PMC:1064895 / 17993-18390 JSONTXT

{"project":"test3","denotations":[{"id":"T13348","span":{"begin":210,"end":220},"obj":"Gene_expression"},{"id":"T13347","span":{"begin":204,"end":209},"obj":"Protein"},{"id":"T13346","span":{"begin":196,"end":203},"obj":"Positive_regulation"},{"id":"T13345","span":{"begin":175,"end":183},"obj":"Negative_regulation"},{"id":"T13344","span":{"begin":36,"end":46},"obj":"Gene_expression"},{"id":"T13343","span":{"begin":30,"end":35},"obj":"Protein"},{"id":"T13342","span":{"begin":20,"end":29},"obj":"Positive_regulation"},{"id":"T13332","span":{"begin":204,"end":209},"obj":"Protein"},{"id":"T13331","span":{"begin":30,"end":35},"obj":"Protein"}],"relations":[{"id":"R7273","pred":"themeOf","subj":"T13343","obj":"T13344"},{"id":"R7274","pred":"themeOf","subj":"T13344","obj":"T13342"},{"id":"R7275","pred":"themeOf","subj":"T13346","obj":"T13345"},{"id":"R7276","pred":"themeOf","subj":"T13347","obj":"T13348"},{"id":"R7277","pred":"themeOf","subj":"T13348","obj":"T13346"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"BioNLP16_Messiy","denotations":[{"id":"T13963","span":{"begin":210,"end":220},"obj":"Gene_expression"},{"id":"T13962","span":{"begin":175,"end":183},"obj":"Negative_regulation"},{"id":"T13961","span":{"begin":187,"end":203},"obj":"Positive_regulation"},{"id":"T13960","span":{"begin":20,"end":29},"obj":"Positive_regulation"},{"id":"T13959","span":{"begin":36,"end":46},"obj":"Gene_expression"},{"id":"T13950","span":{"begin":204,"end":209},"obj":"Protein"},{"id":"T13949","span":{"begin":30,"end":35},"obj":"Protein"}],"relations":[{"id":"R7590","pred":"themeOf","subj":"T13949","obj":"T13959"},{"id":"R7591","pred":"themeOf","subj":"T13950","obj":"T13963"},{"id":"R7599","pred":"themeOf","subj":"T13959","obj":"T13960"},{"id":"R7600","pred":"themeOf","subj":"T13963","obj":"T13962"},{"id":"R7601","pred":"themeOf","subj":"T13963","obj":"T13961"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"BioNLP16_DUT","denotations":[{"id":"T14385","span":{"begin":210,"end":220},"obj":"Gene_expression"},{"id":"T14384","span":{"begin":187,"end":203},"obj":"Positive_regulation"},{"id":"T14383","span":{"begin":175,"end":183},"obj":"Negative_regulation"},{"id":"T14382","span":{"begin":36,"end":46},"obj":"Gene_expression"},{"id":"T14381","span":{"begin":20,"end":29},"obj":"Positive_regulation"},{"id":"T14372","span":{"begin":204,"end":209},"obj":"Protein"},{"id":"T14371","span":{"begin":30,"end":35},"obj":"Protein"}],"relations":[{"id":"R7938","pred":"themeOf","subj":"T14371","obj":"T14382"},{"id":"R7939","pred":"themeOf","subj":"T14372","obj":"T14385"},{"id":"R7947","pred":"themeOf","subj":"T14382","obj":"T14381"},{"id":"R7948","pred":"themeOf","subj":"T14385","obj":"T14383"},{"id":"R7949","pred":"themeOf","subj":"T14385","obj":"T14384"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"biosemtest","denotations":[{"id":"T13519","span":{"begin":204,"end":220},"obj":"UMLS/C1819444"},{"id":"T13518","span":{"begin":30,"end":46},"obj":"UMLS/C1819444"},{"id":"T13511","span":{"begin":79,"end":83},"obj":"UMLS/C0205309"},{"id":"T13510","span":{"begin":163,"end":174},"obj":"UMLS/C1546944"},{"id":"T13493","span":{"begin":264,"end":273},"obj":"UMLS/C1999216"},{"id":"T13486","span":{"begin":196,"end":203},"obj":"UMLS/C0205263"},{"id":"T13485","span":{"begin":284,"end":297},"obj":"UMLS/C0011777"},{"id":"T13473","span":{"begin":175,"end":183},"obj":"UMLS/C0547047"},{"id":"T13458","span":{"begin":175,"end":183},"obj":"UMLS/C0205216"},{"id":"T13457","span":{"begin":20,"end":29},"obj":"UMLS/C0205217"},{"id":"T13452","span":{"begin":275,"end":279},"obj":"UMLS/C0084183"},