
R9107 T11513 T11512 prep of,expression
R9108 T11533 T11530 pobj lymphomas,of
R9109 T11534 T11536 nmod [,]
R9110 T11613 T11609 xcomp elucidate,be
R9111 T11535 T11536 nummod 35,]
R9112 T11536 T11507 npadvmod ],is
R9113 T11614 T11615 det the,role
R9114 T11537 T11507 punct .,is
R9115 T11538 T11543 advmod Moreover,suggested
R9116 T11539 T11543 punct ",",suggested
R9117 T11540 T11543 nsubjpass BMP-6,suggested
R9118 T11541 T11543 aux has,suggested
R9119 T11542 T11543 auxpass been,suggested
R9120 T11615 T11613 dobj role,elucidate
R9121 T11543 T11543 ROOT suggested,suggested
R9122 T11616 T11615 prep of,role
R9123 T11617 T11616 pobj Id-1,of
R9124 T11618 T11617 prep in,Id-1
R9125 T11544 T11545 aux to,play
R9126 T11619 T11621 amod human,cells
R9127 T11545 T11543 xcomp play,suggested
R9128 T11620 T11621 compound B,cells
R9129 T11546 T11547 det a,role
R9130 T11547 T11545 dobj role,play
R9131 T11621 T11618 pobj cells,in
R9132 T11548 T11547 prep in,role
R9133 T11549 T11550 amod rheumatoid,arthritis
R9134 T11550 T11548 pobj arthritis,in
R9135 T11622 T11613 prep by,elucidate
R9136 T11551 T11552 punct (,RA
R9137 T11552 T11550 appos RA,arthritis
R9138 T11623 T11622 pobj selective,by
R9139 T11553 T11543 punct ),suggested
R9140 T11554 T11556 compound [,]
R9141 T11555 T11556 compound "43,44",]
R9142 T11556 T11566 nsubjpass ],found
R9143 T11624 T11623 prt over,selective
R9144 T11557 T11556 cc and,]
R9145 T11558 T11559 amod elevated,levels
R9146 T11559 T11556 conj levels,]
R9147 T11625 T11624 pobj expression,over
R9148 T11560 T11559 prep of,levels
R9149 T11561 T11560 pobj Id1,of
R9150 T11562 T11561 cc and,Id1
R9151 T11626 T11625 cc or,expression
R9152 T11563 T11561 conj Id3,Id1
R9153 T11564 T11566 aux have,found
R9154 T11627 T11625 conj inhibition,expression
R9155 T11565 T11566 auxpass been,found
R9156 T11566 T11566 ROOT found,found
R9157 T11567 T11566 prep in,found
R9158 T11628 T11625 prep of,expression
R9159 T11568 T11569 det the,synovia
R9160 T11569 T11567 pobj synovia,in
R9161 T11570 T11569 prep of,synovia
R9162 T11629 T11631 amod Id-1,expression
R9163 T11571 T11570 pobj RA-patients,of
R9164 T11572 T11574 quantmod [,]
R9165 T11573 T11574 nummod 45,]
R9166 T11630 T11631 compound gene,expression
R9167 T11574 T11569 appos ],synovia
R9168 T11575 T11566 punct .,found
R9169 T11576 T11580 advmod Altogether,point
R9170 T11577 T11580 punct ",",point
R9171 T11578 T11579 det these,results
R9172 T11579 T11580 nsubj results,point
R9173 T11631 T11628 pobj expression,of
R9174 T11580 T11580 ROOT point,point
R9175 T11581 T11580 prep to,point
R9176 T11582 T11584 det an,role
R9177 T11583 T11584 amod important,role
R9178 T11632 T11609 punct .,be
R9179 T11584 T11581 pobj role,to
R9180 T11585 T11584 prep for,role
R9181 T11633 T11643 prep Given,demonstrated
R9182 T11586 T11587 compound Id,proteins
R9183 T11587 T11585 pobj proteins,for
R9184 T11588 T11584 prep in,role
R9185 T11589 T11590 det the,regulation
R9186 T11634 T11635 det the,role
R9187 T11590 T11588 pobj regulation,in
R9188 T11591 T11590 prep of,regulation
R9189 T11592 T11595 amod normal,homeostasis
R9190 T11635 T11633 pobj role,Given
R9191 T11593 T11594 compound B,cell
R9192 T11594 T11595 compound cell,homeostasis
R9193 T11595 T11591 pobj homeostasis,of
R9194 T11596 T11588 cc and,in
R9195 T11636 T11635 prep of,role
R9196 T11597 T11588 conj in,in
R9197 T11598 T11597 pobj diseases,in
R9198 T11637 T11636 pobj BMP-6,of
R9199 T11599 T11598 punct ",",diseases
R9200 T11600 T11604 advmod where,involved
R9201 T11601 T11602 compound B,cells
R9202 T11602 T11604 nsubjpass cells,involved
R9203 T11638 T11635 prep in,role
R9204 T11603 T11604 auxpass are,involved
R9205 T11604 T11598 relcl involved,diseases
R9206 T11605 T11580 punct .,point
R9207 T11606 T11609 nsubj It,be
R9208 T11607 T11609 aux will,be
R9209 T11639 T11642 amod mature,cells
R9210 T11608 T11609 advmod therefore,be
R9211 T11640 T11642 amod human,cells
R9212 T11609 T11609 ROOT be,be
R9213 T11610 T11609 acomp important,be
R9214 T11641 T11642 compound B,cells
R9215 T11611 T11613 aux to,elucidate
R9216 T11612 T11613 advmod further,elucidate
R9217 T11642 T11638 pobj cells,in
R9218 T11643 T11643 ROOT demonstrated,demonstrated
R9219 T11644 T11643 advmod here,demonstrated
R9220 T11645 T11643 punct ",",demonstrated
R9221 T11646 T11664 nsubj identification,contribute
R9222 T11711 T11718 punct ",",reported
R9223 T11647 T11646 prep of,identification
R9224 T11712 T11715 det an,loop
R9225 T11713 T11715 amod autocrine,loop
R9226 T11648 T11649 nsubj BMP-6,producing
R9227 T11714 T11715 compound BMP-6,loop
R9228 T11715 T11718 nsubjpass loop,reported
R9229 T11649 T11647 pcomp producing,of
R9230 T11716 T11718 aux has,reported
R9231 T11717 T11718 auxpass been,reported
R9232 T11718 T11718 ROOT reported,reported
R9233 T11650 T11649 dobj cells,producing
R9234 T11719 T11718 agent by,reported
R9235 T11720 T11719 pobj others,by
R9236 T11721 T11720 prep in,others
R9237 T11651 T11649 prep in,producing
R9238 T11722 T11721 pobj chondrocytes,in
R9239 T11723 T11721 cc and,in
R9240 T11652 T11651 pobj vivo,in
R9241 T11724 T11721 conj in,in
R9242 T11725 T11726 det the,ovarium
R9243 T11726 T11724 pobj ovarium,in
R9244 T11653 T11649 prep with,producing
R9245 T11654 T11653 pobj possibility,with
R9246 T11655 T11654 prep of,possibility
R9247 T11727 T11729 compound [,]
R9248 T11656 T11655 pobj interaction,of
R9249 T11728 T11729 compound "46,19,18",]
R9250 T11729 T11720 appos ],others
R9251 T11657 T11656 prep with,interaction
R9252 T11730 T11718 punct .,reported
R9253 T11731 T11734 advmod Therefore,wanted
R9254 T11658 T11657 pobj naïve,with
R9255 T11732 T11734 punct ",",wanted
R9256 T11733 T11734 nsubj we,wanted
R9257 T11659 T11658 cc and,naïve
R9258 T11734 T11734 ROOT wanted,wanted
R9259 T11735 T11736 aux to,explore
R9260 T11736 T11734 xcomp explore,wanted
R9261 T11660 T11662 compound memory,cells
R9262 T11737 T11738 det the,possibility
R9263 T11738 T11736 dobj possibility,explore
R9264 T11739 T11738 prep for,possibility
R9265 T11661 T11662 compound B,cells
R9266 T11740 T11743 det an,loop
R9267 T11741 T11743 amod autocrine,loop
R9268 T11742 T11743 compound BMP-6,loop
R9269 T11743 T11739 pobj loop,for
R9270 T11744 T11743 prep in,loop
R9271 T11745 T11747 amod human,cells
R9272 T11662 T11658 conj cells,naïve
R9273 T11746 T11747 compound B,cells
R9274 T11747 T11744 pobj cells,in
R9275 T11748 T11734 punct .,wanted
R9276 T11749 T11750 nsubj We,analysed
R9277 T11663 T11664 aux might,contribute
R9278 T11750 T11750 ROOT analysed,analysed
R9279 T11751 T11752 det the,expression
R9280 T11752 T11750 dobj expression,analysed
R9281 T11664 T11643 ccomp contribute,demonstrated
R9282 T11753 T11754 compound BMP-6,mRNA
R9283 T11754 T11752 appos mRNA,expression
R9284 T11755 T11750 prep in,analysed
R9285 T11665 T11664 prep to,contribute
R9286 T11756 T11759 amod peripheral,cells
R9287 T11757 T11758 compound blood,B
R9288 T11758 T11759 compound B,cells
R9289 T11666 T11667 det the,understanding
R9290 T11759 T11755 pobj cells,in
R9291 T11760 T11750 prep by,analysed
R9292 T11761 T11762 amod real-time,PCR
R9293 T11762 T11760 pobj PCR,by
R9294 T11667 T11665 pobj understanding,to
R9295 T11763 T11750 punct ",",analysed
R9296 T11764 T11750 cc and,analysed
R9297 T11668 T11667 prep of,understanding
R9298 T11765 T11750 conj report,analysed
R9299 T11669 T11672 amod mature,biology
R9300 T11766 T11765 advmod here,report
R9301 T11670 T11671 compound B,cell
R9302 T11767 T11768 det the,upregulation
R9303 T11768 T11765 dobj upregulation,report
R9304 T11769 T11768 prep of,upregulation
R9305 T11671 T11672 compound cell,biology
R9306 T11770 T11772 amod endogenous,transcripts
R9307 T11771 T11772 compound BMP-6,transcripts
R9308 T11772 T11769 pobj transcripts,of
R9309 T11672 T11668 pobj biology,of
R9310 T11773 T11768 prep after,upregulation
R9311 T11774 T11773 pobj stimulation,after
R9312 T11775 T11768 prep with,upregulation
R9313 T11673 T11643 punct .,demonstrated
R9314 T11776 T11775 pobj FCS,with
R9315 T11777 T11768 punct ",",upregulation
R9316 T11674 T11676 compound High,mRNA
R9317 T11778 T11779 compound human,AB-serum
R9318 T11779 T11768 conj AB-serum,upregulation
R9319 T11780 T11779 cc and,AB-serum
R9320 T11781 T11785 punct ",",anti-IgM
R9321 T11782 T11783 advmod most,importantly
R9322 T11783 T11785 advmod importantly,anti-IgM
R9323 T11675 T11676 compound BMP-6,mRNA
R9324 T11784 T11785 punct ",",anti-IgM
R9325 T11785 T11779 conj anti-IgM,AB-serum
R9326 T11786 T11785 punct .,anti-IgM
R9327 T11676 T11677 compound mRNA,expression
R9328 T11787 T11796 advmod However,were
R9329 T11788 T11796 punct ",",were
R9330 T11789 T11790 poss our,attempts
R9331 T11790 T11796 nsubj attempts,were
R9332 T11677 T11682 nsubjpass expression,detected
R9333 T11791 T11792 aux to,study
R9334 T11792 T11790 acl study,attempts
R9335 T11793 T11795 compound BMP-6,levels
R9336 T11678 T11677 prep in,expression
R9337 T11794 T11795 compound protein,levels
R9338 T11795 T11792 dobj levels,study
R9339 T11796 T11796 ROOT were,were
R9340 T11679 T11678 pobj DLBCL,in
R9341 T11797 T11796 acomp unsuccessful,were
R9342 T11798 T11796 acomp due,were
R9343 T11799 T11798 prep to,due
R9344 T11680 T11682 aux has,detected
R9345 T11800 T11799 pobj problems,to
R9346 T11801 T11800 prep with,problems
R9347 T11802 T11803 amod unspecific,binding
R9348 T11803 T11801 pobj binding,with
R9349 T11681 T11682 auxpass been,detected
R9350 T11804 T11803 prep of,binding
R9351 T11805 T11807 det the,antibodies
R9352 T11806 T11807 amod anti-BMP-6,antibodies
R9353 T11682 T11682 ROOT detected,detected
R9354 T11807 T11804 pobj antibodies,of
R9355 T11808 T11803 conj tested,binding
R9356 T11809 T11808 punct ",",tested
R9357 T11683 T11682 agent by,detected
R9358 T11684 T11685 compound gene,expression
R9359 T11685 T11683 pobj expression,by
R9360 T11810 T11808 cc and,tested
R9361 T11811 T11801 pobj lack,with
R9362 T11686 T11685 acl profiling,expression
R9363 T11812 T11811 prep of,lack
R9364 T11813 T11814 amod specific,staining
R9365 T11687 T11689 nmod [,]
R9366 T11814 T11812 pobj staining,of
R9367 T11815 T11814 prep in,staining
R9368 T11816 T11817 compound control,cells
R9369 T11817 T11815 pobj cells,in
R9370 T11818 T11817 acl known,cells
R9371 T11688 T11689 nummod 12,]
R9372 T11819 T11820 aux to,express
R9373 T11820 T11818 xcomp express,known
R9374 T11821 T11822 compound BMP-6,mRNA
R9375 T11689 T11686 dobj ],profiling
R9376 T11822 T11820 dobj mRNA,express
R9377 T11823 T11796 punct .,were
R9378 T11690 T11682 punct .,detected
R9379 T11824 T11832 prep In,detected
R9380 T11825 T11824 pobj contrast,In
R9381 T11826 T11832 punct ",",detected
R9382 T11691 T11703 advmod Furthermore,detected
R9383 T11827 T11829 det the,protein
R9384 T11828 T11829 compound recombinant,protein
R9385 T11692 T11703 punct ",",detected
R9386 T11829 T11832 nsubjpass protein,detected
R9387 T11830 T11832 auxpass was,detected
R9388 T11831 T11832 advmod readily,detected
R9389 T11693 T11703 nsubjpass production,detected
R9390 T11832 T11832 ROOT detected,detected
R9391 T11833 T11832 punct .,detected
R9392 T11834 T11841 prep In,detected
R9393 T11694 T11693 prep of,production
R9394 T11835 T11836 det that,respect
R9395 T11836 T11834 pobj respect,In
R9396 T11837 T11841 punct ",",detected
R9397 T11695 T11696 compound BMP-6,transcripts
R9398 T11838 T11839 amod few,investigators
R9399 T11839 T11841 nsubj investigators,detected
R9400 T11840 T11841 aux have,detected
R9401 T11696 T11694 pobj transcripts,of
R9402 T11841 T11841 ROOT detected,detected
R9403 T11842 T11843 compound BMP-6,protein
R9404 T11843 T11841 dobj protein,detected
R9405 T11697 T11693 prep in,production
R9406 T11844 T11843 prep in,protein
R9407 T11698 T11701 amod normal,cells
R9408 T11699 T11701 amod activated,cells
R9409 T11845 T11844 pobj humans,in
R9410 T11846 T11844 punct ",",in
R9411 T11700 T11701 compound B,cells
R9412 T11847 T11848 advmod especially,in
R9413 T11848 T11844 conj in,in
R9414 T11849 T11850 amod non-pathogenic,tissue
R9415 T11701 T11697 pobj cells,in
R9416 T11850 T11848 pobj tissue,in
R9417 T11851 T11841 punct .,detected
R9418 T11852 T11853 det The,possibility
R9419 T11853 T11860 nsubj possibility,is
R9420 T11854 T11853 prep of,possibility
R9421 T11702 T11703 auxpass was,detected
R9422 T11855 T11856 compound BMP-6,production
R9423 T11856 T11854 pobj production,of
R9424 T11703 T11703 ROOT detected,detected
R9425 T11857 T11856 prep in,production
R9426 T11858 T11859 amod human,B-cells
R9427 T11859 T11857 pobj B-cells,in
R9428 T11860 T11860 ROOT is,is
R9429 T11704 T11703 prep in,detected
R9430 T11861 T11860 prep in,is
R9431 T11862 T11861 pobj line,in
R9432 T11705 T11707 det the,study
R9433 T11863 T11862 prep with,line
R9434 T11864 T11866 det a,work
R9435 T11865 T11866 amod recent,work
R9436 T11866 T11863 pobj work,with
R9437 T11706 T11707 amod same,study
R9438 T11867 T11868 nsubj that,reported
R9439 T11868 T11866 relcl reported,work
R9440 T11707 T11704 pobj study,in
R9441 T11869 T11870 det the,production
R9442 T11870 T11868 dobj production,reported
R9443 T11871 T11870 prep of,production
R9444 T11872 T11871 pobj BMP-6,of
R9445 T11708 T11703 punct .,detected
R9446 T11873 T11870 prep in,production
R9447 T11874 T11876 compound mouse,cells
R9448 T11709 T11718 prep Of,reported
R9449 T11875 T11876 compound B,cells
R9450 T11876 T11873 pobj cells,in
R9451 T11877 T11860 punct ",",is
R9452 T11878 T11860 advcl infiltrating,is
R9453 T11710 T11709 pobj note,Of
R9454 T11879 T11881 det the,marrow
R9455 T11880 T11881 compound bone,marrow
R9456 T11881 T11878 dobj marrow,infiltrating
R9457 T11907 T11906 punct .,suggested
R9458 T11882 T11881 prep of,marrow
R9459 T11883 T11882 pobj mice,of
R9460 T11884 T11881 prep with,marrow
R9461 T11885 T11886 amod inflammatory,arthritis
R9462 T11886 T11884 pobj arthritis,with
R9463 T11908 T11909 det The,upregulation
R9464 T11887 T11889 nmod [,]
R9465 T11888 T11889 nummod 43,]
R9466 T11909 T11915 nsubj upregulation,is
R9467 T11889 T11881 appos ],marrow
R9468 T11890 T11860 punct .,is
R9469 T11891 T11906 prep In,suggested
R9470 T11892 T11893 det this,study
R9471 T11893 T11891 pobj study,In
R9472 T11894 T11906 punct ",",suggested
R9473 T11910 T11909 prep of,upregulation
R9474 T11895 T11896 det a,role
R9475 T11896 T11906 nsubjpass role,suggested
R9476 T11897 T11896 prep for,role
R9477 T11911 T11912 det the,BMP-6-transcripts
R9478 T11898 T11897 pobj BMPs,for
R9479 T11899 T11898 prep in,BMPs
R9480 T11900 T11902 det the,process
R9481 T11912 T11910 pobj BMP-6-transcripts,of
R9482 T11901 T11902 amod inflammatoric,process
R9483 T11902 T11899 pobj process,in
R9484 T11903 T11902 prep of,process
R9485 T11913 T11909 prep after,upregulation
R9486 T11904 T11903 pobj arthritis,of
R9487 T11905 T11906 auxpass was,suggested
R9488 T11906 T11906 ROOT suggested,suggested
R9489 T11914 T11915 nsubj IgM-crosslinking,is
R9490 T11915 T11915 ROOT is,is
R9491 T11916 T11915 prep of,is
R9492 T11917 T11918 amod pathophysiologic,interest
R9493 T11918 T11916 pobj interest,of
R9494 T12004 T12013 mark that,define
R9495 T11919 T11921 nmod [,]
R9496 T12005 T12006 amod cellular,context
R9497 T12006 T12013 nsubj context,define
R9498 T11920 T11921 nummod 12,]
R9499 T11921 T11915 attr ],is
R9500 T12007 T12006 prep of,context
R9501 T11922 T11915 punct .,is
R9502 T12008 T12011 det the,cell
R9503 T12009 T12011 compound BMP,cell
R9504 T11923 T11924 det A,loss
R9505 T12010 T12011 compound target,cell
R9506 T12011 T12007 pobj cell,of
R9507 T12012 T12013 aux might,define
R9508 T11924 T11929 nsubjpass loss,suggested
R9509 T12013 T12003 ccomp define,indicating
R9510 T12014 T12017 det the,effects
R9511 T11925 T11924 prep of,loss
R9512 T11926 T11925 pobj TGF-β-responsiveness,of
R9513 T12015 T12017 amod various,effects
R9514 T12016 T12017 amod observed,effects
R9515 T12017 T12013 dobj effects,define
R9516 T11927 T11929 aux has,suggested
R9517 T12018 T11982 punct .,are
R9518 T12019 T12032 prep In,were
R9519 T12020 T12019 pobj contrast,In
R9520 T12021 T12020 prep to,contrast
R9521 T12022 T12023 det the,upregulation
R9522 T11928 T11929 auxpass been,suggested
R9523 T12023 T12021 pobj upregulation,to
R9524 T12024 T12023 prep of,upregulation
R9525 T12025 T12026 compound BMP-6,transcript
R9526 T12026 T12024 pobj transcript,of
R9527 T12027 T12023 prep in,upregulation
R9528 T12028 T12029 compound B,cells
R9529 T11929 T11929 ROOT suggested,suggested
R9530 T12029 T12027 pobj cells,in
R9531 T12030 T12032 punct ",",were
R9532 T12031 T12032 nsubj we,were
R9533 T11930 T11931 aux to,be
R9534 T12032 T12032 ROOT were,were
R9535 T12033 T12032 neg not,were
R9536 T12034 T12032 acomp able,were
R9537 T11931 T11929 xcomp be,suggested
R9538 T12035 T12036 aux to,detect
R9539 T12036 T12034 xcomp detect,able
R9540 T11932 T11934 det a,contribution
R9541 T12037 T12038 compound BMP-6,transcripts
R9542 T12038 T12036 dobj transcripts,detect
R9543 T12039 T12036 prep in,detect
R9544 T11933 T11934 amod critical,contribution
R9545 T12040 T12042 amod human,blood
R9546 T12041 T12042 amod peripheral,blood
R9547 T12042 T12043 compound blood,CD4
R9548 T12043 T12039 pobj CD4,in
R9549 T11934 T11931 attr contribution,be
R9550 T12044 T12043 nummod +,CD4
R9551 T12045 T12043 cc or,CD4
R9552 T12046 T12049 nummod CD8,cells
R9553 T11935 T11934 prep to,contribution
R9554 T12047 T12049 nummod +,cells
R9555 T12048 T12049 compound T,cells
R9556 T12049 T12043 conj cells,CD4
R9557 T11936 T11937 amod malignant,transformation
R9558 T12050 T12051 punct (,resting
R9559 T12051 T12043 acl resting,CD4
R9560 T11937 T11935 pobj transformation,to
R9561 T12052 T12051 cc or,resting
R9562 T12053 T12051 conj stimulated,resting
R9563 T12054 T12053 prep with,stimulated
R9564 T11938 T11940 nmod [,]
R9565 T12055 T12059 amod anti-CD3,data
R9566 T12056 T12055 cc and,anti-CD3
R9567 T12057 T12055 conj anti-CD28,anti-CD3
R9568 T12058 T12059 punct ;,data
R9569 T12059 T12054 pobj data,with
R9570 T12060 T12061 neg not,shown
R9571 T11939 T11940 nummod "47,48",]
R9572 T12061 T12059 acl shown,data
R9573 T12062 T12059 punct ),data
R9574 T12063 T12059 punct ",",data
R9575 T12064 T12059 amod consistent,data
R9576 T11940 T11944 nmod ],mechanisms
R9577 T12065 T12064 prep with,consistent
R9578 T12066 T12067 det the,findings
R9579 T12067 T12065 pobj findings,with
R9580 T11941 T11940 cc and,]
R9581 T12068 T12067 prep in,findings
R9582 T12069 T12070 compound T,cell
R9583 T12070 T12071 compound cell,lines
R9584 T11942 T11944 amod similar,mechanisms
R9585 T12071 T12068 pobj lines,in
R9586 T12072 T12074 nmod [,]
R9587 T11943 T11944 amod oncogenic,mechanisms
R9588 T12073 T12074 nummod 20,]
R9589 T12074 T12077 nmod ],cells
R9590 T12075 T12074 cc and,]
R9591 T11944 T11947 nsubjpass mechanisms,postulated
R9592 T12076 T12074 conj T,]
R9593 T12077 T12067 conj cells,findings
R9594 T12078 T12067 prep in,findings
R9595 T11945 T11947 aux have,postulated
R9596 T12079 T12078 pobj mice,in
R9597 T12080 T12082 nmod [,]
R9598 T12081 T12082 nummod 43,]
R9599 T11946 T11947 auxpass been,postulated
R9600 T11947 T11929 conj postulated,suggested
R9601 T12082 T12067 appos ],findings
R9602 T12083 T12032 punct .,were
R9603 T11948 T11947 prep for,postulated
R9604 T12084 T12087 amod Other,sources
R9605 T12085 T12087 amod potential,sources
R9606 T11949 T11948 pobj BMPs,for
R9607 T11950 T11947 punct .,postulated
R9608 T11951 T11954 nsubj Lines,suggest
R9609 T12086 T12087 compound BMP-6,sources
R9610 T12087 T12095 nsubj sources,be
R9611 T11952 T11951 prep of,Lines
R9612 T12088 T12087 prep for,sources
R9613 T12089 T12091 amod mature,cells
R9614 T12090 T12091 compound B,cells
R9615 T11953 T11952 pobj evidence,of
R9616 T12091 T12088 pobj cells,for
R9617 T12092 T12091 prep in,cells
R9618 T12093 T12092 pobj vivo,in
R9619 T12094 T12095 aux might,be
R9620 T12095 T12095 ROOT be,be
R9621 T11954 T11954 ROOT suggest,suggest
R9622 T12096 T12097 amod other,cells
R9623 T12097 T12095 attr cells,be
R9624 T11955 T11957 nsubj [,]
R9625 T12098 T12097 prep of,cells
R9626 T12099 T12101 det the,system
R9627 T11956 T11957 nummod 49,]
R9628 T12100 T12101 amod immune,system
R9629 T12101 T12098 pobj system,of
R9630 T11957 T11954 dobj ],suggest
R9631 T11958 T11966 mark that,is
R9632 T12102 T12101 cc or,system
R9633 T12103 T12101 conj tissue,system
R9634 T12104 T12103 prep with,tissue
R9635 T11959 T11966 prep at,is
R9636 T12105 T12104 pobj contact,with
R9637 T12106 T12105 prep to,contact
R9638 T11960 T11961 amod early,stages
R9639 T12107 T12109 det the,system
R9640 T12108 T12109 amod hematopoietic,system
R9641 T11961 T11959 pobj stages,at
R9642 T12109 T12106 pobj system,to
R9643 T12110 T12095 punct .,be
R9644 T11962 T11961 prep of,stages
R9645 T11963 T11962 pobj carcinogenesis,of
R9646 T11964 T11966 punct ",",is
R9647 T11965 T11966 nsubj BMP-6,is
R9648 T12111 T12114 nummod One,source
R9649 T12112 T12113 advmod well,recognized
R9650 T12113 T12114 amod recognized,source
R9651 T11966 T11957 relcl is,]
R9652 T12114 T12118 nsubj source,is
R9653 T12115 T12114 prep for,source
R9654 T11967 T11966 neg not,is
R9655 T12116 T12117 compound BMP-6,production
R9656 T12117 T12115 pobj production,for
R9657 T12118 T12118 ROOT is,is
R9658 T11968 T11970 det a,promoter
R9659 T12119 T12121 det the,bone
R9660 T12120 T12121 amod human,bone
R9661 T11969 T11970 compound tumour,promoter
R9662 T12121 T12118 attr bone,is
R9663 T12122 T12121 cc and,bone
R9664 T12123 T12124 compound bone,marrow
R9665 T11970 T11966 attr promoter,is
R9666 T12124 T12125 compound marrow,stroma
R9667 T12125 T12121 conj stroma,bone
R9668 T12126 T12128 compound [,]
R9669 T12127 T12128 compound "51,8",]
R9670 T12128 T12121 appos ],bone
R9671 T11971 T11954 punct ",",suggest
R9672 T12129 T12118 punct .,is
R9673 T12130 T12133 advmod Furthermore,is
R9674 T12131 T12133 punct ",",is
R9675 T12132 T12133 nsubj it,is
R9676 T11972 T11954 cc but,suggest
R9677 T12133 T12133 ROOT is,is
R9678 T12134 T12133 acomp noteworthy,is
R9679 T11973 T11954 conj suppresses,suggest
R9680 T12135 T12145 mark that,express
R9681 T12136 T12138 amod human,vein
R9682 T12137 T12138 amod umbilical,vein
R9683 T11974 T11978 amod benign,outgrowth
R9684 T12138 T12140 nmod vein,cells
R9685 T12139 T12140 amod endothelial,cells
R9686 T12140 T12145 nsubj cells,express
R9687 T11975 T11974 cc and,benign
R9688 T12141 T12140 punct (,cells
R9689 T12142 T12140 appos HUVEC,cells
R9690 T12143 T12140 punct ),cells
R9691 T11976 T11974 conj malignant,benign
R9692 T12144 T12145 advmod highly,express
R9693 T12145 T12133 ccomp express,is
R9694 T12146 T12148 compound BMP-6,[
R9695 T11977 T11978 compound tumour,outgrowth
R9696 T12147 T12148 compound mRNA,[
R9697 T12148 T12145 dobj [,express
R9698 T11978 T11973 dobj outgrowth,suppresses
R9699 T12149 T12150 nummod 52,]
R9700 T12150 T12148 conj ],[
R9701 T12151 T12150 punct ",",]
R9702 T12152 T12150 cc and,]
R9703 T11979 T11954 punct .,suggest
R9704 T12153 T12154 amod vascular,endothelium
R9705 T12154 T12150 conj endothelium,]
R9706 T12155 T12157 aux has,reported
R9707 T11980 T11981 det These,findings
R9708 T12156 T12157 auxpass been,reported
R9709 T12157 T12145 conj reported,express
R9710 T11981 T11982 nsubj findings,are
R9711 T12158 T12159 aux to,produce
R9712 T12159 T12157 xcomp produce,reported
R9713 T12160 T12161 compound BMP-6,[
R9714 T11982 T11982 ROOT are,are
R9715 T12161 T12159 dobj [,produce
R9716 T12162 T12163 nummod 53,]
R9717 T11983 T11982 prep in,are
R9718 T11984 T11985 amod good,agreement
R9719 T12163 T12161 appos ],[
R9720 T11985 T11983 pobj agreement,in
R9721 T12164 T12133 punct .,is
R9722 T11986 T11985 prep with,agreement
R9723 T12165 T12166 det These,studies
R9724 T12166 T12168 nsubj studies,imply
R9725 T12167 T12168 aux might,imply
R9726 T11987 T11988 amod previous,findings
R9727 T12168 T12168 ROOT imply,imply
R9728 T12169 T12170 det a,role
R9729 T12170 T12168 dobj role,imply
R9730 T11988 T11986 pobj findings,with
R9731 T12171 T12170 prep for,role
R9732 T12172 T12171 pobj BMP-6,for
R9733 T11989 T11985 prep for,agreement
R9734 T12173 T12170 prep in,role
R9735 T12174 T12175 amod transendothelial,migration
R9736 T12175 T12173 pobj migration,in
R9737 T11990 T11993 amod other,members
R9738 T12176 T12175 prep of,migration
R9739 T12177 T12178 compound B,cells
R9740 T12178 T12176 pobj cells,of
R9741 T11991 T11993 compound TGF-β,members
R9742 T12179 T12168 punct .,imply
R9743 T12180 T12184 npadvmod BMP-6,demonstrated
R9744 T11992 T11993 compound family,members
R9745 T12181 T12184 nsubjpass mRNA,demonstrated
R9746 T12182 T12184 aux has,demonstrated
R9747 T12183 T12184 auxpass been,demonstrated
R9748 T12184 T12184 ROOT demonstrated,demonstrated
R9749 T11993 T11989 pobj members,for
R9750 T12185 T12184 prep in,demonstrated
R9751 T12186 T12189 compound murine,lines
R9752 T11994 T11993 punct ",",members
R9753 T12187 T12189 compound macrophage,lines
R9754 T12188 T12189 compound cell,lines
R9755 T12189 T12185 pobj lines,in
R9756 T11995 T11993 prep including,members
R9757 T12190 T12184 punct ",",demonstrated
R9758 T12191 T12184 cc but,demonstrated
R9759 T12192 T12193 neg not,in
R9760 T11996 T11995 pobj TGF-β1,including
R9761 T12193 T12184 conj in,demonstrated
R9762 T12194 T12193 pobj humans,in
R9763 T12195 T12197 nmod [,]
R9764 T11997 T11996 cc and,TGF-β1
R9765 T12196 T12197 nummod 54,]
R9766 T12197 T12193 conj ],in
R9767 T12198 T12184 punct .,demonstrated
R9768 T11998 T11999 compound BMP-4,[
R9769 T12199 T12216 prep In,described
R9770 T11999 T11996 conj [,TGF-β1
R9771 T12200 T12199 pobj accordance,In
R9772 T12201 T12200 prep with,accordance
R9773 T12000 T12001 nummod 50,]
R9774 T12202 T12203 det these,findings
R9775 T12203 T12201 pobj findings,with
R9776 T12001 T11996 conj ],TGF-β1
R9777 T12204 T12216 punct ",",described
R9778 T12205 T12208 amod other,lines
R9779 T12206 T12208 amod human,lines
R9780 T12002 T11982 punct ",",are
R9781 T12003 T11982 advcl indicating,are
R9782 T12207 T12208 compound cell,lines
R9783 T12208 T12216 nsubjpass lines,described
R9784 T12209 T12208 prep of,lines
R9786 T12210 T12209 pobj neutrophil,of
R9787 T12211 T12210 cc and,neutrophil
R9788 T12212 T12213 amod monocytic,origin
R9789 T12213 T12210 conj origin,neutrophil
R9790 T12214 T12216 aux have,described
R9791 T12215 T12216 auxpass been,described
R9792 T12216 T12216 ROOT described,described
R9793 T12217 T12218 aux to,be
R9794 T12218 T12216 xcomp be,described
R9795 T12219 T12218 acomp negative,be
R9796 T12220 T12218 prep for,be
R9797 T12221 T12223 det the,transcript
R9798 T12222 T12223 compound BMP-6,transcript
R9799 T12223 T12220 pobj transcript,for
R9800 T12224 T12226 quantmod [,]
R9801 T12225 T12226 nummod 20,]
R9802 T12226 T12218 npadvmod ],be
R9803 T12227 T12216 punct .,described
R9804 T12228 T12233 prep To,is
R9805 T12229 T12230 poss our,knowledge
R9806 T12230 T12228 pobj knowledge,To
R9807 T12231 T12233 punct ",",is
R9808 T12232 T12233 expl there,is
R9809 T12233 T12233 ROOT is,is
R9810 T12234 T12233 advmod currently,is
R9811 T12235 T12236 det no,report
R9812 T12236 T12233 attr report,is
R9813 T12237 T12236 prep about,report
R9814 T12238 T12239 compound BMP-6,production
R9815 T12239 T12237 pobj production,about
R9816 T12240 T12239 prep of,production
R9817 T12241 T12243 amod human,cells
R9818 T12242 T12243 amod dendritic,cells
R9819 T12243 T12240 pobj cells,of
R9820 T12244 T12233 punct .,is

