PMC:1064895 / 2420-2921 JSONTXT

{"project":"test3","denotations":[{"id":"T2189","span":{"begin":342,"end":360},"obj":"Protein"},{"id":"T2188","span":{"begin":307,"end":336},"obj":"Protein"},{"id":"T2187","span":{"begin":293,"end":303},"obj":"Negative_regulation"},{"id":"T2155","span":{"begin":342,"end":360},"obj":"Protein"},{"id":"T2154","span":{"begin":307,"end":336},"obj":"Protein"}],"relations":[{"id":"R1090","pred":"themeOf","subj":"T2188","obj":"T2187"},{"id":"R1091","pred":"themeOf","subj":"T2189","obj":"T2187"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"BioNLP16_Messiy","denotations":[{"id":"T3714","span":{"begin":342,"end":360},"obj":"Protein"},{"id":"T3713","span":{"begin":307,"end":336},"obj":"Protein"},{"id":"T3746","span":{"begin":293,"end":303},"obj":"Negative_regulation"}],"relations":[{"id":"R1776","pred":"themeOf","subj":"T3713","obj":"T3746"},{"id":"R1777","pred":"themeOf","subj":"T3714","obj":"T3746"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"BioNLP16_DUT","denotations":[{"id":"T4635","span":{"begin":293,"end":303},"obj":"Negative_regulation"},{"id":"T4603","span":{"begin":342,"end":360},"obj":"Protein"},{"id":"T4602","span":{"begin":307,"end":336},"obj":"Protein"}],"relations":[{"id":"R2458","pred":"themeOf","subj":"T4602","obj":"T4635"},{"id":"R2459","pred":"themeOf","subj":"T4603","obj":"T4635"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"2_test","denotations":[{"id":"15642134-12810425-4202008","span":{"begin":243,"end":244},"obj":"12810425"},{"id":"15642134-12810200-4202009","span":{"begin":498,"end":499},"obj":"12810200"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"biosemtest","denotations":[{"id":"T2741","span":{"begin":473,"end":484},"obj":"UMLS/C0302350"},{"id":"T2738","span":{"begin":307,"end":328},"obj":"UP/P13296"},{"id":"T2734","span":{"begin":229,"end":235},"obj":"UMLS/C0444497"},{"id":"T2733","span":{"begin":96,"end":101},"obj":"UMLS/C0444497"},{"id":"T2717","span":{"begin":261,"end":269},"obj":"UMLS/C0205210"},{"id":"T2711","span":{"begin":307,"end":328},"obj":"UP/P59694"},{"id":"T2704","span":{"begin":307,"end":328},"obj":"UP/P19101"},{"id":"T2697","span":{"begin":469,"end":472},"obj":"UMLS/C0205314"},{"id":"T2693","span":{"begin":185,"end":190},"obj":"UMLS/C0205309"},{"id":"T2692","span":{"begin":307,"end":328},"obj":"UP/O77764"},{"id":"T2691","span":{"begin":261,"end":269},"obj":"UMLS/C1555900"},{"id":"T2688","span":{"begin":307,"end":328},"obj":"UP/P51435"},{"id":"T2678","span":{"begin":307,"end":328},"obj":"UP/Q8MKG8"},{"id":"T2676","span":{"begin":63,"end":74},"obj":"UMLS/C0024432"},{"id":"T2672","span":{"begin":175,"end":180},"obj":"UMLS/C0007634"},{"id":"T2671","span":{"begin":307,"end":328},"obj":"UP/P59684"},{"id":"T2665","span":{"begin":485,"end":497},"obj":"UMLS/C0870325"},{"id":"T2664","span":{"begin":261,"end":269},"obj":"UMLS/C1611832"},{"id":"T2657","span":{"begin":307,"end":328},"obj":"UP/P36939"},{"id":"T2656","span":{"begin":307,"end":328},"obj":"UP/Q8JFG3"},{"id":"T2653","span":{"begin":116,"end":127},"obj":"UMLS/C0020507"},{"id":"T2647","span":{"begin":307,"end":328},"obj":"UP/P33620"},{"id":"T2642","span":{"begin":307,"end":328},"obj":"UP/P79374"},{"id":"T2641","span":{"begin":107,"end":115},"obj":"UMLS/C1550315"},{"id":"T2640","span":{"begin":155,"end":163},"obj":"UMLS/C0439180"},{"id":"T2637","span":{"begin":307,"end":328},"obj":"UP/Q06599"},{"id":"T2636","span":{"begin":307,"end":328},"obj":"UP/P59695"},{"id":"T2635","span":{"begin":307,"end":328},"obj":"UP/P79337"},{"id":"T2633","span":{"begin":307,"end":328},"obj":"UP/P59693"},{"id":"T2632","span":{"begin":307,"end":328},"obj":"UP/O35734"},{"id":"T2627","span":{"begin":155,"end":163},"obj":"UMLS/C0680255"},{"id":"T2624","span":{"begin":261,"end":269},"obj":"UMLS/C1608518"},{"id":"T2623","span":{"begin":307,"end":328},"obj":"UP/P29553"},{"id":"T2622","span":{"begin":307,"end":328},"obj":"UP/P23563"},{"id":"T2621","span":{"begin":307,"end":328},"obj":"UP/Q8HZD9"},{"id":"T2603","span":{"begin":391,"end":394},"obj":"UMLS/C1554080"},{"id":"T2593","span":{"begin":229,"end":235},"obj":"UMLS/C1706309"},{"id":"T2592","span":{"begin":96,"end":101},"obj":"UMLS/C1706309"},{"id":"T2587","span":{"begin":63,"end":74},"obj":"UMLS/C1550652"},{"id":"T2584","span":{"begin":307,"end":328},"obj":"UP/P23383"},{"id":"T2575","span":{"begin":307,"end":328},"obj":"UP/Q1G1A2"},{"id":"T2573