{"id":"T13448","span":{"begin":53,"end":57},"obj":"UMLS/C1321301"},{"id":"T13445","span":{"begin":124,"end":132},"obj":"UMLS/C1314939"},{"id":"T13434","span":{"begin":264,"end":273},"obj":"UMLS/C0243077"},{"id":"T13429","span":{"begin":90,"end":118},"obj":"UMLS/C0086982"},{"id":"T13424","span":{"begin":124,"end":132},"obj":"UMLS/C1947935"},{"id":"T13414","span":{"begin":225,"end":233},"obj":"UMLS/C1441672"},{"id":"T13413","span":{"begin":7,"end":15},"obj":"UMLS/C1441672"},{"id":"T13408","span":{"begin":326,"end":331},"obj":"UMLS/C0439044"},{"id":"T13407","span":{"begin":175,"end":183},"obj":"UMLS/C0392756"},{"id":"T13393","span":{"begin":76,"end":78},"obj":"UMLS/C0319022"},{"id":"T13390","span":{"begin":370,"end":375},"obj":"UMLS/C0439297"},{"id":"T13387","span":{"begin":152,"end":155},"obj":"UMLS/C0349966"},{"id":"T13385","span":{"begin":175,"end":183},"obj":"UMLS/C0442797"},{"id":"T13383","span":{"begin":20,"end":29},"obj":"UMLS/C0442805"},{"id":"T13381","span":{"begin":20,"end":29},"obj":"UMLS/C0442808"},{"id":"T13377","span":{"begin":163,"end":174},"obj":"UMLS/C0750502"},{"id":"T13370","span":{"begin":301,"end":311},"obj":"UMLS/C1707455"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"pmc-enju-pas","denotations":[{"id":"T13622","span":{"begin":76,"end":78},"obj":"TO"},{"id":"T13621","span":{"begin":66,"end":75},"obj":"JJ"},{"id":"T13620","span":{"begin":62,"end":65},"obj":"VB"},{"id":"T13619","span":{"begin":59,"end":61},"obj":"PRP"},{"id":"T13618","span":{"begin":57,"end":58},"obj":"-COMMA-"},{"id":"T13617","span":{"begin":53,"end":57},"obj":"NN"},{"id":"T13616","span":{"begin":50,"end":52},"obj":"NN"},{"id":"T13615","span":{"begin":47,"end":49},"obj":"IN"},{"id":"T13614","span":{"begin":36,"end":46},"obj":"NN"},{"id":"T13613","span":{"begin":30,"end":35},"obj":"NN"},{"id":"T13612","span":{"begin":20,"end":29},"obj":"VB"},{"id":"T13611","span":{"begin":16,"end":19},"obj":"DT"},{"id":"T13610","span":{"begin":7,"end":15},"obj":"VB"},{"id":"T13609","span":{"begin":0,"end":6},"obj":"VB"},{"id":"T13678","span":{"begin":395,"end":396},"obj":"-RRB-"},{"id":"T13677","span":{"begin":391,"end":395},"obj":"CD"},{"id":"T13676","span":{"begin":389,"end":390},"obj":"SYM"},{"id":"T13675","span":{"begin":387,"end":388},"obj":"NN"},{"id":"T13674","span":{"begin":385,"end":386},"obj":"-COLON-"},{"id":"T13673","span":{"begin":373,"end":385},"obj":"RB"},{"id":"T13672","span":{"begin":371,"end":372},"obj":"-COMMA-"},{"id":"T13671","span":{"begin":366,"end":371},"obj":"NN"},{"id":"T13670","span":{"begin":363,"end":365},"obj":"CD"},{"id":"T13669","span":{"begin":361,"end":362},"obj":"SYM"},{"id":"T13668","span":{"begin":358,"end":360},"obj":"CD"},{"id":"T13667","span":{"begin":351,"end":357},"obj":"IN"},{"id":"T13666","span":{"begin":348,"end":350},"obj":"CD"},{"id":"T13665","span":{"begin":346,"end":347},"obj":"CC"},{"id":"T13664","span":{"begin":343,"end":345},"obj":"CD"},{"id":"T13663","span":{"begin":339,"end":342},"obj":"CC"},{"id":"T13662","span":{"begin":337,"end":338},"obj":"CD"},{"id":"T13661","span":{"begin":335,"end":336},"obj":"CC"},{"id":"T13660","span":{"begin":332,"end":334},"obj":"CD"},{"id":"T13659","span":{"begin":331,"end":332},"obj":"-LRB-"},{"id":"T13658","span":{"begin":325,"end":330},"obj":"RB"},{"id":"T13657","span":{"begin":316,"end":324},"obj":"NN"},{"id":"T13656","span":{"begin":311,"end":315},"obj":"IN"},{"id":"T13655","span":{"begin":300,"end":310},"obj":"NN"},{"id":"T13654","span":{"begin":297,"end":299},"obj":"IN"},{"id":"T13653","span":{"begin":283,"end":296},"obj":"NN"},{"id":"T13652","span":{"begin":279,"end":282},"obj":"CC"},{"id":"T13651","span":{"begin":274,"end":278},"obj":"NN"},{"id":"T13650","span":{"begin":272,"end":273},"obj":"-COMMA-"},{"id":"T13649","span":{"begin":263,"end":272},"obj":"NN"},{"id":"T13648","span":{"begin":257,"end":262},"obj":"NN"},{"id":"T13647","span":{"begin":252,"end":256},"obj":"IN"},{"id":"T13646","span":{"begin":239,"end":251},"obj":"VB"},{"id":"T13645","span":{"begin":234,"end":238},"obj":"WRB"},{"id":"T13644","span":{"begin":225,"end":233},"obj":"VB"},{"id":"T13643","span":{"begin":221,"end":224},"obj":"VB"},{"id":"T13642","span":{"begin":210,"end":220},"obj":"NN"},{"id":"T13641","span":{"begin":204,"end":209},"obj":"NN"},{"id":"T13640","span":{"begin":187,"end":203},"obj":"JJ"},{"id":"T13639","span":{"begin":184,"end":186},"obj":"IN"},{"id":"T13638","span":{"begin":175,"end":183},"obj":"NN"},{"id":"T13637","span":{"begin":163,"end":174},"obj":"JJ"},{"id":"T13636","span":{"begin":160,"end":162},"obj":"DT"},{"id":"T13635","span":{"begin":158,"end":159},"obj":"-COMMA-"},{"id":"T13634","span":{"begin":157,"end":158},"obj":"CD"},{"id":"T13633","span":{"begin":152,"end":156},"obj":"NNP"},{"id":"T13632","span":{"begin":149,"end":151},"obj":"IN"},{"id":"T13631","span":{"begin":137,"end":148},"obj":"VB"},{"id":"T13630","span":{"begin":134,"end":136},"obj":"IN"},{"id":"T13629","span":{"begin":124,"end":132},"obj":"VB"},{"id":"T13628","span":{"begin":119,"end":123},"obj":"VB"},{"id":"T13627","span":{"begin":110,"end":118},"obj":"NN"},{"id":"T13626","span":{"begin":97,"end":109},"obj":"NN"},{"id":"T13625","span":{"begin":90,"end":96},"obj":"NN"},{"id":"T13624","span":{"begin":84,"end":89},"obj":"WDT"},{"id":"T13623","span":{"begin":79,"end":83},"obj":"VB"}],"relations":[{"id":"R7318","pred":"arg2Of","subj":"T13610","obj":"T13609"},{"id":"R7319","pred":"arg2Of","subj":"T13614","obj":"T13610"},{"id":"R7320","pred":"arg1Of","subj":"T13614","obj":"T13611"},{"id":"R7321","pred":"arg2Of","subj":"T13614","obj":"T13612"},{"id":"R7322","pred":"arg1Of","subj":"T13614","obj":"T13613"},{"id":"R7323","pred":"arg1Of","subj":"T13614","obj":"T13615"},{"id":"R7324","pred":"arg2Of","subj":"T13617","obj":"T13615"},{"id":"R7325","pred":"arg1Of","subj":"T13617","obj":"T13616"},{"id":"R7326","pred":"modOf","subj":"T13620","obj":"T13609"},{"id":"R7327","pred":"arg1Of","subj":"T13620","obj":"T13618"},{"id":"R7328","pred":"arg2Of","subj":"T13621","obj":"T13620"},{"id":"R7329","pred":"arg1Of","subj":"T13623","obj":"T13609"},{"id":"R7330","pred":"arg1Of","subj":"T13623","obj":"T13610"},{"id":"R7331","pred":"arg1Of","subj":"T13623","obj":"T13619"},{"id":"R7332","pred":"arg1Of","subj":"T13623","obj":"T13620"},{"id":"R7333","pred":"arg1Of","subj":"T13623","obj":"T13621"},{"id":"R7334","pred":"arg1Of","subj":"T13623","obj":"T13622"},{"id":"R7335","pred":"arg2Of","subj":"T13624","obj":"T13623"},{"id":"R7336","pred":"arg1Of","subj":"T13627","obj":"T13624"},{"id":"R7337","pred":"arg1Of","subj":"T13627","obj":"T13625"},{"id":"R7338","pred":"arg1Of","subj":"T13627","obj":"T13626"},{"id":"R7339","pred":"arg1Of","subj":"T13627","obj":"T13628"},{"id":"R7340","pred":"arg2Of","subj":"T13627","obj":"T13629"},{"id":"R7341","pred":"arg2Of","subj":"T13629","obj":"T13628"},{"id":"R7342","pred":"arg2Of","subj":"T13631","obj":"T13630"},{"id":"R7343","pred":"arg1Of","subj":"T13631","obj":"T13632"},{"id":"R7344","pred":"arg2Of","subj":"T13633","obj":"T13632"},{"id":"R7345","pred":"arg1Of","subj":"T13633","obj":"T13634"},{"id":"R7346","pred":"arg1Of","subj":"T13638","obj":"T13636"},{"id":"R7347","pred":"arg1Of","subj":"T13638","obj":"T13637"},{"id":"R7348","pred":"arg1Of","subj":"T13638","obj":"T13639"},{"id":"R7349","pred":"arg1Of","subj":"T13