UBERON-AE

Id Subject Object Predicate Lexical cue
T7561 10024-10030 http://purl.obolibrary.org/obo/UBERON_0003891 denotes stroma
T7562 10080-10094 http://purl.obolibrary.org/obo/UBERON_0002066 denotes umbilical vein
T7563 10080-10106 http://purl.obolibrary.org/obo/UBERON_0007777 denotes umbilical vein endothelial
T7564 10090-10094 http://purl.obolibrary.org/obo/UBERON_0001638 denotes vein
T7565 10166-10177 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
T7548 348-353 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T7549 7962-7967 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T7550 9619-9624 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T7551 1104-1107 http://purl.obolibrary.org/obo/UBERON_0002228 denotes RIB
T7552 2256-2259 http://purl.obolibrary.org/obo/UBERON_0002228 denotes RIB
T7553 1442-1447 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
T7554 8096-8101 http://purl.obolibrary.org/obo/UBERON_0001977 denotes serum
T7555 8520-8526 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
T7556 9893-9899 http://purl.obolibrary.org/obo/UBERON_0000479 denotes tissue
T7557 8684-8695 http://purl.obolibrary.org/obo/UBERON_0002371 denotes bone marrow
T7558 10012-10023 http://purl.obolibrary.org/obo/UBERON_0002371 denotes bone marrow
T7559 9876-9889 http://purl.obolibrary.org/obo/UBERON_0002405 denotes immune system
T7560 9920-9940 http://purl.obolibrary.org/obo/UBERON_0002390 denotes hematopoietic system

GO-BP

Id Subject Object Predicate Lexical cue
T7880 397-407 http://purl.obolibrary.org/obo/GO_0008219 denotes cell death
T7881 402-407 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T7882 5668-5673 http://purl.obolibrary.org/obo/GO_0016265 denotes death
T7883 417-423 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T7884 7435-7441 http://purl.obolibrary.org/obo/GO_0007613 denotes memory
T7885 553-568 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T7886 606-621 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T7887 2641-2656 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T7888 2771-2786 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T7889 2869-2884 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T7890 2904-2919 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T7891 3174-3189 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T7892 3270-3285 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T7893 3377-3392 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T7894 3647-3662 http://purl.obolibrary.org/obo/GO_0016310 denotes phosphorylation
T7895 1522-1531 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T7896 1796-1805 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T7897 2002-2011 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T7898 5859-5868 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T7899 6720-6729 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T7900 1522-1531 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T7901 1796-1805 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T7902 2002-2011 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T7903 5859-5868 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T7904 6720-6729 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T7905 1877-1900 http://purl.obolibrary.org/obo/GO_0033080 denotes thymocyte proliferation
T7906 1970-1980 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T7907 3739-3749 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T7908 7034-7044 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T7909 2315-2321 http://purl.obolibrary.org/obo/GO_0023052 denotes signal
T7910 2411-2421 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T7911 2477-2487 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T7912 2972-2982 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T7913 3507-3517 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T7914 3694-3704 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T7915 3814-3824 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T7916 4559-4569 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T7917 5969-5979 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T7918 6372-6382 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T7919 2477-2495 http://purl.obolibrary.org/obo/GO_0007165 denotes signalling pathway
T7920 2972-2991 http://purl.obolibrary.org/obo/GO_0007165 denotes signalling pathways
T7921 3507-3526 http://purl.obolibrary.org/obo/GO_0007165 denotes signalling pathways
T7922 5969-5988 http://purl.obolibrary.org/obo/GO_0007165 denotes signalling pathways
T7923 6372-6391 http://purl.obolibrary.org/obo/GO_0007165 denotes signalling pathways
T7924 2888-2891 http://purl.obolibrary.org/obo/GO_0004707 denotes p38
T7925 2923-2926 http://purl.obolibrary.org/obo/GO_0004707 denotes p38
T7926 3209-3212 http://purl.obolibrary.org/obo/GO_0004707 denotes p38
T7927 2968-2991 http://purl.obolibrary.org/obo/GO_0030513 denotes BMP-signalling pathways
T7928 2968-2991 http://purl.obolibrary.org/obo/GO_0030514 denotes BMP-signalling pathways
T7929 2968-2991 http://purl.obolibrary.org/obo/GO_0030510 denotes BMP-signalling pathways
T7930 2968-2991 http://purl.obolibrary.org/obo/GO_0030509 denotes BMP-signalling pathways
T7931 2972-3005 http://purl.obolibrary.org/obo/GO_0007229 denotes signalling pathways that mediated
T7932 2972-3005 http://purl.obolibrary.org/obo/GO_0019221 denotes signalling pathways that mediated
T7933 2972-3005 http://purl.obolibrary.org/obo/GO_0009755 denotes signalling pathways that mediated
T7934 2972-3005 http://purl.obolibrary.org/obo/GO_0038007 denotes signalling pathways that mediated
T7935 2972-3005 http://purl.obolibrary.org/obo/GO_0038161 denotes signalling pathways that mediated
T7936 2972-3005 http://purl.obolibrary.org/obo/GO_0038166 denotes signalling pathways that mediated
T7937 2972-3005 http://purl.obolibrary.org/obo/GO_0035689 denotes signalling pathways that mediated
T7938 2972-3005 http://purl.obolibrary.org/obo/GO_0070098 denotes signalling pathways that mediated
T7939 2972-3005 http://purl.obolibrary.org/obo/GO_0071847 denotes signalling pathways that mediated
T7940 3507-3537 http://purl.obolibrary.org/obo/GO_0031929 denotes signalling pathways and target
T7941 3863-3865 http://purl.obolibrary.org/obo/GO_0003964 denotes RT
T7942 4345-4361 http://purl.obolibrary.org/obo/GO_0048468 denotes cell development
T7943 6694-6710 http://purl.obolibrary.org/obo/GO_0048468 denotes cell development
T7944 4350-4361 http://purl.obolibrary.org/obo/GO_0032502 denotes development
T7945 5624-5635 http://purl.obolibrary.org/obo/GO_0032502 denotes development
T7946 6001-6012 http://purl.obolibrary.org/obo/GO_0032502 denotes development
T7947 6699-6710 http://purl.obolibrary.org/obo/GO_0032502 denotes development
T7948 6746-6757 http://purl.obolibrary.org/obo/GO_0032502 denotes development
T7949 5583-5589 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T7950 5841-5847 http://purl.obolibrary.org/obo/GO_0040007 denotes growth
T7951 5613-5635 http://purl.obolibrary.org/obo/GO_0030098 denotes lymphocyte development
T7952 5859-5884 http://purl.obolibrary.org/obo/GO_0001783 denotes apoptosis in B-lymphocyte
T7953 5859-5884 http://purl.obolibrary.org/obo/GO_0002901 denotes apoptosis in B-lymphocyte
T7954 6014-6024 http://purl.obolibrary.org/obo/GO_0007049 denotes cell cycle
T7955 6348-6391 http://purl.obolibrary.org/obo/GO_1902533 denotes activates intracellular signalling pathways
T7956 6358-6391 http://purl.obolibrary.org/obo/GO_0030522 denotes intracellular signalling pathways
T7957 6358-6391 http://purl.obolibrary.org/obo/GO_0035556 denotes intracellular signalling pathways
T7958 6358-6391 http://purl.obolibrary.org/obo/GO_1902532 denotes intracellular signalling pathways
T7959 6358-6391 http://purl.obolibrary.org/obo/GO_1902531 denotes intracellular signalling pathways
T7960 6479-6491 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T7961 7062-7073 http://purl.obolibrary.org/obo/GO_0042592 denotes homeostasis
T7962 7256-7271 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T7963 7571-7586 http://purl.obolibrary.org/obo/GO_0010467 denotes gene expression
T7964 9407-9415 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular

GO-MF

Id Subject Object Predicate Lexical cue
T12251 8263-8273 http://purl.obolibrary.org/obo/GO_0003823 denotes antibodies
T12245 2328-2335 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12246 8237-8244 http://purl.obolibrary.org/obo/GO_0005488 denotes binding
T12247 2888-2891 http://purl.obolibrary.org/obo/GO_0004707 denotes p38
T12248 2923-2926 http://purl.obolibrary.org/obo/GO_0004707 denotes p38
T12249 3209-3212 http://purl.obolibrary.org/obo/GO_0004707 denotes p38
T12250 3863-3865 http://purl.obolibrary.org/obo/GO_0003964 denotes RT

GO-CC

Id Subject Object Predicate Lexical cue
T12252 112-117 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12253 215-220 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12254 362-367 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12255 426-431 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12256 798-803 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12257 1209-1214 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12258 1467-1472 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12259 1570-1575 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12260 1630-1635 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12261 1716-1721 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12262 1836-1841 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12263 2099-2104 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12264 2187-2192 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12265 2631-2636 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12266 2751-2756 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12267 3235-3240 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12268 3422-3427 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12269 3606-3611 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12270 3952-3957 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12271 4262-4267 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12272 4481-4486 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12273 4592-4597 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12274 4860-4865 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12275 4926-4931 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12276 4982-4987 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12277 5464-5469 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12278 5704-5709 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12279 6403-6408 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12280 7099-7104 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12281 7199-7204 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12282 7315-7320 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12283 7374-7379 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12284 7444-7449 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12285 7670-7675 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12286 7903-7908 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12287 7970-7975 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12288 8323-8328 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12289 8575-8580 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12290 8660-8665 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12291 9547-9552 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12292 9640-9645 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12293 9771-9776 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12294 9834-9839 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12295 9863-9868 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12296 10107-10112 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12297 10297-10302 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12298 10642-10647 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T12299 6358-6371 http://purl.obolibrary.org/obo/GO_0005622 denotes intracellular
T12300 8263-8273 http://purl.obolibrary.org/obo/GO_0019815 denotes antibodies
T12301 8263-8273 http://purl.obolibrary.org/obo/GO_0042571 denotes antibodies

sentences

Id Subject Object Predicate Lexical cue
T7807 11-254 Sentence denotes Recent studies have demonstrated an important role for BMP superfamily members in hematopoietic stem cells, early thymocytes [6,7] and B-cell malignancies [8,11,12], but a role for BMPs in normal human B cells has previously not been reported.
T7808 255-368 Sentence denotes The present study demonstrated a significant antiproliferative effect of BMP-6 in peripheral blood CD19+ B cells.
T7809 369-483 Sentence denotes Additionally, BMP-6 induced cell death in CD27+ memory B cells as well as in a Burkitt lymphoma cell line (Ramos).
T7810 484-569 Sentence denotes Importantly, BMP-6 induced a rapid and marked increase in Smad-1/5/8 phosphorylation.
T7811 570-702 Sentence denotes Furthermore, the BMP-6 induced Smad phosphorylation was followed by a selective upregulation of Id1 mRNA and subsequent Id1 protein.
T7812 703-839 Sentence denotes In the present study, the demonstrated antiproliferative effect of BMP-6 in anti-IgM treated B cells was significant and dose-dependent.
T7813 840-1059 Sentence denotes Importantly, the anti-proliferative effect of BMP-6 could be completely neutralized by the use of a natural inhibitor, Noggin. This is in line with others, showing that Noggin can function as a BMP-6 antagonist [21,22].
T7814 1060-1215 Sentence denotes In addition, the combination of soluble BMP-RIB-Fc and BMP-RII-Fc fusion proteins also neutralized the anti-proliferative effect of BMP-6 in human B cells.
T7815 1216-1322 Sentence denotes Interestingly, as for other TGF family members, bifunctional effects have also been demonstrated for BMPs.
T7816 1323-1576 Sentence denotes Whereas several of the BMPs have been shown to promote proliferation in various cell types including condrocytes [23], liver [24] and granulosa cells [25], antiproliferative effects and induction of apoptosis has been reported for B and T lineage cells.
T7817 1577-1729 Sentence denotes Similar effects as demonstrated for BMP-6 on human B cells in the present study, were demonstrated for BMP-2, 4, 6 and -7 in human myeloma cells [9-11].
T7818 1730-1847 Sentence denotes Other members of the BMP-family have also been reported to induce apoptosis, including in mouse B lineage cells [26].
T7819 1848-1905 Sentence denotes Additionally, BMP-4 inhibits thymocyte proliferation [6].
T7820 1906-2042 Sentence denotes Taken together, these data suggest that the role of BMPs in the regulation of proliferation and apoptosis is highly cell type dependent.
T7821 2043-2167 Sentence denotes To examine how BMP-6 exerts its functional effects in B cells, we analysed BMP receptor expression by western blot analysis.
T7822 2168-2377 Sentence denotes Human peripheral B cells were found to express the BMP type I receptors Act-RIA and BMP-RIB, and the type II-receptors BMP-RII and Act-RIIb, which signal after binding of several BMPs, including BMP-6 [16,13].
T7823 2378-2466 Sentence denotes To further explore BMP-6 induced signalling, activation of several pathways is possible.
T7824 2467-2544 Sentence denotes The major signalling pathway known to date, is activation of R-Smads [13,27].
T7825 2545-2675 Sentence denotes In that respect, BMPs have been shown to exert antiproliferative effects in B lineage cells via phosphorylation of R-Smad [11,28].
T7826 2676-2761 Sentence denotes Furthermore, BMP-2 has been shown to induce activation of STAT3 in myeloma cells [9].
T7827 2762-2832 Sentence denotes However, phosphorylation of R-Smad was not investigated in that study.
T7828 2833-2897 Sentence denotes BMP-2 has also been shown to induce phosphorylation of p38 [29].
T7829 2898-3095 Sentence denotes Thus, phosphorylation of p38, STAT3 and Smad1/5/8 represent important BMP-signalling pathways that mediated the effects of BMPs and even cross-talk between these pathways has been reported [29,30].
T7830 3096-3241 Sentence denotes In the present study, we were not able to detect BMP-6-induced changes in the phosphorylation status of STAT3 or p38 in human peripheral B cells.
T7831 3242-3312 Sentence denotes Instead, a rapid and marked phosphorylation of Smad1/5/8 was revealed.
T7832 3313-3445 Sentence denotes In a parallel study, we have found that other BMPs also induced phosphorylation of Smad1/5/8 in peripheral B cells (data not shown).
T7833 3446-3612 Sentence denotes We are currently pursuing microarray studies to identify the signalling pathways and target genes that are differently regulated by the various BMPs in human B cells.
T7834 3613-3830 Sentence denotes Upregulation of Id1 via Smad1/5/8 phosphorylation is a known mechanism for BMP-6 signalling in other cell systems [31,32] and regulation of Id-proteins is thought to be an important mechanism for Smad-signalling [17].
T7835 3831-4006 Sentence denotes In the present study, real-time RT-PCR experiments revealed a specific four-fold upregulation for Id1 in BMP-6-treated B cells, while the amount of Id2–Id4 remained unchanged.
T7836 4007-4164 Sentence denotes In agreement with this, western blot analysis demonstrated an upregulation of Id1 protein, while the amount of Id2 and Id3 protein levels remained unchanged.
T7837 4165-4367 Sentence denotes Previously, Id1 has been considered not to be expressed in later developmental stages than pro-B cells [33,34], and its constitutive expression has been reported to impair mouse B cell development [35].
T7838 4368-4513 Sentence denotes Therefore, our demonstration of the time-dependent upregulation of Id1 mRNA and protein in mature normal human B cells is of particular interest.
T7839 4514-4672 Sentence denotes In that respect, it is noteworthy that TGF-β signalling in early and mature B cells induces both Id2 and Id3 expression [36,37], but not Id1 (data not shown).
T7840 4673-4781 Sentence denotes Interestingly, these results show that various members of the TGF-β family regulate Id proteins differently.
T7841 4782-4871 Sentence denotes Id2 and Id3 are considered to be the Id proteins mainly expressed in mature B cells [38].
T7842 4872-4988 Sentence denotes The present study also found Id2 and Id3 protein in B cells to be more highly expressed than Id1 in resting B cells.
T7843 4989-5080 Sentence denotes However, BMP-6 did not induce significant changes in the protein expression of Id2 and Id3.
T7844 5081-5191 Sentence denotes It is believed that Id proteins block differentiation and promote proliferation in various cell types [39,33].
T7845 5192-5342 Sentence denotes Id proteins act as dominant-negative inhibitors of E-proteins and Pax5 function by forming dimers with these proteins, making them unable to bind DNA.
T7846 5343-5475 Sentence denotes It has been proposed that the balance among E-proteins, Pax5 and Id proteins might have an important role in activated B cells [38].
T7847 5476-5641 Sentence denotes In that respect, E-proteins have been implicated in both the promotion and inhibition of cell survival and growth at different points in lymphocyte development [40].
T7848 5642-5911 Sentence denotes The antiproliferative and death inducing effect of BMP-6 in B cells with concomitant upregulation of Id1 protein is therefore in line with the view that Id proteins are required for the induction of growth arrest and apoptosis in B-lymphocyte progenitors by TGF-β [40].
T7849 5912-6048 Sentence denotes Furthermore, Id proteins are known as important parts of signalling pathways involved in development, cell cycle and tumorigenesis [32].
T7850 6049-6309 Sentence denotes It is well established that various members of the Id family are overexpressed in a range of human tumours and generally, Id1 appears to be the family member most widely overexpressed in a variety of human malignancies [41], including multiple myeloma [42,32].
T7851 6310-6492 Sentence denotes Additionally, our findings that BMP-6 activates intracellular signalling pathways in human B cells might be of potential pathophysiological significance in lymphoma and inflammation.
T7852 6493-6586 Sentence denotes High BMP-6 mRNA expression in DLBCL has been shown to correlate to unfavourable outcome [12].
T7853 6587-6783 Sentence denotes In this respect, it is of interest that targeted expression of Id1 to B-lymphocytes resulted in aberrant B cell development, massive apoptosis, and subsequent development of B cell lymphomas [35].
T7854 6784-6957 Sentence denotes Moreover, BMP-6 has been suggested to play a role in rheumatoid arthritis (RA) [43,44] and elevated levels of Id1 and Id3 have been found in the synovia of RA-patients [45].
T7855 6958-7118 Sentence denotes Altogether, these results point to an important role for Id proteins in the regulation of normal B cell homeostasis and in diseases, where B cells are involved.
T7856 7119-7272 Sentence denotes It will therefore be important to further elucidate the role of Id-1 in human B cells by selective over expression or inhibition of Id-1 gene expression.
T7857 7273-7513 Sentence denotes Given the role of BMP-6 in mature human B cells demonstrated here, identification of BMP-6 producing cells in vivo with possibility of interaction with naïve and memory B cells might contribute to the understanding of mature B cell biology.
T7858 7514-7602 Sentence denotes High BMP-6 mRNA expression in DLBCL has been detected by gene expression profiling [12].
T7859 7603-7707 Sentence denotes Furthermore, production of BMP-6 transcripts in normal activated B cells was detected in the same study.
T7860 7708-7815 Sentence denotes Of note, an autocrine BMP-6 loop has been reported by others in chondrocytes and in the ovarium [46,19,18].
T7861 7816-7909 Sentence denotes Therefore, we wanted to explore the possibility for an autocrine BMP-6 loop in human B cells.
T7862 7910-8134 Sentence denotes We analysed the expression BMP-6 mRNA in peripheral blood B cells by real-time PCR, and report here the upregulation of endogenous BMP-6 transcripts after stimulation with FCS, human AB-serum and, most importantly, anti-IgM.
T7863 8135-8357 Sentence denotes However, our attempts to study BMP-6 protein levels were unsuccessful due to problems with unspecific binding of the anti-BMP-6 antibodies tested, and lack of specific staining in control cells known to express BMP-6 mRNA.
T7864 8358-8416 Sentence denotes In contrast, the recombinant protein was readily detected.
T7865 8417-8527 Sentence denotes In that respect, few investigators have detected BMP-6 protein in humans, especially in non-pathogenic tissue.
T7866 8528-8737 Sentence denotes The possibility of BMP-6 production in human B-cells is in line with a recent work that reported the production of BMP-6 in mouse B cells, infiltrating the bone marrow of mice with inflammatory arthritis [43].
T7867 8738-8825 Sentence denotes In this study, a role for BMPs in the inflammatoric process of arthritis was suggested.
T7868 8826-8928 Sentence denotes The upregulation of the BMP-6-transcripts after IgM-crosslinking is of pathophysiologic interest [12].
T7869 8929-9108 Sentence denotes A loss of TGF-β-responsiveness has been suggested to be a critical contribution to malignant transformation [47,48] and similar oncogenic mechanisms have been postulated for BMPs.
T7870 9109-9265 Sentence denotes Lines of evidence suggest [49] that at early stages of carcinogenesis, BMP-6 is not a tumour promoter, but suppresses benign and malignant tumour outgrowth.
T7871 9266-9489 Sentence denotes These findings are in good agreement with previous findings for other TGF-β family members, including TGF-β1 and BMP-4 [50], indicating that cellular context of the BMP target cell might define the various observed effects.
T7872 9490-9790 Sentence denotes In contrast to the upregulation of BMP-6 transcript in B cells, we were not able to detect BMP-6 transcripts in human peripheral blood CD4+ or CD8+ T cells (resting or stimulated with anti-CD3 and anti-CD28; data not shown), consistent with the findings in T cell lines [20] and T cells in mice [43].
T7873 9791-9941 Sentence denotes Other potential BMP-6 sources for mature B cells in vivo might be other cells of the immune system or tissue with contact to the hematopoietic system.
T7874 9942-10038 Sentence denotes One well recognized source for BMP-6 production is the human bone and bone marrow stroma [51,8].
T7875 10039-10218 Sentence denotes Furthermore, it is noteworthy that human umbilical vein endothelial cells (HUVEC) highly express BMP-6 mRNA [52], and vascular endothelium has been reported to produce BMP-6 [53].
T7876 10219-10303 Sentence denotes These studies might imply a role for BMP-6 in transendothelial migration of B cells.
T7877 10304-10393 Sentence denotes BMP-6 mRNA has been demonstrated in murine macrophage cell lines, but not in humans [54].
T7878 10394-10552 Sentence denotes In accordance with these findings, other human cell lines of neutrophil and monocytic origin have been described to be negative for the BMP-6 transcript [20].
T7879 10553-10648 Sentence denotes To our knowledge, there is currently no report about BMP-6 production of human dendritic cells.
T94 0-10 Sentence denotes Discussion
T95 11-254 Sentence denotes Recent studies have demonstrated an important role for BMP superfamily members in hematopoietic stem cells, early thymocytes [6,7] and B-cell malignancies [8,11,12], but a role for BMPs in normal human B cells has previously not been reported.
T96 255-368 Sentence denotes The present study demonstrated a significant antiproliferative effect of BMP-6 in peripheral blood CD19+ B cells.
T97 369-483 Sentence denotes Additionally, BMP-6 induced cell death in CD27+ memory B cells as well as in a Burkitt lymphoma cell line (Ramos).
T98 484-569 Sentence denotes Importantly, BMP-6 induced a rapid and marked increase in Smad-1/5/8 phosphorylation.
T99 570-702 Sentence denotes Furthermore, the BMP-6 induced Smad phosphorylation was followed by a selective upregulation of Id1 mRNA and subsequent Id1 protein.
T100 703-839 Sentence denotes In the present study, the demonstrated antiproliferative effect of BMP-6 in anti-IgM treated B cells was significant and dose-dependent.
T101 840-966 Sentence denotes Importantly, the anti-proliferative effect of BMP-6 could be completely neutralized by the use of a natural inhibitor, Noggin.
T102 967-1059 Sentence denotes This is in line with others, showing that Noggin can function as a BMP-6 antagonist [21,22].
T103 1060-1215 Sentence denotes In addition, the combination of soluble BMP-RIB-Fc and BMP-RII-Fc fusion proteins also neutralized the anti-proliferative effect of BMP-6 in human B cells.
T104 1216-1322 Sentence denotes Interestingly, as for other TGF family members, bifunctional effects have also been demonstrated for BMPs.
T105 1323-1576 Sentence denotes Whereas several of the BMPs have been shown to promote proliferation in various cell types including condrocytes [23], liver [24] and granulosa cells [25], antiproliferative effects and induction of apoptosis has been reported for B and T lineage cells.
T106 1577-1729 Sentence denotes Similar effects as demonstrated for BMP-6 on human B cells in the present study, were demonstrated for BMP-2, 4, 6 and -7 in human myeloma cells [9-11].
T107 1730-1847 Sentence denotes Other members of the BMP-family have also been reported to induce apoptosis, including in mouse B lineage cells [26].
T108 1848-1905 Sentence denotes Additionally, BMP-4 inhibits thymocyte proliferation [6].
T109 1906-2042 Sentence denotes Taken together, these data suggest that the role of BMPs in the regulation of proliferation and apoptosis is highly cell type dependent.
T110 2043-2167 Sentence denotes To examine how BMP-6 exerts its functional effects in B cells, we analysed BMP receptor expression by western blot analysis.
T111 2168-2377 Sentence denotes Human peripheral B cells were found to express the BMP type I receptors Act-RIA and BMP-RIB, and the type II-receptors BMP-RII and Act-RIIb, which signal after binding of several BMPs, including BMP-6 [16,13].
T112 2378-2466 Sentence denotes To further explore BMP-6 induced signalling, activation of several pathways is possible.
T113 2467-2544 Sentence denotes The major signalling pathway known to date, is activation of R-Smads [13,27].
T114 2545-2675 Sentence denotes In that respect, BMPs have been shown to exert antiproliferative effects in B lineage cells via phosphorylation of R-Smad [11,28].
T115 2676-2761 Sentence denotes Furthermore, BMP-2 has been shown to induce activation of STAT3 in myeloma cells [9].
T116 2762-2832 Sentence denotes However, phosphorylation of R-Smad was not investigated in that study.
T117 2833-2897 Sentence denotes BMP-2 has also been shown to induce phosphorylation of p38 [29].
T118 2898-3095 Sentence denotes Thus, phosphorylation of p38, STAT3 and Smad1/5/8 represent important BMP-signalling pathways that mediated the effects of BMPs and even cross-talk between these pathways has been reported [29,30].
T119 3096-3241 Sentence denotes In the present study, we were not able to detect BMP-6-induced changes in the phosphorylation status of STAT3 or p38 in human peripheral B cells.
T120 3242-3312 Sentence denotes Instead, a rapid and marked phosphorylation of Smad1/5/8 was revealed.
T121 3313-3445 Sentence denotes In a parallel study, we have found that other BMPs also induced phosphorylation of Smad1/5/8 in peripheral B cells (data not shown).
T122 3446-3612 Sentence denotes We are currently pursuing microarray studies to identify the signalling pathways and target genes that are differently regulated by the various BMPs in human B cells.
T123 3613-3830 Sentence denotes Upregulation of Id1 via Smad1/5/8 phosphorylation is a known mechanism for BMP-6 signalling in other cell systems [31,32] and regulation of Id-proteins is thought to be an important mechanism for Smad-signalling [17].
T124 3831-4006 Sentence denotes In the present study, real-time RT-PCR experiments revealed a specific four-fold upregulation for Id1 in BMP-6-treated B cells, while the amount of Id2–Id4 remained unchanged.
T125 4007-4164 Sentence denotes In agreement with this, western blot analysis demonstrated an upregulation of Id1 protein, while the amount of Id2 and Id3 protein levels remained unchanged.
T126 4165-4367 Sentence denotes Previously, Id1 has been considered not to be expressed in later developmental stages than pro-B cells [33,34], and its constitutive expression has been reported to impair mouse B cell development [35].
T127 4368-4513 Sentence denotes Therefore, our demonstration of the time-dependent upregulation of Id1 mRNA and protein in mature normal human B cells is of particular interest.
T128 4514-4672 Sentence denotes In that respect, it is noteworthy that TGF-β signalling in early and mature B cells induces both Id2 and Id3 expression [36,37], but not Id1 (data not shown).
T129 4673-4781 Sentence denotes Interestingly, these results show that various members of the TGF-β family regulate Id proteins differently.
T130 4782-4871 Sentence denotes Id2 and Id3 are considered to be the Id proteins mainly expressed in mature B cells [38].
T131 4872-4988 Sentence denotes The present study also found Id2 and Id3 protein in B cells to be more highly expressed than Id1 in resting B cells.
T132 4989-5080 Sentence denotes However, BMP-6 did not induce significant changes in the protein expression of Id2 and Id3.
T133 5081-5191 Sentence denotes It is believed that Id proteins block differentiation and promote proliferation in various cell types [39,33].
T134 5192-5342 Sentence denotes Id proteins act as dominant-negative inhibitors of E-proteins and Pax5 function by forming dimers with these proteins, making them unable to bind DNA.
T135 5343-5475 Sentence denotes It has been proposed that the balance among E-proteins, Pax5 and Id proteins might have an important role in activated B cells [38].
T136 5476-5641 Sentence denotes In that respect, E-proteins have been implicated in both the promotion and inhibition of cell survival and growth at different points in lymphocyte development [40].
T137 5642-5911 Sentence denotes The antiproliferative and death inducing effect of BMP-6 in B cells with concomitant upregulation of Id1 protein is therefore in line with the view that Id proteins are required for the induction of growth arrest and apoptosis in B-lymphocyte progenitors by TGF-β [40].
T138 5912-6048 Sentence denotes Furthermore, Id proteins are known as important parts of signalling pathways involved in development, cell cycle and tumorigenesis [32].
T139 6049-6309 Sentence denotes It is well established that various members of the Id family are overexpressed in a range of human tumours and generally, Id1 appears to be the family member most widely overexpressed in a variety of human malignancies [41], including multiple myeloma [42,32].
T140 6310-6492 Sentence denotes Additionally, our findings that BMP-6 activates intracellular signalling pathways in human B cells might be of potential pathophysiological significance in lymphoma and inflammation.
T141 6493-6586 Sentence denotes High BMP-6 mRNA expression in DLBCL has been shown to correlate to unfavourable outcome [12].
T142 6587-6783 Sentence denotes In this respect, it is of interest that targeted expression of Id1 to B-lymphocytes resulted in aberrant B cell development, massive apoptosis, and subsequent development of B cell lymphomas [35].
T143 6784-6957 Sentence denotes Moreover, BMP-6 has been suggested to play a role in rheumatoid arthritis (RA) [43,44] and elevated levels of Id1 and Id3 have been found in the synovia of RA-patients [45].
T144 6958-7118 Sentence denotes Altogether, these results point to an important role for Id proteins in the regulation of normal B cell homeostasis and in diseases, where B cells are involved.
T145 7119-7272 Sentence denotes It will therefore be important to further elucidate the role of Id-1 in human B cells by selective over expression or inhibition of Id-1 gene expression.
T146 7273-7513 Sentence denotes Given the role of BMP-6 in mature human B cells demonstrated here, identification of BMP-6 producing cells in vivo with possibility of interaction with naïve and memory B cells might contribute to the understanding of mature B cell biology.
T147 7514-7602 Sentence denotes High BMP-6 mRNA expression in DLBCL has been detected by gene expression profiling [12].
T148 7603-7707 Sentence denotes Furthermore, production of BMP-6 transcripts in normal activated B cells was detected in the same study.
T149 7708-7815 Sentence denotes Of note, an autocrine BMP-6 loop has been reported by others in chondrocytes and in the ovarium [46,19,18].
T150 7816-7909 Sentence denotes Therefore, we wanted to explore the possibility for an autocrine BMP-6 loop in human B cells.
T151 7910-8134 Sentence denotes We analysed the expression BMP-6 mRNA in peripheral blood B cells by real-time PCR, and report here the upregulation of endogenous BMP-6 transcripts after stimulation with FCS, human AB-serum and, most importantly, anti-IgM.
T152 8135-8357 Sentence denotes However, our attempts to study BMP-6 protein levels were unsuccessful due to problems with unspecific binding of the anti-BMP-6 antibodies tested, and lack of specific staining in control cells known to express BMP-6 mRNA.
T153 8358-8416 Sentence denotes In contrast, the recombinant protein was readily detected.
T154 8417-8527 Sentence denotes In that respect, few investigators have detected BMP-6 protein in humans, especially in non-pathogenic tissue.
T155 8528-8737 Sentence denotes The possibility of BMP-6 production in human B-cells is in line with a recent work that reported the production of BMP-6 in mouse B cells, infiltrating the bone marrow of mice with inflammatory arthritis [43].
T156 8738-8825 Sentence denotes In this study, a role for BMPs in the inflammatoric process of arthritis was suggested.
T157 8826-8928 Sentence denotes The upregulation of the BMP-6-transcripts after IgM-crosslinking is of pathophysiologic interest [12].
T158 8929-9108 Sentence denotes A loss of TGF-β-responsiveness has been suggested to be a critical contribution to malignant transformation [47,48] and similar oncogenic mechanisms have been postulated for BMPs.
T159 9109-9265 Sentence denotes Lines of evidence suggest [49] that at early stages of carcinogenesis, BMP-6 is not a tumour promoter, but suppresses benign and malignant tumour outgrowth.
T160 9266-9489 Sentence denotes These findings are in good agreement with previous findings for other TGF-β family members, including TGF-β1 and BMP-4 [50], indicating that cellular context of the BMP target cell might define the various observed effects.
T161 9490-9790 Sentence denotes In contrast to the upregulation of BMP-6 transcript in B cells, we were not able to detect BMP-6 transcripts in human peripheral blood CD4+ or CD8+ T cells (resting or stimulated with anti-CD3 and anti-CD28; data not shown), consistent with the findings in T cell lines [20] and T cells in mice [43].
T162 9791-9941 Sentence denotes Other potential BMP-6 sources for mature B cells in vivo might be other cells of the immune system or tissue with contact to the hematopoietic system.
T163 9942-10038 Sentence denotes One well recognized source for BMP-6 production is the human bone and bone marrow stroma [51,8].
T164 10039-10218 Sentence denotes Furthermore, it is noteworthy that human umbilical vein endothelial cells (HUVEC) highly express BMP-6 mRNA [52], and vascular endothelium has been reported to produce BMP-6 [53].
T165 10219-10303 Sentence denotes These studies might imply a role for BMP-6 in transendothelial migration of B cells.
T166 10304-10393 Sentence denotes BMP-6 mRNA has been demonstrated in murine macrophage cell lines, but not in humans [54].
T167 10394-10552 Sentence denotes In accordance with these findings, other human cell lines of neutrophil and monocytic origin have been described to be negative for the BMP-6 transcript [20].
T168 10553-10648 Sentence denotes To our knowledge, there is currently no report about BMP-6 production of human dendritic cells.