","span":{"begin":46,"end":59},"obj":"UMLS/C0332448"},{"id":"T2568","span":{"begin":307,"end":328},"obj":"UP/Q8WNR1"},{"id":"T2561","span":{"begin":307,"end":328},"obj":"UMLS/C1456820"},{"id":"T2559","span":{"begin":307,"end":328},"obj":"UP/Q9BEA1"},{"id":"T2558","span":{"begin":485,"end":497},"obj":"UMLS/C2347934"},{"id":"T2556","span":{"begin":307,"end":328},"obj":"UP/Q19LH4"},{"id":"T2555","span":{"begin":29,"end":42},"obj":"UMLS/C1880022"},{"id":"T2541","span":{"begin":469,"end":472},"obj":"UMLS/C1553390"},{"id":"T2479","span":{"begin":175,"end":180},"obj":"UMLS/C1136359"},{"id":"T2475","span":{"begin":279,"end":287},"obj":"UMLS/C1706701"},{"id":"T2474","span":{"begin":307,"end":328},"obj":"UMLS/C2700093"},{"id":"T2472","span":{"begin":270,"end":278},"obj":"UMLS/C0814225"},{"id":"T2470","span":{"begin":485,"end":497},"obj":"UMLS/C0185125"},{"id":"T2466","span":{"begin":175,"end":180},"obj":"UMLS/C1948049"},{"id":"T2465","span":{"begin":307,"end":328},"obj":"UP/Q2MH05"},{"id":"T2464","span":{"begin":293,"end":303},"obj":"UMLS/C1999216"},{"id":"T2463","span":{"begin":307,"end":328},"obj":"UMLS/C0041368"},{"id":"T2458","span":{"begin":307,"end":328},"obj":"UP/Q539C2"},{"id":"T2453","span":{"begin":0,"end":20},"obj":"UMLS/C0003873"},{"id":"T2447","span":{"begin":473,"end":484},"obj":"UMLS/C1553525"},{"id":"T2442","span":{"begin":214,"end":225},"obj":"UMLS/C1948029"},{"id":"T2438","span":{"begin":279,"end":287},"obj":"UMLS/C1301820"},{"id":"T2437","span":{"begin":155,"end":163},"obj":"UMLS/C1963578"},{"id":"T2435","span":{"begin":454,"end":465},"obj":"UMLS/C1527148"},{"id":"T2433","span":{"begin":63,"end":74},"obj":"UMLS/C1546706"},{"id":"T2428","span":{"begin":307,"end":328},"obj":"UP/P04924"},{"id":"T2427","span":{"begin":307,"end":328},"obj":"UP/P01375"},{"id":"T2420","span":{"begin":307,"end":328},"obj":"UP/P16599"},{"id":"T2412","span":{"begin":408,"end":417},"obj":"UMLS/C1524094"},{"id":"T2411","span":{"begin":145,"end":154},"obj":"UMLS/C1524094"},{"id":"T2403","span":{"begin":469,"end":472},"obj":"UMLS/C1578513"},{"id":"T2395","span":{"begin":343,"end":354},"obj":"UMLS/C0021764"},{"id":"T2381","span":{"begin":391,"end":394},"obj":"UMLS/C1706198"},{"id":"T2372","span":{"begin":307,"end":328},"obj":"UP/P51743"},{"id":"T2358","span":{"begin":175,"end":180},"obj":"UMLS/C1704653"},{"id":"T2345","span":{"begin":379,"end":387},"obj":"UMLS/C0332206"},{"id":"T2335","span":{"begin":307,"end":328},"obj":"UMLS/C1323304"},{"id":"T2334","span":{"begin":214,"end":225},"obj":"UMLS/C1261381"},{"id":"T2333","span":{"begin":343,"end":354},"obj":"UMLS/C1527200"},{"id":"T2332","span":{"begin":307,"end":328},"obj":"UP/O77510"},{"id":"T2330","span":{"begin":229,"end":235},"obj":"UMLS/C0392905"},{"id":"T2329","span":{"begin":96,"end":101},"obj":"UMLS/C0392905"},{"id":"T2328","span":{"begin":307,"end":328},"obj":"UP/Q75N23"},{"id":"T2326","span":{"begin":229,"end":235},"obj":"UMLS/C1269611"},{"id":"T2325","span":{"begin":96,"end":101},"obj":"UMLS/C1269611"},{"id":"T2324","span":{"begin":293,"end":303},"obj":"UMLS/C0243077"},{"id":"T2297","span":{"begin":175,"end":180},"obj":"UMLS/C1269647"},{"id":"T2295","span":{"begin":485,"end":497},"obj":"UMLS/C1947919"},{"id":"T2286","span":{"begin":155,"end":163},"obj":"UMLS/C1283071"},{"id":"T2283","span":{"begin":473,"end":484},"obj":"UMLS/C0039796"},{"id":"T2282","span":{"begin":307,"end":328},"obj":"UMLS/C1522668"},{"id":"T2281","span":{"begin":362,"end":369},"obj":"UMLS/C1705535"},{"id":"T2533","span":{"begin":418,"end":421},"obj":"UMLS/C2348947"},{"id":"T2528","span":{"begin":79,"end":86},"obj":"UMLS/C0039194"},{"id":"T2509","span":{"begin":229,"end":235},"obj":"UMLS/C0022417"},{"id":"T2508","span":{"begin":96,"end":101},"obj":"UMLS/C0022417"},{"id":"T2505","span":{"begin":307,"end":328},"obj":"UP/P06804"},{"id":"T2499","span":{"begin":485,"end":497},"obj":"UMLS/C1547755"},{"id":"T2493","span":{"begin":307,"end":328},"obj":"UP/Q1WM27"},{"id":"T2272","span":{"begin":191,"end":193},"obj":"UMLS/C0319022"},{"id":"T2266","span":{"begin":46,"end":59},"obj":"UMLS/C0702249"},{"id":"T2265","span":{"begin":485,"end":497},"obj":"UMLS/C1533134"},{"id":"T2260","span":{"begin":395,"end":407},"obj":"UMLS/C0333348"},{"id":"T2258","span":{"begin":307,"end":328},"obj":"UP/P51742"},{"id":"T2252","span":{"begin":473,"end":484},"obj":"UMLS/C1547427"},{"id":"T2250","span":{"begin":46,"end":59},"obj":"UMLS/C1523986"},{"id":"T2249","span":{"begin":155,"end":163},"obj":"UMLS/C0391871"},{"id":"T2242","span":{"begin":408,"end":417},"obj":"UMLS/C0079189"},{"id":"T2241","span":{"begin":145,"end":154},"obj":"UMLS/C0079189"},{"id":"T2236","span":{"begin":307,"end":328},"obj":"UP/P48094"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"pmc-enju-pas","denotations":[{"id":"T2979","span":{"begin":499,"end":500},"obj":"-RRB-"},{"id":"T2978","span":{"begin":498,"end":499},"obj":"CD"},{"id":"T2977","span":{"begin":497,"end":498},"obj":"-LRB-"},{"id":"T2976","span":{"begin":484,"end":496},"obj":"NN"},{"id":"T2975","span":{"begin":472,"end":483},"obj":"JJ"},{"id":"T2974","span":{"begin":468,"end":471},"obj":"JJ"},{"id":"T2973","span":{"begin":465,"end":467},"obj":"IN"},{"id":"T2972","span":{"begin":453,"end":464},"obj":"NN"},{"id":"T2971","span":{"begin":449,"end":452},"obj":"DT"},{"id":"T2970","span":{"begin":446,"end":448},"obj":"IN"},{"id":"T2969","span":{"begin":440,"end":445},"obj":"NN"},{"id":"T2968","span":{"begin":430,"end":439},"obj":"JJ"},{"id":"T2967","span":{"begin":426,"end":429},"obj":"DT"},{"id":"T2966","span":{"begin":421,"end":425},"obj":"VB"},{"id":"T2965","span":{"begin":417,"end":420},"obj":"VB"},{"id":"T2964","span":{"begin":407,"end":416},"obj":"NN"},{"id":"T2963","span":{"begin":394,"end":406},"obj":"JJ"},{"id":"T2962","span":{"begin":390,"end":393},"obj":"JJ"},{"id":"T2961","span":{"begin":387,"end":389},"obj":"IN"},{"id":"T2960","span":{"begin":378,"end":386},"obj":"NN"},{"id":"T2959","span":{"begin":374,"end":377},"obj":"DT"},{"id":"T2958","span":{"begin":369,"end":373},"obj":"IN"},{"id":"T2957","span":{"begin":361,"end":368},"obj":"VB"},{"id":"T2956","span":{"begin":358,"end":360},"obj":"CD"},{"id":"T2955","span":{"begin":357,"end":358},"obj":"-RRB-"},{"id":"T2954","span":{"begin":355,"end":357},"obj":"NN"},{"id":"T2953","span":{"begin":354,"end":355},"obj":"-LRB-"},{"id":"T2952","span":{"begin":342,"end":353},"obj":"NN"},{"id":"T2951","span":{"begin":338,"end":341},"obj":"CC"},{"id":"T2950","span":{"begin":336,"end":337},"obj":"-RRB-"},{"id":"T2949","span":{"begin":334,"end":336},"obj":"NN"},{"id":"T2948","span":{"begin":333,"end":334},"obj":"-RRB-"},{"id":"T2947","span":{"begin":330,"end":333},"obj":"NN"},{"id":"T2946","span":{"begin":329,"end":330},"obj":"-LRB-"},{"id":"T2945","span":{"begin":322,"end":328},"obj":"NN"},{"id":"T2944","span":{"begin":313,"end":321},"obj":"NN"},{"id":"T2943","span":{"begin":307,"end":312},"obj":"NN"},{"id":"T2942","span":{"begin":304,"end":306},"obj":"IN"},{"id":"T2941","span":{"begin":293,"end":303},"obj":"NN"},{"id":"T2940","span":{"begin":288,"end":292},"obj":"IN"},{"id":"T2939","span":{"begin":279,"end":287},"obj":"VB"},{"id":"T2938","span":{"begin":270,"end":278},"obj":"NN"},{"id":"T2937","span":{"begin":261,"end":269},"obj":"JJ"},{"id":"T2936","span":{"begin":251,"end":260},"obj":"JJ"},{"id":"T2935","span":{"begin":247,"end":250},"obj":"DT"},{"id":"T2934","span":{"begin":244,"end":245},"obj":"-RRB-"},{"id":"T2933","span":{"begin":243,"end":244},"obj":"CD"},{"id":"T2932","span":{"begin":242,"end":243},"obj":"-LRB-"},{"id":"T2931","span":{"begin":239,"end":241},"obj":"NN"},{"id":"T2930","span":{"begin":236,"end":238},"obj":"IN"},{"id":"T2929","span":{"begin":229,"end":235},"obj":"NN"},{"id":"T2928","span":{"begin":226,"end":228},"obj":"IN"},{"id":"T2927","span":{"begin":214,"end":225},"obj":"NN"},{"id":"T2926","span":{"begin":210,"end":213},"obj":"DT"},{"id":"T2925","span":{"begin":207,"end":209},"obj":"IN"},{"id":"T2924","span":{"begin":197,"end":206},"obj":"JJ"},{"id":"T2923","span":{"begin":194,"end":196},"obj":"VB"},{"id":"T2922","span":{"begin":191,"end":193},"obj":"TO"},{"id":"T2921","span":{"begin":185,"end":190},"obj":"VB"},{"id":"T2920","span":{"begin":181,"end":184},"obj":"VB"},{"id":"T2919","span":{"begin":175,"end":180},"obj":"NN"},{"id":"T2918","span":{"begin":169,"end":174},"obj":"DT"},{"id":"T2917","span":{"begin":164,"end":168},"obj":"IN"},{"id":"T2916","span":{"begin":155,"end":163},"obj":"VB"},{"id":"T2915","span":{"begin":145,"end":154},"obj":"NN"},{"id":"T2914","span":{"begin":129,"end":144},"obj":"JJ"},{"id":"T2913","span":{"begin":116,"end":127},"obj":"NN"},{"id":"T2912","span":{"begin":107,"end":115},"obj":"JJ"},{"id":"T2911","span":{"begin":103,"end":106},"obj":"CC"},{"id":"T2910","span":{"begin":101,"end":102},"obj":"-COMMA-"},{"id