638","obj":"T13643"},{"id":"R7350","pred":"arg2Of","subj":"T13638","obj":"T13644"},{"id":"R7351","pred":"arg2Of","subj":"T13642","obj":"T13639"},{"id":"R7352","pred":"arg1Of","subj":"T13642","obj":"T13640"},{"id":"R7353","pred":"arg1Of","subj":"T13642","obj":"T13641"},{"id":"R7354","pred":"arg1Of","subj":"T13644","obj":"T13630"},{"id":"R7355","pred":"arg1Of","subj":"T13644","obj":"T13635"},{"id":"R7356","pred":"arg2Of","subj":"T13644","obj":"T13643"},{"id":"R7357","pred":"arg1Of","subj":"T13644","obj":"T13645"},{"id":"R7358","pred":"arg1Of","subj":"T13644","obj":"T13659"},{"id":"R7359","pred":"arg2Of","subj":"T13646","obj":"T13645"},{"id":"R7360","pred":"arg1Of","subj":"T13646","obj":"T13647"},{"id":"R7361","pred":"arg1Of","subj":"T13646","obj":"T13654"},{"id":"R7362","pred":"arg1Of","subj":"T13649","obj":"T13648"},{"id":"R7363","pred":"arg1Of","subj":"T13649","obj":"T13650"},{"id":"R7364","pred":"arg1Of","subj":"T13650","obj":"T13652"},{"id":"R7365","pred":"arg2Of","subj":"T13651","obj":"T13650"},{"id":"R7366","pred":"arg2Of","subj":"T13652","obj":"T13647"},{"id":"R7367","pred":"arg2Of","subj":"T13653","obj":"T13652"},{"id":"R7368","pred":"arg1Of","subj":"T13654","obj":"T13656"},{"id":"R7369","pred":"arg2Of","subj":"T13655","obj":"T13654"},{"id":"R7370","pred":"arg3Of","subj":"T13657","obj":"T13654"},{"id":"R7371","pred":"arg1Of","subj":"T13657","obj":"T13658"},{"id":"R7372","pred":"arg1Of","subj":"T13660","obj":"T13661"},{"id":"R7373","pred":"arg1Of","subj":"T13661","obj":"T13663"},{"id":"R7374","pred":"arg2Of","subj":"T13662","obj":"T13661"},{"id":"R7375","pred":"arg1Of","subj":"T13664","obj":"T13665"},{"id":"R7376","pred":"arg2Of","subj":"T13665","obj":"T13663"},{"id":"R7377","pred":"arg2Of","subj":"T13666","obj":"T13665"},{"id":"R7378","pred":"arg1Of","subj":"T13670","obj":"T13660"},{"id":"R7379","pred":"arg1Of","subj":"T13670","obj":"T13662"},{"id":"R7380","pred":"arg1Of","subj":"T13670","obj":"T13664"},{"id":"R7381","pred":"arg1Of","subj":"T13670","obj":"T13666"},{"id":"R7382","pred":"arg1Of","subj":"T13670","obj":"T13667"},{"id":"R7383","pred":"arg1Of","subj":"T13670","obj":"T13668"},{"id":"R7384","pred":"arg1Of","subj":"T13670","obj":"T13669"},{"id":"R7385","pred":"arg2Of","subj":"T13671","obj":"T13659"},{"id":"R7386","pred":"arg1Of","subj":"T13671","obj":"T13670"},{"id":"R7387","pred":"arg1Of","subj":"T13671","obj":"T13672"},{"id":"R7388","pred":"arg1Of","subj":"T13671","obj":"T13673"},{"id":"R7389","pred":"arg1Of","subj":"T13671","obj":"T13674"},{"id":"R7390","pred":"arg2Of","subj":"T13675","obj":"T13674"},{"id":"R7391","pred":"arg1Of","subj":"T13675","obj":"T13676"},{"id":"R7392","pred":"arg1Of","subj":"T13675","obj":"T13677"},{"id":"R7393","pred":"arg3Of","subj":"T13678","obj":"T13659"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T13847","span":{"begin":204,"end":209},"obj":"Protein"},{"id":"T13846","span":{"begin":30,"end":35},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T13946","span":{"begin":321,"end":324},"obj":"http://www.uniprot.org/uniprot/P09693"},{"id":"T13945","span":{"begin":192,"end":195},"obj":"http://www.uniprot.org/uniprot/P09693"},{"id":"T13943","span":{"begin":321,"end":324},"obj":"http://www.uniprot.org/uniprot/P07766"},{"id":"T13942","span":{"begin":192,"end":195},"obj":"http://www.uniprot.org/uniprot/P07766"},{"id":"T13940","span":{"begin":321,"end":324},"obj":"http://www.uniprot.org/uniprot/P04234"},{"id":"T13939","span":{"begin":192,"end":195},"obj":"http://www.uniprot.org/uniprot/P04234"},{"id":"T13937","span":{"begin":321,"end":324},"obj":"http://www.uniprot.org/uniprot/P20963"},{"id":"T13936","span":{"begin":192,"end":