ICD10

Id Subject Object Predicate Lexical cue
T12302 6284-6300 http://purl.bioontology.org/ontology/ICD10/C90.0 denotes multiple myeloma
T12303 6837-6857 http://purl.bioontology.org/ontology/ICD10/M06.9 denotes rheumatoid arthritis
T12304 6848-6857 http://purl.bioontology.org/ontology/ICD10/M13.9 denotes arthritis
T12305 8722-8731 http://purl.bioontology.org/ontology/ICD10/M13.9 denotes arthritis
T12306 8801-8810 http://purl.bioontology.org/ontology/ICD10/M13.9 denotes arthritis

events-check-again

Id Subject Object Predicate Lexical cue Negation Speculation
T12962 328-333 Protein denotes BMP-6
T12963 354-358 Protein denotes CD19
T12964 383-388 Protein denotes BMP-6
T12965 411-415 Protein denotes CD27
T12966 497-502 Protein denotes BMP-6
T12967 503-510 Positive_regulation denotes induced
T12968 503-510 Positive_regulation denotes induced
T12969 503-510 Positive_regulation denotes induced
T12970 530-538 Positive_regulation denotes increase
T12971 530-538 Positive_regulation denotes increase
T12972 530-538 Positive_regulation denotes increase
T12973 542-548 Protein denotes Smad-1
T12974 549-550 Protein denotes 5
T12975 551-552 Protein denotes 8
T12976 553-568 Phosphorylation denotes phosphorylation
T12977 553-568 Phosphorylation denotes phosphorylation
T12978 553-568 Phosphorylation denotes phosphorylation
T12979 587-592 Protein denotes BMP-6
T12980 593-600 Positive_regulation denotes induced
T12981 601-605 Protein denotes Smad
T12982 606-621 Phosphorylation denotes phosphorylation
T12983 626-634 Positive_regulation denotes followed
T12984 626-634 Positive_regulation denotes followed
T12985 650-662 Positive_regulation denotes upregulation
T12986 650-662 Positive_regulation denotes upregulation
T12987 666-669 Protein denotes Id1
T12988 690-693 Protein denotes Id1
T12989 770-775 Protein denotes BMP-6
T12990 886-891 Protein denotes BMP-6
T12991 959-965 Protein denotes Noggin
T12992 1009-1015 Protein denotes Noggin
T12993 1034-1039 Protein denotes BMP-6
T12994 1040-1050 Negative_regulation denotes antagonist
T12995 1100-1107 Protein denotes BMP-RIB
T12996 1115-1122 Protein denotes BMP-RII
T12997 1192-1197 Protein denotes BMP-6
T12998 1613-1618 Protein denotes BMP-6
T12999 1680-1685 Protein denotes BMP-2
T13000 1687-1688 Protein denotes 4
T13001 1690-1691 Protein denotes 6
T13002 1696-1698 Protein denotes -7
T13003 1862-1867 Protein denotes BMP-4
T13004 2058-2063 Protein denotes BMP-6
T13005 2207-2214 Gene_expression denotes express
T13006 2207-2214 Gene_expression denotes express
T13007 2207-2214 Gene_expression denotes express
T13008 2207-2214 Gene_expression denotes express
T13009 2240-2247 Protein denotes Act-RIA
T13010 2252-2259 Protein denotes BMP-RIB
T13011 2287-2294 Protein denotes BMP-RII
T13012 2299-2307 Protein denotes Act-RIIb
T13013 2328-2335 Binding denotes binding
T13014 2328-2335 Binding denotes binding
T13015 2328-2335 Binding denotes binding
T13016 2328-2335 Binding denotes binding
T13017 2363-2368 Protein denotes BMP-6
T13018 2397-2402 Protein denotes BMP-6
T13019 2689-2694 Protein denotes BMP-2
T13020 2713-2719 Positive_regulation denotes induce
T13021 2720-2730 Positive_regulation denotes activation
T13022 2734-2739 Protein denotes STAT3
T13023 2833-2838 Protein denotes BMP-2
T13024 2904-2919 Phosphorylation denotes phosphorylation
T13025 2904-2919 Phosphorylation denotes phosphorylation
T13026 2904-2919 Phosphorylation denotes phosphorylation
T13027 2904-2919 Phosphorylation denotes phosphorylation
T13028 2928-2933 Protein denotes STAT3
T13029 2938-2943 Protein denotes Smad1
T13030 2944-2945 Protein denotes 5
T13031 2946-2947 Protein denotes 8
T13032 3145-3150 Protein denotes BMP-6
T13033 3151-3158 Positive_regulation denotes induced true
T13034 3159-3166 Regulation denotes changes
T13035 3174-3189 Phosphorylation denotes phosphorylation
T13036 3200-3205 Protein denotes STAT3
T13037 3270-3285 Phosphorylation denotes phosphorylation
T13038 3270-3285 Phosphorylation denotes phosphorylation
T13039 3270-3285 Phosphorylation denotes phosphorylation
T13040 3289-3294 Protein denotes Smad1
T13041 3295-3296 Protein denotes 5
T13042 3297-3298 Protein denotes 8
T13043 3369-3376 Positive_regulation denotes induced
T13044 3369-3376 Positive_regulation denotes induced
T13045 3369-3376 Positive_regulation denotes induced
T13046 3377-3392 Phosphorylation denotes phosphorylation
T13047 3377-3392 Phosphorylation denotes phosphorylation
T13048 3377-3392 Phosphorylation denotes phosphorylation
T13049 3396-3401 Protein denotes Smad1
T13050 3402-3403 Protein denotes 5
T13051 3404-3405 Protein denotes 8
T13052 3613-3625 Positive_regulation denotes Upregulation
T13053 3613-3625 Positive_regulation denotes Upregulation
T13054 3613-3625 Positive_regulation denotes Upregulation
T13055 3629-3632 Protein denotes Id1
T13056 3637-3642 Protein denotes Smad1
T13057 3643-3644 Protein denotes 5
T13058 3645-3646 Protein denotes 8
T13059 3647-3662 Phosphorylation denotes phosphorylation
T13060 3647-3662 Phosphorylation denotes phosphorylation
T13061 3647-3662 Phosphorylation denotes phosphorylation
T13062 3674-3683 Regulation denotes mechanism
T13063 3674-3683 Regulation denotes mechanism
T13064 3674-3683 Regulation denotes mechanism
T13065 3688-3693 Protein denotes BMP-6
T13066 3912-3924 Positive_regulation denotes upregulation
T13067 3929-3932 Protein denotes Id1
T13068 3936-3941 Protein denotes BMP-6
T13069 3969-3975 Gene_expression denotes amount
T13070 3969-3975 Gene_expression denotes amount
T13071 3979-3982 Protein denotes Id2
T13072 3983-3986 Protein denotes Id4
T13073 3987-4005 Positive_regulation denotes remained unchanged true
T13074 3987-4005 Positive_regulation denotes remained unchanged true
T13075 4069-4081 Positive_regulation denotes upregulation
T13076 4085-4088 Protein denotes Id1
T13077 4108-4114 Gene_expression denotes amount
T13078 4108-4114 Gene_expression denotes amount
T13079 4118-4121 Protein denotes Id2
T13080 4126-4129 Protein denotes Id3
T13081 4145-4163 Positive_regulation denotes remained unchanged true
T13082 4145-4163 Positive_regulation denotes remained unchanged true
T13083 4177-4180 Protein denotes Id1
T13084 4211-4220 Gene_expression denotes expressed true true
T13085 4298-4308 Gene_expression denotes expression
T13086 4419-4431 Positive_regulation denotes upregulation
T13087 4435-4438 Protein denotes Id1
T13088 4553-4558 Protein denotes TGF-β
T13089 4598-4605 Positive_regulation denotes induces
T13090 4598-4605 Positive_regulation denotes induces true
T13091 4598-4605 Positive_regulation denotes induces
T13092 4611-4614 Protein denotes Id2
T13093 4619-4622 Protein denotes Id3
T13094 4623-4633 Gene_expression denotes expression
T13095 4623-4633 Gene_expression denotes expression
T13096 4651-4654 Protein denotes Id1
T13097 4735-4740 Protein denotes TGF-β
T13098 4782-4785 Protein denotes Id2
T13099 4790-4793 Protein denotes Id3
T13100 4838-4847 Gene_expression denotes expressed true
T13101 4838-4847 Gene_expression denotes expressed true
T13102 4901-4904 Protein denotes Id2
T13103 4909-4912 Protein denotes Id3
T13104 4950-4959 Gene_expression denotes expressed
T13105 4950-4959 Gene_expression denotes expressed
T13106 4950-4959 Gene_expression denotes expressed
T13107 4965-4968 Protein denotes Id1
T13108 4998-5003 Protein denotes BMP-6
T13109 5012-5018 Positive_regulation denotes induce true
T13110 5012-5018 Positive_regulation denotes induce true
T13111 5031-5038 Regulation denotes changes
T13112 5031-5038 Regulation denotes changes
T13113 5054-5064 Gene_expression denotes expression
T13114 5054-5064 Gene_expression denotes expression
T13115 5068-5071 Protein denotes Id2
T13116 5076-5079 Protein denotes Id3
T13117 5229-5239 Negative_regulation denotes inhibitors
T13118 5258-5262 Protein denotes Pax5
T13119 5275-5289 Binding denotes forming dimers
T13120 5311-5317 Positive_regulation denotes making
T13121 5333-5337 Binding denotes bind true
T13122 5399-5403 Protein denotes Pax5
T13123 5693-5698 Protein denotes BMP-6
T13124 5727-5739 Positive_regulation denotes upregulation
T13125 5743-5746 Protein denotes Id1
T13126 5900-5905 Protein denotes TGF-β
T13127 6171-6174 Protein denotes Id1
T13128 6219-6232 Positive_regulation denotes overexpressed true
T13129 6342-6347 Protein denotes BMP-6
T13130 6493-6497 Positive_regulation denotes High
T13131 6498-6503 Protein denotes BMP-6
T13132 6504-6519 Transcription denotes mRNA expression
T13133 6636-6646 Gene_expression denotes expression
T13134 6650-6653 Protein denotes Id1
T13135 6794-6799 Protein denotes BMP-6
T13136 6875-6883 Positive_regulation denotes elevated
T13137 6875-6883 Positive_regulation denotes elevated
T13138 6884-6890 Gene_expression denotes levels
T13139 6884-6890 Gene_expression denotes levels
T13140 6894-6897 Protein denotes Id1
T13141 6902-6905 Protein denotes Id3
T13142 7183-7187 Protein denotes Id-1
T13143 7218-7222 Positive_regulation denotes over
T13144 7223-7233 Gene_expression denotes expression
T13145 7237-7247 Negative_regulation denotes inhibition
T13146 7251-7255 Protein denotes Id-1
T13147 7261-7271 Gene_expression denotes expression
T13148 7291-7296 Protein denotes BMP-6
T13149 7358-7363 Protein denotes BMP-6
T13150 7364-7373 Gene_expression denotes producing
T13151 7514-7518 Positive_regulation denotes High
T13152 7519-7524 Protein denotes BMP-6
T13153 7525-7540 Transcription denotes mRNA expression
T13154 7616-7626 Transcription denotes production
T13155 7630-7635 Protein denotes BMP-6
T13156 7720-7729 Regulation denotes autocrine
T13157 7730-7735 Protein denotes BMP-6
T13158 7871-7880 Regulation denotes autocrine true
T13159 7881-7886 Protein denotes BMP-6
T13160 7926-7936 Transcription denotes expression true
T13161 7937-7942 Protein denotes BMP-6
T13162 8014-8026 Positive_regulation denotes upregulation
T13163 8041-8046 Protein denotes BMP-6
T13164 8166-8171 Protein denotes BMP-6
T13165 8338-8345 Transcription denotes express
T13166 8346-8351 Protein denotes BMP-6
T13167 8457-8465 Gene_expression denotes detected true
T13168 8466-8471 Protein denotes BMP-6
T13169 8547-8552 Protein denotes BMP-6
T13170 8553-8563 Gene_expression denotes production true
T13171 8629-8639 Gene_expression denotes production
T13172 8643-8648 Protein denotes BMP-6
T13173 8830-8842 Positive_regulation denotes upregulation
T13174 8850-8855 Protein denotes BMP-6
T13175 8939-8944 Protein denotes TGF-β
T13176 9180-9185 Protein denotes BMP-6
T13177 9336-9341 Protein denotes TGF-β
T13178 9368-9374 Protein denotes TGF-β1
T13179 9379-9384 Protein denotes BMP-4
T13180 9509-9521 Positive_regulation denotes upregulation
T13181 9525-9530 Protein denotes BMP-6
T13182 9574-9580 Transcription denotes detect true
T13183 9581-9586 Protein denotes BMP-6
T13184 9625-9628 Protein denotes CD4
T13185 9633-9636 Protein denotes CD8
T13186 9679-9682 Protein denotes CD3
T13187 9692-9696 Protein denotes CD28
T13188 9807-9812 Protein denotes BMP-6
T13189 9973-9978 Protein denotes BMP-6
T13190 9979-9989 Gene_expression denotes production
T13191 10121-10127 Positive_regulation denotes highly
T13192 10128-10135 Transcription denotes express
T13193 10136-10141 Protein denotes BMP-6
T13194 10199-10206 Gene_expression denotes produce
T13195 10207-10212 Protein denotes BMP-6
T13196 10256-10261 Protein denotes BMP-6
T13197 10304-10309 Protein denotes BMP-6
T13198 10324-10336 Transcription denotes demonstrated true
T13199 10513-10521 Transcription denotes negative true
T13200 10530-10535 Protein denotes BMP-6
T13201 10606-10611 Protein denotes BMP-6
T13202 10612-10622 Gene_expression denotes production true true
R10251 T13029 T13025 themeOf Smad1,phosphorylation
R10252 T13030 T13024 themeOf 5,phosphorylation
R10253 T13031 T13027 themeOf 8,phosphorylation
R10254 T13032 T13033 causeOf BMP-6,induced
R10255 T13092 T13095 themeOf Id2,expression
R10333 T13140 T13138 themeOf Id1,levels
R10334 T13141 T13139 themeOf Id3,levels
R10335 T13144 T13143 themeOf expression,over
R10336 T13146 T13144 themeOf Id-1,expression
R10337 T13146 T13147 themeOf Id-1,expression
R10338 T13147 T13145 themeOf expression,inhibition
R10339 T13149 T13150 themeOf BMP-6,producing
R10341 T13152 T13153 themeOf BMP-6,mRNA expression
R10344 T13153 T13151 themeOf mRNA expression,High
R10345 T13155 T13154 themeOf BMP-6,production
R10346 T13157 T13156 themeOf BMP-6,autocrine
R10351 T13157 T13156 causeOf BMP-6,autocrine
R10188 T12966 T12968 causeOf BMP-6,induced
R10189 T12966 T12967 causeOf BMP-6,induced
R10190 T12966 T12969 causeOf BMP-6,induced
R10192 T12970 T12969 themeOf increase,induced
R10193 T12971 T12967 themeOf increase,induced
R10195 T12972 T12968 themeOf increase,induced
R10196 T12973 T12976 themeOf Smad-1,phosphorylation
R10197 T12974 T12978 themeOf 5,phosphorylation
R10198 T12975 T12977 themeOf 8,phosphorylation
R10199 T12976 T12972 themeOf phosphorylation,increase
R10201 T12977 T12970 themeOf phosphorylation,increase
R10202 T12978 T12971 themeOf phosphorylation,increase
R10203 T12979 T12980 causeOf BMP-6,induced
R10204 T13060 T13053 causeOf phosphorylation,Upregulation
R10205 T12981 T12982 themeOf Smad,phosphorylation
R10206 T12982 T12980 themeOf phosphorylation,induced
R10207 T12982 T12983 causeOf phosphorylation,followed
R10208 T12982 T12984 causeOf phosphorylation,followed
R10209 T12985 T12983 themeOf upregulation,followed
R10210 T12986 T12984 themeOf upregulation,followed
R10211 T12987 T12985 themeOf Id1,upregulation
R10212 T13061 T13054 causeOf phosphorylation,Upregulation
R10213 T12988 T12986 themeOf Id1,upregulation
R10214 T13065 T13062 causeOf BMP-6,mechanism
R10215 T12992 T12994 causeOf Noggin,antagonist
R10216 T12993 T12994 themeOf BMP-6,antagonist
R10217 T13065 T13063 causeOf BMP-6,mechanism
R10218 T13065 T13064 causeOf BMP-6,mechanism
R10219 T13067 T13066 themeOf Id1,upregulation
R10220 T13068 T13066 causeOf BMP-6,upregulation
R10221 T13068 T13073 causeOf BMP-6,remained unchanged
R10222 T13068 T13074 causeOf BMP-6,remained unchanged
R10223 T13069 T13074 themeOf amount,remained unchanged
R10224 T13009 T13007 themeOf Act-RIA,express
R10225 T13009 T13016 themeOf Act-RIA,binding
R10226 T13070 T13073 themeOf amount,remained unchanged
R10227 T13010 T13005 themeOf BMP-RIB,express
R10228 T13071 T13070 themeOf Id2,amount
R10229 T13072 T13069 themeOf Id4,amount
R10230 T13010 T13014 themeOf BMP-RIB,binding
R10231 T13076 T13075 themeOf Id1,upregulation
R10232 T13011 T13006 themeOf BMP-RII,express
R10233 T13011 T13015 themeOf BMP-RII,binding
R10234 T13012 T13008 themeOf Act-RIIb,express
R10235 T13012 T13013 themeOf Act-RIIb,binding
R10236 T13077 T13082 themeOf amount,remained unchanged
R10237 T13017 T13016 themeOf BMP-6,binding
R10238 T13017 T13014 themeOf BMP-6,binding
R10239 T13017 T13015 themeOf BMP-6,binding
R10240 T13017 T13013 themeOf BMP-6,binding
R10241 T13019 T13020 causeOf BMP-2,induce
R10242 T13078 T13081 themeOf amount,remained unchanged
R10243 T13021 T13020 themeOf activation,induce
R10244 T13022 T13021 themeOf STAT3,activation
R10245 T13079 T13078 themeOf Id2,amount
R10246 T13080 T13077 themeOf Id3,amount
R10247 T13083 T13084 themeOf Id1,expressed
R10248 T13028 T13026 themeOf STAT3,phosphorylation
R10249 T13083 T13085 themeOf Id1,expression
R10250 T13087 T13086 themeOf Id1,upregulation
R10256 T13034 T13033 themeOf changes,induced
R10257 T13035 T13034 themeOf phosphorylation,changes
R10258 T13036 T13035 themeOf STAT3,phosphorylation
R10259 T13093 T13094 themeOf Id3,expression
R10260 T13040 T13038 themeOf Smad1,phosphorylation
R10261 T13041 T13039 themeOf 5,phosphorylation
R10262 T13042 T13037 themeOf 8,phosphorylation
R10263 T13094 T13091 themeOf expression,induces
R10264 T13095 T13089 themeOf expression,induces
R10265 T13046 T13044 themeOf phosphorylation,induced
R10266 T13047 T13045 themeOf phosphorylation,induced
R10267 T13096 T13090 themeOf Id1,induces
R10268 T13048 T13043 themeOf phosphorylation,induced
R10269 T13049 T13046 themeOf Smad1,phosphorylation
R10270 T13050 T13047 themeOf 5,phosphorylation
R10271 T13098 T13101 themeOf Id2,expressed
R10272 T13051 T13048 themeOf 8,phosphorylation
R10273 T13052 T13063 themeOf Upregulation,mechanism
R10274 T13053 T13064 themeOf Upregulation,mechanism
R10275 T13099 T13100 themeOf Id3,expressed
R10276 T13054 T13062 themeOf Upregulation,mechanism
R10277 T13055 T13054 themeOf Id1,Upregulation
R10278 T13055 T13052 themeOf Id1,Upregulation
R10279 T13055 T13053 themeOf Id1,Upregulation
R10280 T13056 T13061 themeOf Smad1,phosphorylation
R10281 T13057 T13059 themeOf 5,phosphorylation
R10282 T13058 T13060 themeOf 8,phosphorylation
R10283 T13059 T13052 causeOf phosphorylation,Upregulation
R10284 T13102 T13106 themeOf Id2,expressed
R10285 T13103 T13104 themeOf Id3,expressed
R10286 T13107 T13105 themeOf Id1,expressed
R10287 T13159 T13158 themeOf BMP-6,autocrine
R10288 T13159 T13158 causeOf BMP-6,autocrine
R10289 T13161 T13160 themeOf BMP-6,expression
R10290 T13108 T13109 causeOf BMP-6,induce
R10291 T13163 T13162 themeOf BMP-6,upregulation
R10292 T13108 T13110 causeOf BMP-6,induce
R10293 T13111 T13109 themeOf changes,induce
R10294 T13166 T13165 themeOf BMP-6,express
R10295 T13168 T13167 themeOf BMP-6,detected
R10296 T13169 T13170 themeOf BMP-6,production
R10297 T13112 T13110 themeOf changes,induce
R10298 T13172 T13171 themeOf BMP-6,production
R10299 T13113 T13111 themeOf expression,changes
R10300 T13174 T13173 themeOf BMP-6,upregulation
R10301 T13114 T13112 themeOf expression,changes
R10302 T13115 T13113 themeOf Id2,expression
R10303 T13116 T13114 themeOf Id3,expression
R10304 T13181 T13180 themeOf BMP-6,upregulation
R10305 T13183 T13182 themeOf BMP-6,detect
R10306 T13118 T13117 themeOf Pax5,inhibitors
R10307 T13118 T13119 themeOf Pax5,forming dimers
R10308 T13118 T13121 themeOf Pax5,bind
R10309 T13189 T13190 themeOf BMP-6,production
R10310 T13119 T13117 causeOf forming dimers,inhibitors
R10311 T13192 T13191 themeOf express,highly
R10312 T13119 T13120 causeOf forming dimers,making
R10313 T13193 T13192 themeOf BMP-6,express
R10314 T13121 T13120 themeOf bind,making
R10315 T13195 T13194 themeOf BMP-6,produce
R10316 T13197 T13198 themeOf BMP-6,demonstrated
R10317 T13123 T13124 causeOf BMP-6,upregulation
R10318 T13200 T13199 themeOf BMP-6,negative
R10319 T13201 T13202 themeOf BMP-6,production
R10320 T13125 T13124 themeOf Id1,upregulation
R10321 T13127 T13128 themeOf Id1,overexpressed
R10322 T13131 T13132 themeOf BMP-6,mRNA expression
R10323 T13132 T13130 themeOf mRNA expression,High
R10324 T13134 T13133 themeOf Id1,expression
R10325 T13138 T13137 themeOf levels,elevated
R10328 T13139 T13136 themeOf levels,elevated