":"T2909","span":{"begin":96,"end":101},"obj":"NN"},{"id":"T2908","span":{"begin":92,"end":95},"obj":"DT"},{"id":"T2907","span":{"begin":87,"end":91},"obj":"IN"},{"id":"T2906","span":{"begin":81,"end":86},"obj":"NN"},{"id":"T2905","span":{"begin":79,"end":80},"obj":"NN"},{"id":"T2904","span":{"begin":75,"end":78},"obj":"CC"},{"id":"T2903","span":{"begin":63,"end":74},"obj":"NN"},{"id":"T2902","span":{"begin":60,"end":62},"obj":"IN"},{"id":"T2901","span":{"begin":46,"end":59},"obj":"NN"},{"id":"T2900","span":{"begin":43,"end":45},"obj":"IN"},{"id":"T2899","span":{"begin":29,"end":42},"obj":"VB"},{"id":"T2898","span":{"begin":26,"end":28},"obj":"VB"},{"id":"T2897","span":{"begin":24,"end":25},"obj":"-RRB-"},{"id":"T2896","span":{"begin":22,"end":24},"obj":"NN"},{"id":"T2895","span":{"begin":21,"end":22},"obj":"-LRB-"},{"id":"T2894","span":{"begin":11,"end":20},"obj":"NN"},{"id":"T2893","span":{"begin":0,"end":10},"obj":"JJ"}],"relations":[{"id":"R1151","pred":"arg1Of","subj":"T2894","obj":"T2893"},{"id":"R1152","pred":"arg1Of","subj":"T2894","obj":"T2895"},{"id":"R1153","pred":"arg1Of","subj":"T2894","obj":"T2898"},{"id":"R1154","pred":"arg2Of","subj":"T2894","obj":"T2899"},{"id":"R1155","pred":"arg2Of","subj":"T2896","obj":"T2895"},{"id":"R1156","pred":"arg3Of","subj":"T2897","obj":"T2895"},{"id":"R1157","pred":"arg2Of","subj":"T2899","obj":"T2898"},{"id":"R1158","pred":"arg1Of","subj":"T2901","obj":"T2899"},{"id":"R1159","pred":"arg2Of","subj":"T2901","obj":"T2900"},{"id":"R1160","pred":"arg1Of","subj":"T2901","obj":"T2902"},{"id":"R1161","pred":"arg1Of","subj":"T2903","obj":"T2904"},{"id":"R1162","pred":"arg1Of","subj":"T2904","obj":"T2907"},{"id":"R1163","pred":"arg1Of","subj":"T2904","obj":"T2911"},{"id":"R1164","pred":"arg2Of","subj":"T2906","obj":"T2904"},{"id":"R1165","pred":"arg1Of","subj":"T2906","obj":"T2905"},{"id":"R1166","pred":"arg2Of","subj":"T2909","obj":"T2907"},{"id":"R1167","pred":"arg1Of","subj":"T2909","obj":"T2908"},{"id":"R1168","pred":"arg2Of","subj":"T2911","obj":"T2902"},{"id":"R1169","pred":"arg1Of","subj":"T2911","obj":"T2910"},{"id":"R1170","pred":"arg2Of","subj":"T2913","obj":"T2911"},{"id":"R1171","pred":"arg1Of","subj":"T2913","obj":"T2912"},{"id":"R1172","pred":"arg1Of","subj":"T2915","obj":"T2914"},{"id":"R1173","pred":"arg2Of","subj":"T2915","obj":"T2916"},{"id":"R1174","pred":"arg1Of","subj":"T2915","obj":"T2920"},{"id":"R1175","pred":"arg2Of","subj":"T2915","obj":"T2921"},{"id":"R1176","pred":"arg1Of","subj":"T2915","obj":"T2923"},{"id":"R1177","pred":"arg1Of","subj":"T2915","obj":"T2924"},{"id":"R1178","pred":"arg1Of","subj":"T2916","obj":"T2917"},{"id":"R1179","pred":"arg2Of","subj":"T2919","obj":"T2917"},{"id":"R1180","pred":"arg1Of","subj":"T2919","obj":"T2918"},{"id":"R1181","pred":"arg2Of","subj":"T2921","obj":"T2920"},{"id":"R1182","pred":"arg1Of","subj":"T2921","obj":"T2932"},{"id":"R1183","pred":"arg3Of","subj":"T2923","obj":"T2921"},{"id":"R1184","pred":"arg1Of","subj":"T2923","obj":"T2922"},{"id":"R1185","pred":"arg2Of","subj":"T2924","obj":"T2923"},{"id":"R1186","pred":"arg1Of","subj":"T2924","obj":"T2925"},{"id":"R1187","pred":"arg2Of","subj":"T2927","obj":"T2925"},{"id":"R1188","pred":"arg1Of","subj":"T2927","obj":"T2926"},{"id":"R1189","pred":"arg1Of","subj":"T2927","obj":"T2928"},{"id":"R1190","pred":"arg1Of","subj":"T2927","obj":"T2930"},{"id":"R1191","pred":"arg2Of","subj":"T2929","obj":"T2928"},{"id":"R1192","pred":"arg2Of","subj":"T2931","obj":"T2930"},{"id":"R1193","pred":"arg2Of","subj":"T2933","obj":"T2932"},{"id":"R1194","pred":"arg3Of","subj":"T2934","obj":"T2932"},{"id":"R1195","pred":"arg1Of","subj":"T2938","obj":"T2935"},{"id":"R1196","pred":"arg1Of","subj":"T2938","obj":"T2936"},{"id":"R1197","pred":"arg1Of","subj":"T2938","obj":"T2937"},{"id":"R1198","pred":"arg2Of","subj":"T2938","obj":"T2939"},{"id":"R1199","pred":"arg1Of","subj":"T2938","obj":"T2950"},{"id":"R1200","pred":"arg1Of","subj":"T2938","obj":"T2951"},{"id":"R1201","pred":"arg1Of","subj":"T2939","obj":"T2940"},{"id":"R1202","pred":"arg2Of","subj":"T2941","obj":"T2940"},{"id":"R1203","pred":"arg1Of","subj":"T2941","obj":"T2942"},{"id":"R1204","pred":"arg1Of","subj":"T2945","obj":"T2943"},{"id":"R1205","pred":"arg1Of","subj":"T2945","obj":"T2944"},{"id":"R1206","pred":"arg1Of","subj":"T2945","obj":"T2946"},{"id":"R1207","pred":"arg2Of","subj":"T2947","obj":"T2946"},{"id":"R1208","pred":"arg3Of","subj":"T2948","obj":"T2946"},{"id":"R1209","pred":"arg2Of","subj":"T2949","obj":"T2942"},{"id":"R1210","pred":"arg1Of","subj":"T2949","obj":"T2945"},{"id":"R1211","pred":"arg1Of","subj":"T2951","obj":"T2957"},{"id":"R1212","pred":"arg2Of","subj":"T2952","obj":"T2951"},{"id":"R1213","pred":"arg1Of","subj":"T2952","obj":"T2953"},{"id":"R1214","pred":"arg1Of","subj":"T2952","obj":"T2956"},{"id":"R1215","pred":"arg2Of","subj":"T2954","obj":"T2953"},{"id":"R1216","pred":"arg3Of","subj":"T2955","obj":"T2953"},{"id":"R1217","pred":"arg1Of","subj":"T2960","obj":"T2959"},{"id":"R1218","pred":"arg1Of","subj":"T2960","obj":"T2961"},{"id":"R1219","pred":"arg1Of","subj":"T2960","obj":"T2965"},{"id":"R1220","pred":"arg1Of","subj":"T2960","obj":"T2966"},{"id":"R1221","pred":"arg2Of","subj":"T2964","obj":"T2961"},{"id":"R1222","pred":"arg1Of","subj":"T2964","obj":"T2962"},{"id":"R1223","pred":"arg1Of","subj":"T2964","obj":"T2963"},{"id":"R1224","pred":"arg2Of","subj":"T2966","obj":"T2957"},{"id":"R1225","pred":"arg1Of","subj":"T2966","obj":"T2958"},{"id":"R1226","pred":"arg2Of","subj":"T2966","obj":"T2965"},{"id":"R1227","pred":"arg1Of","subj":"T2966","obj":"T2970"},{"id":"R1228","pred":"arg1Of","subj":"T2966","obj":"T2977"},{"id":"R1229","pred":"arg2Of","subj":"T2969","obj":"T2966"},{"id":"R1230","pred":"arg1Of","subj":"T2969","obj":"T2967"},{"id":"R1231","pred":"arg1Of","subj":"T2969","obj":"T2968"},{"id":"R1232","pred":"arg2Of","subj":"T2972","obj":"T2970"},{"id":"R1233","pred":"arg1Of","subj":"T2972","obj":"T2971"},{"id":"R1234","pred":"arg1Of","subj":"T2972","obj":"T2973"},{"id":"R1235","pred":"arg2Of","subj":"T2976","obj":"T2973"},{"id":"R1236","pred":"arg1Of","subj":"T2976","obj":"T2974"},{"id":"R1237","pred":"arg1Of","subj":"T2976","obj":"T2975"},{"id":"R1238","pred":"arg2Of","subj":"T2978","obj":"T2977"},{"id":"R1239","pred":"arg3Of","subj":"T2979","obj":"T2977"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"bionlp-st-ge-2016-coref","denotations":[{"id":"T3464","span":{"begin":342,"end":360},"obj":"Antecedent"},{"id":"T3463","span":{"begin":307,"end":336},"obj":"Antecedent"},{"id":"T3462","span":{"begin":390,"end":416},"obj":"Anaphor"}],"relations":[{"id":"R1726","pred":"boundBy","subj":"T3462","obj":"T3463"},{"id":"R1728","pred":"boundBy","subj":"T3462","obj":"T3464"}],"namespaces":[{"prefix":"_base","uri":"https://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T3483","span":{"begin":342,"end":360},"obj":"Protein"},{"id":"T3482","span":{"begin":307,"end":336},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T3688","span":{"begin":330,"end":336},"obj":"http://www.uniprot.org/uniprot/P01375"},{"id":"T3686","span":{"begin":330,"end":333},"obj":"http://www.uniprot.org/uniprot/P01375"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"GO-BP","denotations":[{"id":"T2770","span":{"begin":453,"end":464},"obj":"http://purl.obolibrary.org/obo/GO_0032502"},{"id":"T2769","span":{"begin":313,"end":321},"obj":"http://purl.obolibrary.org/obo/GO_0070265"},{"id":"T2768","span":{"begin":313,"end":321},"obj":"http://purl.obolibrary.org/obo/GO_0019835"},{"id":"T2767","span":{"begin":313,"end":321},"obj":"http://purl.obolibrary.org/obo/GO_0008219"},{"id":"T2766","span":{"begin":313,"end":321},"obj":"http://purl.obolibrary.org/obo/GO_0001906"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"GO-MF","denotations":[{"id":"T3515","span":{"begin":355,"end":360},"obj":"http://purl.obolibrary.org/obo/GO_0005149"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"GO-CC","denotations":[{"id":"T3553","span":{"begin":175,"end":180},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T3552","span":{"begin":81,"end":86},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"sentences","denotations":[{"id":"T2750","span":{"begin":247,"end":501},"obj":"Sentence"},{"id":"T2749","span":{"begin":129,"end":246},"obj":"Sentence"},{"id":"T2748","span":{"begin":0,"end":128},"obj":"Sentence"},{"id":"T18","span":{"begin":0,"end":128},"obj":"Sentence"},{"id":"T19","span":{"begin":129,"end":246},"obj":"Sentence"},{"id":"T20","span":{"begin":247,"end":501},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"ICD10","denotations":[{"id":"T3567","span":{"begin":11,"end":20},"obj":"http://purl.bioontology.org/ontology/ICD10/M13.9"},{"id":"T3566","span":{"begin":0,"end":20},"obj":"http://purl.bioontology.org/ontology/ICD10/M06