195},"obj":"http://www.uniprot.org/uniprot/P20963"},{"id":"T13930","span":{"begin":204,"end":209},"obj":"http://www.uniprot.org/uniprot/Q16552"},{"id":"T13929","span":{"begin":30,"end":35},"obj":"http://www.uniprot.org/uniprot/Q16552"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"GO-BP","denotations":[{"id":"T13558","span":{"begin":90,"end":118},"obj":"http://purl.obolibrary.org/obo/GO_0035556"},{"id":"T13557","span":{"begin":90,"end":118},"obj":"http://purl.obolibrary.org/obo/GO_0036499"},{"id":"T13556","span":{"begin":90,"end":118},"obj":"http://purl.obolibrary.org/obo/GO_0036500"},{"id":"T13555","span":{"begin":90,"end":118},"obj":"http://purl.obolibrary.org/obo/GO_0036498"},{"id":"T13554","span":{"begin":97,"end":109},"obj":"http://purl.obolibrary.org/obo/GO_0009293"},{"id":"T13552","span":{"begin":90,"end":109},"obj":"http://purl.obolibrary.org/obo/GO_0007165"},{"id":"T13550","span":{"begin":90,"end":96},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T13545","span":{"begin":204,"end":220},"obj":"http://purl.obolibrary.org/obo/GO_0032620"},{"id":"T13544","span":{"begin":30,"end":46},"obj":"http://purl.obolibrary.org/obo/GO_0032620"},{"id":"T13539","span":{"begin":204,"end":220},"obj":"http://purl.obolibrary.org/obo/GO_0032660"},{"id":"T13538","span":{"begin":30,"end":46},"obj":"http://purl.obolibrary.org/obo/GO_0032660"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"GO-MF","denotations":[{"id":"T13856","span":{"begin":204,"end":209},"obj":"http://purl.obolibrary.org/obo/GO_0030367"},{"id":"T13855","span":{"begin":30,"end":35},"obj":"http://purl.obolibrary.org/obo/GO_0030367"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"sentences","denotations":[{"id":"T13530","span":{"begin":134,"end":397},"obj":"Sentence"},{"id":"T13529","span":{"begin":0,"end":133},"obj":"Sentence"},{"id":"T130","span":{"begin":0,"end":133},"obj":"Sentence"},{"id":"T131","span":{"begin":134,"end":397},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"simple1","denotations":[{"id":"T13921","span":{"begin":204,"end":209},"obj":"Protein"},{"id":"T13920","span":{"begin":30,"end":35},"obj":"Protein"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"DLUT931","denotations":[{"id":"T13990","span":{"begin":175,"end":183},"obj":"Negative_regulation"},{"id":"T13989","span":{"begin":187,"end":203},"obj":"Positive_regulation"},{"id":"T13988","span":{"begin":210,"end":220},"obj":"Gene_expression"},{"id":"T13987","span":{"begin":20,"end":29},"obj":"Positive_regulation"},{"id":"T13986","span":{"begin":36,"end":46},"obj":"Gene_expression"},{"id":"T13977","span":{"begin":204,"end":209},"obj":"Protein"},{"id":"T13976","span":{"begin":30,"end":35},"obj":"Protein"}],"relations":[{"id":"R7608","pred":"themeOf","subj":"T13976","obj":"T13986"},{"id":"R7609","pred":"themeOf","subj":"T13977","obj":"T13988"},{"id":"R7616","pred":"themeOf","subj":"T13986","obj":"T13987"},{"id":"R7617","pred":"themeOf","subj":"T13988","obj":"T13989"},{"id":"R7618","pred":"themeOf","subj":"T13989","obj":"T13990"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T14367","span":{"begin":16,"end":58},"obj":"Positive_regulation"},{"id":"T14361","span":{"begin":155,"end":233},"obj":"Negative_regulation"},{"id":"T14359","span":{"begin":0,"end":58},"obj":"Gene_expression"},{"id":"T14358","span":{"begin":184,"end":220},"obj":"Gene_expression"},{"id":"T14354","span":{"begin":204,"end":209},"obj":"Protein"},{"id":"T14352","span":{"begin":187,"end":203},"obj":"Protein"},{"id":"T14338","span":{"begin":50,"end":57},"obj":"Entity"},{"id":"T14337","span":{"begin":283,"end":296},"obj":"Entity"},{"id":"T14329","span":{"begin":