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T12307 66-89 Protein denotes BMP superfamily members
T12308 192-196 Protein denotes BMPs
T12309 354-359 Protein denotes CD19+
T12310 411-415 Protein denotes CD27
T12311 497-502 Protein denotes BMP-6
T12312 587-592 Protein denotes BMP-6
T12313 593-600 Positive_regulation denotes induced
T12314 601-605 Protein denotes Smad
T12315 606-621 Phosphorylation denotes phosphorylation
T12316 626-634 Positive_regulation denotes followed
T12317 650-662 Positive_regulation denotes upregulation
T12318 650-662 Positive_regulation denotes upregulation
T12319 666-674 Protein denotes Id1 mRNA
T12320 690-701 Protein denotes Id1 protein
T12321 770-775 Protein denotes BMP-6
T12322 779-787 Protein denotes anti-IgM
T12323 886-891 Protein denotes BMP-6
T12324 959-965 Protein denotes Noggin
T12325 1009-1015 Protein denotes Noggin
T12326 1100-1110 Protein denotes BMP-RIB-Fc
T12327 1115-1118 Protein denotes BMP
T12328 1119-1122 Protein denotes RII
T12329 1123-1125 Protein denotes Fc
T12330 1192-1197 Protein denotes BMP-6
T12331 1244-1262 Protein denotes TGF family members
T12332 1613-1618 Protein denotes BMP-6
T12333 1751-1761 Protein denotes BMP-family
T12334 1958-1962 Protein denotes BMPs
T12335 2118-2130 Protein denotes BMP receptor
T12336 2131-2141 Gene_expression denotes expression
T12337 2207-2214 Gene_expression denotes express
T12338 2207-2214 Gene_expression denotes express
T12339 2207-2214 Gene_expression denotes express
T12340 2207-2214 Gene_expression denotes express
T12341 2219-2239 Protein denotes BMP type I receptors
T12342 2269-2294 Protein denotes type II-receptors BMP-RII
T12343 2299-2302 Protein denotes Act
T12344 2303-2307 Protein denotes RIIb
T12345 2328-2335 Binding denotes binding
T12346 2328-2335 Binding denotes binding
T12347 2720-2730 Positive_regulation denotes activation
T12348 2734-2739 Protein denotes STAT3
T12349 2771-2786 Phosphorylation denotes phosphorylation
T12350 2771-2786 Phosphorylation denotes phosphorylation
T12351 2790-2791 Protein denotes R
T12352 2792-2796 Protein denotes Smad
T12353 2904-2919 Phosphorylation denotes phosphorylation
T12354 2904-2919 Phosphorylation denotes phosphorylation
T12355 2904-2919 Phosphorylation denotes phosphorylation
T12356 2923-2926 Protein denotes p38
T12357 2928-2933 Protein denotes STAT3
T12358 2938-2947 Protein denotes Smad1/5/8
T12359 3159-3166 Regulation denotes changes
T12360 3159-3166 Regulation denotes changes
T12361 3174-3189 Phosphorylation denotes phosphorylation
T12362 3174-3189 Phosphorylation denotes phosphorylation
T12363 3200-3205 Protein denotes STAT3
T12364 3209-3212 Protein denotes p38
T12365 3270-3285 Phosphorylation denotes phosphorylation
T12366 3289-3298 Protein denotes Smad1/5/8
T12367 3369-3376 Positive_regulation denotes induced
T12368 3377-3392 Phosphorylation denotes phosphorylation
T12369 3396-3405 Protein denotes Smad1/5/8
T12370 3590-3594 Protein denotes BMPs
T12371 3613-3625 Positive_regulation denotes Upregulation
T12372 3629-3632 Protein denotes Id1
T12373 3637-3642 Protein denotes Smad1
T12374 3647-3662 Phosphorylation denotes phosphorylation
T12375 3688-3693 Protein denotes BMP-6
T12376 3739-3749 Regulation denotes regulation
T12377 3753-3764 Protein denotes Id-proteins
T12378 3912-3924 Positive_regulation denotes upregulation
T12379 3929-3932 Protein denotes Id1
T12380 3979-3986 Protein denotes Id2–Id4
T12381 4069-4081 Positive_regulation denotes upregulation
T12382 4085-4096 Protein denotes Id1 protein
T12383 4108-4114 Gene_expression denotes amount
T12384 4108-4114 Gene_expression denotes amount
T12385 4118-4121 Protein denotes Id2
T12386 4126-4137 Protein denotes Id3 protein
T12387 4177-4180 Protein denotes Id1
T12388 4211-4220 Gene_expression denotes expressed
T12389 4298-4308 Gene_expression denotes expression
T12390 4419-4431 Positive_regulation denotes upregulation
T12391 4435-4443 Protein denotes Id1 mRNA
T12392 4553-4558 Protein denotes TGF-β
T12393 4598-4605 Positive_regulation denotes induces
T12394 4598-4605 Positive_regulation denotes induces
T12395 4598-4605 Positive_regulation denotes induces
T12396 4611-4614 Protein denotes Id2
T12397 4619-4622 Protein denotes Id3
T12398 4623-4633 Gene_expression denotes expression
T12399 4623-4633 Gene_expression denotes expression
T12400 4623-4633 Gene_expression denotes expression
T12401 4651-4654 Protein denotes Id1
T12402 4735-4740 Protein denotes TGF-β
T12403 4748-4756 Regulation denotes regulate
T12404 4757-4768 Protein denotes Id proteins
T12405 4782-4785 Protein denotes Id2
T12406 4790-4793 Protein denotes Id3
T12407 4819-4830 Protein denotes Id proteins
T12408 4838-4847 Gene_expression denotes expressed
T12409 4838-4847 Gene_expression denotes expressed
T12410 4838-4847 Gene_expression denotes expressed
T12411 4901-4904 Protein denotes Id2
T12412 4909-4920 Protein denotes Id3 protein
T12413 4950-4959 Gene_expression denotes expressed
T12414 4950-4959 Gene_expression denotes expressed
T12415 4950-4959 Gene_expression denotes expressed
T12416 4965-4968 Protein denotes Id1
T12417 5012-5018 Positive_regulation denotes induce
T12418 5012-5018 Positive_regulation denotes induce
T12419 5054-5064 Gene_expression denotes expression
T12420 5054-5064 Gene_expression denotes expression
T12421 5068-5071 Protein denotes Id2
T12422 5076-5079 Protein denotes Id3
T12423 5101-5112 Protein denotes Id proteins
T12424 5192-5203 Protein denotes Id proteins
T12425 5229-5239 Negative_regulation denotes inhibitors
T12426 5258-5262 Protein denotes Pax5
T12427 5399-5403 Protein denotes Pax5
T12428 5408-5419 Protein denotes Id proteins
T12429 5727-5739 Positive_regulation denotes upregulation
T12430 5743-5754 Protein denotes Id1 protein
T12431 5795-5806 Protein denotes Id proteins
T12432 5925-5936 Protein denotes Id proteins
T12433 6100-6109 Protein denotes Id family
T12434 6114-6127 Gene_expression denotes overexpressed
T12435 6114-6127 Positive_regulation denotes overexpressed
T12436 6171-6174 Protein denotes Id1
T12437 6219-6232 Positive_regulation denotes overexpressed
T12438 6493-6508 Protein denotes High BMP-6 mRNA
T12439 6509-6519 Gene_expression denotes expression
T12440 6636-6646 Gene_expression denotes expression
T12441 6650-6653 Protein denotes Id1
T12442 6794-6799 Protein denotes BMP-6
T12443 6875-6883 Positive_regulation denotes elevated
T12444 6875-6883 Positive_regulation denotes elevated
T12445 6884-6890 Gene_expression denotes levels
T12446 6884-6890 Gene_expression denotes levels
T12447 6894-6897 Protein denotes Id1
T12448 6902-6905 Protein denotes Id3
T12449 7015-7026 Protein denotes Id proteins
T12450 7183-7187 Protein denotes Id-1
T12451 7237-7247 Negative_regulation denotes inhibition
T12452 7251-7260 Protein denotes Id-1 gene
T12453 7261-7271 Gene_expression denotes expression
T12454 7291-7296 Protein denotes BMP-6
T12455 7514-7529 Protein denotes High BMP-6 mRNA
T12456 7530-7540 Gene_expression denotes expression
T12457 7616-7626 Gene_expression denotes production
T12458 7630-7647 Protein denotes BMP-6 transcripts
T12459 8125-8133 Protein denotes anti-IgM
T12460 8338-8345 Gene_expression denotes express
T12461 8346-8356 Protein denotes BMP-6 mRNA
T12462 8457-8465 Gene_expression denotes detected
T12463 8466-8479 Protein denotes BMP-6 protein
T12464 8629-8639 Gene_expression denotes production
T12465 8643-8648 Protein denotes BMP-6
T12466 8764-8768 Protein denotes BMPs
T12467 8830-8842 Positive_regulation denotes upregulation
T12468 8874-8877 Protein denotes IgM
T12469 9336-9356 Protein denotes TGF-β family members
T12470 9368-9374 Protein denotes TGF-β1
T12471 9574-9580 Transcription denotes detect
T12472 9581-9598 Protein denotes BMP-6 transcripts
T12473 9625-9629 Protein denotes CD4+
T12474 9633-9637 Protein denotes CD8+
T12475 9674-9682 Protein denotes anti-CD3
T12476 9687-9696 Protein denotes anti-CD28
T12477 10128-10135 Gene_expression denotes express
T12478 10136-10146 Protein denotes BMP-6 mRNA
T12479 10304-10314 Protein denotes BMP-6 mRNA
R9821 T12335 T12336 themeOf BMP receptor,expression
R9822 T12341 T12337 themeOf BMP type I receptors,express
R9823 T12342 T12338 themeOf type II-receptors BMP-RII,express
R9824 T12343 T12339 themeOf Act,express
R9825 T12343 T12345 themeOf Act,binding
R9826 T12344 T12340 themeOf RIIb,express
R9827 T12344 T12346 themeOf RIIb,binding
R9828 T12348 T12347 themeOf STAT3,activation
R9829 T12351 T12349 themeOf R,phosphorylation
R9830 T12352 T12350 themeOf Smad,phosphorylation
R9831 T12356 T12353 themeOf p38,phosphorylation
R9833 T12357 T12354 themeOf STAT3,phosphorylation
R9834 T12358 T12355 themeOf Smad1/5/8,phosphorylation
R9836 T12361 T12359 themeOf phosphorylation,changes
R9837 T12362 T12360 themeOf phosphorylation,changes
R9838 T12363 T12361 themeOf STAT3,phosphorylation
R9840 T12364 T12362 themeOf p38,phosphorylation
R9842 T12366 T12365 themeOf Smad1/5/8,phosphorylation
R9843 T12368 T12367 themeOf phosphorylation,induced
R9844 T12369 T12368 themeOf Smad1/5/8,phosphorylation
R9846 T12373 T12374 themeOf Smad1,phosphorylation
R9848 T12374 T12371 themeOf phosphorylation,Upregulation
R9849 T12377 T12376 themeOf Id-proteins,regulation
R9850 T12379 T12378 themeOf Id1,upregulation
R9851 T12382 T12381 themeOf Id1 protein,upregulation
R9852 T12385 T12383 themeOf Id2,amount
R9853 T12386 T12384 themeOf Id3 protein,amount
R9854 T12387 T12388 themeOf Id1,expressed
R9855 T12387 T12389 themeOf Id1,expression
R9881 T12445 T12443 themeOf levels,elevated
R9882 T12446 T12444 themeOf levels,elevated
R9883 T12447 T12445 themeOf Id1,levels
R9884 T12448 T12446 themeOf Id3,levels
R9885 T12452 T12453 themeOf Id-1 gene,expression
R9889 T12453 T12451 themeOf expression,inhibition
R9890 T12455 T12456 themeOf High BMP-6 mRNA,expression
R9891 T12458 T12457 themeOf BMP-6 transcripts,production
R9895 T12461 T12460 themeOf BMP-6 mRNA,express
R9900 T12463 T12462 themeOf BMP-6 protein,detected
R9904 T12465 T12464 themeOf BMP-6,production
R9909 T12468 T12467 themeOf IgM,upregulation
R9914 T12472 T12471 themeOf BMP-6 transcripts,detect
R9917 T12478 T12477 themeOf BMP-6 mRNA,express
R9785 T12312 T12313 causeOf BMP-6,induced
R9832 T12314 T12315 themeOf Smad,phosphorylation
R9835 T12315 T12316 themeOf phosphorylation,followed
R9839 T12315 T12313 themeOf phosphorylation,induced
R9841 T12319 T12317 themeOf Id1 mRNA,upregulation
R9845 T12320 T12318 themeOf Id1 protein,upregulation
R9847 T12419 T12417 themeOf expression,induce
R9856 T12420 T12418 themeOf expression,induce
R9857 T12391 T12390 themeOf Id1 mRNA,upregulation
R9858 T12421 T12419 themeOf Id2,expression
R9859 T12422 T12420 themeOf Id3,expression
R9860 T12396 T12398 themeOf Id2,expression
R9861 T12397 T12399 themeOf Id3,expression
R9862 T12424 T12425 causeOf Id proteins,inhibitors
R9863 T12398 T12393 themeOf expression,induces
R9864 T12399 T12394 themeOf expression,induces
R9865 T12400 T12395 themeOf expression,induces
R9866 T12401 T12400 themeOf Id1,expression
R9867 T12404 T12403 themeOf Id proteins,regulate
R9868 T12426 T12425 themeOf Pax5,inhibitors
R9869 T12405 T12408 themeOf Id2,expressed
R9870 T12406 T12409 themeOf Id3,expressed
R9871 T12407 T12410 themeOf Id proteins,expressed
R9872 T12430 T12429 themeOf Id1 protein,upregulation
R9873 T12411 T12413 themeOf Id2,expressed
R9874 T12412 T12414 themeOf Id3 protein,expressed
R9875 T12433 T12434 themeOf Id family,overexpressed
R9876 T12416 T12415 themeOf Id1,expressed
R9877 T12434 T12435 themeOf overexpressed,overexpressed
R9878 T12436 T12437 themeOf Id1,overexpressed
R9879 T12438 T12439 themeOf High BMP-6 mRNA,expression
R9880 T12441 T12440 themeOf Id1,expression