.9"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"simple1","denotations":[{"id":"T3654","span":{"begin":342,"end":360},"obj":"Protein"},{"id":"T3653","span":{"begin":307,"end":336},"obj":"Protein"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"DLUT931","denotations":[{"id":"T3795","span":{"begin":293,"end":303},"obj":"Negative_regulation"},{"id":"T3763","span":{"begin":342,"end":360},"obj":"Protein"},{"id":"T3762","span":{"begin":307,"end":336},"obj":"Protein"}],"relations":[{"id":"R1780","pred":"themeOf","subj":"T3762","obj":"T3795"},{"id":"R1782","pred":"themeOf","subj":"T3763","obj":"T3795"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T4592","span":{"begin":145,"end":180},"obj":"Regulation"},{"id":"T4582","span":{"begin":79,"end":86},"obj":"Entity"},{"id":"T4581","span":{"begin":293,"end":336},"obj":"Entity"},{"id":"T4567","span":{"begin":307,"end":336},"obj":"Protein"},{"id":"T4558","span":{"begin":394,"end":416},"obj":"Protein"},{"id":"T4551","span":{"begin":63,"end":74},"obj":"Entity"},{"id":"T4537","span":{"begin":169,"end":180},"obj":"Entity"},{"id":"T4527","span":{"begin":145,"end":180},"obj":"Protein"},{"id":"T4525","span":{"begin":342,"end":360},"obj":"Protein"},{"id":"T4521","span":{"begin":239,"end":241},"obj":"Protein"},{"id":"T4518","span":{"begin":22,"end":24},"obj":"Protein"}],"relations":[{"id":"R2455","pred":"themeOf","subj":"T4527","obj":"T4592"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T3942","span":{"begin":500,"end":501},"obj":"."},{"id":"T3941","span":{"begin":499,"end":500},"obj":"NN"},{"id":"T3940","span":{"begin":498,"end":499},"obj":"CD"},{"id":"T3939","span":{"begin":497,"end":498},"obj":"JJ"},{"id":"T3938","span":{"begin":484,"end":496},"obj":"NNS"},{"id":"T3937","span":{"begin":472,"end":483},"obj":"JJ"},{"id":"T3936","span":{"begin":468,"end":471},"obj":"JJ"},{"id":"T3935","span":{"begin":465,"end":467},"obj":"IN"},{"id":"T3934","span":{"begin":453,"end":464},"obj":"NN"},{"id":"T3933","span":{"begin":449,"end":452},"obj":"DT"},{"id":"T3932","span":{"begin":446,"end":448},"obj":"IN"},{"id":"T3931","span":{"begin":440,"end":445},"obj":"NN"},{"id":"T3930","span":{"begin":430,"end":439},"obj":"JJ"},{"id":"T3929","span":{"begin":426,"end":429},"obj":"DT"},{"id":"T3928","span":{"begin":421,"end":425},"obj":"VBN"},{"id":"T3927","span":{"begin":417,"end":420},"obj":"VBZ"},{"id":"T3926","span":{"begin":407,"end":416},"obj":"NNS"},{"id":"T3925","span":{"begin":394,"end":406},"obj":"JJ"},{"id":"T3924","span":{"begin":390,"end":393},"obj":"JJ"},{"id":"T3923","span":{"begin":387,"end":389},"obj":"IN"},{"id":"T3922","span":{"begin":378,"end":386},"obj":"NN"},{"id":"T3921","span":{"begin":374,"end":377},"obj":"DT"},{"id":"T3920","span":{"begin":369,"end":373},"obj":"IN"},{"id":"T3919","span":{"begin":361,"end":368},"obj":"VBP"},{"id":"T3918","span":{"begin":358,"end":360},"obj":"CD"},{"id":"T3917","span":{"begin":357,"end":358},"obj":"-RRB-"},{"id":"T3916","span":{"begin":355,"end":357},"obj":"NNP"},{"id":"T3915","span":{"begin":354,"end":355},"obj":"-LRB-"},{"id":"T3914","span":{"begin":342,"end":353},"obj":"NN"},{"id":"T3913","span":{"begin":338,"end":341},"obj":"CC"},{"id":"T3912","span":{"begin":336,"end":337},"obj":"-RRB-"},{"id":"T3911","span":{"begin":335,"end":336},"obj":"VBN"},{"id":"T3910","span":{"begin":334,"end":335},"obj":":"},{"id":"T3909","span":{"begin":333,"end":334},"obj":"-RRB-"},{"id":"T3908","span":{"begin":330,"end":333},"obj":"NNP"},{"id":"T3907","span":{"begin":329,"end":330},"obj":"-LRB-"},{"id":"T3906","span":{"begin":322,"end":328},"obj":"NN"},{"id":"T3905","span":{"begin":313,"end":321},"obj":"NN"},{"id":"T3904","span":{"begin":307,"end":312},"obj":"NN"},{"id":"T3903","span":{"begin":304,"end":306},"obj":"IN"},{"id":"T3902","span":{"begin":293,"end":303},"obj":"NNS"},{"id":"T3901","span":{"begin":288,"end":292},"obj":"IN"},{"id":"T3900","span":{"begin":279,"end":287},"obj":"VBN"},{"id":"T3899","span":{"begin":270,"end":278},"obj":"NNS"},{"id":"T3898","span":{"begin":261,"end":269},"obj":"JJ"},{"id":"T3897","span":{"begin":251,"end":260},"obj":"JJ"},{"id":"T3896","span":{"begin":247,"end":250},"obj":"DT"},{"id":"T3895","span":{"begin":245,"end":246},"obj":"."