30,"end":35},"obj":"Protein"},{"id":"T14328","span":{"begin":50,"end":52},"obj":"Protein"},{"id":"T14327","span":{"begin":152,"end":155},"obj":"Protein"},{"id":"T14322","span":{"begin":316,"end":324},"obj":"Protein"},{"id":"T14321","span":{"begin":257,"end":273},"obj":"Entity"}],"relations":[{"id":"R7924","pred":"themeOf","subj":"T14329","obj":"T14359"},{"id":"R7930","pred":"themeOf","subj":"T14354","obj":"T14358"},{"id":"R7932","pred":"themeOf","subj":"T14358","obj":"T14361"},{"id":"R7933","pred":"themeOf","subj":"T14359","obj":"T14367"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T14101","span":{"begin":396,"end":397},"obj":"."},{"id":"T14100","span":{"begin":395,"end":396},"obj":"-RRB-"},{"id":"T14099","span":{"begin":391,"end":395},"obj":"CD"},{"id":"T14098","span":{"begin":389,"end":390},"obj":"NNP"},{"id":"T14097","span":{"begin":387,"end":388},"obj":"NNP"},{"id":"T14096","span":{"begin":385,"end":386},"obj":":"},{"id":"T14095","span":{"begin":373,"end":385},"obj":"RB"},{"id":"T14094","span":{"begin":371,"end":372},"obj":","},{"id":"T14093","span":{"begin":366,"end":371},"obj":"NN"},{"id":"T14092","span":{"begin":363,"end":365},"obj":"CD"},{"id":"T14091","span":{"begin":361,"end":362},"obj":"NN"},{"id":"T14090","span":{"begin":358,"end":360},"obj":"CD"},{"id":"T14089","span":{"begin":351,"end":357},"obj":"CC"},{"id":"T14088","span":{"begin":348,"end":350},"obj":"CD"},{"id":"T14087","span":{"begin":346,"end":347},"obj":"NN"},{"id":"T14086","span":{"begin":343,"end":345},"obj":"CD"},{"id":"T14085","span":{"begin":339,"end":342},"obj":"CC"},{"id":"T14084","span":{"begin":337,"end":338},"obj":"CD"},{"id":"T14083","span":{"begin":335,"end":336},"obj":"NN"},{"id":"T14082","span":{"begin":332,"end":334},"obj":"CD"},{"id":"T14081","span":{"begin":331,"end":332},"obj":"-LRB-"},{"id":"T14080","span":{"begin":325,"end":330},"obj":"RB"},{"id":"T14079","span":{"begin":316,"end":324},"obj":"JJ"},{"id":"T14078","span":{"begin":311,"end":315},"obj":"IN"},{"id":"T14077","span":{"begin":300,"end":310},"obj":"NN"},{"id":"T14076","span":{"begin":297,"end":299},"obj":"IN"},{"id":"T14075","span":{"begin":283,"end":296},"obj":"NN"},{"id":"T14074","span":{"begin":279,"end":282},"obj":"CC"},{"id":"T14073","span":{"begin":274,"end":278},"obj":"NNP"},{"id":"T14072","span":{"begin":272,"end":273},"obj":","},{"id":"T14071","span":{"begin":263,"end":272},"obj":"NN"},{"id":"T14070","span":{"begin":257,"end":262},"obj":"JJ"},{"id":"T14069","span":{"begin":252,"end":256},"obj":"IN"},{"id":"T14068","span":{"begin":239,"end":251},"obj":"VBN"},{"id":"T14067","span":{"begin":234,"end":238},"obj":"WRB"},{"id":"T14066","span":{"begin":225,"end":233},"obj":"VBN"},{"id":"T14065","span":{"begin":221,"end":224},"obj":"VBD"},{"id":"T14064","span":{"begin":210,"end":220},"obj":"NN"},{"id":"T14063","span":{"begin":204,"end":209},"obj":"NN"},{"id":"T14062","span":{"begin":187,"end":203},"obj":"JJ"},{"id":"T14061","span":{"begin":184,"end":186},"obj":"IN"},{"id":"T14060","span":{"begin":175,"end":183},"obj":"NN"},{"id":"T14059","span":{"begin":163,"end":174},"obj":"JJ"},{"id":"T14058","span":{"begin":160,"end":162},"obj":"DT"},{"id":"T14057","span":{"begin":158,"end":159},"obj":","},{"id":"T14056","span":{"begin":157,"end":158},"obj":"CD"},{"id":"T14055","span":{"begin":152,"end":156},"obj":"NNP"},{"id":"T14054","span":{"begin":149,"end":151},"obj":"IN"},{"id":"T14053","span":{"begin":137,"end":148},"obj":"VBN"},{"id":"T14052","span":{"begin":134,"end":136},"obj":"IN"},{"id":"T14051","span":{"begin":132,"end":133},"obj":"."