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Negation Speculation
T7578 549-550 Protein denotes 5
T7579 551-552 Protein denotes 8
T7580 553-568 Phosphorylation denotes phosphorylation
T7581 553-568 Phosphorylation denotes phosphorylation
T7582 553-568 Phosphorylation denotes phosphorylation
T7583 587-592 Protein denotes BMP-6
T7584 593-600 Positive_regulation denotes induced
T7585 601-605 Protein denotes Smad
T7586 606-621 Phosphorylation denotes phosphorylation
T7587 626-634 Positive_regulation denotes followed
T7588 626-634 Positive_regulation denotes followed
T7589 650-662 Positive_regulation denotes upregulation
T7590 650-662 Positive_regulation denotes upregulation
T7591 666-669 Protein denotes Id1
T7592 690-693 Protein denotes Id1
T7593 770-775 Protein denotes BMP-6
T7594 886-891 Protein denotes BMP-6
T7595 959-965 Protein denotes Noggin
T7596 1009-1015 Protein denotes Noggin
T7597 1034-1039 Protein denotes BMP-6
T7598 1040-1050 Negative_regulation denotes antagonist
T7599 1100-1107 Protein denotes BMP-RIB
T7600 1115-1122 Protein denotes BMP-RII
T7601 1192-1197 Protein denotes BMP-6
T7602 1613-1618 Protein denotes BMP-6
T7603 1680-1685 Protein denotes BMP-2
T7604 1687-1688 Protein denotes 4
T7605 1690-1691 Protein denotes 6
T7606 1696-1698 Protein denotes -7
T7607 1862-1867 Protein denotes BMP-4
T7608 2058-2063 Protein denotes BMP-6
T7609 2207-2214 Gene_expression denotes express
T7610 2207-2214 Gene_expression denotes express
T7611 2207-2214 Gene_expression denotes express
T7612 2207-2214 Gene_expression denotes express
T7613 2240-2247 Protein denotes Act-RIA
T7614 2252-2259 Protein denotes BMP-RIB
T7615 2287-2294 Protein denotes BMP-RII
T7616 2299-2307 Protein denotes Act-RIIb
T7617 2328-2335 Binding denotes binding
T7618 2328-2335 Binding denotes binding
T7619 2328-2335 Binding denotes binding
T7620 2328-2335 Binding denotes binding
T7621 2363-2368 Protein denotes BMP-6
T7622 2397-2402 Protein denotes BMP-6
T7623 2689-2694 Protein denotes BMP-2
T7624 2713-2719 Positive_regulation denotes induce
T7625 2720-2730 Positive_regulation denotes activation
T7626 2734-2739 Protein denotes STAT3
T7627 2833-2838 Protein denotes BMP-2
T7628 2904-2919 Phosphorylation denotes phosphorylation
T7629 2904-2919 Phosphorylation denotes phosphorylation
T7630 2904-2919 Phosphorylation denotes phosphorylation
T7631 2904-2919 Phosphorylation denotes phosphorylation
T7632 2928-2933 Protein denotes STAT3
T7633 2938-2943 Protein denotes Smad1
T7634 2944-2945 Protein denotes 5
T7635 2946-2947 Protein denotes 8
T7636 3145-3150 Protein denotes BMP-6
T7637 3151-3158 Positive_regulation denotes induced true
T7638 3159-3166 Regulation denotes changes
T7639 3174-3189 Phosphorylation denotes phosphorylation
T7640 3200-3205 Protein denotes STAT3
T7641 3270-3285 Phosphorylation denotes phosphorylation
T7642 3270-3285 Phosphorylation denotes phosphorylation
T7643 3270-3285 Phosphorylation denotes phosphorylation
T7644 3289-3294 Protein denotes Smad1
T7645 3295-3296 Protein denotes 5
T7646 3297-3298 Protein denotes 8
T7647 3369-3376 Positive_regulation denotes induced
T7648 3369-3376 Positive_regulation denotes induced
T7649 3369-3376 Positive_regulation denotes induced
T7650 3377-3392 Phosphorylation denotes phosphorylation
T7651 3377-3392 Phosphorylation denotes phosphorylation
T7652 3377-3392 Phosphorylation denotes phosphorylation
T7653 3396-3401 Protein denotes Smad1
T7654 3402-3403 Protein denotes 5
T7655 3404-3405 Protein denotes 8
T7656 3613-3625 Positive_regulation denotes Upregulation
T7657 3613-3625 Positive_regulation denotes Upregulation
T7658 3613-3625 Positive_regulation denotes Upregulation
T7659 3629-3632 Protein denotes Id1
T7660 3637-3642 Protein denotes Smad1
T7661 3643-3644 Protein denotes 5
T7662 3645-3646 Protein denotes 8
T7663 3647-3662 Phosphorylation denotes phosphorylation
T7664 3647-3662 Phosphorylation denotes phosphorylation
T7665 3647-3662 Phosphorylation denotes phosphorylation
T7666 3674-3683 Regulation denotes mechanism
T7667 3674-3683 Regulation denotes mechanism
T7668 3674-3683 Regulation denotes mechanism
T7669 3688-3693 Protein denotes BMP-6
T7670 3912-3924 Positive_regulation denotes upregulation
T7671 3929-3932 Protein denotes Id1
T7672 3936-3941 Protein denotes BMP-6
T7673 3969-3975 Gene_expression denotes amount
T7674 3969-3975 Gene_expression denotes amount
T7675 3979-3982 Protein denotes Id2
T7676 3983-3986 Protein denotes Id4
T7677 3987-4005 Positive_regulation denotes remained unchanged true
T7678 3987-4005 Positive_regulation denotes remained unchanged true
T7679 4069-4081 Positive_regulation denotes upregulation
T7680 4085-4088 Protein denotes Id1
T7681 4108-4114 Gene_expression denotes amount
T7682 4108-4114 Gene_expression denotes amount
T7683 4118-4121 Protein denotes Id2
T7684 4126-4129 Protein denotes Id3
T7685 4145-4163 Positive_regulation denotes remained unchanged true
T7686 4145-4163 Positive_regulation denotes remained unchanged true
T7687 4177-4180 Protein denotes Id1
T7688 4211-4220 Gene_expression denotes expressed true true
T7689 4298-4308 Gene_expression denotes expression
T7690 4419-4431 Positive_regulation denotes upregulation
T7691 4435-4438 Protein denotes Id1
T7692 4553-4558 Protein denotes TGF-β
T7693 4598-4605 Positive_regulation denotes induces
T7694 4598-4605 Positive_regulation denotes induces true
T7695 4598-4605 Positive_regulation denotes induces
T7696 4611-4614 Protein denotes Id2
T7697 4619-4622 Protein denotes Id3
T7698 4623-4633 Gene_expression denotes expression
T7699 4623-4633 Gene_expression denotes expression
T7700 4651-4654 Protein denotes Id1
T7701 4735-4740 Protein denotes TGF-β
T7702 4782-4785 Protein denotes Id2
T7703 4790-4793 Protein denotes Id3
T7704 4838-4847 Gene_expression denotes expressed true
T7705 4838-4847 Gene_expression denotes expressed true
T7706 4901-4904 Protein denotes Id2
T7707 4909-4912 Protein denotes Id3
T7708 4950-4959 Gene_expression denotes expressed
T7709 4950-4959 Gene_expression denotes expressed
T7710 4950-4959 Gene_expression denotes expressed
T7711 4965-4968 Protein denotes Id1
T7712 4998-5003 Protein denotes BMP-6
T7713 5012-5018 Positive_regulation denotes induce true
T7714 5012-5018 Positive_regulation denotes induce true
T7715 5031-5038 Regulation denotes changes
T7716 5031-5038 Regulation denotes changes
T7717 5054-5064 Gene_expression denotes expression
T7718 5054-5064 Gene_expression denotes expression
T7719 5068-5071 Protein denotes Id2
T7720 5076-5079 Protein denotes Id3
T7721 5229-5239 Negative_regulation denotes inhibitors
T7722 5258-5262 Protein denotes Pax5
T7723 5275-5289 Binding denotes forming dimers
T7724 5311-5317 Positive_regulation denotes making
T7725 5333-5337 Binding denotes bind true
T7726 5399-5403 Protein denotes Pax5
T7727 5693-5698 Protein denotes BMP-6
T7728 5727-5739 Positive_regulation denotes upregulation
T7729 5743-5746 Protein denotes Id1
T7730 5900-5905 Protein denotes TGF-β
T7731 6171-6174 Protein denotes Id1
T7732 6219-6232 Positive_regulation denotes overexpressed true
T7733 6342-6347 Protein denotes BMP-6
T7734 6493-6497 Positive_regulation denotes High
T7735 6498-6503 Protein denotes BMP-6
T7736 6504-6519 Transcription denotes mRNA expression
T7737 6636-6646 Gene_expression denotes expression
T7738 6650-6653 Protein denotes Id1
T7739 6794-6799 Protein denotes BMP-6
T7740 6875-6883 Positive_regulation denotes elevated
T7741 6875-6883 Positive_regulation denotes elevated
T7742 6884-6890 Gene_expression denotes levels
T7743 6884-6890 Gene_expression denotes levels
T7744 6894-6897 Protein denotes Id1
T7745 6902-6905 Protein denotes Id3
T7746 7183-7187 Protein denotes Id-1
T7747 7218-7222 Positive_regulation denotes over
T7748 7223-7233 Gene_expression denotes expression
T7749 7237-7247 Negative_regulation denotes inhibition
T7750 7251-7255 Protein denotes Id-1
T7751 7261-7271 Gene_expression denotes expression
T7763 7881-7886 Protein denotes BMP-6
T7764 7926-7936 Transcription denotes expression true
T7765 7937-7942 Protein denotes BMP-6
T7766 8014-8026 Positive_regulation denotes upregulation
T7767 8041-8046 Protein denotes BMP-6
T7768 8166-8171 Protein denotes BMP-6
T7769 8338-8345 Transcription denotes express
T7770 8346-8351 Protein denotes BMP-6
T7771 8457-8465 Gene_expression denotes detected true
T7772 8466-8471 Protein denotes BMP-6
T7773 8547-8552 Protein denotes BMP-6
T7774 8553-8563 Gene_expression denotes production true
T7775 8629-8639 Gene_expression denotes production
T7776 8643-8648 Protein denotes BMP-6
T7777 8830-8842 Positive_regulation denotes upregulation
T7778 8850-8855 Protein denotes BMP-6
T7779 8939-8944 Protein denotes TGF-β
T7780 9180-9185 Protein denotes BMP-6
T7781 9336-9341 Protein denotes TGF-β
T7782 9368-9374 Protein denotes TGF-β1
T7783 9379-9384 Protein denotes BMP-4
T7784 9509-9521 Positive_regulation denotes upregulation
T7785 9525-9530 Protein denotes BMP-6
T7786 9574-9580 Transcription denotes detect true
T7787 9581-9586 Protein denotes BMP-6
T7788 9625-9628 Protein denotes CD4
T7789 9633-9636 Protein denotes CD8
T7790 9679-9682 Protein denotes CD3
T7791 9692-9696 Protein denotes CD28
T7792 9807-9812 Protein denotes BMP-6
T7793 9973-9978 Protein denotes BMP-6
T7794 9979-9989 Gene_expression denotes production
T7795 10121-10127 Positive_regulation denotes highly
T7796 10128-10135 Transcription denotes express
T7797 10136-10141 Protein denotes BMP-6
T7798 10199-10206 Gene_expression denotes produce
T7799 10207-10212 Protein denotes BMP-6
T7800 10256-10261 Protein denotes BMP-6
T7801 10304-10309 Protein denotes BMP-6
T7802 10324-10336 Transcription denotes demonstrated true
T7803 10513-10521 Transcription denotes negative true
T7804 10530-10535 Protein denotes BMP-6
T7805 10606-10611 Protein denotes BMP-6
T7806 10612-10622 Gene_expression denotes production true true
T7566 328-333 Protein denotes BMP-6
T7567 354-358 Protein denotes CD19
T7568 383-388 Protein denotes BMP-6
T7569 411-415 Protein denotes CD27
T7570 497-502 Protein denotes BMP-6
T7571 503-510 Positive_regulation denotes induced
T7572 503-510 Positive_regulation denotes induced
T7573 503-510 Positive_regulation denotes induced
T7574 530-538 Positive_regulation denotes increase
T7575 530-538 Positive_regulation denotes increase
T7576 530-538 Positive_regulation denotes increase
T7577 542-548 Protein denotes Smad-1
T7752 7291-7296 Protein denotes BMP-6
T7753 7358-7363 Protein denotes BMP-6
T7754 7364-7373 Gene_expression denotes producing
T7755 7514-7518 Positive_regulation denotes High
T7756 7519-7524 Protein denotes BMP-6
T7757 7525-7540 Transcription denotes mRNA expression
T7758 7616-7626 Transcription denotes production
T7759 7630-7635 Protein denotes BMP-6
T7760 7720-7729 Regulation denotes autocrine
T7761 7730-7735 Protein denotes BMP-6
T7762 7871-7880 Regulation denotes autocrine true
R5822 T7570 T7572 causeOf BMP-6,induced
R5823 T7570 T7571 causeOf BMP-6,induced
R5824 T7570 T7573 causeOf BMP-6,induced
R5825 T7574 T7573 themeOf increase,induced
R5826 T7575 T7571 themeOf increase,induced
R5827 T7576 T7572 themeOf increase,induced
R5828 T7577 T7580 themeOf Smad-1,phosphorylation
R5829 T7578 T7582 themeOf 5,phosphorylation
R5830 T7579 T7581 themeOf 8,phosphorylation
R5831 T7580 T7576 themeOf phosphorylation,increase
R5832 T7581 T7574 themeOf phosphorylation,increase
R5833 T7582 T7575 themeOf phosphorylation,increase
R5834 T7583 T7584 causeOf BMP-6,induced
R5835 T7585 T7586 themeOf Smad,phosphorylation
R5836 T7586 T7584 themeOf phosphorylation,induced
R5837 T7586 T7587 causeOf phosphorylation,followed
R5838 T7586 T7588 causeOf phosphorylation,followed
R5839 T7589 T7587 themeOf upregulation,followed
R5840 T7590 T7588 themeOf upregulation,followed
R5841 T7591 T7589 themeOf Id1,upregulation
R5842 T7592 T7590 themeOf Id1,upregulation
R5843 T7596 T7598 causeOf Noggin,antagonist
R5844 T7597 T7598 themeOf BMP-6,antagonist
R5845 T7613 T7611 themeOf Act-RIA,express
R5846 T7613 T7620 themeOf Act-RIA,binding
R5847 T7614 T7609 themeOf BMP-RIB,express
R5848 T7614 T7618 themeOf BMP-RIB,binding
R5849 T7615 T7610 themeOf BMP-RII,express
R5850 T7615 T7619 themeOf BMP-RII,binding
R5851 T7616 T7612 themeOf Act-RIIb,express
R5852 T7616 T7617 themeOf Act-RIIb,binding
R5853 T7621 T7620 themeOf BMP-6,binding
R5854 T7621 T7618 themeOf BMP-6,binding
R5855 T7621 T7619 themeOf BMP-6,binding
R5856 T7621 T7617 themeOf BMP-6,binding
R5857 T7623 T7624 causeOf BMP-2,induce
R5858 T7625 T7624 themeOf activation,induce
R5859 T7626 T7625 themeOf STAT3,activation
R5860 T7632 T7630 themeOf STAT3,phosphorylation
R5861 T7633 T7629 themeOf Smad1,phosphorylation
R5862 T7634 T7628 themeOf 5,phosphorylation
R5863 T7635 T7631 themeOf 8,phosphorylation
R5864 T7636 T7637 causeOf BMP-6,induced
R5865 T7638 T7637 themeOf changes,induced
R5866 T7639 T7638 themeOf phosphorylation,changes
R5867 T7640 T7639 themeOf STAT3,phosphorylation
R5868 T7644 T7642 themeOf Smad1,phosphorylation
R5869 T7645 T7643 themeOf 5,phosphorylation
R5870 T7646 T7641 themeOf 8,phosphorylation
R5871 T7650 T7648 themeOf phosphorylation,induced
R5872 T7651 T7649 themeOf phosphorylation,induced
R5873 T7652 T7647 themeOf phosphorylation,induced
R5874 T7653 T7650 themeOf Smad1,phosphorylation
R5875 T7654 T7651 themeOf 5,phosphorylation
R5876 T7655 T7652 themeOf 8,phosphorylation
R5880 T7659 T7658 themeOf Id1,Upregulation
R5886 T7663 T7656 causeOf phosphorylation,Upregulation
R5887 T7664 T7657 causeOf phosphorylation,Upregulation
R5888 T7665 T7658 causeOf phosphorylation,Upregulation
R5889 T7669 T7666 causeOf BMP-6,mechanism
R5890 T7669 T7667 causeOf BMP-6,mechanism
R5891 T7669 T7668 causeOf BMP-6,mechanism
R5892 T7671 T7670 themeOf Id1,upregulation
R5893 T7672 T7670 causeOf BMP-6,upregulation
R5894 T7672 T7677 causeOf BMP-6,remained unchanged
R5895 T7672 T7678 causeOf BMP-6,remained unchanged
R5896 T7673 T7678 themeOf amount,remained unchanged
R5897 T7674 T7677 themeOf amount,remained unchanged
R5898 T7675 T7674 themeOf Id2,amount
R5899 T7676 T7673 themeOf Id4,amount
R5900 T7680 T7679 themeOf Id1,upregulation
R5901 T7681 T7686 themeOf amount,remained unchanged
R5902 T7682 T7685 themeOf amount,remained unchanged
R5903 T7683 T7682 themeOf Id2,amount
R5904 T7684 T7681 themeOf Id3,amount
R5905 T7687 T7688 themeOf Id1,expressed
R5906 T7687 T7689 themeOf Id1,expression
R5938 T7742 T7741 themeOf levels,elevated
R5939 T7743 T7740 themeOf levels,elevated
R5940 T7744 T7742 themeOf Id1,levels
R5941 T7745 T7743 themeOf Id3,levels
R5942 T7748 T7747 themeOf expression,over
R5943 T7750 T7748 themeOf Id-1,expression
R5944 T7750 T7751 themeOf Id-1,expression
R5945 T7751 T7749 themeOf expression,inhibition
R5946 T7753 T7754 themeOf BMP-6,producing
R5947 T7756 T7757 themeOf BMP-6,mRNA expression
R5948 T7757 T7755 themeOf mRNA expression,High
R5949 T7759 T7758 themeOf BMP-6,production
R5950 T7761 T7760 themeOf BMP-6,autocrine
R5951 T7761 T7760 causeOf BMP-6,autocrine
R5952 T7763 T7762 themeOf BMP-6,autocrine
R5953 T7763 T7762 causeOf BMP-6,autocrine
R5954 T7765 T7764 themeOf BMP-6,expression
R5955 T7767 T7766 themeOf BMP-6,upregulation
R5956 T7770 T7769 themeOf BMP-6,express
R5957 T7772 T7771 themeOf BMP-6,detected
R5958 T7773 T7774 themeOf BMP-6,production
R5959 T7776 T7775 themeOf BMP-6,production
R5960 T7778 T7777 themeOf BMP-6,upregulation
R5961 T7785 T7784 themeOf BMP-6,upregulation
R5962 T7787 T7786 themeOf BMP-6,detect
R5963 T7793 T7794 themeOf BMP-6,production
R5964 T7796 T7795 themeOf express,highly
R5965 T7797 T7796 themeOf BMP-6,express
R5966 T7799 T7798 themeOf BMP-6,produce
R5967 T7801 T7802 themeOf BMP-6,demonstrated
R5968 T7804 T7803 themeOf BMP-6,negative
R5969 T7805 T7806 themeOf BMP-6,production
R5907 T7691 T7690 themeOf Id1,upregulation
R5908 T7696 T7699 themeOf Id2,expression
R5909 T7697 T7698 themeOf Id3,expression
R5910 T7698 T7695 themeOf expression,induces
R5911 T7699 T7693 themeOf expression,induces
R5912 T7700 T7694 themeOf Id1,induces
R5913 T7702 T7705 themeOf Id2,expressed
R5914 T7703 T7704 themeOf Id3,expressed
R5915 T7706 T7710 themeOf Id2,expressed
R5916 T7707 T7708 themeOf Id3,expressed
R5917 T7711 T7709 themeOf Id1,expressed
R5918 T7712 T7713 causeOf BMP-6,induce
R5919 T7712 T7714 causeOf BMP-6,induce
R5920 T7715 T7713 themeOf changes,induce
R5921 T7716 T7714 themeOf changes,induce
R5922 T7717 T7715 themeOf expression,changes
R5923 T7718 T7716 themeOf expression,changes
R5924 T7719 T7717 themeOf Id2,expression
R5925 T7720 T7718 themeOf Id3,expression
R5926 T7722 T7721 themeOf Pax5,inhibitors
R5927 T7722 T7723 themeOf Pax5,forming dimers
R5928 T7722 T7725 themeOf Pax5,bind
R5929 T7723 T7721 causeOf forming dimers,inhibitors
R5930 T7723 T7724 causeOf forming dimers,making
R5931 T7725 T7724 themeOf bind,making
R5932 T7727 T7728 causeOf BMP-6,upregulation
R5933 T7729 T7728 themeOf Id1,upregulation
R5934 T7731 T7732 themeOf Id1,overexpressed
R5935 T7735 T7736 themeOf BMP-6,mRNA expression
R5936 T7736 T7734 themeOf mRNA expression,High
R5937 T7738 T7737 themeOf Id1,expression
R5877 T7656 T7667 themeOf Upregulation,mechanism
R5878 T7657 T7668 themeOf Upregulation,mechanism
R5879 T7658 T7666 themeOf Upregulation,mechanism
R5881 T7659 T7656 themeOf Id1,Upregulation
R5882 T7659 T7657 themeOf Id1,Upregulation
R5883 T7660 T7665 themeOf Smad1,phosphorylation
R5884 T7661 T7663 themeOf 5,phosphorylation
R5885 T7662 T7664 themeOf 8,phosphorylation

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T9860 770-773 P22004 denotes BMP
T9861 770-773 P12643 denotes BMP
T9862 770-773 P12644 denotes BMP
T9863 770-775 P22004 denotes BMP-6
T9864 886-889 P12643 denotes BMP
T9865 886-889 P12644 denotes BMP
T9866 886-889 P22004 denotes BMP
T9867 886-889 P18075 denotes BMP
T9868 886-891 P22004 denotes BMP-6
T9869 959-965 Q13253 denotes Noggin
T9870 1009-1015 Q13253 denotes Noggin
T9871 1034-1037 P18075 denotes BMP
T9872 1034-1037 P12644 denotes BMP
T9873 1034-1037 P12643 denotes BMP
T9874 1034-1037 P22004 denotes BMP
T9875 1034-1039 P22004 denotes BMP-6
T9876 1100-1103 P12644 denotes BMP
T9877 1100-1103 P12643 denotes BMP
T9878 1100-1103 P22004 denotes BMP
T9879 1100-1103 P18075 denotes BMP
T9880 1100-1107 O00238 denotes BMP-RIB
T9881 1115-1118 P12643 denotes BMP
T9882 1115-1118 P22004 denotes BMP
T9883 1115-1118 P18075 denotes BMP
T9884 1115-1118 P12644 denotes BMP
T9885 1115-1122 Q13873 denotes BMP-RII
T9886 1192-1195 P12644 denotes BMP
T9887 1192-1195 P22004 denotes BMP
T9888 1192-1195 P12643 denotes BMP
T9889 1192-1195 P18075 denotes BMP
T9890 1192-1197 P22004 denotes BMP-6
T9891 1317-1321 P18075 denotes BMPs
T9892 1317-1321 P12644 denotes BMPs
T9893 1317-1321 P12643 denotes BMPs
T9894 1317-1321 P22004 denotes BMPs
T9895 1346-1350 P18075 denotes BMPs
T9896 1346-1350 P12643 denotes BMPs
T9897 1346-1350 P12644 denotes BMPs
T9898 1346-1350 P22004 denotes BMPs
T9899 1613-1616 P22004 denotes BMP
T9900 1613-1616 P12644 denotes BMP
T9901 1613-1616 P12643 denotes BMP
T9902 1613-1616 P18075 denotes BMP
T9903 1613-1618 P22004 denotes BMP-6
T9904 1680-1683 P22004 denotes BMP
T9905 1680-1683 P12644 denotes BMP
T9906 1680-1683 P12643 denotes BMP
T9907 1680-1683 P18075 denotes BMP
T9908 1680-1685 P12643 denotes BMP-2
T9909 1751-1754 P12644 denotes BMP
T9910 1751-1754 P22004 denotes BMP
T9911 1751-1754 P12643 denotes BMP
T9912 1751-1754 P18075 denotes BMP
T9913 1862-1865 P12644 denotes BMP
T9914 1862-1865 P22004 denotes BMP
T9915 1862-1865 P12643 denotes BMP
T9916 1862-1865 P18075 denotes BMP
T9917 1862-1867 P12644 denotes BMP-4
T9918 1958-1962 P12644 denotes BMPs
T9919 1958-1962 P12643 denotes BMPs
T9920 1958-1962 P18075 denotes BMPs
T9921 1958-1962 P22004 denotes BMPs
T9922 2058-2061 P12643 denotes BMP
T9923 2058-2061 P18075 denotes BMP
T9924 2058-2061 P12644 denotes BMP
T9925 2058-2061 P22004 denotes BMP
T9926 2058-2063 P22004 denotes BMP-6
T9927 2118-2121 P12643 denotes BMP
T9928 2118-2121 P22004 denotes BMP
T9929 2118-2121 P12644 denotes BMP
T9930 2118-2121 P18075 denotes BMP
T9931 2219-2222 P12644 denotes BMP
T9932 2219-2222 P18075 denotes BMP
T9933 2219-2222 P12643 denotes BMP
T9934 2219-2222 P22004 denotes BMP
T9935 2219-2239 Q13873 denotes BMP type I receptors
T9936 2240-2247 Q04771 denotes Act-RIA
T9937 2252-2255 P18075 denotes BMP
T9938 2252-2255 P22004 denotes BMP
T9939 2252-2255 P12643 denotes BMP
T9940 2252-2255 P12644 denotes BMP
T9941 2252-2259 O00238 denotes BMP-RIB
T9942 2287-2290 P18075 denotes BMP
T9943 2287-2290 P12643 denotes BMP
T9944 2287-2290 P22004 denotes BMP
T9945 2287-2290 P12644 denotes BMP
T9946 2287-2294 Q13873 denotes BMP-RII
T9947 2299-2307 Q13705 denotes Act-RIIb
T9948 2347-2351 P18075 denotes BMPs
T9949 2347-2351 P22004 denotes BMPs
T9950 2347-2351 P12644 denotes BMPs
T9951 2347-2351 P12643 denotes BMPs
T9952 2363-2366 P18075 denotes BMP
T9953 2363-2366 P22004 denotes BMP
T9954 2363-2366 P12644 denotes BMP
T9955 2363-2366 P12643 denotes BMP
T9956 2363-2368 P22004 denotes BMP-6
T9957 2397-2400 P22004 denotes BMP
T9958 2397-2400 P12644 denotes BMP
T9959 2397-2400 P12643 denotes BMP
T9960 2397-2400 P18075 denotes BMP
T9961 2397-2402 P22004 denotes BMP-6
T9962 2562-2566 P22004 denotes BMPs
T9963 2562-2566 P18075 denotes BMPs
T9964 2562-2566 P12644 denotes BMPs
T9965 2562-2566 P12643 denotes BMPs
T9966 2689-2692 P12644 denotes BMP
T9967 2689-2692 P18075 denotes BMP
T9968 2689-2692 P12643 denotes BMP
T9969 2689-2692 P22004 denotes BMP
T9970 2689-2694 P12643 denotes BMP-2
T9971 2734-2739 P40763 denotes STAT3
T9972 2833-2836 P22004 denotes BMP
T9973 2833-2836 P18075 denotes BMP
T9974 2833-2836 P12644 denotes BMP
T9975 2833-2836 P12643 denotes BMP
T9976 2833-2838 P12643 denotes BMP-2
T9977 2888-2891 O15264 denotes p38
T9978 2888-2891 P53778 denotes p38
T9979 2888-2891 Q15759 denotes p38
T9980 2888-2891 Q16539 denotes p38
T9981 2923-2926 Q16539 denotes p38
T9982 2923-2926 P53778 denotes p38
T9983 2923-2926 O15264 denotes p38
T9984 2923-2926 Q15759 denotes p38
T9985 2928-2933 P40763 denotes STAT3
T9986 2938-2943 Q15797 denotes Smad1
T9987 2968-2971 P18075 denotes BMP
T9988 2968-2971 P22004 denotes BMP
T9989 2968-2971 P12644 denotes BMP
T9990 2968-2971 P12643 denotes BMP
T9991 3021-3025 P22004 denotes BMPs
T9992 3021-3025 P12644 denotes BMPs
T9993 3021-3025 P12643 denotes BMPs
T9994 3021-3025 P18075 denotes BMPs
T9995 3130-3134 P00519 denotes able
T9996 3145-3148 P12644 denotes BMP
T9997 3145-3148 P22004 denotes BMP
T9998 3145-3148 P18075 denotes BMP
T9999 3145-3148 P12643 denotes BMP
T10000 3145-3150 P22004 denotes BMP-6
T10001 3200-3205 P40763 denotes STAT3
T10002 3209-3212 P53778 denotes p38
T10003 3209-3212 Q16539 denotes p38
T10004 3209-3212 Q15759 denotes p38
T10005 3209-3212 O15264 denotes p38
T10006 3289-3294 Q15797 denotes Smad1
T10007 3359-3363 P22004 denotes BMPs
T10008 3359-3363 P12644 denotes BMPs
T10009 3359-3363 P12643 denotes BMPs
T10010 3359-3363 P18075 denotes BMPs
T10011 3396-3401 Q15797 denotes Smad1
T10012 3590-3594 P18075 denotes BMPs
T10013 3590-3594 P12644 denotes BMPs
T10014 3590-3594 P22004 denotes BMPs
T10015 3590-3594 P12643 denotes BMPs
T10016 3629-3632 P41134 denotes Id1
T10017 3637-3642 Q15797 denotes Smad1
T10018 3688-3691 P22004 denotes BMP
T10019 3688-3691 P18075 denotes BMP
T10020 3688-3691 P12643 denotes BMP
T10021 3688-3691 P12644 denotes BMP
T10022 3688-3693 P22004 denotes BMP-6
T10023 3753-3755 P41134 denotes Id
T10024 3929-3932 P41134 denotes Id1
T10025 3936-3939 P18075 denotes BMP
T10026 3936-3939 P12643 denotes BMP
T10027 3936-3939 P22004 denotes BMP
T10028 3936-3939 P12644 denotes BMP
T10029 3936-3941 P22004 denotes BMP-6
T10030 3979-3982 Q02363 denotes Id2
T10031 3983-3986 P47928 denotes Id4
T10032 4085-4088 P41134 denotes Id1
T10033 4118-4121 Q02363 denotes Id2
T10034 4126-4129 Q02535 denotes Id3
T10035 4177-4180 P41134 denotes Id1
T10036 4435-4438 P41134 denotes Id1
T10037 4553-4558 P01137 denotes TGF-β
T10038 4611-4614 Q02363 denotes Id2
T10039 4619-4622 Q02535 denotes Id3
T10040 4651-4654 P41134 denotes Id1
T10041 4735-4740 P01137 denotes TGF-β
T10042 4757-4759 P41134 denotes Id
T10043 4782-4785 Q02363 denotes Id2
T10044 4790-4793 Q02535 denotes Id3
T10045 4819-4821 P41134 denotes Id
T10046 4901-4904 Q02363 denotes Id2
T10047 4909-4912 Q02535 denotes Id3
T10048 4965-4968 P41134 denotes Id1
T10049 4998-5001 P12643 denotes BMP
T10050 4998-5001 P18075 denotes BMP
T10051 4998-5001 P12644 denotes BMP
T10052 4998-5001 P22004 denotes BMP
T10053 4998-5003 P22004 denotes BMP-6
T10054 5068-5071 Q02363 denotes Id2
T10055 5076-5079 Q02535 denotes Id3
T10056 5101-5103 P41134 denotes Id
T10057 5192-5194 P41134 denotes Id
T10058 5258-5262 Q02548 denotes Pax5
T10059 5399-5403 Q02548 denotes Pax5
T10060 5408-5410 P41134 denotes Id
T10061 5693-5696 P12643 denotes BMP
T10062 5693-5696 P18075 denotes BMP
T10063 5693-5696 P22004 denotes BMP
T10064 5693-5696 P12644 denotes BMP
T10065 5693-5698 P22004 denotes BMP-6
T10066 5743-5746 P41134 denotes Id1
T10067 5795-5797 P41134 denotes Id
T10068 5900-5905 P01137 denotes TGF-β
T10069 5925-5927 P41134 denotes Id
T10070 6100-6102 P41134 denotes Id
T10071 6171-6174 P41134 denotes Id1
T10072 6342-6345 P18075 denotes BMP
T10073 6342-6345 P22004 denotes BMP
T10074 6342-6345 P12643 denotes BMP
T10075 6342-6345 P12644 denotes BMP
T10076 6342-6347 P22004 denotes BMP-6
T10077 6498-6501 P12643 denotes BMP
T10078 6498-6501 P12644 denotes BMP
T10079 6498-6501 P22004 denotes BMP
T10080 6498-6501 P18075 denotes BMP
T10081 6498-6503 P22004 denotes BMP-6
T10082 6650-6653 P41134 denotes Id1
T10083 6794-6797 P22004 denotes BMP
T10084 6794-6797 P18075 denotes BMP
T10085 6794-6797 P12644 denotes BMP
T10086 6794-6797 P12643 denotes BMP
T10087 6794-6799 P22004 denotes BMP-6
T10088 6894-6897 P41134 denotes Id1
T10089 6902-6905 Q02535 denotes Id3
T10090 7015-7017 P41134 denotes Id
T10091 7183-7185 P41134 denotes Id
T10092 7251-7253 P41134 denotes Id
T10093 7291-7294 P12643 denotes BMP
T10094 7291-7294 P18075 denotes BMP
T10095 7291-7294 P22004 denotes BMP
T10096 7291-7294 P12644 denotes BMP
T10097 7291-7296 P22004 denotes BMP-6
T10098 7358-7361 P22004 denotes BMP
T10099 7358-7361 P12643 denotes BMP
T10100 7358-7361 P18075 denotes BMP
T10101 7358-7361 P12644 denotes BMP
T10102 7358-7363 P22004 denotes BMP-6
T10103 7519-7522 P12643 denotes BMP
T10104 7519-7522 P12644 denotes BMP
T10105 7519-7522 P22004 denotes BMP
T10106 7519-7522 P18075 denotes BMP
T10107 7519-7524 P22004 denotes BMP-6
T10108 7630-7633 P12644 denotes BMP
T10109 7630-7633 P18075 denotes BMP
T10110 7630-7633 P12643 denotes BMP
T10111 7630-7633 P22004 denotes BMP
T10112 7630-7635 P22004 denotes BMP-6
T10113 7730-7733 P12643 denotes BMP
T10114 7730-7733 P12644 denotes BMP
T10115 7730-7733 P22004 denotes BMP
T10116 7730-7733 P18075 denotes BMP
T10117 7730-7735 P22004 denotes BMP-6
T10118 7881-7884 P12644 denotes BMP
T10119 7881-7884 P12643 denotes BMP
T10120 7881-7884 P18075 denotes BMP
T10121 7881-7884 P22004 denotes BMP
T10122 7881-7886 P22004 denotes BMP-6
T10123 7937-7940 P22004 denotes BMP
T10124 7937-7940 P12643 denotes BMP
T10125 7937-7940 P18075 denotes BMP
T10126 7937-7940 P12644 denotes BMP
T10127 7937-7942 P22004 denotes BMP-6
T10128 8041-8044 P22004 denotes BMP
T10129 8041-8044 P12643 denotes BMP
T10130 8041-8044 P12644 denotes BMP
T10131 8041-8044 P18075 denotes BMP
T10132 8041-8046 P22004 denotes BMP-6
T10133 8166-8169 P18075 denotes BMP
T10134 8166-8169 P12644 denotes BMP
T10135 8166-8169 P12643 denotes BMP
T10136 8166-8169 P22004 denotes BMP
T10137 8166-8171 P22004 denotes BMP-6
T10138 8257-8260 P12643 denotes BMP
T10139 8257-8260 P18075 denotes BMP
T10140 8257-8260 P22004 denotes BMP
T10141 8257-8260 P12644 denotes BMP
T10142 8257-8262 P22004 denotes BMP-6
T10143 8346-8349 P18075 denotes BMP
T10144 8346-8349 P12643 denotes BMP
T10145 8346-8349 P12644 denotes BMP
T10146 8346-8349 P22004 denotes BMP
T10147 8346-8351 P22004 denotes BMP-6
T10148 8466-8469 P18075 denotes BMP
T10149 8466-8469 P22004 denotes BMP
T10150 8466-8469 P12643 denotes BMP
T10151 8466-8469 P12644 denotes BMP
T10152 8466-8471 P22004 denotes BMP-6
T10153 8547-8550 P22004 denotes BMP
T10154 8547-8550 P18075 denotes BMP
T10155 8547-8550 P12644 denotes BMP
T10156 8547-8550 P12643 denotes BMP
T10157 8547-8552 P22004 denotes BMP-6
T10158 8643-8646 P12643 denotes BMP
T10159 8643-8646 P12644 denotes BMP
T10160 8643-8646 P22004 denotes BMP
T10161 8643-8646 P18075 denotes BMP
T10162 8643-8648 P22004 denotes BMP-6
T10163 8764-8768 P18075 denotes BMPs
T10164 8764-8768 P12644 denotes BMPs
T10165 8764-8768 P22004 denotes BMPs
T10166 8764-8768 P12643 denotes BMPs
T10167 8850-8853 P22004 denotes BMP
T10168 8850-8853 P12643 denotes BMP
T10169 8850-8853 P18075 denotes BMP
T10170 8850-8853 P12644 denotes BMP
T10171 8850-8855 P22004 denotes BMP-6
T10172 8939-8944 P01137 denotes TGF-β
T10173 9103-9107 P12644 denotes BMPs
T10174 9103-9107 P12643 denotes BMPs
T10175 9103-9107 P22004 denotes BMPs
T10176 9103-9107 P18075 denotes BMPs
T10177 9180-9183 P18075 denotes BMP
T10178 9180-9183 P12643 denotes BMP
T10179 9180-9183 P22004 denotes BMP
T10180 9180-9183 P12644 denotes BMP
T10181 9180-9185 P22004 denotes BMP-6
T10182 9336-9341 P01137 denotes TGF-β
T10183 9379-9382 P12643 denotes BMP
T10184 9379-9382 P22004 denotes BMP
T10185 9379-9382 P18075 denotes BMP
T10186 9379-9382 P12644 denotes BMP
T10187 9379-9384 P12644 denotes BMP-4
T10188 9431-9434 P12643 denotes BMP
T10189 9431-9434 P12644 denotes BMP
T10190 9431-9434 P18075 denotes BMP
T10191 9431-9434 P22004 denotes BMP
T10192 9525-9528 P22004 denotes BMP
T10193 9525-9528 P18075 denotes BMP
T10194 9525-9528 P12643 denotes BMP
T10195 9525-9528 P12644 denotes BMP
T10196 9525-9530 P22004 denotes BMP-6
T10197 9566-9570 P00519 denotes able
T10198 9581-9584 P12643 denotes BMP
T10199 9581-9584 P12644 denotes BMP
T10200 9581-9584 P18075 denotes BMP
T10201 9581-9584 P22004 denotes BMP
T10202 9581-9586 P22004 denotes BMP-6
T10203 9625-9628 P01730 denotes CD4
T10204 9633-9636 P01732 denotes CD8
T10205 9633-9636 P10966 denotes CD8
T10206 9679-9682 P07766 denotes CD3
T10207 9679-9682 P20963 denotes CD3
T10208 9679-9682 P04234 denotes CD3
T10209 9679-9682 P09693 denotes CD3
T10210 9692-9696 P10747 denotes CD28
T10211 9807-9810 P12643 denotes BMP
T10212 9807-9810 P12644 denotes BMP
T10213 9807-9810 P22004 denotes BMP
T10214 9807-9810 P18075 denotes BMP
T10215 9807-9812 P22004 denotes BMP-6
T10216 9973-9976 P12644 denotes BMP
T10217 9973-9976 P12643 denotes BMP
T10218 9973-9976 P22004 denotes BMP
T10219 9973-9976 P18075 denotes BMP
T10220 9973-9978 P22004 denotes BMP-6
T10221 10136-10139 P12644 denotes BMP
T10222 10136-10139 P12643 denotes BMP
T10223 10136-10139 P22004 denotes BMP
T10224 10136-10139 P18075 denotes BMP
T10225 10136-10141 P22004 denotes BMP-6
T10226 10207-10210 P12643 denotes BMP
T10227 10207-10210 P12644 denotes BMP
T10228 10207-10210 P18075 denotes BMP
T10229 10207-10210 P22004 denotes BMP
T10230 10207-10212 P22004 denotes BMP-6
T10231 10256-10259 P12643 denotes BMP
T10232 10256-10259 P12644 denotes BMP
T10233 10256-10259 P22004 denotes BMP
T10234 10256-10259 P18075 denotes BMP
T10235 10256-10261 P22004 denotes BMP-6
T10236 10304-10307 P22004 denotes BMP
T10237 10304-10307 P12643 denotes BMP
T10238 10304-10307 P18075 denotes BMP
T10239 10304-10307 P12644 denotes BMP
T10240 10304-10309 P22004 denotes BMP-6
T10241 10530-10533 P18075 denotes BMP
T10242 10530-10533 P22004 denotes BMP
T10243 10530-10533 P12643 denotes BMP
T10244 10530-10533 P12644 denotes BMP
T10245 10530-10535 P22004 denotes BMP-6
T10246 10606-10609 P18075 denotes BMP
T10247 10606-10609 P12644 denotes BMP
T10248 10606-10609 P12643 denotes BMP
T10249 10606-10609 P22004 denotes BMP
T10250 10606-10611 P22004 denotes BMP-6
T9826 66-69 P12643 denotes BMP
T9827 66-69 P12644 denotes BMP
T9828 66-69 P18075 denotes BMP
T9829 66-69 P22004 denotes BMP
T9830 192-196 P22004 denotes BMPs
T9831 192-196 P12644 denotes BMPs
T9832 192-196 P12643 denotes BMPs
T9833 192-196 P18075 denotes BMPs
T9834 328-331 P22004 denotes BMP
T9835 328-331 P18075 denotes BMP
T9836 328-331 P12643 denotes BMP
T9837 328-331 P12644 denotes BMP
T9838 328-333 P22004 denotes BMP-6
T9839 354-358 P15391 denotes CD19
T9840 383-386 P12643 denotes BMP
T9841 383-386 P12644 denotes BMP
T9842 383-386 P22004 denotes BMP
T9843 383-386 P18075 denotes BMP
T9844 383-388 P22004 denotes BMP-6
T9845 411-415 P26842 denotes CD27
T9846 497-500 P18075 denotes BMP
T9847 497-500 P22004 denotes BMP
T9848 497-500 P12644 denotes BMP
T9849 497-500 P12643 denotes BMP
T9850 497-502 P22004 denotes BMP-6
T9851 542-548 Q15797 denotes Smad-1
T9852 587-590 P12643 denotes BMP
T9853 587-590 P12644 denotes BMP
T9854 587-590 P18075 denotes BMP
T9855 587-590 P22004 denotes BMP
T9856 587-592 P22004 denotes BMP-6
T9857 666-669 P41134 denotes Id1
T9858 690-693 P41134 denotes Id1
T9859 770-773 P18075 denotes BMP