},{"id":"T3894","span":{"begin":244,"end":245},"obj":"NNP"},{"id":"T3893","span":{"begin":243,"end":244},"obj":"CD"},{"id":"T3892","span":{"begin":242,"end":243},"obj":"NNP"},{"id":"T3891","span":{"begin":239,"end":241},"obj":"NNP"},{"id":"T3890","span":{"begin":236,"end":238},"obj":"IN"},{"id":"T3889","span":{"begin":229,"end":235},"obj":"NNS"},{"id":"T3888","span":{"begin":226,"end":228},"obj":"IN"},{"id":"T3887","span":{"begin":214,"end":225},"obj":"NN"},{"id":"T3886","span":{"begin":210,"end":213},"obj":"DT"},{"id":"T3885","span":{"begin":207,"end":209},"obj":"IN"},{"id":"T3884","span":{"begin":197,"end":206},"obj":"JJ"},{"id":"T3883","span":{"begin":194,"end":196},"obj":"VB"},{"id":"T3882","span":{"begin":191,"end":193},"obj":"TO"},{"id":"T3881","span":{"begin":185,"end":190},"obj":"VBN"},{"id":"T3880","span":{"begin":181,"end":184},"obj":"VBP"},{"id":"T3879","span":{"begin":175,"end":180},"obj":"NNS"},{"id":"T3878","span":{"begin":169,"end":174},"obj":"DT"},{"id":"T3877","span":{"begin":164,"end":168},"obj":"IN"},{"id":"T3876","span":{"begin":155,"end":163},"obj":"VBN"},{"id":"T3875","span":{"begin":145,"end":154},"obj":"NNS"},{"id":"T3874","span":{"begin":129,"end":144},"obj":"JJ"},{"id":"T3873","span":{"begin":127,"end":128},"obj":"."},{"id":"T3872","span":{"begin":116,"end":127},"obj":"NN"},{"id":"T3871","span":{"begin":107,"end":115},"obj":"JJ"},{"id":"T3870","span":{"begin":103,"end":106},"obj":"CC"},{"id":"T3869","span":{"begin":101,"end":102},"obj":","},{"id":"T3868","span":{"begin":96,"end":101},"obj":"JJ"},{"id":"T3867","span":{"begin":92,"end":95},"obj":"DT"},{"id":"T3866","span":{"begin":87,"end":91},"obj":"IN"},{"id":"T3865","span":{"begin":81,"end":86},"obj":"NNS"},{"id":"T3864","span":{"begin":79,"end":80},"obj":"NNP"},{"id":"T3863","span":{"begin":75,"end":78},"obj":"CC"},{"id":"T3862","span":{"begin":63,"end":74},"obj":"NNS"},{"id":"T3861","span":{"begin":60,"end":62},"obj":"IN"},{"id":"T3860","span":{"begin":46,"end":59},"obj":"NNS"},{"id":"T3859","span":{"begin":43,"end":45},"obj":"IN"},{"id":"T3858","span":{"begin":29,"end":42},"obj":"VBN"},{"id":"T3857","span":{"begin":26,"end":28},"obj":"VBZ"},{"id":"T3856","span":{"begin":24,"end":25},"obj":"-RRB-"},{"id":"T3855","span":{"begin":22,"end":24},"obj":"NNP"},{"id":"T3854","span":{"begin":21,"end":22},"obj":"-LRB-"},{"id":"T3853","span":{"begin":11,"end":20},"obj":"NNS"},{"id":"T3852","span":{"begin":0,"end":10},"obj":"JJ"}],"relations":[{"id":"R1821","pred":"amod","subj":"T3852","obj":"T3853"},{"id":"R1822","pred":"nsubjpass","subj":"T3853","obj":"T3858"},{"id":"R1823","pred":"punct","subj":"T3854","obj":"T3853"},{"id":"R1824","pred":"appos","subj":"T3855","obj":"T3853"},{"id":"R1828","pred":"punct","subj":"T3856","obj":"T3853"},{"id":"R1829","pred":"auxpass","subj":"T3857","obj":"T3858"},{"id":"R1832","pred":"ROOT","subj":"T3858","obj":"T3858"},{"id":"R1833","pred":"agent","subj":"T3859","obj":"T3858"},{"id":"R1836","pred":"pobj","subj":"T3860","obj":"T3859"},{"id":"R1838","pred":"prep","subj":"T3861","obj":"T3860"},{"id":"R1841","pred":"pobj","subj":"T3862","obj":"T3861"},{"id":"R1843","pred":"cc","subj":"T3863","obj":"T3862"},{"id":"R1845","pred":"compound","subj":"T3864","obj":"T3865"},{"id":"R1846","pred":"conj","subj":"T3865","obj":"T3862"},{"id":"R1847","pred":"prep","subj":"T3866","obj":"T3858"},{"id":"R1848","pred":"det","subj":"T3867","obj":"T3868"},{"id":"R1849","pred":"amod","subj":"T3868","obj":"T3872"},{"id":"R1850","pred":"punct","subj":"T3869","obj":"T3868"},{"id":"R1852","pred":"cc","subj":"T3870","obj":"T3868"},{"id":"R1855","pred":"conj","subj":"T3871","obj":"T3868"},{"id":"R1858","pred":"pobj","subj":"T3872","obj":"T3866"},{"id":"R1861","pred":"punct","subj":"T3873","obj":"T3858"},{"id":"R1865","pred":"amod","subj":"T3874","obj":"T3875"},{"id":"R1869","pred":"nsubjpass","subj":"T3875","obj":"T3881"},{"id":"R1873","pred":"acl","subj":"T3876","obj":"T3875"},{"id":"R1878","pred":"prep","subj":"T3877","obj":"T3876"},{"id":"R1880","pred":"det","subj":"T3878","obj":"T3879"},{"id":"R1883","pred":"pobj","subj":"T3879","obj":"T3877"},{"id":"R1887","pred":"auxpass","subj":"T3880","obj":"T3881"},{"id":"R1891","pred":"ROOT","subj":"T3881","obj":"T3881"},{"id":"R1894","pred":"aux","subj":"T3882","obj":"T3883"},{"id":"R1898","pred":"xcomp","subj":"T3883","obj":"T3881"},{"id":"R1901","pred":"acomp","subj":"T3884","obj":"T3883"},{"id":"R1905","pred":"prep","subj":"T3885","obj":"T3883"},{"id":"R1909","pred":"det","subj":"T3886","obj":"T3887"},{"id":"R1913","pred":"pobj","subj":"T3887","obj":"T3885"},{"id