},{"id":"T14050","span":{"begin":124,"end":132},"obj":"VBN"},{"id":"T14049","span":{"begin":119,"end":123},"obj":"VBD"},{"id":"T14048","span":{"begin":110,"end":118},"obj":"NNS"},{"id":"T14047","span":{"begin":97,"end":109},"obj":"NN"},{"id":"T14046","span":{"begin":90,"end":96},"obj":"NN"},{"id":"T14045","span":{"begin":84,"end":89},"obj":"WDT"},{"id":"T14044","span":{"begin":79,"end":83},"obj":"VB"},{"id":"T14043","span":{"begin":76,"end":78},"obj":"TO"},{"id":"T14042","span":{"begin":66,"end":75},"obj":"JJ"},{"id":"T14041","span":{"begin":62,"end":65},"obj":"VBD"},{"id":"T14040","span":{"begin":59,"end":61},"obj":"PRP"},{"id":"T14039","span":{"begin":57,"end":58},"obj":","},{"id":"T14038","span":{"begin":53,"end":57},"obj":"NNP"},{"id":"T14037","span":{"begin":50,"end":52},"obj":"NNP"},{"id":"T14036","span":{"begin":47,"end":49},"obj":"IN"},{"id":"T14035","span":{"begin":36,"end":46},"obj":"NN"},{"id":"T14034","span":{"begin":30,"end":35},"obj":"NN"},{"id":"T14033","span":{"begin":20,"end":29},"obj":"VBN"},{"id":"T14032","span":{"begin":16,"end":19},"obj":"DT"},{"id":"T14031","span":{"begin":7,"end":15},"obj":"VBN"},{"id":"T14030","span":{"begin":0,"end":6},"obj":"VBG"}],"relations":[{"id":"R7646","pred":"aux","subj":"T14030","obj":"T14031"},{"id":"R7647","pred":"ccomp","subj":"T14031","obj":"T14041"},{"id":"R7648","pred":"det","subj":"T14032","obj":"T14035"},{"id":"R7649","pred":"amod","subj":"T14033","obj":"T14035"},{"id":"R7650","pred":"compound","subj":"T14034","obj":"T14035"},{"id":"R7651","pred":"dobj","subj":"T14035","obj":"T14031"},{"id":"R7652","pred":"prep","subj":"T14036","obj":"T14035"},{"id":"R7653","pred":"compound","subj":"T14037","obj":"T14038"},{"id":"R7654","pred":"pobj","subj":"T14038","obj":"T14036"},{"id":"R7655","pred":"punct","subj":"T14039","obj":"T14041"},{"id":"R7656","pred":"nsubj","subj":"T14040","obj":"T14041"},{"id":"R7657","pred":"ROOT","subj":"T14041","obj":"T14041"},{"id":"R7658","pred":"acomp","subj":"T14042","obj":"T14041"},{"id":"R7659","pred":"aux","subj":"T14043","obj":"T14044"},{"id":"R7660","pred":"xcomp","subj":"T14044","obj":"T14041"},{"id":"R7661","pred":"nsubj","subj":"T14045","obj":"T14046"},{"id":"R7662","pred":"nmod","subj":"T14046","obj":"T14048"},{"id":"R7663","pred":"compound","subj":"T14047","obj":"T14048"},{"id":"R7664","pred":"nsubjpass","subj":"T14048","obj":"T14050"},{"id":"R7665","pred":"auxpass","subj":"T14049","obj":"T14050"},{"id":"R7666","pred":"ccomp","subj":"T14050","obj":"T14044"},{"id":"R7667","pred":"punct","subj":"T14051","obj":"T14041"},{"id":"R7668","pred":"mark","subj":"T14052","obj":"T14053"},{"id":"R7669","pred":"advcl","subj":"T14053","obj":"T14066"},{"id":"R7670","pred":"prep","subj":"T14054","obj":"T14053"},{"id":"R7671","pred":"pobj","subj":"T14055","obj":"T14054"},{"id":"R7672","pred":"nummod","subj":"T14056","obj":"T14055"},{"id":"R7673","pred":"punct","subj":"T14057","obj":"T14055"},{"id":"R7674","pred":"det","subj":"T14058","obj":"T14060"},{"id":"R7675","pred":"amod","subj":"T14059","obj":"T14060"},{"id":"R7676","pred":"nsubjpass","subj":"T14060","obj":"T14066"},{"id":"R7677","pred":"prep","subj":"T14061","obj":"T14060"},{"id":"R7678","pred":"amod","subj":"T14062","obj":"T14064"},{"id":"R7679","pred":"compound","subj":"T14063","obj":"T14064"},{"id":"R7680","pred":"pobj","subj":"T14064","obj":"T14061"},{"id":"R7681","pred":"auxpass","subj":"T14065","obj":"T14066"},{"id":"R7682","pred":"ROOT","subj":"T14066","obj":"T14066"},{"id":"R7683","pred":"advmod","subj":"T14067","obj":"T14068"},{"id":"R7684","pred":"advcl","subj":"T14068","obj":"T14066"},{"id":"R7685","pred":"prep","subj":"T14069","obj":"T14068"},{"id":"R7686","pred":"amod","subj":"T14070","obj":"T14071"},{"id":"R7687","