test2

Id Subject Object Predicate Lexical cue Negation Speculation
T7362 328-333 Protein denotes BMP-6
T7363 354-358 Protein denotes CD19
T7364 383-388 Protein denotes BMP-6
T7365 411-415 Protein denotes CD27
T7366 497-502 Protein denotes BMP-6
T7367 503-510 Positive_regulation denotes induced
T7368 530-538 Positive_regulation denotes increase
T7369 542-548 Protein denotes Smad-1
T7370 549-550 Protein denotes 5
T7371 551-552 Protein denotes 8
T7372 553-568 Phosphorylation denotes phosphorylation
T7373 587-592 Protein denotes BMP-6
T7374 593-600 Positive_regulation denotes induced
T7375 601-605 Protein denotes Smad
T7376 606-621 Phosphorylation denotes phosphorylation
T7377 626-634 Positive_regulation denotes followed
T7378 650-662 Positive_regulation denotes upregulation
T7379 666-669 Protein denotes Id1
T7380 690-693 Protein denotes Id1
T7381 770-775 Protein denotes BMP-6
T7382 886-891 Protein denotes BMP-6
T7383 912-923 Negative_regulation denotes neutralized
T7384 959-965 Protein denotes Noggin
T7385 1009-1015 Protein denotes Noggin
T7386 1034-1039 Protein denotes BMP-6
T7387 1100-1107 Protein denotes BMP-RIB
T7388 1115-1122 Protein denotes BMP-RII
T7389 1192-1197 Protein denotes BMP-6
T7390 1613-1618 Protein denotes BMP-6
T7391 1680-1685 Protein denotes BMP-2
T7392 1687-1688 Protein denotes 4 true
T7393 1690-1691 Protein denotes 6
T7394 1696-1698 Protein denotes -7
T7395 1862-1867 Protein denotes BMP-4
T7396 2058-2063 Protein denotes BMP-6
T7397 2207-2214 Gene_expression denotes express
T7398 2240-2247 Protein denotes Act-RIA
T7399 2252-2259 Protein denotes BMP-RIB
T7400 2287-2294 Protein denotes BMP-RII
T7401 2299-2307 Protein denotes Act-RIIb
T7402 2328-2335 Binding denotes binding
T7403 2363-2368 Protein denotes BMP-6
T7404 2397-2402 Protein denotes BMP-6
T7405 2641-2656 Phosphorylation denotes phosphorylation
T7406 2689-2694 Protein denotes BMP-2
T7407 2713-2719 Positive_regulation denotes induce
T7408 2720-2730 Positive_regulation denotes activation
T7409 2734-2739 Protein denotes STAT3
T7410 2771-2786 Phosphorylation denotes phosphorylation
T7411 2833-2838 Protein denotes BMP-2
T7412 2904-2919 Phosphorylation denotes phosphorylation
T7413 2928-2933 Protein denotes STAT3
T7414 2938-2943 Protein denotes Smad1
T7415 2944-2945 Protein denotes 5
T7416 2946-2947 Protein denotes 8 true
T7417 3145-3150 Protein denotes BMP-6 true
T7418 3151-3158 Positive_regulation denotes induced
T7419 3159-3166 Regulation denotes changes
T7420 3174-3189 Phosphorylation denotes phosphorylation
T7421 3200-3205 Protein denotes STAT3 true
T7422 3270-3285 Phosphorylation denotes phosphorylation true
T7423 3289-3294 Protein denotes Smad1 true true
T7424 3295-3296 Protein denotes 5
T7425 3297-3298 Protein denotes 8
T7426 3369-3376 Positive_regulation denotes induced
T7427 3377-3392 Phosphorylation denotes phosphorylation
T7428 3396-3401 Protein denotes Smad1
T7429 3402-3403 Protein denotes 5
T7430 3404-3405 Protein denotes 8 true
T7431 3613-3625 Positive_regulation denotes Upregulation true
T7432 3629-3632 Protein denotes Id1 true
T7433 3633-3636 Positive_regulation denotes via
T7434 3637-3642 Protein denotes Smad1
T7435 3643-3644 Protein denotes 5
T7436 3645-3646 Protein denotes 8 true
T7437 3647-3662 Phosphorylation denotes phosphorylation
T7438 3688-3693 Protein denotes BMP-6 true
T7439 3912-3924 Positive_regulation denotes upregulation
T7440 3929-3932 Protein denotes Id1
T7441 3936-3941 Protein denotes BMP-6
T7442 3979-3982 Protein denotes Id2
T7443 3983-3986 Protein denotes Id4
T7444 4069-4081 Positive_regulation denotes upregulation
T7445 4085-4088 Protein denotes Id1 true
T7446 4118-4121 Protein denotes Id2
T7447 4126-4129 Protein denotes Id3 true
T7448 4177-4180 Protein denotes Id1
T7449 4211-4220 Gene_expression denotes expressed
T7450 4298-4308 Gene_expression denotes expression
T7451 4419-4431 Positive_regulation denotes upregulation
T7452 4435-4438 Protein denotes Id1
T7453 4553-4558 Protein denotes TGF-β
T7454 4598-4605 Positive_regulation denotes induces
T7455 4611-4614 Protein denotes Id2
T7456 4619-4622 Protein denotes Id3
T7457 4623-4633 Gene_expression denotes expression
T7458 4651-4654 Protein denotes Id1
T7459 4735-4740 Protein denotes TGF-β
T7460 4782-4785 Protein denotes Id2
T7461 4790-4793 Protein denotes Id3
T7462 4838-4847 Gene_expression denotes expressed
T7463 4901-4904 Protein denotes Id2
T7464 4909-4912 Protein denotes Id3 true
T7465 4950-4959 Gene_expression denotes expressed true
T7466 4965-4968 Protein denotes Id1
T7467 4998-5003 Protein denotes BMP-6
T7468 5012-5018 Positive_regulation denotes induce true
T7469 5031-5038 Regulation denotes changes true
T7470 5054-5064 Gene_expression denotes expression
T7471 5068-5071 Protein denotes Id2
T7472 5076-5079 Protein denotes Id3
T7473 5258-5262 Protein denotes Pax5 true
T7474 5333-5337 Binding denotes bind
T7475 5399-5403 Protein denotes Pax5
T7476 5693-5698 Protein denotes BMP-6
T7477 5727-5739 Positive_regulation denotes upregulation
T7478 5743-5746 Protein denotes Id1 true
T7479 5900-5905 Protein denotes TGF-β true
T7480 6171-6174 Protein denotes Id1 true true
T7481 6342-6347 Protein denotes BMP-6
T7482 6493-6497 Positive_regulation denotes High
T7483 6498-6503 Protein denotes BMP-6
T7484 6504-6519 Transcription denotes mRNA expression
T7485 6627-6635 Regulation denotes targeted
T7486 6636-6646 Gene_expression denotes expression
T7487 6650-6653 Protein denotes Id1
T7488 6794-6799 Protein denotes BMP-6
T7489 6875-6883 Positive_regulation denotes elevated
T7490 6894-6897 Protein denotes Id1
T7491 6902-6905 Protein denotes Id3
T7492 7183-7187 Protein denotes Id-1
T7493 7237-7247 Negative_regulation denotes inhibition
T7494 7251-7255 Protein denotes Id-1
T7495 7261-7271 Gene_expression denotes expression
T7496 7291-7296 Protein denotes BMP-6
T7497 7358-7363 Protein denotes BMP-6
T7498 7364-7373 Gene_expression denotes producing
T7499 7514-7518 Positive_regulation denotes High
T7500 7519-7524 Protein denotes BMP-6
T7501 7525-7540 Transcription denotes mRNA expression
T7502 7616-7626 Gene_expression denotes production
T7503 7630-7635 Protein denotes BMP-6
T7504 7636-7647 Transcription denotes transcripts
T7505 7720-7729 Regulation denotes autocrine
T7506 7730-7735 Protein denotes BMP-6
T7507 7871-7880 Regulation denotes autocrine
T7508 7881-7886 Protein denotes BMP-6
T7509 7926-7936 Gene_expression denotes expression
T7510 7937-7942 Protein denotes BMP-6
T7511 8014-8026 Positive_regulation denotes upregulation
T7512 8041-8046 Protein denotes BMP-6
T7513 8166-8171 Protein denotes BMP-6
T7514 8237-8244 Binding denotes binding
T7515 8338-8345 Gene_expression denotes express
T7516 8346-8351 Protein denotes BMP-6
T7517 8466-8471 Protein denotes BMP-6
T7518 8547-8552 Protein denotes BMP-6
T7519 8553-8563 Gene_expression denotes production
T7520 8629-8639 Gene_expression denotes production
T7521 8643-8648 Protein denotes BMP-6
T7522 8830-8842 Positive_regulation denotes upregulation
T7523 8850-8855 Protein denotes BMP-6
T7524 8939-8944 Protein denotes TGF-β
T7525 9180-9185 Protein denotes BMP-6
T7526 9336-9341 Protein denotes TGF-β
T7527 9368-9374 Protein denotes TGF-β1
T7528 9379-9384 Protein denotes BMP-4
T7529 9509-9521 Positive_regulation denotes upregulation
T7530 9525-9530 Protein denotes BMP-6
T7531 9581-9586 Protein denotes BMP-6
T7532 9625-9628 Protein denotes CD4
T7533 9633-9636 Protein denotes CD8
T7534 9679-9682 Protein denotes CD3
T7535 9692-9696 Protein denotes CD28
T7536 9807-9812 Protein denotes BMP-6
T7537 9973-9978 Protein denotes BMP-6
T7538 9979-9989 Gene_expression denotes production
T7539 10128-10135 Gene_expression denotes express
T7540 10136-10141 Protein denotes BMP-6
T7541 10199-10206 Gene_expression denotes produce
T7542 10207-10212 Protein denotes BMP-6
T7543 10256-10261 Protein denotes BMP-6
T7544 10304-10309 Protein denotes BMP-6
T7545 10530-10535 Protein denotes BMP-6
T7546 10606-10611 Protein denotes BMP-6
T7547 10612-10622 Gene_expression denotes production
R5726 T7366 T7367 causeOf BMP-6,induced
R5727 T7368 T7367 themeOf increase,induced
R5728 T7369 T7372 themeOf Smad-1,phosphorylation
R5729 T7370 T7372 themeOf 5,phosphorylation
R5730 T7371 T7372 themeOf 8,phosphorylation
R5731 T7372 T7368 themeOf phosphorylation,increase
R5732 T7373 T7374 causeOf BMP-6,induced
R5733 T7375 T7376 themeOf Smad,phosphorylation
R5734 T7376 T7377 causeOf phosphorylation,followed
R5735 T7376 T7374 themeOf phosphorylation,induced
R5736 T7378 T7377 themeOf upregulation,followed
R5737 T7379 T7378 themeOf Id1,upregulation
R5738 T7380 T7378 themeOf Id1,upregulation
R5739 T7382 T7383 themeOf BMP-6,neutralized
R5740 T7398 T7397 themeOf Act-RIA,express
R5741 T7398 T7402 themeOf Act-RIA,binding
R5742 T7399 T7397 themeOf BMP-RIB,express
R5743 T7399 T7402 themeOf BMP-RIB,binding
R5744 T7400 T7402 themeOf BMP-RII,binding
R5745 T7400 T7397 themeOf BMP-RII,express
R5746 T7401 T7402 themeOf Act-RIIb,binding
R5747 T7401 T7397 themeOf Act-RIIb,express
R5748 T7403 T7402 themeOf BMP-6,binding
R5749 T7406 T7407 causeOf BMP-2,induce
R5750 T7408 T7407 themeOf activation,induce
R5751 T7409 T7408 themeOf STAT3,activation
R5752 T7413 T7412 themeOf STAT3,phosphorylation
R5753 T7414 T7412 themeOf Smad1,phosphorylation
R5754 T7415 T7412 themeOf 5,phosphorylation
R5755 T7416 T7412 themeOf 8,phosphorylation
R5756 T7417 T7419 causeOf BMP-6,changes
R5757 T7417 T7418 causeOf BMP-6,induced
R5758 T7419 T7418 themeOf changes,induced
R5759 T7420 T7419 themeOf phosphorylation,changes
R5760 T7421 T7420 themeOf STAT3,phosphorylation
R5761 T7423 T7422 themeOf Smad1,phosphorylation
R5762 T7424 T7422 themeOf 5,phosphorylation
R5763 T7425 T7422 themeOf 8,phosphorylation
R5764 T7427 T7426 themeOf phosphorylation,induced
R5765 T7428 T7427 themeOf Smad1,phosphorylation
R5766 T7429 T7427 themeOf 5,phosphorylation
R5767 T7430 T7427 themeOf 8,phosphorylation
R5769 T7432 T7431 themeOf Id1,Upregulation
R5770 T7434 T7437 themeOf Smad1,phosphorylation
R5796 T7483 T7484 themeOf BMP-6,mRNA expression
R5797 T7484 T7482 themeOf mRNA expression,High
R5798 T7486 T7485 themeOf expression,targeted
R5799 T7487 T7486 themeOf Id1,expression
R5800 T7488 T7489 causeOf BMP-6,elevated
R5801 T7494 T7495 themeOf Id-1,expression
R5802 T7495 T7493 themeOf expression,inhibition
R5803 T7497 T7498 themeOf BMP-6,producing
R5804 T7500 T7501 themeOf BMP-6,mRNA expression
R5805 T7501 T7499 themeOf mRNA expression,High
R5806 T7503 T7502 themeOf BMP-6,production
R5807 T7503 T7504 themeOf BMP-6,transcripts
R5808 T7506 T7505 causeOf BMP-6,autocrine
R5809 T7508 T7507 causeOf BMP-6,autocrine
R5810 T7510 T7509 themeOf BMP-6,expression
R5811 T7512 T7511 themeOf BMP-6,upregulation
R5812 T7513 T7514 themeOf BMP-6,binding
R5813 T7516 T7515 themeOf BMP-6,express
R5814 T7518 T7519 themeOf BMP-6,production
R5815 T7521 T7520 themeOf BMP-6,production
R5816 T7523 T7522 themeOf BMP-6,upregulation
R5817 T7530 T7529 themeOf BMP-6,upregulation
R5818 T7537 T7538 themeOf BMP-6,production
R5819 T7540 T7539 themeOf BMP-6,express
R5820 T7542 T7541 themeOf BMP-6,produce
R5821 T7546 T7547 themeOf BMP-6,production
R5768 T7431 T7433 themeOf Upregulation,via
R5771 T7435 T7437 themeOf 5,phosphorylation
R5772 T7436 T7437 themeOf 8,phosphorylation
R5773 T7437 T7431 causeOf phosphorylation,Upregulation
R5774 T7440 T7439 themeOf Id1,upregulation
R5775 T7441 T7439 causeOf BMP-6,upregulation
R5776 T7445 T7444 themeOf Id1,upregulation
R5777 T7448 T7449 themeOf Id1,expressed
R5778 T7448 T7450 themeOf Id1,expression
R5779 T7452 T7451 themeOf Id1,upregulation
R5780 T7455 T7457 themeOf Id2,expression
R5781 T7456 T7457 themeOf Id3,expression
R5782 T7457 T7454 themeOf expression,induces
R5783 T7458 T7454 themeOf Id1,induces
R5784 T7460 T7462 themeOf Id2,expressed
R5785 T7461 T7462 themeOf Id3,expressed
R5786 T7463 T7465 themeOf Id2,expressed
R5787 T7464 T7465 themeOf Id3,expressed
R5788 T7466 T7465 themeOf Id1,expressed
R5789 T7467 T7468 causeOf BMP-6,induce
R5790 T7467 T7469 causeOf BMP-6,changes
R5791 T7470 T7469 themeOf expression,changes
R5792 T7471 T7470 themeOf Id2,expression
R5793 T7472 T7470 themeOf Id3,expression
R5794 T7473 T7474 themeOf Pax5,bind
R5795 T7478 T7477 themeOf Id1,upregulation