":"R1918","pred":"prep","subj":"T3888","obj":"T3887"},{"id":"R1922","pred":"pobj","subj":"T3889","obj":"T3888"},{"id":"R1923","pred":"prep","subj":"T3890","obj":"T3887"},{"id":"R1925","pred":"compound","subj":"T3891","obj":"T3892"},{"id":"R1929","pred":"pobj","subj":"T3892","obj":"T3890"},{"id":"R1934","pred":"nummod","subj":"T3893","obj":"T3894"},{"id":"R1939","pred":"appos","subj":"T3894","obj":"T3892"},{"id":"R1942","pred":"punct","subj":"T3895","obj":"T3881"},{"id":"R1947","pred":"det","subj":"T3896","obj":"T3899"},{"id":"R1951","pred":"amod","subj":"T3897","obj":"T3899"},{"id":"R1955","pred":"amod","subj":"T3898","obj":"T3899"},{"id":"R1958","pred":"nsubj","subj":"T3899","obj":"T3911"},{"id":"R1962","pred":"acl","subj":"T3900","obj":"T3899"},{"id":"R1966","pred":"prep","subj":"T3901","obj":"T3900"},{"id":"R1969","pred":"pobj","subj":"T3902","obj":"T3901"},{"id":"R1973","pred":"prep","subj":"T3903","obj":"T3902"},{"id":"R1977","pred":"compound","subj":"T3904","obj":"T3905"},{"id":"R1983","pred":"compound","subj":"T3905","obj":"T3906"},{"id":"R1984","pred":"pobj","subj":"T3906","obj":"T3903"},{"id":"R1985","pred":"punct","subj":"T3907","obj":"T3908"},{"id":"R1988","pred":"appos","subj":"T3908","obj":"T3906"},{"id":"R1990","pred":"punct","subj":"T3909","obj":"T3900"},{"id":"R1993","pred":"punct","subj":"T3910","obj":"T3899"},{"id":"R1997","pred":"ROOT","subj":"T3911","obj":"T3911"},{"id":"R2000","pred":"punct","subj":"T3912","obj":"T3911"},{"id":"R2004","pred":"cc","subj":"T3913","obj":"T3911"},{"id":"R2008","pred":"nsubj","subj":"T3914","obj":"T3919"},{"id":"R2012","pred":"punct","subj":"T3915","obj":"T3916"},{"id":"R2015","pred":"appos","subj":"T3916","obj":"T3914"},{"id":"R2019","pred":"punct","subj":"T3917","obj":"T3918"},{"id":"R2023","pred":"nsubj","subj":"T3918","obj":"T3919"},{"id":"R2026","pred":"conj","subj":"T3919","obj":"T3911"},{"id":"R2033","pred":"mark","subj":"T3920","obj":"T3928"},{"id":"R2037","pred":"det","subj":"T3921","obj":"T3922"},{"id":"R2041","pred":"nsubj","subj":"T3922","obj":"T3928"},{"id":"R2045","pred":"prep","subj":"T3923","obj":"T3922"},{"id":"R2048","pred":"amod","subj":"T3924","obj":"T3926"},{"id":"R2052","pred":"amod","subj":"T3925","obj":"T3926"},{"id":"R2056","pred":"pobj","subj":"T3926","obj":"T3923"},{"id":"R2060","pred":"aux","subj":"T3927","obj":"T3928"},{"id":"R2064","pred":"ccomp","subj":"T3928","obj":"T3919"},{"id":"R2068","pred":"det","subj":"T3929","obj":"T3931"},{"id":"R2071","pred":"amod","subj":"T3930","obj":"T3931"},{"id":"R2075","pred":"attr","subj":"T3931","obj":"T3928"},{"id":"R2079","pred":"prep","subj":"T3932","obj":"T3931"},{"id":"R2081","pred":"det","subj":"T3933","obj":"T3934"},{"id":"R2084","pred":"pobj","subj":"T3934","obj":"T3932"},{"id":"R2087","pred":"prep","subj":"T3935","obj":"T3934"},{"id":"R2091","pred":"amod","subj":"T3936","obj":"T3938"},{"id":"R2095","pred":"amod","subj":"T3937","obj":"T3938"},{"id":"R2097","pred":"pobj","subj":"T3938","obj":"T3935"},{"id":"R2100","pred":"amod","subj":"T3939","obj":"T3941"},{"id":"R2104","pred":"nummod","subj":"T3940","obj":"T3941"},{"id":"R2107","pred":"conj","subj":"T3941","obj":"T3931"},{"id":"R2111","pred":"punct","subj":"T3942","obj":"T3919"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T3604","span":{"begin":293,"end":303},"obj":"Negative_regulation"},{"id":"T3603","span":{"begin":293,"end":303},"obj":"Negative_regulation"},{"id":"T3602","span":{"begin":342,"end":360},"obj":"Protein"},{"id":"T3601","span":{"begin":307,"end":336},"obj":"Protein"}],"relations":[{"id":"R1751","pred":"themeOf","subj":"T3601","obj":"T3603"},{"id":"R1753","pred":"themeOf","subj":"T3602","obj":"T3604"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}

{"project":"testone","denotations":[{"id":"T2108","span":{"begin":342,"end":360},"obj":"Protein"},{"id":"T2107","span":{"begin":307,"end":336},"obj":"Protein"}],"text":"Rheumatoid arthritis (RA) is characterized by infiltrations of macrophages and T cells into the joint, and synovial hyperplasia. Proinflammatory cytokines released from these cells are known to be important in the destruction of joints in RA [1]. The favorable clinical benefits obtained with inhibitors of tumor necrosis factor (TNF)-α) and interleukin (IL)-1 suggest that the blockade of key inflammatory cytokines has been the important issue in the development of new therapeutic applications [2]."}