pred":"pobj","subj":"T14071","obj":"T14069"},{"id":"R7688","pred":"punct","subj":"T14072","obj":"T14071"},{"id":"R7689","pred":"conj","subj":"T14073","obj":"T14071"},{"id":"R7690","pred":"cc","subj":"T14074","obj":"T14073"},{"id":"R7691","pred":"conj","subj":"T14075","obj":"T14073"},{"id":"R7692","pred":"prep","subj":"T14076","obj":"T14068"},{"id":"R7693","pred":"pobj","subj":"T14077","obj":"T14076"},{"id":"R7694","pred":"prep","subj":"T14078","obj":"T14077"},{"id":"R7695","pred":"pobj","subj":"T14079","obj":"T14078"},{"id":"R7696","pred":"advmod","subj":"T14080","obj":"T14079"},{"id":"R7697","pred":"punct","subj":"T14081","obj":"T14083"},{"id":"R7698","pred":"nummod","subj":"T14082","obj":"T14083"},{"id":"R7699","pred":"nmod","subj":"T14083","obj":"T14091"},{"id":"R7700","pred":"nummod","subj":"T14084","obj":"T14083"},{"id":"R7701","pred":"cc","subj":"T14085","obj":"T14083"},{"id":"R7702","pred":"nummod","subj":"T14086","obj":"T14087"},{"id":"R7703","pred":"conj","subj":"T14087","obj":"T14083"},{"id":"R7704","pred":"nummod","subj":"T14088","obj":"T14091"},{"id":"R7705","pred":"cc","subj":"T14089","obj":"T14088"},{"id":"R7706","pred":"conj","subj":"T14090","obj":"T14088"},{"id":"R7707","pred":"dep","subj":"T14091","obj":"T14079"},{"id":"R7708","pred":"nummod","subj":"T14092","obj":"T14093"},{"id":"R7709","pred":"appos","subj":"T14093","obj":"T14091"},{"id":"R7710","pred":"punct","subj":"T14094","obj":"T14093"},{"id":"R7711","pred":"conj","subj":"T14095","obj":"T14091"},{"id":"R7712","pred":"punct","subj":"T14096","obj":"T14099"},{"id":"R7713","pred":"compound","subj":"T14097","obj":"T14098"},{"id":"R7714","pred":"compound","subj":"T14098","obj":"T14099"},{"id":"R7715","pred":"npadvmod","subj":"T14099","obj":"T14066"},{"id":"R7716","pred":"punct","subj":"T14100","obj":"T14099"},{"id":"R7717","pred":"punct","subj":"T14101","obj":"T14066"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T13884","span":{"begin":263,"end":272},"obj":"Negative_regulation"},{"id":"T13883","span":{"begin":316,"end":324},"obj":"Protein"},{"id":"T13882","span":{"begin":257,"end":262},"obj":"Protein"},{"id":"T13881","span":{"begin":192,"end":195},"obj":"Protein"},{"id":"T13880","span":{"begin":152,"end":155},"obj":"Protein"}],"relations":[{"id":"R7559","pred":"themeOf","subj":"T13882","obj":"T13884"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}

{"project":"testone","denotations":[{"id":"T13317","span":{"begin":210,"end":220},"obj":"Gene_expression"},{"id":"T13316","span":{"begin":196,"end":203},"obj":"Positive_regulation"},{"id":"T13315","span":{"begin":175,"end":183},"obj":"Negative_regulation"},{"id":"T13314","span":{"begin":36,"end":46},"obj":"Gene_expression"},{"id":"T13313","span":{"begin":20,"end":29},"obj":"Positive_regulation"},{"id":"T13304","span":{"begin":204,"end":209},"obj":"Protein"},{"id":"T13303","span":{"begin":30,"end":35},"obj":"Protein"}],"relations":[{"id":"R7253","pred":"themeOf","subj":"T13303","obj":"T13314"},{"id":"R7254","pred":"themeOf","subj":"T13304","obj":"T13317"},{"id":"R7261","pred":"themeOf","subj":"T13314","obj":"T13313"},{"id":"R7262","pred":"themeOf","subj":"T13316","obj":"T13315"},{"id":"R7263","pred":"themeOf","subj":"T13317","obj":"T13316"}],"text":"Having observed the increased IL-17 production in RA PBMC, it was important to know which signal transduction pathways were involved. As illustrated in Fig. 3, an significant decrease in anti-CD3-induced IL-17 production was observed when co-incubated with NF-κB inhibitor, PDTC and dexamethasone in comparison with anti-CD3 alone (38 ± 5 and 54 ± 11 versus 98 ± 19 pg/ml, respectively; P \u003c 0.05)."}