tees-test

Id Subject Object Predicate Lexical cue
T1360 66-69 CHEBI:60815 denotes BMP
T1361 66-69 PR:000000034 denotes BMP
T1362 66-69 P35855 denotes BMP
T1363 146-152 CL:0000236 denotes B-cell
T1364 153-165 D009369 denotes malignancies
T1365 153-165 D009369 denotes malignancies
T1366 207-212 D006801 denotes human
T1367 328-333 D055418 denotes BMP-6
T1368 328-333 D055418 denotes BMP-6
T1369 328-333 Q04906 denotes BMP-6
T1370 328-333 PR:000000167 denotes BMP-6
T1371 328-333 P20722 denotes BMP-6
T1372 328-333 PR:Q04906 denotes BMP-6
T1373 328-333 P22004 denotes BMP-6
T1374 328-333 PR:P22004 denotes BMP-6
T1375 328-333 PR:P20722 denotes BMP-6
T1376 354-358 PR:P25918 denotes CD19
T1377 354-358 PR:P15391 denotes CD19
T1378 354-358 PR:000001002 denotes CD19
T1379 383-388 D055418 denotes BMP-6
T1380 383-388 D055418 denotes BMP-6
T1381 383-388 Q04906 denotes BMP-6
T1382 383-388 PR:000000167 denotes BMP-6
T1383 383-388 P20722 denotes BMP-6
T1384 383-388 PR:Q04906 denotes BMP-6
T1385 383-388 P22004 denotes BMP-6
T1386 383-388 PR:P22004 denotes BMP-6
T1387 383-388 PR:P20722 denotes BMP-6
T1388 397-407 GO:0008219 denotes cell death
T1389 411-415 PR:P41272 denotes CD27
T1390 411-415 PR:000001963 denotes CD27
T1391 411-415 PR:P26842 denotes CD27
T1392 417-423 GO:0007613 denotes memory
T1393 448-464 D002051 denotes Burkitt lymphoma
T1394 448-464 D002051 denotes Burkitt lymphoma
T1395 476-481 CVCL_0597 denotes Ramos
T1396 497-502 D055418 denotes BMP-6
T1397 497-502 D055418 denotes BMP-6
T1398 497-502 Q04906 denotes BMP-6
T1399 497-502 PR:000000167 denotes BMP-6
T1400 497-502 P20722 denotes BMP-6
T1401 497-502 PR:Q04906 denotes BMP-6
T1402 497-502 P22004 denotes BMP-6
T1403 497-502 PR:P22004 denotes BMP-6
T1404 497-502 PR:P20722 denotes BMP-6
T1405 542-548 PR:Q9I8V2 denotes Smad-1
T1406 542-548 PR:P97588 denotes Smad-1
T1407 542-548 Q15797 denotes Smad-1
T1408 542-548 PR:000000363 denotes Smad-1
T1409 542-548 PR:P70340 denotes Smad-1
T1410 542-548 P70340 denotes Smad-1
T1411 542-548 Q9I962 denotes Smad-1
T1412 542-548 PR:Q15797 denotes Smad-1
T1413 542-548 P97588 denotes Smad-1
T1414 542-548 Q9I8V2 denotes Smad-1
T1415 542-548 Q1JQA2 denotes Smad-1
T1416 553-568 GO:0016310 denotes phosphorylation
T1417 587-592 D055418 denotes BMP-6
T1418 587-592 D055418 denotes BMP-6
T1419 587-592 Q04906 denotes BMP-6
T1420 587-592 PR:000000167 denotes BMP-6
T1421 587-592 P20722 denotes BMP-6
T1422 587-592 PR:Q04906 denotes BMP-6
T1423 587-592 P22004 denotes BMP-6
T1424 587-592 PR:P22004 denotes BMP-6
T1425 587-592 PR:P20722 denotes BMP-6
T1426 606-621 GO:0016310 denotes phosphorylation
T1427 666-669 PR:P41134 denotes Id1
T1428 666-669 PR:P20067 denotes Id1
T1429 666-669 PR:P41135 denotes Id1
T1430 666-669 PR:000000039 denotes Id1
T1431 670-674 D012333 denotes mRNA
T1432 670-674 CHEBI:33699 denotes mRNA
T1433 670-674 SO:0000234 denotes mRNA
T1434 690-693 PR:P41134 denotes Id1
T1435 690-693 PR:P20067 denotes Id1
T1436 690-693 PR:P41135 denotes Id1
T1437 690-693 PR:000000039 denotes Id1
T1438 694-701 CHEBI:36080 denotes protein
T1439 694-701 CHEBI:11122 denotes protein
T1440 694-701 PR:000000001 denotes protein
T1441 694-701 SO:0000104 denotes protein
T1442 694-701 GO:0003675 denotes protein
T1443 770-775 D055418 denotes BMP-6
T1444 770-775 D055418 denotes BMP-6
T1445 770-775 Q04906 denotes BMP-6
T1446 770-775 PR:000000167 denotes BMP-6
T1447 770-775 P20722 denotes BMP-6
T1448 770-775 PR:Q04906 denotes BMP-6
T1449 770-775 P22004 denotes BMP-6
T1450 770-775 PR:P22004 denotes BMP-6
T1451 770-775 PR:P20722 denotes BMP-6
T1452 779-787 C044203 denotes anti-IgM
T1453 886-891 D055418 denotes BMP-6
T1454 886-891 D055418 denotes BMP-6
T1455 886-891 Q04906 denotes BMP-6
T1456 886-891 PR:000000167 denotes BMP-6
T1457 886-891 P20722 denotes BMP-6
T1458 886-891 PR:Q04906 denotes BMP-6
T1459 886-891 P22004 denotes BMP-6
T1460 886-891 PR:P22004 denotes BMP-6
T1461 886-891 PR:P20722 denotes BMP-6
T1462 948-957 CHEBI:35222 denotes inhibitor
T1463 959-965 P97466 denotes Noggin
T1464 959-965 Q13253 denotes Noggin
T1465 959-965 Q9YHT8 denotes Noggin
T1466 959-965 PR:000000021 denotes Noggin
T1467 959-965 O93525 denotes Noggin
T1468 959-965 P49011 denotes Noggin
T1469 959-965 Q62809 denotes Noggin
T1470 1009-1015 P97466 denotes Noggin
T1471 1009-1015 Q13253 denotes Noggin
T1472 1009-1015 Q9YHT8 denotes Noggin
T1473 1009-1015 PR:000000021 denotes Noggin
T1474 1009-1015 O93525 denotes Noggin
T1475 1009-1015 P49011 denotes Noggin
T1476 1009-1015 Q62809 denotes Noggin
T1477 1034-1039 Q04906 denotes BMP-6
T1478 1034-1039 PR:000000167 denotes BMP-6
T1479 1034-1039 P20722 denotes BMP-6
T1480 1034-1039 PR:Q04906 denotes BMP-6
T1481 1034-1039 P22004 denotes BMP-6
T1482 1034-1039 PR:P22004 denotes BMP-6
T1483 1034-1039 PR:P20722 denotes BMP-6
T1484 1034-1039 D055418 denotes BMP-6
T1485 1034-1039 D055418 denotes BMP-6
T1486 1040-1050 CHEBI:48706 denotes antagonist
T1487 1092-1099 GO:0005625 denotes soluble
T1488 1100-1103 CHEBI:60815 denotes BMP
T1489 1100-1103 PR:000000034 denotes BMP
T1490 1100-1103 P35855 denotes BMP
T1491 1104-1107 CHEBI:33942 denotes RIB
T1492 1104-1107 UBERON:0002228 denotes RIB
T1493 1115-1118 CHEBI:60815 denotes BMP
T1494 1115-1118 PR:000000034 denotes BMP
T1495 1115-1118 P35855 denotes BMP
T1496 1126-1132 SO:0000806 denotes fusion
T1497 1133-1141 CHEBI:36080 denotes proteins
T1498 1192-1197 D055418 denotes BMP-6
T1499 1192-1197 D055418 denotes BMP-6
T1500 1192-1197 Q04906 denotes BMP-6
T1501 1192-1197 PR:000000167 denotes BMP-6
T1502 1192-1197 P20722 denotes BMP-6
T1503 1192-1197 PR:Q04906 denotes BMP-6
T1504 1192-1197 P22004 denotes BMP-6
T1505 1192-1197 PR:P22004 denotes BMP-6
T1506 1192-1197 PR:P20722 denotes BMP-6
T1507 1201-1206 D006801 denotes human
T1508 1378-1391 UBERON:2000098 denotes proliferation
T1509 1442-1447 UBERON:0002107 denotes liver
T1510 1509-1531 GO:0006915 denotes induction of apoptosis
T1511 1613-1618 D055418 denotes BMP-6
T1512 1613-1618 D055418 denotes BMP-6
T1513 1613-1618 Q04906 denotes BMP-6
T1514 1613-1618 PR:000000167 denotes BMP-6
T1515 1613-1618 P20722 denotes BMP-6
T1516 1613-1618 PR:Q04906 denotes BMP-6
T1517 1613-1618 P22004 denotes BMP-6
T1518 1613-1618 PR:P22004 denotes BMP-6
T1519 1613-1618 PR:P20722 denotes BMP-6
T1520 1619-1627 PR:P09486 denotes on human
T1521 1622-1627 D006801 denotes human
T1522 1680-1683 CHEBI:60815 denotes BMP
T1523 1680-1685 PR:P49001 denotes BMP-2
T1524 1680-1685 PR:P21274 denotes BMP-2
T1525 1680-1685 Q804S2 denotes BMP-2
T1526 1680-1685 P49001 denotes BMP-2
T1527 1680-1685 P12643 denotes BMP-2
T1528 1680-1685 P21274 denotes BMP-2
T1529 1680-1685 Q90751 denotes BMP-2
T1530 1680-1685 O46564 denotes BMP-2
T1531 1680-1685 PR:P12643 denotes BMP-2
T1532 1680-1685 PR:000000164 denotes BMP-2
T1533 1680-1685 O19006 denotes BMP-2
T1534 1702-1707 D006801 denotes human
T1535 1751-1754 CHEBI:60815 denotes BMP
T1536 1751-1754 PR:000000034 denotes BMP
T1537 1751-1754 P35855 denotes BMP
T1538 1796-1805 GO:0097194 denotes apoptosis
T1539 1796-1805 GO:0006915 denotes apoptosis
T1540 1820-1825 10090 denotes mouse
T1541 1820-1825 D051379 denotes mouse
T1542 1862-1865 CHEBI:60815 denotes BMP
T1543 1862-1867 O46576 denotes BMP-4
T1544 1862-1867 Q8MJV5 denotes BMP-4
T1545 1862-1867 PR:Q06826 denotes BMP-4
T1546 1862-1867 P12644 denotes BMP-4
T1547 1862-1867 PR:P12644 denotes BMP-4
T1548 1862-1867 P30885 denotes BMP-4
T1549 1862-1867 PR:000000165 denotes BMP-4
T1550 1862-1867 Q90752 denotes BMP-4
T1551 1862-1867 Q06826 denotes BMP-4
T1552 1862-1867 PR:P21275 denotes BMP-4
T1553 1862-1867 Q29607 denotes BMP-4
T1554 1862-1867 Q2KJH1 denotes BMP-4
T1555 1862-1867 P21275 denotes BMP-4
T1556 1877-1886 CL:0000893 denotes thymocyte
T1557 1877-1900 GO:0033080 denotes thymocyte proliferation
T1558 1887-1900 UBERON:2000098 denotes proliferation
T1559 1970-1980 GO:0065007 denotes regulation
T1560 1984-1997 UBERON:2000098 denotes proliferation
T1561 2002-2011 GO:0097194 denotes apoptosis
T1562 2002-2011 GO:0006915 denotes apoptosis
T1563 2058-2063 D055418 denotes BMP-6
T1564 2058-2063 D055418 denotes BMP-6
T1565 2058-2063 Q04906 denotes BMP-6
T1566 2058-2063 PR:000000167 denotes BMP-6
T1567 2058-2063 P20722 denotes BMP-6
T1568 2058-2063 PR:Q04906 denotes BMP-6
T1569 2058-2063 P22004 denotes BMP-6
T1570 2058-2063 PR:P22004 denotes BMP-6
T1571 2058-2063 PR:P20722 denotes BMP-6
T1572 2118-2121 PR:000000034 denotes BMP
T1573 2118-2121 P35855 denotes BMP
T1574 2118-2130 D052004 denotes BMP receptor
T1575 2168-2173 D006801 denotes Human
T1576 2219-2222 CHEBI:60815 denotes BMP
T1577 2219-2222 PR:000000034 denotes BMP
T1578 2219-2222 P35855 denotes BMP
T1579 2252-2255 CHEBI:60815 denotes BMP
T1580 2252-2255 PR:000000034 denotes BMP
T1581 2252-2255 P35855 denotes BMP
T1582 2256-2259 CHEBI:33942 denotes RIB
T1583 2256-2259 UBERON:0002228 denotes RIB
T1584 2277-2290 D052004 denotes receptors BMP
T1585 2287-2290 PR:000000034 denotes BMP
T1586 2287-2290 P35855 denotes BMP
T1587 2315-2321 SO:0000725 denotes signal
T1588 2315-2321 SO:0000418 denotes signal
T1589 2328-2335 SO:0100018 denotes binding
T1590 2328-2335 SO:0001091 denotes binding
T1591 2328-2335 GO:0005488 denotes binding
T1592 2363-2368 D055418 denotes BMP-6
T1593 2363-2368 D055418 denotes BMP-6
T1594 2363-2368 Q04906 denotes BMP-6
T1595 2363-2368 PR:000000167 denotes BMP-6
T1596 2363-2368 P20722 denotes BMP-6
T1597 2363-2368 PR:Q04906 denotes BMP-6
T1598 2363-2368 P22004 denotes BMP-6
T1599 2363-2368 PR:P22004 denotes BMP-6
T1600 2363-2368 PR:P20722 denotes BMP-6
T1601 2397-2402 D055418 denotes BMP-6
T1602 2397-2402 D055418 denotes BMP-6
T1603 2397-2402 Q04906 denotes BMP-6
T1604 2397-2402 PR:000000167 denotes BMP-6
T1605 2397-2402 P20722 denotes BMP-6
T1606 2397-2402 PR:Q04906 denotes BMP-6
T1607 2397-2402 P22004 denotes BMP-6
T1608 2397-2402 PR:P22004 denotes BMP-6
T1609 2397-2402 PR:P20722 denotes BMP-6
T1610 2411-2421 GO:0023052 denotes signalling
T1611 2477-2495 GO:0007165 denotes signalling pathway
T1612 2488-2495 CHEBI:34922 denotes pathway
T1613 2641-2656 GO:0016310 denotes phosphorylation
T1614 2689-2692 CHEBI:60815 denotes BMP
T1615 2689-2694 PR:P49001 denotes BMP-2
T1616 2689-2694 PR:P21274 denotes BMP-2
T1617 2689-2694 Q804S2 denotes BMP-2
T1618 2689-2694 P49001 denotes BMP-2
T1619 2689-2694 P12643 denotes BMP-2
T1620 2689-2694 P21274 denotes BMP-2
T1621 2689-2694 Q90751 denotes BMP-2
T1622 2689-2694 O46564 denotes BMP-2
T1623 2689-2694 PR:P12643 denotes BMP-2
T1624 2689-2694 PR:000000164 denotes BMP-2
T1625 2689-2694 O19006 denotes BMP-2
T1626 2734-2739 PR:000002089 denotes STAT3
T1627 2734-2739 PR:P42227 denotes STAT3
T1628 2734-2739 PR:Q6DV79 denotes STAT3
T1629 2734-2739 PR:P40763 denotes STAT3
T1630 2734-2739 PR:P52631 denotes STAT3
T1631 2771-2786 GO:0016310 denotes phosphorylation
T1632 2833-2836 CHEBI:60815 denotes BMP
T1633 2833-2838 PR:P49001 denotes BMP-2
T1634 2833-2838 PR:P21274 denotes BMP-2
T1635 2833-2838 Q804S2 denotes BMP-2
T1636 2833-2838 P49001 denotes BMP-2
T1637 2833-2838 P12643 denotes BMP-2
T1638 2833-2838 P21274 denotes BMP-2
T1639 2833-2838 Q90751 denotes BMP-2
T1640 2833-2838 O46564 denotes BMP-2
T1641 2833-2838 PR:P12643 denotes BMP-2
T1642 2833-2838 PR:000000164 denotes BMP-2
T1643 2833-2838 O19006 denotes BMP-2
T1644 2869-2884 GO:0016310 denotes phosphorylation
T1645 2888-2891 PR:000005882 denotes p38
T1646 2888-2891 O24473 denotes p38
T1647 2888-2891 P46108 denotes p38
T1648 2888-2891 Q64010 denotes p38
T1649 2888-2891 A0A0H3M950 denotes p38
T1650 2888-2891 P0C797 denotes p38
T1651 2888-2891 P04383 denotes p38
T1652 2888-2891 O95433 denotes p38
T1653 2888-2891 Q63768 denotes p38
T1654 2888-2891 PR:Q9LDA4 denotes p38
T1655 2888-2891 P06663 denotes p38
T1656 2888-2891 P0C796 denotes p38
T1657 2888-2891 PR:000003860 denotes p38
T1658 2888-2891 Q9NV58 denotes p38
T1659 2888-2891 O75791 denotes p38
T1660 2888-2891 PR:000008220 denotes p38
T1661 2888-2891 A0A0H3MBK5 denotes p38
T1662 2888-2891 P80350 denotes p38
T1663 2888-2891 PR:000012967 denotes p38
T1664 2888-2891 O97628 denotes p38
T1665 2888-2891 A0A0H3MBL5 denotes p38
T1666 2888-2891 Q9Y2S7 denotes p38
T1667 2888-2891 PR:000014113 denotes p38
T1668 2888-2891 P82869 denotes p38
T1669 2888-2891 Q9Q6X7 denotes p38
T1670 2888-2891 P9WGU1 denotes p38
T1671 2888-2891 Q04929 denotes p38
T1672 2904-2919 GO:0016310 denotes phosphorylation
T1673 2923-2926 PR:000005882 denotes p38
T1674 2923-2926 O24473 denotes p38
T1675 2923-2926 P46108 denotes p38
T1676 2923-2926 Q64010 denotes p38
T1677 2923-2926 A0A0H3M950 denotes p38
T1678 2923-2926 P0C797 denotes p38
T1679 2923-2926 P04383 denotes p38
T1680 2923-2926 O95433 denotes p38
T1681 2923-2926 Q63768 denotes p38
T1682 2923-2926 PR:Q9LDA4 denotes p38
T1683 2923-2926 P06663 denotes p38
T1684 2923-2926 P0C796 denotes p38
T1685 2923-2926 PR:000003860 denotes p38
T1686 2923-2926 Q9NV58 denotes p38
T1687 2923-2926 O75791 denotes p38
T1688 2923-2926 PR:000008220 denotes p38
T1689 2923-2926 A0A0H3MBK5 denotes p38
T1690 2923-2926 P80350 denotes p38
T1691 2923-2926 PR:000012967 denotes p38
T1692 2923-2926 O97628 denotes p38
T1693 2923-2926 A0A0H3MBL5 denotes p38
T1694 2923-2926 Q9Y2S7 denotes p38
T1695 2923-2926 PR:000014113 denotes p38
T1696 2923-2926 P82869 denotes p38
T1697 2923-2926 Q9Q6X7 denotes p38
T1698 2923-2926 P9WGU1 denotes p38
T1699 2923-2926 Q04929 denotes p38
T1700 2928-2933 PR:000002089 denotes STAT3
T1701 2928-2933 PR:P42227 denotes STAT3
T1702 2928-2933 PR:Q6DV79 denotes STAT3
T1703 2928-2933 PR:P40763 denotes STAT3
T1704 2928-2933 PR:P52631 denotes STAT3
T1705 2938-2943 PR:Q9I8V2 denotes Smad1
T1706 2938-2943 PR:P97588 denotes Smad1
T1707 2938-2943 Q15797 denotes Smad1
T1708 2938-2943 PR:000000363 denotes Smad1
T1709 2938-2943 PR:P70340 denotes Smad1
T1710 2938-2943 P70340 denotes Smad1
T1711 2938-2943 Q9I962 denotes Smad1
T1712 2938-2943 PR:Q15797 denotes Smad1
T1713 2938-2943 P97588 denotes Smad1
T1714 2938-2943 Q9I8V2 denotes Smad1
T1715 2938-2943 Q1JQA2 denotes Smad1
T1716 2968-2971 PR:000000034 denotes BMP
T1717 2968-2971 P35855 denotes BMP
T1718 2968-2971 CHEBI:60815 denotes BMP
T1719 2972-2982 GO:0023052 denotes signalling
T1720 3145-3150 D055418 denotes BMP-6
T1721 3145-3150 D055418 denotes BMP-6
T1722 3145-3150 Q04906 denotes BMP-6
T1723 3145-3150 PR:000000167 denotes BMP-6
T1724 3145-3150 P20722 denotes BMP-6
T1725 3145-3150 PR:Q04906 denotes BMP-6
T1726 3145-3150 P22004 denotes BMP-6
T1727 3145-3150 PR:P22004 denotes BMP-6
T1728 3145-3150 PR:P20722 denotes BMP-6
T1729 3174-3189 GO:0016310 denotes phosphorylation
T1730 3200-3205 PR:000002089 denotes STAT3
T1731 3200-3205 PR:P42227 denotes STAT3
T1732 3200-3205 PR:Q6DV79 denotes STAT3
T1733 3200-3205 PR:P40763 denotes STAT3
T1734 3200-3205 PR:P52631 denotes STAT3
T1735 3209-3212 PR:000005882 denotes p38
T1736 3209-3212 O24473 denotes p38
T1737 3209-3212 P46108 denotes p38
T1738 3209-3212 Q64010 denotes p38
T1739 3209-3212 A0A0H3M950 denotes p38
T1740 3209-3212 P0C797 denotes p38
T1741 3209-3212 P04383 denotes p38
T1742 3209-3212 O95433 denotes p38
T1743 3209-3212 Q63768 denotes p38
T1744 3209-3212 PR:Q9LDA4 denotes p38
T1745 3209-3212 P06663 denotes p38
T1746 3209-3212 P0C796 denotes p38
T1747 3209-3212 PR:000003860 denotes p38
T1748 3209-3212 Q9NV58 denotes p38
T1749 3209-3212 O75791 denotes p38
T1750 3209-3212 PR:000008220 denotes p38
T1751 3209-3212 A0A0H3MBK5 denotes p38
T1752 3209-3212 P80350 denotes p38
T1753 3209-3212 PR:000012967 denotes p38
T1754 3209-3212 O97628 denotes p38
T1755 3209-3212 A0A0H3MBL5 denotes p38
T1756 3209-3212 Q9Y2S7 denotes p38
T1757 3209-3212 PR:000014113 denotes p38
T1758 3209-3212 P82869 denotes p38
T1759 3209-3212 Q9Q6X7 denotes p38
T1760 3209-3212 P9WGU1 denotes p38
T1761 3209-3212 Q04929 denotes p38
T1762 3216-3221 D006801 denotes human
T1763 3270-3285 GO:0016310 denotes phosphorylation
T1764 3289-3294 PR:Q9I8V2 denotes Smad1
T1765 3289-3294 PR:P97588 denotes Smad1
T1766 3289-3294 Q15797 denotes Smad1
T1767 3289-3294 PR:000000363 denotes Smad1
T1768 3289-3294 PR:P70340 denotes Smad1
T1769 3289-3294 P70340 denotes Smad1
T1770 3289-3294 Q9I962 denotes Smad1
T1771 3289-3294 PR:Q15797 denotes Smad1
T1772 3289-3294 P97588 denotes Smad1
T1773 3289-3294 Q9I8V2 denotes Smad1
T1774 3289-3294 Q1JQA2 denotes Smad1
T1775 3377-3392 GO:0016310 denotes phosphorylation
T1776 3396-3401 PR:Q9I8V2 denotes Smad1
T1777 3396-3401 PR:P97588 denotes Smad1
T1778 3396-3401 Q15797 denotes Smad1
T1779 3396-3401 PR:000000363 denotes Smad1
T1780 3396-3401 PR:P70340 denotes Smad1
T1781 3396-3401 P70340 denotes Smad1
T1782 3396-3401 Q9I962 denotes Smad1
T1783 3396-3401 PR:Q15797 denotes Smad1
T1784 3396-3401 P97588 denotes Smad1
T1785 3396-3401 Q9I8V2 denotes Smad1
T1786 3396-3401 Q1JQA2 denotes Smad1
T1787 3434-3443 32644 denotes not shown
T1788 3507-3517 GO:0023052 denotes signalling
T1789 3565-3574 SO:0000119 denotes regulated
T1790 3598-3603 D006801 denotes human
T1791 3629-3632 PR:P41134 denotes Id1
T1792 3629-3632 PR:P20067 denotes Id1
T1793 3629-3632 PR:P41135 denotes Id1
T1794 3629-3632 PR:000000039 denotes Id1
T1795 3637-3642 PR:Q9I8V2 denotes Smad1
T1796 3637-3642 PR:P97588 denotes Smad1
T1797 3637-3642 Q15797 denotes Smad1
T1798 3637-3642 PR:000000363 denotes Smad1
T1799 3637-3642 PR:P70340 denotes Smad1
T1800 3637-3642 P70340 denotes Smad1
T1801 3637-3642 Q9I962 denotes Smad1
T1802 3637-3642 PR:Q15797 denotes Smad1
T1803 3637-3642 P97588 denotes Smad1
T1804 3637-3642 Q9I8V2 denotes Smad1
T1805 3637-3642 Q1JQA2 denotes Smad1
T1806 3647-3662 GO:0016310 denotes phosphorylation
T1807 3688-3693 Q04906 denotes BMP-6
T1808 3688-3693 PR:000000167 denotes BMP-6
T1809 3688-3693 P20722 denotes BMP-6
T1810 3688-3693 PR:Q04906 denotes BMP-6
T1811 3688-3693 P22004 denotes BMP-6
T1812 3688-3693 PR:P22004 denotes BMP-6
T1813 3688-3693 PR:P20722 denotes BMP-6
T1814 3688-3693 D055418 denotes BMP-6
T1815 3688-3693 D055418 denotes BMP-6
T1816 3694-3704 GO:0023052 denotes signalling
T1817 3739-3749 GO:0065007 denotes regulation
T1818 3756-3764 CHEBI:36080 denotes proteins
T1819 3814-3824 GO:0023052 denotes signalling
T1820 3866-3869 Q41249 denotes PCR
T1821 3866-3869 O66148 denotes PCR
T1822 3866-3869 Q59987 denotes PCR
T1823 3866-3869 Q01289 denotes PCR
T1824 3866-3869 O80333 denotes PCR
T1825 3866-3869 P15904 denotes PCR
T1826 3866-3869 Q9SDT1 denotes PCR
T1827 3866-3869 Q39617 denotes PCR
T1828 3907-3911 PR:000022679 denotes fold
T1829 3907-3911 PR:Q2FZJ6 denotes fold
T1830 3907-3911 PR:A5I112 denotes fold
T1831 3907-3911 PR:P24186 denotes fold
T1832 3929-3932 PR:P41134 denotes Id1
T1833 3929-3932 PR:P20067 denotes Id1
T1834 3929-3932 PR:P41135 denotes Id1
T1835 3929-3932 PR:000000039 denotes Id1
T1836 3936-3941 Q04906 denotes BMP-6
T1837 3936-3941 PR:000000167 denotes BMP-6
T1838 3936-3941 P20722 denotes BMP-6
T1839 3936-3941 PR:Q04906 denotes BMP-6
T1840 3936-3941 P22004 denotes BMP-6
T1841 3936-3941 PR:P22004 denotes BMP-6
T1842 3936-3941 PR:P20722 denotes BMP-6
T1843 3936-3941 D055418 denotes BMP-6
T1844 3936-3941 D055418 denotes BMP-6
T1845 3979-3982 PR:000000040 denotes Id2
T1846 3979-3982 PR:P41137 denotes Id2
T1847 3979-3982 PR:Q02363 denotes Id2
T1848 3979-3982 PR:P41136 denotes Id2
T1849 3979-3982 C039556 denotes Id2
T1850 3979-3982 C039556 denotes Id2
T1851 3983-3986 PR:P47928 denotes Id4
T1852 3983-3986 PR:P41139 denotes Id4
T1853 3983-3986 PR:000000042 denotes Id4
T1854 4085-4088 PR:P41134 denotes Id1
T1855 4085-4088 PR:P20067 denotes Id1
T1856 4085-4088 PR:P41135 denotes Id1
T1857 4085-4088 PR:000000039 denotes Id1
T1858 4089-4096 PR:000000001 denotes protein
T1859 4089-4096 GO:0003675 denotes protein
T1860 4089-4096 CHEBI:36080 denotes protein
T1861 4089-4096 CHEBI:11122 denotes protein
T1862 4089-4096 SO:0000104 denotes protein
T1863 4118-4121 PR:000000040 denotes Id2
T1864 4118-4121 PR:P41137 denotes Id2
T1865 4118-4121 PR:Q02363 denotes Id2
T1866 4118-4121 PR:P41136 denotes Id2
T1867 4118-4121 C039556 denotes Id2
T1868 4118-4121 C039556 denotes Id2
T1869 4126-4129 PR:P41133 denotes Id3
T1870 4126-4129 PR:P41138 denotes Id3
T1871 4126-4129 PR:Q02535 denotes Id3
T1872 4126-4129 PR:000000041 denotes Id3
T1873 4130-4137 PR:000000001 denotes protein
T1874 4130-4137 GO:0003675 denotes protein
T1875 4130-4137 CHEBI:36080 denotes protein
T1876 4130-4137 CHEBI:11122 denotes protein
T1877 4130-4137 SO:0000104 denotes protein
T1878 4177-4180 PR:P41134 denotes Id1
T1879 4177-4180 PR:P20067 denotes Id1
T1880 4177-4180 PR:P41135 denotes Id1
T1881 4177-4180 PR:000000039 denotes Id1
T1882 4256-4259 CVCL_N817 denotes pro
T1883 4256-4259 CHEBI:32871 denotes pro
T1884 4256-4259 CHEBI:32865 denotes pro
T1885 4256-4259 CHEBI:50342 denotes pro
T1886 4256-4259 CHEBI:32866 denotes pro
T1887 4256-4259 SO:0001439 denotes pro
T1888 4337-4342 10090 denotes mouse
T1889 4337-4342 D051379 denotes mouse
T1890 4343-4349 CL:0000236 denotes B cell
T1891 4343-4361 GO:0030183 denotes B cell development
T1892 4435-4438 PR:P41134 denotes Id1
T1893 4435-4438 PR:P20067 denotes Id1
T1894 4435-4438 PR:P41135 denotes Id1
T1895 4435-4438 PR:000000039 denotes Id1
T1896 4439-4443 D012333 denotes mRNA
T1897 4439-4443 CHEBI:33699 denotes mRNA
T1898 4439-4443 SO:0000234 denotes mRNA
T1899 4448-4455 PR:000000001 denotes protein
T1900 4448-4455 CHEBI:36080 denotes protein
T1901 4448-4455 CHEBI:11122 denotes protein
T1902 4448-4455 SO:0000104 denotes protein
T1903 4448-4455 GO:0003675 denotes protein
T1904 4473-4478 D006801 denotes human
T1905 4553-4558 PR:000000046 denotes TGF-β
T1906 4553-4558 D016212 denotes TGF-β
T1907 4553-4558 D016212 denotes TGF-β
T1908 4559-4569 GO:0023052 denotes signalling
T1909 4611-4614 PR:000000040 denotes Id2
T1910 4611-4614 PR:P41137 denotes Id2
T1911 4611-4614 PR:Q02363 denotes Id2
T1912 4611-4614 PR:P41136 denotes Id2
T1913 4611-4614 C039556 denotes Id2
T1914 4611-4614 C039556 denotes Id2
T1915 4619-4622 PR:P41133 denotes Id3
T1916 4619-4622 PR:P41138 denotes Id3
T1917 4619-4622 PR:Q02535 denotes Id3
T1918 4619-4622 PR:000000041 denotes Id3
T1919 4651-4654 PR:P41134 denotes Id1
T1920 4651-4654 PR:P20067 denotes Id1
T1921 4651-4654 PR:P41135 denotes Id1
T1922 4651-4654 PR:000000039 denotes Id1
T1923 4661-4670 32644 denotes not shown
T1924 4735-4740 PR:000000046 denotes TGF-β
T1925 4735-4740 D016212 denotes TGF-β
T1926 4735-4740 D016212 denotes TGF-β
T1927 4760-4768 CHEBI:36080 denotes proteins
T1928 4782-4785 PR:000000040 denotes Id2
T1929 4782-4785 PR:P41137 denotes Id2
T1930 4782-4785 PR:Q02363 denotes Id2
T1931 4782-4785 PR:P41136 denotes Id2
T1932 4782-4785 C039556 denotes Id2
T1933 4782-4785 C039556 denotes Id2
T1934 4790-4793 PR:P41133 denotes Id3
T1935 4790-4793 PR:P41138 denotes Id3
T1936 4790-4793 PR:Q02535 denotes Id3
T1937 4790-4793 PR:000000041 denotes Id3
T1938 4822-4830 CHEBI:36080 denotes proteins
T1939 4901-4904 PR:000000040 denotes Id2
T1940 4901-4904 PR:P41137 denotes Id2
T1941 4901-4904 PR:Q02363 denotes Id2
T1942 4901-4904 PR:P41136 denotes Id2
T1943 4901-4904 C039556 denotes Id2
T1944 4901-4904 C039556 denotes Id2
T1945 4909-4912 PR:P41133 denotes Id3
T1946 4909-4912 PR:P41138 denotes Id3
T1947 4909-4912 PR:Q02535 denotes Id3
T1948 4909-4912 PR:000000041 denotes Id3
T1949 4913-4920 PR:000000001 denotes protein
T1950 4913-4920 CHEBI:36080 denotes protein
T1951 4913-4920 CHEBI:11122 denotes protein
T1952 4913-4920 GO:0003675 denotes protein
T1953 4913-4920 SO:0000104 denotes protein
T1954 4965-4968 PR:P41134 denotes Id1
T1955 4965-4968 PR:P20067 denotes Id1
T1956 4965-4968 PR:P41135 denotes Id1
T1957 4965-4968 PR:000000039 denotes Id1
T1958 4998-5003 D055418 denotes BMP-6
T1959 4998-5003 D055418 denotes BMP-6
T1960 4998-5003 Q04906 denotes BMP-6
T1961 4998-5003 PR:000000167 denotes BMP-6
T1962 4998-5003 P20722 denotes BMP-6
T1963 4998-5003 PR:Q04906 denotes BMP-6
T1964 4998-5003 P22004 denotes BMP-6
T1965 4998-5003 PR:P22004 denotes BMP-6
T1966 4998-5003 PR:P20722 denotes BMP-6
T1967 5046-5053 CHEBI:36080 denotes protein
T1968 5046-5053 CHEBI:11122 denotes protein
T1969 5046-5053 PR:000000001 denotes protein
T1970 5046-5053 GO:0003675 denotes protein
T1971 5046-5053 SO:0000104 denotes protein
T1972 5068-5071 C039556 denotes Id2
T1973 5068-5071 C039556 denotes Id2
T1974 5068-5071 PR:000000040 denotes Id2
T1975 5068-5071 PR:P41137 denotes Id2
T1976 5068-5071 PR:Q02363 denotes Id2
T1977 5068-5071 PR:P41136 denotes Id2
T1978 5076-5079 PR:P41133 denotes Id3
T1979 5076-5079 PR:P41138 denotes Id3
T1980 5076-5079 PR:Q02535 denotes Id3
T1981 5076-5079 PR:000000041 denotes Id3
T1982 5104-5112 CHEBI:36080 denotes proteins
T1983 5147-5160 UBERON:2000098 denotes proliferation
T1984 5195-5203 CHEBI:36080 denotes proteins
T1985 5211-5228 SO:0002052 denotes dominant-negative
T1986 5229-5239 CHEBI:35222 denotes inhibitors
T1987 5245-5253 CHEBI:36080 denotes proteins
T1988 5258-5262 PR:Q02650 denotes Pax5
T1989 5258-5262 PR:000001903 denotes Pax5
T1990 5258-5262 PR:Q02548 denotes Pax5
T1991 5301-5309 CHEBI:36080 denotes proteins
T1992 5338-5341 CHEBI:16991 denotes DNA
T1993 5338-5341 D004247 denotes DNA
T1994 5338-5341 SO:0000352 denotes DNA
T1995 5338-5341 GO:0005574 denotes DNA
T1996 5389-5397 CHEBI:36080 denotes proteins
T1997 5399-5403 PR:Q02650 denotes Pax5
T1998 5399-5403 PR:000001903 denotes Pax5
T1999 5399-5403 PR:Q02548 denotes Pax5
T2000 5411-5419 CHEBI:36080 denotes proteins
T2001 5495-5503 CHEBI:36080 denotes proteins
T2002 5613-5623 CL:0000542 denotes lymphocyte
T2003 5613-5635 GO:0030098 denotes lymphocyte development
T2004 5693-5698 D055418 denotes BMP-6
T2005 5693-5698 D055418 denotes BMP-6
T2006 5693-5698 Q04906 denotes BMP-6
T2007 5693-5698 PR:000000167 denotes BMP-6
T2008 5693-5698 P20722 denotes BMP-6
T2009 5693-5698 PR:Q04906 denotes BMP-6
T2010 5693-5698 P22004 denotes BMP-6
T2011 5693-5698 PR:P22004 denotes BMP-6
T2012 5693-5698 PR:P20722 denotes BMP-6
T2013 5743-5746 PR:P41134 denotes Id1
T2014 5743-5746 PR:P20067 denotes Id1
T2015 5743-5746 PR:P41135 denotes Id1
T2016 5743-5746 PR:000000039 denotes Id1
T2017 5747-5754 CHEBI:36080 denotes protein
T2018 5747-5754 CHEBI:11122 denotes protein
T2019 5747-5754 PR:000000001 denotes protein
T2020 5747-5754 GO:0003675 denotes protein
T2021 5747-5754 SO:0000104 denotes protein
T2022 5798-5806 CHEBI:36080 denotes proteins
T2023 5859-5868 GO:0097194 denotes apoptosis
T2024 5859-5868 GO:0006915 denotes apoptosis
T2025 5872-5884 CL:0000236 denotes B-lymphocyte
T2026 5900-5905 D016212 denotes TGF-β
T2027 5900-5905 D016212 denotes TGF-β
T2028 5900-5905 PR:000000046 denotes TGF-β
T2029 5928-5936 CHEBI:36080 denotes proteins
T2030 5969-5979 GO:0023052 denotes signalling
T2031 6014-6024 GO:0007049 denotes cell cycle
T2032 6014-6024 UBERON:2000098 denotes cell cycle
T2033 6029-6042 D063646 denotes tumorigenesis
T2034 6029-6042 D063646 denotes tumorigenesis
T2035 6142-6147 D006801 denotes human
T2036 6171-6174 PR:P41134 denotes Id1
T2037 6171-6174 PR:P20067 denotes Id1
T2038 6171-6174 PR:P41135 denotes Id1
T2039 6171-6174 PR:000000039 denotes Id1
T2040 6249-6254 D006801 denotes human
T2041 6255-6267 D009369 denotes malignancies
T2042 6255-6267 D009369 denotes malignancies
T2043 6284-6300 D009101 denotes multiple myeloma
T2044 6284-6300 D009101 denotes multiple myeloma
T2045 6342-6347 D055418 denotes BMP-6
T2046 6342-6347 D055418 denotes BMP-6
T2047 6342-6347 Q04906 denotes BMP-6
T2048 6342-6347 PR:000000167 denotes BMP-6
T2049 6342-6347 P20722 denotes BMP-6
T2050 6342-6347 PR:Q04906 denotes BMP-6
T2051 6342-6347 P22004 denotes BMP-6
T2052 6342-6347 PR:P22004 denotes BMP-6
T2053 6342-6347 PR:P20722 denotes BMP-6
T2054 6358-6371 GO:0005622 denotes intracellular
T2055 6372-6382 GO:0023052 denotes signalling
T2056 6395-6400 D006801 denotes human
T2057 6466-6474 D008223 denotes lymphoma
T2058 6466-6474 D008223 denotes lymphoma
T2059 6479-6491 GO:0006954 denotes inflammation
T2060 6479-6491 D007249 denotes inflammation
T2061 6479-6491 D007249 denotes inflammation
T2062 6498-6503 D055418 denotes BMP-6
T2063 6498-6503 D055418 denotes BMP-6
T2064 6498-6503 Q04906 denotes BMP-6
T2065 6498-6503 PR:000000167 denotes BMP-6
T2066 6498-6503 P20722 denotes BMP-6
T2067 6498-6503 PR:Q04906 denotes BMP-6
T2068 6498-6503 P22004 denotes BMP-6
T2069 6498-6503 PR:P22004 denotes BMP-6
T2070 6498-6503 PR:P20722 denotes BMP-6
T2071 6504-6508 D012333 denotes mRNA
T2072 6504-6508 CHEBI:33699 denotes mRNA
T2073 6504-6508 SO:0000234 denotes mRNA
T2074 6650-6653 PR:P41134 denotes Id1
T2075 6650-6653 PR:P20067 denotes Id1
T2076 6650-6653 PR:P41135 denotes Id1
T2077 6650-6653 PR:000000039 denotes Id1
T2078 6654-6658 Q7SY53 denotes to B
T2079 6692-6698 CL:0000236 denotes B cell
T2080 6692-6710 GO:0030183 denotes B cell development
T2081 6720-6729 GO:0097194 denotes apoptosis
T2082 6720-6729 GO:0006915 denotes apoptosis
T2083 6761-6767 CL:0000236 denotes B cell
T2084 6761-6777 D016393 denotes B cell lymphomas
T2085 6761-6777 D016393 denotes B cell lymphomas
T2086 6794-6799 D055418 denotes BMP-6
T2087 6794-6799 D055418 denotes BMP-6
T2088 6794-6799 Q04906 denotes BMP-6
T2089 6794-6799 PR:000000167 denotes BMP-6
T2090 6794-6799 P20722 denotes BMP-6
T2091 6794-6799 PR:Q04906 denotes BMP-6
T2092 6794-6799 P22004 denotes BMP-6
T2093 6794-6799 PR:P22004 denotes BMP-6
T2094 6794-6799 PR:P20722 denotes BMP-6
T2095 6837-6857 D001172 denotes rheumatoid arthritis
T2096 6837-6857 D001172 denotes rheumatoid arthritis
T2097 6894-6897 PR:P41134 denotes Id1
T2098 6894-6897 PR:P20067 denotes Id1
T2099 6894-6897 PR:P41135 denotes Id1
T2100 6894-6897 PR:000000039 denotes Id1
T2101 6902-6905 PR:P41133 denotes Id3
T2102 6902-6905 PR:P41138 denotes Id3
T2103 6902-6905 PR:Q02535 denotes Id3
T2104 6902-6905 PR:000000041 denotes Id3
T2105 7018-7026 CHEBI:36080 denotes proteins
T2106 7034-7044 GO:0065007 denotes regulation
T2107 7055-7061 CL:0000236 denotes B cell
T2108 7055-7073 GO:0001782 denotes B cell homeostasis
T2109 7183-7187 PR:P41134 denotes Id-1
T2110 7183-7187 PR:P20067 denotes Id-1
T2111 7183-7187 PR:P41135 denotes Id-1
T2112 7183-7187 PR:000000039 denotes Id-1
T2113 7191-7196 D006801 denotes human
T2114 7251-7255 PR:P41134 denotes Id-1
T2115 7251-7255 PR:P20067 denotes Id-1
T2116 7251-7255 PR:P41135 denotes Id-1
T2117 7251-7255 PR:000000039 denotes Id-1
T2118 7256-7260 SO:0000704 denotes gene
T2119 7256-7271 GO:0010467 denotes gene expression
T2120 7291-7296 D055418 denotes BMP-6
T2121 7291-7296 D055418 denotes BMP-6
T2122 7291-7296 Q04906 denotes BMP-6
T2123 7291-7296 PR:000000167 denotes BMP-6
T2124 7291-7296 P20722 denotes BMP-6
T2125 7291-7296 PR:Q04906 denotes BMP-6
T2126 7291-7296 P22004 denotes BMP-6
T2127 7291-7296 PR:P22004 denotes BMP-6
T2128 7291-7296 PR:P20722 denotes BMP-6
T2129 7307-7312 D006801 denotes human
T2130 7358-7363 D055418 denotes BMP-6
T2131 7358-7363 D055418 denotes BMP-6
T2132 7358-7363 Q04906 denotes BMP-6
T2133 7358-7363 PR:000000167 denotes BMP-6
T2134 7358-7363 P20722 denotes BMP-6
T2135 7358-7363 PR:Q04906 denotes BMP-6
T2136 7358-7363 P22004 denotes BMP-6
T2137 7358-7363 PR:P22004 denotes BMP-6
T2138 7358-7363 PR:P20722 denotes BMP-6
T2139 7435-7441 GO:0007613 denotes memory
T2140 7491-7504 CL:0000785 denotes mature B cell
T2141 7519-7524 D055418 denotes BMP-6
T2142 7519-7524 D055418 denotes BMP-6
T2143 7519-7524 Q04906 denotes BMP-6
T2144 7519-7524 PR:000000167 denotes BMP-6
T2145 7519-7524 P20722 denotes BMP-6
T2146 7519-7524 PR:Q04906 denotes BMP-6
T2147 7519-7524 P22004 denotes BMP-6
T2148 7519-7524 PR:P22004 denotes BMP-6
T2149 7519-7524 PR:P20722 denotes BMP-6
T2150 7525-7529 D012333 denotes mRNA
T2151 7525-7529 CHEBI:33699 denotes mRNA
T2152 7525-7529 SO:0000234 denotes mRNA
T2153 7571-7575 SO:0000704 denotes gene
T2154 7571-7586 GO:0010467 denotes gene expression
T2155 7630-7635 D055418 denotes BMP-6
T2156 7630-7635 D055418 denotes BMP-6
T2157 7630-7635 Q04906 denotes BMP-6
T2158 7630-7635 PR:000000167 denotes BMP-6
T2159 7630-7635 P20722 denotes BMP-6
T2160 7630-7635 PR:Q04906 denotes BMP-6
T2161 7630-7635 P22004 denotes BMP-6
T2162 7630-7635 PR:P22004 denotes BMP-6
T2163 7630-7635 PR:P20722 denotes BMP-6
T2164 7730-7735 D055418 denotes BMP-6
T2165 7730-7735 D055418 denotes BMP-6
T2166 7730-7735 Q04906 denotes BMP-6
T2167 7730-7735 PR:000000167 denotes BMP-6
T2168 7730-7735 P20722 denotes BMP-6
T2169 7730-7735 PR:Q04906 denotes BMP-6
T2170 7730-7735 P22004 denotes BMP-6
T2171 7730-7735 PR:P22004 denotes BMP-6
T2172 7730-7735 PR:P20722 denotes BMP-6
T2173 7796-7803 UBERON:0000992 denotes ovarium
T2174 7881-7886 D055418 denotes BMP-6
T2175 7881-7886 D055418 denotes BMP-6
T2176 7881-7886 Q04906 denotes BMP-6
T2177 7881-7886 PR:000000167 denotes BMP-6
T2178 7881-7886 P20722 denotes BMP-6
T2179 7881-7886 PR:Q04906 denotes BMP-6
T2180 7881-7886 P22004 denotes BMP-6
T2181 7881-7886 PR:P22004 denotes BMP-6
T2182 7881-7886 PR:P20722 denotes BMP-6
T2183 7895-7900 D006801 denotes human
T2184 7937-7942 D055418 denotes BMP-6
T2185 7937-7942 D055418 denotes BMP-6
T2186 7937-7942 Q04906 denotes BMP-6
T2187 7937-7942 PR:000000167 denotes BMP-6
T2188 7937-7942 P20722 denotes BMP-6
T2189 7937-7942 PR:Q04906 denotes BMP-6
T2190 7937-7942 P22004 denotes BMP-6
T2191 7937-7942 PR:P22004 denotes BMP-6
T2192 7937-7942 PR:P20722 denotes BMP-6
T2193 7943-7947 D012333 denotes mRNA
T2194 7943-7947 CHEBI:33699 denotes mRNA
T2195 7943-7947 SO:0000234 denotes mRNA
T2196 7989-7992 Q41249 denotes PCR
T2197 7989-7992 O66148 denotes PCR
T2198 7989-7992 Q59987 denotes PCR
T2199 7989-7992 Q01289 denotes PCR
T2200 7989-7992 O80333 denotes PCR
T2201 7989-7992 P15904 denotes PCR
T2202 7989-7992 Q9SDT1 denotes PCR
T2203 7989-7992 Q39617 denotes PCR
T2204 8041-8046 D055418 denotes BMP-6
T2205 8041-8046 D055418 denotes BMP-6
T2206 8041-8046 Q04906 denotes BMP-6
T2207 8041-8046 PR:000000167 denotes BMP-6
T2208 8041-8046 P20722 denotes BMP-6
T2209 8041-8046 PR:Q04906 denotes BMP-6
T2210 8041-8046 P22004 denotes BMP-6
T2211 8041-8046 PR:P22004 denotes BMP-6
T2212 8041-8046 PR:P20722 denotes BMP-6
T2213 8087-8092 D006801 denotes human
T2214 8096-8101 UBERON:0001977 denotes serum
T2215 8125-8133 C044203 denotes anti-IgM
T2216 8166-8171 D055418 denotes BMP-6
T2217 8166-8171 D055418 denotes BMP-6
T2218 8166-8171 Q04906 denotes BMP-6
T2219 8166-8171 PR:000000167 denotes BMP-6
T2220 8166-8171 P20722 denotes BMP-6
T2221 8166-8171 PR:Q04906 denotes BMP-6
T2222 8166-8171 P22004 denotes BMP-6
T2223 8166-8171 PR:P22004 denotes BMP-6
T2224 8166-8171 PR:P20722 denotes BMP-6
T2225 8172-8179 CHEBI:36080 denotes protein
T2226 8172-8179 CHEBI:11122 denotes protein
T2227 8172-8179 PR:000000001 denotes protein
T2228 8172-8179 GO:0003675 denotes protein
T2229 8172-8179 SO:0000104 denotes protein
T2230 8237-8244 SO:0100018 denotes binding
T2231 8237-8244 SO:0001091 denotes binding
T2232 8237-8244 GO:0005488 denotes binding
T2233 8257-8262 D055418 denotes BMP-6
T2234 8257-8262 D055418 denotes BMP-6
T2235 8257-8262 Q04906 denotes BMP-6
T2236 8257-8262 PR:000000167 denotes BMP-6
T2237 8257-8262 P20722 denotes BMP-6
T2238 8257-8262 PR:Q04906 denotes BMP-6
T2239 8257-8262 P22004 denotes BMP-6
T2240 8257-8262 PR:P22004 denotes BMP-6
T2241 8257-8262 PR:P20722 denotes BMP-6
T2242 8263-8273 D000906 denotes antibodies
T2243 8286-8290 PR:Q9V853 denotes lack
T2244 8346-8351 D055418 denotes BMP-6
T2245 8346-8351 D055418 denotes BMP-6
T2246 8346-8351 Q04906 denotes BMP-6
T2247 8346-8351 PR:000000167 denotes BMP-6
T2248 8346-8351 P20722 denotes BMP-6
T2249 8346-8351 PR:Q04906 denotes BMP-6
T2250 8346-8351 P22004 denotes BMP-6
T2251 8346-8351 PR:P22004 denotes BMP-6
T2252 8346-8351 PR:P20722 denotes BMP-6
T2253 8352-8356 D012333 denotes mRNA
T2254 8352-8356 CHEBI:33699 denotes mRNA
T2255 8352-8356 SO:0000234 denotes mRNA
T2256 8387-8394 GO:0003675 denotes protein
T2257 8387-8394 CHEBI:36080 denotes protein
T2258 8387-8394 CHEBI:11122 denotes protein
T2259 8387-8394 PR:000000001 denotes protein
T2260 8387-8394 SO:0000104 denotes protein
T2261 8466-8471 D055418 denotes BMP-6
T2262 8466-8471 D055418 denotes BMP-6
T2263 8466-8471 Q04906 denotes BMP-6
T2264 8466-8471 PR:000000167 denotes BMP-6
T2265 8466-8471 P20722 denotes BMP-6
T2266 8466-8471 PR:Q04906 denotes BMP-6
T2267 8466-8471 P22004 denotes BMP-6
T2268 8466-8471 PR:P22004 denotes BMP-6
T2269 8466-8471 PR:P20722 denotes BMP-6
T2270 8472-8479 CHEBI:36080 denotes protein
T2271 8472-8479 CHEBI:11122 denotes protein
T2272 8472-8479 PR:000000001 denotes protein
T2273 8472-8479 GO:0003675 denotes protein
T2274 8472-8479 SO:0000104 denotes protein
T2275 8520-8526 UBERON:0000479 denotes tissue
T2276 8547-8552 D055418 denotes BMP-6
T2277 8547-8552 D055418 denotes BMP-6
T2278 8547-8552 Q04906 denotes BMP-6
T2279 8547-8552 PR:000000167 denotes BMP-6
T2280 8547-8552 P20722 denotes BMP-6
T2281 8547-8552 PR:Q04906 denotes BMP-6
T2282 8547-8552 P22004 denotes BMP-6
T2283 8547-8552 PR:P22004 denotes BMP-6
T2284 8547-8552 PR:P20722 denotes BMP-6
T2285 8567-8572 D006801 denotes human
T2286 8643-8648 D055418 denotes BMP-6
T2287 8643-8648 D055418 denotes BMP-6
T2288 8643-8648 Q04906 denotes BMP-6
T2289 8643-8648 PR:000000167 denotes BMP-6
T2290 8643-8648 P20722 denotes BMP-6
T2291 8643-8648 PR:Q04906 denotes BMP-6
T2292 8643-8648 P22004 denotes BMP-6
T2293 8643-8648 PR:P22004 denotes BMP-6
T2294 8643-8648 PR:P20722 denotes BMP-6
T2295 8652-8657 10090 denotes mouse
T2296 8652-8657 D051379 denotes mouse
T2297 8684-8695 UBERON:0002371 denotes bone marrow
T2298 8684-8695 D001855 denotes bone marrow
T2299 8684-8695 D001855 denotes bone marrow
T2300 8699-8703 PR:000005054 denotes mice
T2301 8699-8703 O89094 denotes mice
T2302 8699-8703 D051379 denotes mice
T2303 8699-8703 10095 denotes mice
T2304 8722-8731 D001168 denotes arthritis
T2305 8722-8731 D001168 denotes arthritis
T2306 8801-8810 D001168 denotes arthritis
T2307 8801-8810 D001168 denotes arthritis
T2308 8850-8855 D055418 denotes BMP-6
T2309 8850-8855 D055418 denotes BMP-6
T2310 8850-8855 Q04906 denotes BMP-6
T2311 8850-8855 PR:000000167 denotes BMP-6
T2312 8850-8855 P20722 denotes BMP-6
T2313 8850-8855 PR:Q04906 denotes BMP-6
T2314 8850-8855 P22004 denotes BMP-6
T2315 8850-8855 PR:P22004 denotes BMP-6
T2316 8850-8855 PR:P20722 denotes BMP-6
T2317 8874-8877 D007075 denotes IgM
T2318 8939-8944 PR:000000046 denotes TGF-β
T2319 8939-8944 D016212 denotes TGF-β
T2320 8939-8944 D016212 denotes TGF-β
T2321 9164-9178 D063646 denotes carcinogenesis
T2322 9164-9178 D063646 denotes carcinogenesis
T2323 9180-9185 D055418 denotes BMP-6
T2324 9180-9185 D055418 denotes BMP-6
T2325 9180-9185 Q04906 denotes BMP-6
T2326 9180-9185 PR:000000167 denotes BMP-6
T2327 9180-9185 P20722 denotes BMP-6
T2328 9180-9185 PR:Q04906 denotes BMP-6
T2329 9180-9185 P22004 denotes BMP-6
T2330 9180-9185 PR:P22004 denotes BMP-6
T2331 9180-9185 PR:P20722 denotes BMP-6
T2332 9202-9210 SO:0000167 denotes promoter
T2333 9336-9341 PR:000000046 denotes TGF-β
T2334 9336-9341 D016212 denotes TGF-β
T2335 9336-9341 D016212 denotes TGF-β
T2336 9368-9374 PR:000000182 denotes TGF-β1
T2337 9368-9374 D053773 denotes TGF-β1
T2338 9368-9374 D053773 denotes TGF-β1
T2339 9379-9382 CHEBI:60815 denotes BMP
T2340 9379-9384 O46576 denotes BMP-4
T2341 9379-9384 Q8MJV5 denotes BMP-4
T2342 9379-9384 PR:Q06826 denotes BMP-4
T2343 9379-9384 P12644 denotes BMP-4
T2344 9379-9384 PR:P12644 denotes BMP-4
T2345 9379-9384 P30885 denotes BMP-4
T2346 9379-9384 PR:000000165 denotes BMP-4
T2347 9379-9384 Q90752 denotes BMP-4
T2348 9379-9384 Q06826 denotes BMP-4
T2349 9379-9384 PR:P21275 denotes BMP-4
T2350 9379-9384 Q29607 denotes BMP-4
T2351 9379-9384 Q2KJH1 denotes BMP-4
T2352 9379-9384 P21275 denotes BMP-4
T2353 9431-9434 PR:000000034 denotes BMP
T2354 9431-9434 P35855 denotes BMP
T2355 9431-9434 CHEBI:60815 denotes BMP
T2356 9525-9530 D055418 denotes BMP-6
T2357 9525-9530 D055418 denotes BMP-6
T2358 9525-9530 Q04906 denotes BMP-6
T2359 9525-9530 PR:000000167 denotes BMP-6
T2360 9525-9530 P20722 denotes BMP-6
T2361 9525-9530 PR:Q04906 denotes BMP-6
T2362 9525-9530 P22004 denotes BMP-6
T2363 9525-9530 PR:P22004 denotes BMP-6
T2364 9525-9530 PR:P20722 denotes BMP-6
T2365 9531-9541 SO:0000673 denotes transcript
T2366 9581-9586 D055418 denotes BMP-6
T2367 9581-9586 D055418 denotes BMP-6
T2368 9581-9586 Q04906 denotes BMP-6
T2369 9581-9586 PR:000000167 denotes BMP-6
T2370 9581-9586 P20722 denotes BMP-6
T2371 9581-9586 PR:Q04906 denotes BMP-6
T2372 9581-9586 P22004 denotes BMP-6
T2373 9581-9586 PR:P22004 denotes BMP-6
T2374 9581-9586 PR:P20722 denotes BMP-6
T2375 9602-9607 D006801 denotes human
T2376 9625-9628 PR:000001004 denotes CD4
T2377 9625-9628 PR:P06332 denotes CD4
T2378 9625-9628 PR:P05540 denotes CD4
T2379 9625-9628 PR:P01730 denotes CD4
T2380 9692-9696 PR:P31041 denotes CD28
T2381 9692-9696 PR:P31043 denotes CD28
T2382 9692-9696 PR:P10747 denotes CD28
T2383 9692-9696 PR:000001841 denotes CD28
T2384 9692-9696 PR:P31042 denotes CD28
T2385 9703-9712 32644 denotes not shown
T2386 9747-9753 CL:0000084 denotes T cell
T2387 9780-9784 PR:000005054 denotes mice
T2388 9780-9784 O89094 denotes mice
T2389 9780-9784 D051379 denotes mice
T2390 9780-9784 10095 denotes mice
T2391 9807-9812 D055418 denotes BMP-6
T2392 9807-9812 D055418 denotes BMP-6
T2393 9807-9812 Q04906 denotes BMP-6
T2394 9807-9812 PR:000000167 denotes BMP-6
T2395 9807-9812 P20722 denotes BMP-6
T2396 9807-9812 PR:Q04906 denotes BMP-6
T2397 9807-9812 P22004 denotes BMP-6
T2398 9807-9812 PR:P22004 denotes BMP-6
T2399 9807-9812 PR:P20722 denotes BMP-6
T2400 9876-9889 D007154 denotes immune system
T2401 9876-9889 D007154 denotes immune system
T2402 9876-9889 UBERON:0002405 denotes immune system
T2403 9893-9899 UBERON:0000479 denotes tissue
T2404 9920-9940 UBERON:0002390 denotes hematopoietic system
T2405 9973-9978 D055418 denotes BMP-6
T2406 9973-9978 D055418 denotes BMP-6
T2407 9973-9978 Q04906 denotes BMP-6
T2408 9973-9978 PR:000000167 denotes BMP-6
T2409 9973-9978 P20722 denotes BMP-6
T2410 9973-9978 PR:Q04906 denotes BMP-6
T2411 9973-9978 P22004 denotes BMP-6
T2412 9973-9978 PR:P22004 denotes BMP-6
T2413 9973-9978 PR:P20722 denotes BMP-6
T2414 9997-10002 D006801 denotes human
T2415 10003-10007 UBERON:0001474 denotes bone
T2416 10003-10007 UBERON:0002481 denotes bone
T2417 10012-10023 D001855 denotes bone marrow
T2418 10012-10023 D001855 denotes bone marrow
T2419 10012-10030 UBERON:0007195 denotes bone marrow stroma
T2420 10074-10079 D006801 denotes human
T2421 10080-10094 UBERON:0002066 denotes umbilical vein
T2422 10114-10119 CVCL_2959 denotes HUVEC
T2423 10136-10141 D055418 denotes BMP-6
T2424 10136-10141 D055418 denotes BMP-6
T2425 10136-10141 Q04906 denotes BMP-6
T2426 10136-10141 PR:000000167 denotes BMP-6
T2427 10136-10141 P20722 denotes BMP-6
T2428 10136-10141 PR:Q04906 denotes BMP-6
T2429 10136-10141 P22004 denotes BMP-6
T2430 10136-10141 PR:P22004 denotes BMP-6
T2431 10136-10141 PR:P20722 denotes BMP-6
T2432 10142-10146 D012333 denotes mRNA
T2433 10142-10146 CHEBI:33699 denotes mRNA
T2434 10142-10146 SO:0000234 denotes mRNA
T2435 10166-10177 UBERON:0001986 denotes endothelium
T2436 10207-10212 D055418 denotes BMP-6
T2437 10207-10212 D055418 denotes BMP-6
T2438 10207-10212 Q04906 denotes BMP-6
T2439 10207-10212 PR:000000167 denotes BMP-6
T2440 10207-10212 P20722 denotes BMP-6
T2441 10207-10212 PR:Q04906 denotes BMP-6
T2442 10207-10212 P22004 denotes BMP-6
T2443 10207-10212 PR:P22004 denotes BMP-6
T2444 10207-10212 PR:P20722 denotes BMP-6
T2445 10256-10261 D055418 denotes BMP-6
T2446 10256-10261 D055418 denotes BMP-6
T2447 10256-10261 Q04906 denotes BMP-6
T2448 10256-10261 PR:000000167 denotes BMP-6
T2449 10256-10261 P20722 denotes BMP-6
T2450 10256-10261 PR:Q04906 denotes BMP-6
T2451 10256-10261 P22004 denotes BMP-6
T2452 10256-10261 PR:P22004 denotes BMP-6
T2453 10256-10261 PR:P20722 denotes BMP-6
T2454 10304-10309 D055418 denotes BMP-6
T2455 10304-10309 D055418 denotes BMP-6
T2456 10304-10309 Q04906 denotes BMP-6
T2457 10304-10309 PR:000000167 denotes BMP-6
T2458 10304-10309 P20722 denotes BMP-6
T2459 10304-10309 PR:Q04906 denotes BMP-6
T2460 10304-10309 P22004 denotes BMP-6
T2461 10304-10309 PR:P22004 denotes BMP-6
T2462 10304-10309 PR:P20722 denotes BMP-6
T2463 10310-10314 D012333 denotes mRNA
T2464 10310-10314 CHEBI:33699 denotes mRNA
T2465 10310-10314 SO:0000234 denotes mRNA
T2466 10347-10357 CL:0000235 denotes macrophage
T2467 10435-10440 D006801 denotes human
T2468 10455-10465 CL:0000775 denotes neutrophil
T2469 10530-10535 D055418 denotes BMP-6
T2470 10530-10535 D055418 denotes BMP-6
T2471 10530-10535 Q04906 denotes BMP-6
T2472 10530-10535 PR:000000167 denotes BMP-6
T2473 10530-10535 P20722 denotes BMP-6
T2474 10530-10535 PR:Q04906 denotes BMP-6
T2475 10530-10535 P22004 denotes BMP-6
T2476 10530-10535 PR:P22004 denotes BMP-6
T2477 10530-10535 PR:P20722 denotes BMP-6
T2478 10536-10546 SO:0000673 denotes transcript
T2479 10606-10611 D055418 denotes BMP-6
T2480 10606-10611 D055418 denotes BMP-6
T2481 10606-10611 Q04906 denotes BMP-6
T2482 10606-10611 PR:000000167 denotes BMP-6
T2483 10606-10611 P20722 denotes BMP-6
T2484 10606-10611 PR:Q04906 denotes BMP-6
T2485 10606-10611 P22004 denotes BMP-6
T2486 10606-10611 PR:P22004 denotes BMP-6
T2487 10606-10611 PR:P20722 denotes BMP-6
T2488 10626-10631 D006801 denotes human